IMP: Integrative Multi-species Prediction

Danio rerio

0 known processes

LOC564867

novel protein similar to LAG1 homolog, ceramide synthase family

Entrez: 564867
Ensembl: ENSDARG00000053583

Process Predictions
Disease Predictions

LOC564867 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
membrane lipid biosynthetic process	GO:0046467	2	0.240
establishment of localization	GO:0051234	244	0.224
aging	GO:0007568	2	0.213
fluid transport	GO:0042044	17	0.130
regulation of metal ion transport	GO:0010959	4	0.114
sphingolipid biosynthetic process	GO:0030148	2	0.113
organic substance biosynthetic process	GO:1901576	289	0.113
ion transport	GO:0006811	114	0.104
tube morphogenesis	GO:0035239	349	0.087
organonitrogen compound metabolic process	GO:1901564	74	0.085
single organism metabolic process	GO:0044710	217	0.082
response to external stimulus	GO:0009605	264	0.082
transmembrane transport	GO:0055085	120	0.081
organic cyclic compound metabolic process	GO:1901360	301	0.079
nitrogen compound metabolic process	GO:0006807	319	0.075
detection of abiotic stimulus	GO:0009582	24	0.074
signal transduction	GO:0007165	455	0.072
positive regulation of cellular component biogenesis	GO:0044089	3	0.068
larval development	GO:0002164	2	0.064
phagocytosis	GO:0006909	3	0.062
single organism biosynthetic process	GO:0044711	71	0.058
anion transport	GO:0006820	38	0.055
cellular component movement	GO:0006928	335	0.055
response to stress	GO:0006950	263	0.051
cellular biosynthetic process	GO:0044249	286	0.050
homeostatic process	GO:0042592	142	0.050
detection of stimulus involved in sensory perception	GO:0050906	21	0.050
morphogenesis of an epithelium	GO:0002009	333	0.049
digestive tract morphogenesis	GO:0048546	231	0.048
cell part morphogenesis	GO:0032990	246	0.048
membrane lipid metabolic process	GO:0006643	10	0.047
regulation of nitrogen compound metabolic process	GO:0051171	251	0.047
ceramide biosynthetic process	GO:0046513	1	0.046
digestive system development	GO:0055123	289	0.045
regulation of macromolecule metabolic process	GO:0060255	317	0.043
organonitrogen compound biosynthetic process	GO:1901566	47	0.042
embryonic organ development	GO:0048568	381	0.040
cellular component morphogenesis	GO:0032989	336	0.040
cellular nitrogen compound metabolic process	GO:0034641	290	0.040
brain development	GO:0007420	293	0.040
cellular aromatic compound metabolic process	GO:0006725	295	0.038
single organism localization	GO:1902578	225	0.038
lipid catabolic process	GO:0016042	4	0.037
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.035
cellular macromolecule metabolic process	GO:0044260	391	0.034
regulation of cellular biosynthetic process	GO:0031326	245	0.034
embryonic skeletal system development	GO:0048706	97	0.033
single organism transport	GO:0044765	206	0.032
locomotion	GO:0040011	313	0.032
regulation of biological quality	GO:0065008	263	0.031
lipid metabolic process	GO:0006629	52	0.031
cellular component assembly	GO:0022607	170	0.030
cellular amine metabolic process	GO:0044106	2	0.030
guanosine containing compound metabolic process	GO:1901068	4	0.030
multicellular organism growth	GO:0035264	4	0.030
mitochondrial transport	GO:0006839	2	0.029
cell surface receptor signaling pathway	GO:0007166	325	0.029
metal ion transport	GO:0030001	58	0.028
chordate embryonic development	GO:0043009	271	0.028
establishment of protein localization to organelle	GO:0072594	4	0.028
transport	GO:0006810	220	0.028
small molecule metabolic process	GO:0044281	77	0.027
regulation of cell shape	GO:0008360	1	0.027
protein metabolic process	GO:0019538	183	0.027
vasculature development	GO:0001944	278	0.026
protein import	GO:0017038	3	0.026
stem cell proliferation	GO:0072089	4	0.026
cellular lipid metabolic process	GO:0044255	36	0.026
biosynthetic process	GO:0009058	294	0.026
gastrulation	GO:0007369	208	0.026
heterocycle biosynthetic process	GO:0018130	215	0.025
cellular response to organic cyclic compound	GO:0071407	38	0.025
regulation of peptidyl tyrosine phosphorylation	GO:0050730	1	0.025
regulation of metabolic process	GO:0019222	359	0.025
cellular respiration	GO:0045333	3	0.025
organic substance transport	GO:0071702	58	0.025
