Danio rerio

0 known processes

itpr2

inositol 1,4,5-triphosphate receptor, type 2

(Aliases: si:dkey-196d8.1)

itpr2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
maintenance of locationGO:005123540.056
Fly
adult behaviorGO:003053420.049
Fly
larval developmentGO:000216420.045
cognitionGO:005089010.044
agingGO:000756820.042
regulation of cell shapeGO:000836010.039
regulation of multicellular organism growthGO:004001440.037
lipid storageGO:001991510.037
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.035
signal transductionGO:00071654550.034
Mouse Rat Fly
regulation of synaptic plasticityGO:004816710.033
cellular component movementGO:00069283350.033
modification dependent macromolecule catabolic processGO:004363230.033
multicellular organism growthGO:003526440.031
protein dephosphorylationGO:000647030.029
system processGO:00030081850.029
Fly
actin polymerization or depolymerizationGO:000815420.028
cellular protein catabolic processGO:004425740.028
regulation of synapse organizationGO:005080730.028
protein heterooligomerizationGO:005129110.027
regulation of synapse assemblyGO:005196330.027
release of sequestered calcium ion into cytosolGO:005120930.026
Fly
autophagyGO:000691440.026
regulation of biological qualityGO:00650082630.026
Fly
ubiquitin dependent protein catabolic processGO:000651130.026
organelle organizationGO:00069962270.025
Fly
positive regulation of transportGO:005105020.025
stem cell maintenanceGO:001982740.025
response to stressGO:00069502630.025
Rat Fly
organelle fusionGO:004828430.025
neuron differentiationGO:00301823530.025
gtp metabolic processGO:004603940.024
membrane fusionGO:006102520.024
lateral inhibitionGO:004633110.024
proteasomal protein catabolic processGO:001049820.024
lipid homeostasisGO:005508830.024
Fly
regulation of muscle contractionGO:000693730.023
regulation of nucleotide catabolic processGO:003081120.023
regulation of multicellular organismal processGO:00512392770.023
head developmentGO:00603223030.023
Fly
positive regulation of protein complex assemblyGO:003133420.023
gtp catabolic processGO:000618420.023
proteolysis involved in cellular protein catabolic processGO:005160330.023
action potentialGO:0001508190.023
cell morphogenesisGO:00009022890.023
cell migrationGO:00164772370.022
ion transmembrane transportGO:0034220910.022
Mouse Rat Fly
positive regulation of cell cycleGO:004578730.022
guanosine containing compound metabolic processGO:190106840.022
synaptic growth at neuromuscular junctionGO:005112420.022
nucleoside monophosphate catabolic processGO:000912540.022
nuclear transportGO:005116940.022
modification dependent protein catabolic processGO:001994130.021
guanosine containing compound catabolic processGO:190106920.021
regulation of circadian rhythmGO:004275240.021
purine nucleoside monophosphate catabolic processGO:000912840.021
embryonic organ morphogenesisGO:00485622740.021
meiotic cell cycle processGO:190304630.021
i kappab kinase nf kappab signalingGO:000724940.021
cell projection organizationGO:00300302840.021
nuclear migrationGO:000709730.021
microtubule organizing center organizationGO:003102310.021
rna localizationGO:000640340.021
response to chemicalGO:00422213200.021
Mouse Rat
regulation of reproductive processGO:200024140.021
vacuolar transportGO:000703420.021
positive regulation of cellular catabolic processGO:003133130.021
single organism membrane fusionGO:004480120.020
cellular component disassemblyGO:002241110.020
single organism metabolic processGO:00447102170.020
protein homooligomerizationGO:005126030.020
purine ribonucleoside monophosphate catabolic processGO:000916940.020
phagocytosisGO:000690930.020
negative regulation of sequestering of calcium ionGO:005128340.020
Fly
transportGO:00068102200.020
Mouse Rat Fly
meiotic nuclear divisionGO:000712640.020
negative regulation of protein phosphorylationGO:000193340.020
regulation of tube sizeGO:003515020.019
endosomal transportGO:001619720.019
