Danio rerio

0 known processes

zgc:103506

zgc:103506

(Aliases: spire2)

zgc:103506 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.063
agingGO:000756820.059
cellular macromolecule metabolic processGO:00442603910.054
heterocycle metabolic processGO:00464832900.046
stem cell maintenanceGO:001982740.044
nitrogen compound metabolic processGO:00068073190.043
organic cyclic compound metabolic processGO:19013603010.042
cellular nitrogen compound metabolic processGO:00346412900.042
multicellular organism growthGO:003526440.039
regulation of cellular amine metabolic processGO:003323800.038
amine metabolic processGO:000930820.038
cellular amine metabolic processGO:004410620.036
regulation of metabolic processGO:00192223590.036
cognitionGO:005089010.035
regulation of macromolecule metabolic processGO:00602553170.035
positive regulation of cell cycleGO:004578730.035
rna metabolic processGO:00160702190.034
regulation of primary metabolic processGO:00800903110.034
signal transductionGO:00071654550.033
gene expressionGO:00104672520.033
eye developmentGO:00016542770.033
cellular biosynthetic processGO:00442492860.033
cellular aromatic compound metabolic processGO:00067252950.032
positive regulation of cellular catabolic processGO:003133130.032
cytokinesisGO:000091030.032
regulation of cellular ketone metabolic processGO:001056570.031
positive regulation of catabolic processGO:000989640.031
regulation of nitrogen compound metabolic processGO:00511712510.031
generation of neuronsGO:00486993850.030
heterocycle biosynthetic processGO:00181302150.030
regulation of cellular amino acid metabolic processGO:000652100.030
proteolysis involved in cellular protein catabolic processGO:005160330.030
single organism metabolic processGO:00447102170.030
maintenance of locationGO:005123540.030
nucleic acid templated transcriptionGO:00976591810.030
regulation of cellular metabolic processGO:00313233200.029
regulation of multicellular organism growthGO:004001440.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
immune system processGO:00023762410.029
nucleic acid metabolic processGO:00903042440.029
nucleobase containing compound metabolic processGO:00061392740.029
cellular protein catabolic processGO:004425740.028
cellular component movementGO:00069283350.028
ubiquitin dependent protein catabolic processGO:000651130.028
biosynthetic processGO:00090582940.028
positive regulation of transportGO:005105020.028
modification dependent protein catabolic processGO:001994130.027
meiotic nuclear divisionGO:000712640.027
phagocytosisGO:000690930.027
establishment of protein localization to organelleGO:007259440.026
modification dependent macromolecule catabolic processGO:004363230.026
regulation of establishment of protein localizationGO:007020140.026
organic substance biosynthetic processGO:19015762890.026
organonitrogen compound metabolic processGO:1901564740.026
cellular ketone metabolic processGO:0042180110.026
synaptic growth at neuromuscular junctionGO:005112420.026
ribonucleoside monophosphate catabolic processGO:000915840.025
mitochondrion organizationGO:000700540.025
cell surface receptor signaling pathwayGO:00071663250.025
negative regulation of protein phosphorylationGO:000193340.025
cellular amino acid metabolic processGO:000652070.025
guanosine containing compound metabolic processGO:190106840.024
guanosine containing compound catabolic processGO:190106920.024
purine ribonucleoside monophosphate catabolic processGO:000916940.024
oxoacid metabolic processGO:0043436310.024
gtp catabolic processGO:000618420.024
cell migrationGO:00164772370.024
negative regulation of protein kinase activityGO:000646940.024
positive regulation of cellular amine metabolic processGO:003324000.024
gtp metabolic processGO:004603940.024
macromolecule biosynthetic processGO:00090592270.024
nuclear transportGO:005116940.024
response to chemicalGO:00422213200.024
regulation of protein catabolic processGO:004217610.024
regulation of gene expressionGO:00104682650.023
transcription dna templatedGO:00063511810.023
aromatic compound biosynthetic processGO:00194382170.023
proteasomal protein catabolic processGO:001049820.023
nucleobase containing compound biosynthetic processGO:00346542050.023
regulation of reproductive processGO:200024140.023
