Danio rerio

44 known processes

psmd6

proteasome (prosome, macropain) 26S subunit, non-ATPase, 6

(Aliases: MGC56471,zgc:56471)

psmd6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ubiquitin dependent protein catabolic processGO:000651130.974
modification dependent macromolecule catabolic processGO:004363230.967
modification dependent protein catabolic processGO:001994130.963
cellular protein catabolic processGO:004425740.956
larval developmentGO:000216420.941
Worm
protein metabolic processGO:00195381830.894
proteolysis involved in cellular protein catabolic processGO:005160330.881
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.873
proteasomal protein catabolic processGO:001049820.827
agingGO:000756820.770
Worm
embryo development ending in birth or egg hatchingGO:00097922710.742
Worm
cellular macromolecule metabolic processGO:00442603910.734
regulation of macromolecule metabolic processGO:00602553170.713
gene expressionGO:00104672520.623
regulation of metabolic processGO:00192223590.597
cellular macromolecule biosynthetic processGO:00346452240.555
nucleic acid metabolic processGO:00903042440.552
regulation of cellular metabolic processGO:00313233200.517
cellular protein metabolic processGO:00442671290.503
cellular macromolecule catabolic processGO:0044265120.477
macromolecule biosynthetic processGO:00090592270.459
positive regulation of cellular processGO:00485222010.410
regulation of biosynthetic processGO:00098892500.407
regulation of primary metabolic processGO:00800903110.378
negative regulation of biological processGO:00485193040.331
regulation of gene expressionGO:00104682650.318
biosynthetic processGO:00090582940.308
locomotionGO:00400113130.283
macromolecule catabolic processGO:0009057150.281
regulation of protein catabolic processGO:004217610.278
regulation of transcription dna templatedGO:00063552130.275
positive regulation of biological processGO:00485182530.275
response to stressGO:00069502630.263
nucleobase containing compound biosynthetic processGO:00346542050.259
single organism organelle organizationGO:19025891990.258
cellular component assemblyGO:00226071700.255
lateral inhibitionGO:004633110.253
meiotic nuclear divisionGO:000712640.247
regulation of protein complex assemblyGO:004325430.232
cellular component biogenesisGO:00440851780.224
organelle organizationGO:00069962270.223
regulation of macromolecule biosynthetic processGO:00105562250.207
cellular nitrogen compound metabolic processGO:00346412900.202
gastrulationGO:00073692080.201
rna biosynthetic processGO:00327741810.201
nucleobase containing compound metabolic processGO:00061392740.197
cellular response to dna damage stimulusGO:0006974240.193
nucleic acid templated transcriptionGO:00976591810.191
regionalizationGO:00030022740.188
organic cyclic compound metabolic processGO:19013603010.182
positive regulation of cellular metabolic processGO:0031325940.182
positive regulation of cellular component biogenesisGO:004408930.182
regulation of protein metabolic processGO:0051246560.181
regulation of cellular macromolecule biosynthetic processGO:20001122220.178
digestive tract developmentGO:00485652650.171
nitrogen compound metabolic processGO:00068073190.168
regulation of cellular biosynthetic processGO:00313262450.165
aromatic compound biosynthetic processGO:00194382170.160
proteolysisGO:0006508380.158
cellular response to stressGO:0033554620.156
rna metabolic processGO:00160702190.155
regulation of nucleobase containing compound metabolic processGO:00192192500.154
regulation of nitrogen compound metabolic processGO:00511712510.146
reproductionGO:0000003400.144
Worm
positive regulation of biosynthetic processGO:0009891680.143
single organism localizationGO:19025782250.135
chordate embryonic developmentGO:00430092710.133
response to chemicalGO:00422213200.132
organic substance catabolic processGO:1901575280.130
cellular nitrogen compound biosynthetic processGO:00442712180.127
regulation of nucleic acid templated transcriptionGO:19035062130.124
protein catabolic processGO:003016370.124
regulation of response to stimulusGO:00485832690.122
negative regulation of cellular processGO:00485232830.121
catabolic processGO:0009056320.119
cell fate commitmentGO:0045165990.118
heterocycle biosynthetic processGO:00181302150.117
positive regulation of catabolic processGO:000989640.117
reproductive processGO:0022414400.113
meiotic cell cycle processGO:190304630.113
positive regulation of cellular biosynthetic processGO:0031328680.107
heterocycle metabolic processGO:00464832900.105
