Danio rerio

0 known processes

guk1

guanylate kinase 1

(Aliases: zgc:73128,zgc:73217,MGC73128)

guk1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory organ developmentGO:00074233930.644
eye developmentGO:00016542770.347
retina development in camera type eyeGO:00600411460.346
sensory organ morphogenesisGO:00905962000.333
lateral line system developmentGO:0048925760.258
sensory system developmentGO:0048880760.254
cellular nitrogen compound metabolic processGO:00346412900.252
generation of neuronsGO:00486993850.246
cellular component movementGO:00069283350.239
axon ensheathment in central nervous systemGO:003229120.231
digestive system developmentGO:00551232890.207
camera type eye developmentGO:00430102220.206
central nervous system developmentGO:00074173870.198
photoreceptor cell fate commitmentGO:004655210.195
sensory perception of chemical stimulusGO:000760630.195
blood vessel developmentGO:00015682460.183
ear developmentGO:00435831270.166
eye morphogenesisGO:00485921440.155
small molecule metabolic processGO:0044281770.154
cellular macromolecule metabolic processGO:00442603910.151
localization of cellGO:00516742440.149
regulation of smoothened signaling pathwayGO:0008589180.147
nitrogen compound metabolic processGO:00068073190.133
embryo development ending in birth or egg hatchingGO:00097922710.133
embryonic organ developmentGO:00485683810.132
cellular aromatic compound metabolic processGO:00067252950.127
tube morphogenesisGO:00352393490.123
camera type eye morphogenesisGO:00485931080.122
locomotionGO:00400113130.119
heterocycle metabolic processGO:00464832900.119
cortical cytoskeleton organizationGO:003086510.119
organic cyclic compound metabolic processGO:19013603010.118
posterior lateral line developmentGO:0048916380.116
inner ear morphogenesisGO:0042472630.110
neuron differentiationGO:00301823530.110
embryonic organ morphogenesisGO:00485622740.096
cell motilityGO:00488702440.094
signal transductionGO:00071654550.093
lateral line developmentGO:0048882660.086
cortical actin cytoskeleton organizationGO:003086610.085
convergent extensionGO:00600261180.085
gene expressionGO:00104672520.085
ear morphogenesisGO:0042471640.084
glial cell differentiationGO:0010001420.083
guanosine containing compound metabolic processGO:190106840.082
eye photoreceptor cell differentiationGO:0001754450.080
lateral line ganglion developmentGO:004889020.080
regulation of metabolic processGO:00192223590.078
morphogenesis of an epitheliumGO:00020093330.076
cell fate commitmentGO:0045165990.075
neuron developmentGO:00486662620.073
cellular nitrogen compound biosynthetic processGO:00442712180.073
calcium mediated signalingGO:001972220.073
inner ear developmentGO:00488391260.072
cellular response to radiationGO:007147840.072
head developmentGO:00603223030.071
g protein coupled receptor signaling pathwayGO:0007186740.071
retina morphogenesis in camera type eyeGO:0060042790.071
ameboidal type cell migrationGO:00016671430.069
chemosensory behaviorGO:000763510.069
cell migrationGO:00164772370.069
neuronal action potentialGO:0019228180.069
cellular component morphogenesisGO:00329893360.069
agingGO:000756820.068
nucleobase containing compound metabolic processGO:00061392740.068
vascular endothelial growth factor receptor signaling pathwayGO:0048010130.067
regulation of chemokine activityGO:190013630.067
guanosine containing compound catabolic processGO:190106920.066
angiogenesisGO:00015251580.066
larval developmentGO:000216420.065
gtp catabolic processGO:000618420.065
regulation of cellular macromolecule biosynthetic processGO:20001122220.063
light adaptionGO:003636710.063
epithelial cell differentiationGO:00308551160.062
regulation of gtp catabolic processGO:003312420.062
system processGO:00030081850.061
eye photoreceptor cell developmentGO:0042462300.060
vasculature developmentGO:00019442780.059
anterior posterior pattern specificationGO:00099521520.059
negative regulation of protein phosphorylationGO:000193340.058
apical junction assemblyGO:004329710.058
