Danio rerio

38 known processes

rac1

ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

(Aliases: zgc:55823,zgc:86934,MGC55823,zgc:55917,wu:fd16e02)

rac1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular metabolic processGO:00313233200.316
neuron developmentGO:00486662620.241
digestive system developmentGO:00551232890.226
neuron projection developmentGO:00311751800.209
positive regulation of cellular processGO:00485222010.209
regulation of mrna processingGO:005068430.208
regulation of biological qualityGO:00650082630.207
regulation of cell communicationGO:00106462320.206
response to stressGO:00069502630.196
regulation of multicellular organismal developmentGO:20000262230.194
regulation of metabolic processGO:00192223590.182
signal transductionGO:00071654550.177
convergent extensionGO:00600261180.175
positive regulation of biological processGO:00485182530.173
positive regulation of transportGO:005105020.173
morphogenesis of an epitheliumGO:00020093330.168
biosynthetic processGO:00090582940.167
cellular component assemblyGO:00226071700.164
organelle organizationGO:00069962270.154
cellular component movementGO:00069283350.151
positive regulation of catalytic activityGO:0043085250.149
regulation of cellular biosynthetic processGO:00313262450.141
negative regulation of biological processGO:00485193040.137
response to chemicalGO:00422213200.137
developmental growthGO:00485891660.127
regulation of developmental processGO:00507932470.126
establishment of localizationGO:00512342440.123
regulation of macromolecule metabolic processGO:00602553170.122
response to external biotic stimulusGO:0043207970.121
regulation of protein import into nucleusGO:004230620.117
regulation of cell shapeGO:000836010.116
regulation of gene expressionGO:00104682650.115
positive regulation of metabolic processGO:00098931080.113
regulation of biosynthetic processGO:00098892500.113
neuroblast proliferationGO:000740520.113
nuclear importGO:005117030.113
cytokinesisGO:000091030.112
establishment of protein localization to plasma membraneGO:009000210.112
dna catabolic processGO:000630810.111
organic substance biosynthetic processGO:19015762890.111
regulation of cell differentiationGO:00455951420.109
growthGO:00400071740.109
response to external stimulusGO:00096052640.109
regulation of nitrogen compound metabolic processGO:00511712510.107
positive regulation of secretion by cellGO:190353210.106
regulation of rna biosynthetic processGO:20011412130.105
single organism organelle organizationGO:19025891990.102
digestive tract developmentGO:00485652650.100
nucleobase containing compound biosynthetic processGO:00346542050.099
determination of bilateral symmetryGO:00098552040.096
regulation of signalingGO:00230512350.096
cellular component morphogenesisGO:00329893360.096
negative regulation of cellular processGO:00485232830.094
transportGO:00068102200.092
organic cyclic compound biosynthetic processGO:19013622230.090
cytoskeleton organizationGO:0007010960.089
gtp catabolic processGO:000618420.088
tube morphogenesisGO:00352393490.088
cell surface receptor signaling pathwayGO:00071663250.088
gene expressionGO:00104672520.087
stem cell divisionGO:001714510.086
regulation of nucleic acid templated transcriptionGO:19035062130.084
generation of neuronsGO:00486993850.084
maintenance of locationGO:005123540.084
cell morphogenesisGO:00009022890.083
cellular macromolecule biosynthetic processGO:00346452240.082
locomotionGO:00400113130.082
cellular nitrogen compound biosynthetic processGO:00442712180.082
regulation of primary metabolic processGO:00800903110.082
cortical actin cytoskeleton organizationGO:003086610.082
immune system processGO:00023762410.081
synaptic growth at neuromuscular junctionGO:005112420.081
cellular biosynthetic processGO:00442492860.079
hematopoietic or lymphoid organ developmentGO:00485341910.077
positive regulation of macromolecule metabolic processGO:0010604930.076
phosphorus metabolic processGO:00067931090.075
microtubule cytoskeleton organization involved in mitosisGO:190285010.075
system processGO:00030081850.075
organonitrogen compound metabolic processGO:1901564740.075
