Danio rerio

10 known processes

cx45.6

connexin 45.6

(Aliases: zgc:195347,zgc:195362)

cx45.6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217620.528
embryonic organ developmentGO:00485683810.528
embryonic organ morphogenesisGO:00485622740.344
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.304
regulation of multicellular organismal processGO:00512392770.290
multicellular organismal signalingGO:0035637220.223
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.211
transmembrane transportGO:00550851200.166
neuron neuron synaptic transmissionGO:000727010.153
sensory organ morphogenesisGO:00905962000.137
regulation of nitrogen compound metabolic processGO:00511712510.134
cation transmembrane transportGO:0098655650.122
cellular biosynthetic processGO:00442492860.112
oxidative demethylationGO:007098910.109
immune system processGO:00023762410.107
specification of symmetryGO:00097992040.096
digestive tract developmentGO:00485652650.096
regulation of response to oxidative stressGO:190288220.093
sensory organ developmentGO:00074233930.092
cell death in response to oxidative stressGO:003647320.092
cellular respirationGO:004533330.089
regulation of cellular response to oxidative stressGO:190040720.086
neuron differentiationGO:00301823530.080
organic anion transportGO:0015711150.077
erythrocyte differentiationGO:0030218540.075
determination of heart left right asymmetryGO:00613711170.074
system processGO:00030081850.073
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.072
nitrogen compound metabolic processGO:00068073190.072
erythrocyte homeostasisGO:0034101550.072
cellular aromatic compound metabolic processGO:00067252950.071
organic substance biosynthetic processGO:19015762890.069
angiogenesisGO:00015251580.068
response to arsenic containing substanceGO:004668550.067
regulation of membrane repolarizationGO:006030610.067
actin filament based movementGO:003004810.065
circulatory system processGO:0003013870.065
regulation of nucleobase containing compound metabolic processGO:00192192500.064
nucleic acid metabolic processGO:00903042440.064
regulation of biological qualityGO:00650082630.062
regulation of primary metabolic processGO:00800903110.062
regulation of cellular biosynthetic processGO:00313262450.061
cardiac conductionGO:006133730.058
regulation of oxidative stress induced cell deathGO:190320120.058
nucleobase containing compound biosynthetic processGO:00346542050.057
heterocycle metabolic processGO:00464832900.055
regulation of membrane potentialGO:0042391230.053
determination of left right symmetryGO:00073681790.053
synaptic transmission glycinergicGO:006001210.052
muscle hypertrophyGO:001489620.051
regulation of inhibitory postsynaptic membrane potentialGO:006008010.048
regulation of stem cell proliferationGO:007209120.047
organic cyclic compound biosynthetic processGO:19013622230.046
regulation of transcription dna templatedGO:00063552130.046
blood vessel developmentGO:00015682460.045
regulation of muscle contractionGO:000693730.045
tube morphogenesisGO:00352393490.044
sarcomerogenesisGO:004876940.043
multicellular organism growthGO:003526440.042
digestive system developmentGO:00551232890.042
ion transmembrane transportGO:0034220910.040
heart loopingGO:0001947940.040
determination of bilateral symmetryGO:00098552040.040
membrane repolarizationGO:008600920.039
action potentialGO:0001508190.039
single organism localizationGO:19025782250.038
negative regulation of dna metabolic processGO:005105340.038
monovalent inorganic cation transportGO:0015672420.037
transcription from rna polymerase ii promoterGO:0006366800.035
myeloid cell differentiationGO:0030099860.034
centrosome organizationGO:005129710.034
cardiac muscle tissue developmentGO:0048738480.034
positive regulation of biological processGO:00485182530.033
anion transportGO:0006820380.033
organic cyclic compound metabolic processGO:19013603010.032
inorganic cation transmembrane transportGO:0098662500.032
myeloid cell homeostasisGO:0002262560.031
inner ear developmentGO:00488391260.031
cellular nitrogen compound metabolic processGO:00346412900.029
heterocycle biosynthetic processGO:00181302150.029
heart contractionGO:0060047710.029
macromolecule biosynthetic processGO:00090592270.028
regulation of cellular macromolecule biosynthetic processGO:20001122220.028
posterior lateral line developmentGO:0048916380.027
biosynthetic processGO:00090582940.027
inorganic ion transmembrane transportGO:0098660570.027
heart morphogenesisGO:00030071560.027
sodium ion transmembrane transportGO:0035725210.027
cellular macromolecule biosynthetic processGO:00346452240.026
cellular nitrogen compound biosynthetic processGO:00442712180.026
locomotionGO:00400113130.026
hematopoietic or lymphoid organ developmentGO:00485341910.026
eye developmentGO:00016542770.026
vasculature developmentGO:00019442780.025
heart developmentGO:00075073130.025
neuron developmentGO:00486662620.025
embryonic hemopoiesisGO:0035162530.025
negative regulation of cellular processGO:00485232830.025
blood vessel morphogenesisGO:00485142160.024
small molecule catabolic processGO:004428230.024
regulation of mesenchymal cell proliferationGO:001046410.023
cell projection organizationGO:00300302840.023
striated muscle tissue developmentGO:00147061100.023
glomerulus vasculature developmentGO:007201220.023
regulation of cell communicationGO:00106462320.023
amino acid transportGO:000686520.023
kidney vasculature developmentGO:006144020.022
morphogenesis of an epitheliumGO:00020093330.022
cellular macromolecule metabolic processGO:00442603910.022
rna biosynthetic processGO:00327741810.022
