Danio rerio

0 known processes

pgpep1

pyroglutamyl-peptidase I

(Aliases: FLJ20208,MGC109902,im:6904079,zgc:109902)

pgpep1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.074
agingGO:000756820.049
establishment of protein localization to organelleGO:007259440.044
maintenance of locationGO:005123540.044
phagocytosisGO:000690930.044
endosomal transportGO:001619720.040
positive regulation of transportGO:005105020.038
nitrogen compound metabolic processGO:00068073190.037
guanosine containing compound metabolic processGO:190106840.035
cellular response to external stimulusGO:007149620.034
multicellular organism growthGO:003526440.033
guanosine containing compound catabolic processGO:190106920.033
cellular response to nutrient levelsGO:003166920.032
organelle fusionGO:004828430.032
golgi vesicle transportGO:004819330.032
protein localization to plasma membraneGO:007265910.031
cytokinesisGO:000091030.031
membrane fusionGO:006102520.031
gtp metabolic processGO:004603940.031
lipid storageGO:001991510.031
autophagyGO:000691440.031
meiotic nuclear divisionGO:000712640.030
cellular protein catabolic processGO:004425740.030
cellular response to extracellular stimulusGO:003166820.030
meiotic chromosome segregationGO:004513230.030
regulation of mrna splicing via spliceosomeGO:004802430.030
gtp catabolic processGO:000618420.030
mitochondrion organizationGO:000700540.030
regulation of protein transportGO:005122330.029
positive regulation of catabolic processGO:000989640.029
proteasomal protein catabolic processGO:001049820.029
proteolysis involved in cellular protein catabolic processGO:005160330.028
amine metabolic processGO:000930820.028
ubiquitin dependent protein catabolic processGO:000651130.028
regulation of protein complex assemblyGO:004325430.028
single organism membrane fusionGO:004480120.028
regulation of establishment of protein localizationGO:007020140.027
nucleocytoplasmic transportGO:000691340.027
regulation of protein catabolic processGO:004217610.027
modification dependent protein catabolic processGO:001994130.027
cellular amine metabolic processGO:004410620.026
cellular response to starvationGO:000926710.026
cellular macromolecule metabolic processGO:00442603910.026
positive regulation of cell cycleGO:004578730.026
modification dependent macromolecule catabolic processGO:004363230.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
response to drugGO:004249330.026
positive regulation of cellular component biogenesisGO:004408930.026
regulation of multicellular organism growthGO:004001440.026
positive regulation of cellular catabolic processGO:003133130.025
regulation of synaptic plasticityGO:004816710.025
regulation of cytokine productionGO:000181730.025
meiotic cell cycle processGO:190304630.025
single organism nuclear importGO:190259330.024
central nervous system developmentGO:00074173870.024
stem cell maintenanceGO:001982740.024
protein importGO:001703830.024
transportGO:00068102200.023
heterocycle metabolic processGO:00464832900.023
regulation of bindingGO:005109830.023
regulation of cell shapeGO:000836010.023
positive regulation of secretionGO:005104710.023
establishment of localizationGO:00512342440.023
organonitrogen compound metabolic processGO:1901564740.023
macroautophagyGO:001623610.023
nuclear importGO:005117030.022
regulation of reactive oxygen species metabolic processGO:200037720.022
regulation of protein targetingGO:190353320.022
cellular nitrogen compound biosynthetic processGO:00442712180.022
response to stressGO:00069502630.022
rna localizationGO:000640340.021
spermatid developmentGO:000728620.021
spermatid differentiationGO:004851520.021
nucleobase containing compound metabolic processGO:00061392740.021
regulation of cellular amine metabolic processGO:003323800.021
vasculature developmentGO:00019442780.021
signal transductionGO:00071654550.021
centrosome organizationGO:005129710.021
protein import into nucleusGO:000660630.021
regulation of mrna processingGO:005068430.021
regulation of cytoplasmic transportGO:190364940.021
biosynthetic processGO:00090582940.021
