Danio rerio

0 known processes

brap

BRCA1 associated protein

(Aliases: zgc:92894)

brap biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:000756820.171
organelle organizationGO:00069962270.121
nucleobase containing compound metabolic processGO:00061392740.115
larval developmentGO:000216420.110
histone demethylationGO:001657720.108
response to chemicalGO:00422213200.101
signal transductionGO:00071654550.093
Human
negative regulation of biological processGO:00485193040.091
Human
single organism organelle organizationGO:19025891990.083
rna metabolic processGO:00160702190.080
organic cyclic compound metabolic processGO:19013603010.074
macromolecule biosynthetic processGO:00090592270.073
multicellular organism growthGO:003526440.072
regulation of nucleobase containing compound metabolic processGO:00192192500.072
cellular biosynthetic processGO:00442492860.070
cellular macromolecule metabolic processGO:00442603910.067
Human
organelle assemblyGO:00709251100.067
phagocytosisGO:000690930.066
biosynthetic processGO:00090582940.066
autophagyGO:000691440.065
positive regulation of biological processGO:00485182530.065
nucleic acid metabolic processGO:00903042440.061
maintenance of locationGO:005123540.059
positive regulation of cellular catabolic processGO:003133130.059
regulation of nitrogen compound metabolic processGO:00511712510.059
establishment of protein localization to organelleGO:007259440.059
regulation of biosynthetic processGO:00098892500.058
protein metabolic processGO:00195381830.058
Human
regulation of macromolecule metabolic processGO:00602553170.057
lipid storageGO:001991510.057
regulation of response to stimulusGO:00485832690.055
Human
gtp metabolic processGO:004603940.055
heterocycle biosynthetic processGO:00181302150.054
skeletal system developmentGO:00015011810.053
cellular nitrogen compound metabolic processGO:00346412900.051
regulation of multicellular organism growthGO:004001440.051
meiotic nuclear divisionGO:000712640.050
positive regulation of transportGO:005105020.050
nitrogen compound metabolic processGO:00068073190.050
histone lysine demethylationGO:007007620.050
cytokinesisGO:000091030.050
cellular carbohydrate metabolic processGO:004426240.049
transcription dna templatedGO:00063511810.049
small gtpase mediated signal transductionGO:000726480.046
Human
negative regulation of signal transductionGO:0009968940.046
Human
guanosine containing compound catabolic processGO:190106920.045
positive regulation of cell cycleGO:004578730.045
regulation of cellular carbohydrate metabolic processGO:001067540.044
protein demethylationGO:000648220.044
cognitionGO:005089010.044
positive regulation of catabolic processGO:000989640.044
embryo development ending in birth or egg hatchingGO:00097922710.044
regulation of gtp catabolic processGO:003312420.044
regulation of metabolic processGO:00192223590.044
cellular component biogenesisGO:00440851780.043
gtp catabolic processGO:000618420.042
regulation of transcription dna templatedGO:00063552130.041
positive regulation of nucleotide catabolic processGO:003081310.041
lateral inhibitionGO:004633110.040
organic substance biosynthetic processGO:19015762890.039
guanosine containing compound metabolic processGO:190106840.037
cell surface receptor signaling pathwayGO:00071663250.037
gene expressionGO:00104672520.037
regulation of cell substrate adhesionGO:001081010.037
heterocycle metabolic processGO:00464832900.037
organic acid metabolic processGO:0006082310.037
regulation of rho protein signal transductionGO:003502320.036
regulation of protein complex assemblyGO:004325430.036
vacuolar transportGO:000703420.036
phagocytosis engulfmentGO:000691110.035
chemosensory behaviorGO:000763510.035
oxoacid metabolic processGO:0043436310.035
cell substrate adhesionGO:003158940.035
nucleobase containing compound biosynthetic processGO:00346542050.035
regulation of endocrine processGO:004406020.035
protein localization to nucleusGO:003450430.035
organic cyclic compound biosynthetic processGO:19013622230.034
modification dependent protein catabolic processGO:001994130.034
stem cell proliferationGO:007208940.034
positive regulation of gtpase activityGO:004354710.034
