Danio rerio

15 known processes

crh

corticotropin releasing hormone

(Aliases: crf,zgc:101864)

crh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
monoamine transportGO:001584410.920
Rat
catechol containing compound metabolic processGO:000971220.702
regulation of nucleobase containing compound metabolic processGO:00192192500.670
Rat
catecholamine metabolic processGO:000658420.648
response to amineGO:001407510.630
eye developmentGO:00016542770.557
dopamine biosynthetic processGO:004241620.554
response to amphetamineGO:000197510.534
regulation of primary metabolic processGO:00800903110.501
Rat
nucleobase containing compound metabolic processGO:00061392740.482
Rat
regulation of cellular biosynthetic processGO:00313262450.472
Rat
adult behaviorGO:003053420.447
nitrogen compound metabolic processGO:00068073190.435
Rat
steroid hormone mediated signaling pathwayGO:004340190.420
neuron differentiationGO:00301823530.408
catechol containing compound biosynthetic processGO:000971320.380
response to abiotic stimulusGO:00096281220.330
Rat
response to immobilization stressGO:003590210.265
macromolecule biosynthetic processGO:00090592270.265
axon extensionGO:0048675450.262
regulation of oxidative stress induced cell deathGO:190320120.261
neuron neuron synaptic transmissionGO:000727010.259
Rat
dopamine metabolic processGO:004241720.258
cellular nitrogen compound metabolic processGO:00346412900.244
Rat
negative regulation of biological processGO:00485193040.238
Rat
negative regulation of protein kinase activityGO:000646940.226
circadian sleep wake cycleGO:004274520.214
taxisGO:00423301090.209
regulation of macromolecule metabolic processGO:00602553170.208
Rat
organic cyclic compound metabolic processGO:19013603010.208
Mouse Rat
phosphorus metabolic processGO:00067931090.202
Rat
regulation of cyclic nucleotide biosynthetic processGO:0030802150.187
Rat
response to chemicalGO:00422213200.186
Rat
response to stressGO:00069502630.177
response to foodGO:003209410.172
heterocycle biosynthetic processGO:00181302150.170
Rat
heterocycle metabolic processGO:00464832900.154
Rat
regulation of extrinsic apoptotic signaling pathwayGO:200123630.151
circadian sleep wake cycle processGO:002241020.146
phosphorylationGO:0016310690.146
Rat
negative regulation of cellular processGO:00485232830.144
Rat
cellular nitrogen compound biosynthetic processGO:00442712180.143
Rat
nitrogen compound transportGO:0071705230.140
Rat
regulation of molecular functionGO:0065009700.136
Rat
retina development in camera type eyeGO:00600411460.133
response to extracellular stimulusGO:0009991100.132
transcription from rna polymerase ii promoterGO:0006366800.132
regulation of nitrogen compound metabolic processGO:00511712510.129
Rat
central nervous system neuron differentiationGO:0021953740.128
regulation of neurogenesisGO:0050767870.127
organic substance biosynthetic processGO:19015762890.126
Mouse Rat
regulation of catalytic activityGO:0050790550.124
regulation of cellular macromolecule biosynthetic processGO:20001122220.118
positive regulation of inflammatory responseGO:005072910.114
regionalizationGO:00030022740.112
phagocytosisGO:000690930.111
cognitionGO:005089010.110
Rat
regulation of neurological system processGO:003164420.110
regulation of metabolic processGO:00192223590.107
Rat
nucleic acid metabolic processGO:00903042440.106
regulation of locomotionGO:0040012550.104
transcription dna templatedGO:00063511810.099
sensory organ developmentGO:00074233930.099
rna metabolic processGO:00160702190.098
regulation of postsynaptic membrane potentialGO:006007810.097
single organism metabolic processGO:00447102170.092
Mouse Rat
response to external stimulusGO:00096052640.091
regulation of biosynthetic processGO:00098892500.091
Rat
positive regulation of biological processGO:00485182530.088