nuclear transportGO:005116940.021
brain developmentGO:00074202930.021
single organism localizationGO:19025782250.021
organic cyclic compound metabolic processGO:19013603010.021
cellular nitrogen compound metabolic processGO:00346412900.020
cellular biosynthetic processGO:00442492860.020
negative regulation of protein phosphorylationGO:000193340.020
cellular component morphogenesisGO:00329893360.020
protein acetylationGO:000647320.020
cell cycle g1 s phase transitionGO:004484310.020
positive regulation of secretion by cellGO:190353210.020
negative regulation of biological processGO:00485193040.020
rna metabolic processGO:00160702190.020
cellular component movementGO:00069283350.020
response to chemicalGO:00422213200.020
regulation of intracellular protein transportGO:003315730.020
regulation of protein localization to nucleusGO:190018020.020
immune system processGO:00023762410.020
regulation of synapse assemblyGO:005196330.020
tube morphogenesisGO:00352393490.020
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.019
translational initiationGO:000641330.019
regulation of cellular amino acid metabolic processGO:000652100.019
regulation of metal ion transportGO:001095940.019
regulation of alternative mrna splicing via spliceosomeGO:000038110.019
positive regulation of protein complex assemblyGO:003133420.019
regulation of protein import into nucleusGO:004230620.019
protein targeting to nucleusGO:004474430.019
production of molecular mediator of immune responseGO:000244020.019
g1 s transition of mitotic cell cycleGO:000008210.019
single organism transportGO:00447652060.019
cellular component disassemblyGO:002241110.019
regulation of nucleotide catabolic processGO:003081120.019
response to uvGO:000941130.019
regulation of meiotic cell cycleGO:005144510.018
cell projection organizationGO:00300302840.018
cellular amino acid metabolic processGO:000652070.018
regulation of biological qualityGO:00650082630.018
morphogenesis of an epitheliumGO:00020093330.018
cell part morphogenesisGO:00329902460.018
regulation of neural precursor cell proliferationGO:200017730.018
peptidyl lysine acetylationGO:001839420.018
locomotionGO:00400113130.018
single organism organelle organizationGO:19025891990.018
regulation of cell activationGO:005086510.018
protein secretionGO:000930610.018
regulation of macromolecule metabolic processGO:00602553170.018
single organism metabolic processGO:00447102170.018
membrane invaginationGO:001032410.018
sensory organ developmentGO:00074233930.018
protein polymerizationGO:005125840.018
synaptic vesicle localizationGO:009747910.018
stem cell proliferationGO:007208940.018
cell migrationGO:00164772370.018
organelle organizationGO:00069962270.018
head developmentGO:00603223030.017
regulation of synapse organizationGO:005080730.017
cytoskeleton dependent cytokinesisGO:006164030.017
internal protein amino acid acetylationGO:000647520.017
actin polymerization or depolymerizationGO:000815420.017
alternative mrna splicing via spliceosomeGO:000038010.017
rna biosynthetic processGO:00327741810.017
protein acylationGO:004354330.017
gene expressionGO:00104672520.017
cellular carbohydrate metabolic processGO:004426240.017
negative regulation of protein complex assemblyGO:003133310.017
regulation of multicellular organismal processGO:00512392770.017
regulation of nucleoside metabolic processGO:000911820.017
generation of neuronsGO:00486993850.017
regulation of purine nucleotide catabolic processGO:003312120.017
protein complex disassemblyGO:004324110.017
exocytosisGO:000688710.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
internal peptidyl lysine acetylationGO:001839320.016
response to external stimulusGO:00096052640.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
regulation of primary metabolic processGO:00800903110.016
neuron differentiationGO:00301823530.016
cognitionGO:005089010.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
nucleic acid metabolic processGO:00903042440.016
macromolecular complex disassemblyGO:003298410.016
embryonic organ developmentGO:00485683810.016
