Danio rerio

0 known processes

lgi2b

leucine-rich repeat LGI family, member 2b

lgi2b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.062
cognitionGO:005089010.062
maintenance of locationGO:005123540.054
phagocytosisGO:000690930.052
larval developmentGO:000216420.044
multicellular organism growthGO:003526440.042
embryonic organ developmentGO:00485683810.041
generation of neuronsGO:00486993850.041
response to external stimulusGO:00096052640.041
tube morphogenesisGO:00352393490.039
morphogenesis of an epitheliumGO:00020093330.037
cell projection morphogenesisGO:00488582440.037
neuron developmentGO:00486662620.036
response to stressGO:00069502630.036
cell projection organizationGO:00300302840.035
amine metabolic processGO:000930820.035
axonogenesisGO:00074091520.035
cell part morphogenesisGO:00329902460.034
regulation of multicellular organism growthGO:004001440.034
embryonic organ morphogenesisGO:00485622740.034
signal transductionGO:00071654550.033
chordate embryonic developmentGO:00430092710.033
central nervous system developmentGO:00074173870.032
Zebrafish
cellular amine metabolic processGO:004410620.032
positive regulation of transportGO:005105020.032
guanosine containing compound metabolic processGO:190106840.031
cellular protein catabolic processGO:004425740.031
sensory organ developmentGO:00074233930.030
cell morphogenesis involved in differentiationGO:00009041950.030
gtp metabolic processGO:004603940.030
regulation of cellular amino acid metabolic processGO:000652100.030
regulation of bindingGO:005109830.030
chemosensory behaviorGO:000763510.029
response to chemicalGO:00422213200.029
digestive tract developmentGO:00485652650.029
regulation of cellular amine metabolic processGO:003323800.029
proteolysis involved in cellular protein catabolic processGO:005160330.029
cell morphogenesisGO:00009022890.029
regulation of macromolecule metabolic processGO:00602553170.028
regulation of metal ion transportGO:001095940.028
guanosine containing compound catabolic processGO:190106920.028
cellular macromolecule metabolic processGO:00442603910.028
cellular component morphogenesisGO:00329893360.028
locomotionGO:00400113130.028
cellular component movementGO:00069283350.028
positive regulation of cellular amino acid metabolic processGO:004576400.027
autophagyGO:000691440.027
inorganic ion transmembrane transportGO:0098660570.027
neuron differentiationGO:00301823530.027
vasculature developmentGO:00019442780.027
cell migrationGO:00164772370.027
heart developmentGO:00075073130.027
regulation of multicellular organismal processGO:00512392770.026
regulation of cell communicationGO:00106462320.026
gtp catabolic processGO:000618420.026
digestive system developmentGO:00551232890.026
axon developmentGO:00615641660.026
establishment of localizationGO:00512342440.025
embryonic skeletal system developmentGO:0048706970.025
regulation of establishment of protein localizationGO:007020140.025
adult behaviorGO:003053420.025
cation transportGO:0006812810.025
positive regulation of catabolic processGO:000989640.025
nitrogen compound metabolic processGO:00068073190.025
inorganic cation transmembrane transportGO:0098662500.024
cell motilityGO:00488702440.024
positive regulation of cellular amine metabolic processGO:003324000.024
digestive tract morphogenesisGO:00485462310.024
regulation of metabolic processGO:00192223590.024
immune system processGO:00023762410.024
ion transportGO:00068111140.023
neuron projection developmentGO:00311751800.023
gastrulationGO:00073692080.023
regulation of cellular ketone metabolic processGO:001056570.023
response to carbohydrateGO:000974330.023
organic cyclic compound metabolic processGO:19013603010.023
eye developmentGO:00016542770.023
head developmentGO:00603223030.023
Zebrafish
endocrine processGO:005088620.023
regulation of calcium ion transportGO:005192420.023
regulation of response to stimulusGO:00485832690.023
regulation of multicellular organismal developmentGO:20000262230.023
positive regulation of cellular catabolic processGO:003133130.023
transmembrane transportGO:00550851200.023
regulation of biological qualityGO:00650082630.023
Zebrafish
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.023
