Danio rerio

0 known processes

xrn1

5'-3' exoribonuclease 1

(Aliases: MGC63635,wu:fk92c07,zgc:63635)

xrn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.316
chordate embryonic developmentGO:00430092710.231
single organism nuclear importGO:190259330.213
cellular macromolecule metabolic processGO:00442603910.180
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.173
organelle assemblyGO:00709251100.157
embryonic skeletal system developmentGO:0048706970.149
nucleocytoplasmic transportGO:000691340.131
protein import into nucleusGO:000660630.125
ubiquitin dependent protein catabolic processGO:000651130.100
establishment of localizationGO:00512342440.093
modification dependent macromolecule catabolic processGO:004363230.093
cellular protein catabolic processGO:004425740.091
nuclear transportGO:005116940.091
protein localization to nucleusGO:003450430.090
protein targeting to nucleusGO:004474430.089
agingGO:000756820.087
skeletal system developmentGO:00015011810.084
positive regulation of catabolic processGO:000989640.083
cellular biosynthetic processGO:00442492860.081
embryonic organ morphogenesisGO:00485622740.076
transportGO:00068102200.072
regulation of multicellular organism growthGO:004001440.072
heart developmentGO:00075073130.070
negative regulation of protein phosphorylationGO:000193340.068
proteasomal protein catabolic processGO:001049820.066
embryo development ending in birth or egg hatchingGO:00097922710.066
negative regulation of protein kinase activityGO:000646940.064
meiotic nuclear divisionGO:000712640.060
cellular nitrogen compound metabolic processGO:00346412900.060
regulation of multicellular organismal processGO:00512392770.058
modification dependent protein catabolic processGO:001994130.058
embryonic cranial skeleton morphogenesisGO:0048701900.056
establishment of protein localization to organelleGO:007259440.053
synaptic vesicle transportGO:004848910.050
proteolysis involved in cellular protein catabolic processGO:005160330.050
embryonic skeletal system morphogenesisGO:0048704930.049
embryonic organ developmentGO:00485683810.049
cellular macromolecule biosynthetic processGO:00346452240.048
heterocycle biosynthetic processGO:00181302150.048
nuclear importGO:005117030.047
regulation of establishment of protein localizationGO:007020140.046
regulation of synapse organizationGO:005080730.045
regulation of stem cell differentiationGO:200073640.043
skeletal system morphogenesisGO:00487051020.043
regulation of rna biosynthetic processGO:20011412130.042
regulation of reproductive processGO:200024140.042
single organism localizationGO:19025782250.042
apoptotic process involved in developmentGO:190274220.042
regulation of biological qualityGO:00650082630.042
nucleic acid metabolic processGO:00903042440.041
synaptic growth at neuromuscular junctionGO:005112420.041
positive regulation of cellular catabolic processGO:003133130.041
cellular nitrogen compound biosynthetic processGO:00442712180.040
single organism transportGO:00447652060.040
embryonic viscerocranium morphogenesisGO:0048703520.040
extrinsic apoptotic signaling pathwayGO:009719130.040
negative regulation of kinase activityGO:003367340.039
cellular component movementGO:00069283350.038
protein importGO:001703830.038
establishment of synaptic vesicle localizationGO:009748010.037
gtp catabolic processGO:000618420.037
heterocycle metabolic processGO:00464832900.036
stem cell maintenanceGO:001982740.036
regulation of localizationGO:00328791040.036
regulation of nucleocytoplasmic transportGO:004682220.036
response to stressGO:00069502630.035
cellular localizationGO:0051641970.035
regulation of synaptic growth at neuromuscular junctionGO:000858210.034
regulation of purine nucleotide catabolic processGO:003312120.033
cartilage developmentGO:0051216960.033
response to topologically incorrect proteinGO:003596620.033
response to external stimulusGO:00096052640.033
mitochondrion organizationGO:000700540.032
adult behaviorGO:003053420.032
regulation of synapse assemblyGO:005196330.032
regulation of circadian rhythmGO:004275240.032
synaptic vesicle localizationGO:009747910.032
regulation of macromolecule metabolic processGO:00602553170.031
locomotor rhythmGO:004547530.031
regulation of intracellular protein transportGO:003315730.031
cellular response to nutrient levelsGO:003166920.031
sensory organ developmentGO:00074233930.030
embryonic heart tube developmentGO:00350501330.030
regulation of protein targetingGO:190353320.030