enzyme linked receptor protein signaling pathwayGO:00071671060.057
regulation of establishment of protein localizationGO:007020140.057
photoreceptor cell differentiationGO:0046530550.056
regulation of protein transportGO:005122330.056
gliogenesisGO:0042063450.055
heart developmentGO:00075073130.055
regulation of response to stimulusGO:00485832690.054
regulation of bindingGO:005109830.053
gtp metabolic processGO:004603940.053
regulation of primary metabolic processGO:00800903110.053
response to drugGO:004249330.052
regulation of nucleotide catabolic processGO:003081120.052
multicellular organism growthGO:003526440.052
brain developmentGO:00074202930.051
blood vessel morphogenesisGO:00485142160.051
transcription from rna polymerase ii promoterGO:0006366800.051
rho protein signal transductionGO:000726650.050
cell morphogenesisGO:00009022890.050
digestive tract morphogenesisGO:00485462310.050
regulation of cellular component organizationGO:0051128860.049
regulation of signal transductionGO:00099662250.049
phototransduction visible lightGO:000760320.048
neural retina developmentGO:0003407490.048
amine metabolic processGO:000930820.048
regionalizationGO:00030022740.048
response to abiotic stimulusGO:00096281220.047
nucleocytoplasmic transportGO:000691340.047
regulation of intracellular protein transportGO:003315730.047
semicircular canal developmentGO:0060872240.046
regulation of nitrogen compound metabolic processGO:00511712510.046
heterocycle biosynthetic processGO:00181302150.046
regulation of nucleobase containing compound metabolic processGO:00192192500.045
positive regulation of map kinase activityGO:004340630.045
negative regulation of cellular processGO:00485232830.045
single organism metabolic processGO:00447102170.045
gastrulationGO:00073692080.045
cellular amine metabolic processGO:004410620.044
transmission of nerve impulseGO:0019226190.044
detection of light stimulusGO:0009583120.044
response to external stimulusGO:00096052640.043
regulation of gtpase activityGO:004308720.043
photoreceptor cell developmentGO:0042461400.043
regulation of cellular metabolic processGO:00313233200.042
establishment of blood brain barrierGO:006085620.042
establishment of localizationGO:00512342440.042
regulation of protein bindingGO:004339330.042
chordate embryonic developmentGO:00430092710.042
regulation of cell communicationGO:00106462320.042
posterior lateral line system developmentGO:0048915460.041
hatching gland developmentGO:004878530.041
homeostatic processGO:00425921420.041
carboxylic acid metabolic processGO:0019752220.040
establishment of endothelial blood brain barrierGO:001404520.040
phosphorus metabolic processGO:00067931090.040
stem cell proliferationGO:007208940.040
mechanosensory lateral line system developmentGO:0048881490.040
negative regulation of biological processGO:00485193040.040
action potentialGO:0001508190.039
regulation of signalingGO:00230512350.039
response to chemicalGO:00422213200.039
myelin assemblyGO:003228810.039
regulation of reproductive processGO:200024140.038
phototransductionGO:000760220.038
response to uvGO:000941130.038
regulation of multicellular organism growthGO:004001440.038
organic substance biosynthetic processGO:19015762890.037
regulation of biological qualityGO:00650082630.037
establishment of endothelial barrierGO:006102830.037
regulation of nucleoside metabolic processGO:000911820.037
cellular amino acid metabolic processGO:000652070.037
activation of mapk activityGO:000018730.037
semicircular canal morphogenesisGO:0048752180.037
receptor recyclingGO:000188140.037
nuclear transportGO:005116940.036
regulation of cellular amine metabolic processGO:003323800.036
compound eye developmentGO:004874920.036
organelle organizationGO:00069962270.036
purine containing compound biosynthetic processGO:0072522200.036
cell projection morphogenesisGO:00488582440.036
glial cell developmentGO:0021782200.036
embryonic pattern specificationGO:0009880440.036
transcription dna templatedGO:00063511810.035
regulation of transcription from rna polymerase ii promoterGO:00063571140.034
