Danio rerio

0 known processes

phex

phosphate regulating gene with homologues to endopeptidases on the X chromosome

(Aliases: wu:fx03e08)

phex biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
glucose importGO:004632320.362
central nervous system developmentGO:00074173870.210
gland developmentGO:00487321430.149
mesoderm developmentGO:0007498880.141
larval developmentGO:000216420.140
regulation of glucose importGO:004632410.119
agingGO:000756820.114
regulation of glucose transportGO:001082710.100
neuroblast proliferationGO:000740520.099
nucleic acid templated transcriptionGO:00976591810.094
positive regulation of transportGO:005105020.093
camera type eye morphogenesisGO:00485931080.091
stem cell proliferationGO:007208940.086
positive regulation of glucose transportGO:001082810.083
muscle cell differentiationGO:00426921390.080
response to carbohydrateGO:000974330.079
single organism transportGO:00447652060.074
hepaticobiliary system developmentGO:0061008980.071
single organism localizationGO:19025782250.069
nuclear migrationGO:000709730.064
transportGO:00068102200.063
cellular amine metabolic processGO:004410620.062
regulation of response to stimulusGO:00485832690.061
embryonic organ developmentGO:00485683810.059
cellular nitrogen compound biosynthetic processGO:00442712180.059
single organism organelle organizationGO:19025891990.058
positive regulation of cellular component biogenesisGO:004408930.058
astrocyte differentiationGO:004870810.058
single organism metabolic processGO:00447102170.058
single organism cellular localizationGO:1902580460.056
response to stressGO:00069502630.055
response to biotic stimulusGO:0009607970.054
tissue regenerationGO:0042246740.054
cellular response to organic substanceGO:00713101050.052
response to woundingGO:00096111160.052
cellular macromolecule biosynthetic processGO:00346452240.052
camera type eye developmentGO:00430102220.052
morphogenesis of an epitheliumGO:00020093330.051
regulation of extrinsic apoptotic signaling pathwayGO:200123630.051
organelle localizationGO:0051640490.049
leukocyte proliferationGO:007066110.049
regulation of stem cell differentiationGO:200073640.048
response to monosaccharideGO:003428430.048
liver developmentGO:0001889960.048
regulation of biological qualityGO:00650082630.048
reactive nitrogen species metabolic processGO:200105700.048
response to chemicalGO:00422213200.045
regulation of cell activationGO:005086510.045
regulation of protein localization to nucleusGO:190018020.044
establishment of protein localization to organelleGO:007259440.044
catechol containing compound metabolic processGO:000971220.044
germ line stem cell divisionGO:004207810.043
muscle organ developmentGO:00075171010.043
negative regulation of biological processGO:00485193040.042
skeletal system developmentGO:00015011810.042
cell fate commitmentGO:0045165990.041
response to hexoseGO:000974630.041
negative regulation of cellular processGO:00485232830.041
sensory organ developmentGO:00074233930.041
tube morphogenesisGO:00352393490.040
eye morphogenesisGO:00485921440.040
medulla oblongata developmentGO:002155040.040
biosynthetic processGO:00090582940.040
regulation of leukocyte mediated immunityGO:000270310.040
nuclear transportGO:005116940.040
blood vessel morphogenesisGO:00485142160.040
positive regulation of catabolic processGO:000989640.040
positive regulation of glucose importGO:004632610.040
vasculature developmentGO:00019442780.039
response to transition metal nanoparticleGO:1990267280.039
guanosine containing compound metabolic processGO:190106840.039
protein localization to nucleusGO:003450430.039
positive regulation of map kinase activityGO:004340630.039
extrinsic apoptotic signaling pathwayGO:009719130.039
mononuclear cell proliferationGO:003294310.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.037
transcription dna templatedGO:00063511810.037
kidney developmentGO:0001822920.037
heterocycle biosynthetic processGO:00181302150.036
regulation of production of molecular mediator of immune responseGO:000270010.036
regulation of rna biosynthetic processGO:20011412130.036
regulation of phGO:000688530.036
stem cell divisionGO:001714510.036
regulation of cytokine productionGO:000181730.036
homeostatic processGO:00425921420.036
type b pancreatic cell developmentGO:000332340.036