protein complex localizationGO:003150310.030
cell surface receptor signaling pathwayGO:00071663250.030
regulation of developmental processGO:00507932470.029
regulation of cell communicationGO:00106462320.029
positive regulation of transportGO:005105020.029
entrainment of circadian clockGO:000964920.028
locomotionGO:00400113130.028
lipid storageGO:001991510.028
phagocytosisGO:000690930.028
connective tissue developmentGO:0061448990.028
regulation of protein transportGO:005122330.028
response to other organismGO:0051707970.027
positive regulation of nucleoside metabolic processGO:004597910.027
gene expressionGO:00104672520.027
er nucleus signaling pathwayGO:000698420.026
peptidyl serine modificationGO:001820920.026
organic cyclic compound metabolic processGO:19013603010.026
specification of symmetryGO:00097992040.026
determination of left right symmetryGO:00073681790.026
phosphate containing compound metabolic processGO:00067961080.025
regulation of nucleoside metabolic processGO:000911820.025
regulation of protein localization to nucleusGO:190018020.025
regulation of metabolic processGO:00192223590.025
production of molecular mediator of immune responseGO:000244020.025
negative regulation of biological processGO:00485193040.025
multicellular organism growthGO:003526440.025
response to external biotic stimulusGO:0043207970.025
central nervous system developmentGO:00074173870.024
regulation of cellular biosynthetic processGO:00313262450.024
embryonic heart tube morphogenesisGO:00031431080.024
erk1 and erk2 cascadeGO:007037140.024
regulation of cytoplasmic transportGO:190364940.024
gtp metabolic processGO:004603940.024
peptidyl serine phosphorylationGO:001810510.023
protein metabolic processGO:00195381830.023
meiotic cell cycle processGO:190304630.023
positive regulation of gtp catabolic processGO:003312610.023
regulation of gtp catabolic processGO:003312420.023
regulation of cellular carbohydrate metabolic processGO:001067540.023
amine metabolic processGO:000930820.023
positive regulation of biological processGO:00485182530.023
immune system processGO:00023762410.023
response to biotic stimulusGO:0009607970.022
cell motilityGO:00488702440.022
regulation of protein import into nucleusGO:004230620.022
regulation of epithelial cell proliferationGO:005067830.022
positive regulation of nucleotide catabolic processGO:003081310.022
response to chemicalGO:00422213200.021
establishment of rna localizationGO:005123630.021
embryonic skeletal joint morphogenesisGO:006027230.021
positive regulation of muscle cell differentiationGO:005114910.021
negative regulation of multicellular organismal processGO:0051241690.021
negative regulation of nuclear divisionGO:005178430.021
response to drugGO:004249330.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
single organism organelle organizationGO:19025891990.021
somitogenesisGO:0001756870.021
regulation of nucleotide catabolic processGO:003081120.021
negative regulation of mapk cascadeGO:004340940.020
cellular response to chemical stimulusGO:00708871570.020
regulation of cytokine productionGO:000181730.020
b cell activationGO:004211320.020
positive regulation of cellular component biogenesisGO:004408930.020
protein dephosphorylationGO:000647030.020
cellular response to starvationGO:000926710.020
regulation of gtpase activityGO:004308720.020
cell cycle arrestGO:000705010.020
organic substance biosynthetic processGO:19015762890.020
negative regulation of developmental processGO:0051093650.020
defense responseGO:0006952470.020
determination of bilateral symmetryGO:00098552040.020
neurotransmitter secretionGO:000726920.020
heart morphogenesisGO:00030071560.020
regulation of cellular metabolic processGO:00313233200.020
positive regulation of map kinase activityGO:004340630.020
response to organic substanceGO:00100331530.020
defense response to other organismGO:0098542330.019
protein stabilizationGO:005082120.019
stem cell developmentGO:0048864820.019
neurotransmitter transportGO:000683620.019
membrane invaginationGO:001032410.019
regulation of protein catabolic processGO:004217610.019
stem cell proliferationGO:007208940.019
positive regulation of purine nucleotide catabolic processGO:003312310.019
brain developmentGO:00074202930.019
golgi vesicle transportGO:004819330.019
guanosine containing compound catabolic processGO:190106920.018
regulation of cellular amine metabolic processGO:003323800.018
stem cell differentiationGO:00488631170.018
angiogenesisGO:00015251580.018
biosynthetic processGO:00090582940.018
