Danio rerio

0 known processes

myl2

myosin, light polypeptide 2, regulatory, cardiac, slow

(Aliases: MGC136848,zgc:136848)

myl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heart contractionGO:0060047710.252
Zebrafish Mouse
heart developmentGO:00075073130.217
Zebrafish Mouse
heart morphogenesisGO:00030071560.178
Mouse
cardiac muscle tissue developmentGO:0048738480.147
Zebrafish Mouse
morphogenesis of an epitheliumGO:00020093330.143
specification of symmetryGO:00097992040.136
striated muscle tissue developmentGO:00147061100.131
Zebrafish Mouse
system processGO:00030081850.127
Zebrafish Mouse Worm
cardiac muscle cell developmentGO:0055013200.113
Zebrafish Mouse
embryonic heart tube morphogenesisGO:00031431080.110
muscle structure developmentGO:00610611960.110
Zebrafish Mouse Worm
regulation of heart contractionGO:0008016320.107
Zebrafish
sodium ion transmembrane transportGO:0035725210.106
heart processGO:0003015710.105
Zebrafish Mouse
striated muscle cell developmentGO:00550021080.104
Zebrafish Mouse
tube morphogenesisGO:00352393490.102
muscle tissue developmentGO:00605371100.098
Zebrafish Mouse
muscle cell differentiationGO:00426921390.097
Zebrafish Mouse
determination of bilateral symmetryGO:00098552040.091
transmembrane transportGO:00550851200.090
myofibril assemblyGO:0030239480.084
Zebrafish Mouse
embryonic organ morphogenesisGO:00485622740.082
heart loopingGO:0001947940.081
ventricular cardiac muscle tissue developmentGO:000322930.080
circulatory system processGO:0003013870.076
Zebrafish Mouse
determination of left right symmetryGO:00073681790.071
single organism organelle organizationGO:19025891990.067
Zebrafish Mouse
cellular component morphogenesisGO:00329893360.066
Zebrafish Mouse
organelle assemblyGO:00709251100.066
Zebrafish Mouse
cardiac cell developmentGO:0055006210.061
Zebrafish Mouse
muscle cell developmentGO:00550011150.059
Zebrafish Mouse
larval developmentGO:000216420.055
Worm
blood circulationGO:0008015870.055
Zebrafish Mouse
embryonic heart tube developmentGO:00350501330.052
embryonic organ developmentGO:00485683810.052
determination of heart left right asymmetryGO:00613711170.051
single organism localizationGO:19025782250.049
cardiocyte differentiationGO:0035051440.048
Zebrafish Mouse
cardiac conductionGO:006133730.048
regulation of blood circulationGO:1903522320.047
Zebrafish
regulation of stem cell proliferationGO:007209120.046
detection of mechanical stimulusGO:0050982110.046
fluid transportGO:0042044170.045
cardiac muscle cell differentiationGO:0055007300.045
Zebrafish Mouse
regulation of muscle contractionGO:000693730.044
Worm
organelle organizationGO:00069962270.044
Zebrafish Mouse
ventricular cardiac muscle tissue morphogenesisGO:005501020.043
neurotransmitter secretionGO:000726920.043
somatic muscle developmentGO:000752540.043
establishment of localizationGO:00512342440.042
transportGO:00068102200.041
cell morphogenesisGO:00009022890.041
agingGO:000756820.040
actin filament based movementGO:003004810.039
epithelial tube morphogenesisGO:00605621480.039
neuron differentiationGO:00301823530.039
sarcomere organizationGO:0045214260.038
Zebrafish
regulation of neural precursor cell proliferationGO:200017730.038
compound eye developmentGO:004874920.038
cellular nitrogen compound metabolic processGO:00346412900.037
gastrulationGO:00073692080.037
response to chemicalGO:00422213200.037
regulation of multicellular organismal processGO:00512392770.037
Zebrafish Worm
cell surface receptor signaling pathwayGO:00071663250.037
cellular component biogenesisGO:00440851780.037
Zebrafish Mouse
cellular component assembly involved in morphogenesisGO:00109271070.036
Zebrafish Mouse
heterocycle metabolic processGO:00464832900.036
tissue remodelingGO:004877140.035
cardiac myofibril assemblyGO:005500390.035
Zebrafish Mouse
cellular aromatic compound metabolic processGO:00067252950.035
brain developmentGO:00074202930.035
single organism metabolic processGO:00447102170.035
positive regulation of transportGO:005105020.035
positive regulation of catabolic processGO:000989640.034
locomotionGO:00400113130.034
Worm
neurotransmitter transportGO:000683620.034
calcium ion importGO:007050940.033
ion transmembrane transportGO:0034220910.032
regulation of protein complex assemblyGO:004325430.031
nitrogen compound metabolic processGO:00068073190.031
central nervous system developmentGO:00074173870.031
cell projection morphogenesisGO:00488582440.031
lipid catabolic processGO:001604240.031
actin polymerization or depolymerizationGO:000815420.031