urogenital system developmentGO:0001655970.036
cellular nitrogen compound metabolic processGO:00346412900.035
multi organism cellular processGO:004476420.035
amine metabolic processGO:000930820.035
negative regulation of secretion by cellGO:190353120.035
regulation of signalingGO:00230512350.034
organonitrogen compound metabolic processGO:1901564740.034
cellular response to estrogen stimulusGO:0071391240.033
production of molecular mediator of immune responseGO:000244020.033
organic acid metabolic processGO:0006082310.033
gtp catabolic processGO:000618420.033
hemopoiesisGO:00300971830.033
myeloid leukocyte mediated immunityGO:000244410.033
cell projection organizationGO:00300302840.033
organelle organizationGO:00069962270.032
synaptic growth at neuromuscular junctionGO:005112420.032
embryo development ending in birth or egg hatchingGO:00097922710.032
regulation of phospholipase c activityGO:190027410.031
phosphate containing compound metabolic processGO:00067961080.031
regulation of multicellular organism growthGO:004001440.031
response to nutrientGO:000758430.031
positive regulation of lipase activityGO:006019310.031
organic substance biosynthetic processGO:19015762890.031
modulation by virus of host morphology or physiologyGO:001904810.031
regulation of autophagyGO:001050630.030
viral processGO:001603210.030
regulation of cellular amine metabolic processGO:003323800.030
nucleocytoplasmic transportGO:000691340.029
adherens junction organizationGO:003433240.029
regulation of cell differentiationGO:00455951420.029
monovalent inorganic cation transportGO:0015672420.029
nucleobase containing compound biosynthetic processGO:00346542050.029
dorsal motor nucleus of vagus nerve developmentGO:002174440.028
multi organism processGO:00517041340.028
ameboidal type cell migrationGO:00016671430.028
embryonic organ morphogenesisGO:00485622740.028
lymphocyte proliferationGO:004665110.028
positive regulation of gliogenesisGO:001401520.027
negative regulation of protein phosphorylationGO:000193340.027
axonogenesisGO:00074091520.027
organic cyclic compound biosynthetic processGO:19013622230.027
chordate embryonic developmentGO:00430092710.027
protein localization to plasma membraneGO:007265910.027
spinal cord developmentGO:0021510460.027
muscle structure developmentGO:00610611960.027
cellular localizationGO:0051641970.027
regulation of anatomical structure morphogenesisGO:00226031300.027
cellular carbohydrate metabolic processGO:004426240.027
neural tube developmentGO:0021915620.027
regulation of synapse organizationGO:005080730.027
protein localizationGO:0008104400.026
nuclear importGO:005117030.026
primary amino compound biosynthetic processGO:190116210.026
anatomical structure homeostasisGO:0060249360.026
regulation of cell deathGO:00109411030.026
male meiosisGO:000714020.026
regulation of multicellular organismal processGO:00512392770.026
gtp metabolic processGO:004603940.025
mitochondrion organizationGO:000700540.025
positive regulation of biological processGO:00485182530.025
cell proliferationGO:0008283800.025
protein complex assemblyGO:0006461300.025
rna metabolic processGO:00160702190.025
establishment of localizationGO:00512342440.025
cell cycleGO:0007049930.025
hematopoietic or lymphoid organ developmentGO:00485341910.025
nitrogen compound metabolic processGO:00068073190.025
regulation of cell communicationGO:00106462320.025
negative regulation of intracellular transportGO:003238730.025
regulation of cellular carbohydrate metabolic processGO:001067540.025
generation of neuronsGO:00486993850.024
cellular macromolecule metabolic processGO:00442603910.024
regulation of canonical wnt signaling pathwayGO:0060828340.024
tissue remodelingGO:004877140.024
positive regulation of cell activationGO:005086710.024
maintenance of locationGO:005123540.024
b cell mediated immunityGO:001972430.024
embryonic pattern specificationGO:0009880440.024
regulation of nitrogen compound metabolic processGO:00511712510.024
regulation of macromolecule biosynthetic processGO:00105562250.023
endothelial cell developmentGO:0001885120.023
cell migrationGO:00164772370.023
wnt signaling pathwayGO:0016055800.023
macromolecular complex subunit organizationGO:0043933740.023
exocytosisGO:000688710.023
positive regulation of immune effector processGO:000269930.023