regulation of cellular biosynthetic processGO:00313262450.016
regulation of production of molecular mediator of immune responseGO:000270010.016
nucleic acid templated transcriptionGO:00976591810.016
i kappab kinase nf kappab signalingGO:000724940.016
cellular aromatic compound metabolic processGO:00067252950.016
vacuolar transportGO:000703420.016
actin filament polymerizationGO:003004120.016
regulation of response to biotic stimulusGO:000283120.016
oxoacid metabolic processGO:0043436310.016
regulation of cellular ketone metabolic processGO:001056570.016
regulation of developmental processGO:00507932470.016
positive regulation of cytoskeleton organizationGO:005149530.016
cytosolic calcium ion transportGO:006040130.015
organic acid metabolic processGO:0006082310.015
synaptic growth at neuromuscular junctionGO:005112420.015
cell morphogenesisGO:00009022890.015
development of primary female sexual characteristicsGO:004654540.015
macromolecule biosynthetic processGO:00090592270.015
female sex differentiationGO:004666040.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015
extrinsic apoptotic signaling pathwayGO:009719130.015
regulation of metabolic processGO:00192223590.015
protein localization to nucleusGO:003450430.015
protein metabolic processGO:00195381830.015
nuclear exportGO:005116810.015
positive regulation of cell activationGO:005086710.015
regulation of gtpase activityGO:004308720.015
regulation of nucleocytoplasmic transportGO:004682220.015
cellular component biogenesisGO:00440851780.015
peptidyl serine modificationGO:001820920.015
digestive tract morphogenesisGO:00485462310.015
post golgi vesicle mediated transportGO:000689210.015
blood vessel developmentGO:00015682460.015
cellular response to topologically incorrect proteinGO:003596720.015
cell substrate adhesionGO:003158940.015
cell cycle g2 m phase transitionGO:004483940.015
stem cell divisionGO:001714510.015
small molecule metabolic processGO:0044281770.015
regulation of biosynthetic processGO:00098892500.015
gastrulationGO:00073692080.015
interspecies interaction between organismsGO:004441940.015
negative regulation of catabolic processGO:000989530.015
cellular ketone metabolic processGO:0042180110.015
positive regulation of dna metabolic processGO:005105410.015
female meiotic divisionGO:000714320.014
positive regulation of cellular amine metabolic processGO:003324000.014
cell motilityGO:00488702440.014
regulation of sequestering of calcium ionGO:005128240.014
locomotor rhythmGO:004547530.014
regulation of protein ubiquitinationGO:003139630.014
synaptic vesicle transportGO:004848910.014
lateral inhibitionGO:004633110.014
phagocytosis engulfmentGO:000691110.014
protein dephosphorylationGO:000647030.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
peptidyl serine phosphorylationGO:001810510.014
antimicrobial humoral responseGO:001973020.014
peptide transportGO:001583310.014
cellular response to biotic stimulusGO:007121630.014
regulation of gtp catabolic processGO:003312420.014
determination of bilateral symmetryGO:00098552040.014
regulation of transcription dna templatedGO:00063552130.014
regulation of cellular protein catabolic processGO:190336210.014
transcription dna templatedGO:00063511810.014
sequestering of calcium ionGO:005120830.014
cell matrix adhesionGO:000716040.014
regulation of gene expressionGO:00104682650.014
localization of cellGO:00516742440.014
microtubule organizing center organizationGO:003102310.014
determination of left right symmetryGO:00073681790.014
compound eye developmentGO:004874920.014
nucleobase containing compound biosynthetic processGO:00346542050.014
gland developmentGO:00487321430.014
immune system developmentGO:00025201910.014
regulation of peptidyl tyrosine phosphorylationGO:005073010.014
female gonad developmentGO:000858540.014
cellular amide metabolic processGO:004360340.014
regulation of organelle assemblyGO:190211540.014
regulation of stem cell proliferationGO:007209120.014
ear developmentGO:00435831270.014
embryonic organ morphogenesisGO:00485622740.014