positive regulation of cell cycleGO:004578730.030
maintenance of locationGO:005123540.030
nucleobase containing compound metabolic processGO:00061392740.030
signal transductionGO:00071654550.030
positive regulation of cytosolic calcium ion concentrationGO:000720440.029
regulation of synapse assemblyGO:005196330.029
striated muscle cell differentiationGO:00511461290.029
Zebrafish Mouse
chemosensory behaviorGO:000763510.028
positive regulation of blood circulationGO:190352420.028
Zebrafish
head developmentGO:00603223030.028
protein dephosphorylationGO:000647030.028
regulation of biological qualityGO:00650082630.028
regulation of sodium ion transportGO:000202820.028
cell projection organizationGO:00300302840.028
regulation of synapse organizationGO:005080730.028
startle responseGO:000196440.027
cellular component assemblyGO:00226071700.027
Zebrafish Mouse
cellular component movementGO:00069283350.027
single organism transportGO:00447652060.027
cellular biosynthetic processGO:00442492860.027
adult behaviorGO:003053420.026
regulation of multicellular organismal developmentGO:20000262230.026
ubiquitin dependent protein catabolic processGO:000651130.026
stem cell maintenanceGO:001982740.026
cytokinesisGO:000091030.026
digestive tract morphogenesisGO:00485462310.026
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.025
rna localizationGO:000640340.025
sleepGO:003043110.025
meiotic nuclear divisionGO:000712640.025
inorganic cation transmembrane transportGO:0098662500.025
stem cell proliferationGO:007208940.025
blood vessel developmentGO:00015682460.025
regulation of synaptic growth at neuromuscular junctionGO:000858210.025
negative regulation of synapse assemblyGO:005196420.024
post embryonic organ developmentGO:004856940.024
synaptic growth at neuromuscular junctionGO:005112420.024
establishment of protein localization to organelleGO:007259440.024
response to external stimulusGO:00096052640.023
photoreceptor cell fate specificationGO:004370410.023
vasculature developmentGO:00019442780.023
carbohydrate biosynthetic processGO:001605110.023
negative regulation of kinase activityGO:003367340.023
cilium assemblyGO:0042384580.023
cognitionGO:005089010.023
organic cyclic compound metabolic processGO:19013603010.023
neuron projection developmentGO:00311751800.022
regulation of system processGO:0044057400.022
Zebrafish Worm
cell part morphogenesisGO:00329902460.022
cation transmembrane transportGO:0098655650.022
positive regulation of cellular catabolic processGO:003133130.022
regulation of transmembrane transporter activityGO:002289820.022
lipid storageGO:001991510.021
cation transportGO:0006812810.021
regulation of tube sizeGO:003515020.021
angiogenesisGO:00015251580.021
outflow tract morphogenesisGO:000315110.021
organic substance biosynthetic processGO:19015762890.021
regulation of meiotic cell cycleGO:005144510.021
regulation of cell communicationGO:00106462320.021
sodium ion transportGO:0006814240.020
regulation of blood vessel sizeGO:005088020.020
regulation of reproductive processGO:200024140.020
inorganic ion transmembrane transportGO:0098660570.020
regulation of developmental processGO:00507932470.020
organic acid metabolic processGO:0006082310.020
neuron neuron synaptic transmissionGO:000727010.020
ion transportGO:00068111140.020
cytoskeleton organizationGO:0007010960.020
Zebrafish Mouse
regulation of response to stimulusGO:00485832690.020
Worm
positive regulation of biological processGO:00485182530.020
Zebrafish
muscle system processGO:0003012200.020
Mouse Worm
sensory perception of painGO:001923310.020
cell cycle g1 s phase transitionGO:004484310.019
regulation of signal transductionGO:00099662250.019
multicellular organism growthGO:003526440.019
regulation of metabolic processGO:00192223590.019
amino acid transportGO:000686520.019
meiotic cell cycle processGO:190304630.019
exocytosisGO:000688710.019
wnt signaling pathwayGO:0016055800.019
invagination involved in gastrulation with mouth forming secondGO:005510910.019
small molecule metabolic processGO:0044281770.019
regulation of metal ion transportGO:001095940.019
cellular macromolecule metabolic processGO:00442603910.019
regulation of signalingGO:00230512350.019
axonogenesisGO:00074091520.018
regulation of membrane repolarizationGO:006030610.018
monovalent inorganic cation transportGO:0015672420.018
smooth muscle contractionGO:000693920.018
muscle organ developmentGO:00075171010.018
Worm
embryo development ending in birth or egg hatchingGO:00097922710.018
regulation of multicellular organism growthGO:004001440.018
