Danio rerio

35 known processes

mvp

major vault protein

(Aliases: cb771,wu:fb52b05,wu:fc02g01)

mvp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823530.432
p38mapk cascadeGO:003806610.335
organic substance biosynthetic processGO:19015762890.299
regulation of p38mapk cascadeGO:190074410.296
somite developmentGO:0061053960.258
negative regulation of cellular processGO:00485232830.251
Human
response to stressGO:00069502630.251
immune system processGO:00023762410.243
cellular biosynthetic processGO:00442492860.236
response to antibioticGO:004667710.231
regulation of biological qualityGO:00650082630.216
heterocycle metabolic processGO:00464832900.200
cellular aromatic compound metabolic processGO:00067252950.182
apoptotic processGO:00069151160.182
hematopoietic or lymphoid organ developmentGO:00485341910.173
regulation of response to oxidative stressGO:190288220.171
response to organic substanceGO:00100331530.163
single organism metabolic processGO:00447102170.146
Mouse
response to external stimulusGO:00096052640.142
protein metabolic processGO:00195381830.141
Human Mouse
chordate embryonic developmentGO:00430092710.139
response to ketoneGO:190165410.134
regulation of macromolecule metabolic processGO:00602553170.128
Human
deathGO:00162651210.117
segmentationGO:0035282970.117
positive regulation of cellular processGO:00485222010.117
regulation of response to stimulusGO:00485832690.116
sensory organ developmentGO:00074233930.115
regulation of metabolic processGO:00192223590.114
Human
eye developmentGO:00016542770.112
positive regulation of macromolecule metabolic processGO:0010604930.112
regulation of nitrogen compound metabolic processGO:00511712510.111
cell deathGO:00082191210.111
anterior posterior pattern specificationGO:00099521520.109
nitrogen compound metabolic processGO:00068073190.106
cellular macromolecule biosynthetic processGO:00346452240.103
neuron developmentGO:00486662620.102
response to chemicalGO:00422213200.101
response to inorganic substanceGO:0010035380.098
generation of neuronsGO:00486993850.097
regulation of signalingGO:00230512350.093
Human
regulation of response to stressGO:0080134360.092
agingGO:000756820.091
regulation of cellular metabolic processGO:00313233200.088
Human
regulation of primary metabolic processGO:00800903110.085
Human
epithelial cell differentiationGO:00308551160.085
positive regulation of biological processGO:00485182530.082
cellular macromolecule metabolic processGO:00442603910.081
Human
regulation of gene expressionGO:00104682650.080
somitogenesisGO:0001756870.080
signal transductionGO:00071654550.078
Human
positive regulation of metabolic processGO:00098931080.077
brain developmentGO:00074202930.076
neuron projection developmentGO:00311751800.076
hemopoiesisGO:00300971830.076
regulation of establishment of protein localizationGO:007020140.073
cofactor metabolic processGO:0051186150.073
embryonic hemopoiesisGO:0035162530.073
cognitionGO:005089010.071
immune system developmentGO:00025201910.065
regulation of apoptotic processGO:0042981980.064
positive regulation of nitrogen compound metabolic processGO:0051173690.064
tube morphogenesisGO:00352393490.063
axonogenesisGO:00074091520.062
response to hexoseGO:000974630.061
response to metal ionGO:0010038340.061
axon developmentGO:00615641660.061
positive regulation of stress activated mapk cascadeGO:003287430.060
regulation of bindingGO:005109830.060
biosynthetic processGO:00090582940.057
cellular response to stressGO:0033554620.055
positive regulation of transportGO:005105020.054
regulation of nucleocytoplasmic transportGO:004682220.054
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.054
regulation of intracellular protein transportGO:003315730.053
phosphorus metabolic processGO:00067931090.053
Human
heterocycle biosynthetic processGO:00181302150.053
organic cyclic compound biosynthetic processGO:19013622230.053
central nervous system developmentGO:00074173870.052
organonitrogen compound biosynthetic processGO:1901566470.050
positive regulation of jnk cascadeGO:004633030.050
hindbrain developmentGO:0030902910.050
response to organic cyclic compoundGO:0014070510.050
response to carbohydrateGO:000974330.049