aromatic compound biosynthetic processGO:00194382170.014
carboxylic acid metabolic processGO:0019752220.014
liver developmentGO:0001889960.014
cellular localizationGO:0051641970.013
positive regulation of immune effector processGO:000269930.013
negative regulation of kinase activityGO:003367340.013
positive regulation of nucleotide catabolic processGO:003081310.013
cellular response to radiationGO:007147840.013
positive regulation of nucleoside metabolic processGO:004597910.013
regulation of cell communicationGO:00106462320.013
positive regulation of translationGO:004572710.013
blood vessel morphogenesisGO:00485142160.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
negative regulation of cellular processGO:00485232830.013
response to unfolded proteinGO:000698620.013
regulation of protein modification by small protein conjugation or removalGO:190332030.013
positive regulation of cell adhesionGO:004578510.013
positive regulation of gtp catabolic processGO:003312610.013
negative regulation of protein kinase activityGO:000646940.013
mitotic dna integrity checkpointGO:004477440.013
protein polyubiquitinationGO:000020940.013
leukocyte proliferationGO:007066110.013
double strand break repairGO:000630230.013
positive regulation of stress activated mapk cascadeGO:003287430.013
nucleic acid transportGO:005065720.013
negative regulation of cellular catabolic processGO:003133030.013
regulation of cellular metabolic processGO:00313233200.013
regulation of rna metabolic processGO:00512522240.013
neuroblast proliferationGO:000740520.013
regulation of nitrogen compound metabolic processGO:00511712510.013
regulation of nucleobase containing compound metabolic processGO:00192192500.013
chemosensory behaviorGO:000763510.013
organic cyclic compound biosynthetic processGO:19013622230.013
negative regulation of intracellular transportGO:003238730.013
regulation of jak stat cascadeGO:004642530.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
heterocycle biosynthetic processGO:00181302150.013
system processGO:00030081850.013
digestive system developmentGO:00551232890.013
regulation of reproductive processGO:200024140.013
hepaticobiliary system developmentGO:0061008980.013
response to topologically incorrect proteinGO:003596620.013
cell projection morphogenesisGO:00488582440.013
regulation of macromolecule biosynthetic processGO:00105562250.013
spindle assemblyGO:005122520.012
regionalizationGO:00030022740.012
neuron developmentGO:00486662620.012
tissue remodelingGO:004877140.012
establishment of synaptic vesicle localizationGO:009748010.012
cell surface receptor signaling pathwayGO:00071663250.012
negative regulation of protein localization to nucleusGO:190018120.012
regulation of autophagyGO:001050630.012
heart developmentGO:00075073130.012
response to carbohydrateGO:000974330.012
neurotransmitter secretionGO:000726920.012
digestive tract developmentGO:00485652650.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
activation of mapk activityGO:000018730.012
establishment of localization in cellGO:0051649770.012
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.012
b cell activationGO:004211320.012
sequestering of metal ionGO:005123830.012
negative regulation of cytoplasmic transportGO:190365020.012
organic substance biosynthetic processGO:19015762890.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.012
regulation of anatomical structure morphogenesisGO:00226031300.012
regulation of neurotransmitter secretionGO:004692810.012
positive regulation of cytokine productionGO:000181920.012
specification of symmetryGO:00097992040.012
small molecule catabolic processGO:004428230.012
inner ear developmentGO:00488391260.012
cellular response to molecule of bacterial originGO:007121930.012
regulation of multicellular organismal developmentGO:20000262230.012
ribonucleoside monophosphate catabolic processGO:000915840.012
cellular response to chemical stimulusGO:00708871570.012
dna templated transcription elongationGO:000635430.012
calcium ion transport into cytosolGO:006040230.012