response to chemical	GO:0042221	320	0.025
synaptic growth at neuromuscular junction	GO:0051124	2	0.024
embryonic cranial skeleton morphogenesis	GO:0048701	90	0.024
maintenance of location	GO:0051235	4	0.024
cell aging	GO:0007569	2	0.024
sensory perception of pain	GO:0019233	1	0.024
embryonic organ morphogenesis	GO:0048562	274	0.024
positive regulation of cellular process	GO:0048522	201	0.024
nuclear import	GO:0051170	3	0.024
adult behavior	GO:0030534	2	0.024
nucleobase containing compound metabolic process	GO:0006139	274	0.023
protein targeting to nucleus	GO:0044744	3	0.023
death	GO:0016265	121	0.023
cell migration	GO:0016477	237	0.023
regulation of gene expression	GO:0010468	265	0.023
convergent extension involved in gastrulation	GO:0060027	71	0.023
adherens junction organization	GO:0034332	4	0.023
protein import into nucleus	GO:0006606	3	0.023
regulation of cell communication	GO:0010646	232	0.022
organic hydroxy compound transport	GO:0015850	14	0.022
lipid biosynthetic process	GO:0008610	22	0.022
monovalent inorganic cation transport	GO:0015672	42	0.022
cellular protein catabolic process	GO:0044257	4	0.022
nucleocytoplasmic transport	GO:0006913	4	0.022
eye development	GO:0001654	277	0.022
positive regulation of transport	GO:0051050	2	0.022
ubiquitin dependent protein catabolic process	GO:0006511	3	0.022
positive regulation of biological process	GO:0048518	253	0.022
glucose homeostasis	GO:0042593	1	0.022
regulation of reactive oxygen species metabolic process	GO:2000377	2	0.021
regulation of cytoplasmic transport	GO:1903649	4	0.021
cell motility	GO:0048870	244	0.021
regulation of biosynthetic process	GO:0009889	250	0.021
multicellular organismal response to stress	GO:0033555	2	0.021
system process	GO:0003008	185	0.021
modification dependent protein catabolic process	GO:0019941	3	0.021
localization of cell	GO:0051674	244	0.021
response to wounding	GO:0009611	116	0.020
mitochondrion organization	GO:0007005	4	0.020
protein localization to nucleus	GO:0034504	3	0.020
regulation of synapse assembly	GO:0051963	3	0.020
chemical homeostasis	GO:0048878	49	0.020
cell substrate adhesion	GO:0031589	4	0.020
transcription from rna polymerase ii promoter	GO:0006366	80	0.020
camera type eye morphogenesis	GO:0048593	108	0.020
modification dependent macromolecule catabolic process	GO:0043632	3	0.020
purine ribonucleoside monophosphate catabolic process	GO:0009169	4	0.019
cell morphogenesis	GO:0000902	289	0.019
regulation of blood vessel size	GO:0050880	2	0.019
regulation of rna biosynthetic process	GO:2001141	213	0.019
nuclear transport	GO:0051169	4	0.019
nucleic acid metabolic process	GO:0090304	244	0.019
water transport	GO:0006833	15	0.019
determination of left right symmetry	GO:0007368	179	0.018
guanosine containing compound catabolic process	GO:1901069	2	0.018
regulation of primary metabolic process	GO:0080090	311	0.018
regulation of locomotion	GO:0040012	55	0.018
cellular response to nutrient levels	GO:0031669	2	0.018
blood vessel morphogenesis	GO:0048514	216	0.018
oxoacid metabolic process	GO:0043436	31	0.018
specification of symmetry	GO:0009799	204	0.018
organic acid catabolic process	GO:0016054	3	0.018
regulation of protein polymerization	GO:0032271	2	0.018
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	2	0.018
positive regulation of catabolic process	GO:0009896	4	0.018
neuron differentiation	GO:0030182	353	0.018
determination of bilateral symmetry	GO:0009855	204	0.017
amine metabolic process	GO:0009308	2	0.017
inorganic cation transmembrane transport	GO:0098662	50	0.017
positive regulation of blood circulation	GO:1903524	2	0.017
negative regulation of protein transport	GO:0051224	3	0.017
regulation of tube size	GO:0035150	2	0.017
sensory organ development	GO:0007423	393	0.017
positive regulation of protein complex assembly	GO:0031334	2	0.017
leukocyte proliferation	GO:0070661	1	0.017
epithelial tube morphogenesis	GO:0060562	148	0.017
regulation of multicellular organismal process	GO:0051239	277	0.016
regulation of neural precursor cell proliferation	GO:2000177	3	0.016
hormone transport	GO:0009914	2	0.016
regulation of reproductive process	GO:2000241	4	0.016