ribonucleoside monophosphate catabolic processGO:000915840.105
purine nucleoside monophosphate catabolic processGO:000912840.102
transcription dna templatedGO:00063511810.101
transcription from rna polymerase ii promoterGO:0006366800.098
cellular catabolic processGO:0044248270.097
organic substance biosynthetic processGO:19015762890.095
regulation of cellular component organizationGO:0051128860.093
positive regulation of gene expressionGO:0010628710.092
homeostatic processGO:00425921420.091
positive regulation of rna biosynthetic processGO:1902680570.088
macromolecule modificationGO:00434121110.086
protein complex assemblyGO:0006461300.085
positive regulation of nitrogen compound metabolic processGO:0051173690.084
cellular protein modification processGO:00064641000.083
signal transductionGO:00071654550.082
single organism reproductive processGO:0044702400.082
mitotic cell cycleGO:0000278640.081
nucleoside monophosphate catabolic processGO:000912540.080
dna templated transcription initiationGO:000635210.079
rrna catabolic processGO:001607510.079
cellular response to nutrient levelsGO:003166920.078
regulation of rna biosynthetic processGO:20011412130.077
atp catabolic processGO:000620040.077
regulation of rna metabolic processGO:00512522240.076
transportGO:00068102200.076
chromosome organizationGO:0051276310.076
regulation of meiotic cell cycleGO:005144510.075
purine ribonucleoside monophosphate catabolic processGO:000916940.074
organic cyclic compound biosynthetic processGO:19013622230.074
regulation of cell communicationGO:00106462320.073
embryonic organ developmentGO:00485683810.073
embryonic skeletal system morphogenesisGO:0048704930.072
cellular biosynthetic processGO:00442492860.072
positive regulation of protein complex assemblyGO:003133420.072
single organism transportGO:00447652060.072
regulation of molecular functionGO:0065009700.071
meiosis iiGO:000713510.070
mitotic g2 dna damage checkpointGO:000709530.068
protein modification processGO:00362111000.068
cellular protein complex assemblyGO:0043623190.067
chemotaxisGO:00069351040.066
regulation of proteolysisGO:0030162240.066
regulation of transcription from rna polymerase ii promoterGO:00063571140.066
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.066
positive regulation of nucleobase containing compound metabolic processGO:0045935690.066
pole plasm assemblyGO:000731540.065
establishment of localizationGO:00512342440.065
macromolecular complex subunit organizationGO:0043933740.063
protein complex subunit organizationGO:0071822460.061
regulation of multicellular organismal processGO:00512392770.061
cellular macromolecular complex assemblyGO:0034622240.061
positive regulation of transcription dna templatedGO:0045893570.060
response to external stimulusGO:00096052640.059
negative regulation of macromolecule metabolic processGO:0010605760.059
meiosis iGO:000712710.059
positive regulation of cellular catabolic processGO:003133130.058
fertilizationGO:000956630.057
autophagyGO:000691440.057
positive regulation of metabolic processGO:00098931080.057
cytoskeleton organizationGO:0007010960.056
regulation of apoptotic processGO:0042981980.056
cell cycleGO:0007049930.056
negative regulation of synapse assemblyGO:005196420.056
mitotic dna integrity checkpointGO:004477440.055
negative regulation of gene expressionGO:0010629650.055
cell projection morphogenesisGO:00488582440.054
cellular response to external stimulusGO:007149620.053
negative regulation of metabolic processGO:0009892860.053
regulation of synaptic growth at neuromuscular junctionGO:000858210.053
cellular aromatic compound metabolic processGO:00067252950.052
defense responseGO:0006952470.052
phosphorus metabolic processGO:00067931090.052
regulation of signal transductionGO:00099662250.052
cell projection organizationGO:00300302840.052
single fertilizationGO:000733830.052
mitotic cell cycle processGO:1903047480.052
response to virusGO:0009615210.051
cell migrationGO:00164772370.050
regulation of signalingGO:00230512350.049
embryonic cranial skeleton morphogenesisGO:0048701900.048
regulation of cellular protein metabolic processGO:0032268520.048
anterior posterior pattern specificationGO:00099521520.048
positive regulation of nucleic acid templated transcriptionGO:1903508570.046
meiotic chromosome segregationGO:004513230.046
developmental process involved in reproductionGO:0003006270.046
regulation of synapse organizationGO:005080730.045
regulation of phosphorus metabolic processGO:0051174430.045
cell deathGO:00082191210.044
Worm
cognitionGO:005089010.044
blood vessel developmentGO:00015682460.044
