Danio rerio

31 known processes

enpp1

ectonucleotide pyrophosphatase/phosphodiesterase 1

(Aliases: zgc:136238,MGC136238,si:ch211-142e24.2)

enpp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal system developmentGO:00015011810.731
rna biosynthetic processGO:00327741810.283
hematopoietic or lymphoid organ developmentGO:00485341910.267
aromatic compound biosynthetic processGO:00194382170.266
regulation of cellular biosynthetic processGO:00313262450.198
larval developmentGO:000216420.194
nucleic acid templated transcriptionGO:00976591810.173
regulation of metabolic processGO:00192223590.159
tissue remodelingGO:004877140.159
embryonic organ developmentGO:00485683810.157
regulation of biological qualityGO:00650082630.149
regulation of cell communicationGO:00106462320.146
generation of neuronsGO:00486993850.139
regulation of nucleic acid templated transcriptionGO:19035062130.134
transcription dna templatedGO:00063511810.132
regulation of gene expressionGO:00104682650.122
organic cyclic compound biosynthetic processGO:19013622230.121
embryo development ending in birth or egg hatchingGO:00097922710.119
positive regulation of cellular processGO:00485222010.117
response to chemicalGO:00422213200.116
regulation of cellular macromolecule biosynthetic processGO:20001122220.116
chordate embryonic developmentGO:00430092710.110
cellular macromolecule biosynthetic processGO:00346452240.109
negative regulation of biological processGO:00485193040.107
positive regulation of biological processGO:00485182530.107
regulation of establishment of protein localizationGO:007020140.104
protein localization to nucleusGO:003450430.102
cellular aromatic compound metabolic processGO:00067252950.099
regulation of rna metabolic processGO:00512522240.096
camera type eye developmentGO:00430102220.096
regulation of macromolecule biosynthetic processGO:00105562250.096
rna metabolic processGO:00160702190.094
organic substance biosynthetic processGO:19015762890.086
sensory organ developmentGO:00074233930.086
hemopoiesisGO:00300971830.086
gene expressionGO:00104672520.084
regulation of macromolecule metabolic processGO:00602553170.084
regulation of synapse assemblyGO:005196330.082
cellular localizationGO:0051641970.081
regulation of multicellular organism growthGO:004001440.081
immune system developmentGO:00025201910.078
nucleic acid metabolic processGO:00903042440.077
positive regulation of signalingGO:0023056560.073
signal transductionGO:00071654550.071
regulation of endothelial cell proliferationGO:000193610.070
biosynthetic processGO:00090582940.069
transcription from rna polymerase ii promoterGO:0006366800.068
regionalizationGO:00030022740.068
response to external stimulusGO:00096052640.067
cell surface receptor signaling pathwayGO:00071663250.067
regulation of signalingGO:00230512350.067
central nervous system developmentGO:00074173870.065
nitrogen compound metabolic processGO:00068073190.065
maintenance of locationGO:005123540.064
multicellular organism growthGO:003526440.064
nucleobase containing compound metabolic processGO:00061392740.063
mechanosensory behaviorGO:000763820.063
immune system processGO:00023762410.060
collagen fibril organizationGO:003019910.060
heterocycle biosynthetic processGO:00181302150.060
glycoprotein metabolic processGO:0009100230.060
embryonic organ morphogenesisGO:00485622740.060
heterocycle metabolic processGO:00464832900.060
cartilage developmentGO:0051216960.059
cell morphogenesis involved in differentiationGO:00009041950.059
organic cyclic compound metabolic processGO:19013603010.058
regulation of transcription dna templatedGO:00063552130.057
protein heterooligomerizationGO:005129110.056
macromolecule biosynthetic processGO:00090592270.054
regulation of primary metabolic processGO:00800903110.054
homeostatic processGO:00425921420.053
positive regulation of cytosolic calcium ion concentrationGO:000720440.051
positive regulation of nitrogen compound metabolic processGO:0051173690.051
positive regulation of cellular component biogenesisGO:004408930.050
regulation of nitrogen compound metabolic processGO:00511712510.050
embryonic skeletal system morphogenesisGO:0048704930.048
cellular nitrogen compound metabolic processGO:00346412900.048
regulation of rna biosynthetic processGO:20011412130.047
cellular biosynthetic processGO:00442492860.047
regulation of cellular metabolic processGO:00313233200.047
regulation of cytoplasmic transportGO:190364940.046
regulation of epithelial cell proliferationGO:005067830.046
regulation of nucleobase containing compound metabolic processGO:00192192500.045
positive regulation of catabolic processGO:000989640.044
carbohydrate derivative metabolic processGO:1901135610.044
release of sequestered calcium ion into cytosolGO:005120930.043