Rat
system processGO:00030081850.088
Rat
regulation of cell communicationGO:00106462320.088
Rat
cellular biosynthetic processGO:00442492860.082
Rat
primary amino compound metabolic processGO:190116010.081
sensory organ morphogenesisGO:00905962000.080
negative regulation of macromolecule metabolic processGO:0010605760.079
Rat
lymph vessel developmentGO:0001945270.078
cell migrationGO:00164772370.078
response to alkaloidGO:004327920.078
Rat
amine metabolic processGO:000930820.078
regulation of developmental processGO:00507932470.077
single organism behaviorGO:0044708240.077
Mouse Rat
generation of neuronsGO:00486993850.077
negative regulation of phosphate metabolic processGO:0045936130.076
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.075
gene expressionGO:00104672520.075
Rat
nucleobase containing compound biosynthetic processGO:00346542050.074
Rat
organic cyclic compound biosynthetic processGO:19013622230.074
Mouse Rat
head developmentGO:00603223030.073
Rat
negative regulation of metabolic processGO:0009892860.073
Rat
regulation of multicellular organismal developmentGO:20000262230.072
regulation of biological qualityGO:00650082630.071
Rat
positive regulation of catalytic activityGO:0043085250.069
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.069
cellular macromolecule metabolic processGO:00442603910.068
Rat
organic hydroxy compound biosynthetic processGO:190161760.067
cell death in response to oxidative stressGO:003647320.066
gabaergic neuron differentiationGO:009715420.065
cell motilityGO:00488702440.062
positive regulation of cellular component biogenesisGO:004408930.062
neuron projection extensionGO:1990138450.062
positive regulation of cell deathGO:0010942290.060
Rat
locomotionGO:00400113130.059
phagocytosis engulfmentGO:000691110.059
negative regulation of biosynthetic processGO:0009890550.058
regulation of cellular response to oxidative stressGO:190040720.058
negative regulation of dna metabolic processGO:005105340.058
centrosome organizationGO:005129710.057
regulation of cyclase activityGO:0031279120.056
regulation of signal transductionGO:00099662250.056
Rat
thermosensory behaviorGO:004004010.055
intracellular receptor signaling pathwayGO:0030522300.055
camera type eye developmentGO:00430102220.054
membrane hyperpolarizationGO:006008110.053
central nervous system developmentGO:00074173870.053
Rat
regulation of cellular metabolic processGO:00313233200.052
Rat
regulation of response to stimulusGO:00485832690.051
Rat
sleepGO:003043110.050
serotonin biosynthetic processGO:004242710.049
negative regulation of locomotionGO:0040013180.049
cellular response to oxygen levelsGO:007145310.049
carbohydrate derivative metabolic processGO:1901135610.049
Rat
cellular response to external stimulusGO:007149620.049
regulation of circadian rhythmGO:004275240.048
regulation of purine nucleotide metabolic processGO:1900542170.048
Rat
neuron projection developmentGO:00311751800.048
regulation of calcium ion transportGO:005192420.048
Rat
developmental maturationGO:0021700340.047
regulation of lipase activityGO:006019120.047
developmental cell growthGO:0048588520.046
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.046
regulation of circadian sleep wake cycleGO:004274910.045
regulation of cellular amine metabolic processGO:003323800.044
single organism transportGO:00447652060.044
Rat
cell morphogenesisGO:00009022890.044
rna biosynthetic processGO:00327741810.044
negative regulation of dna replicationGO:000815620.044
negative regulation of kinase activityGO:003367340.042
cellular amine metabolic processGO:004410620.041
negative regulation of protein phosphorylationGO:000193340.040
response to steroid hormoneGO:0048545350.040
Rat
localization of cellGO:00516742440.039
g protein coupled receptor signaling pathwayGO:0007186740.039
