Danio rerio

115 known processes

ocrl

oculocerebrorenal syndrome of Lowe

(Aliases: zgc:152864,wu:fi09g03)

ocrl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.763
neuron differentiationGO:00301823530.699
sensory organ developmentGO:00074233930.651
epithelial cell differentiationGO:00308551160.560
digestive system developmentGO:00551232890.537
regulation of response to stimulusGO:00485832690.498
negative regulation of tor signalingGO:003200720.435
embryonic organ developmentGO:00485683810.408
response to drugGO:004249330.403
generation of neuronsGO:00486993850.398
embryo development ending in birth or egg hatchingGO:00097922710.368
cell projection morphogenesisGO:00488582440.360
digestive tract developmentGO:00485652650.344
response to chemicalGO:00422213200.304
hormone biosynthetic processGO:004244630.276
photoreceptor cell differentiationGO:0046530550.261
cognitionGO:005089010.237
mononuclear cell proliferationGO:003294310.235
chordate embryonic developmentGO:00430092710.231
hormone metabolic processGO:0042445190.202
ear developmentGO:00435831270.201
establishment of localizationGO:00512342440.200
regulation of biological qualityGO:00650082630.188
pigmentationGO:0043473850.187
multi organism processGO:00517041340.182
embryonic organ morphogenesisGO:00485622740.180
head developmentGO:00603223030.169
multicellular organismal response to stressGO:003355520.167
eye photoreceptor cell differentiationGO:0001754450.166
nitrogen compound metabolic processGO:00068073190.164
synaptic transmission cholinergicGO:000727140.163
agingGO:000756820.163
developmental growthGO:00485891660.162
single organism localizationGO:19025782250.162
muscle structure developmentGO:00610611960.159
sensory organ morphogenesisGO:00905962000.153
cellular nitrogen compound metabolic processGO:00346412900.151
organic cyclic compound metabolic processGO:19013603010.150
lipid biosynthetic processGO:0008610220.146
regulation of cellular amine metabolic processGO:003323800.144
lateral line system developmentGO:0048925760.143
regulation of cell proliferationGO:0042127370.143
response to stressGO:00069502630.143
nucleic acid metabolic processGO:00903042440.142
pronephros developmentGO:0048793690.138
biosynthetic processGO:00090582940.137
steroid biosynthetic processGO:000669450.135
immune system processGO:00023762410.135
regulation of hormone metabolic processGO:003235060.131
inner ear developmentGO:00488391260.128
lipid metabolic processGO:0006629520.125
kidney developmentGO:0001822920.124
growthGO:00400071740.118
cellular macromolecule metabolic processGO:00442603910.116
regulation of neurogenesisGO:0050767870.113
cellular component biogenesisGO:00440851780.113
neural crest cell developmentGO:0014032620.111
cellular hormone metabolic processGO:0034754190.111
muscle tissue developmentGO:00605371100.110
cellular protein metabolic processGO:00442671290.109
estrogen metabolic processGO:000821020.104
eye morphogenesisGO:00485921440.103
wound healingGO:0042060900.099
response to external stimulusGO:00096052640.098
organic acid metabolic processGO:0006082310.098
determination of left right symmetryGO:00073681790.098
cell morphogenesis involved in neuron differentiationGO:00486671630.098
regulation of developmental processGO:00507932470.097
negative regulation of protein kinase b signalingGO:005189820.096
response to woundingGO:00096111160.095
fin developmentGO:0033333770.095
transportGO:00068102200.095
pancreas developmentGO:0031016840.092
terpenoid metabolic processGO:0006721150.092
brain developmentGO:00074202930.091
regulation of cellular ketone metabolic processGO:001056570.090
regulation of cell developmentGO:00602841000.089
organic substance biosynthetic processGO:19015762890.088
camera type eye developmentGO:00430102220.088
cellular biosynthetic processGO:00442492860.085
small molecule metabolic processGO:0044281770.084
multicellular organismal signalingGO:0035637220.084
cellular ketone metabolic processGO:0042180110.083
response to metal ionGO:0010038340.083
embryonic skeletal system morphogenesisGO:0048704930.082
neuromast developmentGO:0048884460.082