angiogenesisGO:00015251580.043
chondroitin sulfate metabolic processGO:003020420.043
cellular response to chemical stimulusGO:00708871570.041
carbohydrate derivative biosynthetic processGO:1901137430.041
regulation of bindingGO:005109830.041
establishment of protein localization to organelleGO:007259440.041
regulation of synapse organizationGO:005080730.041
cell cycle arrestGO:000705010.040
cellular nitrogen compound biosynthetic processGO:00442712180.040
determination of ventral identityGO:0048264210.040
glycoprotein biosynthetic processGO:0009101210.039
embryonic skeletal system developmentGO:0048706970.039
response to fluid shear stressGO:003440520.039
negative regulation of sequestering of calcium ionGO:005128340.039
cellular macromolecule metabolic processGO:00442603910.038
regulation of reproductive processGO:200024140.038
embryonic hemopoiesisGO:0035162530.038
protein metabolic processGO:00195381830.037
cellular amino acid metabolic processGO:000652070.037
eye developmentGO:00016542770.037
regulation of protein transportGO:005122330.037
calcium ion transport into cytosolGO:006040230.037
proteoglycan metabolic processGO:0006029140.037
regulation of multicellular organismal developmentGO:20000262230.037
negative regulation of epithelial cell proliferationGO:005068010.036
single organism nuclear importGO:190259330.036
negative regulation of rna metabolic processGO:0051253480.036
small molecule metabolic processGO:0044281770.035
caudal fin developmentGO:003333690.035
morphogenesis of an epitheliumGO:00020093330.035
positive regulation of metabolic processGO:00098931080.035
ion homeostasisGO:0050801410.034
single organism transportGO:00447652060.034
intramembranous ossificationGO:000195730.034
regulation of biosynthetic processGO:00098892500.034
hatchingGO:003518840.034
ion transmembrane transportGO:0034220910.034
medial fin morphogenesisGO:0035141140.034
mononuclear cell proliferationGO:003294310.033
chemical homeostasisGO:0048878490.033
positive regulation of canonical wnt signaling pathwayGO:009026340.033
single organism metabolic processGO:00447102170.033
transportGO:00068102200.033
regulation of intracellular protein transportGO:003315730.032
response to stressGO:00069502630.032
regulation of signal transductionGO:00099662250.032
positive regulation of cell activationGO:005086710.032
cellular response to extracellular stimulusGO:003166820.032
positive regulation of endothelial cell proliferationGO:000193810.032
nucleobase containing compound biosynthetic processGO:00346542050.032
central nervous system neuron differentiationGO:0021953740.031
regulation of retinoic acid biosynthetic processGO:190005260.031
positive regulation of nucleobase containing compound metabolic processGO:0045935690.031
positive regulation of rna biosynthetic processGO:1902680570.031
specification of symmetryGO:00097992040.031
convergent extensionGO:00600261180.031
positive regulation of response to stimulusGO:0048584800.031
cell matrix adhesionGO:000716040.030
negative regulation of signalingGO:0023057960.030
regulation of protein catabolic processGO:004217610.029
biomineral tissue developmentGO:0031214130.029
embryonic medial fin morphogenesisGO:003512260.029
negative regulation of cellular processGO:00485232830.029
regulation of protein import into nucleusGO:004230620.029
regulation of nervous system developmentGO:0051960900.029
intracellular transportGO:0046907320.028
regulation of chondrocyte differentiationGO:003233010.028
dorsal ventral pattern formationGO:00099531250.028
cellular protein metabolic processGO:00442671290.028
chondroitin sulfate biosynthetic processGO:003020620.027
dopamine metabolic processGO:004241720.027
synaptic growth at neuromuscular junctionGO:005112420.027
agingGO:000756820.026
multi organism processGO:00517041340.026
heart loopingGO:0001947940.026
regulation of immune system processGO:0002682340.026
positive regulation of cellular metabolic processGO:0031325940.026
blood vessel morphogenesisGO:00485142160.026
regulation of autophagyGO:001050630.026
lymphocyte proliferationGO:004665110.025
tissue regenerationGO:0042246740.025
regulation of cell shapeGO:000836010.025
positive regulation of transportGO:005105020.025
organonitrogen compound metabolic processGO:1901564740.025
regulation of protein bindingGO:004339330.025
positive regulation of nucleic acid templated transcriptionGO:1903508570.025
leukocyte proliferationGO:007066110.025
establishment of localizationGO:00512342440.025
chemotaxisGO:00069351040.024
embryonic heart tube developmentGO:00350501330.024
appendage developmentGO:0048736800.024
determination of heart left right asymmetryGO:00613711170.024
protein importGO:001703830.024
developmental growthGO:00485891660.024
stem cell maintenanceGO:001982740.024