biosynthetic processGO:00090582940.039
Mouse Rat
agingGO:000756820.038
negative regulation of cellular metabolic processGO:0031324770.038
microtubule organizing center organizationGO:003102310.038
positive regulation of response to external stimulusGO:003210390.038
negative regulation of epithelial cell proliferationGO:005068010.038
multicellular organismal response to stressGO:003355520.038
Rat
embryo development ending in birth or egg hatchingGO:00097922710.038
cellular pigmentationGO:0033059300.038
apoptotic processGO:00069151160.038
Rat
negative regulation of camp biosynthetic processGO:003081870.037
regulation of camp biosynthetic processGO:003081790.037
Rat
regulation of synapse organizationGO:005080730.037
lipid catabolic processGO:001604240.037
catecholamine biosynthetic processGO:004242320.036
regulation of dna replicationGO:000627530.035
intracellular estrogen receptor signaling pathwayGO:003052030.035
regulation of chronic inflammatory responseGO:000267610.034
embryonic organ developmentGO:00485683810.034
response to inorganic substanceGO:0010035380.034
nucleic acid templated transcriptionGO:00976591810.034
circadian sleep wake cycle sleepGO:005080210.033
cellular localizationGO:0051641970.033
dopaminergic neuron differentiationGO:0071542140.033
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.033
regulation of dendrite developmentGO:005077330.033
carbohydrate derivative biosynthetic processGO:1901137430.033
Rat
regulation of phosphate metabolic processGO:0019220430.033
Rat
regulation of signalingGO:00230512350.033
Rat
response to estrogenGO:0043627270.032
Rat
lipid metabolic processGO:0006629520.032
Mouse Rat
positive regulation of developmental processGO:0051094500.032
negative regulation of programmed cell deathGO:0043069580.032
organic hydroxy compound metabolic processGO:1901615160.032
negative regulation of phosphorus metabolic processGO:0010563130.031
regulation of blood vessel sizeGO:005088020.031
cellular aromatic compound metabolic processGO:00067252950.031
Rat
regulation of hormone secretionGO:004688320.031
Rat
maintenance of locationGO:005123540.030
response to light stimulusGO:0009416460.030
regulation of nucleic acid templated transcriptionGO:19035062130.030
cell surface receptor signaling pathwayGO:00071663250.030
Rat
positive regulation of nitrogen compound metabolic processGO:0051173690.030
Rat
response to temperature stimulusGO:0009266150.030
establishment of synaptic vesicle localizationGO:009748010.029
multicellular organismal water homeostasisGO:005089110.029
positive regulation of cellular biosynthetic processGO:0031328680.029
Rat
posterior lateral line developmentGO:0048916380.029
mitochondrion organizationGO:000700540.029
developmental growthGO:00485891660.029
response to endogenous stimulusGO:0009719830.029
Rat
regulation of cellular protein metabolic processGO:0032268520.028
Rat
neuromuscular synaptic transmissionGO:000727420.028
neurotransmitter secretionGO:000726920.028
organonitrogen compound biosynthetic processGO:1901566470.028
Rat
protein modification processGO:00362111000.028
Rat
regulation of transcription from rna polymerase ii promoterGO:00063571140.027
cellular response to extracellular stimulusGO:003166820.027
neuron projection morphogenesisGO:00488121610.027
small molecule metabolic processGO:0044281770.026
Rat
negative regulation of nucleobase containing compound metabolic processGO:0045934590.026
organonitrogen compound metabolic processGO:1901564740.026
Rat
organelle transport along microtubuleGO:007238410.026
female sex differentiationGO:004666040.026
hormone transportGO:000991420.026
Rat
cell cell signalingGO:0007267520.025
Rat
lateral inhibitionGO:004633110.025
urea transportGO:0015840110.025
regulation of anatomical structure morphogenesisGO:00226031300.025