sleepGO:003043110.034
regulation of cellular biosynthetic processGO:00313262450.033
positive regulation of gtp catabolic processGO:003312610.033
positive regulation of secretion by cellGO:190353210.033
regulation of cell developmentGO:00602841000.033
regulation of nucleoside metabolic processGO:000911820.032
protein modification processGO:00362111000.032
Human
cellular aromatic compound metabolic processGO:00067252950.032
internal peptidyl lysine acetylationGO:001839320.032
negative regulation of protein phosphorylationGO:000193340.032
amine metabolic processGO:000930820.032
negative regulation of protein localization to nucleusGO:190018120.032
head developmentGO:00603223030.032
organonitrogen compound metabolic processGO:1901564740.032
regulation of cellular macromolecule biosynthetic processGO:20001122220.032
regulation of macromolecule biosynthetic processGO:00105562250.032
regulation of cellular amino acid metabolic processGO:000652100.032
macromolecular complex subunit organizationGO:0043933740.031
mitotic dna integrity checkpointGO:004477440.031
positive regulation of purine nucleotide catabolic processGO:003312310.031
response to organic substanceGO:00100331530.031
protein acetylationGO:000647320.031
proteolysis involved in cellular protein catabolic processGO:005160330.031
regulation of cellular ketone metabolic processGO:001056570.031
cellular protein modification processGO:00064641000.031
Human
cellular amino acid metabolic processGO:000652070.031
regulation of signal transductionGO:00099662250.030
Human
meiotic cell cycle processGO:190304630.030
regulation of primary metabolic processGO:00800903110.030
regulation of cell matrix adhesionGO:000195210.030
regulation of cellular metabolic processGO:00313233200.030
regulation of peptidyl tyrosine phosphorylationGO:005073010.030
protein targeting to nucleusGO:004474430.030
cellular ketone metabolic processGO:0042180110.030
rna biosynthetic processGO:00327741810.029
synaptic growth at neuromuscular junctionGO:005112420.029
central nervous system developmentGO:00074173870.029
cellular component morphogenesisGO:00329893360.029
regulation of purine nucleotide catabolic processGO:003312120.029
deathGO:00162651210.029
extrinsic apoptotic signaling pathwayGO:009719130.029
macromolecule modificationGO:00434121110.029
Human
cellular protein catabolic processGO:004425740.029
brain developmentGO:00074202930.029
small molecule metabolic processGO:0044281770.028
endosomal transportGO:001619720.028
regulation of gene expressionGO:00104682650.028
regulation of cellular amine metabolic processGO:003323800.028
regulation of establishment of protein localizationGO:007020140.028
developmental growthGO:00485891660.028
cartilage developmentGO:0051216960.028
regulation of biological qualityGO:00650082630.027
actin polymerization or depolymerizationGO:000815420.027
positive regulation of nucleoside metabolic processGO:004597910.027
single organism nuclear importGO:190259330.027
locomotor rhythmGO:004547530.027
regulation of nucleotide catabolic processGO:003081120.027
protein acylationGO:004354330.027
regulation of developmental processGO:00507932470.027
regulation of skeletal muscle tissue developmentGO:004864140.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
negative regulation of nucleocytoplasmic transportGO:004682320.026
negative regulation of ras protein signal transductionGO:004658010.026
membrane invaginationGO:001032410.026
sensory organ developmentGO:00074233930.026
ubiquitin dependent protein catabolic processGO:000651130.026
nucleic acid templated transcriptionGO:00976591810.026
lysosomal transportGO:000704120.026
post golgi vesicle mediated transportGO:000689210.026
cell projection morphogenesisGO:00488582440.026
phosphorus metabolic processGO:00067931090.026
Human
adult behaviorGO:003053420.026
cellular component assemblyGO:00226071700.026
internal protein amino acid acetylationGO:000647520.025
regulation of protein polymerizationGO:003227120.025
peptidyl lysine acetylationGO:001839420.025
aromatic compound biosynthetic processGO:00194382170.025
response to stressGO:00069502630.025
regulation of reactive oxygen species metabolic processGO:200037720.024