cellular component morphogenesisGO:00329893360.018
nitrogen compound metabolic processGO:00068073190.018
negative regulation of defense responseGO:003134820.018
organic substance transportGO:0071702580.018
establishment of vesicle localizationGO:0051650240.017
maintenance of locationGO:005123540.017
macromolecule localizationGO:0033036540.017
meiosis iGO:000712710.017
negative regulation of synapse assemblyGO:005196420.017
catabolic processGO:0009056320.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.017
renal tubule morphogenesisGO:006133310.017
regulation of programmed cell deathGO:00430671010.017
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.017
regulation of organelle assemblyGO:190211540.017
synaptic vesicle endocytosisGO:004848810.017
cellular response to extracellular stimulusGO:003166820.017
post golgi vesicle mediated transportGO:000689210.017
organelle fusionGO:004828430.017
guanosine containing compound metabolic processGO:190106840.017
rna metabolic processGO:00160702190.017
vesicle localizationGO:0051648270.017
nucleobase containing compound biosynthetic processGO:00346542050.017
blood vessel morphogenesisGO:00485142160.017
muscle cell differentiationGO:00426921390.016
regulation of cellular protein catabolic processGO:190336210.016
response to unfolded proteinGO:000698620.016
determination of heart left right asymmetryGO:00613711170.016
negative regulation of programmed cell deathGO:0043069580.016
cellular response to external stimulusGO:007149620.016
regulation of catalytic activityGO:0050790550.016
regulation of carbohydrate metabolic processGO:000610940.016
signal transductionGO:00071654550.016
regulation of protein complex assemblyGO:004325430.016
endoplasmic reticulum unfolded protein responseGO:003096820.016
regulation of extrinsic apoptotic signaling pathwayGO:200123630.016
cellular macromolecule catabolic processGO:0044265120.016
regulation of cellular macromolecule biosynthetic processGO:20001122220.016
regulation of epithelial to mesenchymal transitionGO:001071730.016
cellular amide metabolic processGO:004360340.016
protein secretionGO:000930610.015
mitochondrial transportGO:000683920.015
negative regulation of reproductive processGO:200024230.015
regulation of response to stimulusGO:00485832690.015
tube morphogenesisGO:00352393490.015
compound eye developmentGO:004874920.015
regulation of cell activationGO:005086510.015
generation of neuronsGO:00486993850.015
macromolecule biosynthetic processGO:00090592270.015
negative regulation of cellular processGO:00485232830.015
organonitrogen compound metabolic processGO:1901564740.015
negative regulation of molecular functionGO:0044092230.015
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
cell morphogenesisGO:00009022890.015
neuron developmentGO:00486662620.015
negative regulation of epithelial cell proliferationGO:005068010.015
negative regulation of catabolic processGO:000989530.015
epithelial tube morphogenesisGO:00605621480.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
cellular amino acid metabolic processGO:000652070.014
cellular aromatic compound metabolic processGO:00067252950.014
ameboidal type cell migrationGO:00016671430.014
cell death in response to oxidative stressGO:003647320.014
organic acid metabolic processGO:0006082310.014
localization of cellGO:00516742440.014
regulation of molecular functionGO:0065009700.014
synaptic target recognitionGO:000803910.014
mesenchyme developmentGO:00604851270.014
immune system developmentGO:00025201910.014
positive regulation of cell cycleGO:004578730.014
regulation of synaptic plasticityGO:004816710.014
rna 3 end processingGO:003112320.014
cellular response to topologically incorrect proteinGO:003596720.014
heart loopingGO:0001947940.014
cell migration involved in heart developmentGO:0060973220.014
morphogenesis of an epitheliumGO:00020093330.014
cognitionGO:005089010.014
head developmentGO:00603223030.014
positive regulation of oocyte developmentGO:006028210.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
rna localizationGO:000640340.014
regulation of bindingGO:005109830.014
regulation of translational initiationGO:000644610.014
single organism cellular localizationGO:1902580460.013
positive regulation of gtpase activityGO:004354710.013
positive regulation of apoptotic signaling pathwayGO:200123510.013
regulation of erk1 and erk2 cascadeGO:007037240.013
negative regulation of cell communicationGO:0010648960.013
regulation of primary metabolic processGO:00800903110.013