cytosolic calcium ion transportGO:006040130.023
negative regulation of cytoplasmic transportGO:190365020.023
embryonic cranial skeleton morphogenesisGO:0048701900.023
regulation of multicellular organismal processGO:00512392770.023
inorganic cation transmembrane transportGO:0098662500.023
response to glucoseGO:000974930.023
regulation of response to stimulusGO:00485832690.023
regulation of nucleoside metabolic processGO:000911820.023
golgi vesicle transportGO:004819330.023
germ line stem cell divisionGO:004207810.023
enzyme linked receptor protein signaling pathwayGO:00071671060.022
medial fin developmentGO:0033338160.022
nucleoside monophosphate catabolic processGO:000912540.022
locomotionGO:00400113130.022
response to drugGO:004249330.022
nephron tubule morphogenesisGO:007207810.022
cellular lipid catabolic processGO:004424230.022
cellular response to organic substanceGO:00713101050.022
cellular component morphogenesisGO:00329893360.022
regenerationGO:0031099910.022
sequestering of calcium ionGO:005120830.022
heart morphogenesisGO:00030071560.022
organelle organizationGO:00069962270.022
determination of dorsal ventral asymmetryGO:0048262340.022
negative regulation of protein localization to nucleusGO:190018120.022
regulation of cellular component organizationGO:0051128860.022
cell morphogenesisGO:00009022890.022
fin regenerationGO:0031101510.022
homeostasis of number of cells within a tissueGO:004887340.021
nuclear transportGO:005116940.021
negative regulation of signal transductionGO:0009968940.021
oxoacid metabolic processGO:0043436310.021
neuron differentiationGO:00301823530.021
blood vessel developmentGO:00015682460.021
positive regulation of secretionGO:005104710.021
cation transmembrane transportGO:0098655650.021
liver developmentGO:0001889960.021
negative regulation of cell communicationGO:0010648960.021
protein import into nucleusGO:000660630.020
cellular response to starvationGO:000926710.020
cellular component movementGO:00069283350.020
positive regulation of transcription dna templatedGO:0045893570.020
stem cell divisionGO:001714510.020
stem cell proliferationGO:007208940.020
maternal determination of anterior posterior axis embryoGO:000835840.020
positive regulation of cellular catabolic processGO:003133130.020
carboxylic acid metabolic processGO:0019752220.019
positive regulation of secretion by cellGO:190353210.019
regulation of sequestering of calcium ionGO:005128240.019
negative regulation of axon extension involved in axon guidanceGO:004884310.019
positive regulation of cellular biosynthetic processGO:0031328680.019
amine metabolic processGO:000930820.019
neuron projection morphogenesisGO:00488121610.019
nephron morphogenesisGO:007202820.019
modification dependent macromolecule catabolic processGO:004363230.019
negative regulation of intracellular protein transportGO:009031730.019
odontogenesis of dentin containing toothGO:004247510.019
nucleocytoplasmic transportGO:000691340.019
positive regulation of rna metabolic processGO:0051254590.019
immunoglobulin mediated immune responseGO:001606430.019
germ line stem cell maintenanceGO:003071820.018
regulation of blood vessel sizeGO:005088020.018
regulation of stem cell differentiationGO:200073640.018
negative regulation of nucleocytoplasmic transportGO:004682320.018
regulation of cellular amino acid metabolic processGO:000652100.018
regulation of transportGO:0051049450.018
negative regulation of protein transportGO:005122430.018
phenol containing compound biosynthetic processGO:004618940.018
negative regulation of dna metabolic processGO:005105340.018
rna localizationGO:000640340.018
ventral spinal cord interneuron fate commitmentGO:006057930.018
bone mineralizationGO:003028290.018
tube morphogenesisGO:00352393490.018
phosphate containing compound metabolic processGO:00067961080.018
positive regulation of biosynthetic processGO:0009891680.018
regulation of cell maturationGO:190342910.018
negative regulation of metabolic processGO:0009892860.017
gastrulationGO:00073692080.017
negative regulation of intracellular transportGO:003238730.017
regulation of anatomical structure morphogenesisGO:00226031300.017
carbohydrate biosynthetic processGO:001605110.017
regulation of nucleocytoplasmic transportGO:004682220.017
embryonic heart tube morphogenesisGO:00031431080.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.017
regulation of protein localization to nucleusGO:190018020.017
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.017
cellular amine metabolic processGO:004410620.017
regulation of tube sizeGO:003515020.017
circulatory system processGO:0003013870.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
regulation of oocyte developmentGO:006028130.017
retinoic acid metabolic processGO:004257390.017
renal tubule morphogenesisGO:006133310.017