signal transductionGO:00071654550.025
Rat
cellular response to steroid hormone stimulusGO:0071383310.025
Rat
regulation of nucleotide metabolic processGO:0006140170.024
Rat
single organism biosynthetic processGO:0044711710.024
Mouse Rat
cellular component movementGO:00069283350.024
regulation of dna metabolic processGO:0051052110.024
response to amino acidGO:004320020.024
dorsal ventral pattern formationGO:00099531250.024
response to oxidative stressGO:0006979110.024
response to oxygen containing compoundGO:1901700550.024
Rat
positive regulation of phosphorus metabolic processGO:0010562210.024
Rat
synapsisGO:000712910.024
circadian behaviorGO:004851250.023
locomotor rhythmGO:004547530.023
regulation of gtp catabolic processGO:003312420.023
retrograde axon cargo transportGO:000809010.023
neutrophil chemotaxisGO:0030593100.023
regulation of nervous system developmentGO:0051960900.023
serotonin metabolic processGO:004242810.022
regulation of phosphorus metabolic processGO:0051174430.022
Rat
behaviorGO:0007610740.022
Mouse Rat
vesicle localizationGO:0051648270.021
phenol containing compound biosynthetic processGO:004618940.021
inner ear developmentGO:00488391260.021
aromatic compound biosynthetic processGO:00194382170.021
Rat
positive regulation of cellular metabolic processGO:0031325940.021
Rat
purine ribonucleotide metabolic processGO:0009150270.020
Rat
response to nutrientGO:000758430.020
phosphate containing compound metabolic processGO:00067961080.020
Rat
response to hypoxiaGO:0001666250.020
mechanosensory behaviorGO:000763820.020
positive regulation of synapse assemblyGO:005196510.020
cerebellar granular layer formationGO:002168430.020
postsynaptic membrane organizationGO:000194130.020
positive regulation of axon guidanceGO:190266910.020
regulation of circadian sleep wake cycle sleepGO:004518710.019
regulation of phosphorylationGO:0042325260.019
Rat
positive regulation of macromolecule metabolic processGO:0010604930.019
Rat
axon extension involved in axon guidanceGO:0048846100.019
multi organism processGO:00517041340.019
lateral line developmentGO:0048882660.019
transportGO:00068102200.019
Rat
regulation of glutamate receptor signaling pathwayGO:190044910.019
Rat
centrosome cycleGO:000709810.019
response to cortisolGO:005141410.019
regulation of n methyl d aspartate selective glutamate receptor activityGO:200031010.019
Rat
organophosphate metabolic processGO:0019637370.019
Rat
positive regulation of transportGO:005105020.019
Rat
positive regulation of metabolic processGO:00098931080.019
Rat
central nervous system neuron axonogenesisGO:0021955180.019
response to organic substanceGO:00100331530.019
Rat
cellular protein metabolic processGO:00442671290.018
Rat
macromolecule modificationGO:00434121110.018
Rat
calcium mediated signalingGO:001972220.018
vesicle transport along microtubuleGO:004749610.018
regulation of reproductive processGO:200024140.018
regulation of macromolecule biosynthetic processGO:00105562250.018
positive regulation of gene expressionGO:0010628710.018
Rat
multicellular organism growthGO:003526440.018
regulation of behaviorGO:0050795240.018
Rat
glycolipid biosynthetic processGO:000924710.018
larval developmentGO:000216420.018
synaptic transmissionGO:0007268350.018
Rat
regulation of rna metabolic processGO:00512522240.018
cellular response to lipidGO:0071396390.018
Rat
enzyme linked receptor protein signaling pathwayGO:00071671060.018
centrosome localizationGO:005164210.018
oxidation reduction processGO:0055114410.017
lymphangiogenesisGO:0001946250.017
synaptic vesicle localizationGO:009747910.017
renal absorptionGO:007029310.017
cellular response to toxic substanceGO:009723710.017
negative regulation of neutrophil chemotaxisGO:009002430.017
positive regulation of cellular processGO:00485222010.017
Rat
dicarboxylic acid transportGO:000683510.017