one carbon compound transportGO:0019755140.023
response to organic cyclic compoundGO:0014070510.023
energy reserve metabolic processGO:000611220.022
determination of bilateral symmetryGO:00098552040.022
regulation of establishment of protein localizationGO:007020140.022
muscle fiber developmentGO:0048747520.022
phagocytosisGO:000690930.022
response to glucoseGO:000974930.022
brain developmentGO:00074202930.022
establishment of spindle orientationGO:0051294100.022
chemical homeostasisGO:0048878490.022
renal system developmentGO:0072001940.022
catechol containing compound biosynthetic processGO:000971320.021
autophagyGO:000691440.021
signal transductionGO:00071654550.021
gene expressionGO:00104672520.021
positive regulation of cell communicationGO:0010647560.021
response to endogenous stimulusGO:0009719830.021
immunoglobulin mediated immune responseGO:001606430.021
catecholamine biosynthetic processGO:004242320.021
positive regulation of cellular catabolic processGO:003133130.021
immune system processGO:00023762410.021
intracellular transportGO:0046907320.021
deathGO:00162651210.021
digestive tract developmentGO:00485652650.021
digestive tract morphogenesisGO:00485462310.021
eye developmentGO:00016542770.021
cellular response to organic cyclic compoundGO:0071407380.021
circulatory system processGO:0003013870.021
response to other organismGO:0051707970.020
regulation of neural precursor cell proliferationGO:200017730.020
cellular response to extracellular stimulusGO:003166820.020
central nervous system neuron differentiationGO:0021953740.020
guanosine containing compound catabolic processGO:190106920.020
response to estrogenGO:0043627270.020
single organism nuclear importGO:190259330.020
positive regulation of jnk cascadeGO:004633030.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.020
carboxylic acid metabolic processGO:0019752220.019
developmental cell growthGO:0048588520.019
cell morphogenesis involved in neuron differentiationGO:00486671630.019
regulation of reproductive processGO:200024140.019
negative regulation of immune responseGO:005077720.019
blood circulationGO:0008015870.019
establishment or maintenance of cell polarityGO:0007163290.019
regulation of sodium ion transportGO:000202820.019
digestive tract mesoderm developmentGO:000750210.019
b cell activationGO:004211320.019
heterocycle metabolic processGO:00464832900.019
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.019
female sex differentiationGO:004666040.019
cellular response to external stimulusGO:007149620.019
cellular component morphogenesisGO:00329893360.019
cellular biosynthetic processGO:00442492860.019
protein importGO:001703830.019
response to uvGO:000941130.018
developmental growth involved in morphogenesisGO:0060560860.018
negative regulation of protein serine threonine kinase activityGO:007190120.018
regulation of myotube differentiationGO:001083020.018
heart developmentGO:00075073130.018
organelle assemblyGO:00709251100.018
interspecies interaction between organismsGO:004441940.018
striated muscle cell developmentGO:00550021080.018
cellular response to decreased oxygen levelsGO:003629410.018
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.018
negative regulation of cell communicationGO:0010648960.018
specification of symmetryGO:00097992040.017
macromolecule modificationGO:00434121110.017
growthGO:00400071740.017
regulation of bindingGO:005109830.017
regenerationGO:0031099910.017
myotube cell developmentGO:0014904350.017
regulation of purine nucleotide catabolic processGO:003312120.017
oxoacid metabolic processGO:0043436310.017
symbiosis encompassing mutualism through parasitismGO:004440340.017
internal protein amino acid acetylationGO:000647520.017
multicellular organism growthGO:003526440.017
hydrogen peroxide metabolic processGO:004274320.017
cellular response to chemical stimulusGO:00708871570.017
macromolecule localizationGO:0033036540.016
regulation of immune system processGO:0002682340.016
peptidyl lysine acetylationGO:001839420.016
regulation of transmembrane transporter activityGO:002289820.016
cellular component biogenesisGO:00440851780.016
regulation of carbohydrate metabolic processGO:000610940.016
regulation of immunoglobulin productionGO:000263710.016
morphogenesis of an epithelial sheetGO:0002011490.016