regulation of biosynthetic processGO:00098892500.023
protein heterooligomerizationGO:005129110.023
organic acid metabolic processGO:0006082310.023
immune system developmentGO:00025201910.023
small molecule metabolic processGO:0044281770.023
regulation of bindingGO:005109830.023
regulation of meiotic cell cycleGO:005144510.022
organic cyclic compound biosynthetic processGO:19013622230.022
positive regulation of cellular component biogenesisGO:004408930.022
protein acetylationGO:000647320.022
regulation of macromolecule biosynthetic processGO:00105562250.022
neuron developmentGO:00486662620.022
regulation of metal ion transportGO:001095940.022
carboxylic acid metabolic processGO:0019752220.022
stem cell proliferationGO:007208940.022
negative regulation of cellular processGO:00485232830.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
regulation of cytokine productionGO:000181730.021
nucleocytoplasmic transportGO:000691340.021
regulation of cellular macromolecule biosynthetic processGO:20001122220.021
regulation of cellular biosynthetic processGO:00313262450.021
cellular component morphogenesisGO:00329893360.021
protein localization to nucleusGO:003450430.021
rna biosynthetic processGO:00327741810.021
regulation of nucleobase containing compound metabolic processGO:00192192500.021
tube morphogenesisGO:00352393490.021
cell motilityGO:00488702440.021
organelle organizationGO:00069962270.021
Human
localization of cellGO:00516742440.021
autophagyGO:000691440.021
regulation of protein complex assemblyGO:004325430.021
neuron differentiationGO:00301823530.021
regulation of cytoplasmic transportGO:190364940.021
cytoskeleton dependent cytokinesisGO:006164030.021
cellular macromolecule biosynthetic processGO:00346452240.020
embryonic organ developmentGO:00485683810.020
establishment of localizationGO:00512342440.020
Human
transportGO:00068102200.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
peptidyl lysine acetylationGO:001839420.020
response to stressGO:00069502630.020
cellular response to external stimulusGO:007149620.020
protein metabolic processGO:00195381830.020
spermatid differentiationGO:004851520.020
exocytosisGO:000688710.020
lipid catabolic processGO:001604240.020
cellular response to extracellular stimulusGO:003166820.020
regulation of biological qualityGO:00650082630.020
response to external stimulusGO:00096052640.020
internal protein amino acid acetylationGO:000647520.020
chemosensory behaviorGO:000763510.020
sensory organ developmentGO:00074233930.020
adult behaviorGO:003053420.020
neurotransmitter secretionGO:000726920.020
negative regulation of kinase activityGO:003367340.020
single organism localizationGO:19025782250.019
Human
digestive system developmentGO:00551232890.019
regulation of signalingGO:00230512350.019
compound eye developmentGO:004874920.019
protein importGO:001703830.019
regulation of synapse organizationGO:005080730.019
meiotic cell cycle processGO:190304630.019
Human
cell projection organizationGO:00300302840.019
lipid storageGO:001991510.019
regulation of cell activationGO:005086510.019
regulation of rna biosynthetic processGO:20011412130.019
locomotionGO:00400113130.019
cell part morphogenesisGO:00329902460.019
internal peptidyl lysine acetylationGO:001839320.018
protein acylationGO:004354330.018
atp catabolic processGO:000620040.018
morphogenesis of an epitheliumGO:00020093330.018
camera type eye developmentGO:00430102220.018
regulation of signal transductionGO:00099662250.018
negative regulation of biological processGO:00485193040.018
neurotransmitter transportGO:000683620.018
neuron neuron synaptic transmissionGO:000727010.018
hemopoiesisGO:00300971830.018
cellular amide metabolic processGO:004360340.018
nuclear importGO:005117030.018
protein localization to plasma membraneGO:007265910.018
regulation of peptidyl tyrosine phosphorylationGO:005073010.018
regulation of synaptic growth at neuromuscular junctionGO:000858210.018
cell projection morphogenesisGO:00488582440.018
purine nucleoside monophosphate catabolic processGO:000912840.017
regulation of rna metabolic processGO:00512522240.017
regulation of protein ubiquitinationGO:003139630.017
regulation of mrna splicing via spliceosomeGO:004802430.017
golgi vesicle transportGO:004819330.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
