Danio rerio

51 known processes

tm4sf4

transmembrane 4 L six family member 4

(Aliases: zgc:92479)

tm4sf4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to external stimulusGO:00096052640.498
response to drugGO:004249330.433
response to monosaccharideGO:003428430.407
response to carbohydrateGO:000974330.340
digestive system developmentGO:00551232890.323
immune system processGO:00023762410.312
response to glucoseGO:000974930.310
hormone transportGO:000991420.289
lipid catabolic processGO:001604240.284
response to nutrientGO:000758430.273
glucose homeostasisGO:004259310.262
regulation of hormone secretionGO:004688320.256
hematopoietic or lymphoid organ developmentGO:00485341910.246
carbohydrate homeostasisGO:003350010.231
specification of symmetryGO:00097992040.231
agingGO:000756820.225
regulation of response to stimulusGO:00485832690.224
hormone secretionGO:004687920.222
regulation of multicellular organismal processGO:00512392770.218
enzyme linked receptor protein signaling pathwayGO:00071671060.215
response to hexoseGO:000974630.208
positive regulation of transportGO:005105020.193
diterpenoid metabolic processGO:0016101150.193
chordate embryonic developmentGO:00430092710.183
cellular carbohydrate metabolic processGO:004426240.179
localization of cellGO:00516742440.175
peptide transportGO:001583310.174
retinoic acid receptor signaling pathwayGO:0048384160.163
cellular response to external stimulusGO:007149620.159
regulation of cell communicationGO:00106462320.151
heart developmentGO:00075073130.150
regulation of signal transductionGO:00099662250.147
response to vitamin b3GO:003355220.145
gastrulationGO:00073692080.142
response to alkaloidGO:004327920.141
foregut morphogenesisGO:000744040.133
neural tube developmentGO:0021915620.131
nucleic acid templated transcriptionGO:00976591810.128
response to corticosteroidGO:003196010.121
neural tube patterningGO:0021532330.114
immune system developmentGO:00025201910.112
cell motilityGO:00488702440.109
regulation of localizationGO:00328791040.108
positive regulation of cellular processGO:00485222010.106
regulation of bindingGO:005109830.105
cellular response to starvationGO:000926710.104
vasculature developmentGO:00019442780.103
regulation of macromolecule biosynthetic processGO:00105562250.102
cell migrationGO:00164772370.099
i kappab kinase nf kappab signalingGO:000724940.098
cellular response to chemical stimulusGO:00708871570.098
multicellular organism growthGO:003526440.098
carboxylic acid metabolic processGO:0019752220.095
morphogenesis of an epitheliumGO:00020093330.094
negative regulation of signalingGO:0023057960.093
response to amineGO:001407510.093
regulation of transcription dna templatedGO:00063552130.092
cellular response to biotic stimulusGO:007121630.092
response to organic substanceGO:00100331530.089
carbohydrate metabolic processGO:0005975120.088
organic substance transportGO:0071702580.088
cellular response to organic substanceGO:00713101050.087
determination of bilateral symmetryGO:00098552040.086
skeletal system developmentGO:00015011810.086
response to endogenous stimulusGO:0009719830.084
endocrine system developmentGO:0035270650.083
cellular response to extracellular stimulusGO:003166820.082
single organism metabolic processGO:00447102170.081
response to hormoneGO:0009725480.080
regulation of cellular macromolecule biosynthetic processGO:20001122220.079
sensory organ developmentGO:00074233930.079
regulation of biological qualityGO:00650082630.077
single organism localizationGO:19025782250.077
intestinal absorptionGO:005089220.076
oxoacid metabolic processGO:0043436310.076
regulation of rna metabolic processGO:00512522240.076
response to biotic stimulusGO:0009607970.075
oxidation reduction processGO:0055114410.074
negative regulation of biological processGO:00485193040.074
nucleobase containing compound biosynthetic processGO:00346542050.073
regulation of molecular functionGO:0065009700.072
embryonic heart tube morphogenesisGO:00031431080.070
digestive tract developmentGO:00485652650.069
regulation of peptidyl tyrosine phosphorylationGO:005073010.069
response to chemicalGO:00422213200.069