purine containing compound metabolic processGO:0072521290.017
cell projection morphogenesisGO:00488582440.017
negative regulation of chemotaxisGO:005092240.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.017
maintenance of gastrointestinal epitheliumGO:003027770.017
tube closureGO:006060610.017
response to monosaccharideGO:003428430.017
primary amino compound metabolic processGO:190116010.016
response to amino acidGO:004320020.016
regulation of cell activationGO:005086510.016
blood circulationGO:0008015870.016
mucopolysaccharide metabolic processGO:190351020.016
cell migrationGO:00164772370.016
mesoderm formationGO:0001707430.016
inorganic ion transmembrane transportGO:0098660570.016
cardiac atrium developmentGO:000323040.016
gtp metabolic processGO:004603940.016
regulation of epithelial to mesenchymal transitionGO:001071730.016
convergent extension involved in gastrulationGO:0060027710.016
regulation of protein complex assemblyGO:004325430.016
hepaticobiliary system developmentGO:0061008980.016
extracellular matrix constituent secretionGO:007027830.016
fin developmentGO:0033333770.016
trigeminal nerve developmentGO:002155930.016
multicellular organismal signalingGO:0035637220.016
rhombomere 5 developmentGO:002157140.016
extracellular structure organizationGO:0043062270.016
brain developmentGO:00074202930.016
embryonic pattern specificationGO:0009880440.016
catecholamine metabolic processGO:000658420.016
determination of bilateral symmetryGO:00098552040.016
ubiquitin dependent protein catabolic processGO:000651130.016
regulation of glial cell differentiationGO:004568540.016
cellular response to nutrient levelsGO:003166920.016
nephron epithelium morphogenesisGO:007208810.016
indole containing compound metabolic processGO:004243020.015
cell morphogenesis involved in neuron differentiationGO:00486671630.015
negative regulation of catabolic processGO:000989530.015
regulation of hormone secretionGO:004688320.015
ossificationGO:0001503230.015
meiotic nuclear divisionGO:000712640.015
skeletal system morphogenesisGO:00487051020.015
chemosensory behaviorGO:000763510.015
digestive system developmentGO:00551232890.015
wound healingGO:0042060900.015
cytoplasm organizationGO:000702840.015
anterior posterior pattern specificationGO:00099521520.015
synaptic vesicle localizationGO:009747910.015
axis specificationGO:0009798430.015
axon developmentGO:00615641660.015
single organism localizationGO:19025782250.015
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.015
atp catabolic processGO:000620040.014
immune responseGO:0006955280.014
cellular biogenic amine metabolic processGO:000657620.014
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.014
regulation of neural precursor cell proliferationGO:200017730.014
negative regulation of protein import into nucleusGO:004230820.014
cellular protein modification processGO:00064641000.014
localization of cellGO:00516742440.014
determination of left right symmetryGO:00073681790.014
protein secretionGO:000930610.014
negative regulation of developmental processGO:0051093650.014
gland developmentGO:00487321430.014
regulation of cytokine productionGO:000181730.014
regulation of cell developmentGO:00602841000.014
peptide transportGO:001583310.014
cell motilityGO:00488702440.013
regulation of protein targetingGO:190353320.013
positive regulation of muscle cell differentiationGO:005114910.013
sensory neuron axon guidanceGO:009737430.013
vasculature developmentGO:00019442780.013
positive regulation of cellular amine metabolic processGO:003324000.013
sensory perception of chemical stimulusGO:000760630.013
immunoglobulin productionGO:000237710.013
cation homeostasisGO:0055080330.013
protein localizationGO:0008104400.013
synaptic vesicle transportGO:004848910.013
regulation of localizationGO:00328791040.013
regulation of cell matrix adhesionGO:000195210.013
system processGO:00030081850.013
synaptic target recognitionGO:000803910.013
photoreceptor cell fate specificationGO:004370410.013
extrinsic apoptotic signaling pathwayGO:009719130.013
response to nutrientGO:000758430.013
notochord developmentGO:0030903540.013
phosphatidylinositol 3 kinase signalingGO:001406520.013
gtp catabolic processGO:000618420.013
negative regulation of immune responseGO:005077720.013
organelle transport along microtubuleGO:007238410.013
catechol containing compound metabolic processGO:000971220.013
neuron projection developmentGO:00311751800.013
negative regulation of smoothened signaling pathwayGO:004587960.013
proteoglycan biosynthetic processGO:0030166120.013
positive regulation of multicellular organismal processGO:0051240520.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
negative regulation of response to stimulusGO:00485851040.013
