Danio rerio

0 known processes

letm1

leucine zipper-EF-hand containing transmembrane protein 1

(Aliases: MGC109969,MGC191626,wu:fc58h01,zgc:109969,wu:fc31h08)

letm1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell communicationGO:00106462320.103
multicellular organism growthGO:003526440.102
larval developmentGO:000216420.098
regulation of signalingGO:00230512350.089
regulation of signal transductionGO:00099662250.083
agingGO:000756820.067
signal transductionGO:00071654550.067
regulation of response to stimulusGO:00485832690.064
negative regulation of protein phosphorylationGO:000193340.063
negative regulation of cellular processGO:00485232830.063
regulation of multicellular organism growthGO:004001440.058
nucleobase containing compound metabolic processGO:00061392740.057
embryonic organ developmentGO:00485683810.055
negative regulation of protein kinase activityGO:000646940.054
regulation of establishment of protein localizationGO:007020140.054
regulation of biosynthetic processGO:00098892500.053
regulation of cellular macromolecule biosynthetic processGO:20001122220.051
aromatic compound biosynthetic processGO:00194382170.049
response to chemicalGO:00422213200.048
cellular macromolecule metabolic processGO:00442603910.048
cell surface receptor signaling pathwayGO:00071663250.047
negative regulation of kinase activityGO:003367340.047
establishment of protein localization to organelleGO:007259440.046
cellular nitrogen compound metabolic processGO:00346412900.046
negative regulation of biological processGO:00485193040.045
nucleobase containing compound biosynthetic processGO:00346542050.045
regulation of rna biosynthetic processGO:20011412130.045
regulation of metabolic processGO:00192223590.045
organelle organizationGO:00069962270.045
regulation of macromolecule metabolic processGO:00602553170.044
transcription dna templatedGO:00063511810.044
regulation of nitrogen compound metabolic processGO:00511712510.043
nitrogen compound metabolic processGO:00068073190.043
heterocycle metabolic processGO:00464832900.042
organic cyclic compound biosynthetic processGO:19013622230.042
nucleic acid templated transcriptionGO:00976591810.042
single organism localizationGO:19025782250.041
nuclear transportGO:005116940.041
biosynthetic processGO:00090582940.040
regulation of cellular metabolic processGO:00313233200.039
transportGO:00068102200.038
nucleocytoplasmic transportGO:000691340.038
positive regulation of biological processGO:00485182530.038
hemopoiesisGO:00300971830.038
protein importGO:001703830.037
regulation of protein transportGO:005122330.037
cellular nitrogen compound biosynthetic processGO:00442712180.037
protein localization to nucleusGO:003450430.037
regulation of transcription dna templatedGO:00063552130.036
immune system developmentGO:00025201910.036
phagocytosisGO:000690930.035
positive regulation of catabolic processGO:000989640.035
regulation of primary metabolic processGO:00800903110.035
cellular amine metabolic processGO:004410620.035
cellular biosynthetic processGO:00442492860.035
cellular macromolecule biosynthetic processGO:00346452240.035
endosomal transportGO:001619720.034
developmental growthGO:00485891660.034
amine metabolic processGO:000930820.034
proteolysis involved in cellular protein catabolic processGO:005160330.034
modification dependent protein catabolic processGO:001994130.034
cytokinesisGO:000091030.034
cellular component morphogenesisGO:00329893360.034
establishment of localizationGO:00512342440.034
regulation of nucleobase containing compound metabolic processGO:00192192500.034
organic substance biosynthetic processGO:19015762890.034
regulation of intracellular protein transportGO:003315730.034
response to uvGO:000941130.034
stem cell proliferationGO:007208940.033
positive regulation of cellular amino acid metabolic processGO:004576400.033
positive regulation of cellular catabolic processGO:003133130.033
single organism nuclear importGO:190259330.033
nucleic acid metabolic processGO:00903042440.033
protein targeting to nucleusGO:004474430.033
carboxylic acid metabolic processGO:0019752220.032
regulation of protein complex assemblyGO:004325430.032