heterocycle metabolic process	GO:0046483	290	0.016
cation transport	GO:0006812	81	0.016
digestive tract development	GO:0048565	265	0.016
inner ear development	GO:0048839	126	0.016
angiogenesis	GO:0001525	158	0.016
cellular component biogenesis	GO:0044085	178	0.016
cellular ketone metabolic process	GO:0042180	11	0.016
proteolysis involved in cellular protein catabolic process	GO:0051603	3	0.016
response to carbohydrate	GO:0009743	3	0.016
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.016
regulation of cellular amine metabolic process	GO:0033238	0	0.016
regulation of synaptic growth at neuromuscular junction	GO:0008582	1	0.016
meiotic cell cycle process	GO:1903046	3	0.015
regulation of cellular amino acid metabolic process	GO:0006521	0	0.015
cellular response to organic substance	GO:0071310	105	0.015
response to hexose	GO:0009746	3	0.015
regulation of rna metabolic process	GO:0051252	224	0.015
head development	GO:0060322	303	0.015
organelle organization	GO:0006996	227	0.015
rna metabolic process	GO:0016070	219	0.015
stem cell maintenance	GO:0019827	4	0.015
rna biosynthetic process	GO:0032774	181	0.015
lipid homeostasis	GO:0055088	3	0.015
neurological system process	GO:0050877	62	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	114	0.015
neuron projection morphogenesis	GO:0048812	161	0.015
gtp catabolic process	GO:0006184	2	0.015
embryonic skeletal system morphogenesis	GO:0048704	93	0.015
cellular amino acid metabolic process	GO:0006520	7	0.015
muscle structure development	GO:0061061	196	0.014
regulation of hormone secretion	GO:0046883	2	0.014
multi organism process	GO:0051704	134	0.014
regulation of synapse organization	GO:0050807	3	0.014
regulation of nervous system development	GO:0051960	90	0.014
negative regulation of nucleocytoplasmic transport	GO:0046823	2	0.014
regulation of cellular protein catabolic process	GO:1903362	1	0.014
sensory organ morphogenesis	GO:0090596	200	0.014
regulation of multicellular organism growth	GO:0040014	4	0.014
homeostasis of number of cells	GO:0048872	62	0.014
carboxylic acid metabolic process	GO:0019752	22	0.014
lymphocyte proliferation	GO:0046651	1	0.014
cellular protein metabolic process	GO:0044267	129	0.014
microtubule based movement	GO:0007018	33	0.014
defense response to bacterium	GO:0042742	22	0.014
actin filament polymerization	GO:0030041	2	0.014
protein polymerization	GO:0051258	4	0.013
regulation of ion transmembrane transporter activity	GO:0032412	2	0.013
cellular response to external stimulus	GO:0071496	2	0.013
protein stabilization	GO:0050821	2	0.013
immune system process	GO:0002376	241	0.013
developmental growth	GO:0048589	166	0.013
post embryonic organ development	GO:0048569	4	0.013
regulation of anatomical structure size	GO:0090066	33	0.013
response to monosaccharide	GO:0034284	3	0.013
detection of external stimulus	GO:0009581	24	0.013
regulation of nucleotide catabolic process	GO:0030811	2	0.013
urea transmembrane transport	GO:0071918	9	0.013
lipid storage	GO:0019915	1	0.013
generation of neurons	GO:0048699	385	0.013
meiotic nuclear division	GO:0007126	4	0.013
regulation of macromolecule biosynthetic process	GO:0010556	225	0.013
skeletal system development	GO:0001501	181	0.013
response to biotic stimulus	GO:0009607	97	0.013
regulation of stem cell differentiation	GO:2000736	4	0.013
cellular homeostasis	GO:0019725	26	0.013
negative regulation of intracellular protein transport	GO:0090317	3	0.013
regulation of protein complex assembly	GO:0043254	3	0.013
g protein coupled receptor signaling pathway	GO:0007186	74	0.013
regulation of protein metabolic process	GO:0051246	56	0.013
cytoskeleton organization	GO:0007010	96	0.013
regulation of catalytic activity	GO:0050790	55	0.013
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	2	0.012
renal system development	GO:0072001	94	0.012
hormone secretion	GO:0046879	2	0.012
negative regulation of response to stimulus	GO:0048585	104	0.012
cell projection morphogenesis	GO:0048858	244	0.012
regulation of rho protein signal transduction	GO:0035023	2	0.012
cellular component disassembly	GO:0022411	1	0.012
regulation of anatomical structure morphogenesis	GO:0022603	130	0.012