regulation of rho protein signal transductionGO:003502320.019
regulation of developmental processGO:00507932470.019
generation of neuronsGO:00486993850.019
ribonucleoside monophosphate catabolic processGO:000915840.019
cellular component morphogenesisGO:00329893360.019
centrosome organizationGO:005129710.019
protein acetylationGO:000647320.019
regulation of i kappab kinase nf kappab signalingGO:004312240.019
regulation of cellular component organizationGO:0051128860.019
establishment of protein localization to organelleGO:007259440.019
regulation of nucleoside metabolic processGO:000911820.019
stem cell proliferationGO:007208940.019
cell projection morphogenesisGO:00488582440.019
internal peptidyl lysine acetylationGO:001839320.019
amine metabolic processGO:000930820.019
establishment of localizationGO:00512342440.019
Mouse Rat Fly
stem cell divisionGO:001714510.019
actin filament based movementGO:003004810.018
regulation of cell activationGO:005086510.018
heart developmentGO:00075073130.018
calcium ion transport into cytosolGO:006040230.018
Fly
neuron neuron synaptic transmissionGO:000727010.018
regulation of cell communicationGO:00106462320.018
single fertilizationGO:000733830.018
regulation of cytokine productionGO:000181730.018
sensory perception of chemical stimulusGO:000760630.018
Fly
single organism organelle organizationGO:19025891990.018
internal protein amino acid acetylationGO:000647520.018
regulation of blood pressureGO:000821710.018
sensory organ developmentGO:00074233930.018
regulation of purine nucleotide catabolic processGO:003312120.018
morphogenesis of an epitheliumGO:00020093330.017
adherens junction organizationGO:003433240.017
inorganic ion transmembrane transportGO:0098660570.017
Mouse Rat Fly
fertilizationGO:000956630.017
extrinsic apoptotic signaling pathwayGO:009719130.017
peptidyl lysine acetylationGO:001839420.017
mitotic dna integrity checkpointGO:004477440.017
response to external stimulusGO:00096052640.017
Fly
regulation of dendrite developmentGO:005077330.017
atp catabolic processGO:000620040.017
positive regulation of catabolic processGO:000989640.017
cellular response to external stimulusGO:007149620.017
regulation of signalingGO:00230512350.017
embryonic organ developmentGO:00485683810.017
chordate embryonic developmentGO:00430092710.017
regulation of signal transductionGO:00099662250.017
cytokinesisGO:000091030.017
regulation of membrane potentialGO:0042391230.016
Fly
actin filament polymerizationGO:003004120.016
negative regulation of cellular processGO:00485232830.016
Fly
rna 3 end processingGO:003112320.016
regulation of autophagyGO:001050630.016
inorganic cation transmembrane transportGO:0098662500.016
Mouse Rat Fly
regulation of protein catabolic processGO:004217610.016
cell cycle g1 s phase transitionGO:004484310.016
single organism localizationGO:19025782250.016
Mouse Rat Fly
cellular localizationGO:0051641970.016
Fly
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.016
Fly
digestive tract developmentGO:00485652650.016
negative regulation of biological processGO:00485193040.016
Fly
positive regulation of i kappab kinase nf kappab signalingGO:004312330.016
regulation of cytoplasmic transportGO:190364940.016
tube morphogenesisGO:00352393490.016
exocytosisGO:000688710.016
multicellular organismal signalingGO:0035637220.016
synaptic vesicle localizationGO:009747910.016
regulation of dendrite morphogenesisGO:004881430.016
cation transmembrane transportGO:0098655650.016
Mouse Rat Fly
protein complex disassemblyGO:004324110.016
single organism transportGO:00447652060.016
Mouse Rat Fly
locomotor rhythmGO:004547530.015
regulation of bindingGO:005109830.015
primary neural tube formationGO:001402010.015
macromolecular complex disassemblyGO:003298410.015
cellular amine metabolic processGO:004410620.015
regulation of gtp catabolic processGO:003312420.015
regulation of macromolecule metabolic processGO:00602553170.015
regulation of transporter activityGO:003240920.015
response to uvGO:000941130.015