protein targeting to vacuoleGO:000662310.024
regulation of protein catabolic processGO:004217610.024
regulation of protein localization to nucleusGO:190018020.024
single organism metabolic processGO:00447102170.024
Human
regulation of production of molecular mediator of immune responseGO:000270010.024
cellular amine metabolic processGO:004410620.024
protein dealkylationGO:000821420.024
protein importGO:001703830.024
regulation of myotube differentiationGO:001083020.023
spindle assemblyGO:005122520.023
positive regulation of protein complex assemblyGO:003133420.023
negative regulation of cytoplasmic transportGO:190365020.023
cell matrix adhesionGO:000716040.023
regulation of stem cell differentiationGO:200073640.023
positive regulation of cell adhesionGO:004578510.023
negative regulation of tor signalingGO:003200720.023
regulation of rna biosynthetic processGO:20011412130.023
digestive system developmentGO:00551232890.023
cellular protein metabolic processGO:00442671290.023
Human
connective tissue developmentGO:0061448990.023
regulation of cell communicationGO:00106462320.023
Human
stem cell maintenanceGO:001982740.023
cell deathGO:00082191210.023
regulation of apoptotic processGO:0042981980.023
cellular response to chemical stimulusGO:00708871570.022
immune system processGO:00023762410.022
modification dependent macromolecule catabolic processGO:004363230.022
nucleocytoplasmic transportGO:000691340.022
regulation of receptor activityGO:001046920.022
protein polymerizationGO:005125840.022
regulation of transcription from rna polymerase ii promoterGO:00063571140.022
rho protein signal transductionGO:000726650.022
stem cell divisionGO:001714510.022
blood vessel developmentGO:00015682460.022
regulation of striated muscle contractionGO:000694220.022
cellular nitrogen compound biosynthetic processGO:00442712180.021
synaptic vesicle localizationGO:009747910.021
establishment of synaptic vesicle localizationGO:009748010.021
protein import into nucleusGO:000660630.021
regulation of cytoplasmic transportGO:190364940.021
hormone transportGO:000991420.021
spermatid developmentGO:000728620.021
membrane fusionGO:006102520.021
multi organism processGO:00517041340.021
cellular macromolecule biosynthetic processGO:00346452240.021
response to vitaminGO:003327330.021
hormone secretionGO:004687920.021
vasculature developmentGO:00019442780.021
nuclear importGO:005117030.021
regulation of dendrite developmentGO:005077330.020
positive regulation of map kinase activityGO:004340630.020
single organism reproductive processGO:0044702400.020
circadian sleep wake cycleGO:004274520.020
generation of neuronsGO:00486993850.020
dna templated transcription elongationGO:000635430.020
activation of mapk activityGO:000018730.020
neurotransmitter transportGO:000683620.020
cell morphogenesis involved in differentiationGO:00009041950.020
regulation of wound healingGO:006104120.020
circadian sleep wake cycle sleepGO:005080210.020
negative regulation of small gtpase mediated signal transductionGO:005105810.020
hematopoietic or lymphoid organ developmentGO:00485341910.020
cellular catabolic processGO:0044248270.020
carboxylic acid metabolic processGO:0019752220.020
growthGO:00400071740.020
response to external stimulusGO:00096052640.020
regulation of reproductive processGO:200024140.020
positive regulation of secretionGO:005104710.020
positive regulation of wound healingGO:009030310.019
rna localizationGO:000640340.019
histone h3 k4 methylationGO:005156820.019
apoptotic processGO:00069151160.019
regulation of protein targetingGO:190353320.019
positive regulation of cellular component biogenesisGO:004408930.019
regulation of autophagyGO:001050630.019
neuron differentiationGO:00301823530.019
ras protein signal transductionGO:000726570.019
Human
germ line stem cell maintenanceGO:003071820.019
negative regulation of protein kinase activityGO:000646940.019
positive regulation of cell killingGO:003134320.019
cell projection organizationGO:00300302840.019
chromosome organization involved in meiosisGO:007019210.019
muscle cell developmentGO:00550011150.019
intracellular mrna localizationGO:000829810.019