multi organism processGO:00517041340.068
protein metabolic processGO:00195381830.068
protein targeting to nucleusGO:004474430.067
hormone biosynthetic processGO:004244630.067
regulation of transportGO:0051049450.067
response to oxygen containing compoundGO:1901700550.067
lipid storageGO:001991510.066
regulation of cytokine productionGO:000181730.066
single organism transportGO:00447652060.063
ameboidal type cell migrationGO:00016671430.062
biosynthetic processGO:00090582940.062
positive regulation of secretionGO:005104710.062
renal system process involved in regulation of systemic arterial blood pressureGO:000307110.062
heart loopingGO:0001947940.062
response to lipidGO:0033993600.062
regulation of multicellular organism growthGO:004001440.062
nuclear transportGO:005116940.061
epithelial cell differentiationGO:00308551160.061
cellular response to oxygen containing compoundGO:1901701200.061
negative regulation of cellular processGO:00485232830.061
angiogenesisGO:00015251580.060
blood vessel developmentGO:00015682460.060
embryonic organ developmentGO:00485683810.060
positive regulation of cellular carbohydrate metabolic processGO:001067610.059
positive regulation of cell activationGO:005086710.058
segment polarity determinationGO:000736710.058
amide transportGO:0042886120.058
zymogen activationGO:003163830.056
regulation of cell activationGO:005086510.056
cellular component movementGO:00069283350.056
determination of left right symmetryGO:00073681790.056
endocrine pancreas developmentGO:0031018270.056
lipid oxidationGO:003444010.055
diterpenoid biosynthetic processGO:001610270.055
positive regulation of lipid metabolic processGO:004583410.054
rna metabolic processGO:00160702190.054
regulation of cellular carbohydrate metabolic processGO:001067540.054
positive regulation of secretion by cellGO:190353210.054
regulation of i kappab kinase nf kappab signalingGO:004312240.054
positive regulation of cellular component biogenesisGO:004408930.053
regulation of signalingGO:00230512350.053
response to acid chemicalGO:0001101170.053
response to nutrient levelsGO:0031667100.053
system processGO:00030081850.052
cellular biosynthetic processGO:00442492860.051
wound healingGO:0042060900.051
Rat
cellular component morphogenesisGO:00329893360.051
amine metabolic processGO:000930820.051
ion transportGO:00068111140.050
regulation of protein localization to nucleusGO:190018020.050
liver developmentGO:0001889960.050
regulation of neuron migrationGO:200122220.050
acylglycerol homeostasisGO:005509020.049
response to nitrogen compoundGO:1901698190.049
disruption of cells of other organismGO:004436410.049
deathGO:00162651210.048
cellular hormone metabolic processGO:0034754190.048
protein import into nucleusGO:000660630.048
regulation of wound healingGO:006104120.048
determination of heart left right asymmetryGO:00613711170.048
epithelial cell developmentGO:0002064420.048
gene expressionGO:00104672520.047
locomotionGO:00400113130.047
regulation of protein import into nucleusGO:004230620.047
nuclear importGO:005117030.047
endocrine processGO:005088620.046
response to glucocorticoidGO:005138410.046
homeostatic processGO:00425921420.045
response to vitaminGO:003327330.045
symbiosis encompassing mutualism through parasitismGO:004440340.045
regulation of gene expressionGO:00104682650.045
intracellular signal transductionGO:0035556850.045
dicarboxylic acid transportGO:000683510.044
rna biosynthetic processGO:00327741810.044
lipid biosynthetic processGO:0008610220.044
urogenital system developmentGO:0001655970.044
regulation of metabolic processGO:00192223590.044
otic vesicle developmentGO:0071599420.044
pectoral fin developmentGO:0033339500.043
positive regulation of biological processGO:00485182530.043
kupffer s vesicle developmentGO:0070121500.043
regulation of rna biosynthetic processGO:20011412130.043
regulation of programmed cell deathGO:00430671010.042
transportGO:00068102200.042
cellular response to hormone stimulusGO:0032870390.042
polyol metabolic processGO:001975110.042
positive regulation of signal transductionGO:0009967560.042
lipid digestionGO:004424130.041