cell substrate junction assemblyGO:000704420.012
neurotransmitter transportGO:000683620.012
cell deathGO:00082191210.011
regulation of cell substrate adhesionGO:001081010.011
response to alkaloidGO:004327920.011
atp catabolic processGO:000620040.011
cellular macromolecule biosynthetic processGO:00346452240.011
primary neural tube formationGO:001402010.011
positive regulation of gtpase activityGO:004354710.011
regulation of transporter activityGO:003240920.011
regulation of cellular macromolecule biosynthetic processGO:20001122220.011
regulation of protein complex disassemblyGO:004324410.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
positive regulation of map kinase activityGO:004340630.011
nucleobase containing compound transportGO:001593120.011
germ line stem cell maintenanceGO:003071820.011
negative regulation of cytokine productionGO:000181810.011
regulation of erk1 and erk2 cascadeGO:007037240.011
regulation of cell projection assemblyGO:006049140.011
pigment granule localizationGO:0051875250.011
er to golgi vesicle mediated transportGO:000688810.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
positive regulation of biological processGO:00485182530.011
release of sequestered calcium ion into cytosolGO:005120930.011
mononuclear cell proliferationGO:003294310.011
mitotic cell cycle embryonicGO:004544820.011
establishment of rna localizationGO:005123630.011
regulation of exocytosisGO:001715710.011
cellular component assemblyGO:00226071700.011
g2 m transition of mitotic cell cycleGO:000008640.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.011
viral processGO:001603210.011
apoptotic processGO:00069151160.011
regulation of signalingGO:00230512350.011
lymphocyte proliferationGO:004665110.011
carbohydrate homeostasisGO:003350010.011
cellular protein metabolic processGO:00442671290.011
angiogenesisGO:00015251580.011
phosphate containing compound metabolic processGO:00067961080.011
positive regulation of cellular processGO:00485222010.011
regulation of hormone secretionGO:004688320.011
synaptic vesicle recyclingGO:003646510.011
deathGO:00162651210.011
protein targeting to membraneGO:000661210.011
response to nutrientGO:000758430.011
regulation of nucleic acid templated transcriptionGO:19035062130.011
sensory organ morphogenesisGO:00905962000.011
single fertilizationGO:000733830.010
negative regulation of immune responseGO:005077720.010
meiosis iGO:000712710.010
g2 dna damage checkpointGO:003157230.010
adult behaviorGO:003053420.010
hormone secretionGO:004687920.010
centrosome cycleGO:000709810.010
negative regulation of multi organism processGO:004390130.010
mitotic cytokinesisGO:000028130.010
response to monosaccharideGO:003428430.010
rna export from nucleusGO:000640510.010
golgi organizationGO:000703010.010
axon developmentGO:00615641660.010
positive regulation of leukocyte differentiationGO:190210710.010
positive regulation of multi organism processGO:004390230.010
transmission of nerve impulseGO:0019226190.010
transcription elongation from rna polymerase ii promoterGO:000636830.010
eye developmentGO:00016542770.010
lamellipodium organizationGO:009758110.010
negative regulation of protein serine threonine kinase activityGO:007190120.010
regulation of response to stimulusGO:00485832690.010
homeostatic processGO:00425921420.010
peptide metabolic processGO:000651810.010
positive regulation of jun kinase activityGO:004350720.010
cellular response to lipopolysaccharideGO:007122230.010
cellular response to unfolded proteinGO:003462020.010

pgpep1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
nervous system diseaseDOID:86300.025
musculoskeletal system diseaseDOID:1700.018
cardiovascular system diseaseDOID:128700.017
disease of metabolismDOID:001466700.014
muscle tissue diseaseDOID:6600.013
muscular diseaseDOID:008000000.013
myopathyDOID:42300.013
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
organ system cancerDOID:005068600.012
heart diseaseDOID:11400.011
cardiomyopathyDOID:005070000.011
intrinsic cardiomyopathyDOID:006003600.011
inherited metabolic disorderDOID:65500.011