appendage morphogenesisGO:0035107560.082
system processGO:00030081850.080
regulation of stem cell differentiationGO:200073640.079
regenerationGO:0031099910.076
protein metabolic processGO:00195381830.076
cellular respirationGO:004533330.075
tor signalingGO:003192970.075
regulation of multicellular organismal developmentGO:20000262230.074
regulation of metabolic processGO:00192223590.073
leukocyte proliferationGO:007066110.073
regulation of gene expressionGO:00104682650.072
stem cell developmentGO:0048864820.070
fin regenerationGO:0031101510.070
response to corticosteroidGO:003196010.069
potassium ion transportGO:0006813100.069
nucleoside monophosphate catabolic processGO:000912540.069
regulation of signal transductionGO:00099662250.068
neuron developmentGO:00486662620.067
intracellular signal transductionGO:0035556850.066
regulation of cell communicationGO:00106462320.066
regulation of stem cell proliferationGO:007209120.066
cell projection organizationGO:00300302840.065
regulation of cell differentiationGO:00455951420.064
cellular aromatic compound metabolic processGO:00067252950.064
single organism metabolic processGO:00447102170.064
signal transductionGO:00071654550.063
transmembrane transportGO:00550851200.063
single organism reproductive processGO:0044702400.062
reproductionGO:0000003400.062
neural crest cell differentiationGO:0014033720.061
mesenchyme developmentGO:00604851270.061
positive regulation of cell activationGO:005086710.061
central nervous system developmentGO:00074173870.061
gene expressionGO:00104672520.060
viral processGO:001603210.060
oxoacid metabolic processGO:0043436310.059
striated muscle tissue developmentGO:00147061100.059
negative regulation of ras protein signal transductionGO:004658010.059
cellular lipid metabolic processGO:0044255360.059
heterocycle metabolic processGO:00464832900.058
cellular amine metabolic processGO:004410620.058
cell substrate adhesionGO:003158940.058
ribonucleoside monophosphate catabolic processGO:000915840.057
skeletal system developmentGO:00015011810.057
nucleobase containing compound metabolic processGO:00061392740.055
negative regulation of biological processGO:00485193040.055
regulation of hormone levelsGO:0010817210.054
cellular aldehyde metabolic processGO:000608140.054
cellular response to chemical stimulusGO:00708871570.054
medial fin developmentGO:0033338160.053
behaviorGO:0007610740.053
carboxylic acid metabolic processGO:0019752220.052
heart morphogenesisGO:00030071560.052
amine metabolic processGO:000930820.052
regulation of protein ubiquitinationGO:003139630.052
diterpenoid biosynthetic processGO:001610270.051
organelle organizationGO:00069962270.051
eye developmentGO:00016542770.051
establishment of protein localization to organelleGO:007259440.051
response to glucocorticoidGO:005138410.051
stem cell differentiationGO:00488631170.051
fin morphogenesisGO:0033334530.051
cellular component morphogenesisGO:00329893360.050
regulation of signalingGO:00230512350.050
cell part morphogenesisGO:00329902460.050
diterpenoid metabolic processGO:0016101150.049
regulation of multicellular organismal processGO:00512392770.048
tissue regenerationGO:0042246740.048
regulation of cellular amino acid metabolic processGO:000652100.048
action potentialGO:0001508190.048
regulation of macromolecule metabolic processGO:00602553170.048
heart loopingGO:0001947940.048
isoprenoid biosynthetic processGO:000829970.047
phosphatidylinositol 3 kinase signalingGO:001406520.047
epithelial structure maintenanceGO:001066980.046
cellular component assemblyGO:00226071700.046
positive regulation of carbohydrate metabolic processGO:004591310.046
regulation of peptidyl tyrosine phosphorylationGO:005073010.046
otolith developmentGO:0048840320.046
axon developmentGO:00615641660.045
axon guidanceGO:0007411860.045
response to carbohydrateGO:000974330.045
hemopoiesisGO:00300971830.045
ion transmembrane transportGO:0034220910.045
regulation of protein catabolic processGO:004217610.045
homeostatic processGO:00425921420.045
lymphocyte proliferationGO:004665110.044
negative regulation of response to stimulusGO:00485851040.044