protein import into nucleusGO:000660630.016
cartilage condensationGO:000150230.016
negative regulation of ras protein signal transductionGO:004658010.016
cellular response to starvationGO:000926710.016
angiogenesisGO:00015251580.016
regulation of stem cell proliferationGO:007209120.016
muscle tissue developmentGO:00605371100.015
cortical cytoskeleton organizationGO:003086510.015
cellular amino acid metabolic processGO:000652070.015
activation of mapk activityGO:000018730.015
regulation of mrna catabolic processGO:006101330.015
nitric oxide metabolic processGO:004620920.015
apical protein localizationGO:004517660.015
regulation of vasculature developmentGO:1901342330.015
regulation of mrna processingGO:005068430.015
heart processGO:0003015710.015
circadian sleep wake cycleGO:004274520.015
retina morphogenesis in camera type eyeGO:0060042790.015
striated muscle cell differentiationGO:00511461290.015
embryonic retina morphogenesis in camera type eyeGO:0060059220.015
organic cyclic compound metabolic processGO:19013603010.015
cell morphogenesis involved in differentiationGO:00009041950.015
peptide transportGO:001583310.015
neuron projection guidanceGO:0097485860.015
epidermal cell differentiationGO:0009913360.015
cellular component movementGO:00069283350.015
behaviorGO:0007610740.015
cell morphogenesisGO:00009022890.015
positive regulation of stress activated mapk cascadeGO:003287430.015
spindle localizationGO:0051653120.015
ear developmentGO:00435831270.015
regulation of mitochondrion organizationGO:001082110.015
regulation of ion transmembrane transporter activityGO:003241220.015
small molecule metabolic processGO:0044281770.015
regulation of nucleoside metabolic processGO:000911820.014
establishment of localization in cellGO:0051649770.014
adult behaviorGO:003053420.014
skeletal system morphogenesisGO:00487051020.014
regulation of nucleocytoplasmic transportGO:004682220.014
connective tissue developmentGO:0061448990.014
regulation of wnt signaling pathwayGO:0030111530.014
gastrulationGO:00073692080.014
regulation of oocyte developmentGO:006028130.014
response to amineGO:001407510.014
negative regulation of response to stimulusGO:00485851040.014
establishment of apical basal cell polarityGO:003508920.014
regulation of developmental processGO:00507932470.014
endothelial cell migrationGO:0043542190.014
organic substance transportGO:0071702580.014
skeletal muscle fiber developmentGO:0048741350.014
regulation of cytoplasmic transportGO:190364940.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
melanin metabolic processGO:000658220.014
germ line stem cell maintenanceGO:003071820.014
lipid metabolic processGO:0006629520.014
superoxide metabolic processGO:000680120.013
cellular response to endogenous stimulusGO:0071495680.013
regulation of signal transductionGO:00099662250.013
negative regulation of secretionGO:005104820.013
regulation of jun kinase activityGO:004350630.013
immunoglobulin productionGO:000237710.013
epithelial tube morphogenesisGO:00605621480.013
cell projection morphogenesisGO:00488582440.013
response to corticosteroidGO:003196010.013
regulation of reactive oxygen species metabolic processGO:200037720.013
developmental maturationGO:0021700340.013
serotonin metabolic processGO:004242810.013
proteolysisGO:0006508380.013
leukocyte mediated immunityGO:000244360.013
cation transportGO:0006812810.013
biological adhesionGO:0022610400.013
regulation of epithelial to mesenchymal transitionGO:001071730.013
chemotaxisGO:00069351040.013
regulation of skeletal muscle fiber developmentGO:004874220.012
positive regulation of cell deathGO:0010942290.012
regulation of biosynthetic processGO:00098892500.012
glycerolipid biosynthetic processGO:004501710.012
programmed cell deathGO:00125011190.012
reactive oxygen species biosynthetic processGO:190340910.012
embryonic camera type eye developmentGO:0031076290.012
stem cell maintenanceGO:001982740.012
morphogenesis of embryonic epitheliumGO:0016331300.012
positive regulation of signal transductionGO:0009967560.012
canonical wnt signaling pathwayGO:0060070480.012
regulation of growth rateGO:004000910.012
negative regulation of hormone secretionGO:004688820.012
epithelial cell differentiationGO:00308551160.012
digestive system developmentGO:00551232890.012