stem cell divisionGO:001714510.034
regulation of membrane potentialGO:0042391230.034
positive regulation of cell cycleGO:004578730.034
response to light intensityGO:000964210.034
carbohydrate derivative metabolic processGO:1901135610.034
protein modification by small protein removalGO:007064610.033
gastrulation with mouth forming secondGO:0001702440.033
cell surface receptor signaling pathwayGO:00071663250.033
response to amineGO:001407510.033
regulation of protein modification by small protein conjugation or removalGO:190332030.032
cellular ketone metabolic processGO:0042180110.032
cell migration involved in gastrulationGO:0042074790.032
neurological system processGO:0050877620.032
detection of abiotic stimulusGO:0009582240.032
rna biosynthetic processGO:00327741810.032
meiotic nuclear divisionGO:000712640.032
developmental growthGO:00485891660.032
protein desumoylationGO:001692610.031
neuron fate determinationGO:004866420.031
organic cyclic compound biosynthetic processGO:19013622230.031
mesenchymal cell differentiationGO:0048762870.031
neuroblast proliferationGO:000740520.030
regulation of locomotionGO:0040012550.030
nucleic acid metabolic processGO:00903042440.030
cellular biosynthetic processGO:00442492860.030
retinal cell programmed cell deathGO:004666620.030
adult behaviorGO:003053420.030
regulation of purine nucleotide catabolic processGO:003312120.030
cellular response to chemical stimulusGO:00708871570.030
regulation of peptidyl tyrosine phosphorylationGO:005073010.030
central nervous system myelin formationGO:003228910.029
cognitionGO:005089010.029
phosphate containing compound metabolic processGO:00067961080.029
regulation of cellular ketone metabolic processGO:001056570.029
midbrain developmentGO:0030901280.029
negative regulation of signalingGO:0023057960.029
immune system processGO:00023762410.028
digestive tract developmentGO:00485652650.028
regulation of multicellular organismal developmentGO:20000262230.028
cellular macromolecule biosynthetic processGO:00346452240.028
regulation of developmental processGO:00507932470.028
growthGO:00400071740.028
specification of symmetryGO:00097992040.028
nucleobase containing compound biosynthetic processGO:00346542050.028
cellular localizationGO:0051641970.027
aromatic compound biosynthetic processGO:00194382170.027
regulation of macromolecule biosynthetic processGO:00105562250.027
regulation of cellular biosynthetic processGO:00313262450.027
regulation of nucleic acid templated transcriptionGO:19035062130.026
regulation of receptor recyclingGO:000191930.026
rna localizationGO:000640340.026
organonitrogen compound metabolic processGO:1901564740.026
negative regulation of signal transductionGO:0009968940.026
neural crest cell differentiationGO:0014033720.026
nuclear exportGO:005116810.026
nucleoside phosphate metabolic processGO:0006753280.026
lens fiber cell developmentGO:007030730.026
regulation of multicellular organismal processGO:00512392770.026
multicellular organismal signalingGO:0035637220.026
negative regulation of protein kinase activityGO:000646940.025
ras protein signal transductionGO:000726570.025
rna metabolic processGO:00160702190.025
biosynthetic processGO:00090582940.025
retina layer formationGO:0010842240.024
regulation of cellular amino acid metabolic processGO:000652100.024
positive regulation of transportGO:005105020.024
embryonic skeletal system morphogenesisGO:0048704930.024
regulation of rna biosynthetic processGO:20011412130.024
regulation of nucleocytoplasmic transportGO:004682220.023
macromolecule biosynthetic processGO:00090592270.023
somitogenesisGO:0001756870.023
regulation of synaptic growth at neuromuscular junctionGO:000858210.023
cell morphogenesis involved in neuron differentiationGO:00486671630.023
nucleic acid templated transcriptionGO:00976591810.023
negative regulation of defense responseGO:003134820.023
cellular response to decreased oxygen levelsGO:003629410.023
oxoacid metabolic processGO:0043436310.022
protein modification processGO:00362111000.022