system processGO:00030081850.049
nucleobase containing compound metabolic processGO:00061392740.048
cellular nitrogen compound biosynthetic processGO:00442712180.047
phosphate containing compound metabolic processGO:00067961080.047
Human
angiogenesisGO:00015251580.047
gene expressionGO:00104672520.046
regulation of transcription from rna polymerase ii promoterGO:00063571140.045
head developmentGO:00603223030.045
camera type eye developmentGO:00430102220.045
protein localization to plasma membraneGO:007265910.044
extrinsic apoptotic signaling pathwayGO:009719130.044
regulation of macromolecule biosynthetic processGO:00105562250.043
lipid storageGO:001991510.043
positive regulation of signal transductionGO:0009967560.043
embryo development ending in birth or egg hatchingGO:00097922710.043
intracellular signal transductionGO:0035556850.042
macromolecule modificationGO:00434121110.042
Human
fatty acid transportGO:001590810.042
regulation of protein import into nucleusGO:004230620.042
protein modification processGO:00362111000.041
Human
regulation of developmental processGO:00507932470.040
myeloid cell differentiationGO:0030099860.040
regulation of cell communicationGO:00106462320.040
regulation of signal transductionGO:00099662250.040
adult behaviorGO:003053420.040
regulation of intracellular signal transductionGO:1902531570.039
neuron projection morphogenesisGO:00488121610.039
rna metabolic processGO:00160702190.039
response to amino acidGO:004320020.039
negative regulation of biological processGO:00485193040.039
Human
regulation of multicellular organismal processGO:00512392770.039
response to cadmium ionGO:0046686140.038
cellular sodium ion homeostasisGO:000688310.038
blood vessel morphogenesisGO:00485142160.038
eye morphogenesisGO:00485921440.038
response to woundingGO:00096111160.037
primitive hemopoiesisGO:0060215270.037
cellular protein metabolic processGO:00442671290.036
Human
response to glucocorticoidGO:005138410.036
regulation of cell shapeGO:000836010.036
response to glucoseGO:000974930.036
maintenance of epithelial cell apical basal polarityGO:004519950.036
phosphorylationGO:0016310690.036
Human
organic cyclic compound metabolic processGO:19013603010.036
single organism localizationGO:19025782250.035
protein stabilizationGO:005082120.035
cellular protein modification processGO:00064641000.035
Human
nuclear transportGO:005116940.034
positive regulation of signalingGO:0023056560.034
negative regulation of kinase activityGO:003367340.033
Human
regulation of cell deathGO:00109411030.033
behaviorGO:0007610740.032
embryonic organ developmentGO:00485683810.032
positive regulation of cellular metabolic processGO:0031325940.032
nucleic acid templated transcriptionGO:00976591810.031
retina development in camera type eyeGO:00600411460.031
morphogenesis of an epitheliumGO:00020093330.031
regionalizationGO:00030022740.031
regulation of striated muscle contractionGO:000694220.031
regulation of cellular response to oxidative stressGO:190040720.031
single fertilizationGO:000733830.031
regulation of epithelial cell proliferationGO:005067830.031
organic acid metabolic processGO:0006082310.030
glucose homeostasisGO:004259310.030
macromolecule biosynthetic processGO:00090592270.030
regulation of protein transportGO:005122330.030
long chain fatty acid transportGO:001590910.030
organonitrogen compound metabolic processGO:1901564740.030
cell projection organizationGO:00300302840.030
neuron projection regenerationGO:0031102160.030
biological adhesionGO:0022610400.030
regulation of nucleic acid templated transcriptionGO:19035062130.030
hatchingGO:003518840.029
osteoclast developmentGO:003603510.029
camera type eye morphogenesisGO:00485931080.029
oxoacid metabolic processGO:0043436310.029
response to oxygen containing compoundGO:1901700550.029
protein importGO:001703830.028
maintenance of locationGO:005123540.028
regulation of protein metabolic processGO:0051246560.028
Human
ameboidal type cell migrationGO:00016671430.028
regulation of localizationGO:00328791040.027
skin developmentGO:0043588540.027
regulation of protein localization to nucleusGO:190018020.027
ectodermal cell fate specificationGO:000171520.027
regulation of blood pressureGO:000821710.027