regulation of transporter activityGO:003240920.012
cortical actin cytoskeleton organizationGO:003086610.012
retina development in camera type eyeGO:00600411460.012
dopamine biosynthetic processGO:004241620.012
epidermis developmentGO:0008544480.012
neuron projection extensionGO:1990138450.012
positive regulation of cellular carbohydrate metabolic processGO:001067610.012
determination of heart left right asymmetryGO:00613711170.012
regulation of muscle contractionGO:000693730.012
response to growth factorGO:0070848390.012
positive regulation of cell adhesionGO:004578510.012
response to external biotic stimulusGO:0043207970.012
protein acylationGO:004354330.012
response to abiotic stimulusGO:00096281220.012
phosphorus metabolic processGO:00067931090.012
female gonad developmentGO:000858540.012
carbohydrate derivative metabolic processGO:1901135610.011
negative regulation of kinase activityGO:003367340.011
regulation of programmed cell deathGO:00430671010.011
axon extensionGO:0048675450.011
positive regulation of secretion by cellGO:190353210.011
response to vitaminGO:003327330.011
ubiquitin dependent protein catabolic processGO:000651130.011
positive regulation of positive chemotaxisGO:005092740.011
cellular protein modification processGO:00064641000.011
regulation of primary metabolic processGO:00800903110.011
cell deathGO:00082191210.011
dopamine metabolic processGO:004241720.011
positive regulation of jun kinase activityGO:004350720.011
embryonic hemopoiesisGO:0035162530.011
negative regulation of signal transductionGO:0009968940.011
sodium ion transportGO:0006814240.011
developmental growthGO:00485891660.011
cellular response to oxygen levelsGO:007145310.011
positive regulation of response to stimulusGO:0048584800.011
internal peptidyl lysine acetylationGO:001839320.011
regulation of tube sizeGO:003515020.011
regulation of cellular biosynthetic processGO:00313262450.011
endoderm developmentGO:0007492490.011
protein targeting to nucleusGO:004474430.011
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100100.011
peptidyl serine phosphorylationGO:001810510.011
regulation of cellular component movementGO:0051270550.011
rna biosynthetic processGO:00327741810.011
single organism biosynthetic processGO:0044711710.011
oocyte maturationGO:000155640.011
cell motilityGO:00488702440.011
response to glucocorticoidGO:005138410.011
cell maturationGO:0048469230.011
response to ketoneGO:190165410.011
regulation of exocytosisGO:001715710.011
neuron projection morphogenesisGO:00488121610.011
membrane fusionGO:006102520.011
wound healingGO:0042060900.011
negative regulation of cytokine productionGO:000181810.011
response to estradiolGO:003235560.011
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.011
axon guidanceGO:0007411860.011
regulation of metal ion transportGO:001095940.011
cognitionGO:005089010.011
regulation of circadian rhythmGO:004275240.011
determination of ventral identityGO:0048264210.010
carbohydrate biosynthetic processGO:001605110.010
regulation of cellular component sizeGO:0032535300.010
myotube differentiationGO:0014902450.010
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.010
response to hydrogen peroxideGO:004254230.010
neural nucleus developmentGO:0048857150.010
lipid storageGO:001991510.010
regulation of protein complex assemblyGO:004325430.010
positive regulation of cell cycleGO:004578730.010
regulation of metabolic processGO:00192223590.010
positive regulation of synapse assemblyGO:005196510.010
regulation of protein import into nucleusGO:004230620.010
regulation of protein targetingGO:190353320.010
taxisGO:00423301090.010
smad protein complex assemblyGO:000718310.010
synaptic vesicle transportGO:004848910.010
axon developmentGO:00615641660.010
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.010
negative regulation of jnk cascadeGO:004632910.010
macromolecule biosynthetic processGO:00090592270.010
regulation of neuron differentiationGO:0045664560.010
nitric oxide biosynthetic processGO:000680920.010

phex disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.107
musculoskeletal system diseaseDOID:1700.076
muscle tissue diseaseDOID:6600.035
muscular diseaseDOID:008000000.035
myopathyDOID:42300.035
nervous system diseaseDOID:86300.011
centronuclear myopathyDOID:1471700.010