xenobiotic metabolic processGO:000680540.041
regulation of primary metabolic processGO:00800903110.041
organic cyclic compound metabolic processGO:19013603010.041
adherens junction organizationGO:003433240.041
fat soluble vitamin metabolic processGO:000677540.040
cardiac cell fate commitmentGO:006091110.040
establishment of localizationGO:00512342440.040
epithelial tube morphogenesisGO:00605621480.040
regulation of neurogenesisGO:0050767870.040
cellular response to drugGO:003569010.040
negative regulation of signal transductionGO:0009968940.039
response to organic cyclic compoundGO:0014070510.039
regulation of blood coagulationGO:003019310.039
regulation of carbohydrate metabolic processGO:000610940.039
gland developmentGO:00487321430.039
regulation of nucleic acid templated transcriptionGO:19035062130.038
maintenance of locationGO:005123540.038
regulation of reproductive processGO:200024140.038
hindbrain developmentGO:0030902910.038
hemopoiesisGO:00300971830.038
response to extracellular stimulusGO:0009991100.038
alcohol biosynthetic processGO:004616520.038
regulation of nitrogen compound metabolic processGO:00511712510.037
b cell activationGO:004211320.037
tube morphogenesisGO:00352393490.037
response to bacteriumGO:0009617580.036
cellular response to endogenous stimulusGO:0071495680.036
positive regulation of rna metabolic processGO:0051254590.036
regulation of hormone levelsGO:0010817210.036
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.036
cell surface receptor signaling pathwayGO:00071663250.036
regulation of protein catabolic processGO:004217610.036
single organism carbohydrate metabolic processGO:0044723120.036
regulation of tube sizeGO:003515020.035
insulin like growth factor receptor signaling pathwayGO:004800940.035
cartilage developmentGO:0051216960.035
cellular ketone metabolic processGO:0042180110.035
phagocytosisGO:000690930.035
epithelial cell migrationGO:0010631250.035
nitrogen compound metabolic processGO:00068073190.035
periodic partitioningGO:000736510.035
negative regulation of macromolecule metabolic processGO:0010605760.035
hormone metabolic processGO:0042445190.035
interspecies interaction between organismsGO:004441940.035
negative regulation of macromolecule biosynthetic processGO:0010558480.035
regulation of stem cell differentiationGO:200073640.034
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.034
regulation of lipid catabolic processGO:005099420.034
isoprenoid biosynthetic processGO:000829970.034
protein localization to nucleusGO:003450430.034
nitrogen compound transportGO:0071705230.034
pyruvate metabolic processGO:000609010.033
single organism nuclear importGO:190259330.033
lipid homeostasisGO:005508830.033
response to stressGO:00069502630.033
Rat
signal transductionGO:00071654550.033
cell deathGO:00082191210.033
hepaticobiliary system developmentGO:0061008980.033
response to other organismGO:0051707970.033
organic acid metabolic processGO:0006082310.033
anterior posterior pattern specificationGO:00099521520.032
regulation of cellular metabolic processGO:00313233200.032
regulation of protein transportGO:005122330.032
regulation of protein targetingGO:190353320.032
mesenchyme developmentGO:00604851270.032
regulation of vascular endothelial growth factor receptor signaling pathwayGO:003094780.032
heterocycle biosynthetic processGO:00181302150.032
regulation of protein complex assemblyGO:004325430.031
cellular macromolecule biosynthetic processGO:00346452240.031
post embryonic morphogenesisGO:000988640.031
organelle assemblyGO:00709251100.031
cell projection morphogenesisGO:00488582440.031
response to mercury ionGO:004668910.031
transcription dna templatedGO:00063511810.031
establishment of protein localization to organelleGO:007259440.031
transcription from rna polymerase ii promoterGO:0006366800.031
small molecule biosynthetic processGO:0044283160.030
cellular lipid metabolic processGO:0044255360.030
regulation of transcription from rna polymerase ii promoterGO:00063571140.030
polyol biosynthetic processGO:004617310.030
steroid metabolic processGO:000820270.030
