Danio rerio

8 known processes

tiparp

TCDD-inducible poly(ADP-ribose) polymerase

(Aliases: sb:cb841,wu:fc03g05,fc03g05,zgc:153056,MGC153056,si:dkey-33k14.4)

tiparp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
blood vessel developmentGO:00015682460.338
Mouse
cellular component morphogenesisGO:00329893360.224
blood vessel morphogenesisGO:00485142160.190
Mouse
cellular macromolecule metabolic processGO:00442603910.178
Mouse
positive regulation of catabolic processGO:000989640.157
Human
signal transductionGO:00071654550.149
Mouse
angiogenesisGO:00015251580.141
apoptotic processGO:00069151160.136
vasculature developmentGO:00019442780.131
Mouse
ameboidal type cell migrationGO:00016671430.105
regulation of metabolic processGO:00192223590.101
Human
regulation of macromolecule metabolic processGO:00602553170.098
Human
epithelial cell differentiationGO:00308551160.097
positive regulation of cellular processGO:00485222010.086
single organism localizationGO:19025782250.081
regulation of rna metabolic processGO:00512522240.074
regulation of erk1 and erk2 cascadeGO:007037240.074
regulation of anatomical structure morphogenesisGO:00226031300.072
regulation of nitrogen compound metabolic processGO:00511712510.071
organic cyclic compound biosynthetic processGO:19013622230.070
nucleic acid metabolic processGO:00903042440.070
regulation of cell communicationGO:00106462320.068
eye developmentGO:00016542770.067
cellular aromatic compound metabolic processGO:00067252950.066
ventricular cardiac muscle tissue developmentGO:000322930.064
positive regulation of transportGO:005105020.064
negative regulation of blood vessel endothelial cell migrationGO:004353710.063
response to organic substanceGO:00100331530.063
Human
cellular component movementGO:00069283350.062
positive regulation of cellular catabolic processGO:003133130.061
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.060
Mouse
aromatic compound biosynthetic processGO:00194382170.060
regulation of cellular response to growth factor stimulusGO:0090287350.059
larval developmentGO:000216420.059
regulation of cellular macromolecule biosynthetic processGO:20001122220.058
regulation of protein complex assemblyGO:004325430.056
nucleobase containing compound metabolic processGO:00061392740.056
regulation of signalingGO:00230512350.056
extracellular structure organizationGO:0043062270.055
regulation of signal transductionGO:00099662250.054
intracellular signal transductionGO:0035556850.054
heart developmentGO:00075073130.054
sensory organ developmentGO:00074233930.053
compound eye developmentGO:004874920.053
cellular component biogenesisGO:00440851780.052
rna metabolic processGO:00160702190.052
regulation of programmed cell deathGO:00430671010.051
regulation of muscle contractionGO:000693730.051
nucleobase containing compound biosynthetic processGO:00346542050.049
embryonic heart tube developmentGO:00350501330.049
programmed cell deathGO:00125011190.049
regulation of skeletal muscle fiber developmentGO:004874220.048
positive regulation of apoptotic signaling pathwayGO:200123510.048
cell migrationGO:00164772370.048
sensory organ morphogenesisGO:00905962000.047
deathGO:00162651210.047
multicellular organismal metabolic processGO:004423620.047
Mouse
response to uvGO:000941130.046
phosphatidylinositol 3 kinase signalingGO:001406520.046
embryonic organ developmentGO:00485683810.045
negative regulation of cell communicationGO:0010648960.045
negative regulation of cellular processGO:00485232830.044
cellular response to chemical stimulusGO:00708871570.044
cellular nitrogen compound biosynthetic processGO:00442712180.043
heterocycle biosynthetic processGO:00181302150.043
regulation of skeletal muscle tissue developmentGO:004864140.042
multicellular organism growthGO:003526440.041
positive regulation of cellular component biogenesisGO:004408930.041
response to chemicalGO:00422213200.041
regulation of striated muscle contractionGO:000694220.040
generation of neuronsGO:00486993850.040
extrinsic apoptotic signaling pathwayGO:009719130.039
cell motilityGO:00488702440.039
regulation of cytokine productionGO:000181730.039
transcription dna templatedGO:00063511810.038
regulation of cellular component movementGO:0051270550.038
localization of cellGO:00516742440.037
protein dephosphorylationGO:000647030.037
embryo development ending in birth or egg hatchingGO:00097922710.037
heterocycle metabolic processGO:00464832900.037
regulation of response to stimulusGO:00485832690.037
regulation of cell deathGO:00109411030.037
ventricular cardiac muscle tissue morphogenesisGO:005501020.036
