IMP: Integrative Multi-species Prediction

Danio rerio

18 known processes

kiss1ra

KISS1 receptor a

(Aliases: kiss1r,si:dkey-31m5.9,kiss1rl,gpr54)

Entrez: 561898
Ensembl: ENSDARG00000002728
ZFIN: ZDB-GENE-070912-521
UniProtKB: A8CAH3
UniProtKB: F1R5R4

Process Predictions
Disease Predictions

kiss1ra biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
urea transport	GO:0015840	11	0.384
carbon dioxide transmembrane transport	GO:0035378	1	0.368
eye development	GO:0001654	277	0.256
ammonium transmembrane transport	GO:0072488	2	0.212
transport	GO:0006810	220	0.193
sensory organ development	GO:0007423	393	0.191
g protein coupled receptor signaling pathway	GO:0007186	74	0.154
camera type eye development	GO:0043010	222	0.151
urea transmembrane transport	GO:0071918	9	0.149
positive regulation of cellular component biogenesis	GO:0044089	3	0.140
positive regulation of transport	GO:0051050	2	0.129
single organism transport	GO:0044765	206	0.128
heterocycle metabolic process	GO:0046483	290	0.127	Zebrafish
regulation of dendrite development	GO:0050773	3	0.103
long chain fatty acid transport	GO:0015909	1	0.095
cellular response to estrogen stimulus	GO:0071391	24	0.092
fluid transport	GO:0042044	17	0.089
gene expression	GO:0010467	252	0.081	Zebrafish
actomyosin structure organization	GO:0031032	53	0.081
signal transduction	GO:0007165	455	0.079
glycerol transport	GO:0015793	7	0.078
establishment of localization	GO:0051234	244	0.074
opioid receptor signaling pathway	GO:0038003	3	0.074	Zebrafish
nucleotide biosynthetic process	GO:0009165	21	0.074
ion transport	GO:0006811	114	0.072
response to organic substance	GO:0010033	153	0.071
cell surface receptor signaling pathway	GO:0007166	325	0.071
localization of cell	GO:0051674	244	0.070
larval development	GO:0002164	2	0.067
system process	GO:0003008	185	0.065
guanosine containing compound catabolic process	GO:1901069	2	0.064
locomotion	GO:0040011	313	0.064
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.062	Zebrafish
regulation of biological quality	GO:0065008	263	0.060
negative regulation of biological process	GO:0048519	304	0.055
neurotransmitter secretion	GO:0007269	2	0.055
cellular macromolecule metabolic process	GO:0044260	391	0.054	Zebrafish
neurological system process	GO:0050877	62	0.053
nucleobase containing compound metabolic process	GO:0006139	274	0.053	Zebrafish
gas transport	GO:0015669	3	0.053
carbon dioxide transport	GO:0015670	3	0.050
gtp metabolic process	GO:0046039	4	0.049
regulation of gene expression	GO:0010468	265	0.048	Zebrafish
response to corticosteroid	GO:0031960	1	0.048
stem cell division	GO:0017145	1	0.047
organelle organization	GO:0006996	227	0.044
renal absorption	GO:0070293	1	0.044
maintenance of location	GO:0051235	4	0.043
response to external stimulus	GO:0009605	264	0.043
meiotic nuclear division	GO:0007126	4	0.043
cellular component assembly	GO:0022607	170	0.043
generation of neurons	GO:0048699	385	0.043
one carbon compound transport	GO:0019755	14	0.042
positive regulation of macromolecule biosynthetic process	GO:0010557	59	0.041	Zebrafish
cellular component biogenesis	GO:0044085	178	0.041
cellular aromatic compound metabolic process	GO:0006725	295	0.040	Zebrafish
heterocycle biosynthetic process	GO:0018130	215	0.040	Zebrafish
cellular protein metabolic process	GO:0044267	129	0.040
guanosine containing compound metabolic process	GO:1901068	4	0.039
rna metabolic process	GO:0016070	219	0.038	Zebrafish
aging	GO:0007568	2	0.038
