Danio rerio

0 known processes

ttc1

tetratricopeptide repeat domain 1

(Aliases: zgc:101838,im:7143277)

ttc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.064
larval developmentGO:000216420.062
proteolysis involved in cellular protein catabolic processGO:005160330.046
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.045
positive regulation of transportGO:005105020.045
cellular protein catabolic processGO:004425740.043
modification dependent protein catabolic processGO:001994130.041
cellular nitrogen compound metabolic processGO:00346412900.039
nitrogen compound metabolic processGO:00068073190.039
ubiquitin dependent protein catabolic processGO:000651130.038
mitochondrion organizationGO:000700540.037
cellular macromolecule metabolic processGO:00442603910.036
proteasomal protein catabolic processGO:001049820.036
establishment of protein localization to organelleGO:007259440.035
regulation of cytokine productionGO:000181730.034
regulation of multicellular organism growthGO:004001440.033
negative regulation of protein phosphorylationGO:000193340.032
phagocytosisGO:000690930.032
multicellular organism growthGO:003526440.032
modification dependent macromolecule catabolic processGO:004363230.032
biosynthetic processGO:00090582940.031
meiotic nuclear divisionGO:000712640.031
maintenance of locationGO:005123540.031
amine metabolic processGO:000930820.030
protein acetylationGO:000647320.030
regulation of metabolic processGO:00192223590.029
positive regulation of catabolic processGO:000989640.029
guanosine containing compound metabolic processGO:190106840.028
signal transductionGO:00071654550.028
heterocycle metabolic processGO:00464832900.028
organic cyclic compound metabolic processGO:19013603010.028
autophagyGO:000691440.027
nucleobase containing compound metabolic processGO:00061392740.026
nucleocytoplasmic transportGO:000691340.026
positive regulation of cell cycleGO:004578730.026
cellular biosynthetic processGO:00442492860.026
rna localizationGO:000640340.026
single organism metabolic processGO:00447102170.026
organic substance biosynthetic processGO:19015762890.026
regulation of cellular metabolic processGO:00313233200.026
cell surface receptor signaling pathwayGO:00071663250.026
gene expressionGO:00104672520.025
cellular aromatic compound metabolic processGO:00067252950.025
positive regulation of cellular catabolic processGO:003133130.025
cognitionGO:005089010.025
peptidyl lysine acetylationGO:001839420.025
protein localization to nucleusGO:003450430.025
cellular response to external stimulusGO:007149620.025
single organism nuclear importGO:190259330.025
cellular amine metabolic processGO:004410620.025
regulation of protein transportGO:005122330.025
regulation of protein complex assemblyGO:004325430.025
internal peptidyl lysine acetylationGO:001839320.025
organonitrogen compound metabolic processGO:1901564740.025
regulation of macromolecule metabolic processGO:00602553170.025
gtp catabolic processGO:000618420.024
regulation of nitrogen compound metabolic processGO:00511712510.024
negative regulation of biological processGO:00485193040.024
regulation of metal ion transportGO:001095940.024
regulation of establishment of protein localizationGO:007020140.024
gtp metabolic processGO:004603940.024
lipid storageGO:001991510.024
carboxylic acid catabolic processGO:004639530.024
positive regulation of cellular component biogenesisGO:004408930.024
internal protein amino acid acetylationGO:000647520.023
ribonucleoside monophosphate catabolic processGO:000915840.023
response to drugGO:004249330.023
organic cyclic compound biosynthetic processGO:19013622230.023
endosomal transportGO:001619720.023
cytokinesisGO:000091030.023
protein importGO:001703830.023
i kappab kinase nf kappab signalingGO:000724940.023
guanosine containing compound catabolic processGO:190106920.023
meiotic cell cycle processGO:190304630.023
small molecule metabolic processGO:0044281770.023
regulation of nucleocytoplasmic transportGO:004682220.023
tube morphogenesisGO:00352393490.023
regulation of cellular amino acid metabolic processGO:000652100.023
xenobiotic metabolic processGO:000680540.023
regulation of cellular amine metabolic processGO:003323800.022
regulation of nucleoside metabolic processGO:000911820.022
extrinsic apoptotic signaling pathwayGO:009719130.022
regulation of cytoplasmic transportGO:190364940.022
nuclear transportGO:005116940.022
protein acylationGO:004354330.022
nucleic acid metabolic processGO:00903042440.022
synaptic growth at neuromuscular junctionGO:005112420.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
compound eye developmentGO:004874920.022
nuclear importGO:005117030.022
response to stressGO:00069502630.022