regulation of cell activationGO:005086510.074
gastrulationGO:00073692080.074
chemosensory behaviorGO:000763510.073
phosphate containing compound metabolic processGO:00067961080.072
guanosine containing compound metabolic processGO:190106840.072
regulation of protein localization to nucleusGO:190018020.072
regulation of rna metabolic processGO:00512522240.072
digestive tract morphogenesisGO:00485462310.070
negative regulation of epithelial cell proliferationGO:005068010.070
rna metabolic processGO:00160702190.069
single organism metabolic processGO:00447102170.069
cell part morphogenesisGO:00329902460.068
cellular aromatic compound metabolic processGO:00067252950.068
regulation of nucleobase containing compound metabolic processGO:00192192500.066
cell projection organizationGO:00300302840.066
embryonic heart tube developmentGO:00350501330.066
regulation of catalytic activityGO:0050790550.065
establishment of localization in cellGO:0051649770.064
immune responseGO:0006955280.062
protein targeting to nucleusGO:004474430.061
stem cell proliferationGO:007208940.061
small molecule metabolic processGO:0044281770.061
protein localization to nucleusGO:003450430.061
macromolecule biosynthetic processGO:00090592270.059
neuron projection morphogenesisGO:00488121610.059
cortical cytoskeleton organizationGO:003086510.059
positive regulation of chromatin modificationGO:190331010.059
neurotransmitter transportGO:000683620.058
positive regulation of cell cycleGO:004578730.058
localization of cellGO:00516742440.058
cellular nitrogen compound metabolic processGO:00346412900.058
cellular component biogenesisGO:00440851780.057
protein metabolic processGO:00195381830.057
regulation of macromolecule biosynthetic processGO:00105562250.057
ribonucleotide metabolic processGO:0009259270.056
reflexGO:006000420.054
heterocycle biosynthetic processGO:00181302150.054
transcription dna templatedGO:00063511810.053
adherens junction organizationGO:003433240.053
cell agingGO:000756920.053
response to nutrientGO:000758430.052
positive regulation of exocytosisGO:004592110.052
regulation of protein targetingGO:190353320.052
blood vessel morphogenesisGO:00485142160.052
ubiquitin dependent protein catabolic processGO:000651130.051
regulation of signal transductionGO:00099662250.051
organic substance transportGO:0071702580.051
purine nucleoside monophosphate catabolic processGO:000912840.051
single organism localizationGO:19025782250.051
positive regulation of cellular component biogenesisGO:004408930.050
cellular protein metabolic processGO:00442671290.050
actin polymerization or depolymerizationGO:000815420.049
regulation of molecular functionGO:0065009700.048
cell fate commitmentGO:0045165990.048
sequestering of metal ionGO:005123830.048
regulation of establishment of protein localizationGO:007020140.048
regulation of response to stimulusGO:00485832690.048
agingGO:000756820.048
nitrogen compound metabolic processGO:00068073190.047
regulation of synaptic growth at neuromuscular junctionGO:000858210.047
aromatic compound biosynthetic processGO:00194382170.047
actin filament based processGO:0030029640.047
organic cyclic compound metabolic processGO:19013603010.047
cellular ketone metabolic processGO:0042180110.046
regulation of cell deathGO:00109411030.046
cell cell junction assemblyGO:000704350.046
tissue regenerationGO:0042246740.045
regulation of cytoplasmic transportGO:190364940.045
response to glucoseGO:000974930.045
protein importGO:001703830.045
mitotic cell cycleGO:0000278640.044
positive regulation of secretionGO:005104710.044
nucleoside monophosphate catabolic processGO:000912540.044
neuron differentiationGO:00301823530.044
amine metabolic processGO:000930820.044
response to other organismGO:0051707970.043
positive regulation of muscle cell differentiationGO:005114910.043
regulation of tube sizeGO:003515020.043
macromolecular complex subunit organizationGO:0043933740.043
neurotransmitter secretionGO:000726920.043
heterocycle metabolic processGO:00464832900.042
regenerationGO:0031099910.042
cell cycleGO:0007049930.042
neural precursor cell proliferationGO:0061351200.042
nuclear transportGO:005116940.041