cellular macromolecule biosynthetic processGO:00346452240.036
Mouse
vasculogenesisGO:0001570410.036
Mouse
cell substrate adhesionGO:003158940.036
multicellular organismal signalingGO:0035637220.036
positive regulation of epithelial cell differentiationGO:003085820.035
cell cycleGO:0007049930.035
regulation of apoptotic processGO:0042981980.035
regulation of cell shapeGO:000836010.035
hypothalamus cell differentiationGO:002197940.035
regulation of metal ion transportGO:001095940.034
morphogenesis of an epitheliumGO:00020093330.034
regulation of myotube differentiationGO:001083020.034
cell fate specificationGO:0001708680.034
cellular nitrogen compound metabolic processGO:00346412900.034
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.033
protein modification processGO:00362111000.033
Mouse
regulation of protein catabolic processGO:004217610.033
Human
cell growthGO:0016049570.033
activation of immune responseGO:000225390.033
regulation of cell fate commitmentGO:0010453220.033
blood vessel endothelial cell migrationGO:0043534180.032
response to growth factorGO:0070848390.032
gene expressionGO:00104672520.032
Human
regulation of primary metabolic processGO:00800903110.032
Human
anion transportGO:0006820380.032
embryonic hemopoiesisGO:0035162530.031
regulation of cell migrationGO:0030334400.031
organelle organizationGO:00069962270.031
positive regulation of cytoskeleton organizationGO:005149530.031
single organism cell adhesionGO:0098602290.031
response to drugGO:004249330.030
positive regulation of purine nucleotide catabolic processGO:003312310.030
regulation of epithelial cell proliferationGO:005067830.030
negative regulation of signal transductionGO:0009968940.030
circulatory system processGO:0003013870.030
cellular response to growth factor stimulusGO:0071363390.029
nitrogen compound metabolic processGO:00068073190.029
Mouse
negative regulation of metabolic processGO:0009892860.029
Human
regulation of nucleic acid templated transcriptionGO:19035062130.029
negative regulation of signalingGO:0023057960.029
stem cell fate commitmentGO:004886510.029
negative regulation of response to stimulusGO:00485851040.029
cellular response to hypoxiaGO:007145610.028
biological adhesionGO:0022610400.028
retina development in camera type eyeGO:00600411460.028
protein metabolic processGO:00195381830.028
Human Mouse
cardiac conductionGO:006133730.028
single organism organelle organizationGO:19025891990.028
positive regulation of cyclin dependent protein serine threonine kinase activityGO:004573710.028
cellular response to oxygen levelsGO:007145310.028
mesenchyme developmentGO:00604851270.028
long chain fatty acid metabolic processGO:000167610.028
rna biosynthetic processGO:00327741810.027
adherens junction organizationGO:003433240.027
inositol lipid mediated signalingGO:004801720.027
lamellipodium assemblyGO:003003210.026
locomotionGO:00400113130.026
digestive tract morphogenesisGO:00485462310.026
regulation of embryonic developmentGO:0045995470.026
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.026
myeloid cell differentiationGO:0030099860.026
skeletal muscle fiber developmentGO:0048741350.026
camera type eye developmentGO:00430102220.025
cellular response to radiationGO:007147840.025
chordate embryonic developmentGO:00430092710.025
cellular response to nutrient levelsGO:003166920.025
eye morphogenesisGO:00485921440.025
single organism metabolic processGO:00447102170.024
Mouse
actin cytoskeleton organizationGO:0030036630.024
regulation of gene expressionGO:00104682650.024
Human
cell deathGO:00082191210.024
response to vitaminGO:003327330.024
regulation of localizationGO:00328791040.024
post embryonic organ developmentGO:004856940.024
negative regulation of kinase activityGO:003367340.023
regulation of developmental processGO:00507932470.023
cell morphogenesis involved in differentiationGO:00009041950.023
regulation of bindingGO:005109830.023
organic cyclic compound metabolic processGO:19013603010.023
Mouse
heart morphogenesisGO:00030071560.023
hemopoiesisGO:00300971830.023
Mouse
cell morphogenesisGO:00009022890.023
response to nutrientGO:000758430.022
positive regulation of nucleoside metabolic processGO:004597910.022
regulation of multicellular organismal developmentGO:20000262230.022
ear morphogenesisGO:0042471640.022
melanocyte differentiationGO:0030318260.022
lamellipodium organizationGO:009758110.022
positive regulation of apoptotic processGO:0043065290.022
growthGO:00400071740.022
morphogenesis of an epithelial sheetGO:0002011490.022