ion transmembrane transportGO:0034220910.022
regulation of nitrogen compound metabolic processGO:00511712510.022
positive regulation of cellular component biogenesisGO:004408930.022
protein metabolic processGO:00195381830.022
regulation of protein transportGO:005122330.022
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.022
membrane invaginationGO:001032410.022
organonitrogen compound metabolic processGO:1901564740.022
modification dependent protein catabolic processGO:001994130.022
cation transmembrane transportGO:0098655650.022
skeletal system developmentGO:00015011810.022
cell surface receptor signaling pathwayGO:00071663250.022
cellular response to external stimulusGO:007149620.022
phagocytosis engulfmentGO:000691110.022
single organism metabolic processGO:00447102170.022
single organism localizationGO:19025782250.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.021
regulation of reproductive processGO:200024140.021
neurological system processGO:0050877620.021
Zebrafish
neuron neuron synaptic transmissionGO:000727010.021
metal ion transportGO:0030001580.021
positive regulation of cell cycleGO:004578730.021
ubiquitin dependent protein catabolic processGO:000651130.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.020
brain developmentGO:00074202930.020
Zebrafish
cellular amide metabolic processGO:004360340.020
extrinsic apoptotic signaling pathwayGO:009719130.020
positive regulation of biological processGO:00485182530.020
cellular ketone metabolic processGO:0042180110.020
heterocycle metabolic processGO:00464832900.020
gene expressionGO:00104672520.020
stem cell proliferationGO:007208940.020
regulation of synaptic plasticityGO:004816710.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
negative regulation of biological processGO:00485193040.020
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
response to uvGO:000941130.019
regulation of signalingGO:00230512350.019
synaptic growth at neuromuscular junctionGO:005112420.019
regulation of cytoplasmic transportGO:190364940.019
regulation of programmed cell deathGO:00430671010.019
regulation of dendrite developmentGO:005077330.019
mitochondrion organizationGO:000700540.019
sensory perception of chemical stimulusGO:000760630.019
regulation of reactive oxygen species metabolic processGO:200037720.019
negative regulation of protein kinase activityGO:000646940.019
proteasomal protein catabolic processGO:001049820.019
localization of cellGO:00516742440.019
single fertilizationGO:000733830.019
neuron projection morphogenesisGO:00488121610.018
establishment of protein localization to organelleGO:007259440.018
modification dependent macromolecule catabolic processGO:004363230.018
rna metabolic processGO:00160702190.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.018
nuclear transportGO:005116940.018
regulation of cell activationGO:005086510.018
cytokinesisGO:000091030.018
response to glucocorticoidGO:005138410.018
response to drugGO:004249330.018
cellular amino acid metabolic processGO:000652070.018
determination of bilateral symmetryGO:00098552040.018
growthGO:00400071740.018
response to woundingGO:00096111160.018
fertilizationGO:000956630.018
protein localization to nucleusGO:003450430.018
centrosome organizationGO:005129710.018
peptide metabolic processGO:000651810.018
cellular aromatic compound metabolic processGO:00067252950.017
positive regulation of cellular processGO:00485222010.017
camera type eye developmentGO:00430102220.017
response to corticosteroidGO:003196010.017
negative regulation of protein phosphorylationGO:000193340.017
system processGO:00030081850.017
Zebrafish
single organism transportGO:00447652060.017
regulation of cell deathGO:00109411030.017
immune system developmentGO:00025201910.017
regulation of cellular metabolic processGO:00313233200.017
regulation of synapse organizationGO:005080730.017
determination of left right symmetryGO:00073681790.017
embryonic skeletal system morphogenesisGO:0048704930.017
skeletal system morphogenesisGO:00487051020.017
regionalizationGO:00030022740.017
transportGO:00068102200.017
carboxylic acid metabolic processGO:0019752220.016
sensory perception of painGO:001923310.016