negative regulation of cell cell adhesion mediated by cadherinGO:200004820.022
regulation of gene expressionGO:00104682650.022
phagocytosisGO:000690930.022
otic vesicle developmentGO:0071599420.021
regulation of chemotaxisGO:0050920180.021
taxisGO:00423301090.021
organic acid metabolic processGO:0006082310.021
inositol lipid mediated signalingGO:004801720.021
paraxial mesoderm morphogenesisGO:004834020.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.021
regulation of transcription dna templatedGO:00063552130.021
positive regulation of cellular metabolic processGO:0031325940.021
neuron projection extensionGO:1990138450.021
circadian rhythmGO:0007623190.021
developmental programmed cell deathGO:001062340.021
positive regulation of metabolic processGO:00098931080.020
neural crest cell developmentGO:0014032620.020
retinal cone cell developmentGO:004654980.020
regulation of macromolecule metabolic processGO:00602553170.020
meiotic cell cycle processGO:190304630.020
regulation of metal ion transportGO:001095940.020
establishment of protein localization to organelleGO:007259440.020
response to carbohydrateGO:000974330.019
single fertilizationGO:000733830.019
camera type eye photoreceptor cell differentiationGO:0060219190.019
regulation of cell differentiationGO:00455951420.019
skeletal system developmentGO:00015011810.019
protein metabolic processGO:00195381830.019
negative regulation of kinase activityGO:003367340.019
neuron neuron synaptic transmissionGO:000727010.019
regulation of rna metabolic processGO:00512522240.019
thermosensory behaviorGO:004004010.018
epibolyGO:0090504410.018
mesenchyme developmentGO:00604851270.018
endothelial cell developmentGO:0001885120.018
establishment or maintenance of polarity of embryonic epitheliumGO:001633220.018
regulation of growth rateGO:004000910.018
regulation of circadian rhythmGO:004275240.018
cell projection organizationGO:00300302840.018
maintenance of locationGO:005123540.018
mesenchymal cell developmentGO:0014031780.018
segmentationGO:0035282970.018
morphogenesis of an epithelial sheetGO:0002011490.018
regulation of localizationGO:00328791040.018
water homeostasisGO:003010440.018
embryonic retina morphogenesis in camera type eyeGO:0060059220.017
cellular response to oxygen levelsGO:007145310.017
rhombomere 6 developmentGO:002157240.017
regulation of transmembrane transporter activityGO:002289820.017
establishment of localization in cellGO:0051649770.017
cellular component assembly involved in morphogenesisGO:00109271070.017
response to foodGO:003209410.017
nucleobase containing small molecule metabolic processGO:0055086320.017
regulation of biosynthetic processGO:00098892500.017
cranial ganglion developmentGO:006155030.017
regulation of behaviorGO:0050795240.017
immune system developmentGO:00025201910.017
negative regulation of cell communicationGO:0010648960.017
behaviorGO:0007610740.017
nucleotide biosynthetic processGO:0009165210.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
response to stressGO:00069502630.016
small gtpase mediated signal transductionGO:000726480.016
membrane invaginationGO:001032410.016
cgmp metabolic processGO:004606870.016
organic substance transportGO:0071702580.016
regulation of cyclase activityGO:0031279120.016
hemopoiesisGO:00300971830.016
determination of bilateral symmetryGO:00098552040.016
endothelium developmentGO:0003158250.016
regulation of meiotic cell cycleGO:005144510.016
neural crest cell migrationGO:0001755420.016
multicellular organismal response to stressGO:003355520.016
positive regulation of macromolecule metabolic processGO:0010604930.016
intracellular signal transductionGO:0035556850.016
actin polymerization or depolymerizationGO:000815420.016
regulation of transportGO:0051049450.015
lipid storageGO:001991510.015
regulation of protein complex assemblyGO:004325430.015
embryonic heart tube morphogenesisGO:00031431080.015
rhombomere 5 developmentGO:002157140.015
cellular response to hypoxiaGO:007145610.015