response to carbohydrateGO:000974330.017
Rat
negative regulation of gliogenesisGO:001401410.017
positive regulation of cell cycleGO:004578730.017
interspecies interaction between organismsGO:004441940.017
positive regulation of biosynthetic processGO:0009891680.016
Rat
negative regulation of axon guidanceGO:190266810.016
hindbrain developmentGO:0030902910.016
positive regulation of neuron apoptotic processGO:004352510.016
spinal cord developmentGO:0021510460.016
cellular response to decreased oxygen levelsGO:003629410.016
chemical homeostasisGO:0048878490.016
Rat
regulation of inflammatory responseGO:005072720.016
peptide transportGO:001583310.016
Rat
cell part morphogenesisGO:00329902460.016
glucose homeostasisGO:004259310.016
Rat
cellular response to hypoxiaGO:007145610.016
phenol containing compound metabolic processGO:001895850.016
response to metal ionGO:0010038340.016
muscle cell migrationGO:001481240.016
regulation of cellular component organizationGO:0051128860.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:000718750.015
pronuclear migrationGO:003504610.015
regulation of cell differentiationGO:00455951420.015
regulation of inhibitory postsynaptic membrane potentialGO:006008010.015
sphingolipid biosynthetic processGO:003014820.015
reactive nitrogen species metabolic processGO:200105700.015
lipid storageGO:001991510.015
regulation of response to external stimulusGO:0032101310.015
synaptic vesicle transportGO:004848910.015
guanosine containing compound metabolic processGO:190106840.015
regulation of gene expressionGO:00104682650.015
Rat
amino acid transportGO:000686520.015
cellular macromolecule biosynthetic processGO:00346452240.014
peptidyl serine phosphorylationGO:001810510.014
regulation of protein phosphorylationGO:0001932180.014
Rat
cellular response to stressGO:0033554620.014
response to woundingGO:00096111160.014
programmed cell deathGO:00125011190.014
Rat
oxidative demethylationGO:007098910.014
response to dexamethasoneGO:007154810.014
Rat
indole containing compound biosynthetic processGO:004243510.014
cerebellar cortex formationGO:002169750.014
development of primary female sexual characteristicsGO:004654540.014
regulation of cell migrationGO:0030334400.014
regulation of lyase activityGO:0051339120.014
neuron deathGO:0070997210.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
forebrain neuron developmentGO:002188470.014
organic hydroxy compound transportGO:0015850140.014
Rat
response to vitamin b3GO:003355220.014
negative regulation of oxidative stress induced cell deathGO:190320220.014
rhythmic behaviorGO:000762250.013
cerebellar granule cell differentiationGO:002170730.013
nitric oxide biosynthetic processGO:000680920.013
dna metabolic processGO:0006259270.013
cell deathGO:00082191210.013
Rat
fatty acid transportGO:001590810.013
protein metabolic processGO:00195381830.013
Rat
organelle localizationGO:0051640490.013
negative regulation of intracellular signal transductionGO:1902532220.013
axonogenesisGO:00074091520.013
response to radiationGO:0009314510.013
positive regulation of cell growthGO:003030750.013
camp metabolic processGO:0046058110.013
Rat
establishment of localizationGO:00512342440.013
Rat
protein phosphorylationGO:0006468470.013
Rat
regulation of neuron projection developmentGO:0010975400.013
regulation of reactive oxygen species metabolic processGO:200037720.013
guanosine containing compound catabolic processGO:190106920.013
eye photoreceptor cell differentiationGO:0001754450.013
adenohypophysis developmentGO:0021984150.013
negative regulation of catalytic activityGO:0043086210.013
regulation of transcription dna templatedGO:00063552130.013
cell projection organizationGO:00300302840.012
cellular amino acid metabolic processGO:000652070.012
regulation of neurotransmitter secretionGO:004692810.012