macromolecule modification	GO:0043412	111	0.038
regulation of metal ion transport	GO:0010959	4	0.037
nucleobase containing compound biosynthetic process	GO:0034654	205	0.037	Zebrafish
inner ear development	GO:0048839	126	0.036
carboxylic acid metabolic process	GO:0019752	22	0.035
regulation of cell communication	GO:0010646	232	0.035
negative regulation of cellular process	GO:0048523	283	0.035
regulation of gtp catabolic process	GO:0033124	2	0.035
macromolecular complex subunit organization	GO:0043933	74	0.035
response to glucocorticoid	GO:0051384	1	0.034
cellular nitrogen compound metabolic process	GO:0034641	290	0.034	Zebrafish
actin cytoskeleton organization	GO:0030036	63	0.034
head development	GO:0060322	303	0.033
transcription dna templated	GO:0006351	181	0.033	Zebrafish
regulation of nucleotide catabolic process	GO:0030811	2	0.032
fatty acid transport	GO:0015908	1	0.032
neurotransmitter transport	GO:0006836	2	0.032
long chain fatty acid metabolic process	GO:0001676	1	0.032
stem cell proliferation	GO:0072089	4	0.032
organic cyclic compound metabolic process	GO:1901360	301	0.032	Zebrafish
phosphorylation	GO:0016310	69	0.031
stem cell fate commitment	GO:0048865	1	0.031
protein modification process	GO:0036211	100	0.030
forebrain development	GO:0030900	96	0.030
fatty acid biosynthetic process	GO:0006633	4	0.030
regulation of cell differentiation	GO:0045595	142	0.029
regulation of myotube differentiation	GO:0010830	2	0.029
aromatic compound biosynthetic process	GO:0019438	217	0.028	Zebrafish
single organism localization	GO:1902578	225	0.028
central nervous system development	GO:0007417	387	0.028
behavior	GO:0007610	74	0.027
regulation of cellular metabolic process	GO:0031323	320	0.027	Zebrafish
amine metabolic process	GO:0009308	2	0.027
defense response	GO:0006952	47	0.027
ion transmembrane transport	GO:0034220	91	0.027
cellular amine metabolic process	GO:0044106	2	0.026
phagocytosis	GO:0006909	3	0.026
cell motility	GO:0048870	244	0.026
cell migration	GO:0016477	237	0.026
positive regulation of cell cycle	GO:0045787	3	0.026
cellular component morphogenesis	GO:0032989	336	0.026
regulation of multicellular organism growth	GO:0040014	4	0.026
regulation of transcription dna templated	GO:0006355	213	0.026	Zebrafish
cellular component movement	GO:0006928	335	0.026
regulation of primary metabolic process	GO:0080090	311	0.026	Zebrafish
response to stress	GO:0006950	263	0.025
lens development in camera type eye	GO:0002088	22	0.025
monocarboxylic acid transport	GO:0015718	5	0.025
positive regulation of biological process	GO:0048518	253	0.025	Zebrafish
cell cycle	GO:0007049	93	0.025
cellular biosynthetic process	GO:0044249	286	0.025	Zebrafish
water homeostasis	GO:0030104	4	0.025
calcium mediated signaling	GO:0019722	2	0.025
positive regulation of metabolic process	GO:0009893	108	0.024	Zebrafish
ear development	GO:0043583	127	0.024
response to carbohydrate	GO:0009743	3	0.024
response to vitamin	GO:0033273	3	0.024
adult behavior	GO:0030534	2	0.024
peptidyl serine modification	GO:0018209	2	0.024
organic substance biosynthetic process	GO:1901576	289	0.024	Zebrafish
regulation of metabolic process	GO:0019222	359	0.024	Zebrafish
visual perception	GO:0007601	17	0.024
regulation of response to stimulus	GO:0048583	269	0.023
nitrogen compound metabolic process	GO:0006807	319	0.023	Zebrafish
regulation of skeletal muscle tissue development	GO:0048641	4	0.023
ovulation cycle process	GO:0022602	2	0.023