g1 s transition of mitotic cell cycleGO:000008210.015
compound eye developmentGO:004874920.015
muscle cell differentiationGO:00426921390.015
triglyceride homeostasisGO:007032820.015
biosynthetic processGO:00090582940.015
nucleic acid transportGO:005065720.015
somatic muscle developmentGO:000752540.015
mitochondrion organizationGO:000700540.015
regulation of protein transportGO:005122330.015
protein localization to nucleusGO:003450430.015
protein acylationGO:004354330.014
regulation of blood vessel sizeGO:005088020.014
regulation of primary metabolic processGO:00800903110.014
regulation of filopodium assemblyGO:005148920.014
regulation of protein complex assemblyGO:004325430.014
regulation of response to stimulusGO:00485832690.014
Fly
regulation of transmembrane transporter activityGO:002289820.014
oxoacid metabolic processGO:0043436310.014
regulation of striated muscle contractionGO:000694220.014
periodic partitioningGO:000736510.014
regulation of cellular metabolic processGO:00313233200.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
cytosolic calcium ion transportGO:006040130.014
Fly
regulation of establishment of protein localizationGO:007020140.014
protein targeting to nucleusGO:004474430.014
negative regulation of catabolic processGO:000989530.014
sequestering of calcium ionGO:005120830.014
Fly
cell part morphogenesisGO:00329902460.014
positive regulation of biological processGO:00485182530.014
cellular response to extracellular stimulusGO:003166820.014
nucleocytoplasmic transportGO:000691340.014
b cell activationGO:004211320.014
protein polymerizationGO:005125840.014
negative regulation of kinase activityGO:003367340.014
regulation of metabolic processGO:00192223590.014
programmed cell deathGO:00125011190.014
small molecule catabolic processGO:004428230.014
cell cycle arrestGO:000705010.014
regulation of cellular amine metabolic processGO:003323800.013
cell matrix adhesionGO:000716040.013
behaviorGO:0007610740.013
Fly
regulation of systemic arterial blood pressureGO:000307310.013
regulation of meiotic cell cycleGO:005144510.013
regulation of sequestering of calcium ionGO:005128240.013
Fly
female sex differentiationGO:004666040.013
organic acid metabolic processGO:0006082310.013
rna metabolic processGO:00160702190.013
actin mediated cell contractionGO:007025210.013
response to carbohydrateGO:000974330.013
regulation of anatomical structure morphogenesisGO:00226031300.013
regulation of protein import into nucleusGO:004230620.013
organonitrogen compound metabolic processGO:1901564740.013
production of molecular mediator of immune responseGO:000244020.013
negative regulation of protein kinase activityGO:000646940.013
cellular response to nutrient levelsGO:003166920.013
regulation of nitrogen compound metabolic processGO:00511712510.013
regulation of neuronal synaptic plasticityGO:004816810.013
central nervous system developmentGO:00074173870.013
Fly
tissue remodelingGO:004877140.013
positive regulation of cell activationGO:005086710.013
regulation of protein polymerizationGO:003227120.013
protein localization to plasma membraneGO:007265910.013
carboxylic acid metabolic processGO:0019752220.013
tube closureGO:006060610.013
neuroblast proliferationGO:000740520.013
glial cell migrationGO:000834730.013
peptide transportGO:001583310.013
smooth muscle contractionGO:000693920.013
phagocytosis engulfmentGO:000691110.013
organic cyclic compound biosynthetic processGO:19013622230.013
neurotransmitter transportGO:000683620.013
establishment of rna localizationGO:005123630.013
positive regulation of cytoskeleton organizationGO:005149530.013
mitotic g2 m transition checkpointGO:004481830.013
developmental programmed cell deathGO:001062340.013
positive regulation of protein polymerizationGO:003227320.013
nucleobase containing compound metabolic processGO:00061392740.013
positive regulation of purine nucleotide catabolic processGO:003312310.012
positive regulation of nucleoside metabolic processGO:004597910.012
