Danio rerio

0 known processes

tp53rk

TP53 regulating kinase

(Aliases: MGC110000,fd05d02,zgc:110000,wu:fd05d02)

tp53rk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.102
agingGO:000756820.050
cellular macromolecule metabolic processGO:00442603910.039
establishment of protein localization to organelleGO:007259440.038
nitrogen compound metabolic processGO:00068073190.038
positive regulation of transportGO:005105020.037
mitochondrion organizationGO:000700540.037
cellular nitrogen compound metabolic processGO:00346412900.036
cellular protein catabolic processGO:004425740.035
phagocytosisGO:000690930.035
protein targeting to nucleusGO:004474430.034
proteolysis involved in cellular protein catabolic processGO:005160330.033
amine metabolic processGO:000930820.032
regulation of multicellular organism growthGO:004001440.031
maintenance of locationGO:005123540.031
ubiquitin dependent protein catabolic processGO:000651130.031
signal transductionGO:00071654550.030
negative regulation of protein phosphorylationGO:000193340.030
biosynthetic processGO:00090582940.030
protein importGO:001703830.030
multicellular organism growthGO:003526440.030
protein localization to nucleusGO:003450430.030
membrane fusionGO:006102520.030
organic cyclic compound metabolic processGO:19013603010.029
regulation of establishment of protein localizationGO:007020140.029
single organism nuclear importGO:190259330.029
single organism metabolic processGO:00447102170.029
organelle organizationGO:00069962270.029
modification dependent protein catabolic processGO:001994130.029
nucleocytoplasmic transportGO:000691340.028
regulation of meiotic cell cycleGO:005144510.028
rna localizationGO:000640340.028
autophagyGO:000691440.028
positive regulation of cellular component biogenesisGO:004408930.028
regulation of protein transportGO:005122330.028
organic substance biosynthetic processGO:19015762890.028
regulation of cellular amine metabolic processGO:003323800.028
nuclear importGO:005117030.028
modification dependent macromolecule catabolic processGO:004363230.027
positive regulation of cell cycleGO:004578730.027
protein import into nucleusGO:000660630.027
positive regulation of catabolic processGO:000989640.027
stem cell proliferationGO:007208940.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.027
proteasomal protein catabolic processGO:001049820.027
meiotic nuclear divisionGO:000712640.027
cell surface receptor signaling pathwayGO:00071663250.027
nucleobase containing compound metabolic processGO:00061392740.027
cellular amine metabolic processGO:004410620.026
regulation of cytokine productionGO:000181730.026
cellular biosynthetic processGO:00442492860.026
regulation of metabolic processGO:00192223590.026
regulation of neural precursor cell proliferationGO:200017730.026
regulation of intracellular protein transportGO:003315730.026
regulation of protein import into nucleusGO:004230620.026
single organism membrane fusionGO:004480120.025
positive regulation of cellular catabolic processGO:003133130.025
heterocycle metabolic processGO:00464832900.024
sensory organ developmentGO:00074233930.024
protein acetylationGO:000647320.024
cellular aromatic compound metabolic processGO:00067252950.024
rna metabolic processGO:00160702190.024
cellular component movementGO:00069283350.024
regulation of cytoplasmic transportGO:190364940.024
cell cycle g1 s phase transitionGO:004484310.024
response to drugGO:004249330.024
negative regulation of biological processGO:00485193040.024
generation of neuronsGO:00486993850.024
regulation of protein localization to nucleusGO:190018020.024
oxoacid metabolic processGO:0043436310.024
cell part morphogenesisGO:00329902460.023
cellular component morphogenesisGO:00329893360.023
stem cell maintenanceGO:001982740.023
regulation of nitrogen compound metabolic processGO:00511712510.023
nuclear transportGO:005116940.023
regulation of protein targetingGO:190353320.023
protein metabolic processGO:00195381830.023
peptidyl lysine acetylationGO:001839420.023
aromatic compound biosynthetic processGO:00194382170.023
lipid storageGO:001991510.023
negative regulation of protein kinase activityGO:000646940.023
gtp catabolic processGO:000618420.023
regionalizationGO:00030022740.023
organic acid metabolic processGO:0006082310.023
small molecule metabolic processGO:0044281770.023
organic acid catabolic processGO:001605430.023
regulation of cellular metabolic processGO:00313233200.022