regulation of gene expressionGO:00104682650.016
cellular response to extracellular stimulusGO:003166820.016
blood vessel morphogenesisGO:00485142160.016
smooth muscle contractionGO:000693920.016
oxoacid metabolic processGO:0043436310.016
specification of symmetryGO:00097992040.016
multi organism processGO:00517041340.016
leukocyte proliferationGO:007066110.016
response to monosaccharideGO:003428430.016
protein localization to plasma membraneGO:007265910.016
mechanosensory behaviorGO:000763820.016
regulation of synapse assemblyGO:005196330.016
regulation of signal transductionGO:00099662250.016
muscle organ developmentGO:00075171010.016
regulation of cell shapeGO:000836010.016
cell substrate adhesionGO:003158940.016
regulation of primary metabolic processGO:00800903110.016
muscle structure developmentGO:00610611960.016
exocytosisGO:000688710.016
antimicrobial humoral responseGO:001973020.016
regulation of cytokine productionGO:000181730.016
organic substance biosynthetic processGO:19015762890.016
regulation of dendrite morphogenesisGO:004881430.015
regulation of blood pressureGO:000821710.015
negative regulation of cellular processGO:00485232830.015
positive regulation of cytokine productionGO:000181920.015
protein targeting to nucleusGO:004474430.015
cellular protein metabolic processGO:00442671290.015
neuromuscular synaptic transmissionGO:000727420.015
positive regulation of immune effector processGO:000269930.015
protein secretionGO:000930610.015
stem cell maintenanceGO:001982740.015
anterior posterior pattern specificationGO:00099521520.015
cellular component biogenesisGO:00440851780.015
production of molecular mediator of immune responseGO:000244020.015
homeostatic processGO:00425921420.015
hemopoiesisGO:00300971830.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
response to other organismGO:0051707970.015
protein dephosphorylationGO:000647030.015
regulation of circadian rhythmGO:004275240.015
small molecule metabolic processGO:0044281770.015
multicellular organismal response to stressGO:003355520.015
response to nutrientGO:000758430.015
regulation of purine nucleotide catabolic processGO:003312120.015
behaviorGO:0007610740.015
Zebrafish
regenerationGO:0031099910.015
blood vessel developmentGO:00015682460.015
cellular component assemblyGO:00226071700.015
transcription dna templatedGO:00063511810.015
meiotic cell cycle processGO:190304630.015
programmed cell deathGO:00125011190.015
phosphorus metabolic processGO:00067931090.014
response to hexoseGO:000974630.014
cellular biosynthetic processGO:00442492860.014
b cell activationGO:004211320.014
regulation of protein complex assemblyGO:004325430.014
liver developmentGO:0001889960.014
regulation of autophagyGO:001050630.014
hormone secretionGO:004687920.014
adherens junction organizationGO:003433240.014
regulation of developmental processGO:00507932470.014
phototransductionGO:000760220.014
regulation of localizationGO:00328791040.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
epithelial tube morphogenesisGO:00605621480.014
peptide transportGO:001583310.014
rna localizationGO:000640340.014
regulation of neural precursor cell proliferationGO:200017730.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
female gonad developmentGO:000858540.014
cellular response to chemical stimulusGO:00708871570.014
embryonic heart tube developmentGO:00350501330.014
carbohydrate homeostasisGO:003350010.014
regulation of tube sizeGO:003515020.014
nuclear importGO:005117030.014
positive regulation of cell activationGO:005086710.014
regulation of stem cell proliferationGO:007209120.014
taxisGO:00423301090.014
regulation of ion transmembrane transporter activityGO:003241220.014
negative regulation of kinase activityGO:003367340.014
cellular nitrogen compound metabolic processGO:00346412900.014
response to glucoseGO:000974930.014
organic acid metabolic processGO:0006082310.014
regulation of protein bindingGO:004339330.014
development of primary female sexual characteristicsGO:004654540.014
sensory organ morphogenesisGO:00905962000.014
nucleobase containing compound biosynthetic processGO:00346542050.014
biosynthetic processGO:00090582940.014
meiotic nuclear divisionGO:000712640.014