negative regulation of catabolic processGO:000989530.022
morphogenesis of an epitheliumGO:00020093330.022
organic acid catabolic processGO:001605430.022
regulation of protein import into nucleusGO:004230620.022
regulation of meiotic cell cycleGO:005144510.022
exocytosisGO:000688710.021
cell substrate adhesionGO:003158940.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
protein import into nucleusGO:000660630.021
membrane fusionGO:006102520.021
regulation of bindingGO:005109830.021
protein targeting to nucleusGO:004474430.021
nucleoside monophosphate catabolic processGO:000912540.021
cellular response to extracellular stimulusGO:003166820.021
atp catabolic processGO:000620040.021
regulation of autophagyGO:001050630.021
single organism membrane fusionGO:004480120.021
cellular component movementGO:00069283350.021
cellular response to nutrient levelsGO:003166920.021
negative regulation of cellular processGO:00485232830.021
regulation of intracellular protein transportGO:003315730.021
regulation of nucleotide catabolic processGO:003081120.021
regulation of synapse organizationGO:005080730.021
positive regulation of biological processGO:00485182530.021
protein metabolic processGO:00195381830.020
stem cell proliferationGO:007208940.020
regulation of mrna processingGO:005068430.020
organic acid metabolic processGO:0006082310.020
oxoacid metabolic processGO:0043436310.020
regulation of biosynthetic processGO:00098892500.020
regulation of protein localization to nucleusGO:190018020.020
regulation of i kappab kinase nf kappab signalingGO:004312240.020
regulation of primary metabolic processGO:00800903110.020
small molecule catabolic processGO:004428230.020
regulation of protein targetingGO:190353320.020
regulation of protein catabolic processGO:004217610.020
negative regulation of protein kinase activityGO:000646940.020
positive regulation of purine nucleotide catabolic processGO:003312310.020
regulation of cellular biosynthetic processGO:00313262450.020
aromatic compound biosynthetic processGO:00194382170.020
regulation of protein ubiquitinationGO:003139630.020
regulation of gene expressionGO:00104682650.019
organelle fusionGO:004828430.019
cellular carbohydrate metabolic processGO:004426240.019
rna metabolic processGO:00160702190.019
negative regulation of kinase activityGO:003367340.019
immune system processGO:00023762410.019
positive regulation of cytokine productionGO:000181920.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
sensory organ developmentGO:00074233930.019
meiotic chromosome segregationGO:004513230.019
macromolecule biosynthetic processGO:00090592270.019
regulation of neural precursor cell proliferationGO:200017730.019
positive regulation of secretionGO:005104710.019
neuron differentiationGO:00301823530.019
regulation of purine nucleotide catabolic processGO:003312120.019
stem cell maintenanceGO:001982740.019
carboxylic acid metabolic processGO:0019752220.019
negative regulation of protein transportGO:005122430.019
regulation of cell shapeGO:000836010.019
rna biosynthetic processGO:00327741810.019
cellular component morphogenesisGO:00329893360.019
regulation of cellular ketone metabolic processGO:001056570.018
transcription dna templatedGO:00063511810.018
generation of neuronsGO:00486993850.018
heterocycle biosynthetic processGO:00181302150.018
central nervous system developmentGO:00074173870.018
cellular macromolecule biosynthetic processGO:00346452240.018
purine nucleoside monophosphate catabolic processGO:000912840.018
regulation of synaptic plasticityGO:004816710.018
response to external stimulusGO:00096052640.018
cellular amino acid metabolic processGO:000652070.018
regulation of synaptic growth at neuromuscular junctionGO:000858210.018
regulation of synapse assemblyGO:005196330.018
neurotransmitter secretionGO:000726920.018
protein localization to plasma membraneGO:007265910.018
establishment of localizationGO:00512342440.018
positive regulation of i kappab kinase nf kappab signalingGO:004312330.018
symbiosis encompassing mutualism through parasitismGO:004440340.018
regulation of reproductive processGO:200024140.017
positive regulation of dna metabolic processGO:005105410.017
cell part morphogenesisGO:00329902460.017
peptide metabolic processGO:000651810.017
positive regulation of secretion by cellGO:190353210.017
cellular response to starvationGO:000926710.017
adherens junction organizationGO:003433240.017
cytoplasm organizationGO:000702840.017
neurotransmitter transportGO:000683620.017
regulation of cell communicationGO:00106462320.017
regulation of multicellular organismal processGO:00512392770.017
secondary metabolic processGO:001974830.017
nucleobase containing compound biosynthetic processGO:00346542050.017
