Danio rerio

37 known processes

atp2a1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

(Aliases: serca1,MGC92110,zgc:92110,wu:fb17h11,cb279,serca,wu:cegs655,wu:fb19b10)

atp2a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular component assemblyGO:00226071700.813
Worm
cellular component morphogenesisGO:00329893360.777
Worm
myofibril assemblyGO:0030239480.681
Worm
cell morphogenesis involved in neuron differentiationGO:00486671630.671
neuron differentiationGO:00301823530.657
ventricular cardiac myofibril assemblyGO:005500540.547
actin cytoskeleton organizationGO:0030036630.544
Worm
neuron developmentGO:00486662620.544
regulation of axon extensionGO:0030516240.524
positive regulation of biological processGO:00485182530.514
Fly
cell morphogenesisGO:00009022890.470
generation of neuronsGO:00486993850.469
single organism organelle organizationGO:19025891990.467
Worm
cellular component biogenesisGO:00440851780.463
Worm
actomyosin structure organizationGO:0031032530.463
Worm
muscle system processGO:0003012200.454
growth plate cartilage morphogenesisGO:000342210.450
muscle structure developmentGO:00610611960.441
Worm
axonogenesisGO:00074091520.398
response to external stimulusGO:00096052640.382
circulatory system processGO:0003013870.375
Zebrafish Fly
cell morphogenesis involved in differentiationGO:00009041950.366
organelle organizationGO:00069962270.356
Worm
heart morphogenesisGO:00030071560.317
Zebrafish
heart processGO:0003015710.316
Zebrafish Fly
heart contractionGO:0060047710.313
Zebrafish Fly
muscle cell differentiationGO:00426921390.309
Worm
cell projection morphogenesisGO:00488582440.299
heart developmentGO:00075073130.282
Zebrafish
muscle tissue developmentGO:00605371100.276
regulation of multicellular organismal processGO:00512392770.262
muscle cell developmentGO:00550011150.244
Worm
urogenital system developmentGO:0001655970.243
muscle contractionGO:0006936180.243
cell growthGO:0016049570.241
cell part morphogenesisGO:00329902460.230
neuron projection developmentGO:00311751800.222
striated muscle cell differentiationGO:00511461290.221
Worm
heterocycle metabolic processGO:00464832900.219
Worm Fly
regulation of signalingGO:00230512350.213
locomotionGO:00400113130.213
actin filament based processGO:0030029640.207
Worm
cardiocyte differentiationGO:0035051440.203
system processGO:00030081850.199
axon extensionGO:0048675450.196
regulation of biological qualityGO:00650082630.193
regulation of heart contractionGO:0008016320.189
Zebrafish
neuron projection extensionGO:1990138450.185
regulation of axonogenesisGO:0050770320.185
atp catabolic processGO:000620040.182
Worm Fly
axon developmentGO:00615641660.181
sensory perceptionGO:0007600390.181
negative regulation of biological processGO:00485193040.180
neuron projection morphogenesisGO:00488121610.179
sensory organ developmentGO:00074233930.176
response to chemicalGO:00422213200.172
Worm
purine nucleoside monophosphate catabolic processGO:000912840.169
Worm Fly
cellular modified amino acid metabolic processGO:000657530.167
striated muscle cell developmentGO:00550021080.165
Worm
chordate embryonic developmentGO:00430092710.161
larval developmentGO:000216420.155
Worm
taxisGO:00423301090.154
membrane repolarizationGO:008600920.153
regulation of developmental processGO:00507932470.153
establishment of localizationGO:00512342440.151
Worm Fly
cellular amino acid biosynthetic processGO:000865220.147
embryo development ending in birth or egg hatchingGO:00097922710.145
Worm
ion transportGO:00068111140.140
Worm Fly
developmental growth involved in morphogenesisGO:0060560860.137
behaviorGO:0007610740.136
Fly
cardiac muscle cell differentiationGO:0055007300.130
reactive nitrogen species metabolic processGO:200105700.129
neurological system processGO:0050877620.126
regulation of cell communicationGO:00106462320.123
embryonic organ developmentGO:00485683810.122
Zebrafish
positive regulation of cell deathGO:0010942290.117
