Danio rerio

10 known processes

chrdl2

chordin-like 2

(Aliases: chl,si:dkey-11j5.7,si:dkey-11j5.7-like)

chrdl2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.100
cellular macromolecule metabolic processGO:00442603910.097
nitrogen compound metabolic processGO:00068073190.085
generation of neuronsGO:00486993850.082
maintenance of locationGO:005123540.077
regulation of metabolic processGO:00192223590.072
cellular aromatic compound metabolic processGO:00067252950.070
sensory organ developmentGO:00074233930.070
response to chemicalGO:00422213200.069
regulation of cellular metabolic processGO:00313233200.065
rna metabolic processGO:00160702190.064
cellular nitrogen compound metabolic processGO:00346412900.063
signal transductionGO:00071654550.057
heterocycle metabolic processGO:00464832900.053
agingGO:000756820.053
regulation of macromolecule metabolic processGO:00602553170.053
head developmentGO:00603223030.052
cellular protein catabolic processGO:004425740.052
organic cyclic compound metabolic processGO:19013603010.051
cellular biosynthetic processGO:00442492860.050
gene expressionGO:00104672520.049
negative regulation of biological processGO:00485193040.048
neuron differentiationGO:00301823530.048
organic substance biosynthetic processGO:19015762890.047
stem cell maintenanceGO:001982740.047
nucleic acid metabolic processGO:00903042440.046
nucleobase containing compound biosynthetic processGO:00346542050.046
biosynthetic processGO:00090582940.046
cell surface receptor signaling pathwayGO:00071663250.045
central nervous system developmentGO:00074173870.045
macromolecule biosynthetic processGO:00090592270.044
regulation of developmental processGO:00507932470.044
regulation of rna metabolic processGO:00512522240.044
modification dependent protein catabolic processGO:001994130.044
regulation of primary metabolic processGO:00800903110.044
organic cyclic compound biosynthetic processGO:19013622230.044
response to external stimulusGO:00096052640.042
regulation of nitrogen compound metabolic processGO:00511712510.042
tube morphogenesisGO:00352393490.042
regulation of multicellular organismal developmentGO:20000262230.041
skeletal system developmentGO:00015011810.041
regulation of biosynthetic processGO:00098892500.041
cell part morphogenesisGO:00329902460.040
proteolysis involved in cellular protein catabolic processGO:005160330.040
immune system processGO:00023762410.039
aromatic compound biosynthetic processGO:00194382170.039
embryonic organ developmentGO:00485683810.039
amine metabolic processGO:000930820.039
nucleobase containing compound metabolic processGO:00061392740.038
heterocycle biosynthetic processGO:00181302150.038
regulation of response to stimulusGO:00485832690.037
cell projection organizationGO:00300302840.037
regulation of nucleobase containing compound metabolic processGO:00192192500.037
positive regulation of transportGO:005105020.037
negative regulation of cellular processGO:00485232830.037
cell projection morphogenesisGO:00488582440.036
regulation of gene expressionGO:00104682650.035
positive regulation of cell cycleGO:004578730.035
multicellular organism growthGO:003526440.035
nucleic acid templated transcriptionGO:00976591810.035
regulation of macromolecule biosynthetic processGO:00105562250.035
cellular macromolecule biosynthetic processGO:00346452240.035
regulation of signalingGO:00230512350.035
response to organic substanceGO:00100331530.035
gtp metabolic processGO:004603940.035
immune system developmentGO:00025201910.034
modification dependent macromolecule catabolic processGO:004363230.034
transcription dna templatedGO:00063511810.034
guanosine containing compound metabolic processGO:190106840.033
retina development in camera type eyeGO:00600411460.033
cellular ketone metabolic processGO:0042180110.033
brain developmentGO:00074202930.033
regulation of cellular biosynthetic processGO:00313262450.033
cellular nitrogen compound biosynthetic processGO:00442712180.033
stem cell proliferationGO:007208940.032
regulation of cytokine productionGO:000181730.032
regulation of multicellular organismal processGO:00512392770.030
cell morphogenesisGO:00009022890.030
hematopoietic or lymphoid organ developmentGO:00485341910.030
regulation of cellular amine metabolic processGO:003323800.030
camera type eye developmentGO:00430102220.030
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.030
regulation of cellular amino acid metabolic processGO:000652100.030
regulation of cell differentiationGO:00455951420.030
single organism membrane fusionGO:004480120.030