sensory organ morphogenesisGO:00905962000.027
regulation of rna biosynthetic processGO:20011412130.027
positive regulation of apoptotic signaling pathwayGO:200123510.027
nucleobase containing compound biosynthetic processGO:00346542050.027
regulation of cellular amino acid metabolic processGO:000652100.026
regulation of metal ion transportGO:001095940.026
retina morphogenesis in camera type eyeGO:0060042790.025
response to oxygen levelsGO:0070482250.025
regulation of transcription dna templatedGO:00063552130.025
long chain fatty acid metabolic processGO:000167610.025
taxisGO:00423301090.025
response to monosaccharideGO:003428430.025
cellular response to organic substanceGO:00713101050.025
response to lipidGO:0033993600.025
regulation of cellular biosynthetic processGO:00313262450.024
programmed cell deathGO:00125011190.024
cell morphogenesis involved in differentiationGO:00009041950.024
multicellular organism growthGO:003526440.024
response to corticosteroidGO:003196010.024
regulation of inflammatory responseGO:005072720.024
cellular amide metabolic processGO:004360340.023
intestinal absorptionGO:005089220.023
aromatic compound biosynthetic processGO:00194382170.023
cell motilityGO:00488702440.023
response to nutrientGO:000758430.023
establishment of protein localization to organelleGO:007259440.023
cellular component movementGO:00069283350.023
transcription dna templatedGO:00063511810.022
negative regulation of cell deathGO:0060548600.022
organism emergence from protective structureGO:007168440.022
cell surface receptor signaling pathwayGO:00071663250.022
Human
regulation of neurogenesisGO:0050767870.022
morphogenesis of an epithelial sheetGO:0002011490.022
epidermis developmentGO:0008544480.022
regulation of anatomical structure morphogenesisGO:00226031300.022
regulation of sodium ion transportGO:000202820.022
protein import into nucleusGO:000660630.021
cell morphogenesisGO:00009022890.021
establishment or maintenance of bipolar cell polarityGO:0061245120.021
regulation of nucleotide catabolic processGO:003081120.021
response to abiotic stimulusGO:00096281220.021
blood circulationGO:0008015870.021
regulation of protein targetingGO:190353320.021
cellular response to biotic stimulusGO:007121630.020
positive regulation of catabolic processGO:000989640.020
cellular response to chemical stimulusGO:00708871570.020
regulation of cytoplasmic transportGO:190364940.020
actin filament based movementGO:003004810.020
positive regulation of cellular catabolic processGO:003133130.020
nuclear importGO:005117030.020
multi organism processGO:00517041340.020
circulatory system processGO:0003013870.020
regulation of multicellular organism growthGO:004001440.019
activation of mapkkk activityGO:000018510.019
cell projection morphogenesisGO:00488582440.019
cellular response to external stimulusGO:007149620.019
hemoglobin biosynthetic processGO:004254180.019
negative regulation of protein kinase activityGO:000646940.019
Human
fertilizationGO:000956630.019
cell migrationGO:00164772370.019
locomotory behaviorGO:0007626340.019
rna biosynthetic processGO:00327741810.019
multicellular organism reproductionGO:0032504350.018
negative regulation of protein phosphorylationGO:000193340.018
Human
cellular response to oxygen levelsGO:007145310.018
negative regulation of nucleocytoplasmic transportGO:004682320.018
heme metabolic processGO:004216890.018
protein targeting to nucleusGO:004474430.018
muscle tissue developmentGO:00605371100.018
peptide metabolic processGO:000651810.018
gtp catabolic processGO:000618420.018
regulation of cytokine productionGO:000181730.018
anion transportGO:0006820380.018
positive regulation of cellular amine metabolic processGO:003324000.018
peptidyl serine modificationGO:001820920.018
membrane fusionGO:006102520.018
mitochondrion organizationGO:000700540.018
cell proliferationGO:0008283800.018
Mouse
cellular nitrogen compound metabolic processGO:00346412900.018
epithelial tube morphogenesisGO:00605621480.018
regulation of protein catabolic processGO:004217610.017
regulation of nucleobase containing compound metabolic processGO:00192192500.017
centrosome cycleGO:000709810.017
localization of cellGO:00516742440.017