programmed cell deathGO:00125011190.019
female meiotic divisionGO:000714320.019
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.019
striated muscle cell differentiationGO:00511461290.019
regulation of erk1 and erk2 cascadeGO:007037240.019
muscle cell differentiationGO:00426921390.018
positive regulation of metabolic processGO:00098931080.018
phosphatidylinositol 3 kinase signalingGO:001406520.018
regulation of hormone secretionGO:004688320.018
meiotic chromosome segregationGO:004513230.018
regulation of stem cell proliferationGO:007209120.018
response to drugGO:004249330.018
positive regulation of cell divisionGO:005178120.018
regulation of multicellular organismal processGO:00512392770.018
histone modificationGO:0016570200.018
neuron developmentGO:00486662620.018
system processGO:00030081850.018
regulation of protein transportGO:005122330.018
regulation of organ growthGO:004662030.018
tissue remodelingGO:004877140.018
endocrine processGO:005088620.017
regulation of synaptic plasticityGO:004816710.017
striated muscle cell developmentGO:00550021080.017
negative regulation of biosynthetic processGO:0009890550.017
negative regulation of cellular processGO:00485232830.017
Human
chromatin organizationGO:0006325220.017
microtubule organizing center organizationGO:003102310.017
negative regulation of protein import into nucleusGO:004230820.017
regulation of protein modification by small protein conjugation or removalGO:190332030.017
regulation of signalingGO:00230512350.017
Human
cellular component disassemblyGO:002241110.017
regulation of cell shapeGO:000836010.017
positive regulation of striated muscle tissue developmentGO:004584410.017
golgi vesicle transportGO:004819330.017
regulation of tube sizeGO:003515020.017
oocyte maturationGO:000155640.017
negative regulation of nucleobase containing compound metabolic processGO:0045934590.017
erk1 and erk2 cascadeGO:007037140.017
positive regulation of nucleobase containing compound metabolic processGO:0045935690.017
cell agingGO:000756920.017
neurological system processGO:0050877620.017
regulation of neurotransmitter secretionGO:004692810.017
cellular component assembly involved in morphogenesisGO:00109271070.017
protein secretionGO:000930610.017
regulation of blood vessel sizeGO:005088020.017
single organism localizationGO:19025782250.017
chordate embryonic developmentGO:00430092710.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
regulation of intracellular signal transductionGO:1902531570.017
neuroblast proliferationGO:000740520.017
regulation of meiotic cell cycleGO:005144510.017
positive regulation of carbohydrate metabolic processGO:004591310.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
negative regulation of kinase activityGO:003367340.017
negative regulation of cellular catabolic processGO:003133030.017
regionalizationGO:00030022740.016
regulation of intracellular protein transportGO:003315730.016
chromosome organizationGO:0051276310.016
regulation of carbohydrate metabolic processGO:000610940.016
negative regulation of metabolic processGO:0009892860.016
cell part morphogenesisGO:00329902460.016
histone h3 k9 demethylationGO:003316920.016
regulation of gtpase activityGO:004308720.016
regulation of neuron differentiationGO:0045664560.016
symbiosis encompassing mutualism through parasitismGO:004440340.016
positive regulation of erk1 and erk2 cascadeGO:007037420.016
dorsal ventral pattern formationGO:00099531250.016
regulation of synapse organizationGO:005080730.016
g2 dna damage checkpointGO:003157230.016
negative regulation of protein transportGO:005122430.016
mitotic g2 m transition checkpointGO:004481830.016
organelle fusionGO:004828430.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
actin filament polymerizationGO:003004120.016
cellular response to external stimulusGO:007149620.016
regulation of ras gtpase activityGO:003231820.015
centrosome organizationGO:005129710.015
protein heterooligomerizationGO:005129110.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
development of primary female sexual characteristicsGO:004654540.015
somatic muscle developmentGO:000752540.015
regulation of phosphate metabolic processGO:0019220430.015