negative regulation of cell communicationGO:0010648960.030
negative regulation of feeding behaviorGO:200025220.030
embryonic heart tube developmentGO:00350501330.030
renal system developmentGO:0072001940.030
regulation of apoptotic processGO:0042981980.029
exocrine pancreas developmentGO:0031017280.029
positive regulation of multicellular organismal processGO:0051240520.029
negative regulation of cell deathGO:0060548600.029
nucleocytoplasmic transportGO:000691340.029
regulation of cell deathGO:00109411030.029
appendage developmentGO:0048736800.029
regulation of cellular amino acid metabolic processGO:000652100.029
embryonic organ morphogenesisGO:00485622740.029
steroid biosynthetic processGO:000669450.029
regulation of organ growthGO:004662030.029
defense response to gram negative bacteriumGO:005082980.029
lipid metabolic processGO:0006629520.029
androgen metabolic processGO:000820920.029
tyrosine phosphorylation of stat proteinGO:000726010.028
smooth muscle contractionGO:000693920.028
protein importGO:001703830.028
terpenoid metabolic processGO:0006721150.028
positive regulation of i kappab kinase nf kappab signalingGO:004312330.028
protein heterooligomerizationGO:005129110.028
monocyte differentiationGO:003022420.028
regulation of heart growthGO:006042020.028
negative regulation of cellular biosynthetic processGO:0031327550.028
regulation of establishment of protein localizationGO:007020140.028
sensory organ morphogenesisGO:00905962000.028
regulation of cellular ketone metabolic processGO:001056570.028
positive regulation of cytokine productionGO:000181920.028
regulation of intracellular protein transportGO:003315730.027
response to steroid hormoneGO:0048545350.027
inner ear developmentGO:00488391260.027
secondary metabolic processGO:001974830.027
immune effector processGO:0002252230.027
regulation of cellular biosynthetic processGO:00313262450.027
cellular amine metabolic processGO:004410620.026
positive regulation of programmed cell deathGO:0043068290.026
cellular aromatic compound metabolic processGO:00067252950.026
defense response to bacteriumGO:0042742220.026
regulation of metal ion transportGO:001095940.026
response to amphetamineGO:000197510.026
response to external biotic stimulusGO:0043207970.026
fin developmentGO:0033333770.026
regulation of blood vessel sizeGO:005088020.026
regulation of steroid hormone secretionGO:200083110.026
endothelial cell migrationGO:0043542190.025
embryonic digestive tract morphogenesisGO:004855730.025
regulation of establishment of planar polarityGO:009017540.025
cellular protein metabolic processGO:00442671290.025
production of molecular mediator of immune responseGO:000244020.025
regulation of immune system processGO:0002682340.025
cellular nitrogen compound biosynthetic processGO:00442712180.025
larval developmentGO:000216420.025
negative regulation of apoptotic processGO:0043066550.025
cellular response to acid chemicalGO:007122980.025
killing of cells in other organism involved in symbiotic interactionGO:005188310.025
positive regulation of response to stimulusGO:0048584800.025
regulation of cellular amine metabolic processGO:003323800.025
energy reserve metabolic processGO:000611220.025
positive regulation of epithelial cell migrationGO:001063420.024
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.024
heterocycle metabolic processGO:00464832900.024
pigmentationGO:0043473850.024
carbohydrate biosynthetic processGO:001605110.024
somite developmentGO:0061053960.024
regulation of catalytic activityGO:0050790550.024
positive regulation of signalingGO:0023056560.024
organic substance biosynthetic processGO:19015762890.024
regulation of macromolecule metabolic processGO:00602553170.024
regulation of production of molecular mediator of immune responseGO:000270010.024
b cell differentiationGO:003018310.023
retinoid metabolic processGO:0001523150.023
embryonic foregut morphogenesisGO:004861710.023
negative regulation of multicellular organismal processGO:0051241690.023
cell part morphogenesisGO:00329902460.023
regulation of cellular component movementGO:0051270550.023
cell morphogenesisGO:00009022890.023