ion transportGO:00068111140.017
actin polymerization or depolymerizationGO:000815420.017
guanosine containing compound metabolic processGO:190106840.017
negative regulation of epithelial cell proliferationGO:005068010.017
larval developmentGO:000216420.017
meiotic nuclear divisionGO:000712640.017
cellular protein catabolic processGO:004425740.017
mesenchyme developmentGO:00604851270.016
negative regulation of cellular metabolic processGO:0031324770.016
Human
regulation of programmed cell deathGO:00430671010.016
neurotransmitter secretionGO:000726920.016
mesoderm developmentGO:0007498880.016
regulation of cellular protein metabolic processGO:0032268520.016
Human
regulation of calcium ion transportGO:005192420.016
regulation of catalytic activityGO:0050790550.016
Human
regulation of rna metabolic processGO:00512522240.016
carboxylic acid metabolic processGO:0019752220.016
macromolecule localizationGO:0033036540.016
cofactor biosynthetic processGO:0051188100.016
multicellular organismal reproductive processGO:0048609350.016
cellular response to toxic substanceGO:009723710.016
transcription from rna polymerase ii promoterGO:0006366800.016
cellular component morphogenesisGO:00329893360.016
multi organism reproductive processGO:0044703360.016
establishment of protein localization to plasma membraneGO:009000210.016
proteolysis involved in cellular protein catabolic processGO:005160330.016
carbohydrate derivative metabolic processGO:1901135610.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
peptide transportGO:001583310.016
neurotransmitter transportGO:000683620.016
erythrocyte homeostasisGO:0034101550.015
negative regulation of apoptotic processGO:0043066550.015
multicellular organismal metabolic processGO:004423620.015
small molecule metabolic processGO:0044281770.015
i kappab kinase nf kappab signalingGO:000724940.015
tyrosine phosphorylation of stat proteinGO:000726010.015
regulation of cellular macromolecule biosynthetic processGO:20001122220.015
regulation of nucleoside metabolic processGO:000911820.015
dorsal motor nucleus of vagus nerve developmentGO:002174440.015
synaptic growth at neuromuscular junctionGO:005112420.015
gtp metabolic processGO:004603940.015
meiotic cell cycle processGO:190304630.015
adherens junction organizationGO:003433240.015
response to drugGO:004249330.015
beta amyloid metabolic processGO:005043510.014
amyloid precursor protein metabolic processGO:004298210.014
regulation of cell motilityGO:2000145460.014
vasculature developmentGO:00019442780.014
energy reserve metabolic processGO:000611220.014
sodium ion transportGO:0006814240.014
cellular response to starvationGO:000926710.014
developmental growthGO:00485891660.014
cardiac conductionGO:006133730.014
regulation of cellular response to stressGO:0080135200.014
mitochondrial transportGO:000683920.014
regulation of oxidative stress induced cell deathGO:190320120.014
negative regulation of metabolic processGO:0009892860.014
Human
regulation of dendrite developmentGO:005077330.014
regulation of multicellular organismal developmentGO:20000262230.014
chromosome organization involved in meiosisGO:007019210.014
single organism cell adhesionGO:0098602290.014
protein phosphorylationGO:0006468470.014
Human
homeostatic processGO:00425921420.014
positive regulation of cell deathGO:0010942290.014
cytokinesisGO:000091030.014
response to alcoholGO:0097305140.014
medulla oblongata developmentGO:002155040.013
carbohydrate homeostasisGO:003350010.013
cellular response to lipopolysaccharideGO:007122230.013
hemoglobin metabolic processGO:0020027120.013
apoptotic signaling pathwayGO:0097190230.013
regulation of cellular protein catabolic processGO:190336210.013
digestive tract morphogenesisGO:00485462310.013
cell part morphogenesisGO:00329902460.013
beta amyloid formationGO:003420510.013
heart contractionGO:0060047710.013
toxin transportGO:190199820.013
regulation of cardiac muscle cell contractionGO:008600410.013
positive regulation of protein metabolic processGO:0051247230.013
mononuclear cell proliferationGO:003294310.013
single organism membrane fusionGO:004480120.013
regulation of actin filament based movementGO:190311510.013
response to vitaminGO:003327330.013