regulation of cellular macromolecule biosynthetic processGO:20001122220.030
cell migrationGO:00164772370.029
morphogenesis of an epitheliumGO:00020093330.029
ubiquitin dependent protein catabolic processGO:000651130.029
cellular component movementGO:00069283350.028
digestive system developmentGO:00551232890.028
protein metabolic processGO:00195381830.028
rna biosynthetic processGO:00327741810.028
cellular amine metabolic processGO:004410620.028
cellular component morphogenesisGO:00329893360.028
mesenchyme developmentGO:00604851270.027
eye developmentGO:00016542770.027
proteasomal protein catabolic processGO:001049820.027
regulation of nervous system developmentGO:0051960900.027
neuron developmentGO:00486662620.027
guanosine containing compound catabolic processGO:190106920.027
positive regulation of catabolic processGO:000989640.027
hemopoiesisGO:00300971830.027
regulation of transcription dna templatedGO:00063552130.027
single organism metabolic processGO:00447102170.027
cellular response to chemical stimulusGO:00708871570.027
lipid storageGO:001991510.026
cartilage developmentGO:0051216960.026
regulation of neurogenesisGO:0050767870.026
digestive tract morphogenesisGO:00485462310.026
embryo development ending in birth or egg hatchingGO:00097922710.026
neuron projection morphogenesisGO:00488121610.026
tissue remodelingGO:004877140.026
regulation of cell communicationGO:00106462320.026
regulation of sequestering of calcium ionGO:005128240.025
gland developmentGO:00487321430.025
response to external biotic stimulusGO:0043207970.025
negative regulation of protein phosphorylationGO:000193340.025
cognitionGO:005089010.025
cellular protein metabolic processGO:00442671290.025
regulation of metal ion transportGO:001095940.025
gtp catabolic processGO:000618420.024
digestive tract developmentGO:00485652650.024
neuron projection developmentGO:00311751800.024
regulation of cellular ketone metabolic processGO:001056570.024
axon developmentGO:00615641660.024
organelle organizationGO:00069962270.024
organelle fusionGO:004828430.024
regulation of multicellular organism growthGO:004001440.023
b cell activationGO:004211320.023
angiogenesisGO:00015251580.023
establishment of protein localization to organelleGO:007259440.023
determination of bilateral symmetryGO:00098552040.023
negative regulation of cell communicationGO:0010648960.023
extrinsic apoptotic signaling pathwayGO:009719130.023
cellular response to organic substanceGO:00713101050.023
single organism localizationGO:19025782250.023
negative regulation of sequestering of calcium ionGO:005128340.023
cellular response to external stimulusGO:007149620.023
exocytosisGO:000688710.023
regulation of rna biosynthetic processGO:20011412130.023
regulation of cell activationGO:005086510.022
regulation of dendrite developmentGO:005077330.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
cell motilityGO:00488702440.022
heart developmentGO:00075073130.022
positive regulation of cellular processGO:00485222010.022
locomotionGO:00400113130.022
oxoacid metabolic processGO:0043436310.022
single organism organelle organizationGO:19025891990.022
nuclear transportGO:005116940.022
small molecule metabolic processGO:0044281770.022
positive regulation of cellular catabolic processGO:003133130.021
regulation of protein transportGO:005122330.021
cellular response to lipopolysaccharideGO:007122230.021
vasculature developmentGO:00019442780.021
multi organism processGO:00517041340.021
chordate embryonic developmentGO:00430092710.021
regulation of nucleic acid templated transcriptionGO:19035062130.021
stem cell differentiationGO:00488631170.021
regulation of cell shapeGO:000836010.021
secondary metabolic processGO:001974830.021
negative regulation of signalingGO:0023057960.020
positive regulation of biological processGO:00485182530.020
sequestering of metal ionGO:005123830.020
cellular protein modification processGO:00064641000.020
regulation of dendrite morphogenesisGO:004881430.020
adult behaviorGO:003053420.020
antimicrobial humoral responseGO:001973020.020
regulation of signal transductionGO:00099662250.020
cilium assemblyGO:0042384580.020
regulation of protein ubiquitinationGO:003139630.020
regulation of cytoplasmic transportGO:190364940.020
positive regulation of cellular component biogenesisGO:004408930.020
specification of symmetryGO:00097992040.020
cellular amino acid metabolic processGO:000652070.020
nucleocytoplasmic transportGO:000691340.020