single organismal cell cell adhesionGO:0016337290.022
cellular component disassemblyGO:002241110.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
regulation of multicellular organismal processGO:00512392770.022
ion transportGO:00068111140.021
stem cell proliferationGO:007208940.021
endothelial cell migrationGO:0043542190.021
establishment of localizationGO:00512342440.021
agingGO:000756820.021
apoptotic signaling pathwayGO:0097190230.021
meiotic nuclear divisionGO:000712640.021
regulation of multicellular organism growthGO:004001440.021
positive regulation of nucleotide catabolic processGO:003081310.021
cell cycle g2 m phase transitionGO:004483940.020
rna processingGO:0006396250.020
positive regulation of macromolecule metabolic processGO:0010604930.020
Human
positive regulation of cell cycleGO:004578730.020
regulation of cell growthGO:0001558290.020
cellular component assemblyGO:00226071700.020
odontogenesis of dentin containing toothGO:004247510.020
amino acid transportGO:000686520.020
regulation of cell motilityGO:2000145460.020
formation of primary germ layerGO:0001704620.020
mitochondrion organizationGO:000700540.020
positive regulation of programmed cell deathGO:0043068290.020
regulation of protein polymerizationGO:003227120.020
immune system developmentGO:00025201910.020
Mouse
regulation of mrna processingGO:005068430.020
regulation of blood circulationGO:1903522320.020
digestive tract developmentGO:00485652650.019
positive regulation of response to stimulusGO:0048584800.019
regulation of biological qualityGO:00650082630.019
Mouse
endocrine hormone secretionGO:006098620.019
regulation of cellular metabolic processGO:00313233200.019
negative regulation of cytokine productionGO:000181810.019
negative regulation of chromosome organizationGO:200125110.019
regulation of meiotic cell cycleGO:005144510.019
cell projection morphogenesisGO:00488582440.019
macromolecule biosynthetic processGO:00090592270.019
Mouse
response to carbohydrateGO:000974330.019
regulation of stem cell proliferationGO:007209120.019
g2 m transition of mitotic cell cycleGO:000008640.019
tissue migrationGO:0090130370.019
phosphorus metabolic processGO:00067931090.019
negative regulation of protein complex assemblyGO:003133310.019
cellular biosynthetic processGO:00442492860.018
Mouse
keratinocyte differentiationGO:003021600.018
lipid storageGO:001991510.018
regulation of gtp catabolic processGO:003312420.018
synaptic growth at neuromuscular junctionGO:005112420.018
complement activationGO:000695630.018
regulation of locomotionGO:0040012550.018
cell surface receptor signaling pathwayGO:00071663250.018
Mouse
endoderm developmentGO:0007492490.018
negative regulation of dna metabolic processGO:005105340.018
regulation of stem cell differentiationGO:200073640.018
regulation of nucleoside metabolic processGO:000911820.017
protein polymerizationGO:005125840.017
actin filament based processGO:0030029640.017
heart processGO:0003015710.017
female sex differentiationGO:004666040.017
Mouse
transportGO:00068102200.017
positive regulation of gtp catabolic processGO:003312610.017
cellular response to decreased oxygen levelsGO:003629410.017
single organism transportGO:00447652060.017
regulation of angiogenesisGO:0045765260.017
negative regulation of histone modificationGO:003105710.017
cellular response to organic substanceGO:00713101050.017
Human
carboxylic acid metabolic processGO:0019752220.017
regulation of vasculature developmentGO:1901342330.017
amine metabolic processGO:000930820.017
sex determinationGO:000753010.017
positive regulation of canonical wnt signaling pathwayGO:009026340.017
regulation of rna biosynthetic processGO:20011412130.017
regulation of cell fate specificationGO:0042659200.017
cell cycle arrestGO:000705010.016
blood circulationGO:0008015870.016
peptidyl lysine acetylationGO:001839420.016
cellular amino acid metabolic processGO:000652070.016
protein complex disassemblyGO:004324110.016
regulation of molecular functionGO:0065009700.016
rna 3 end processingGO:003112320.016
erk1 and erk2 cascadeGO:007037140.016
neuron differentiationGO:00301823530.016
regulation of gtpase activityGO:004308720.016
positive regulation of biological processGO:00485182530.016
Human
regulation of protein bindingGO:004339330.016
regulation of purine nucleotide catabolic processGO:003312120.016
camera type eye morphogenesisGO:00485931080.016
protein stabilizationGO:005082120.016
positive regulation of protein complex assemblyGO:003133420.016
cell part morphogenesisGO:00329902460.016
regulation of epithelial to mesenchymal transitionGO:001071730.016