regulation of protein complex assemblyGO:004325430.013
positive regulation of nucleoside metabolic processGO:004597910.013
purine nucleoside monophosphate catabolic processGO:000912840.013
positive regulation of gene expressionGO:0010628710.013
tube formationGO:0035148250.013
erythrocyte differentiationGO:0030218540.013
regenerationGO:0031099910.012
posterior lateral line developmentGO:0048916380.012
regulation of cell differentiationGO:00455951420.012
regulation of synaptic plasticityGO:004816710.012
regulation of cell migrationGO:0030334400.012
establishment of localizationGO:00512342440.012
cell death in response to oxidative stressGO:003647320.012
regulation of muscle contractionGO:000693730.012
regulation of protein polymerizationGO:003227120.012
collagen metabolic processGO:003296320.012
negative regulation of cytoplasmic transportGO:190365020.012
myeloid cell homeostasisGO:0002262560.012
single organismal cell cell adhesionGO:0016337290.012
heart morphogenesisGO:00030071560.012
response to external biotic stimulusGO:0043207970.012
response to hydrogen peroxideGO:004254230.012
positive regulation of response to stimulusGO:0048584800.012
single organism nuclear importGO:190259330.012
regulation of gtp catabolic processGO:003312420.012
negative regulation of blood vessel endothelial cell migrationGO:004353710.012
nucleic acid metabolic processGO:00903042440.012
hormone transportGO:000991420.012
single organism carbohydrate metabolic processGO:0044723120.012
cellular carbohydrate metabolic processGO:004426240.012
positive regulation of cellular component biogenesisGO:004408930.011
regulation of phosphorylationGO:0042325260.011
Human
blood vessel developmentGO:00015682460.011
regulation of jak stat cascadeGO:004642530.011
metal ion transportGO:0030001580.011
cytoskeleton dependent cytokinesisGO:006164030.011
carbohydrate metabolic processGO:0005975120.011
regulation of synapse assemblyGO:005196330.011
regulation of reactive oxygen species metabolic processGO:200037720.011
action potentialGO:0001508190.011
liver developmentGO:0001889960.011
regulation of multicellular organismal metabolic processGO:004424620.011
extracellular structure organizationGO:0043062270.011
carbohydrate derivative biosynthetic processGO:1901137430.011
positive regulation of biosynthetic processGO:0009891680.011
cellular amino acid metabolic processGO:000652070.011
cellular response to endogenous stimulusGO:0071495680.011
organelle organizationGO:00069962270.011
negative regulation of intracellular protein transportGO:009031730.011
autophagyGO:000691440.011
regulation of neurotransmitter secretionGO:004692810.011
homeostasis of number of cellsGO:0048872620.011
epithelial cell morphogenesisGO:000338220.011
positive regulation of gtp catabolic processGO:003312610.011
negative regulation of cytokine productionGO:000181810.011
negative regulation of multi organism processGO:004390130.010
lamellipodium assemblyGO:003003210.010
response to steroid hormoneGO:0048545350.010
maternal determination of anterior posterior axis embryoGO:000835840.010
positive regulation of blood circulationGO:190352420.010
embryonic pattern specificationGO:0009880440.010
neural tube developmentGO:0021915620.010
regulation of locomotionGO:0040012550.010
protein localization to nucleusGO:003450430.010
nerve developmentGO:0021675450.010
regulation of response to external stimulusGO:0032101310.010
transportGO:00068102200.010
centrosome organizationGO:005129710.010
sex determinationGO:000753010.010
cellular catabolic processGO:0044248270.010
regulation of i kappab kinase nf kappab signalingGO:004312240.010
negative regulation of intracellular transportGO:003238730.010

mvp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.059
musculoskeletal system diseaseDOID:1700.059
myopathyDOID:42300.059
muscle tissue diseaseDOID:6600.059
disease of anatomical entityDOID:700.059
heart diseaseDOID:11400.059
cardiomyopathyDOID:005070000.059
muscular diseaseDOID:008000000.059
intrinsic cardiomyopathyDOID:006003600.028
nervous system diseaseDOID:86300.024
lysosomal storage diseaseDOID:321100.015
inherited metabolic disorderDOID:65500.015
disease of metabolismDOID:001466700.015