positive regulation of molecular functionGO:0044093330.041
negative regulation of nitrogen compound metabolic processGO:0051172590.041
heart morphogenesisGO:00030071560.040
cortical granule exocytosisGO:006047110.040
regulation of synapse assemblyGO:005196330.040
cell proliferationGO:0008283800.040
macromolecule localizationGO:0033036540.040
stem cell maintenanceGO:001982740.039
guanosine containing compound catabolic processGO:190106920.039
regulation of protein transportGO:005122330.038
protein localization to plasma membraneGO:007265910.038
protein secretionGO:000930610.038
somatic stem cell maintenanceGO:003501910.038
mitotic cell cycle processGO:1903047480.038
nucleocytoplasmic transportGO:000691340.038
regulation of gtp catabolic processGO:003312420.038
cellular macromolecule metabolic processGO:00442603910.037
regulation of epithelial cell proliferationGO:005067830.037
regulation of locomotionGO:0040012550.037
positive regulation of cellular metabolic processGO:0031325940.037
negative regulation of cellular catabolic processGO:003133030.037
detection of stimulusGO:0051606290.037
positive regulation of dna metabolic processGO:005105410.037
determination of left right symmetryGO:00073681790.036
regulation of apoptotic processGO:0042981980.036
cellular amine metabolic processGO:004410620.036
response to biotic stimulusGO:0009607970.036
larval developmentGO:000216420.036
double strand break repair via homologous recombinationGO:000072410.036
rna localizationGO:000640340.036
regulation of purine nucleotide catabolic processGO:003312120.036
negative regulation of biosynthetic processGO:0009890550.036
protein import into nucleusGO:000660630.035
response to hexoseGO:000974630.035
response to organic substanceGO:00100331530.035
hemopoiesisGO:00300971830.035
response to woundingGO:00096111160.034
regulation of neurogenesisGO:0050767870.034
protein modification processGO:00362111000.034
regulation of protein complex assemblyGO:004325430.034
regulation of skeletal muscle fiber developmentGO:004874220.034
multicellular organismal macromolecule metabolic processGO:004425920.034
actin cytoskeleton organizationGO:0030036630.034
proteolysis involved in cellular protein catabolic processGO:005160330.034
cellular localizationGO:0051641970.034
cell projection morphogenesisGO:00488582440.033
angiogenesisGO:00015251580.033
neurological system processGO:0050877620.033
regulation of localizationGO:00328791040.033
establishment of protein localization to organelleGO:007259440.033
rna biosynthetic processGO:00327741810.033
nucleobase containing compound metabolic processGO:00061392740.033
mitotic nuclear divisionGO:0007067180.033
head developmentGO:00603223030.032
cellular response to dna damage stimulusGO:0006974240.032
cellular protein catabolic processGO:004425740.032
regulation of multicellular organismal processGO:00512392770.032
regulation of nucleotide catabolic processGO:003081120.032
protein polymerizationGO:005125840.032
positive regulation of cellular amine metabolic processGO:003324000.032
macromolecule modificationGO:00434121110.032
meiotic cell cycle processGO:190304630.032
ameboidal type cell migrationGO:00016671430.031
cation homeostasisGO:0055080330.031
regulation of intracellular protein transportGO:003315730.031
cellular response to drugGO:003569010.031
regulation of reproductive processGO:200024140.031
response to carbohydrateGO:000974330.031
purine nucleotide biosynthetic processGO:0006164200.031
positive regulation of cellular amino acid metabolic processGO:004576400.031
gtp metabolic processGO:004603940.031
negative regulation of nucleobase containing compound metabolic processGO:0045934590.030
atp catabolic processGO:000620040.030
regulation of cellular component movementGO:0051270550.030
regulation of cellular amine metabolic processGO:003323800.030
determination of heart left right asymmetryGO:00613711170.029
cell migration involved in gastrulationGO:0042074790.029
regulation of cellular amino acid metabolic processGO:000652100.029
alternative mrna splicing via spliceosomeGO:000038010.029
negative regulation of catabolic processGO:000989530.029
regulation of synapse organizationGO:005080730.029