spermatid development	GO:0007286	2	0.022
sensory organ morphogenesis	GO:0090596	200	0.022
glial cell differentiation	GO:0010001	42	0.022
sensory perception of light stimulus	GO:0050953	19	0.022
response to glucose	GO:0009749	3	0.022
regulation of gtpase activity	GO:0043087	2	0.022
regulation of biosynthetic process	GO:0009889	250	0.022	Zebrafish
astrocyte differentiation	GO:0048708	1	0.022
positive regulation of cytoskeleton organization	GO:0051495	3	0.022
regulation of macromolecule biosynthetic process	GO:0010556	225	0.022	Zebrafish
inositol lipid mediated signaling	GO:0048017	2	0.022
hormone secretion	GO:0046879	2	0.022
protein metabolic process	GO:0019538	183	0.021
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.021
tissue remodeling	GO:0048771	4	0.021
regulation of neurotransmitter transport	GO:0051588	1	0.021
lipid catabolic process	GO:0016042	4	0.021
cellular protein modification process	GO:0006464	100	0.021
cellular macromolecule biosynthetic process	GO:0034645	224	0.021	Zebrafish
positive regulation of cellular metabolic process	GO:0031325	94	0.021	Zebrafish
positive regulation of secretion by cell	GO:1903532	1	0.021
regulation of cellular amine metabolic process	GO:0033238	0	0.021
phosphatidylinositol mediated signaling	GO:0048015	2	0.021
biosynthetic process	GO:0009058	294	0.021	Zebrafish
endocrine hormone secretion	GO:0060986	2	0.021
inorganic anion transport	GO:0015698	25	0.020
fatty acid elongation unsaturated fatty acid	GO:0019368	1	0.020
positive regulation of cellular amine metabolic process	GO:0033240	0	0.020
positive regulation of lipid metabolic process	GO:0045834	1	0.020
inorganic ion transmembrane transport	GO:0098660	57	0.020
locomotor rhythm	GO:0045475	3	0.019
glial cell development	GO:0021782	20	0.019
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.019	Zebrafish
response to abiotic stimulus	GO:0009628	122	0.019
regulation of cellular ketone metabolic process	GO:0010565	7	0.019
response to chemical	GO:0042221	320	0.019
brain development	GO:0007420	293	0.019
organic hydroxy compound transport	GO:0015850	14	0.019
mesenchyme development	GO:0060485	127	0.019
regulation of signal transduction	GO:0009966	225	0.019
peripheral nervous system neuron development	GO:0048935	22	0.019
homeostatic process	GO:0042592	142	0.019
monocarboxylic acid catabolic process	GO:0072329	3	0.019
enzyme linked receptor protein signaling pathway	GO:0007167	106	0.019
regulation of cell motility	GO:2000145	46	0.018
organic acid metabolic process	GO:0006082	31	0.018
phosphate containing compound metabolic process	GO:0006796	108	0.018
macromolecule localization	GO:0033036	54	0.018
regulation of macromolecule metabolic process	GO:0060255	317	0.018	Zebrafish
protein homooligomerization	GO:0051260	3	0.018
ammonium transport	GO:0015696	6	0.018
regulation of nucleic acid templated transcription	GO:1903506	213	0.018	Zebrafish
synaptic transmission	GO:0007268	35	0.018
nucleic acid templated transcription	GO:0097659	181	0.017	Zebrafish
regulation of sequestering of calcium ion	GO:0051282	4	0.017
meiotic cell cycle process	GO:1903046	3	0.017
nephron epithelium development	GO:0072009	16	0.017
growth	GO:0040007	174	0.017
regulation of growth rate	GO:0040009	1	0.017
negative regulation of dna replication	GO:0008156	2	0.017
regulation of nucleoside metabolic process	GO:0009118	2	0.017
cellular ketone metabolic process	GO:0042180	11	0.017
fatty acid catabolic process	GO:0009062	1	0.017