response to topologically incorrect proteinGO:003596620.018
response to drugGO:004249330.018
regulation of nitrogen compound metabolic processGO:00511712510.018
regulation of nucleoside metabolic processGO:000911820.018
cellular localizationGO:0051641970.018
mesenchymal cell differentiationGO:0048762870.018
regulation of cellular amine metabolic processGO:003323800.017
oxoacid metabolic processGO:0043436310.017
cell migrationGO:00164772370.017
regulation of cellular biosynthetic processGO:00313262450.017
amine metabolic processGO:000930820.017
calcium ion transport into cytosolGO:006040230.017
positive regulation of striated muscle tissue developmentGO:004584410.017
multi organism processGO:00517041340.017
Worm
actin filament based processGO:0030029640.017
Zebrafish Mouse
heterocycle biosynthetic processGO:00181302150.017
cellular amine metabolic processGO:004410620.017
adherens junction organizationGO:003433240.017
regulation of cytoplasmic transportGO:190364940.017
nucleic acid templated transcriptionGO:00976591810.017
positive regulation of cellular component biogenesisGO:004408930.017
regulation of ion transmembrane transporter activityGO:003241220.017
gene expressionGO:00104672520.017
cellular ketone metabolic processGO:0042180110.017
biosynthetic processGO:00090582940.017
neurological system processGO:0050877620.017
locomotor rhythmGO:004547530.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
organic acid catabolic processGO:001605430.017
cell fate specificationGO:0001708680.016
Mouse
gtp catabolic processGO:000618420.016
neuron projection morphogenesisGO:00488121610.016
negative regulation of cellular processGO:00485232830.016
small molecule catabolic processGO:004428230.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of cell differentiationGO:00455951420.016
cellular response to oxygen levelsGO:007145310.016
muscle contractionGO:0006936180.016
Mouse Worm
cellular lipid catabolic processGO:004424230.016
positive regulation of muscle organ developmentGO:004863610.016
macromolecule biosynthetic processGO:00090592270.016
regulation of purine nucleotide catabolic processGO:003312120.016
chordate embryonic developmentGO:00430092710.016
mitotic cell cycle embryonicGO:004544820.015
mesenchyme developmentGO:00604851270.015
aromatic compound biosynthetic processGO:00194382170.015
localization of cellGO:00516742440.015
protein localization to nucleusGO:003450430.015
regulation of anatomical structure morphogenesisGO:00226031300.015
nucleic acid metabolic processGO:00903042440.015
negative regulation of response to stimulusGO:00485851040.015
cytosolic calcium ion transportGO:006040130.015
rna transportGO:005065820.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of transporter activityGO:003240920.015
photoreceptor cell fate commitmentGO:004655210.015
apoptotic processGO:00069151160.015
fatty acid catabolic processGO:000906210.015
blood vessel morphogenesisGO:00485142160.014
neuron developmentGO:00486662620.014
vacuolar transportGO:000703420.014
regulation of blood pressureGO:000821710.014
regulation of gene expressionGO:00104682650.014
response to hexoseGO:000974630.014
rna metabolic processGO:00160702190.014
regulation of synaptic plasticityGO:004816710.014
proteolysis involved in cellular protein catabolic processGO:005160330.014
nucleoside monophosphate catabolic processGO:000912540.014
cellular response to hypoxiaGO:007145610.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
cellular macromolecule biosynthetic processGO:00346452240.014
regulation of transcription dna templatedGO:00063552130.014
synaptic vesicle transportGO:004848910.014
ion homeostasisGO:0050801410.014
cellular response to chemical stimulusGO:00708871570.014
regulation of dendrite morphogenesisGO:004881430.014
cell morphogenesis involved in differentiationGO:00009041950.014
regulation of cellular metabolic processGO:00313233200.014
regulation of macromolecule metabolic processGO:00602553170.014
negative regulation of map kinase activityGO:004340720.014
endocardium morphogenesisGO:000316040.014
multicellular organismal signalingGO:0035637220.014
nucleic acid transportGO:005065720.014
cellular amino acid metabolic processGO:000652070.014
regulation of protein catabolic processGO:004217610.014
transcription dna templatedGO:00063511810.014
actomyosin structure organizationGO:0031032530.014
Zebrafish Mouse
negative regulation of signalingGO:0023057960.014
proteasomal protein catabolic processGO:001049820.014
convergent extension involved in gastrulationGO:0060027710.014