protein import into nucleusGO:000660630.032
negative regulation of protein serine threonine kinase activityGO:007190120.032
single organism metabolic processGO:00447102170.032
transcription from rna polymerase ii promoterGO:0006366800.032
cell part morphogenesisGO:00329902460.031
positive regulation of transportGO:005105020.031
positive regulation of secretionGO:005104710.031
small molecule metabolic processGO:0044281770.031
sensory organ developmentGO:00074233930.031
cellular aromatic compound metabolic processGO:00067252950.031
positive regulation of cellular processGO:00485222010.031
regulation of macromolecule biosynthetic processGO:00105562250.031
regulation of hormone secretionGO:004688320.031
regulation of cytokine productionGO:000181730.030
stem cell maintenanceGO:001982740.030
maintenance of locationGO:005123540.030
positive regulation of secretion by cellGO:190353210.030
response to topologically incorrect proteinGO:003596620.030
ribonucleoside monophosphate catabolic processGO:000915840.030
gtp catabolic processGO:000618420.030
rna biosynthetic processGO:00327741810.030
rna metabolic processGO:00160702190.030
organic acid metabolic processGO:0006082310.030
positive regulation of cell cycleGO:004578730.029
golgi vesicle transportGO:004819330.029
regulation of cellular amino acid metabolic processGO:000652100.029
response to drugGO:004249330.029
guanosine containing compound catabolic processGO:190106920.029
centrosome organizationGO:005129710.029
membrane invaginationGO:001032410.028
regulation of bindingGO:005109830.028
response to stressGO:00069502630.028
regulation of jak stat cascadeGO:004642530.028
purine nucleoside monophosphate catabolic processGO:000912840.028
morphogenesis of an epitheliumGO:00020093330.028
regulation of cellular biosynthetic processGO:00313262450.028
exocytosisGO:000688710.027
locomotionGO:00400113130.027
negative regulation of ras protein signal transductionGO:004658010.027
cellular component movementGO:00069283350.027
organic cyclic compound metabolic processGO:19013603010.027
positive regulation of cellular amine metabolic processGO:003324000.027
positive regulation of protein complex assemblyGO:003133420.026
protein polymerizationGO:005125840.026
guanosine containing compound metabolic processGO:190106840.026
regulation of dendrite developmentGO:005077330.026
regulation of cytoplasmic transportGO:190364940.026
nuclear importGO:005117030.026
cell projection organizationGO:00300302840.026
positive regulation of nitrogen compound metabolic processGO:0051173690.026
negative regulation of cell communicationGO:0010648960.026
immune system processGO:00023762410.026
er to golgi vesicle mediated transportGO:000688810.026
heterocycle biosynthetic processGO:00181302150.026
gtp metabolic processGO:004603940.025
generation of neuronsGO:00486993850.025
cellular amino acid metabolic processGO:000652070.025
neurotransmitter transportGO:000683620.025
regulation of cellular amine metabolic processGO:003323800.025
autophagyGO:000691440.025
central nervous system developmentGO:00074173870.025
actin polymerization or depolymerizationGO:000815420.025
lipid storageGO:001991510.025
extrinsic apoptotic signaling pathwayGO:009719130.024
negative regulation of map kinase activityGO:004340720.024
adherens junction organizationGO:003433240.024
tissue remodelingGO:004877140.024
purine ribonucleoside monophosphate catabolic processGO:000916940.024
regulation of cellular ketone metabolic processGO:001056570.024
oxoacid metabolic processGO:0043436310.024
regulation of cell shapeGO:000836010.024
neuron differentiationGO:00301823530.024
single organism transportGO:00447652060.024
cortical cytoskeleton organizationGO:003086510.024
phosphate containing compound metabolic processGO:00067961080.023
membrane fusionGO:006102520.023
compound eye developmentGO:004874920.023
mitochondrion organizationGO:000700540.023
cell projection morphogenesisGO:00488582440.023
response to carbohydrateGO:000974330.023
response to external stimulusGO:00096052640.023
cell motilityGO:00488702440.023
xenobiotic metabolic processGO:000680540.023
regulation of synaptic plasticityGO:004816710.023
peptidyl serine phosphorylationGO:001810510.023