positive regulation of stress activated mapk cascadeGO:003287430.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
nuclear importGO:005117030.019
response to stressGO:00069502630.019
response to drugGO:004249330.019
cell morphogenesis involved in differentiationGO:00009041950.019
regulation of anatomical structure morphogenesisGO:00226031300.019
cellular response to extracellular stimulusGO:003166820.019
leukocyte proliferationGO:007066110.019
cellular response to radiationGO:007147840.019
macromolecule modificationGO:00434121110.019
determination of left right symmetryGO:00073681790.019
developmental growthGO:00485891660.019
peptide transportGO:001583310.019
negative regulation of signal transductionGO:0009968940.019
organonitrogen compound metabolic processGO:1901564740.019
carboxylic acid metabolic processGO:0019752220.019
organic acid metabolic processGO:0006082310.019
hepaticobiliary system developmentGO:0061008980.019
cell morphogenesis involved in neuron differentiationGO:00486671630.019
localization of cellGO:00516742440.018
regulation of bindingGO:005109830.018
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.018
regulation of cell developmentGO:00602841000.018
protein import into nucleusGO:000660630.018
negative regulation of macromolecule metabolic processGO:0010605760.018
neural crest cell differentiationGO:0014033720.018
response to biotic stimulusGO:0009607970.018
transcription from rna polymerase ii promoterGO:0006366800.018
response to corticosteroidGO:003196010.018
cilium organizationGO:0044782710.018
cation transportGO:0006812810.018
cellular response to biotic stimulusGO:007121630.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
membrane fusionGO:006102520.017
regulation of reproductive processGO:200024140.017
response to endogenous stimulusGO:0009719830.017
regulation of neuron differentiationGO:0045664560.017
negative regulation of protein kinase activityGO:000646940.017
neuroblast proliferationGO:000740520.017
regulation of epithelial cell proliferationGO:005067830.017
blood vessel morphogenesisGO:00485142160.017
protein importGO:001703830.017
germ line stem cell maintenanceGO:003071820.017
stem cell divisionGO:001714510.017
cilium morphogenesisGO:0060271850.017
positive regulation of cytokine productionGO:000181920.017
regulation of intracellular protein transportGO:003315730.017
negative regulation of response to stimulusGO:00485851040.017
negative regulation of cytokine productionGO:000181810.017
i kappab kinase nf kappab signalingGO:000724940.017
regulation of establishment of protein localizationGO:007020140.017
response to alkaloidGO:004327920.017
eye morphogenesisGO:00485921440.016
mononuclear cell proliferationGO:003294310.016
regulation of protein catabolic processGO:004217610.016
fin developmentGO:0033333770.016
protein localization to nucleusGO:003450430.016
production of molecular mediator of immune responseGO:000244020.016
regulation of nucleocytoplasmic transportGO:004682220.016
establishment of localizationGO:00512342440.016
blood vessel developmentGO:00015682460.016
response to hormoneGO:0009725480.016
cellular amide metabolic processGO:004360340.016
synaptic growth at neuromuscular junctionGO:005112420.016
skeletal system morphogenesisGO:00487051020.016
positive regulation of cellular amine metabolic processGO:003324000.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
embryonic organ morphogenesisGO:00485622740.016
transportGO:00068102200.016
synaptic transmission cholinergicGO:000727140.016
cellular response to nutrient levelsGO:003166920.016
protein targeting to nucleusGO:004474430.016
female gonad developmentGO:000858540.016
liver developmentGO:0001889960.016
phosphorus metabolic processGO:00067931090.016
regulation of protein targetingGO:190353320.016
phagocytosisGO:000690930.016
negative regulation of secretionGO:005104820.015
single organism transportGO:00447652060.015
sensory system developmentGO:0048880760.015
response to uvGO:000941130.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
positive regulation of cytosolic calcium ion concentrationGO:000720440.015
single organism nuclear importGO:190259330.015
phosphate containing compound metabolic processGO:00067961080.015
ion transportGO:00068111140.015
convergent extensionGO:00600261180.015
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.015
lateral line developmentGO:0048882660.015
protein secretionGO:000930610.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
regulation of protein localization to nucleusGO:190018020.015
regulation of protein import into nucleusGO:004230620.015