male meiosisGO:000714020.016
negative regulation of mitosisGO:004583930.016
somatic stem cell maintenanceGO:003501910.016
appendage developmentGO:0048736800.016
nucleic acid templated transcriptionGO:00976591810.016
response to endogenous stimulusGO:0009719830.016
positive regulation of gtpase activityGO:004354710.015
biosynthetic processGO:00090582940.015
Mouse
mitotic cell cycle processGO:1903047480.015
primitive hemopoiesisGO:0060215270.015
positive regulation of macromolecule biosynthetic processGO:0010557590.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
gtp catabolic processGO:000618420.015
dorsal ventral pattern formationGO:00099531250.015
inner ear morphogenesisGO:0042472630.015
regulation of protein ubiquitinationGO:003139630.015
stress fiber assemblyGO:004314950.015
cellular response to retinoic acidGO:007130010.015
tube morphogenesisGO:00352393490.015
enzyme linked receptor protein signaling pathwayGO:00071671060.015
Mouse
positive regulation of molecular functionGO:0044093330.015
endodermal cell fate specificationGO:0001714170.015
brain developmentGO:00074202930.015
negative regulation of cell migrationGO:0030336170.015
organic acid metabolic processGO:0006082310.014
signal transduction in absence of ligandGO:003803410.014
meiosis iGO:000712710.014
regulation of cellular protein catabolic processGO:190336210.014
negative regulation of biological processGO:00485193040.014
Human
gtp metabolic processGO:004603940.014
cellular response to starvationGO:000926710.014
regulation of dendrite morphogenesisGO:004881430.014
cellular response to external stimulusGO:007149620.014
regulation of fibroblast growth factor receptor signaling pathwayGO:0040036200.014
positive regulation of cellular metabolic processGO:0031325940.014
axonogenesisGO:00074091520.014
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.014
regulation of cellular amino acid metabolic processGO:000652100.014
gastrulationGO:00073692080.014
regulation of transporter activityGO:003240920.014
pectoral fin developmentGO:0033339500.014
multicellular organismal macromolecule metabolic processGO:004425920.014
forebrain regionalizationGO:002187140.013
primary neural tube formationGO:001402010.013
negative regulation of cell motilityGO:2000146170.013
regulation of cellular biosynthetic processGO:00313262450.013
regulation of nucleotide catabolic processGO:003081120.013
cell fate commitment involved in formation of primary germ layerGO:0060795260.013
head developmentGO:00603223030.013
Mouse
macromolecular complex disassemblyGO:003298410.013
positive regulation of translationGO:004572710.013
somatic muscle developmentGO:000752540.013
cardiac ventricle developmentGO:000323190.013
regulation of protein transportGO:005122330.013
positive regulation of gene expressionGO:0010628710.013
neuron deathGO:0070997210.013
adult behaviorGO:003053420.013
digestive system developmentGO:00551232890.013
convergent extensionGO:00600261180.013
sprouting angiogenesisGO:0002040530.013
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.013
nuclear exportGO:005116810.013
microtubule based processGO:0007017600.013
microtubule organizing center organizationGO:003102310.013
positive regulation of epithelial cell migrationGO:001063420.013
embryonic limb morphogenesisGO:003032620.013
action potentialGO:0001508190.013
ear developmentGO:00435831270.013
regulation of carbohydrate metabolic processGO:000610940.012
gland developmentGO:00487321430.012
negative regulation of nuclear divisionGO:005178430.012
mesenchymal cell developmentGO:0014031780.012
mesoderm developmentGO:0007498880.012
transcription elongation from rna polymerase ii promoterGO:000636830.012
cardiac ventricle morphogenesisGO:000320870.012
regulation of cell developmentGO:00602841000.012
regulation of organ growthGO:004662030.012
cellular response to extracellular stimulusGO:003166820.012
dna biosynthetic processGO:007189730.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
spindle assemblyGO:005122520.012
response to monosaccharideGO:003428430.012
dna templated transcription elongationGO:000635430.012
response to stressGO:00069502630.012
regulation of protein modification by small protein conjugation or removalGO:190332030.012
osteoclast differentiationGO:003031610.012
cell projection organizationGO:00300302840.012
development of primary female sexual characteristicsGO:004654540.012
Mouse
positive regulation of stress activated mapk cascadeGO:003287430.012
female gonad developmentGO:000858540.012
Mouse
regulation of system processGO:0044057400.012