tyrosine phosphorylation of stat proteinGO:000726010.012
indole containing compound metabolic processGO:004243020.012
membrane invaginationGO:001032410.012
cell projection morphogenesisGO:00488582440.012
female gonad developmentGO:000858540.012
positive regulation of apoptotic processGO:0043065290.012
positive regulation of molecular functionGO:0044093330.012
response to vitaminGO:003327330.012
small molecule catabolic processGO:004428230.012
growthGO:00400071740.012
positive regulation of multi organism processGO:004390230.012
regulation of neuron differentiationGO:0045664560.012
neuron migrationGO:0001764220.012
chemosensory behaviorGO:000763510.012
regulation of cellular ketone metabolic processGO:001056570.012
positive regulation of programmed cell deathGO:0043068290.012
cellular response to hormone stimulusGO:0032870390.012
Rat
regulation of synaptic transmissionGO:005080440.012
Rat
cellular component morphogenesisGO:00329893360.012
homeostatic processGO:00425921420.012
Rat
positive regulation of cell projection organizationGO:003134690.012
response to oxygen levelsGO:0070482250.012
positive regulation of neuron differentiationGO:0045666120.012
neuron developmentGO:00486662620.012
spindle assemblyGO:005122520.012
camera type eye photoreceptor cell differentiationGO:0060219190.012
regulation of dna templated transcription in response to stressGO:004362000.012
forebrain neuron fate commitmentGO:002187710.012
embryonic organ morphogenesisGO:00485622740.011
regulation of tube sizeGO:003515020.011
positive regulation of neuron deathGO:190121610.011
camp biosynthetic processGO:0006171110.011
Rat
eye morphogenesisGO:00485921440.011
lipid biosynthetic processGO:0008610220.011
Mouse
positive regulation of neuron projection developmentGO:001097690.011
dna biosynthetic processGO:007189730.011
apoptotic signaling pathwayGO:0097190230.011
Rat
positive regulation of cytokine productionGO:000181920.011
regulation of camp metabolic processGO:003081490.011
Rat
nucleotide biosynthetic processGO:0009165210.011
Rat
regulation of programmed cell deathGO:00430671010.011
negative regulation of cellular component movementGO:0051271180.011
meiotic nuclear divisionGO:000712640.011
positive regulation of catabolic processGO:000989640.011
olfactory lobe developmentGO:002198840.011
mammillary body developmentGO:002176740.011
positive regulation of rna biosynthetic processGO:1902680570.011
brain developmentGO:00074202930.011
Rat
regulation of fatty acid metabolic processGO:001921710.011
regulation of cyclic nucleotide metabolic processGO:0030799150.011
Rat
axon guidanceGO:0007411860.011
response to nicotineGO:003509420.011
primary amino compound biosynthetic processGO:190116210.010
negative regulation of mapk cascadeGO:004340940.010
auditory receptor cell fate specificationGO:004266720.010
regulation of response to oxidative stressGO:190288220.010
synaptic transmission glycinergicGO:006001210.010
ph reductionGO:004585110.010
epithelial cell differentiationGO:00308551160.010
regulation of neurotransmitter transportGO:005158810.010
neural retina developmentGO:0003407490.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
defense responseGO:0006952470.010
Mouse Rat
synapse organizationGO:0050808210.010
cell type specific apoptotic processGO:0097285220.010
regulation of cellular protein catabolic processGO:190336210.010

crh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.083
synucleinopathyDOID:005089000.071
nervous system diseaseDOID:86300.071
neurodegenerative diseaseDOID:128900.071
central nervous system diseaseDOID:33100.071
parkinson s diseaseDOID:1433000.031
endocrine system diseaseDOID:2800.013
physical disorderDOID:008001500.013
congenital nervous system abnormalityDOID:249000.013
disease of cellular proliferationDOID:1456600.010