immune system processGO:00023762410.022
response to stressGO:00069502630.022
negative regulation of kinase activityGO:003367340.022
regulation of protein catabolic processGO:004217610.022
gtp metabolic processGO:004603940.022
regulation of cellular amino acid metabolic processGO:000652100.022
negative regulation of mitosisGO:004583930.022
establishment of localizationGO:00512342440.022
gene expressionGO:00104672520.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
internal protein amino acid acetylationGO:000647520.022
regulation of reproductive processGO:200024140.022
organelle fusionGO:004828430.022
regulation of autophagyGO:001050630.021
cognitionGO:005089010.021
organonitrogen compound metabolic processGO:1901564740.021
carboxylic acid metabolic processGO:0019752220.021
cellular ketone metabolic processGO:0042180110.021
central nervous system developmentGO:00074173870.021
regulation of cellular ketone metabolic processGO:001056570.021
atp catabolic processGO:000620040.021
guanosine containing compound metabolic processGO:190106840.021
regulation of nucleocytoplasmic transportGO:004682220.021
regulation of protein complex assemblyGO:004325430.021
internal peptidyl lysine acetylationGO:001839320.021
negative regulation of nuclear divisionGO:005178430.021
regulation of mrna splicing via spliceosomeGO:004802430.021
single organism organelle organizationGO:19025891990.021
cellular response to external stimulusGO:007149620.021
blood vessel developmentGO:00015682460.021
cell morphogenesisGO:00009022890.021
extrinsic apoptotic signaling pathwayGO:009719130.021
purine ribonucleoside monophosphate catabolic processGO:000916940.020
neuron differentiationGO:00301823530.020
head developmentGO:00603223030.020
cellular macromolecule biosynthetic processGO:00346452240.020
meiotic cell cycle processGO:190304630.020
compound eye developmentGO:004874920.020
synaptic growth at neuromuscular junctionGO:005112420.020
vasculature developmentGO:00019442780.020
cellular amino acid metabolic processGO:000652070.020
regulation of metal ion transportGO:001095940.020
cellular nitrogen compound biosynthetic processGO:00442712180.020
response to chemicalGO:00422213200.020
regulation of bindingGO:005109830.020
regulation of macromolecule metabolic processGO:00602553170.020
i kappab kinase nf kappab signalingGO:000724940.020
nucleic acid metabolic processGO:00903042440.019
nucleoside monophosphate catabolic processGO:000912540.019
regulation of mrna processingGO:005068430.019
guanosine containing compound catabolic processGO:190106920.019
cell projection morphogenesisGO:00488582440.019
negative regulation of cellular processGO:00485232830.019
protein acylationGO:004354330.019
regulation of multicellular organismal processGO:00512392770.019
cytokinesisGO:000091030.019
ribonucleoside monophosphate catabolic processGO:000915840.019
locomotionGO:00400113130.019
macromolecule biosynthetic processGO:00090592270.019
regulation of synapse organizationGO:005080730.019
rna biosynthetic processGO:00327741810.019
cellular response to starvationGO:000926710.019
cell projection organizationGO:00300302840.019
single organism localizationGO:19025782250.019
cellular response to extracellular stimulusGO:003166820.018
cellular component assemblyGO:00226071700.018
regulation of cell shapeGO:000836010.018
blood vessel morphogenesisGO:00485142160.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
regulation of primary metabolic processGO:00800903110.018
heterocycle biosynthetic processGO:00181302150.018
regulation of multicellular organismal developmentGO:20000262230.018
organic cyclic compound biosynthetic processGO:19013622230.018
cellular response to nutrient levelsGO:003166920.018
morphogenesis of an epitheliumGO:00020093330.018
regulation of cell activationGO:005086510.018
intracellular mrna localizationGO:000829810.018
regulation of response to stimulusGO:00485832690.018
regulation of protein modification by small protein conjugation or removalGO:190332030.017
nucleobase containing compound biosynthetic processGO:00346542050.017
regulation of nucleoside metabolic processGO:000911820.017
positive regulation of cytokine productionGO:000181920.017
regulation of purine nucleotide catabolic processGO:003312120.017
cellular component biogenesisGO:00440851780.017
cellular protein metabolic processGO:00442671290.017
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.017