positive regulation of synapse assemblyGO:005196510.015
embryonic skeletal system developmentGO:0048706970.015
regulation of anatomical structure morphogenesisGO:00226031300.015
anatomical structure homeostasisGO:0060249360.015
regulation of tube sizeGO:003515020.015
negative regulation of gene expressionGO:0010629650.015
multicellular organismal homeostasisGO:0048871290.015
tissue homeostasisGO:0001894250.015
locomotor rhythmGO:004547530.015
regulation of cell developmentGO:00602841000.015
protein polymerizationGO:005125840.015
embryonic viscerocranium morphogenesisGO:0048703520.015
rhodopsin mediated signaling pathwayGO:001605610.015
regulation of circadian sleep wake cycle sleepGO:004518710.015
negative regulation of macromolecule metabolic processGO:0010605760.015
response to woundingGO:00096111160.015
response to decreased oxygen levelsGO:0036293250.014
central nervous system myelinationGO:002201020.014
developmental growth involved in morphogenesisGO:0060560860.014
regulation of dna replicationGO:000627530.014
cellular component disassemblyGO:002241110.014
regulation of synaptic plasticityGO:004816710.014
regulation of ion transmembrane transporter activityGO:003241220.014
positive regulation of biosynthetic processGO:0009891680.014
embryonic cranial skeleton morphogenesisGO:0048701900.014
establishment of organelle localizationGO:0051656450.014
positive regulation of rna biosynthetic processGO:1902680570.014
single organism transportGO:00447652060.014
cellular response to organic substanceGO:00713101050.014
lamellipodium organizationGO:009758110.014
purine ribonucleotide metabolic processGO:0009150270.014
positive regulation of reproductive processGO:200024320.014
protein acylationGO:004354330.014
fertilizationGO:000956630.014
cellular response to light stimulusGO:007148240.014
neural tube developmentGO:0021915620.014
regulation of phosphate metabolic processGO:0019220430.014
cell growthGO:0016049570.014
response to amino acidGO:004320020.014
negative regulation of rna metabolic processGO:0051253480.014
embryonic axis specificationGO:0000578120.014
hematopoietic or lymphoid organ developmentGO:00485341910.013
response to monosaccharideGO:003428430.013
positive regulation of axon extension involved in axon guidanceGO:004884210.013
regulation of protein polymerizationGO:003227120.013
regulation of molecular functionGO:0065009700.013
carbohydrate homeostasisGO:003350010.013
positive regulation of rna metabolic processGO:0051254590.013
negative regulation of rna biosynthetic processGO:1902679450.013
ensheathment of neuronsGO:0007272180.013
determination of left right symmetryGO:00073681790.013
asymmetric protein localizationGO:000810560.013
retina homeostasisGO:0001895120.013
hormone secretionGO:004687920.013
positive regulation of cellular processGO:00485222010.013
single organism localizationGO:19025782250.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
sprouting angiogenesisGO:0002040530.013
ectodermal placode morphogenesisGO:0071697320.013
regulation of calcium ion transportGO:005192420.013
photoreceptor cell outer segment organizationGO:003584590.013
glucose homeostasisGO:004259310.013
negative regulation of retinal cell programmed cell deathGO:004667120.013
lipid catabolic processGO:001604240.013
cyclic nucleotide biosynthetic processGO:0009190180.013
response to alkaloidGO:004327920.013
cyclic nucleotide metabolic processGO:0009187180.013
protein secretionGO:000930610.013
regulation of sodium ion transportGO:000202820.012
catecholamine metabolic processGO:000658420.012
regulation of phosphorus metabolic processGO:0051174430.012
cellular catabolic processGO:0044248270.012
epithelial cell developmentGO:0002064420.012
ectodermal placode formationGO:0060788260.012
skin developmentGO:0043588540.012
pyruvate metabolic processGO:000609010.012
response to hexoseGO:000974630.012
axon developmentGO:00615641660.012
establishment of cell polarityGO:0030010180.012
dopamine metabolic processGO:004241720.012
response to light stimulusGO:0009416460.012