regulation of blood circulationGO:1903522320.114
Zebrafish
regulation of rna metabolic processGO:00512522240.113
macromolecule biosynthetic processGO:00090592270.111
cell recognitionGO:0008037190.109
ventricular cardiac muscle cell developmentGO:005501550.105
cellular component movementGO:00069283350.104
cell motilityGO:00488702440.103
ventricular cardiac muscle tissue morphogenesisGO:005501020.099
protein importGO:001703830.092
sarcomere organizationGO:0045214260.091
reactive oxygen species biosynthetic processGO:190340910.091
nucleobase containing compound metabolic processGO:00061392740.090
Worm Fly
striated muscle tissue developmentGO:00147061100.089
positive regulation of blood circulationGO:190352420.089
pronephros developmentGO:0048793690.088
female sex differentiationGO:004666040.087
inner ear morphogenesisGO:0042472630.086
response to organic substanceGO:00100331530.083
Worm
eye developmentGO:00016542770.083
lipid storageGO:001991510.083
Fly
anatomical structure homeostasisGO:0060249360.082
cell migrationGO:00164772370.082
cellular amino acid metabolic processGO:000652070.082
skin developmentGO:0043588540.081
blood circulationGO:0008015870.081
Zebrafish Fly
regulation of cellular component sizeGO:0032535300.077
neuron projection guidanceGO:0097485860.076
adult behaviorGO:003053420.072
Fly
chemotaxisGO:00069351040.072
nucleoside monophosphate catabolic processGO:000912540.071
Worm Fly
cytokinesisGO:000091030.070
carboxylic acid metabolic processGO:0019752220.069
Fly
single organism localizationGO:19025782250.069
Worm Fly
nitrogen compound metabolic processGO:00068073190.068
Worm Fly
regulation of signal transductionGO:00099662250.068
cellular localizationGO:0051641970.068
stem cell differentiationGO:00488631170.066
Fly
skeletal muscle thin filament assemblyGO:003024040.066
regulation of cell differentiationGO:00455951420.065
cell projection organizationGO:00300302840.064
regulation of cell sizeGO:0008361290.064
programmed cell deathGO:00125011190.063
Worm
developmental cell growthGO:0048588520.063
oxoacid metabolic processGO:0043436310.062
Fly
regulation of cellular macromolecule biosynthetic processGO:20001122220.062
growthGO:00400071740.062
macromolecular complex assemblyGO:0065003350.062
Worm
regulation of behaviorGO:0050795240.062
regulation of cellular component organizationGO:0051128860.061
head developmentGO:00603223030.060
regulation of neurogenesisGO:0050767870.060
regulation of muscle contractionGO:000693730.060
metal ion transportGO:0030001580.059
Worm Fly
regulation of myotube differentiationGO:001083020.059
regulation of cell deathGO:00109411030.058
transportGO:00068102200.057
Worm Fly
renal system developmentGO:0072001940.057
central nervous system developmentGO:00074173870.056
heart loopingGO:0001947940.056
Zebrafish
organic acid metabolic processGO:0006082310.056
Fly
axon guidanceGO:0007411860.056
camera type eye developmentGO:00430102220.056
cation transportGO:0006812810.055
Worm Fly
morphogenesis of an epitheliumGO:00020093330.054
Zebrafish
cell fate commitmentGO:0045165990.054
cell deathGO:00082191210.054
Worm
cellular biosynthetic processGO:00442492860.053
protein localization to nucleusGO:003450430.053
signal transductionGO:00071654550.052
Worm
digestive tract developmentGO:00485652650.052
neuromuscular synaptic transmissionGO:000727420.052
Fly
regulation of cell morphogenesis involved in differentiationGO:0010769380.051
growth plate cartilage developmentGO:000341720.051
vasculature developmentGO:00019442780.051
regulation of locomotionGO:0040012550.050
actin filament based movementGO:003004810.050
positive regulation of heart contractionGO:004582320.050
positive regulation of cellular processGO:00485222010.050
Fly
lymphoid lineage cell migrationGO:009753440.050
organonitrogen compound metabolic processGO:1901564740.050
Worm Fly
cytoskeleton organizationGO:0007010960.050
Worm
translational initiationGO:000641330.049
organic cyclic compound metabolic processGO:19013603010.049