regulation of peptidyl tyrosine phosphorylationGO:005073010.013
growthGO:00400071740.013
b cell mediated immunityGO:001972430.013
negative regulation of leukocyte differentiationGO:190210610.013
monocarboxylic acid catabolic processGO:007232930.013
positive regulation of immune effector processGO:000269930.012
hormone transportGO:000991420.012
cell part morphogenesisGO:00329902460.012
retina development in camera type eyeGO:00600411460.012
catecholamine biosynthetic processGO:004242320.012
cellular response to external stimulusGO:007149620.012
digestive tract mesoderm developmentGO:000750210.012
organelle fusionGO:004828430.012
regulation of transmembrane transporter activityGO:002289820.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
positive regulation of epithelial cell differentiationGO:003085820.012
programmed cell deathGO:00125011190.012
response to endogenous stimulusGO:0009719830.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
establishment of protein localization to plasma membraneGO:009000210.012
establishment of synaptic vesicle localizationGO:009748010.012
regulation of filopodium assemblyGO:005148920.012
positive regulation of cytoskeleton organizationGO:005149530.012
regulation of cellular amine metabolic processGO:003323800.012
negative regulation of multicellular organismal processGO:0051241690.012
production of molecular mediator of immune responseGO:000244020.012
protein complex assemblyGO:0006461300.012
response to hexoseGO:000974630.012
membrane organizationGO:0061024210.012
cellular homeostasisGO:0019725260.012
mitochondrion organizationGO:000700540.012
regulation of neurotransmitter secretionGO:004692810.012
smoothened signaling pathway involved in dorsal ventral neural tube patterningGO:006083110.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
head developmentGO:00603223030.011
intracellular mrna localizationGO:000829810.011
regulation of neurotransmitter transportGO:005158810.011
notochord morphogenesisGO:0048570170.011
positive regulation of protein complex assemblyGO:003133420.011
regulation of ion transmembrane transporter activityGO:003241220.011
catechol containing compound biosynthetic processGO:000971320.011
connective tissue developmentGO:0061448990.011
cellular component biogenesisGO:00440851780.011
oocyte maturationGO:000155640.011
nuclear importGO:005117030.011
segmentationGO:0035282970.011
sphingolipid biosynthetic processGO:003014820.011
cellular protein catabolic processGO:004425740.011
positive regulation of synapse assemblyGO:005196510.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.011
cell cycleGO:0007049930.011
lipid catabolic processGO:001604240.011
regulation of gtpase activityGO:004308720.011
positive regulation of bmp signaling pathwayGO:0030513100.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
single organism cellular localizationGO:1902580460.011
immune effector processGO:0002252230.011
establishment of localization in cellGO:0051649770.011
primary neural tube formationGO:001402010.011
multicellular organism reproductionGO:0032504350.011
carbohydrate homeostasisGO:003350010.011
response to vitaminGO:003327330.011
purine nucleoside monophosphate catabolic processGO:000912840.011
nucleotide metabolic processGO:0009117280.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
negative regulation of defense responseGO:003134820.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.011
exocytosisGO:000688710.010
negative regulation of reproductive processGO:200024230.010
astrocyte differentiationGO:004870810.010
protein localization to plasma membraneGO:007265910.010
superoxide metabolic processGO:000680120.010
negative regulation of axon guidanceGO:190266810.010
cell proliferationGO:0008283800.010
membrane lipid biosynthetic processGO:004646720.010
single organism organelle organizationGO:19025891990.010
glucose homeostasisGO:004259310.010
regulation of response to biotic stimulusGO:000283120.010
response to biotic stimulusGO:0009607970.010
cerebellar cortex developmentGO:002169550.010
sequestering of metal ionGO:005123830.010
axonogenesisGO:00074091520.010
response to woundingGO:00096111160.010
photoreceptor cell fate commitmentGO:004655210.010
regulation of extrinsic apoptotic signaling pathwayGO:200123630.010
positive regulation of epithelial cell proliferationGO:005067910.010
guanosine containing compound catabolic processGO:190106920.010
rna 3 end processingGO:003112320.010
central nervous system neuron axonogenesisGO:0021955180.010
periodic partitioningGO:000736510.010
response to bacteriumGO:0009617580.010

enpp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.022
musculoskeletal system diseaseDOID:1700.013
bone diseaseDOID:008000100.011
bone development diseaseDOID:008000600.011
connective tissue diseaseDOID:6500.011