cell motilityGO:00488702440.015
actin filament based processGO:0030029640.015
single organism transportGO:00447652060.015
peptide transportGO:001583310.015
endocrine hormone secretionGO:006098620.015
positive regulation of jnk cascadeGO:004633030.015
negative regulation of intracellular transportGO:003238730.015
interspecies interaction between organismsGO:004441940.015
cellular response to nutrient levelsGO:003166920.015
muscle structure developmentGO:00610611960.015
cell migrationGO:00164772370.015
proteasomal protein catabolic processGO:001049820.015
positive regulation of canonical wnt signaling pathwayGO:009026340.015
tube morphogenesisGO:00352393490.015
protein localization to plasma membraneGO:007265910.015
regulation of cell activationGO:005086510.015
phosphate containing compound metabolic processGO:00067961080.015
Human
transcription from rna polymerase ii promoterGO:0006366800.015
protein dephosphorylationGO:000647030.015
positive regulation of cell activationGO:005086710.015
sensory organ morphogenesisGO:00905962000.015
cellular component movementGO:00069283350.015
protein complex disassemblyGO:004324110.015
adherens junction organizationGO:003433240.015
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
single organism membrane fusionGO:004480120.015
positive regulation of cellular processGO:00485222010.014
circadian sleep wake cycle processGO:002241020.014
embryonic limb morphogenesisGO:003032620.014
primary neural tube formationGO:001402010.014
negative regulation of cell communicationGO:0010648960.014
Human
positive regulation of cellular amino acid metabolic processGO:004576400.014
positive regulation of protein polymerizationGO:003227320.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
intracellular signal transductionGO:0035556850.014
Human
cell morphogenesisGO:00009022890.014
neural crest formationGO:0014029140.014
negative regulation of catabolic processGO:000989530.014
epithelial cell differentiationGO:00308551160.014
negative regulation of chromosome organizationGO:200125110.014
production of molecular mediator of immune responseGO:000244020.014
pigmentationGO:0043473850.014
positive regulation of cellular amine metabolic processGO:003324000.014
regulation of nucleocytoplasmic transportGO:004682220.014
regulation of programmed cell deathGO:00430671010.014
neurotransmitter secretionGO:000726920.014
response to hexoseGO:000974630.014
regulation of dna replicationGO:000627530.014
negative regulation of synapse assemblyGO:005196420.014
regulation of chromosome segregationGO:005198310.014
negative regulation of signalingGO:0023057960.014
Human
protein localization to vacuoleGO:007266510.014
post embryonic organ developmentGO:004856940.014
establishment of protein localization to plasma membraneGO:009000210.014
establishment of protein localization to vacuoleGO:007266610.014
regulation of circadian sleep wake cycle sleepGO:004518710.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
digestive tract morphogenesisGO:00485462310.014
immune system developmentGO:00025201910.014
cellular response to starvationGO:000926710.014
carbohydrate biosynthetic processGO:001605110.014
regulation of circadian rhythmGO:004275240.014
response to growth factorGO:0070848390.014
regulation of protein import into nucleusGO:004230620.014
negative regulation of nucleic acid templated transcriptionGO:1903507450.013
endosome organizationGO:000703220.013
transcription elongation from rna polymerase ii promoterGO:000636830.013
negative regulation of rna biosynthetic processGO:1902679450.013
macromolecular complex disassemblyGO:003298410.013
cellular response to organic substanceGO:00713101050.013
embryonic organ developmentGO:00485683810.013
regulation of circadian sleep wake cycleGO:004274910.013
regulation of oocyte developmentGO:006028130.013
germ line stem cell divisionGO:004207810.013
camera type eye developmentGO:00430102220.013
pathway restricted smad protein phosphorylationGO:006038910.013
synaptic vesicle recyclingGO:003646510.013
macromolecular complex assemblyGO:0065003350.013
negative regulation of epithelial cell proliferationGO:005068010.013
female sex differentiationGO:004666040.013