leukocyte differentiationGO:0002521250.022
regulation of muscle contractionGO:000693730.022
positive regulation of gene expressionGO:0010628710.022
post embryonic foregut morphogenesisGO:004861830.022
response to abiotic stimulusGO:00096281220.022
fat soluble vitamin biosynthetic processGO:004236220.022
extrinsic apoptotic signaling pathwayGO:009719130.022
epithelial cell morphogenesisGO:000338220.022
positive regulation of muscle tissue developmentGO:190186310.022
positive regulation of leukocyte differentiationGO:190210710.022
negative regulation of protein phosphorylationGO:000193340.022
negative regulation of kinase activityGO:003367340.022
positive regulation of cellular amine metabolic processGO:003324000.022
growthGO:00400071740.022
Rat
post embryonic organ developmentGO:004856940.022
monoamine transportGO:001584410.022
cellular protein modification processGO:00064641000.022
small molecule metabolic processGO:0044281770.022
isoprenoid metabolic processGO:0006720150.021
neuromast developmentGO:0048884460.021
cellular amino acid metabolic processGO:000652070.021
reactive oxygen species biosynthetic processGO:190340910.021
regulation of nucleocytoplasmic transportGO:004682220.021
regulation of protein bindingGO:004339330.021
response to immobilization stressGO:003590210.021
positive regulation of neuron migrationGO:200122420.021
cellular response to peptide hormone stimulusGO:007137550.021
positive regulation of macromolecule metabolic processGO:0010604930.021
eye morphogenesisGO:00485921440.021
negative regulation of metabolic processGO:0009892860.021
regulation of tyrosine phosphorylation of stat proteinGO:004250910.021
organic cyclic compound biosynthetic processGO:19013622230.021
intestinal epithelial cell differentiationGO:006057530.021
response to starvationGO:004259450.021
leukocyte chemotaxisGO:0030595120.021
membrane hyperpolarizationGO:006008110.020
regulation of collagen metabolic processGO:001071220.020
positive regulation of cellular catabolic processGO:003133130.020
regulation of jun kinase activityGO:004350630.020
amino acid transportGO:000686520.020
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.020
protein secretionGO:000930610.020
regulation of cell migrationGO:0030334400.020
negative regulation of cellular protein metabolic processGO:0032269160.020
cell cell signalingGO:0007267520.020
response to organonitrogen compoundGO:0010243120.020
response to inorganic substanceGO:0010035380.020
aromatic compound biosynthetic processGO:00194382170.019
sensory system developmentGO:0048880760.019
regulation of cell differentiationGO:00455951420.019
negative regulation of protein serine threonine kinase activityGO:007190120.019
tissue regenerationGO:0042246740.019
Rat
cerebellar granular layer developmentGO:002168130.019
lateral line system developmentGO:0048925760.019
membrane invaginationGO:001032410.019
centrosome organizationGO:005129710.019
osteoclast differentiationGO:003031610.019
embryo development ending in birth or egg hatchingGO:00097922710.019
positive regulation of immune system processGO:0002684170.019
type b pancreatic cell developmentGO:000332340.019
macromolecule biosynthetic processGO:00090592270.019
ear developmentGO:00435831270.018
embryonic neurocranium morphogenesisGO:0048702150.018
granulocyte migrationGO:0097530110.018
granulocyte chemotaxisGO:0071621110.018
organic hydroxy compound transportGO:0015850140.018
regulation of ion transportGO:0043269220.018
cellular aldehyde metabolic processGO:000608140.018
developmental growthGO:00485891660.018
Rat
regulation of system processGO:0044057400.018
positive regulation of cell communicationGO:0010647560.018
tissue migrationGO:0090130370.017
cellular macromolecule metabolic processGO:00442603910.017
negative regulation of dna replicationGO:000815620.017
germ line stem cell maintenanceGO:003071820.017
cell junction maintenanceGO:003433120.017
nucleic acid metabolic processGO:00903042440.017
stem cell developmentGO:0048864820.017
bmp signaling pathwayGO:0030509520.017
cerebellar granular layer formationGO:002168430.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