cell morphogenesis involved in differentiationGO:00009041950.044
response to oxygen containing compoundGO:1901700550.044
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.043
neurological system processGO:0050877620.043
regulation of dendrite developmentGO:005077330.043
maintenance of gastrointestinal epitheliumGO:003027770.043
positive regulation of stress activated mapk cascadeGO:003287430.043
respiratory electron transport chainGO:002290420.042
oxidation reduction processGO:0055114410.042
positive regulation of cellular amine metabolic processGO:003324000.042
vitamin metabolic processGO:0006766110.041
collagen metabolic processGO:003296320.041
embryonic skeletal joint developmentGO:007249830.041
response to abiotic stimulusGO:00096281220.041
appendage developmentGO:0048736800.041
embryonic appendage morphogenesisGO:0035113300.041
homeostasis of number of cellsGO:0048872620.041
negative regulation of small gtpase mediated signal transductionGO:005105810.040
peripheral nervous system developmentGO:0007422550.040
hematopoietic or lymphoid organ developmentGO:00485341910.040
cation transportGO:0006812810.040
regulation of circadian rhythmGO:004275240.040
mesenchymal cell differentiationGO:0048762870.040
carboxylic acid biosynthetic processGO:0046394120.040
renal system developmentGO:0072001940.039
purine ribonucleoside monophosphate catabolic processGO:000916940.039
exocrine pancreas developmentGO:0031017280.038
myelinationGO:0042552180.038
startle responseGO:000196440.038
regulation of photoreceptor cell differentiationGO:004653220.038
stem cell maintenanceGO:001982740.038
regulation of protein kinase b signalingGO:005189680.038
protein localization to nucleusGO:003450430.038
regulation of nitrogen compound metabolic processGO:00511712510.038
protein kinase b signalingGO:004349190.038
regulation of intracellular signal transductionGO:1902531570.038
single organism nuclear importGO:190259330.037
protein stabilizationGO:005082120.037
sensory system developmentGO:0048880760.037
regulation of nucleobase containing compound metabolic processGO:00192192500.037
determination of bilateral symmetryGO:00098552040.037
microtubule organizing center organizationGO:003102310.037
positive regulation of cellular amino acid metabolic processGO:004576400.037
androgen metabolic processGO:000820920.037
phosphate containing compound metabolic processGO:00067961080.036
regulation of nervous system developmentGO:0051960900.036
multi organism reproductive processGO:0044703360.035
regulation of autophagyGO:001050630.035
positive regulation of cell communicationGO:0010647560.035
negative regulation of intracellular signal transductionGO:1902532220.035
stem cell proliferationGO:007208940.035
negative regulation of cellular processGO:00485232830.034
morphogenesis of an epitheliumGO:00020093330.034
positive regulation of cellular processGO:00485222010.034
cellular response to nutrient levelsGO:003166920.034
neuron neuron synaptic transmissionGO:000727010.034
epithelial cell developmentGO:0002064420.034
skeletal muscle tissue developmentGO:0007519670.033
extracellular matrix organizationGO:0030198270.033
cell cycle g1 s phase transitionGO:004484310.033
multicellular organismal macromolecule metabolic processGO:004425920.033
immunoglobulin mediated immune responseGO:001606430.033
purine nucleoside monophosphate catabolic processGO:000912840.032
modification dependent macromolecule catabolic processGO:004363230.032
urogenital system developmentGO:0001655970.032
response to monosaccharideGO:003428430.032
exocrine system developmentGO:0035272280.032
embryonic pectoral fin morphogenesisGO:0035118240.032
cation transmembrane transportGO:0098655650.031
regulation of transcription from rna polymerase ii promoterGO:00063571140.031
macromolecule modificationGO:00434121110.031
microtubule based processGO:0007017600.031
regulation of protein modification by small protein conjugation or removalGO:190332030.031
circulatory system processGO:0003013870.031
transcription from rna polymerase ii promoterGO:0006366800.031