neuron differentiationGO:00301823530.043
programmed cell deathGO:00125011190.043
Worm
meiotic spindle organizationGO:000021210.043
brain developmentGO:00074202930.042
mitotic sister chromatid segregationGO:000007060.042
regulation of biological qualityGO:00650082630.042
negative regulation of cellular metabolic processGO:0031324770.042
protein modification by small protein removalGO:007064610.041
cellular component morphogenesisGO:00329893360.041
neuron neuron synaptic transmissionGO:000727010.040
positive regulation of macromolecule metabolic processGO:0010604930.040
protein dephosphorylationGO:000647030.039
stem cell divisionGO:001714510.039
generation of neuronsGO:00486993850.039
cellular localizationGO:0051641970.039
mitochondrion organizationGO:000700540.038
oocyte anterior posterior axis specificationGO:000731440.038
regulation of chromosome segregationGO:005198310.037
sister chromatid segregationGO:000081960.037
regulation of synapse assemblyGO:005196330.037
organonitrogen compound metabolic processGO:1901564740.037
protein stabilizationGO:005082120.036
retina development in camera type eyeGO:00600411460.036
sexual reproductionGO:0019953360.035
cell cell signalingGO:0007267520.034
macromolecule localizationGO:0033036540.034
regulation of protein modification by small protein conjugation or removalGO:190332030.034
digestive system developmentGO:00551232890.033
ncrna catabolic processGO:003466110.033
regulation of cellular protein catabolic processGO:190336210.033
positive regulation of cell cycleGO:004578730.033
positive regulation of macromolecule biosynthetic processGO:0010557590.033
cellular response to extracellular stimulusGO:003166820.033
g2 dna damage checkpointGO:003157230.033
positive regulation of protein metabolic processGO:0051247230.032
positive regulation of molecular functionGO:0044093330.032
regulation of cellular amino acid metabolic processGO:000652100.032
negative regulation of chromosome organizationGO:200125110.032
phosphate containing compound metabolic processGO:00067961080.032
regulation of phosphate metabolic processGO:0019220430.032
regulation of cell cycleGO:0051726520.031
embryonic skeletal system developmentGO:0048706970.031
chemical homeostasisGO:0048878490.031
apoptotic processGO:00069151160.031
Worm
positive regulation of rna metabolic processGO:0051254590.030
segmentationGO:0035282970.030
macromolecular complex assemblyGO:0065003350.030
intracellular signal transductionGO:0035556850.030
stem cell differentiationGO:00488631170.030
mitotic g2 m transition checkpointGO:004481830.030
regulation of cellular amine metabolic processGO:003323800.030
small molecule metabolic processGO:0044281770.029
organelle assemblyGO:00709251100.029
erk1 and erk2 cascadeGO:007037140.029
golgi vesicle transportGO:004819330.029
chromosome organization involved in meiosisGO:007019210.029
regulation of bindingGO:005109830.029
response to other organismGO:0051707970.029
regulation of developmental processGO:00507932470.028
negative regulation of nuclear divisionGO:005178430.028
regulation of catalytic activityGO:0050790550.028
positive regulation of erk1 and erk2 cascadeGO:007037420.028
regulation of response to stressGO:0080134360.027
response to biotic stimulusGO:0009607970.026
negative regulation of response to stimulusGO:00485851040.026
multicellular organism growthGO:003526440.026
regulation of reproductive processGO:200024140.026
cell motilityGO:00488702440.025
cell morphogenesis involved in differentiationGO:00009041950.025
cellular response to chemical stimulusGO:00708871570.025
amine metabolic processGO:000930820.025
cellular amine metabolic processGO:004410620.025
multicellular organismal reproductive processGO:0048609350.025
skeletal system developmentGO:00015011810.024
establishment of protein localization to organelleGO:007259440.024
chromosome segregationGO:0007059120.024
positive regulation of cellular protein metabolic processGO:0032270220.024
neuron projection morphogenesisGO:00488121610.024
organelle fissionGO:0048285230.024
tube morphogenesisGO:00352393490.024
positive regulation of secretionGO:005104710.024
regulation of multicellular organismal developmentGO:20000262230.023
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.023
establishment of organelle localizationGO:0051656450.023
regulation of cell deathGO:00109411030.023
actin cytoskeleton organizationGO:0030036630.023
cell cycle processGO:0022402530.023
cell morphogenesisGO:00009022890.023
oocyte developmentGO:0048599140.023
spindle assembly involved in mitosisGO:009030710.023