cellular component assemblyGO:00226071700.017
extrinsic apoptotic signaling pathwayGO:009719130.017
transcription from rna polymerase ii promoterGO:0006366800.017
regulation of protein transportGO:005122330.017
cell morphogenesisGO:00009022890.017
response to carbohydrateGO:000974330.017
homeostatic processGO:00425921420.017
response to drugGO:004249330.016
regulation of cell shapeGO:000836010.016
single fertilizationGO:000733830.016
response to monosaccharideGO:003428430.016
cellular response to lipopolysaccharideGO:007122230.016
regulation of nucleoside metabolic processGO:000911820.016
central nervous system developmentGO:00074173870.016
positive regulation of biological processGO:00485182530.016
erk1 and erk2 cascadeGO:007037140.016
leukocyte proliferationGO:007066110.016
positive regulation of cytosolic calcium ion concentrationGO:000720440.016
regulation of stem cell proliferationGO:007209120.016
regulation of purine nucleotide catabolic processGO:003312120.016
hematopoietic or lymphoid organ developmentGO:00485341910.016
regulation of nucleotide catabolic processGO:003081120.016
cellular carbohydrate metabolic processGO:004426240.016
regulation of transcription dna templatedGO:00063552130.016
regulation of synapse assemblyGO:005196330.016
locomotor rhythmGO:004547530.016
regulation of mrna processingGO:005068430.016
female sex differentiationGO:004666040.016
cellular response to nutrient levelsGO:003166920.016
response to hexoseGO:000974630.016
single organism transportGO:00447652060.016
regulation of neural precursor cell proliferationGO:200017730.016
regulation of erk1 and erk2 cascadeGO:007037240.016
regulation of dna replicationGO:000627530.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
antimicrobial humoral responseGO:001973020.015
negative regulation of nuclear divisionGO:005178430.015
protein import into nucleusGO:000660630.015
mitotic cell cycle embryonicGO:004544820.015
rna localizationGO:000640340.015
negative regulation of catabolic processGO:000989530.015
single organism nuclear importGO:190259330.015
cellular protein metabolic processGO:00442671290.015
protein targeting to nucleusGO:004474430.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
vasculature developmentGO:00019442780.015
adherens junction organizationGO:003433240.015
fertilizationGO:000956630.015
muscle structure developmentGO:00610611960.015
centrosome cycleGO:000709810.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of synaptic plasticityGO:004816710.015
cytokinetic processGO:003250620.015
regulation of developmental processGO:00507932470.015
regulation of response to stimulusGO:00485832690.015
regulation of nucleocytoplasmic transportGO:004682220.015
small molecule catabolic processGO:004428230.015
regulation of cell communicationGO:00106462320.015
protein secretionGO:000930610.015
cellular response to biotic stimulusGO:007121630.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
chordate embryonic developmentGO:00430092710.015
sequestering of metal ionGO:005123830.015
positive regulation of cell activationGO:005086710.015
regulation of multicellular organismal processGO:00512392770.015
nucleoside monophosphate catabolic processGO:000912540.015
positive regulation of purine nucleotide catabolic processGO:003312310.014
negative regulation of sequestering of calcium ionGO:005128340.014
endosomal transportGO:001619720.014
organelle fusionGO:004828430.014
synaptic vesicle localizationGO:009747910.014
mitochondrial transportGO:000683920.014
spermatid developmentGO:000728620.014
cell cycle g1 s phase transitionGO:004484310.014
carbohydrate homeostasisGO:003350010.014
single organism organelle organizationGO:19025891990.014
Human
digestive tract developmentGO:00485652650.014
peptide transportGO:001583310.014
peptide metabolic processGO:000651810.014
b cell activationGO:004211320.014
lateral inhibitionGO:004633110.014
germ line stem cell maintenanceGO:003071820.014
retina development in camera type eyeGO:00600411460.014
regionalizationGO:00030022740.014
positive regulation of dna metabolic processGO:005105410.014
digestive tract morphogenesisGO:00485462310.014
growthGO:00400071740.014
cellular component biogenesisGO:00440851780.014
regulation of intracellular protein transportGO:003315730.014