Worm Fly
kidney developmentGO:0001822920.049
regulation of cell growthGO:0001558290.049
regulation of anatomical structure sizeGO:0090066330.048
regulation of establishment of protein localizationGO:007020140.048
ear developmentGO:00435831270.048
regulation of macromolecule biosynthetic processGO:00105562250.048
blood vessel developmentGO:00015682460.048
ion transmembrane transportGO:0034220910.048
Worm Fly
regulation of cellular metabolic processGO:00313233200.048
Fly
motor neuron axon guidanceGO:0008045230.047
ventricular cardiac muscle cell differentiationGO:005501260.047
regulation of primary metabolic processGO:00800903110.047
Fly
homeostatic processGO:00425921420.047
gene expressionGO:00104672520.046
post embryonic morphogenesisGO:000988640.045
blood vessel morphogenesisGO:00485142160.044
cellular response to external stimulusGO:007149620.044
nucleocytoplasmic transportGO:000691340.043
small molecule metabolic processGO:0044281770.043
Worm Fly
single organism transportGO:00447652060.043
Worm Fly
regulation of reproductive processGO:200024140.043
apoptotic processGO:00069151160.043
Worm
transmembrane transportGO:00550851200.043
Worm Fly
regulation of programmed cell deathGO:00430671010.042
ribonucleoside monophosphate catabolic processGO:000915840.042
Worm Fly
negative regulation of kinase activityGO:003367340.042
regulation of metabolic processGO:00192223590.042
Fly
cytoplasm organizationGO:000702840.041
localization of cellGO:00516742440.040
locomotory behaviorGO:0007626340.040
Fly
negative regulation of cellular processGO:00485232830.040
inner ear developmentGO:00488391260.040
response to abiotic stimulusGO:00096281220.040
regulation of transmembrane transportGO:0034762180.040
Fly
regulation of epithelial cell proliferationGO:005067830.039
single organism biosynthetic processGO:0044711710.039
Fly
nerve developmentGO:0021675450.039
lymphoid lineage cell migration into thymusGO:009753540.039
epithelial cell developmentGO:0002064420.038
cardiac cell developmentGO:0055006210.038
determination of bilateral symmetryGO:00098552040.038
Zebrafish
reproductive processGO:0022414400.038
Worm
organelle assemblyGO:00709251100.037
Worm
response to drugGO:004249330.037
cartilage development involved in endochondral bone morphogenesisGO:006035180.037
regulation of extent of cell growthGO:0061387290.037
cellular macromolecule biosynthetic processGO:00346452240.037
developmental growthGO:00485891660.037
cellular ketone metabolic processGO:0042180110.036
negative regulation of axon guidanceGO:190266810.036
regulation of mrna processingGO:005068430.036
nuclear importGO:005117030.035
phosphorus metabolic processGO:00067931090.035
Worm Fly
cellular nitrogen compound biosynthetic processGO:00442712180.035
establishment of protein localization to organelleGO:007259440.035
cellular component assembly involved in morphogenesisGO:00109271070.035
Worm
phosphate containing compound metabolic processGO:00067961080.034
Worm Fly
negative regulation of protein phosphorylationGO:000193340.034
atrial cardiac myofibril assemblyGO:005500420.034
basement membrane assemblyGO:007083130.034
cell substrate adhesionGO:003158940.034
regulation of intracellular signal transductionGO:1902531570.034
stem cell proliferationGO:007208940.034
regulation of cytoplasmic transportGO:190364940.034
muscle organ developmentGO:00075171010.034
biological adhesionGO:0022610400.034
regulation of protein import into nucleusGO:004230620.034
nuclear transportGO:005116940.033
positive regulation of cellular catabolic processGO:003133130.033
Fly
chondrocyte intercalation involved in growth plate cartilage morphogenesisGO:000342810.032
positive regulation of neuron apoptotic processGO:004352510.032
membrane organizationGO:0061024210.032
regulation of apoptotic processGO:0042981980.032
maintenance of locationGO:005123540.032
Fly
macromolecular complex subunit organizationGO:0043933740.032
Worm
synaptic transmission cholinergicGO:000727140.031