regulation of cytoplasmic transportGO:190364940.017
plasma membrane repairGO:000177820.017
autophagyGO:000691440.017
cell substrate adhesionGO:003158940.017
regulation of sodium ion transportGO:000202820.016
negative regulation of biosynthetic processGO:0009890550.016
negative regulation of nucleobase containing compound metabolic processGO:0045934590.016
nik nf kappab signalingGO:003806110.016
positive regulation of cytoskeleton organizationGO:005149530.016
cell proliferationGO:0008283800.016
endothelial cell developmentGO:0001885120.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
sensory perception of smellGO:000760820.016
myelin assemblyGO:003228810.016
neuron differentiationGO:00301823530.016
negative regulation of cellular metabolic processGO:0031324770.016
fin morphogenesisGO:0033334530.016
negative regulation of gene expressionGO:0010629650.016
blood vessel morphogenesisGO:00485142160.016
response to methanolGO:003398640.016
connective tissue developmentGO:0061448990.016
embryonic digestive tract developmentGO:004856640.016
regulation of cardiac muscle contractionGO:005511720.015
negative regulation of dna metabolic processGO:005105340.015
vitamin biosynthetic processGO:000911020.015
peptide metabolic processGO:000651810.015
regionalizationGO:00030022740.015
regulation of response to extracellular stimulusGO:003210410.015
positive regulation of developmental processGO:0051094500.015
organonitrogen compound metabolic processGO:1901564740.015
monocarboxylic acid metabolic processGO:0032787170.015
golgi vesicle transportGO:004819330.015
digestive tract morphogenesisGO:00485462310.015
positive regulation of carbohydrate metabolic processGO:004591310.015
head developmentGO:00603223030.015
positive regulation of jak stat cascadeGO:004642720.015
regulation of reactive oxygen species metabolic processGO:200037720.015
single organism organelle organizationGO:19025891990.015
regulation of coagulationGO:005081820.015
ventricular cardiac muscle tissue developmentGO:000322930.015
negative regulation of response to stimulusGO:00485851040.015
regulation of glucose importGO:004632410.014
skeletal system morphogenesisGO:00487051020.014
regulation of multicellular organismal developmentGO:20000262230.014
regulation of response to stressGO:0080134360.014
regulation of dna replicationGO:000627530.014
regulation of endocrine processGO:004406020.014
glucocorticoid metabolic processGO:000821120.014
columnar cuboidal epithelial cell differentiationGO:0002065380.014
positive regulation of catabolic processGO:000989640.014
stem cell differentiationGO:00488631170.014
response to woundingGO:00096111160.014
Rat
signal transduction downstream of smoothenedGO:000722710.014
cell migration involved in heart formationGO:0060974100.014
negative regulation of growthGO:0045926100.014
antimicrobial humoral responseGO:001973020.014
cellular response to organic cyclic compoundGO:0071407380.014
regulation of growthGO:0040008420.014
negative regulation of epithelial cell proliferationGO:005068010.014
vitamin metabolic processGO:0006766110.014
regulation of sequence specific dna binding transcription factor activityGO:005109090.014
appendage morphogenesisGO:0035107560.014
calcium ion importGO:007050940.014
brain developmentGO:00074202930.014
cellular nitrogen compound metabolic processGO:00346412900.014
kidney developmentGO:0001822920.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.014
regulation of transcription from rna polymerase iii promoterGO:000635910.014

tm4sf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.098
maturity onset diabetes of the youngDOID:005052400.054
type 2 diabetes mellitusDOID:935200.039
glucose metabolism diseaseDOID:419400.039
acquired metabolic diseaseDOID:006015800.039
carbohydrate metabolism diseaseDOID:005001300.039
diabetes mellitusDOID:935100.039
disease of metabolismDOID:001466700.039
disease of cellular proliferationDOID:1456600.034
organ system cancerDOID:005068600.034
cancerDOID:16200.034
endocrine system diseaseDOID:2800.020
artery diseaseDOID:005082800.015
vascular diseaseDOID:17800.015
cardiovascular system diseaseDOID:128700.015