cell part morphogenesisGO:00329902460.021
nucleobase containing compound metabolic processGO:00061392740.021
cell cell signalingGO:0007267520.021
generation of neuronsGO:00486993850.021
glial cell proliferationGO:001400940.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
cation transportGO:0006812810.020
regulation of cellular metabolic processGO:00313233200.020
artery developmentGO:0060840220.020
eye morphogenesisGO:00485921440.020
negative regulation of dna recombinationGO:004591020.020
regulation of signalingGO:00230512350.020
response to chemicalGO:00422213200.020
synaptic growth at neuromuscular junctionGO:005112420.019
heart processGO:0003015710.019
regulation of protein ubiquitinationGO:003139630.019
single organism metabolic processGO:00447102170.019
adult behaviorGO:003053420.019
negative regulation of intrinsic apoptotic signaling pathwayGO:200124380.019
stem cell proliferationGO:007208940.018
ear developmentGO:00435831270.018
inner ear morphogenesisGO:0042472630.018
cardiac muscle cell developmentGO:0055013200.018
homeostasis of number of cellsGO:0048872620.018
stem cell divisionGO:001714510.018
meiotic nuclear divisionGO:000712640.018
regulation of metal ion transportGO:001095940.018
regulation of blood vessel sizeGO:005088020.018
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.018
negative regulation of biological processGO:00485193040.018
regulation of multicellular organism growthGO:004001440.018
cardiac atrium morphogenesisGO:000320920.018
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
monoamine transportGO:001584410.017
left right pattern formationGO:0060972190.017
regulation of cell deathGO:00109411030.017
transcription dna templatedGO:00063511810.016
response to immobilization stressGO:003590210.016
regulation of bindingGO:005109830.016
regulation of nucleoside metabolic processGO:000911820.016
negative regulation of oxidative stress induced cell deathGO:190320220.016
negative regulation of response to stimulusGO:00485851040.016
signal transductionGO:00071654550.016
mitochondrion organizationGO:000700540.015
regulation of blood pressureGO:000821710.015
ion transportGO:00068111140.015
somatic muscle developmentGO:000752540.015
cellular component morphogenesisGO:00329893360.015
regulation of macromolecule metabolic processGO:00602553170.015
hemopoiesisGO:00300971830.014
positive regulation of mesenchymal cell proliferationGO:000205310.014
cellular response to oxygen levelsGO:007145310.014
larval developmentGO:000216420.014
regulation of response to stimulusGO:00485832690.014
regulation of cardiac muscle contractionGO:005511720.014
mitochondrial atp synthesis coupled electron transportGO:004277510.014
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.013
regulation of rna biosynthetic processGO:20011412130.013
water homeostasisGO:003010440.013
ear morphogenesisGO:0042471640.013
mitotic recombinationGO:000631220.013
negative regulation of macromolecule metabolic processGO:0010605760.013
fin developmentGO:0033333770.013
muscle system processGO:0003012200.013
cell projection assemblyGO:0030031640.013
endosomal transportGO:001619720.013
regulation of biosynthetic processGO:00098892500.013
regulation of system processGO:0044057400.013
response to hydrogen peroxideGO:004254230.013
embryonic heart tube morphogenesisGO:00031431080.012
posterior lateral line neuromast primordium migrationGO:0048920120.012
lipid storageGO:001991510.012
nucleotide metabolic processGO:0009117280.012
regulation of dendrite developmentGO:005077330.012
homeostatic processGO:00425921420.012
positive regulation of catabolic processGO:000989640.012
regulation of apoptotic processGO:0042981980.012
apoptotic processGO:00069151160.012
gene expressionGO:00104672520.012
positive regulation of cellular catabolic processGO:003133130.012
cellular component movementGO:00069283350.012
neurotransmitter transportGO:000683620.012
metal ion homeostasisGO:0055065260.012
regulation of metabolic processGO:00192223590.012
rna metabolic processGO:00160702190.012
phosphate containing compound metabolic processGO:00067961080.011
neurotransmitter secretionGO:000726920.011
cardiac myofibril assemblyGO:005500390.011
response to stressGO:00069502630.011
gastrulationGO:00073692080.011
regulation of purine nucleotide catabolic processGO:003312120.011
regulation of tube sizeGO:003515020.011
gland developmentGO:00487321430.011
synaptic vesicle localizationGO:009747910.011
myelination in peripheral nervous systemGO:002201140.011
regulation of transmembrane transporter activityGO:002289820.011
actin mediated cell contractionGO:007025210.011
regulation of nucleotide catabolic processGO:003081120.011
negative regulation of protein kinase activityGO:000646940.011
organelle assemblyGO:00709251100.011
regulation of rna metabolic processGO:00512522240.011
response to abiotic stimulusGO:00096281220.011
neurological system processGO:0050877620.010
positive regulation of transportGO:005105020.010
cardiac muscle cell contractionGO:008600310.010
regulation of jak stat cascadeGO:004642530.010
cardiac cell developmentGO:0055006210.010
positive regulation of jak stat cascadeGO:004642720.010
synaptic transmission cholinergicGO:000727140.010
camera type eye developmentGO:00430102220.010

cx45.6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
cardiovascular system diseaseDOID:128700.015
cardiomyopathyDOID:005070000.015
musculoskeletal system diseaseDOID:1700.015
muscular diseaseDOID:008000000.015
intrinsic cardiomyopathyDOID:006003600.015
heart diseaseDOID:11400.015
muscle tissue diseaseDOID:6600.015
myopathyDOID:42300.015