ectodermal cell fate specificationGO:000171520.012
extracellular matrix organizationGO:0030198270.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
negative regulation of map kinase activityGO:004340720.012
regulation of histone deacetylationGO:003106320.012
small molecule metabolic processGO:0044281770.012
protein activation cascadeGO:007237660.012
regulation of transcription dna templatedGO:00063552130.012
response to unfolded proteinGO:000698620.012
cell cycle g1 s phase transitionGO:004484310.012
macromolecule modificationGO:00434121110.012
Mouse
developmental growth involved in morphogenesisGO:0060560860.012
protein complex subunit organizationGO:0071822460.012
negative regulation of mapk cascadeGO:004340940.012
cellular localizationGO:0051641970.012
developmental programmed cell deathGO:001062340.012
negative regulation of epithelial cell proliferationGO:005068010.011
cellular carbohydrate metabolic processGO:004426240.011
positive regulation of cell divisionGO:005178120.011
regulation of heart contractionGO:0008016320.011
regulation of cellular amine metabolic processGO:003323800.011
cellular monovalent inorganic cation homeostasisGO:003000420.011
regulation of cell activationGO:005086510.011
collateral sproutingGO:004866890.011
guanosine containing compound catabolic processGO:190106920.011
cellular protein metabolic processGO:00442671290.011
Mouse
regulation of intracellular protein transportGO:003315730.011
regulation of gastrulationGO:0010470240.011
response to oxygen levelsGO:0070482250.011
regulation of glial cell proliferationGO:006025140.011
cellular sodium ion homeostasisGO:000688310.011
positive regulation of embryonic developmentGO:004001930.011
regulation of cardiac muscle contractionGO:005511720.011
regulation of actin filament based movementGO:190311510.011
sympathetic nervous system developmentGO:004848530.011
lateral inhibitionGO:004633110.011
stem cell maintenanceGO:001982740.011
g1 s transition of mitotic cell cycleGO:000008210.011
extracellular matrix assemblyGO:008502910.011
maintenance of locationGO:005123540.011
cellular response to fatty acidGO:007139830.011
regionalizationGO:00030022740.011
cellular amine metabolic processGO:004410620.011
regulation of rho protein signal transductionGO:003502320.011
cell adhesionGO:0007155400.011
cellular response to endogenous stimulusGO:0071495680.011
regulation of reproductive processGO:200024140.011
positive regulation of developmental processGO:0051094500.011
endodermal cell differentiationGO:0035987190.011
lymphangiogenesisGO:0001946250.011
negative regulation of collateral sproutingGO:004867120.011
regulation of cell substrate adhesionGO:001081010.011
positive regulation of cellular amine metabolic processGO:003324000.011
positive regulation of cytokine productionGO:000181920.011
regulation of multicellular organismal metabolic processGO:004424620.010
proteasomal protein catabolic processGO:001049820.010
negative regulation of collateral sprouting of intact axon in response to injuryGO:004868520.010
interspecies interaction between organismsGO:004441940.010
response to metal ionGO:0010038340.010
macromolecular complex subunit organizationGO:0043933740.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
cellular protein modification processGO:00064641000.010
Mouse
negative regulation of cellular component organizationGO:0051129160.010
developmental growthGO:00485891660.010
negative regulation of intracellular signal transductionGO:1902532220.010
adherens junction assemblyGO:003433310.010
angioblast cell differentiationGO:003577920.010
collagen biosynthetic processGO:003296420.010
positive regulation of cell deathGO:0010942290.010
response to fibroblast growth factorGO:0071774220.010
protein deacetylationGO:000647630.010
protein complex localizationGO:003150310.010
collagen metabolic processGO:003296320.010
phosphate containing compound metabolic processGO:00067961080.010
cytokine metabolic processGO:004210710.010
regulation of mrna splicing via spliceosomeGO:004802430.010

tiparp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
musculoskeletal system diseaseDOID:1700.042
nervous system diseaseDOID:86300.040
disease of cellular proliferationDOID:1456600.036
cancerDOID:16200.036
myopathyDOID:42300.025
muscle tissue diseaseDOID:6600.025
muscular diseaseDOID:008000000.025
cardiovascular system diseaseDOID:128700.025
cardiomyopathyDOID:005070000.025
intrinsic cardiomyopathyDOID:006003600.025
heart diseaseDOID:11400.025
organ system cancerDOID:005068600.022
gastrointestinal system cancerDOID:311900.020