cellular response to molecule of bacterial originGO:007121930.015
connective tissue developmentGO:0061448990.015
positive regulation of canonical wnt signaling pathwayGO:009026340.015
negative regulation of metabolic processGO:0009892860.015
mesenchymal cell differentiationGO:0048762870.015
autophagyGO:000691440.015
regulation of protein complex assemblyGO:004325430.015
positive regulation of cellular metabolic processGO:0031325940.015
regulation of response to biotic stimulusGO:000283120.015
hormone transportGO:000991420.014
somitogenesisGO:0001756870.014
system processGO:00030081850.014
cellular response to starvationGO:000926710.014
positive regulation of secretionGO:005104710.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
negative regulation of epithelial cell proliferationGO:005068010.014
protein modification processGO:00362111000.014
response to other organismGO:0051707970.014
sensory organ morphogenesisGO:00905962000.014
regulation of autophagyGO:001050630.014
positive regulation of immune effector processGO:000269930.014
adherens junction organizationGO:003433240.014
hormone secretionGO:004687920.014
negative regulation of catabolic processGO:000989530.014
calcium ion transport into cytosolGO:006040230.014
appendage developmentGO:0048736800.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
regulation of wnt signaling pathwayGO:0030111530.014
hindbrain developmentGO:0030902910.014
myeloid cell differentiationGO:0030099860.014
neuromast developmentGO:0048884460.014
protein dephosphorylationGO:000647030.014
cellular component maintenanceGO:004395430.014
response to glucocorticoidGO:005138410.014
regulation of i kappab kinase nf kappab signalingGO:004312240.014
negative regulation of protein transportGO:005122430.014
carbohydrate homeostasisGO:003350010.014
cellular component assemblyGO:00226071700.013
sequestering of calcium ionGO:005120830.013
neurotransmitter secretionGO:000726920.013
regulation of nucleoside metabolic processGO:000911820.013
muscle structure developmentGO:00610611960.013
cell cycle g1 s phase transitionGO:004484310.013
mitochondrion organizationGO:000700540.013
response to woundingGO:00096111160.013
protein polymerizationGO:005125840.013
pigmentationGO:0043473850.013
regulation of stem cell differentiationGO:200073640.013
growthGO:00400071740.013
apoptotic processGO:00069151160.013
somite developmentGO:0061053960.013
regulation of protein bindingGO:004339330.013
regulation of nucleotide catabolic processGO:003081120.013
positive regulation of translationGO:004572710.013
notochord developmentGO:0030903540.013
regulation of gtp catabolic processGO:003312420.013
negative regulation of kinase activityGO:003367340.013
neurotransmitter transportGO:000683620.013
regulation of inflammatory responseGO:005072720.013
somatic stem cell maintenanceGO:003501910.013
axonogenesisGO:00074091520.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
lymphocyte proliferationGO:004665110.013
response to hexoseGO:000974630.013
response to carbohydrateGO:000974330.012
embryonic skeletal system developmentGO:0048706970.012
embryonic limb morphogenesisGO:003032620.012
development of primary female sexual characteristicsGO:004654540.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
peptidyl serine modificationGO:001820920.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of neural precursor cell proliferationGO:200017730.012
cell fate commitmentGO:0045165990.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
ameboidal type cell migrationGO:00016671430.012
endosomal transportGO:001619720.012
cellular component biogenesisGO:00440851780.012
positive regulation of map kinase activityGO:004340630.012
meiotic nuclear divisionGO:000712640.012
positive regulation of secretion by cellGO:190353210.012
positive regulation of nucleotide catabolic processGO:003081310.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
pancreas developmentGO:0031016840.012
protein localization to plasma membraneGO:007265910.012
regenerationGO:0031099910.012
intracellular signal transductionGO:0035556850.012
response to organic cyclic compoundGO:0014070510.012
regulation of catalytic activityGO:0050790550.012
cell projection assemblyGO:0030031640.012
positive regulation of jnk cascadeGO:004633030.012
regulation of purine nucleotide catabolic processGO:003312120.012
positive regulation of nucleoside metabolic processGO:004597910.012
regulation of ion transmembrane transporter activityGO:003241220.012
response to nutrientGO:000758430.012