positive regulation of stem cell proliferation	GO:2000648	1	0.017
oxoacid metabolic process	GO:0043436	31	0.017
nucleic acid metabolic process	GO:0090304	244	0.017	Zebrafish
vasculature development	GO:0001944	278	0.017
regulation of neurotransmitter secretion	GO:0046928	1	0.016
stem cell differentiation	GO:0048863	117	0.016
chordate embryonic development	GO:0043009	271	0.016
synaptic growth at neuromuscular junction	GO:0051124	2	0.016
cell morphogenesis	GO:0000902	289	0.016
morphogenesis of an epithelial fold	GO:0060571	1	0.016
response to monosaccharide	GO:0034284	3	0.016
regulation of multicellular organismal development	GO:2000026	223	0.016
stem cell maintenance	GO:0019827	4	0.016
regulation of signaling	GO:0023051	235	0.016
response to hexose	GO:0009746	3	0.016
compound eye development	GO:0048749	2	0.015
organic acid catabolic process	GO:0016054	3	0.015
negative regulation of growth rate	GO:0045967	1	0.015
cell cell signaling	GO:0007267	52	0.015
cellular response to organic cyclic compound	GO:0071407	38	0.015
cytoskeleton organization	GO:0007010	96	0.015
hard palate development	GO:0060022	4	0.015
regulation of cellular biosynthetic process	GO:0031326	245	0.015	Zebrafish
ventral spinal cord interneuron fate commitment	GO:0060579	3	0.015
cell morphogenesis involved in differentiation	GO:0000904	195	0.015
regulation of cellular amino acid metabolic process	GO:0006521	0	0.015
positive regulation of cyclic nucleotide metabolic process	GO:0030801	8	0.015
small molecule metabolic process	GO:0044281	77	0.015
regulation of cell projection organization	GO:0031344	44	0.015
single organism biosynthetic process	GO:0044711	71	0.015
regulation of rna metabolic process	GO:0051252	224	0.015	Zebrafish
response to hormone	GO:0009725	48	0.015
mitochondrion organization	GO:0007005	4	0.015
regulation of calcium ion transport	GO:0051924	2	0.014
protein complex subunit organization	GO:0071822	46	0.014
spermatid differentiation	GO:0048515	2	0.014
peripheral nervous system development	GO:0007422	55	0.014
regulation of purine nucleotide metabolic process	GO:1900542	17	0.014
immune system process	GO:0002376	241	0.014
urogenital system development	GO:0001655	97	0.014
gtp catabolic process	GO:0006184	2	0.014
neuropeptide signaling pathway	GO:0007218	11	0.014
regulation of dna replication	GO:0006275	3	0.014
organic substance transport	GO:0071702	58	0.014
otolith development	GO:0048840	32	0.014
regulation of purine nucleotide catabolic process	GO:0033121	2	0.014
response to food	GO:0032094	1	0.014
ovulation cycle	GO:0042698	2	0.014
establishment of localization in cell	GO:0051649	77	0.014
regulation of erk1 and erk2 cascade	GO:0070372	4	0.014
muscle structure development	GO:0061061	196	0.014
cognition	GO:0050890	1	0.014
positive regulation of neural precursor cell proliferation	GO:2000179	1	0.014
regulation of nitrogen compound metabolic process	GO:0051171	251	0.014	Zebrafish
phosphorus metabolic process	GO:0006793	109	0.014
long chain fatty acid biosynthetic process	GO:0042759	1	0.013
peripheral nervous system neuron differentiation	GO:0048934	28	0.013
positive regulation of macromolecule metabolic process	GO:0010604	93	0.013	Zebrafish
phosphatidylinositol 3 kinase signaling	GO:0014065	2	0.013
developmental growth	GO:0048589	166	0.013
atp catabolic process	GO:0006200	4	0.013
axon ensheathment in central nervous system	GO:0032291	2	0.013
regulation of cellular protein metabolic process	GO:0032268	52	0.013
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	2	0.013