protein complex subunit organizationGO:0071822460.031
Worm
reactive oxygen species metabolic processGO:007259360.031
protein metabolic processGO:00195381830.030
regulation of anatomical structure morphogenesisGO:00226031300.030
cellular response to organic cyclic compoundGO:0071407380.030
brain developmentGO:00074202930.030
female gonad developmentGO:000858540.030
regulation of endothelial cell proliferationGO:000193610.030
cellular macromolecule localizationGO:0070727210.029
cellular amine metabolic processGO:004410620.029
pigmentationGO:0043473850.029
protein heterooligomerizationGO:005129110.029
positive regulation of muscle cell differentiationGO:005114910.028
macromolecule localizationGO:0033036540.028
Fly
single organism cellular localizationGO:1902580460.028
regulation of peptidyl tyrosine phosphorylationGO:005073010.028
response to endogenous stimulusGO:0009719830.028
negative regulation of protein kinase activityGO:000646940.028
single organism behaviorGO:0044708240.027
Fly
sensory organ morphogenesisGO:00905962000.027
skeletal system developmentGO:00015011810.027
biosynthetic processGO:00090582940.027
Fly
nucleic acid metabolic processGO:00903042440.027
protein targeting to nucleusGO:004474430.026
axonal fasciculationGO:0007413110.026
deathGO:00162651210.026
Worm
positive regulation of cellular amino acid metabolic processGO:004576400.026
regulation of cellular biosynthetic processGO:00313262450.025
meiotic nuclear divisionGO:000712640.025
hair cell differentiationGO:0035315320.025
single organism nuclear importGO:190259330.025
mesenchyme developmentGO:00604851270.025
protein polymerizationGO:005125840.025
protein import into nucleusGO:000660630.024
epithelial cell differentiationGO:00308551160.024
negative regulation of cell growthGO:003030870.024
response to corticosteroidGO:003196010.024
post embryonic organ developmentGO:004856940.024
lamellipodium assemblyGO:003003210.024
nitric oxide metabolic processGO:004620920.023
cellular response to organic substanceGO:00713101050.023
Worm
regulation of multicellular organismal developmentGO:20000262230.023
positive regulation of secretion by cellGO:190353210.023
regulation of localizationGO:00328791040.023
Fly
regionalizationGO:00030022740.023
muscle cell fate commitmentGO:004269390.022
mitotic cytokinesisGO:000028130.022
ear morphogenesisGO:0042471640.022
regulation of macromolecule metabolic processGO:00602553170.022
anterior posterior pattern specificationGO:00099521520.022
regulation of synaptic plasticityGO:004816710.022
muscle fiber developmentGO:0048747520.022
regulation of cell projection assemblyGO:006049140.022
establishment of localization in cellGO:0051649770.022
organonitrogen compound biosynthetic processGO:1901566470.021
cardiac muscle tissue morphogenesisGO:005500870.021
positive regulation of apoptotic processGO:0043065290.021
cell cell signalingGO:0007267520.021
Fly
inner ear receptor cell differentiationGO:0060113290.021
endochondral bone growthGO:000341620.021
er nucleus signaling pathwayGO:000698420.021
Worm
cellular macromolecular complex assemblyGO:0034622240.021
Worm
directional locomotionGO:003305810.020
positive regulation of transportGO:005105020.020
Fly
response to woundingGO:00096111160.020
response to amineGO:001407510.020
proteolysis involved in cellular protein catabolic processGO:005160330.020
cellular nitrogen compound metabolic processGO:00346412900.020
Worm Fly
positive regulation of secretionGO:005104710.020
purine ribonucleoside monophosphate catabolic processGO:000916940.020
Worm Fly
positive regulation of cell communicationGO:0010647560.020
response to stressGO:00069502630.020
Worm
multicellular organism growthGO:003526440.020
tube morphogenesisGO:00352393490.020
Zebrafish
retina development in camera type eyeGO:00600411460.020
mitotic cell cycle processGO:1903047480.019
cytoskeleton dependent cytokinesisGO:006164030.019
photoreceptor cell developmentGO:0042461400.019