cellular amino acid metabolic processGO:000652070.022
embryonic pattern specificationGO:0009880440.022
establishment of localization in cellGO:0051649770.022
cell divisionGO:0051301200.022
synaptic growth at neuromuscular junctionGO:005112420.022
regulation of protein ubiquitinationGO:003139630.022
vasculature developmentGO:00019442780.022
negative regulation of cell communicationGO:0010648960.022
negative regulation of cell deathGO:0060548600.022
protein complex biogenesisGO:0070271300.022
cell surface receptor signaling pathwayGO:00071663250.022
deathGO:00162651210.021
Worm
negative regulation of mitosisGO:004583930.021
small gtpase mediated signal transductionGO:000726480.021
stem cell proliferationGO:007208940.021
negative regulation of signalingGO:0023057960.021
immune system processGO:00023762410.020
cytoplasm organizationGO:000702840.020
membrane fusionGO:006102520.020
embryonic organ morphogenesisGO:00485622740.020
response to external biotic stimulusGO:0043207970.020
female sex differentiationGO:004666040.020
cellular response to starvationGO:000926710.019
regulation of nucleoside metabolic processGO:000911820.019
gamete generationGO:0007276330.019
actin filament based processGO:0030029640.019
heart developmentGO:00075073130.019
membrane invaginationGO:001032410.019
regulation of erk1 and erk2 cascadeGO:007037240.019
camera type eye developmentGO:00430102220.019
growthGO:00400071740.019
nucleobase containing small molecule metabolic processGO:0055086320.019
single organism metabolic processGO:00447102170.018
regulation of cytokine productionGO:000181730.018
regulation of response to external stimulusGO:0032101310.018
cellular amide metabolic processGO:004360340.018
dna metabolic processGO:0006259270.018
centrosome organizationGO:005129710.018
regulation of cellular component biogenesisGO:0044087120.018
maintenance of locationGO:005123540.018
spindle assemblyGO:005122520.017
mitotic dna damage checkpointGO:004477340.017
cellular component movementGO:00069283350.017
regulation of establishment of protein localizationGO:007020140.017
axonogenesisGO:00074091520.017
multi organism processGO:00517041340.017
angiogenesisGO:00015251580.017
chromatin modificationGO:0016568210.017
positive regulation of secretion by cellGO:190353210.017
positive regulation of catalytic activityGO:0043085250.017
negative regulation of multicellular organismal processGO:0051241690.016
post embryonic developmentGO:000979170.016
Worm
organic substance transportGO:0071702580.016
regulation of sequence specific dna binding transcription factor activityGO:005109090.016
protein localizationGO:0008104400.016
system processGO:00030081850.016
blood vessel morphogenesisGO:00485142160.016
phagocytosisGO:000690930.016
digestive tract morphogenesisGO:00485462310.016
positive regulation of histone modificationGO:003105810.016
protein acylationGO:004354330.016
regulation of cell differentiationGO:00455951420.016
localization of cellGO:00516742440.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.015
cellular component disassemblyGO:002241110.015
transcription elongation from rna polymerase ii promoterGO:000636830.015
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.015
negative regulation of cellular biosynthetic processGO:0031327550.015
regulation of programmed cell deathGO:00430671010.015
neuron developmentGO:00486662620.015
negative regulation of proteolysisGO:0045861100.015
nuclear divisionGO:0000280230.015
double strand break repairGO:000630230.015
protein localization to nucleusGO:003450430.015
maternal determination of anterior posterior axis embryoGO:000835840.015
regulation of inflammatory responseGO:005072720.015
carboxylic acid metabolic processGO:0019752220.015
pronuclear migrationGO:003504610.015
negative regulation of defense responseGO:003134820.015
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.015
regulation of synaptic plasticityGO:004816710.015
morphogenesis of an epitheliumGO:00020093330.015
regulation of mitotic cell cycleGO:0007346250.015
macroautophagyGO:001623610.015
heterocycle catabolic processGO:0046700150.015
regulation of purine nucleotide catabolic processGO:003312120.014
protein secretionGO:000930610.014
ameboidal type cell migrationGO:00016671430.014
regulation of cellular ketone metabolic processGO:001056570.014
negative regulation of neural precursor cell proliferationGO:200017810.014
cellular carbohydrate metabolic processGO:004426240.014
negative regulation of protein phosphorylationGO:000193340.014
sensory organ morphogenesisGO:00905962000.014