regulation of neurotransmitter secretionGO:004692810.028
photoreceptor cell outer segment organizationGO:003584590.028
response to drugGO:004249330.028
regulation of nucleocytoplasmic transportGO:004682220.028
programmed cell deathGO:00125011190.028
regulation of stem cell differentiationGO:200073640.028
female gonad developmentGO:000858540.027
specification of symmetryGO:00097992040.027
positive regulation of cytosolic calcium ion concentrationGO:000720440.027
cellular response to chemical stimulusGO:00708871570.027
phagocytosisGO:000690930.027
multicellular organism growthGO:003526440.027
reciprocal meiotic recombinationGO:000713110.027
deathGO:00162651210.027
cellular response to decreased oxygen levelsGO:003629410.027
multicellular organismal metabolic processGO:004423620.026
cell migrationGO:00164772370.026
regulation of oligodendrocyte differentiationGO:004871310.026
sensory perception of chemical stimulusGO:000760630.026
protein complex assemblyGO:0006461300.026
regulation of cellular macromolecule biosynthetic processGO:20001122220.026
cellular macromolecule localizationGO:0070727210.026
regulation of transcription dna templatedGO:00063552130.026
purine containing compound metabolic processGO:0072521290.026
response to radiationGO:0009314510.026
ribonucleoside monophosphate catabolic processGO:000915840.025
immune system developmentGO:00025201910.025
cytokinetic processGO:003250620.025
protein localizationGO:0008104400.025
regulation of blood pressureGO:000821710.025
regulation of organ growthGO:004662030.025
cellular catabolic processGO:0044248270.025
regulation of blood vessel sizeGO:005088020.025
circulatory system processGO:0003013870.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.024
single organism transportGO:00447652060.024
positive regulation of neuron apoptotic processGO:004352510.024
positive regulation of catabolic processGO:000989640.024
regulation of protein ubiquitinationGO:003139630.024
meiosis iGO:000712710.024
single organism cellular localizationGO:1902580460.024
positive regulation of protein complex assemblyGO:003133420.024
protein complex biogenesisGO:0070271300.024
oocyte anterior posterior axis specificationGO:000731440.024
heart developmentGO:00075073130.024
regulation of cellular ketone metabolic processGO:001056570.024
cellular response to stressGO:0033554620.023
collagen metabolic processGO:003296320.023
positive regulation of nitrogen compound metabolic processGO:0051173690.023
positive regulation of cell activationGO:005086710.023
g1 s transition of mitotic cell cycleGO:000008210.023
positive regulation of striated muscle cell differentiationGO:005115510.023
erythrocyte maturationGO:004324980.023
cell deathGO:00082191210.023
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.023
epithelial structure maintenanceGO:001066980.023
regulation of transportGO:0051049450.023
centrosome duplicationGO:005129810.023
single organism nuclear importGO:190259330.022
cytoskeleton dependent cytokinesisGO:006164030.022
cellular protein modification processGO:00064641000.022
regulation of phosphorus metabolic processGO:0051174430.022
anterior posterior pattern specificationGO:00099521520.022
embryonic organ developmentGO:00485683810.022
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.022
regulation of cellular component organizationGO:0051128860.022
homeostatic processGO:00425921420.022
actin filament polymerizationGO:003004120.021
odontogenesis of dentin containing toothGO:004247510.021
adult behaviorGO:003053420.021
negative regulation of sequestering of calcium ionGO:005128340.021
aromatic compound catabolic processGO:0019439150.021
spindle assemblyGO:005122520.021
reciprocal dna recombinationGO:003582510.021
dorsal ventral pattern formationGO:00099531250.021
central nervous system developmentGO:00074173870.021
regulation of skeletal muscle tissue developmentGO:004864140.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
modification dependent macromolecule catabolic processGO:004363230.021
negative regulation of multicellular organismal processGO:0051241690.021
regulation of protein bindingGO:004339330.021
carbohydrate homeostasisGO:003350010.021