positive regulation of protein complex assemblyGO:003133420.012
phagocytosis engulfmentGO:000691110.012
regulation of inflammatory responseGO:005072720.012
transportGO:00068102200.012
regulation of synapse organizationGO:005080730.012
axon extension involved in axon guidanceGO:0048846100.012
hindbrain developmentGO:0030902910.012
organophosphate metabolic processGO:0019637370.012
chemotaxisGO:00069351040.012
cation transportGO:0006812810.012
detection of stimulusGO:0051606290.012
developmental pigmentationGO:0048066480.012
positive regulation of biological processGO:00485182530.012
axis specificationGO:0009798430.012
neuron projection morphogenesisGO:00488121610.012
epiboly involved in gastrulation with mouth forming secondGO:0055113350.012
olfactory lobe developmentGO:002198840.012
stem cell developmentGO:0048864820.012
diterpenoid metabolic processGO:0016101150.012
positive regulation of catabolic processGO:000989640.012
regulation of catalytic activityGO:0050790550.012
circadian regulation of gene expressionGO:003292280.012
positive regulation of cellular component biogenesisGO:004408930.011
regenerationGO:0031099910.011
regulation of cell motilityGO:2000145460.011
forebrain developmentGO:0030900960.011
gland developmentGO:00487321430.011
protein targeting to nucleusGO:004474430.011
cell part morphogenesisGO:00329902460.011
regulation of protein catabolic processGO:004217610.011
synaptic vesicle localizationGO:009747910.011
hormone transportGO:000991420.011
cellular transition metal ion homeostasisGO:004691630.011
midbrain hindbrain boundary developmentGO:0030917230.011
positive regulation of striated muscle tissue developmentGO:004584410.011
dorsal motor nucleus of vagus nerve developmentGO:002174440.011
neuromast primordium migrationGO:0048883120.011
posterior lateral line neuromast primordium migrationGO:0048920120.011
cell cycle arrestGO:000705010.011
nucleotide metabolic processGO:0009117280.011
positive regulation of nucleic acid templated transcriptionGO:1903508570.011
neuron projection regenerationGO:0031102160.011
protein complex disassemblyGO:004324110.011
regulation of sequestering of calcium ionGO:005128240.011
ectodermal placode developmentGO:0071696370.011
single organism organelle organizationGO:19025891990.011
regulation of cellular component movementGO:0051270550.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
auditory receptor cell fate determinationGO:004266820.011
positive regulation of cytoskeleton organizationGO:005149530.011
fatty acid transportGO:001590810.010
positive regulation of cell divisionGO:005178120.010
organelle localizationGO:0051640490.010
regulation of transporter activityGO:003240920.010
septum transversum developmentGO:000334340.010
negative regulation of nucleobase containing compound metabolic processGO:0045934590.010
convergent extension involved in gastrulationGO:0060027710.010
regulation of cell migrationGO:0030334400.010
tissue remodelingGO:004877140.010
epithelial tube morphogenesisGO:00605621480.010
regulation of protein metabolic processGO:0051246560.010
neuromast developmentGO:0048884460.010
pectoral fin morphogenesisGO:0035138290.010
positive regulation of nucleobase containing compound metabolic processGO:0045935690.010
actin filament polymerizationGO:003004120.010
atp catabolic processGO:000620040.010
single organism nuclear importGO:190259330.010
photoreceptor cell maintenanceGO:0045494110.010
regulation of cell activationGO:005086510.010
macromolecular complex disassemblyGO:003298410.010
cell projection assemblyGO:0030031640.010
cilium organizationGO:0044782710.010

guk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:561400.640
nervous system diseaseDOID:86300.640
eye and adnexa diseaseDOID:149200.640
disease of anatomical entityDOID:700.640
retinal degenerationDOID:846600.640
sensory system diseaseDOID:005015500.640
retinal diseaseDOID:567900.640
retinitis pigmentosaDOID:1058400.256
musculoskeletal system diseaseDOID:1700.022
disease of metabolismDOID:001466700.015
inherited metabolic disorderDOID:65500.011