regulation of cytoplasmic transportGO:190364940.014
nuclear transportGO:005116940.014
dna repairGO:000628160.014
cellular response to organic substanceGO:00713101050.014
negative regulation of transcription dna templatedGO:0045892450.014
neuroblast proliferationGO:000740520.014
protein complex disassemblyGO:004324110.014
cellular transition metal ion homeostasisGO:004691630.014
protein complex localizationGO:003150310.014
anterior posterior axis specificationGO:0009948200.014
sleepGO:003043110.013
mesenchymal cell differentiationGO:0048762870.013
regulation of cell developmentGO:00602841000.013
dna biosynthetic processGO:007189730.013
mitotic nuclear divisionGO:0007067180.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
response to endogenous stimulusGO:0009719830.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
dna templated transcription elongationGO:000635430.013
regulation of gene expression epigeneticGO:0040029110.013
regulation of organelle organizationGO:0033043290.013
lens development in camera type eyeGO:0002088220.013
negative regulation of apoptotic processGO:0043066550.013
gland developmentGO:00487321430.013
negative regulation of macromolecule biosynthetic processGO:0010558480.013
positive regulation of chromosome organizationGO:200125210.013
aromatic compound catabolic processGO:0019439150.013
regulation of nuclear divisionGO:005178390.013
cell death in response to oxidative stressGO:003647320.013
response to monosaccharideGO:003428430.013
sensory organ developmentGO:00074233930.013
positive regulation of nucleoside metabolic processGO:004597910.013
cell cycle phase transitionGO:004477090.012
multicellular organism reproductionGO:0032504350.012
axonal defasciculationGO:000741420.012
eye morphogenesisGO:00485921440.012
regulation of protein modification processGO:0031399290.012
negative regulation of cellular protein metabolic processGO:0032269160.012
negative regulation of nervous system developmentGO:0051961220.012
eye developmentGO:00016542770.012
epidermal cell fate specificationGO:000995740.012
regulation of locomotionGO:0040012550.012
response to topologically incorrect proteinGO:003596620.012
adult behaviorGO:003053420.012
negative regulation of biosynthetic processGO:0009890550.012
iron ion homeostasisGO:005507240.012
double strand break repair via homologous recombinationGO:000072410.012
regulation of cell cycle processGO:0010564200.012
purine nucleotide metabolic processGO:0006163270.012
hatchingGO:003518840.012
specification of symmetryGO:00097992040.012
negative regulation of translationGO:001714810.011
phosphorylationGO:0016310690.011
macromolecular complex disassemblyGO:003298410.011
regulation of immune system processGO:0002682340.011
peptidyl serine modificationGO:001820920.011
protein importGO:001703830.011
regulation of response to oxidative stressGO:190288220.011
single organism catabolic processGO:0044712130.011
organism emergence from protective structureGO:007168440.011
microtubule based processGO:0007017600.011
regulation of phosphorylationGO:0042325260.011
oxoacid metabolic processGO:0043436310.011
negative regulation of signal transductionGO:0009968940.011
regulation of intracellular signal transductionGO:1902531570.011
microtubule cytoskeleton organization involved in mitosisGO:190285010.011
response to nicotineGO:003509420.011
peptidyl serine phosphorylationGO:001810510.011
cellular ketone metabolic processGO:0042180110.011
protein targeting to nucleusGO:004474430.011
regulation of mitosisGO:000708890.011
mesenchymal cell developmentGO:0014031780.010
cell part morphogenesisGO:00329902460.010
regulation of nucleotide catabolic processGO:003081120.010
developmental growthGO:00485891660.010
regulation of dna templated transcription elongationGO:003278430.010
microtubule organizing center organizationGO:003102310.010
organelle localizationGO:0051640490.010
skeletal system morphogenesisGO:00487051020.010
negative regulation of catabolic processGO:000989530.010
eye photoreceptor cell differentiationGO:0001754450.010
positive regulation of transportGO:005105020.010
establishment or maintenance of cell polarityGO:0007163290.010
protein import into nucleusGO:000660630.010
cell fate specificationGO:0001708680.010

psmd6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
neurodegenerative diseaseDOID:128900.032
nervous system diseaseDOID:86300.032
motor neuron diseaseDOID:23100.032
central nervous system diseaseDOID:33100.032
amyotrophic lateral sclerosisDOID:33200.032
organ system cancerDOID:005068600.011
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011