negative regulation of stem cell differentiationGO:200073720.013
negative regulation of cytoplasmic transportGO:190365020.013
cytoskeleton organizationGO:0007010960.013
regulation of cellular component movementGO:0051270550.013
oxoacid metabolic processGO:0043436310.013
muscle structure developmentGO:00610611960.013
regulation of response to biotic stimulusGO:000283120.013
negative regulation of cell differentiationGO:0045596460.013
developmental programmed cell deathGO:001062340.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
neuron remodelingGO:001632210.012
regulation of cellular component organizationGO:0051128860.012
negative regulation of catalytic activityGO:0043086210.012
striated muscle cell developmentGO:00550021080.012
macroautophagyGO:001623610.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
cellular amine metabolic processGO:004410620.012
cellular catabolic processGO:0044248270.012
negative regulation of sequestering of calcium ionGO:005128340.012
translational initiationGO:000641330.012
neuron differentiationGO:00301823530.012
regulation of signalingGO:00230512350.012
phosphorus metabolic processGO:00067931090.012
regulation of stem cell proliferationGO:007209120.012
cellular component assemblyGO:00226071700.012
programmed cell deathGO:00125011190.012
vasculature developmentGO:00019442780.012
regulation of gene expressionGO:00104682650.012
regulation of dendrite developmentGO:005077330.012
regulation of ras gtpase activityGO:003231820.012
regulation of cell shapeGO:000836010.012
establishment of localization in cellGO:0051649770.012
neuronal stem cell maintenanceGO:009715020.012
organelle organizationGO:00069962270.012
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.012
developmental growthGO:00485891660.012
nuclear divisionGO:0000280230.012
centrosome cycleGO:000709810.012
intracellular mrna localizationGO:000829810.012
transcription from rna polymerase ii promoterGO:0006366800.012
regulation of biosynthetic processGO:00098892500.012
maternal determination of anterior posterior axis embryoGO:000835840.012
system processGO:00030081850.011
response to light stimulusGO:0009416460.011
negative regulation of multi organism processGO:004390130.011
peptide transportGO:001583310.011
multi organism processGO:00517041340.011
mrna export from nucleusGO:000640610.011
lateral inhibitionGO:004633110.011
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.011
protein phosphorylationGO:0006468470.011
phagocytosis engulfmentGO:000691110.011
single organism membrane fusionGO:004480120.011
negative regulation of innate immune responseGO:004582420.011
single organism metabolic processGO:00447102170.011
cellular response to stressGO:0033554620.011
phosphorylationGO:0016310690.011
positive regulation of immune effector processGO:000269930.011
liver developmentGO:0001889960.011
post embryonic organ developmentGO:004856940.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
nucleobase containing compound metabolic processGO:00061392740.011
cellular protein modification processGO:00064641000.011
immune effector processGO:0002252230.011
water homeostasisGO:003010440.011
rna biosynthetic processGO:00327741810.011
glial cell proliferationGO:001400940.011
regulation of cell projection assemblyGO:006049140.011
negative regulation of intracellular transportGO:003238730.010
mrna transportGO:005102820.010
positive regulation of nitrogen compound metabolic processGO:0051173690.010
cellular component biogenesisGO:00440851780.010
cellular protein metabolic processGO:00442671290.010
gastrulationGO:00073692080.010
germ line stem cell maintenanceGO:003071820.010
regulation of mrna processingGO:005068430.010
carboxylic acid metabolic processGO:0019752220.010
regulation of response to oxidative stressGO:190288220.010
somatic stem cell maintenanceGO:003501910.010
blood vessel developmentGO:00015682460.010
positive regulation of cell divisionGO:005178120.010
tissue remodelingGO:004877140.010
negative regulation of response to stimulusGO:00485851040.010
anterior posterior pattern specificationGO:00099521520.010

xrn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
myopathyDOID:42300.046
musculoskeletal system diseaseDOID:1700.046
muscular diseaseDOID:008000000.046
muscle tissue diseaseDOID:6600.046
disease of metabolismDOID:001466700.017
cardiovascular system diseaseDOID:128700.010
heart diseaseDOID:11400.010
cardiomyopathyDOID:005070000.010
intrinsic cardiomyopathyDOID:006003600.010