regulation of neural precursor cell proliferationGO:200017730.031
centrosome organizationGO:005129710.031
multicellular organism growthGO:003526440.031
negative regulation of protein transportGO:005122430.031
endocrine pancreas developmentGO:0031018270.030
single organism transportGO:00447652060.030
response to lipidGO:0033993600.030
modification dependent protein catabolic processGO:001994130.030
organelle assemblyGO:00709251100.030
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.030
positive regulation of epithelial cell proliferationGO:005067910.030
inorganic cation transmembrane transportGO:0098662500.029
chemotaxisGO:00069351040.029
nucleic acid templated transcriptionGO:00976591810.029
steroid metabolic processGO:000820270.029
cellular protein catabolic processGO:004425740.029
multicellular organismal metabolic processGO:004423620.029
response to organic substanceGO:00100331530.029
tube morphogenesisGO:00352393490.029
intestinal epithelial cell differentiationGO:006057530.029
multi organism cellular processGO:004476420.028
synaptic growth at neuromuscular junctionGO:005112420.028
cranial nerve developmentGO:0021545420.028
determination of heart left right asymmetryGO:00613711170.028
regulation of multicellular organism growthGO:004001440.028
protein localization to plasma membraneGO:007265910.028
regulation of protein transportGO:005122330.028
ion transportGO:00068111140.028
cell cell signalingGO:0007267520.028
rna biosynthetic processGO:00327741810.028
deathGO:00162651210.027
transmission of nerve impulseGO:0019226190.027
generation of precursor metabolites and energyGO:000609150.027
retina development in camera type eyeGO:00600411460.027
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.027
neuron projection developmentGO:00311751800.027
immune system developmentGO:00025201910.027
posterior lateral line system developmentGO:0048915460.027
locomotionGO:00400113130.027
cellular component movementGO:00069283350.027
negative regulation of developmental processGO:0051093650.027
nucleocytoplasmic transportGO:000691340.027
mitotic cell cycle processGO:1903047480.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
positive regulation of catabolic processGO:000989640.026
embryonic hemopoiesisGO:0035162530.026
axonogenesisGO:00074091520.026
negative regulation of cell differentiationGO:0045596460.026
positive regulation of cell cycleGO:004578730.026
single organism organelle organizationGO:19025891990.026
regulation of rna biosynthetic processGO:20011412130.026
circadian rhythmGO:0007623190.026
cell deathGO:00082191210.026
organic cyclic compound biosynthetic processGO:19013622230.026
protein import into nucleusGO:000660630.026
cellular protein modification processGO:00064641000.025
adult behaviorGO:003053420.025
posterior lateral line nerve glial cell developmentGO:004894150.025
centrosome cycleGO:000709810.025
alpha amino acid metabolic processGO:190160530.025
forebrain developmentGO:0030900960.025
regulation of neuron differentiationGO:0045664560.025
membrane repolarizationGO:008600920.024
protein importGO:001703830.024
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.024
energy reserve metabolic processGO:000611220.024
positive regulation of rna metabolic processGO:0051254590.024
positive regulation of protein kinase b signalingGO:005189710.024
cellular component disassemblyGO:002241110.024
cytoskeleton organizationGO:0007010960.024
meiotic nuclear divisionGO:000712640.024
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.024
lateral line developmentGO:0048882660.024
regulation of ventricular cardiac muscle cell membrane repolarizationGO:006030710.024
gene silencing by rnaGO:003104740.024
negative regulation of intracellular protein transportGO:009031730.024
nuclear importGO:005117030.024
cellular amino acid metabolic processGO:000652070.023
toxin transportGO:190199820.023
embryonic heart tube morphogenesisGO:00031431080.023
cellular response to organic substanceGO:00713101050.023
bicarbonate transportGO:001570140.023
response to external biotic stimulusGO:0043207970.023
regulation of erk1 and erk2 cascadeGO:007037240.023