vasculature developmentGO:00019442780.017
gastrulationGO:00073692080.017
peptidyl serine modificationGO:001820920.017
heart developmentGO:00075073130.017
regulation of neurotransmitter transportGO:005158810.017
chordate embryonic developmentGO:00430092710.017
blood vessel morphogenesisGO:00485142160.017
digestive tract developmentGO:00485652650.017
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.017
cell projection morphogenesisGO:00488582440.017
peptidyl serine phosphorylationGO:001810510.017
eye developmentGO:00016542770.016
angiogenesisGO:00015251580.016
response to uvGO:000941130.016
digestive system developmentGO:00551232890.016
digestive tract morphogenesisGO:00485462310.016
cell morphogenesisGO:00009022890.016
single organism localizationGO:19025782250.016
response to chemicalGO:00422213200.016
transportGO:00068102200.016
regulation of signalingGO:00230512350.016
regulation of gtp catabolic processGO:003312420.016
cellular component disassemblyGO:002241110.016
regulation of response to biotic stimulusGO:000283120.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
cellular protein metabolic processGO:00442671290.016
regulation of gtpase activityGO:004308720.016
positive regulation of nucleoside metabolic processGO:004597910.016
multi organism processGO:00517041340.016
cellular response to oxygen levelsGO:007145310.016
regulation of response to stimulusGO:00485832690.016
positive regulation of gtp catabolic processGO:003312610.016
single organism organelle organizationGO:19025891990.016
regulation of production of molecular mediator of immune responseGO:000270010.016
regulation of rna metabolic processGO:00512522240.016
cell projection organizationGO:00300302840.016
regulation of developmental processGO:00507932470.016
spermatid developmentGO:000728620.016
production of molecular mediator of immune responseGO:000244020.016
regulation of erk1 and erk2 cascadeGO:007037240.016
cellular response to biotic stimulusGO:007121630.016
fertilizationGO:000956630.016
cellular ketone metabolic processGO:0042180110.016
negative regulation of cellular catabolic processGO:003133030.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
positive regulation of cellular amine metabolic processGO:003324000.016
blood vessel developmentGO:00015682460.016
regulation of reactive oxygen species metabolic processGO:200037720.016
protein polyubiquitinationGO:000020940.016
localization of cellGO:00516742440.016
erk1 and erk2 cascadeGO:007037140.016
positive regulation of nucleotide catabolic processGO:003081310.015
locomotionGO:00400113130.015
interspecies interaction between organismsGO:004441940.015
deathGO:00162651210.015
head developmentGO:00603223030.015
mitotic dna integrity checkpointGO:004477440.015
adult behaviorGO:003053420.015
negative regulation of map kinase activityGO:004340720.015
sequestering of calcium ionGO:005120830.015
cell cycle g1 s phase transitionGO:004484310.015
locomotor rhythmGO:004547530.015
golgi vesicle transportGO:004819330.015
spermatid differentiationGO:004851520.015
regulation of signal transductionGO:00099662250.015
intracellular mrna localizationGO:000829810.015
organelle organizationGO:00069962270.015
female sex differentiationGO:004666040.015
nucleic acid templated transcriptionGO:00976591810.015
regulation of macromolecule biosynthetic processGO:00105562250.015
anterior posterior pattern specificationGO:00099521520.015
negative regulation of mapk cascadeGO:004340940.015
cellular response to lipopolysaccharideGO:007122230.015
positive regulation of cellular processGO:00485222010.015
muscle structure developmentGO:00610611960.015
regulation of stem cell proliferationGO:007209120.015
vacuolar transportGO:000703420.015
regulation of mrna splicing via spliceosomeGO:004802430.015
synaptic vesicle localizationGO:009747910.015
positive regulation of gtpase activityGO:004354710.014
single fertilizationGO:000733830.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
monocarboxylic acid catabolic processGO:007232930.014
cell matrix adhesionGO:000716040.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
cellular response to chemical stimulusGO:00708871570.014
cellular response to molecule of bacterial originGO:007121930.014
regulation of cellular protein catabolic processGO:190336210.014
centrosome organizationGO:005129710.014
regionalizationGO:00030022740.014
negative regulation of nucleocytoplasmic transportGO:004682320.014
regulation of cell activationGO:005086510.014
negative regulation of intracellular transportGO:003238730.014
regulation of neurotransmitter secretionGO:004692810.014
multi organism cellular processGO:004476420.014
single organism transportGO:00447652060.014