mitochondrion organizationGO:000700540.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of calcium ion transportGO:005192420.019
Fly
cation transmembrane transportGO:0098655650.019
Worm Fly
protein localization to membraneGO:007265790.019
regulation of membrane potentialGO:0042391230.019
Fly
regulation of tube sizeGO:003515020.019
regulation of protein kinase b signalingGO:005189680.018
cellular response to stressGO:0033554620.018
Worm
cell surface receptor signaling pathwayGO:00071663250.018
negative regulation of epithelial cell proliferationGO:005068010.018
camera type eye morphogenesisGO:00485931080.018
development of primary female sexual characteristicsGO:004654540.018
specification of axis polarityGO:006500140.018
cardiac muscle tissue developmentGO:0048738480.018
single organism metabolic processGO:00447102170.018
Worm Fly
protein localization to plasma membraneGO:007265910.018
multi organism processGO:00517041340.018
Worm
positive regulation of gene expressionGO:0010628710.018
negative regulation of biosynthetic processGO:0009890550.018
single organism membrane organizationGO:0044802200.018
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
convergent extension involved in organogenesisGO:0060029100.017
agingGO:000756820.017
Worm
positive regulation of neuron deathGO:190121610.017
regulation of transportGO:0051049450.017
Fly
response to oxygen containing compoundGO:1901700550.017
ion homeostasisGO:0050801410.017
regulation of intracellular protein transportGO:003315730.017
muscle organ morphogenesisGO:004864480.017
neuron neuron synaptic transmissionGO:000727010.017
rna metabolic processGO:00160702190.017
immune system processGO:00023762410.017
notochord cell differentiationGO:0060034180.017
response to amino acidGO:004320020.017
cellular aromatic compound metabolic processGO:00067252950.017
Worm Fly
extrinsic apoptotic signaling pathwayGO:009719130.017
regulation of system processGO:0044057400.016
positive regulation of cellular amine metabolic processGO:003324000.016
regulation of cellular ketone metabolic processGO:001056570.016
positive regulation of cellular component biogenesisGO:004408930.016
digestive system developmentGO:00551232890.016
positive regulation of multicellular organismal processGO:0051240520.016
nitric oxide biosynthetic processGO:000680920.016
somatic muscle developmentGO:000752540.016
regulation of nitric oxide mediated signal transductionGO:001074910.016
central nervous system neuron differentiationGO:0021953740.016
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.016
regulation of response to cytokine stimulusGO:006075930.016
rna biosynthetic processGO:00327741810.015
regulation of protein localization to nucleusGO:190018020.015
cell cycleGO:0007049930.015
negative regulation of metabolic processGO:0009892860.015
mesoderm developmentGO:0007498880.015
negative regulation of developmental processGO:0051093650.015
positive regulation of programmed cell deathGO:0043068290.015
regulation of protein targetingGO:190353320.015
cell matrix adhesionGO:000716040.015
ribosome assemblyGO:004225510.015
eye morphogenesisGO:00485921440.015
organic cyclic compound biosynthetic processGO:19013622230.015
cellular calcium ion homeostasisGO:0006874130.015
connective tissue developmentGO:0061448990.015
regulation of response to stimulusGO:00485832690.014
somitogenesisGO:0001756870.014
positive regulation of nucleic acid templated transcriptionGO:1903508570.014
regulation of nucleocytoplasmic transportGO:004682220.014
angiogenesisGO:00015251580.014
notochord developmentGO:0030903540.014
cellular response to extracellular stimulusGO:003166820.014
proteasomal protein catabolic processGO:001049820.014
cellular response to chemical stimulusGO:00708871570.014
Worm
negative regulation of apoptotic processGO:0043066550.014
protein complex assemblyGO:0006461300.014
Worm
dendrite guidanceGO:007098300.014
negative regulation of protein complex assemblyGO:003133310.014
response to radiationGO:0009314510.014