cytoplasm organizationGO:000702840.013
lens fiber cell morphogenesisGO:007030930.013
digestive tract developmentGO:00485652650.013
inner ear developmentGO:00488391260.013
regulation of epithelial cell proliferationGO:005067830.013
regulation of synapse assemblyGO:005196330.013
catabolic processGO:0009056320.013
regulation of rna metabolic processGO:00512522240.013
regulation of epithelial to mesenchymal transitionGO:001071730.013
single fertilizationGO:000733830.013
phosphorylationGO:0016310690.013
Human
nucleic acid transportGO:005065720.013
phagosome maturationGO:009038210.013
compound eye developmentGO:004874920.013
regulation of cell deathGO:00109411030.013
wnt signaling pathwayGO:0016055800.013
taxisGO:00423301090.013
cellular response to stressGO:0033554620.013
cellular response to oxygen levelsGO:007145310.013
determination of left right symmetryGO:00073681790.013
positive regulation of gene expressionGO:0010628710.013
eye developmentGO:00016542770.013
cellular response to extracellular stimulusGO:003166820.013
protein stabilizationGO:005082120.013
insulin like growth factor receptor signaling pathwayGO:004800940.013
regulation of muscle contractionGO:000693730.013
fertilizationGO:000956630.012
regulation of intracellular phGO:005145310.012
carbohydrate homeostasisGO:003350010.012
female gonad developmentGO:000858540.012
regulation of hydrolase activityGO:0051336280.012
cellular monovalent inorganic cation homeostasisGO:003000420.012
mesoderm developmentGO:0007498880.012
pigment cell differentiationGO:0050931380.012
negative regulation of intracellular protein transportGO:009031730.012
centrosome cycleGO:000709810.012
neuronal action potentialGO:0019228180.012
neuron neuron synaptic transmissionGO:000727010.012
regulation of dendrite morphogenesisGO:004881430.012
positive regulation of nitrogen compound metabolic processGO:0051173690.012
peptide metabolic processGO:000651810.012
entrainment of circadian clockGO:000964920.012
response to antibioticGO:004667710.012
positive regulation of cytoskeleton organizationGO:005149530.012
locomotionGO:00400113130.012
tube closureGO:006060610.012
lipid metabolic processGO:0006629520.012
negative regulation of cellular biosynthetic processGO:0031327550.012
negative regulation of response to stimulusGO:00485851040.012
Human
regulation of localizationGO:00328791040.012
protein complex assemblyGO:0006461300.012
reproductionGO:0000003400.012
nitric oxide metabolic processGO:004620920.012
regulation of multicellular organismal developmentGO:20000262230.012
lens fiber cell developmentGO:007030730.012
negative regulation of histone modificationGO:003105710.012
reactive oxygen species biosynthetic processGO:190340910.012
regulation of systemic arterial blood pressureGO:000307310.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
regulation of p38mapk cascadeGO:190074410.011
double strand break repairGO:000630230.011
positive regulation of gliogenesisGO:001401520.011
cell cycleGO:0007049930.011
regulation of phGO:000688530.011
positive regulation of apoptotic signaling pathwayGO:200123510.011
regulation of skeletal muscle fiber developmentGO:004874220.011
gastrulationGO:00073692080.011
neuron remodelingGO:001632210.011
regulation of dna recombinationGO:000001820.011
liver developmentGO:0001889960.011
regulation of bindingGO:005109830.011
response to carbohydrateGO:000974330.011
neuromuscular process controlling balanceGO:005088530.011
localization of cellGO:00516742440.011
regulation of cell differentiationGO:00455951420.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
eye morphogenesisGO:00485921440.011
peptidyl threonine phosphorylationGO:001810710.011
negative regulation of mapk cascadeGO:004340940.011
sex determinationGO:000753010.011
nuclear transportGO:005116940.011
morphogenesis of an epitheliumGO:00020093330.011

brap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
nervous system diseaseDOID:86300.020
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
organ system cancerDOID:005068600.014
disease of metabolismDOID:001466700.013
musculoskeletal system diseaseDOID:1700.012
inherited metabolic disorderDOID:65500.011