establishment of synaptic vesicle localizationGO:009748010.014
cell migrationGO:00164772370.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
regulation of calcium ion transportGO:005192420.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
negative regulation of cytoplasmic transportGO:190365020.014
lateral inhibitionGO:004633110.014
regulation of transporter activityGO:003240920.014
synaptic vesicle transportGO:004848910.014
positive regulation of stress activated mapk cascadeGO:003287430.014
rna transportGO:005065820.014
response to glucoseGO:000974930.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
primary neural tube formationGO:001402010.014
cell motilityGO:00488702440.014
macromolecular complex disassemblyGO:003298410.014
cellular amide metabolic processGO:004360340.014
positive regulation of protein complex assemblyGO:003133420.014
regulation of transcription dna templatedGO:00063552130.014
embryo development ending in birth or egg hatchingGO:00097922710.014
response to hexoseGO:000974630.014
response to carbohydrateGO:000974330.013
positive regulation of chromosome organizationGO:200125210.013
nuclear exportGO:005116810.013
cellular response to hypoxiaGO:007145610.013
negative regulation of protein complex assemblyGO:003133310.013
negative regulation of nuclear divisionGO:005178430.013
neuromuscular synaptic transmissionGO:000727420.013
nucleic acid transportGO:005065720.013
actin filament polymerizationGO:003004120.013
specification of symmetryGO:00097992040.013
negative regulation of synapse assemblyGO:005196420.013
regulation of biological qualityGO:00650082630.013
female gonad developmentGO:000858540.013
hemopoiesisGO:00300971830.013
growthGO:00400071740.013
mitochondrial transportGO:000683920.013
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.013
cellular lipid catabolic processGO:004424230.013
regulation of dendrite developmentGO:005077330.013
sleepGO:003043110.013
lipid oxidationGO:003444010.013
neuroblast proliferationGO:000740520.013
positive regulation of cytoskeleton organizationGO:005149530.013
cellular component assemblyGO:00226071700.013
tube closureGO:006060610.013
positive regulation of erk1 and erk2 cascadeGO:007037420.013
g1 s transition of mitotic cell cycleGO:000008210.013
cellular response to decreased oxygen levelsGO:003629410.013
negative regulation of cytokine productionGO:000181810.013
regulation of sequestering of calcium ionGO:005128240.013
positive regulation of immune effector processGO:000269930.013
brain developmentGO:00074202930.013
regulation of chromosome segregationGO:005198310.013
germ line stem cell maintenanceGO:003071820.013
response to monosaccharideGO:003428430.013
protein secretionGO:000930610.013
intracellular signal transductionGO:0035556850.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
mitotic g2 dna damage checkpointGO:000709530.013
mitotic dna damage checkpointGO:004477340.012
system processGO:00030081850.012
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
nucleobase containing compound transportGO:001593120.012
neuron developmentGO:00486662620.012
negative regulation of intracellular protein transportGO:009031730.012
translational initiationGO:000641330.012
positive regulation of cell activationGO:005086710.012
rna 3 end processingGO:003112320.012
fatty acid catabolic processGO:000906210.012
response to nutrientGO:000758430.012
leukocyte proliferationGO:007066110.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
viral processGO:001603210.012
protein stabilizationGO:005082120.012
release of sequestered calcium ion into cytosolGO:005120930.012
regulation of rna biosynthetic processGO:20011412130.012
regulation of organ growthGO:004662030.012
rna modificationGO:000945120.012
negative regulation of protein localization to nucleusGO:190018120.012
peptide transportGO:001583310.012
embryonic organ developmentGO:00485683810.012
female meiotic divisionGO:000714320.012
regulation of neuronal synaptic plasticityGO:004816810.012
post embryonic organ developmentGO:004856940.012
membrane invaginationGO:001032410.012
tissue remodelingGO:004877140.012
cellular component biogenesisGO:00440851780.012
chemosensory behaviorGO:000763510.012
protein dephosphorylationGO:000647030.012
antimicrobial humoral responseGO:001973020.012
positive regulation of jnk cascadeGO:004633030.012
development of primary female sexual characteristicsGO:004654540.012
somatic muscle developmentGO:000752540.012
regulation of sodium ion transportGO:000202820.012
macroautophagyGO:001623610.012
regulation of peptidyl tyrosine phosphorylationGO:005073010.012
stem cell divisionGO:001714510.012
dna templated transcription elongationGO:000635430.012