phagocytosis engulfmentGO:000691110.014
cellular response to chemical stimulusGO:00708871570.014
response to uvGO:000941130.014
sequestering of calcium ionGO:005120830.014
response to glucoseGO:000974930.014
membrane fusionGO:006102520.014
regulation of multicellular organismal developmentGO:20000262230.014
blood vessel developmentGO:00015682460.014
system processGO:00030081850.014
somatic muscle developmentGO:000752540.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
positive regulation of cytoskeleton organizationGO:005149530.014
glucose homeostasisGO:004259310.014
cellular response to molecule of bacterial originGO:007121930.014
negative regulation of protein transportGO:005122430.013
positive regulation of cellular processGO:00485222010.013
membrane invaginationGO:001032410.013
positive regulation of nucleotide catabolic processGO:003081310.013
homeostasis of number of cellsGO:0048872620.013
eye morphogenesisGO:00485921440.013
mononuclear cell proliferationGO:003294310.013
regulation of sequestering of calcium ionGO:005128240.013
regulation of inflammatory responseGO:005072720.013
regulation of jak stat cascadeGO:004642530.013
lymphocyte proliferationGO:004665110.013
regulation of protein localization to nucleusGO:190018020.013
regulation of calcium ion transportGO:005192420.013
cellular response to light stimulusGO:007148240.013
regulation of ion transmembrane transporter activityGO:003241220.013
cell morphogenesis involved in differentiationGO:00009041950.013
regulation of transporter activityGO:003240920.013
cell substrate adhesionGO:003158940.013
microtubule organizing center organizationGO:003102310.013
cellular response to starvationGO:000926710.013
post embryonic organ developmentGO:004856940.013
tissue remodelingGO:004877140.013
regulation of gtpase activityGO:004308720.013
sensory organ morphogenesisGO:00905962000.013
axonogenesisGO:00074091520.013
meiotic chromosome segregationGO:004513230.013
positive regulation of gtp catabolic processGO:003312610.013
peptidyl serine modificationGO:001820920.013
heart developmentGO:00075073130.013
regulation of gtp catabolic processGO:003312420.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
cellular protein modification processGO:00064641000.013
development of primary female sexual characteristicsGO:004654540.013
protein stabilizationGO:005082120.013
cytoplasm organizationGO:000702840.013
cellular response to radiationGO:007147840.013
establishment of synaptic vesicle localizationGO:009748010.012
symbiosis encompassing mutualism through parasitismGO:004440340.012
negative regulation of mapk cascadeGO:004340940.012
interspecies interaction between organismsGO:004441940.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
neuron projection developmentGO:00311751800.012
amino acid transportGO:000686520.012
negative regulation of cytokine productionGO:000181810.012
cellular response to organic substanceGO:00713101050.012
production of molecular mediator of immune responseGO:000244020.012
oocyte anterior posterior axis specificationGO:000731440.012
positive regulation of chromosome organizationGO:200125210.012
embryo development ending in birth or egg hatchingGO:00097922710.012
regulation of protein targetingGO:190353320.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of cell differentiationGO:00455951420.012
synaptic vesicle transportGO:004848910.012
protein polymerizationGO:005125840.012
positive regulation of secretionGO:005104710.012
developmental growthGO:00485891660.012
establishment of protein localization to plasma membraneGO:009000210.012
negative regulation of macromolecule metabolic processGO:0010605760.012
positive regulation of gtpase activityGO:004354710.012
organic acid catabolic processGO:001605430.012
release of sequestered calcium ion into cytosolGO:005120930.012
camera type eye morphogenesisGO:00485931080.012
intracellular mrna localizationGO:000829810.012
regulation of neurotransmitter transportGO:005158810.012
positive regulation of immune effector processGO:000269930.012
macromolecule modificationGO:00434121110.012
muscle organ developmentGO:00075171010.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
female gonad developmentGO:000858540.012
single organism membrane fusionGO:004480120.012