meiotic nuclear divisionGO:000712640.023
regulation of dendrite morphogenesisGO:004881430.023
macromolecule modificationGO:00434121110.022
peptide transportGO:001583310.022
brain developmentGO:00074202930.022
cell morphogenesisGO:00009022890.022
modification dependent macromolecule catabolic processGO:004363230.022
cellular response to external stimulusGO:007149620.022
long chain fatty acid metabolic processGO:000167610.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
embryonic organ morphogenesisGO:00485622740.022
cellular response to nutrient levelsGO:003166920.022
regulation of protein modification by small protein conjugation or removalGO:190332030.022
ubiquitin dependent protein catabolic processGO:000651130.022
regulation of developmental processGO:00507932470.022
cellular response to lipopolysaccharideGO:007122230.022
cellular protein metabolic processGO:00442671290.021
regulation of protein ubiquitinationGO:003139630.021
intracellular signal transductionGO:0035556850.021
hormone transportGO:000991420.021
regulation of rna metabolic processGO:00512522240.021
digestive tract morphogenesisGO:00485462310.021
hormone secretionGO:004687920.021
cellular response to biotic stimulusGO:007121630.021
somatic muscle developmentGO:000752540.021
negative regulation of signal transductionGO:0009968940.021
cellular ketone metabolic processGO:0042180110.021
synaptic growth at neuromuscular junctionGO:005112420.021
chordate embryonic developmentGO:00430092710.021
cellular response to extracellular stimulusGO:003166820.021
single organism organelle organizationGO:19025891990.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
positive regulation of myeloid cell differentiationGO:004563920.020
atp catabolic processGO:000620040.020
macromolecule biosynthetic processGO:00090592270.020
eye developmentGO:00016542770.020
locomotor rhythmGO:004547530.020
growthGO:00400071740.020
response to other organismGO:0051707970.020
camera type eye developmentGO:00430102220.020
negative regulation of metabolic processGO:0009892860.020
phagocytosis engulfmentGO:000691110.020
negative regulation of cytokine productionGO:000181810.020
regulation of protein targetingGO:190353320.020
cellular component disassemblyGO:002241110.020
cellular protein catabolic processGO:004425740.020
negative regulation of cellular metabolic processGO:0031324770.020
single organism membrane fusionGO:004480120.020
positive regulation of canonical wnt signaling pathwayGO:009026340.020
protein metabolic processGO:00195381830.019
regulation of epithelial cell proliferationGO:005067830.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
response to external biotic stimulusGO:0043207970.019
adult behaviorGO:003053420.019
regulation of nucleotide catabolic processGO:003081120.019
regulation of neurotransmitter transportGO:005158810.019
negative regulation of mapk cascadeGO:004340940.019
regulation of protein import into nucleusGO:004230620.019
negative regulation of response to stimulusGO:00485851040.019
positive regulation of exocytosisGO:004592110.019
nucleic acid transportGO:005065720.019
regulation of erk1 and erk2 cascadeGO:007037240.019
neuron developmentGO:00486662620.019
peptidyl threonine phosphorylationGO:001810710.019
response to monosaccharideGO:003428430.019
positive regulation of cell adhesionGO:004578510.019
system processGO:00030081850.019
cellular response to starvationGO:000926710.019
positive regulation of cellular component biogenesisGO:004408930.019
regulation of nucleoside metabolic processGO:000911820.019
negative regulation of cytoplasmic transportGO:190365020.019
erk1 and erk2 cascadeGO:007037140.019
macromolecular complex disassemblyGO:003298410.018
embryo development ending in birth or egg hatchingGO:00097922710.018
hematopoietic or lymphoid organ developmentGO:00485341910.018
cell cycle g1 s phase transitionGO:004484310.018
cell matrix adhesionGO:000716040.018
rna localizationGO:000640340.018
anterior posterior pattern specificationGO:00099521520.018
digestive tract developmentGO:00485652650.018
regulation of stem cell proliferationGO:007209120.018
regulation of nucleocytoplasmic transportGO:004682220.018