signal transduction in absence of ligandGO:003803410.012
developmental programmed cell deathGO:001062340.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
cellular protein modification processGO:00064641000.012
regulation of protein complex disassemblyGO:004324410.012
neuron projection developmentGO:00311751800.012
positive regulation of chromatin modificationGO:190331010.012
cell deathGO:00082191210.012
establishment of rna localizationGO:005123630.011
b cell activationGO:004211320.011
actin polymerization or depolymerizationGO:000815420.011
phosphorus metabolic processGO:00067931090.011
centrosome duplicationGO:005129810.011
transcription from rna polymerase ii promoterGO:0006366800.011
positive regulation of translationGO:004572710.011
phagocytosis engulfmentGO:000691110.011
negative regulation of protein import into nucleusGO:004230820.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
alcohol biosynthetic processGO:004616520.011
double strand break repair via homologous recombinationGO:000072410.011
positive regulation of nitrogen compound metabolic processGO:0051173690.011
negative regulation of stem cell differentiationGO:200073720.011
phosphate containing compound metabolic processGO:00067961080.011
establishment of protein localization to plasma membraneGO:009000210.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
muscle cell differentiationGO:00426921390.011
oocyte anterior posterior axis specificationGO:000731440.011
mononuclear cell proliferationGO:003294310.011
camera type eye developmentGO:00430102220.011
axon developmentGO:00615641660.011
cytoskeleton dependent cytokinesisGO:006164030.011
negative regulation of metabolic processGO:0009892860.011
regulation of stem cell differentiationGO:200073640.011
lymphocyte proliferationGO:004665110.011
protein homooligomerizationGO:005126030.011
determination of bilateral symmetryGO:00098552040.011
positive regulation of leukocyte mediated immunityGO:000270510.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of dna replicationGO:000627530.011
protein complex disassemblyGO:004324110.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
regulation of exocytosisGO:001715710.011
cellular localizationGO:0051641970.011
regulation of epithelial cell proliferationGO:005067830.011
microtubule organizing center organizationGO:003102310.011
cellular response to radiationGO:007147840.011
macromolecule modificationGO:00434121110.011
negative regulation of macromolecule metabolic processGO:0010605760.011
positive regulation of multi organism processGO:004390230.011
peptidyl threonine phosphorylationGO:001810710.011
ovulation cycleGO:004269820.011
response to biotic stimulusGO:0009607970.011
regulation of transmembrane transporter activityGO:002289820.011
startle responseGO:000196440.011
negative regulation of multi organism processGO:004390130.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
regulation of cellular component organizationGO:0051128860.011
multicellular organismal metabolic processGO:004423620.010
regulation of microtubule cytoskeleton organizationGO:007050730.010
lipid homeostasisGO:005508830.010
centrosome cycleGO:000709810.010
regulation of ion transmembrane transporter activityGO:003241220.010
mrna 3 end processingGO:003112420.010
positive regulation of map kinase activityGO:004340630.010
apoptotic processGO:00069151160.010
dorsal ventral pattern formationGO:00099531250.010
neuron neuron synaptic transmissionGO:000727010.010
regulation of blood pressureGO:000821710.010
response to endogenous stimulusGO:0009719830.010
embryonic skeletal joint developmentGO:007249830.010
immune system developmentGO:00025201910.010
positive regulation of histone modificationGO:003105810.010
negative regulation of signalingGO:0023057960.010
protein modification processGO:00362111000.010
sensory organ morphogenesisGO:00905962000.010
regulation of carbohydrate metabolic processGO:000610940.010
carbohydrate homeostasisGO:003350010.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
post embryonic morphogenesisGO:000988640.010
positive regulation of cell divisionGO:005178120.010
regulation of inflammatory responseGO:005072720.010
recombinational repairGO:000072510.010
cytosolic calcium ion transportGO:006040130.010
response to hydrogen peroxideGO:004254230.010

ttc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.022
disease of metabolismDOID:001466700.018
musculoskeletal system diseaseDOID:1700.017
disease of cellular proliferationDOID:1456600.015
inherited metabolic disorderDOID:65500.014
organ system cancerDOID:005068600.014
cancerDOID:16200.014
muscular diseaseDOID:008000000.012
connective tissue diseaseDOID:6500.011
muscle tissue diseaseDOID:6600.010
myopathyDOID:42300.010