glial cell proliferationGO:001400940.023
regulation of cell activationGO:005086510.023
positive regulation of ras protein signal transductionGO:004657910.023
negative regulation of cytoplasmic transportGO:190365020.023
gtp metabolic processGO:004603940.023
rna metabolic processGO:00160702190.022
transcription elongation from rna polymerase ii promoterGO:000636830.022
regulation of glucose transportGO:001082710.022
electron transport chainGO:002290020.022
positive regulation of map kinase activityGO:004340630.022
neuronal action potentialGO:0019228180.022
mechanosensory lateral line system developmentGO:0048881490.022
modulation by virus of host morphology or physiologyGO:001904810.022
establishment of protein localization to plasma membraneGO:009000210.022
regulation of anatomical structure morphogenesisGO:00226031300.022
proteasomal protein catabolic processGO:001049820.022
caudal fin developmentGO:003333690.022
negative regulation of signal transductionGO:0009968940.022
digestive tract morphogenesisGO:00485462310.022
regulation of neurological system processGO:003164420.022
response to hexoseGO:000974630.022
response to ketoneGO:190165410.021
aromatic compound biosynthetic processGO:00194382170.021
positive regulation of small gtpase mediated signal transductionGO:005105710.021
positive regulation of neural precursor cell proliferationGO:200017910.021
negative regulation of nitrogen compound metabolic processGO:0051172590.021
protein dephosphorylationGO:000647030.021
intestinal epithelial structure maintenanceGO:006072970.021
macromolecule biosynthetic processGO:00090592270.021
phosphatidylinositol mediated signalingGO:004801520.021
actomyosin structure organizationGO:0031032530.021
cell proliferationGO:0008283800.021
glial cell differentiationGO:0010001420.021
negative regulation of neural precursor cell proliferationGO:200017810.021
regulation of circadian sleep wake cycle sleepGO:004518710.020
positive regulation of myeloid cell differentiationGO:004563920.020
pronuclear migrationGO:003504610.020
apoptotic process involved in developmentGO:190274220.020
positive regulation of cell adhesionGO:004578510.020
regulation of collagen metabolic processGO:001071220.020
muscle cell developmentGO:00550011150.020
response to retinoic acidGO:003252660.020
positive regulation of chromosome organizationGO:200125210.020
isoprenoid metabolic processGO:0006720150.020
negative regulation of gene expressionGO:0010629650.019
apoptotic processGO:00069151160.019
response to biotic stimulusGO:0009607970.019
regulation of primary metabolic processGO:00800903110.019
liver developmentGO:0001889960.019
cation homeostasisGO:0055080330.019
atp synthesis coupled electron transportGO:004277310.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.019
protein secretionGO:000930610.019
positive regulation of biological processGO:00485182530.019
cellular response to starvationGO:000926710.019
developmental maturationGO:0021700340.019
carbohydrate biosynthetic processGO:001605110.019
ubiquitin dependent protein catabolic processGO:000651130.019
extrinsic apoptotic signaling pathwayGO:009719130.019
blood circulationGO:0008015870.019
regulation of neuronal synaptic plasticityGO:004816810.019
protein modification processGO:00362111000.019
regulation of rho protein signal transductionGO:003502320.019
regulation of rac protein signal transductionGO:003502010.019
peptide transportGO:001583310.019
regulation of dna templated transcription elongationGO:003278430.018
oocyte maturationGO:000155640.018
regulation of organ growthGO:004662030.018
membrane lipid metabolic processGO:0006643100.018
regulation of reproductive processGO:200024140.018
regulation of cell projection organizationGO:0031344440.018
regulation of epithelial cell proliferationGO:005067830.018
developmental growth involved in morphogenesisGO:0060560860.018
retinal metabolic processGO:004257430.018
response to inorganic substanceGO:0010035380.018
atp catabolic processGO:000620040.018
internal protein amino acid acetylationGO:000647520.018
protein targeting to nucleusGO:004474430.018