nucleic acid templated transcription	GO:0097659	181	0.012
nucleobase containing compound biosynthetic process	GO:0034654	205	0.012
regulation of protein catabolic process	GO:0042176	1	0.012
defense response	GO:0006952	47	0.012
transcription dna templated	GO:0006351	181	0.012
smooth muscle contraction	GO:0006939	2	0.012
actin polymerization or depolymerization	GO:0008154	2	0.012
regulation of protein import into nucleus	GO:0042306	2	0.012
positive regulation of cellular amine metabolic process	GO:0033240	0	0.012
extrinsic apoptotic signaling pathway	GO:0097191	3	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.012
muscle contraction	GO:0006936	18	0.012
renal system process	GO:0003014	14	0.012
positive regulation of multicellular organismal process	GO:0051240	52	0.012
proteasomal protein catabolic process	GO:0010498	2	0.012
lateral line system development	GO:0048925	76	0.012
inorganic ion transmembrane transport	GO:0098660	57	0.012
ion transmembrane transport	GO:0034220	91	0.012
negative regulation of protein phosphorylation	GO:0001933	4	0.012
cellular response to hormone stimulus	GO:0032870	39	0.011
regulation of receptor activity	GO:0010469	2	0.011
regulation of transmembrane transporter activity	GO:0022898	2	0.011
negative regulation of protein localization to nucleus	GO:1900181	2	0.011
positive regulation of cytoskeleton organization	GO:0051495	3	0.011
neuron neuron synaptic transmission	GO:0007270	1	0.011
regulation of cellular ketone metabolic process	GO:0010565	7	0.011
fertilization	GO:0009566	3	0.011
interspecies interaction between organisms	GO:0044419	4	0.011
muscle cell differentiation	GO:0042692	139	0.011
renal absorption	GO:0070293	1	0.011
small molecule catabolic process	GO:0044282	3	0.011
regulation of stem cell proliferation	GO:0072091	2	0.011
regulation of protein transport	GO:0051223	3	0.011
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	1	0.011
regulation of signaling	GO:0023051	235	0.011
kidney development	GO:0001822	92	0.011
synaptic vesicle localization	GO:0097479	1	0.011
tissue remodeling	GO:0048771	4	0.011
regulation of transporter activity	GO:0032409	2	0.011
gene expression	GO:0010467	252	0.011
inorganic anion transport	GO:0015698	25	0.011
regulation of cell development	GO:0060284	100	0.011
regulation of cellular metabolic process	GO:0031323	320	0.011
regulation of cell migration	GO:0030334	40	0.011
organic cyclic compound biosynthetic process	GO:1901362	223	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	4	0.011
negative regulation of biological process	GO:0048519	304	0.011
gtp metabolic process	GO:0046039	4	0.011
regulation of microtubule cytoskeleton organization	GO:0070507	3	0.011
regulation of developmental process	GO:0050793	247	0.010
cilium morphogenesis	GO:0060271	85	0.010
water homeostasis	GO:0030104	4	0.010
regulation of signal transduction	GO:0009966	225	0.010
synaptic vesicle transport	GO:0048489	1	0.010
reactive oxygen species metabolic process	GO:0072593	6	0.010
detection of stimulus	GO:0051606	29	0.010
exocytosis	GO:0006887	1	0.010
cell projection organization	GO:0030030	284	0.010
positive regulation of secretion	GO:0051047	1	0.010
regulation of programmed cell death	GO:0043067	101	0.010
regulation of sodium ion transport	GO:0002028	2	0.010
regulation of response to stimulus	GO:0048583	269	0.010
protein modification process	GO:0036211	100	0.010
regulation of extrinsic apoptotic signaling pathway	GO:2001236	3	0.010
reflex	GO:0060004	2	0.010
blood vessel development	GO:0001568	246	0.010
regulation of establishment of protein localization	GO:0070201	4	0.010
retina development in camera type eye	GO:0060041	146	0.010
positive regulation of cytokine production	GO:0001819	2	0.010
macromolecule modification	GO:0043412	111	0.010
positive regulation of cellular catabolic process	GO:0031331	3	0.010
nephron development	GO:0072006	31	0.010
response to glucose	GO:0009749	3	0.010

LOC564867 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.055
nervous system disease	DOID:863	0.019
disease of metabolism	DOID:0014667	0.015
disease of cellular proliferation	DOID:14566	0.010
cancer	DOID:162	0.010

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