glucose homeostasisGO:004259310.014
organic cyclic compound biosynthetic processGO:19013622230.013
protein stabilizationGO:005082120.013
neurotransmitter secretionGO:000726920.013
regulation of protein catabolic processGO:004217610.013
positive regulation of secretionGO:005104710.013
positive regulation of protein complex assemblyGO:003133420.013
stem cell divisionGO:001714510.013
positive regulation of leukocyte differentiationGO:190210710.013
cellular response to nutrient levelsGO:003166920.013
regulation of nucleoside metabolic processGO:000911820.013
protein modification processGO:00362111000.013
hepaticobiliary system developmentGO:0061008980.013
transcription from rna polymerase ii promoterGO:0006366800.013
female sex differentiationGO:004666040.013
maternal determination of anterior posterior axis embryoGO:000835840.013
microtubule organizing center organizationGO:003102310.013
heterocycle biosynthetic processGO:00181302150.013
apoptotic processGO:00069151160.013
carbohydrate biosynthetic processGO:001605110.013
macromolecule biosynthetic processGO:00090592270.013
outflow tract morphogenesisGO:000315110.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
cellular protein modification processGO:00064641000.013
neurotransmitter transportGO:000683620.013
regulation of sequestering of calcium ionGO:005128240.013
positive regulation of dna metabolic processGO:005105410.013
lymphocyte proliferationGO:004665110.013
phosphate containing compound metabolic processGO:00067961080.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
regulation of jak stat cascadeGO:004642530.013
nucleocytoplasmic transportGO:000691340.013
cell deathGO:00082191210.013
hormone transportGO:000991420.013
cellular nitrogen compound biosynthetic processGO:00442712180.013
erk1 and erk2 cascadeGO:007037140.013
negative regulation of catabolic processGO:000989530.013
peptidyl serine modificationGO:001820920.013
nuclear migrationGO:000709730.013
positive regulation of nucleoside metabolic processGO:004597910.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
deathGO:00162651210.013
sequestering of calcium ionGO:005120830.013
regulation of apoptotic processGO:0042981980.012
negative regulation of map kinase activityGO:004340720.012
nucleic acid metabolic processGO:00903042440.012
chemotaxisGO:00069351040.012
organism emergence from protective structureGO:007168440.012
compound eye developmentGO:004874920.012
eye morphogenesisGO:00485921440.012
cellular response to starvationGO:000926710.012
regulation of inflammatory responseGO:005072720.012
wound healingGO:0042060900.012
lipid storageGO:001991510.012
macromolecule modificationGO:00434121110.012
regulation of cellular biosynthetic processGO:00313262450.012
embryo development ending in birth or egg hatchingGO:00097922710.012
response to biotic stimulusGO:0009607970.012
regulation of protein ubiquitinationGO:003139630.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of cell projection assemblyGO:006049140.012
protein importGO:001703830.012
developmental growth involved in morphogenesisGO:0060560860.012
golgi vesicle transportGO:004819330.012
peptidyl threonine phosphorylationGO:001810710.012
neuron projection guidanceGO:0097485860.012
regulation of erk1 and erk2 cascadeGO:007037240.012
peptidyl threonine modificationGO:001821010.012
angiogenesisGO:00015251580.012
positive regulation of cytoskeleton organizationGO:005149530.012
endosomal transportGO:001619720.012
positive regulation of gtpase activityGO:004354710.012
response to alkaloidGO:004327920.012
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.012
nucleic acid templated transcriptionGO:00976591810.012
regulation of blood vessel sizeGO:005088020.012
protein import into nucleusGO:000660630.012
somite developmentGO:0061053960.012
response to external biotic stimulusGO:0043207970.012
calcium ion transport into cytosolGO:006040230.011
intracellular signal transductionGO:0035556850.011
protein heterooligomerizationGO:005129110.011
neuroblast proliferationGO:000740520.011
regulation of cell differentiationGO:00455951420.011
retina development in camera type eyeGO:00600411460.011
convergent extensionGO:00600261180.011