embryo development ending in birth or egg hatchingGO:00097922710.017
spermatid developmentGO:000728620.017
transportGO:00068102200.017
cellular component disassemblyGO:002241110.017
g1 s transition of mitotic cell cycleGO:000008210.017
purine nucleoside monophosphate catabolic processGO:000912840.017
immune system developmentGO:00025201910.017
erk1 and erk2 cascadeGO:007037140.017
single organism transportGO:00447652060.017
regulation of erk1 and erk2 cascadeGO:007037240.017
eye developmentGO:00016542770.017
regulation of rna metabolic processGO:00512522240.017
growthGO:00400071740.017
small molecule catabolic processGO:004428230.017
regulation of nucleotide catabolic processGO:003081120.016
positive regulation of protein complex assemblyGO:003133420.016
multi organism cellular processGO:004476420.016
negative regulation of cytoplasmic transportGO:190365020.016
carboxylic acid catabolic processGO:004639530.016
brain developmentGO:00074202930.016
adherens junction organizationGO:003433240.016
mononuclear cell proliferationGO:003294310.016
tube morphogenesisGO:00352393490.016
cellular carbohydrate metabolic processGO:004426240.016
cellular amide metabolic processGO:004360340.016
response to carbohydrateGO:000974330.016
female sex differentiationGO:004666040.016
protein localization to plasma membraneGO:007265910.016
positive regulation of secretionGO:005104710.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
positive regulation of chromatin modificationGO:190331010.016
embryonic organ developmentGO:00485683810.016
negative regulation of catabolic processGO:000989530.016
negative regulation of protein serine threonine kinase activityGO:007190120.016
transcription dna templatedGO:00063511810.016
regulation of gene expressionGO:00104682650.016
protein secretionGO:000930610.016
cellular response to oxygen levelsGO:007145310.016
regulation of synapse assemblyGO:005196330.016
positive regulation of cellular amine metabolic processGO:003324000.015
nucleic acid templated transcriptionGO:00976591810.015
regulation of macromolecule biosynthetic processGO:00105562250.015
regulation of cellular biosynthetic processGO:00313262450.015
exocytosisGO:000688710.015
negative regulation of protein transportGO:005122430.015
production of molecular mediator of immune responseGO:000244020.015
positive regulation of biological processGO:00485182530.015
leukocyte proliferationGO:007066110.015
positive regulation of i kappab kinase nf kappab signalingGO:004312330.015
positive regulation of dna metabolic processGO:005105410.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
locomotor rhythmGO:004547530.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
system processGO:00030081850.015
spermatid differentiationGO:004851520.015
negative regulation of map kinase activityGO:004340720.015
neuron developmentGO:00486662620.015
response to uvGO:000941130.015
phagocytosis engulfmentGO:000691110.015
glucose homeostasisGO:004259310.015
symbiosis encompassing mutualism through parasitismGO:004440340.015
positive regulation of chromosome organizationGO:200125210.015
meiotic chromosome segregationGO:004513230.015
positive regulation of translationGO:004572710.015
lateral inhibitionGO:004633110.014
macromolecule modificationGO:00434121110.014
lipid catabolic processGO:001604240.014
positive regulation of nucleotide catabolic processGO:003081310.014
angiogenesisGO:00015251580.014
adult behaviorGO:003053420.014
cellular response to chemical stimulusGO:00708871570.014
translational initiationGO:000641330.014
regulation of synaptic plasticityGO:004816710.014
positive regulation of nucleoside metabolic processGO:004597910.014
negative regulation of mapk cascadeGO:004340940.014
protein homooligomerizationGO:005126030.014
regulation of developmental processGO:00507932470.014
regulation of stem cell proliferationGO:007209120.014
negative regulation of cytokine productionGO:000181810.014
regulation of cellular protein catabolic processGO:190336210.014
fertilizationGO:000956630.014
regulation of signalingGO:00230512350.014
macromolecular complex disassemblyGO:003298410.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
digestive tract developmentGO:00485652650.014
positive regulation of erk1 and erk2 cascadeGO:007037420.014
maternal determination of anterior posterior axis embryoGO:000835840.014
nucleic acid transportGO:005065720.014
regulation of biological qualityGO:00650082630.014