spermatid differentiationGO:004851520.014
negative regulation of cell communicationGO:0010648960.013
cellular protein catabolic processGO:004425740.013
positive regulation of cytoskeleton organizationGO:005149530.013
rna biosynthetic processGO:00327741810.013
carboxylic acid metabolic processGO:0019752220.013
meiotic chromosome segregationGO:004513230.013
growthGO:00400071740.013
intracellular signal transductionGO:0035556850.013
regionalizationGO:00030022740.013
synaptic vesicle localizationGO:009747910.013
regulation of stem cell differentiationGO:200073640.013
negative regulation of protein serine threonine kinase activityGO:007190120.013
nuclear transportGO:005116940.013
actin mediated cell contractionGO:007025210.013
sulfur compound transportGO:007234830.013
positive regulation of nucleotide catabolic processGO:003081310.013
cardiac chamber formationGO:000320740.013
purine nucleoside monophosphate catabolic processGO:000912840.013
protein importGO:001703830.013
response to amineGO:001407510.013
cell deathGO:00082191210.013
regulation of primary metabolic processGO:00800903110.013
regulation of bindingGO:005109830.013
striated muscle contractionGO:0006941120.013
Mouse
cellular response to starvationGO:000926710.013
digestive tract developmentGO:00485652650.013
response to carbohydrateGO:000974330.013
axon developmentGO:00615641660.013
eye morphogenesisGO:00485921440.013
regulation of protein transportGO:005122330.013
posterior lateral line neuromast developmentGO:0048919200.013
regulation of neurological system processGO:003164420.013
regulation of protein ubiquitinationGO:003139630.013
nuclear importGO:005117030.013
protein polymerizationGO:005125840.013
mitochondrion organizationGO:000700540.013
development of primary female sexual characteristicsGO:004654540.013
modification dependent macromolecule catabolic processGO:004363230.012
cellular response to extracellular stimulusGO:003166820.012
protein homooligomerizationGO:005126030.012
cell projection assemblyGO:0030031640.012
cellular component disassemblyGO:002241110.012
regulation of cell activationGO:005086510.012
detection of external stimulusGO:0009581240.012
cortical actin cytoskeleton organizationGO:003086610.012
positive regulation of i kappab kinase nf kappab signalingGO:004312330.012
positive regulation of neural precursor cell proliferationGO:200017910.012
establishment of synaptic vesicle localizationGO:009748010.012
regulation of cellular amino acid metabolic processGO:000652100.012
negative regulation of catabolic processGO:000989530.012
response to monosaccharideGO:003428430.012
negative regulation of biological processGO:00485193040.012
negative regulation of protein kinase activityGO:000646940.012
neuromast developmentGO:0048884460.012
dna templated transcription initiationGO:000635210.012
locomotory behaviorGO:0007626340.012
sensory organ developmentGO:00074233930.012
cellular response to topologically incorrect proteinGO:003596720.012
regulation of biosynthetic processGO:00098892500.012
developmental growthGO:00485891660.012
sensory organ morphogenesisGO:00905962000.012
regulation of skeletal muscle tissue developmentGO:004864140.012
protein targeting to nucleusGO:004474430.012
regulation of establishment of planar polarityGO:009017540.012
negative regulation of gliogenesisGO:001401410.012
pronephros morphogenesisGO:0072114140.012
negative regulation of macromolecule metabolic processGO:0010605760.012
gland developmentGO:00487321430.012
peptide transportGO:001583310.012
detection of mechanical stimulus involved in sensory perception of touchGO:005097620.012
embryonic skeletal joint developmentGO:007249830.012
regulation of protein polymerizationGO:003227120.012
eye developmentGO:00016542770.012
female gonad developmentGO:000858540.012
regulation of neurotransmitter transportGO:005158810.012
pharyngeal muscle developmentGO:004328240.012
phosphate containing compound metabolic processGO:00067961080.012
regulation of organelle assemblyGO:190211540.012
cardiac conduction system developmentGO:000316110.012
stem cell differentiationGO:00488631170.012
cell motilityGO:00488702440.012
regulation of macromolecule biosynthetic processGO:00105562250.011
skeletal muscle organ developmentGO:0060538780.011
organonitrogen compound metabolic processGO:1901564740.011
neuronal stem cell maintenanceGO:009715020.011
regulation of erk1 and erk2 cascadeGO:007037240.011
negative regulation of metabolic processGO:0009892860.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
negative regulation of protein phosphorylationGO:000193340.011