response to abiotic stimulusGO:00096281220.021
organic substance catabolic processGO:1901575280.021
heart processGO:0003015710.021
embryonic heart tube morphogenesisGO:00031431080.021
regulation of vitamin metabolic processGO:003065660.020
positive regulation of histone modificationGO:003105810.020
lipid storageGO:001991510.020
epithelial tube morphogenesisGO:00605621480.020
cell substrate adhesionGO:003158940.020
g protein coupled receptor signaling pathwayGO:0007186740.020
protein complex subunit organizationGO:0071822460.020
regulation of myotube differentiationGO:001083020.020
response to glucocorticoidGO:005138410.019
negative regulation of protein transportGO:005122430.019
cell cycle g1 s phase transitionGO:004484310.019
purine ribonucleoside monophosphate catabolic processGO:000916940.019
development of primary female sexual characteristicsGO:004654540.019
regulation of nucleoside metabolic processGO:000911820.019
convergent extension involved in gastrulationGO:0060027710.019
positive regulation of oligodendrocyte differentiationGO:004871410.019
negative regulation of dna replicationGO:000815620.019
regulation of protein polymerizationGO:003227120.019
regulation of anatomical structure morphogenesisGO:00226031300.019
nucleobase containing small molecule metabolic processGO:0055086320.019
protein polyubiquitinationGO:000020940.019
organic acid metabolic processGO:0006082310.019
positive regulation of purine nucleotide catabolic processGO:003312310.019
protein localization to microtubule cytoskeletonGO:007269810.019
cellular response to organic substanceGO:00713101050.019
regulation of i kappab kinase nf kappab signalingGO:004312240.019
cell morphogenesis involved in neuron differentiationGO:00486671630.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
cellular response to retinoic acidGO:007130010.019
positive regulation of cellular catabolic processGO:003133130.018
recombinational repairGO:000072510.018
organophosphate metabolic processGO:0019637370.018
action potentialGO:0001508190.018
cellular macromolecular complex assemblyGO:0034622240.018
negative regulation of autophagyGO:001050710.018
somite developmentGO:0061053960.018
response to monosaccharideGO:003428430.018
mitochondrion organizationGO:000700540.018
purine nucleotide metabolic processGO:0006163270.018
taxisGO:00423301090.018
immunoglobulin productionGO:000237710.018
heart loopingGO:0001947940.017
defense response to other organismGO:0098542330.017
regulation of hormone secretionGO:004688320.017
regulation of alternative mrna splicing via spliceosomeGO:000038110.017
regulation of dna replicationGO:000627530.017
single organism intracellular transportGO:1902582250.017
exocytosisGO:000688710.017
vesicle mediated transportGO:0016192220.017
nucleotide metabolic processGO:0009117280.017
cell fate specificationGO:0001708680.017
cellular response to external stimulusGO:007149620.017
production of molecular mediator of immune responseGO:000244020.017
b cell differentiationGO:003018310.017
regulation of bindingGO:005109830.017
proximal distal pattern formationGO:000995410.017
intracellular transportGO:0046907320.017
negative regulation of rna metabolic processGO:0051253480.017
regulation of neurotransmitter transportGO:005158810.017
erk1 and erk2 cascadeGO:007037140.016
mitochondrial transportGO:000683920.016
autophagyGO:000691440.016
multicellular organismal homeostasisGO:0048871290.016
regulation of response to biotic stimulusGO:000283120.016
divalent inorganic cation homeostasisGO:0072507220.016
behaviorGO:0007610740.016
cellular amino acid metabolic processGO:000652070.016
b cell activationGO:004211320.016
response to hormoneGO:0009725480.016
release of sequestered calcium ion into cytosolGO:005120930.016
regulation of cellular protein metabolic processGO:0032268520.016
apical junction assemblyGO:004329710.015
developmental growth involved in morphogenesisGO:0060560860.015
regulation of mrna splicing via spliceosomeGO:004802430.015
negative regulation of intracellular protein transportGO:009031730.015
leukocyte homeostasisGO:000177620.015
epibolyGO:0090504410.015
response to bacteriumGO:0009617580.015