b cell activationGO:004211320.014
heart developmentGO:00075073130.014
tissue remodelingGO:004877140.014
negative regulation of intracellular transportGO:003238730.014
regulation of nucleobase containing compound metabolic processGO:00192192500.014
lymphocyte proliferationGO:004665110.014
regulation of cell communicationGO:00106462320.014
protein complex disassemblyGO:004324110.014
developmental growthGO:00485891660.014
transcription from rna polymerase ii promoterGO:0006366800.014
female gonad developmentGO:000858540.014
endosomal transportGO:001619720.014
regulation of transcription dna templatedGO:00063552130.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
regulation of gtpase activityGO:004308720.014
interspecies interaction between organismsGO:004441940.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
response to monosaccharideGO:003428430.013
neuroblast proliferationGO:000740520.013
cell migrationGO:00164772370.013
multi organism processGO:00517041340.013
cellular response to biotic stimulusGO:007121630.013
positive regulation of gtp catabolic processGO:003312610.013
centrosome organizationGO:005129710.013
protein heterooligomerizationGO:005129110.013
positive regulation of immune effector processGO:000269930.013
cytoplasm organizationGO:000702840.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
regulation of biosynthetic processGO:00098892500.013
regulation of gtp catabolic processGO:003312420.013
cellular protein modification processGO:00064641000.013
microtubule organizing center organizationGO:003102310.013
positive regulation of histone modificationGO:003105810.013
localization of cellGO:00516742440.013
nucleobase containing compound transportGO:001593120.013
germ line stem cell maintenanceGO:003071820.013
programmed cell deathGO:00125011190.013
positive regulation of cytoskeleton organizationGO:005149530.013
protein modification processGO:00362111000.013
viral processGO:001603210.013
membrane invaginationGO:001032410.013
rna export from nucleusGO:000640510.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
signal transduction in absence of ligandGO:003803410.013
regulation of signal transductionGO:00099662250.013
regulation of response to biotic stimulusGO:000283120.013
antimicrobial humoral responseGO:001973020.013
protein dephosphorylationGO:000647030.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
cytoskeleton dependent cytokinesisGO:006164030.012
positive regulation of secretion by cellGO:190353210.012
regulation of protein ubiquitinationGO:003139630.012
phosphorus metabolic processGO:00067931090.012
chemosensory behaviorGO:000763510.012
regulation of reactive oxygen species metabolic processGO:200037720.012
hormone secretionGO:004687920.012
secondary metabolic processGO:001974830.012
cell substrate adhesionGO:003158940.012
neuron projection developmentGO:00311751800.012
cellular component assembly involved in morphogenesisGO:00109271070.012
single fertilizationGO:000733830.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
negative regulation of protein localization to nucleusGO:190018120.012
negative regulation of cellular catabolic processGO:003133030.012
regulation of cell differentiationGO:00455951420.012
hemopoiesisGO:00300971830.012
axon developmentGO:00615641660.012
rna modificationGO:000945120.012
response to external stimulusGO:00096052640.012
anterior posterior pattern specificationGO:00099521520.012
development of primary female sexual characteristicsGO:004654540.012
mitotic dna integrity checkpointGO:004477440.012
synaptic vesicle localizationGO:009747910.012
positive regulation of cellular processGO:00485222010.012
regulation of organ growthGO:004662030.012
developmental programmed cell deathGO:001062340.012
convergent extensionGO:00600261180.012
negative regulation of metabolic processGO:0009892860.012
negative regulation of rna splicingGO:003311910.012
primary neural tube formationGO:001402010.012
cell motilityGO:00488702440.012
regulation of rna biosynthetic processGO:20011412130.012
sequestering of calcium ionGO:005120830.012
double strand break repair via homologous recombinationGO:000072410.012
oocyte anterior posterior axis specificationGO:000731440.012
positive regulation of gtpase activityGO:004354710.012
gastrulationGO:00073692080.012
cellular response to molecule of bacterial originGO:007121930.012
regulation of production of molecular mediator of immune responseGO:000270010.012