central nervous system neuron differentiationGO:0021953740.011
regulation of localizationGO:00328791040.011
specification of organ positionGO:001015930.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
neural crest formationGO:0014029140.011
nucleobase containing compound transportGO:001593120.011
regulation of membrane potentialGO:0042391230.011
response to unfolded proteinGO:000698620.011
regulation of cellular component organizationGO:0051128860.011
leukocyte proliferationGO:007066110.011
cranial nerve developmentGO:0021545420.011
regulation of rna metabolic processGO:00512522240.011
action potentialGO:0001508190.011
regulation of protein localization to nucleusGO:190018020.011
phosphorus metabolic processGO:00067931090.011
pericardium morphogenesisGO:000334410.011
hormone secretionGO:004687920.011
secondary metabolic processGO:001974830.011
regulation of wound healingGO:006104120.011
multi organism cellular processGO:004476420.011
lipid oxidationGO:003444010.011
positive regulation of nucleoside metabolic processGO:004597910.011
post embryonic morphogenesisGO:000988640.011
regulation of apoptotic processGO:0042981980.011
mrna transportGO:005102820.011
dorsal ventral pattern formationGO:00099531250.011
actin cytoskeleton organizationGO:0030036630.011
Zebrafish Mouse
sequestering of metal ionGO:005123830.011
g1 s transition of mitotic cell cycleGO:000008210.011
regulation of cell substrate adhesionGO:001081010.011
skeletal muscle tissue developmentGO:0007519670.011
proepicardium developmentGO:000334240.011
regulation of neurotransmitter secretionGO:004692810.011
circadian sleep wake cycle processGO:002241020.011
guanosine containing compound catabolic processGO:190106920.011
positive regulation of stem cell proliferationGO:200064810.011
membrane repolarizationGO:008600920.011
somatic stem cell maintenanceGO:003501910.011
cellular response to external stimulusGO:007149620.011
glial cell migrationGO:000834730.011
cell matrix adhesionGO:000716040.011
regulation of mesenchymal cell proliferationGO:001046410.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
phagocytosisGO:000690930.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
negative regulation of protein complex assemblyGO:003133310.010
establishment of localization in cellGO:0051649770.010
somite developmentGO:0061053960.010
guanosine containing compound metabolic processGO:190106840.010
spermatid developmentGO:000728620.010
branching morphogenesis of a nerveGO:004875540.010
mitotic cytokinesisGO:000028130.010
immune system processGO:00023762410.010
response to glucoseGO:000974930.010
olfactory lobe developmentGO:002198840.010
negative regulation of reproductive processGO:200024230.010
translational initiationGO:000641330.010
pigmentationGO:0043473850.010
regulation of peptidyl tyrosine phosphorylationGO:005073010.010
cellular carbohydrate metabolic processGO:004426240.010
positive regulation of cellular amine metabolic processGO:003324000.010
positive regulation of muscle tissue developmentGO:190186310.010
interspecies interaction between organismsGO:004441940.010
positive regulation of heart contractionGO:004582320.010
Zebrafish
maternal determination of anterior posterior axis embryoGO:000835840.010
cardiac atrium morphogenesisGO:000320920.010
autophagyGO:000691440.010
axon guidanceGO:0007411860.010
i kappab kinase nf kappab signalingGO:000724940.010
morphogenesis of an epithelial foldGO:006057110.010
epithelial to mesenchymal transitionGO:0001837210.010
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.010
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.010
regulation of heart rateGO:000202750.010
positive regulation of cytokine productionGO:000181920.010
intracellular mrna localizationGO:000829810.010
somitogenesisGO:0001756870.010
regulation of jak stat cascadeGO:004642530.010
regulation of neuronal synaptic plasticityGO:004816810.010
centrosome organizationGO:005129710.010

myl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.165
musculoskeletal system diseaseDOID:1700.165
muscle tissue diseaseDOID:6600.165
intrinsic cardiomyopathyDOID:006003600.165
disease of anatomical entityDOID:700.165
cardiomyopathyDOID:005070000.165
heart diseaseDOID:11400.165
muscular diseaseDOID:008000000.165
hypertrophic cardiomyopathyDOID:1198400.165
myopathyDOID:42300.165
nervous system diseaseDOID:86300.029
disease of metabolismDOID:001466700.014
inherited metabolic disorderDOID:65500.013
eye and adnexa diseaseDOID:149200.011
sensory system diseaseDOID:005015500.011