regulation of wound healingGO:006104120.018
regulation of protein localization to nucleusGO:190018020.018
neuron neuron synaptic transmissionGO:000727010.018
localization of cellGO:00516742440.017
neurotransmitter secretionGO:000726920.017
cellular component biogenesisGO:00440851780.017
digestive system developmentGO:00551232890.017
regulation of intracellular signal transductionGO:1902531570.017
stem cell divisionGO:001714510.017
regulation of multicellular organismal processGO:00512392770.017
gastrulationGO:00073692080.017
regulation of purine nucleotide catabolic processGO:003312120.017
nucleoside monophosphate catabolic processGO:000912540.017
rna transportGO:005065820.017
protein acetylationGO:000647320.017
vasculature developmentGO:00019442780.017
internal peptidyl lysine acetylationGO:001839320.017
actin filament polymerizationGO:003004120.017
negative regulation of protein complex assemblyGO:003133310.017
cellular response to molecule of bacterial originGO:007121930.017
b cell activationGO:004211320.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
regulation of protein polymerizationGO:003227120.017
positive regulation of notch signaling pathwayGO:004574730.017
response to biotic stimulusGO:0009607970.017
response to nutrientGO:000758430.016
regulation of biological qualityGO:00650082630.016
regulation of synapse organizationGO:005080730.016
regulation of response to nutrient levelsGO:003210710.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
gene expressionGO:00104672520.016
meiotic cell cycle processGO:190304630.016
peptidyl serine modificationGO:001820920.016
positive regulation of immune effector processGO:000269930.016
cell substrate adhesionGO:003158940.016
cellular response to chemical stimulusGO:00708871570.016
somite developmentGO:0061053960.016
small gtpase mediated signal transductionGO:000726480.016
establishment of rna localizationGO:005123630.016
positive regulation of nucleoside metabolic processGO:004597910.016
head developmentGO:00603223030.016
organelle fusionGO:004828430.016
negative regulation of signalingGO:0023057960.016
fatty acid biosynthetic processGO:000663340.016
protein acylationGO:004354330.016
regulation of synapse assemblyGO:005196330.016
cellular carbohydrate metabolic processGO:004426240.016
regulation of gene expressionGO:00104682650.016
positive regulation of striated muscle tissue developmentGO:004584410.016
response to unfolded proteinGO:000698620.016
cellular component assembly involved in morphogenesisGO:00109271070.016
internal protein amino acid acetylationGO:000647520.016
protein complex disassemblyGO:004324110.016
positive regulation of nucleotide catabolic processGO:003081310.016
endoplasmic reticulum unfolded protein responseGO:003096820.015
microtubule organizing center organizationGO:003102310.015
cortical actin cytoskeleton organizationGO:003086610.015
tube closureGO:006060610.015
regulation of response to extracellular stimulusGO:003210410.015
protein modification processGO:00362111000.015
negative regulation of macromolecule metabolic processGO:0010605760.015
response to hexoseGO:000974630.015
establishment of protein localization to plasma membraneGO:009000210.015
positive regulation of gtpase activityGO:004354710.015
regulation of stem cell differentiationGO:200073640.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
positive regulation of cellular metabolic processGO:0031325940.015
positive regulation of epithelial cell migrationGO:001063420.015
tube morphogenesisGO:00352393490.015
somatic stem cell maintenanceGO:003501910.015
regulation of metal ion transportGO:001095940.015
neuron projection morphogenesisGO:00488121610.015
defense response to other organismGO:0098542330.015
sleepGO:003043110.015
organonitrogen compound metabolic processGO:1901564740.015
cognitionGO:005089010.015
peptidyl lysine acetylationGO:001839420.015
single fertilizationGO:000733830.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
angiogenesisGO:00015251580.015
proteasomal protein catabolic processGO:001049820.015
cellular localizationGO:0051641970.015
protein dephosphorylationGO:000647030.015
cytoskeleton organizationGO:0007010960.015