regulation of multicellular organism growthGO:004001440.014
positive regulation of transcription dna templatedGO:0045893570.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
neuron cellular homeostasisGO:007005030.014
regulation of cell morphogenesisGO:0022604420.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
organic substance biosynthetic processGO:19015762890.013
Fly
endocardial cushion morphogenesisGO:000320330.013
regulation of striated muscle contractionGO:000694220.013
phosphorylationGO:0016310690.013
response to nutrientGO:000758430.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
negative regulation of signal transductionGO:0009968940.013
small molecule catabolic processGO:004428230.013
Fly
positive regulation of developmental processGO:0051094500.013
pronephros morphogenesisGO:0072114140.013
regulation of cell projection organizationGO:0031344440.013
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
synaptic growth at neuromuscular junctionGO:005112420.012
regulation of cytokine productionGO:000181730.012
cell adhesionGO:0007155400.012
intracellular signal transductionGO:0035556850.012
amine metabolic processGO:000930820.012
cardiac chamber morphogenesisGO:0003206120.012
negative regulation of cell migrationGO:0030336170.012
purine nucleotide metabolic processGO:0006163270.012
Worm Fly
cardiac myofibril assemblyGO:005500390.012
regulation of protein complex assemblyGO:004325430.012
positive regulation of signalingGO:0023056560.012
protein localizationGO:0008104400.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
Fly
endocardial cushion formationGO:000327220.012
regulation of protein polymerizationGO:003227120.012
cellular protein localizationGO:0034613200.012
nucleobase containing compound biosynthetic processGO:00346542050.012
mitotic cell cycleGO:0000278640.011
negative regulation of response to stimulusGO:00485851040.011
transcription from rna polymerase ii promoterGO:0006366800.011
response to mechanical stimulusGO:0009612240.011
neural crest cell developmentGO:0014032620.011
ubiquitin dependent protein catabolic processGO:000651130.011
inorganic ion transmembrane transportGO:0098660570.011
Worm Fly
alternative mrna splicing via spliceosomeGO:000038010.011
ventricular cardiac muscle tissue developmentGO:000322930.011
dorsal ventral pattern formationGO:00099531250.011
outflow tract morphogenesisGO:000315110.011
mesenchymal cell differentiationGO:0048762870.011
actin filament organizationGO:0007015150.011
regulation of protein complex disassemblyGO:004324410.011
protein complex disassemblyGO:004324110.011
cellular response to radiationGO:007147840.011
regulation of biosynthetic processGO:00098892500.011
regulation of cardiac muscle contractionGO:005511720.011
hemopoiesisGO:00300971830.011
tissue regenerationGO:0042246740.011
extracellular matrix organizationGO:0030198270.011
mesenchymal cell developmentGO:0014031780.011
action potentialGO:0001508190.011
endomembrane system organizationGO:0010256130.010
aromatic compound biosynthetic processGO:00194382170.010
striated muscle contractionGO:0006941120.010
stem cell divisionGO:001714510.010
enzyme linked receptor protein signaling pathwayGO:00071671060.010
odontogenesis of dentin containing toothGO:004247510.010
divalent metal ion transportGO:0070838200.010
Worm Fly
regulation of response to external stimulusGO:0032101310.010
circadian sleep wake cycleGO:004274520.010
neural crest cell migrationGO:0001755420.010
organic anion transportGO:0015711150.010
monovalent inorganic cation transportGO:0015672420.010
cellular component disassemblyGO:002241110.010

atp2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.176
musculoskeletal system diseaseDOID:1700.123
nervous system diseaseDOID:86300.023
muscle tissue diseaseDOID:6600.020
muscular diseaseDOID:008000000.020
cardiovascular system diseaseDOID:128700.020
myopathyDOID:42300.011
heart diseaseDOID:11400.011
cardiomyopathyDOID:005070000.011