negative regulation of multicellular organismal processGO:0051241690.012
regulation of organ growthGO:004662030.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
regulation of biological qualityGO:00650082630.012
negative regulation of nucleobase containing compound metabolic processGO:0045934590.012
response to monosaccharideGO:003428430.012
embryonic hemopoiesisGO:0035162530.012
ribonucleoside monophosphate catabolic processGO:000915840.012
positive regulation of macromolecule metabolic processGO:0010604930.012
forebrain developmentGO:0030900960.012
regulation of blood pressureGO:000821710.012
segmentationGO:0035282970.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
stem cell developmentGO:0048864820.011
membrane invaginationGO:001032410.011
regulation of cellular protein catabolic processGO:190336210.011
cell deathGO:00082191210.011
organism emergence from protective structureGO:007168440.011
mesenchymal cell developmentGO:0014031780.011
action potentialGO:0001508190.011
camera type eye morphogenesisGO:00485931080.011
negative regulation of defense responseGO:003134820.011
programmed cell deathGO:00125011190.011
positive regulation of developmental processGO:0051094500.011
negative regulation of map kinase activityGO:004340720.011
fertilizationGO:000956630.011
regulation of calcium ion transportGO:005192420.011
regulation of synapse assemblyGO:005196330.011
regulation of gtpase activityGO:004308720.011
embryonic skeletal system morphogenesisGO:0048704930.011
transmembrane transportGO:00550851200.011
regulation of neuron projection developmentGO:0010975400.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
regulation of synapse organizationGO:005080730.011
tissue regenerationGO:0042246740.011
cortical actin cytoskeleton organizationGO:003086610.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
positive regulation of epithelial cell proliferationGO:005067910.011
cellular component disassemblyGO:002241110.011
developmental growth involved in morphogenesisGO:0060560860.011
sprouting angiogenesisGO:0002040530.011
cellular response to endogenous stimulusGO:0071495680.011
cell substrate junction assemblyGO:000704420.011
cellular localizationGO:0051641970.011
regulation of cellular response to growth factor stimulusGO:0090287350.011
regulation of protein metabolic processGO:0051246560.011
cellular component assembly involved in morphogenesisGO:00109271070.011
peptidyl lysine acetylationGO:001839420.011
regulation of locomotionGO:0040012550.011
positive regulation of striated muscle tissue developmentGO:004584410.011
regulation of circadian rhythmGO:004275240.011
dorsal ventral pattern formationGO:00099531250.011
cytosolic calcium ion transportGO:006040130.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.010
cell cycleGO:0007049930.010
spinal cord developmentGO:0021510460.010
protein stabilizationGO:005082120.010
compound eye developmentGO:004874920.010
convergent extension involved in gastrulationGO:0060027710.010
positive regulation of lymphocyte mediated immunityGO:000270810.010
neuron projection extensionGO:1990138450.010
interspecies interaction between organismsGO:004441940.010
neural crest cell developmentGO:0014032620.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
cellular response to light stimulusGO:007148240.010
negative regulation of developmental processGO:0051093650.010
wnt signaling pathwayGO:0016055800.010
positive regulation of gtp catabolic processGO:003312610.010
positive regulation of neuron deathGO:190121610.010
positive regulation of metabolic processGO:00098931080.010
cellular response to hormone stimulusGO:0032870390.010
positive regulation of dna metabolic processGO:005105410.010
negative regulation of rna biosynthetic processGO:1902679450.010
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.010
peptidyl serine phosphorylationGO:001810510.010
negative regulation of cellular metabolic processGO:0031324770.010
regulation of synaptic plasticityGO:004816710.010
neuron projection guidanceGO:0097485860.010
purine nucleoside monophosphate catabolic processGO:000912840.010
positive regulation of protein complex assemblyGO:003133420.010
cell substrate adhesionGO:003158940.010
retina morphogenesis in camera type eyeGO:0060042790.010

chrdl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.018
immune system diseaseDOID:291400.017
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.011
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
organ system cancerDOID:005068600.011
musculoskeletal system diseaseDOID:1700.010