positive regulation of chromatin modificationGO:190331010.012
mesenchyme developmentGO:00604851270.012
neuroblast proliferationGO:000740520.012
cellular component disassemblyGO:002241110.012
positive regulation of secretion by cellGO:190353210.012
regulation of epithelial cell proliferationGO:005067830.012
ion transmembrane transportGO:0034220910.012
negative regulation of secretionGO:005104820.012
cellular respirationGO:004533330.011
lipid homeostasisGO:005508830.011
specification of symmetryGO:00097992040.011
gastrulationGO:00073692080.011
neuron projection morphogenesisGO:00488121610.011
protein homooligomerizationGO:005126030.011
peptidyl serine phosphorylationGO:001810510.011
neuromuscular synaptic transmissionGO:000727420.011
response to nutrientGO:000758430.011
regulation of protein import into nucleusGO:004230620.011
regulation of dendrite developmentGO:005077330.011
positive regulation of nucleoside metabolic processGO:004597910.011
multi organism processGO:00517041340.011
multi organism cellular processGO:004476420.011
centrosome organizationGO:005129710.011
brain developmentGO:00074202930.011
cation transportGO:0006812810.011
head developmentGO:00603223030.011
positive regulation of map kinase activityGO:004340630.011
actin filament polymerizationGO:003004120.011
actin polymerization or depolymerizationGO:000815420.011
positive regulation of macromolecule metabolic processGO:0010604930.011
response to other organismGO:0051707970.011
secondary metabolic processGO:001974830.011
protein modification processGO:00362111000.011
protein dephosphorylationGO:000647030.011
er to golgi vesicle mediated transportGO:000688810.011
positive regulation of metabolic processGO:00098931080.011
negative regulation of metabolic processGO:0009892860.011
vacuolar transportGO:000703420.011
ion transportGO:00068111140.011
nuclear exportGO:005116810.011
ameboidal type cell migrationGO:00016671430.011
regulation of neurotransmitter secretionGO:004692810.011
regulation of neuronal synaptic plasticityGO:004816810.011
response to external biotic stimulusGO:0043207970.011
regulation of autophagyGO:001050630.011
deathGO:00162651210.011
cytosolic calcium ion transportGO:006040130.011
mitotic cytokinesisGO:000028130.011
response to biotic stimulusGO:0009607970.011
anterior posterior pattern specificationGO:00099521520.011
positive regulation of lymphocyte mediated immunityGO:000270810.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
pancreas developmentGO:0031016840.011
negative regulation of response to stimulusGO:00485851040.011
developmental programmed cell deathGO:001062340.011
macromolecular complex disassemblyGO:003298410.011
regulation of circadian rhythmGO:004275240.011
negative regulation of defense responseGO:003134820.010
g1 s transition of mitotic cell cycleGO:000008210.010
positive regulation of leukocyte differentiationGO:190210710.010
regulation of dendrite morphogenesisGO:004881430.010
embryonic organ morphogenesisGO:00485622740.010
protein complex disassemblyGO:004324110.010
response to organic substanceGO:00100331530.010
regulation of nervous system developmentGO:0051960900.010
regulation of transmembrane transporter activityGO:002289820.010
stem cell developmentGO:0048864820.010
striated muscle cell developmentGO:00550021080.010
determination of bilateral symmetryGO:00098552040.010
negative regulation of secretion by cellGO:190353120.010
catecholamine metabolic processGO:000658420.010
phosphate containing compound metabolic processGO:00067961080.010
cell morphogenesis involved in neuron differentiationGO:00486671630.010
cell cycle arrestGO:000705010.010
cortical cytoskeleton organizationGO:003086510.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
negative regulation of multi organism processGO:004390130.010
regulation of cellular carbohydrate metabolic processGO:001067540.010
positive regulation of histone modificationGO:003105810.010

zgc:103506 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.045
nervous system diseaseDOID:86300.020
musculoskeletal system diseaseDOID:1700.018
disease of metabolismDOID:001466700.017
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.015
immune system diseaseDOID:291400.014
inherited metabolic disorderDOID:65500.012
muscular diseaseDOID:008000000.011