regulation of intracellular signal transduction	GO:1902531	57	0.013
striated muscle tissue development	GO:0014706	110	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	57	0.013	Zebrafish
response to external biotic stimulus	GO:0043207	97	0.013
fatty acid beta oxidation	GO:0006635	1	0.012
regulation of localization	GO:0032879	104	0.012
cyclic nucleotide biosynthetic process	GO:0009190	18	0.012
negative regulation of kinase activity	GO:0033673	4	0.012
gland development	GO:0048732	143	0.012
lens fiber cell development	GO:0070307	3	0.012
small molecule catabolic process	GO:0044282	3	0.012
rna biosynthetic process	GO:0032774	181	0.012	Zebrafish
oligodendrocyte differentiation	GO:0048709	23	0.012
detection of chemical stimulus	GO:0009593	4	0.012
transmission of nerve impulse	GO:0019226	19	0.012
positive regulation of secretion	GO:0051047	1	0.012
negative regulation of cell migration	GO:0030336	17	0.012
regulation of reproductive process	GO:2000241	4	0.012
protein phosphorylation	GO:0006468	47	0.012
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	1	0.012
negative regulation of mapk cascade	GO:0043409	4	0.012
negative regulation of dna metabolic process	GO:0051053	4	0.012
neuron differentiation	GO:0030182	353	0.012
organic cyclic compound biosynthetic process	GO:1901362	223	0.012	Zebrafish
regulation of phosphorylation	GO:0042325	26	0.012
cellular response to drug	GO:0035690	1	0.012
regulation of nucleotide metabolic process	GO:0006140	17	0.012
negative regulation of protein phosphorylation	GO:0001933	4	0.012
cellular lipid catabolic process	GO:0044242	3	0.012
regulation of synaptic plasticity	GO:0048167	1	0.011
response to radiation	GO:0009314	51	0.011
regulation of hormone secretion	GO:0046883	2	0.011
receptor internalization	GO:0031623	2	0.011
positive regulation of response to stimulus	GO:0048584	80	0.011
regulation of receptor activity	GO:0010469	2	0.011
cation transport	GO:0006812	81	0.011
embryonic limb morphogenesis	GO:0030326	2	0.011
oocyte maturation	GO:0001556	4	0.011
gliogenesis	GO:0042063	45	0.011
negative regulation of striated muscle tissue development	GO:0045843	2	0.011
positive regulation of cell communication	GO:0010647	56	0.011
erk1 and erk2 cascade	GO:0070371	4	0.011
carboxylic acid transport	GO:0046942	8	0.011
macromolecule biosynthetic process	GO:0009059	227	0.011	Zebrafish
peptidyl lysine acetylation	GO:0018394	2	0.011
regulation of organelle organization	GO:0033043	29	0.011
peptide metabolic process	GO:0006518	1	0.011
hormone biosynthetic process	GO:0042446	3	0.011
sensory perception	GO:0007600	39	0.011
response to amino acid	GO:0043200	2	0.011
germ line stem cell maintenance	GO:0030718	2	0.011
death	GO:0016265	121	0.011
regulation of transport	GO:0051049	45	0.011
regulation of tissue remodeling	GO:0034103	2	0.011
regulation of protein phosphorylation	GO:0001932	18	0.011
renal system process	GO:0003014	14	0.011
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	42	0.010
camera type eye morphogenesis	GO:0048593	108	0.010
anterior posterior pattern specification	GO:0009952	152	0.010
response to bacterium	GO:0009617	58	0.010
negative regulation of muscle tissue development	GO:1901862	2	0.010
glial cell proliferation	GO:0014009	4	0.010
regulation of cell cycle	GO:0051726	52	0.010
fatty acid oxidation	GO:0019395	1	0.010

kiss1ra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.025

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