schwann cell developmentGO:001404490.018
medial fin morphogenesisGO:0035141140.018
multicellular organismal reproductive processGO:0048609350.018
columnar cuboidal epithelial cell differentiationGO:0002065380.018
regulation of catalytic activityGO:0050790550.018
regulation of cell shapeGO:000836010.018
catecholamine metabolic processGO:000658420.018
cell migrationGO:00164772370.018
positive regulation of cellular catabolic processGO:003133130.018
midbrain developmentGO:0030901280.018
negative regulation of gliogenesisGO:001401410.018
positive regulation of cell proliferationGO:0008284150.018
androgen biosynthetic processGO:000670210.017
skeletal muscle organ developmentGO:0060538780.017
regulation of protein import into nucleusGO:004230620.017
response to bacteriumGO:0009617580.017
protein polyubiquitinationGO:000020940.017
neuron projection guidanceGO:0097485860.017
response to endogenous stimulusGO:0009719830.017
circadian sleep wake cycle processGO:002241020.017
cell projection assemblyGO:0030031640.017
regulation of establishment of protein localizationGO:007020140.017
compound eye developmentGO:004874920.017
organism emergence from protective structureGO:007168440.017
camera type eye morphogenesisGO:00485931080.017
negative regulation of protein localization to nucleusGO:190018120.017
reactive oxygen species biosynthetic processGO:190340910.017
retinoic acid metabolic processGO:004257390.017
protein acetylationGO:000647320.017
glial cell migrationGO:000834730.017
regulation of nucleocytoplasmic transportGO:004682220.017
myelination in peripheral nervous systemGO:002201140.017
ras protein signal transductionGO:000726570.017
spindle assemblyGO:005122520.017
cell surface receptor signaling pathwayGO:00071663250.017
negative regulation of leukocyte differentiationGO:190210610.017
response to glucoseGO:000974930.017
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.017
maturation of ssu rrnaGO:003049010.016
embryonic heart tube developmentGO:00350501330.016
cellular response to external stimulusGO:007149620.016
taxisGO:00423301090.016
positive regulation of transportGO:005105020.016
single organism cellular localizationGO:1902580460.016
positive regulation of macromolecule metabolic processGO:0010604930.016
dna templated transcription elongationGO:000635430.016
monovalent inorganic cation transportGO:0015672420.016
brain morphogenesisGO:0048854180.016
positive regulation of neuron deathGO:190121610.016
negative regulation of cell migrationGO:0030336170.016
g1 s transition of mitotic cell cycleGO:000008210.016
negative regulation of synapse assemblyGO:005196420.016
sodium ion transmembrane transportGO:0035725210.016
metal ion transportGO:0030001580.016
positive regulation of cellular component biogenesisGO:004408930.016
neuromuscular synaptic transmissionGO:000727420.016
anatomical structure homeostasisGO:0060249360.016
epithelium migrationGO:0090132250.015
regulation of growth rateGO:004000910.015
glucose importGO:004632320.015
ear morphogenesisGO:0042471640.015
erk1 and erk2 cascadeGO:007037140.015
heart processGO:0003015710.015
thermosensory behaviorGO:004004010.015
response to topologically incorrect proteinGO:003596620.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
regulation of protein localization to nucleusGO:190018020.015
response to other organismGO:0051707970.015
centrosome duplicationGO:005129810.015
extracellular structure organizationGO:0043062270.015
organonitrogen compound metabolic processGO:1901564740.015
axon extensionGO:0048675450.015
metal ion homeostasisGO:0055065260.015
regulation of hormone secretionGO:004688320.015
positive regulation of cellular carbohydrate metabolic processGO:001067610.015
single organism biosynthetic processGO:0044711710.015
embryonic skeletal joint morphogenesisGO:006027230.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015

ocrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.045
disease of cellular proliferationDOID:1456600.036
inherited metabolic disorderDOID:65500.034
cancerDOID:16200.027
organ system cancerDOID:005068600.027
endocrine gland cancerDOID:17000.017