intracellular signal transductionGO:0035556850.015
post embryonic morphogenesisGO:000988640.015
rho protein signal transductionGO:000726650.015
negative regulation of cell deathGO:0060548600.015
carboxylic acid metabolic processGO:0019752220.015
single fertilizationGO:000733830.015
actin filament organizationGO:0007015150.015
response to lipidGO:0033993600.015
regulation of gtpase activityGO:004308720.015
carbohydrate derivative metabolic processGO:1901135610.015
nuclear exportGO:005116810.015
establishment of endothelial barrierGO:006102830.015
nucleobase containing compound catabolic processGO:0034655150.015
regulation of multicellular organism growthGO:004001440.015
peptidyl serine modificationGO:001820920.015
oxoacid metabolic processGO:0043436310.014
camera type eye developmentGO:00430102220.014
positive regulation of gliogenesisGO:001401520.014
germ line stem cell maintenanceGO:003071820.014
regulation of metal ion transportGO:001095940.014
negative regulation of protein localization to nucleusGO:190018120.014
regulation of programmed cell deathGO:00430671010.014
regulation of cell developmentGO:00602841000.014
cellular component disassemblyGO:002241110.014
myeloid cell differentiationGO:0030099860.014
positive regulation of map kinase activityGO:004340630.014
positive regulation of gene expressionGO:0010628710.014
specification of axis polarityGO:006500140.014
dorsal ventral neural tube patterningGO:002190410.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
chemotaxisGO:00069351040.014
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
digestive system processGO:002260090.014
regionalizationGO:00030022740.014
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.014
cell cell junction organizationGO:0045216100.014
cellular response to extracellular stimulusGO:003166820.014
cognitionGO:005089010.014
regulation of photoreceptor cell differentiationGO:004653220.014
negative regulation of cytoplasmic transportGO:190365020.014
organelle localizationGO:0051640490.014
vasculature developmentGO:00019442780.014
pole plasm assemblyGO:000731540.014
post golgi vesicle mediated transportGO:000689210.014
actin filament based movementGO:003004810.013
positive regulation of translationGO:004572710.013
negative regulation of metabolic processGO:0009892860.013
chemical homeostasisGO:0048878490.013
positive regulation of phosphorus metabolic processGO:0010562210.013
regulation of neural precursor cell proliferationGO:200017730.013
regulation of exocytosisGO:001715710.013
negative regulation of signal transductionGO:0009968940.013
urogenital system developmentGO:0001655970.013
primary neural tube formationGO:001402010.013
posterior lateral line system developmentGO:0048915460.013
regulation of sequestering of calcium ionGO:005128240.013
rna export from nucleusGO:000640510.013
cellular protein localizationGO:0034613200.013
multi organism processGO:00517041340.013
prevention of polyspermyGO:006046810.013
regulation of mitotic cell cycleGO:0007346250.013
immune effector processGO:0002252230.013
sensory system developmentGO:0048880760.013
muscle contractionGO:0006936180.013
positive regulation of chromosome organizationGO:200125210.013
wound healingGO:0042060900.013
cellular response to oxygen levelsGO:007145310.013
response to endogenous stimulusGO:0009719830.013
cellular nitrogen compound catabolic processGO:0044270150.013
sequestering of calcium ionGO:005120830.013
regulation of growth rateGO:004000910.013
regulation of inflammatory responseGO:005072720.013
single organism biosynthetic processGO:0044711710.013
histone modificationGO:0016570200.012
hormone transportGO:000991420.012

rac1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.111
nervous system diseaseDOID:86300.055
breast cancerDOID:161200.029
cancerDOID:16200.029
organ system cancerDOID:005068600.029
disease of cellular proliferationDOID:1456600.029
thoracic cancerDOID:509300.029
colon carcinomaDOID:152000.014
large intestine cancerDOID:567200.014
colon cancerDOID:21900.014
intestinal cancerDOID:1015500.014
gastrointestinal system cancerDOID:311900.014
colorectal cancerDOID:925600.014
musculoskeletal system diseaseDOID:1700.014