mononuclear cell proliferationGO:003294310.011
embryonic heart tube morphogenesisGO:00031431080.011
gland developmentGO:00487321430.011
positive regulation of map kinase activityGO:004340630.011
mitochondrial transportGO:000683920.011
olfactory lobe developmentGO:002198840.011
spermatid differentiationGO:004851520.011
germ line stem cell maintenanceGO:003071820.011
lateral inhibitionGO:004633110.011
central nervous system neuron differentiationGO:0021953740.011
cellular component disassemblyGO:002241110.011
water homeostasisGO:003010440.011
nucleobase containing compound metabolic processGO:00061392740.011
energy reserve metabolic processGO:000611220.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
negative regulation of protein transportGO:005122430.011
regulation of protein targetingGO:190353320.011
regulation of gtp catabolic processGO:003312420.011
protein polymerizationGO:005125840.011
oocyte anterior posterior axis specificationGO:000731440.011
aromatic compound biosynthetic processGO:00194382170.011
intracellular mrna localizationGO:000829810.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
regulation of nucleocytoplasmic transportGO:004682220.011
striated muscle tissue developmentGO:00147061100.011
convergent extension involved in gastrulationGO:0060027710.011
axon guidanceGO:0007411860.011
mitotic cell cycle embryonicGO:004544820.011
regulation of production of molecular mediator of immune responseGO:000270010.011
regulation of protein localization to nucleusGO:190018020.011
cell matrix adhesionGO:000716040.011
cellular response to organic substanceGO:00713101050.011
regulation of protein polymerizationGO:003227120.011
organelle fusionGO:004828430.011
cellular macromolecule biosynthetic processGO:00346452240.011
positive regulation of secretion by cellGO:190353210.011
tissue remodelingGO:004877140.011
actin polymerization or depolymerizationGO:000815420.011
positive regulation of cell adhesionGO:004578510.011
regulation of endocrine processGO:004406020.011
regulation of neuron differentiationGO:0045664560.011
cilium organizationGO:0044782710.011
negative regulation of cytoplasmic transportGO:190365020.011
secondary metabolic processGO:001974830.011
negative regulation of multicellular organismal processGO:0051241690.011
segmentationGO:0035282970.011
regulation of gtpase activityGO:004308720.010
cellular response to molecule of bacterial originGO:007121930.010
regulation of nucleotide catabolic processGO:003081120.010
regulation of protein import into nucleusGO:004230620.010
positive regulation of purine nucleotide catabolic processGO:003312310.010
forebrain developmentGO:0030900960.010
regulation of response to biotic stimulusGO:000283120.010
thermosensory behaviorGO:004004010.010
cytosolic calcium ion transportGO:006040130.010
regulation of nucleobase containing compound metabolic processGO:00192192500.010
cytoplasm organizationGO:000702840.010
sequestering of metal ionGO:005123830.010
positive regulation of cell killingGO:003134320.010
cellular response to reactive oxygen speciesGO:003461420.010
interspecies interaction between organismsGO:004441940.010
single organism organelle organizationGO:19025891990.010
ameboidal type cell migrationGO:00016671430.010
dicarboxylic acid transportGO:000683510.010
negative regulation of defense responseGO:003134820.010
positive regulation of nucleotide catabolic processGO:003081310.010
negative regulation of mapk cascadeGO:004340940.010
negative regulation of nucleocytoplasmic transportGO:004682320.010
developmental cell growthGO:0048588520.010
lateral line system developmentGO:0048925760.010
regulation of systemic arterial blood pressureGO:000307310.010
tyrosine phosphorylation of stat proteinGO:000726010.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
regulation of mrna processingGO:005068430.010

lgi2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
immune system diseaseDOID:291400.020
nervous system diseaseDOID:86300.015
disease of metabolismDOID:001466700.013
musculoskeletal system diseaseDOID:1700.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
cardiovascular system diseaseDOID:128700.012
organ system cancerDOID:005068600.010