lipid homeostasisGO:005508830.012
apoptotic processGO:00069151160.012
positive regulation of map kinase activityGO:004340630.012
negative regulation of intracellular protein transportGO:009031730.012
nuclear exportGO:005116810.012
muscle structure developmentGO:00610611960.012
positive regulation of jnk cascadeGO:004633030.012
response to nutrientGO:000758430.012
regulation of transporter activityGO:003240920.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
digestive system developmentGO:00551232890.012
regulation of sequestering of calcium ionGO:005128240.012
response to glucoseGO:000974930.012
golgi vesicle transportGO:004819330.011
startle responseGO:000196440.011
carbohydrate homeostasisGO:003350010.011
regulation of dendrite developmentGO:005077330.011
cellular response to decreased oxygen levelsGO:003629410.011
negative regulation of macromolecule metabolic processGO:0010605760.011
double strand break repairGO:000630230.011
activation of mapk activityGO:000018730.011
peptidyl serine modificationGO:001820920.011
regulation of dna replicationGO:000627530.011
female meiotic divisionGO:000714320.011
regulation of neurotransmitter transportGO:005158810.011
regulation of chromosome segregationGO:005198310.011
dorsal ventral pattern formationGO:00099531250.011
response to organic substanceGO:00100331530.011
gland developmentGO:00487321430.011
negative regulation of reproductive processGO:200024230.011
mitochondrial transportGO:000683920.011
regulation of calcium ion transportGO:005192420.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
cell matrix adhesionGO:000716040.011
lipid oxidationGO:003444010.011
deathGO:00162651210.011
rna 3 end processingGO:003112320.011
dna templated transcription elongationGO:000635430.011
cell cycle arrestGO:000705010.011
regulation of ion transmembrane transporter activityGO:003241220.011
establishment of rna localizationGO:005123630.011
cell deathGO:00082191210.011
phosphate containing compound metabolic processGO:00067961080.011
negative regulation of signalingGO:0023057960.011
macroautophagyGO:001623610.011
chordate embryonic developmentGO:00430092710.011
protein polyubiquitinationGO:000020940.011
specification of symmetryGO:00097992040.011
cellular response to radiationGO:007147840.011
digestive tract morphogenesisGO:00485462310.011
positive regulation of canonical wnt signaling pathwayGO:009026340.011
sequestering of metal ionGO:005123830.011
transmission of nerve impulseGO:0019226190.011
regulation of neurotransmitter secretionGO:004692810.011
cellular respirationGO:004533330.011
regulation of protein complex disassemblyGO:004324410.011
mitotic dna damage checkpointGO:004477340.011
negative regulation of protein import into nucleusGO:004230820.010
intracellular signal transductionGO:0035556850.010
negative regulation of defense responseGO:003134820.010
toll like receptor signaling pathwayGO:000222440.010
neuron neuron synaptic transmissionGO:000727010.010
positive regulation of cell adhesionGO:004578510.010
negative regulation of translationGO:001714810.010
camera type eye developmentGO:00430102220.010
cell substrate junction assemblyGO:000704420.010
negative regulation of gene expressionGO:0010629650.010
cellular response to lipopolysaccharideGO:007122230.010
neuron projection morphogenesisGO:00488121610.010
regulation of stem cell differentiationGO:200073640.010
peptidyl serine phosphorylationGO:001810510.010
negative regulation of cellular metabolic processGO:0031324770.010
establishment of protein localization to plasma membraneGO:009000210.010
neuromuscular synaptic transmissionGO:000727420.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
cilium morphogenesisGO:0060271850.010
negative regulation of signal transductionGO:0009968940.010
negative regulation of multi organism processGO:004390130.010
segmentationGO:0035282970.010
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.010
multicellular organismal metabolic processGO:004423620.010
monocarboxylic acid catabolic processGO:007232930.010
response to corticosteroidGO:003196010.010

tp53rk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.022
musculoskeletal system diseaseDOID:1700.021
disease of metabolismDOID:001466700.016
muscular diseaseDOID:008000000.015
muscle tissue diseaseDOID:6600.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
inherited metabolic disorderDOID:65500.013
myopathyDOID:42300.012