blood vessel developmentGO:00015682460.015
regulation of cell activationGO:005086510.015
carbohydrate homeostasisGO:003350010.015
chemosensory behaviorGO:000763510.015
vacuolar transportGO:000703420.015
synaptic vesicle localizationGO:009747910.014
glucose homeostasisGO:004259310.014
mitotic dna integrity checkpointGO:004477440.014
regulation of exocytosisGO:001715710.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
wnt signaling pathwayGO:0016055800.014
regulation of cell substrate adhesionGO:001081010.014
nucleobase containing compound transportGO:001593120.014
organic acid catabolic processGO:001605430.014
axon developmentGO:00615641660.014
cellular response to unfolded proteinGO:003462020.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
cell proliferationGO:0008283800.014
skeletal system developmentGO:00015011810.014
neuroblast proliferationGO:000740520.014
female sex differentiationGO:004666040.014
establishment of localization in cellGO:0051649770.014
regulation of protein catabolic processGO:004217610.014
cellular response to topologically incorrect proteinGO:003596720.014
secondary metabolic processGO:001974830.014
regulation of multicellular organismal developmentGO:20000262230.014
positive regulation of protein polymerizationGO:003227320.014
negative regulation of catabolic processGO:000989530.014
maternal determination of anterior posterior axis embryoGO:000835840.014
mesenchymal cell differentiationGO:0048762870.014
regulation of gtp catabolic processGO:003312420.014
response to glucoseGO:000974930.014
establishment of protein localization to vacuoleGO:007266610.014
inner ear developmentGO:00488391260.014
negative regulation of tor signalingGO:003200720.014
protein homooligomerizationGO:005126030.014
positive regulation of cell activationGO:005086710.014
regulation of apoptotic processGO:0042981980.014
cellular component assemblyGO:00226071700.014
protein localization to plasma membraneGO:007265910.014
lipid catabolic processGO:001604240.014
positive regulation of gtp catabolic processGO:003312610.013
protein complex localizationGO:003150310.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
negative regulation of stem cell differentiationGO:200073720.013
g1 s transition of mitotic cell cycleGO:000008210.013
cellular protein modification processGO:00064641000.013
mitochondrial transportGO:000683920.013
negative regulation of intracellular protein transportGO:009031730.013
cell migrationGO:00164772370.013
nuclear exportGO:005116810.013
positive regulation of macromolecule metabolic processGO:0010604930.013
negative regulation of intracellular transportGO:003238730.013
ras protein signal transductionGO:000726570.013
regulation of localizationGO:00328791040.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
positive regulation of metabolic processGO:00098931080.013
neuron projection developmentGO:00311751800.013
response to bacteriumGO:0009617580.013
mitotic dna damage checkpointGO:004477340.013
negative regulation of epithelial cell proliferationGO:005068010.013
cellular lipid catabolic processGO:004424230.013
regulation of blood pressureGO:000821710.013
response to corticosteroidGO:003196010.013
regulation of gtpase activityGO:004308720.013
stem cell developmentGO:0048864820.013
regulation of programmed cell deathGO:00430671010.013
regulation of neurotransmitter secretionGO:004692810.013
actin cytoskeleton organizationGO:0030036630.013
response to abiotic stimulusGO:00096281220.013
regulation of ion transmembrane transporter activityGO:003241220.013
peptidyl threonine modificationGO:001821010.013
sensory organ morphogenesisGO:00905962000.013
cytoskeleton dependent cytokinesisGO:006164030.013
muscle structure developmentGO:00610611960.013
positive regulation of dna metabolic processGO:005105410.013
regulation of reproductive processGO:200024140.012
establishment of pigment granule localizationGO:0051905220.012
er nucleus signaling pathwayGO:000698420.012
homeostatic processGO:00425921420.012
mesenchyme developmentGO:00604851270.012
centrosome duplicationGO:005129810.012
germ line stem cell maintenanceGO:003071820.012
cell cycleGO:0007049930.012
multicellular organismal response to stressGO:003355520.012
regulation of carbohydrate metabolic processGO:000610940.012
cytokinetic processGO:003250620.012
regulation of transmembrane transporter activityGO:002289820.012
negative regulation of synapse assemblyGO:005196420.012
centrosome cycleGO:000709810.012
i kappab kinase nf kappab signalingGO:000724940.012
fertilizationGO:000956630.012
response to woundingGO:00096111160.012
melanosome transportGO:0032402190.012
response to glucocorticoidGO:005138410.012
endocrine processGO:005088620.012
neurological system processGO:0050877620.012
regulation of reactive oxygen species metabolic processGO:200037720.012
actin filament based movementGO:003004810.012
regulation of protein localization to plasma membraneGO:190307610.012
dna templated transcription elongationGO:000635430.012
regulation of protein depolymerizationGO:190187910.012
organic substance transportGO:0071702580.012
spermatid differentiationGO:004851520.012
regulation of cellular component organizationGO:0051128860.012
positive regulation of cell communicationGO:0010647560.012
negative regulation of protein transportGO:005122430.012
negative regulation of cellular catabolic processGO:003133030.012
development of primary female sexual characteristicsGO:004654540.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
positive regulation of signal transductionGO:0009967560.012
production of molecular mediator of immune responseGO:000244020.012
localization within membraneGO:005166810.012
negative regulation of defense responseGO:003134820.012
membrane lipid biosynthetic processGO:004646720.012
forebrain cell migrationGO:002188510.012
cellular response to radiationGO:007147840.012
somitogenesisGO:0001756870.012
stem cell differentiationGO:00488631170.012
rna export from nucleusGO:000640510.011
regulation of autophagyGO:001050630.011
alcohol biosynthetic processGO:004616520.011
eye morphogenesisGO:00485921440.011
phosphorylationGO:0016310690.011
regulation of protein complex disassemblyGO:004324410.011
positive regulation of rna metabolic processGO:0051254590.011
primary neural tube formationGO:001402010.011
pigment granule transportGO:0051904190.011
positive regulation of stress activated mapk cascadeGO:003287430.011
negative regulation of immune responseGO:005077720.011
positive regulation of cytoskeleton organizationGO:005149530.011
cellular transition metal ion homeostasisGO:004691630.011
regulation of neural precursor cell proliferationGO:200017730.011
positive regulation of signalingGO:0023056560.011
segmentationGO:0035282970.011
regulation of microtubule cytoskeleton organizationGO:007050730.011
establishment of melanosome localizationGO:0032401190.011
blood vessel morphogenesisGO:00485142160.011
regulation of transporter activityGO:003240920.011
defense response to fungusGO:005083220.011
positive regulation of rna biosynthetic processGO:1902680570.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
regulation of establishment of protein localization to plasma membraneGO:009000310.011
convergent extensionGO:00600261180.011
meiosis iGO:000712710.011
regulation of organ growthGO:004662030.011
negative regulation of small gtpase mediated signal transductionGO:005105810.011
neural crest cell differentiationGO:0014033720.011
striated muscle cell differentiationGO:00511461290.011
cellular response to oxygen levelsGO:007145310.011
negative regulation of protein import into nucleusGO:004230820.011
mesenchymal cell developmentGO:0014031780.011
alpha amino acid metabolic processGO:190160530.011
muscle cell differentiationGO:00426921390.011
histone h4 k20 methylationGO:003477020.011
positive regulation of lymphocyte mediated immunityGO:000270810.011
regulation of cell cycleGO:0051726520.011

letm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.024
organ system cancerDOID:005068600.024
disease of cellular proliferationDOID:1456600.024
disease of metabolismDOID:001466700.020
inherited metabolic disorderDOID:65500.020
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.014
musculoskeletal system diseaseDOID:1700.012
sensory system diseaseDOID:005015500.011
eye and adnexa diseaseDOID:149200.011