aromatic compound biosynthetic processGO:00194382170.012
regulation of cellular amino acid metabolic processGO:000652100.012
transmission of nerve impulseGO:0019226190.012
histone h3 k4 methylationGO:005156820.012
cortical cytoskeleton organizationGO:003086510.012
protein metabolic processGO:00195381830.012
cellular biosynthetic processGO:00442492860.012
regulation of nucleocytoplasmic transportGO:004682220.012
single organism nuclear importGO:190259330.012
regulation of macromolecule biosynthetic processGO:00105562250.012
regulation of cellular ketone metabolic processGO:001056570.012
establishment of synaptic vesicle localizationGO:009748010.012
regulation of metal ion transportGO:001095940.012
positive regulation of myeloid cell differentiationGO:004563920.012
negative regulation of protein serine threonine kinase activityGO:007190120.012
g2 dna damage checkpointGO:003157230.012
cellular amino acid metabolic processGO:000652070.012
negative regulation of reproductive processGO:200024230.012
regulation of mrna processingGO:005068430.012
positive regulation of immune effector processGO:000269930.012
intracellular signal transductionGO:0035556850.012
Mouse Rat Fly
organic cyclic compound metabolic processGO:19013603010.012
cellular macromolecule metabolic processGO:00442603910.012
ventricular cardiac muscle tissue developmentGO:000322930.012
cellular component biogenesisGO:00440851780.012
cellular nitrogen compound biosynthetic processGO:00442712180.012
secondary metabolic processGO:001974830.012
localization of cellGO:00516742440.012
regulation of ion transmembrane transporter activityGO:003241220.012
nuclear importGO:005117030.012
synaptic transmission cholinergicGO:000727140.012
response to glucoseGO:000974930.012
establishment of localization in cellGO:0051649770.012
Fly
positive regulation of cellular component biogenesisGO:004408930.011
regulation of organ growthGO:004662030.011
cation transportGO:0006812810.011
Mouse Rat Fly
gene expressionGO:00104672520.011
cell substrate adherens junction assemblyGO:000704510.011
regulation of dna recombinationGO:000001820.011
ventricular cardiac muscle tissue morphogenesisGO:005501020.011
regulation of carbohydrate metabolic processGO:000610940.011
peptide metabolic processGO:000651810.011
double strand break repairGO:000630230.011
ion transportGO:00068111140.011
Mouse Rat Fly
lysosomal transportGO:000704120.011
cellular carbohydrate metabolic processGO:004426240.011
regulation of epithelial cell proliferationGO:005067830.011
positive regulation of map kinase activityGO:004340630.011
rna transportGO:005065820.011
neuron developmentGO:00486662620.011
regulation of multicellular organismal developmentGO:20000262230.011
protein modification processGO:00362111000.011
negative regulation of cellular catabolic processGO:003133030.011
protein import into nucleusGO:000660630.011
cell deathGO:00082191210.011
locomotionGO:00400113130.011
synaptic vesicle transportGO:004848910.011
cellular ketone metabolic processGO:0042180110.011
growthGO:00400071740.011
regulation of stem cell differentiationGO:200073640.011
adherens junction assemblyGO:003433310.011
deathGO:00162651210.011
leukocyte proliferationGO:007066110.011
specification of symmetryGO:00097992040.011
double strand break repair via homologous recombinationGO:000072410.011
superoxide metabolic processGO:000680120.011
cellular response to starvationGO:000926710.011
nucleobase containing compound transportGO:001593120.011
regulation of rac protein signal transductionGO:003502010.011
mitotic dna damage checkpointGO:004477340.011
cellular response to radiationGO:007147840.011
epidermal cell fate specificationGO:000995740.011
cell morphogenesis involved in differentiationGO:00009041950.011
response to hydrogen peroxideGO:004254230.011
golgi vesicle transportGO:004819330.011
centrosome cycleGO:000709810.011
sequestering of metal ionGO:005123830.011
Fly
macromolecule modificationGO:00434121110.011
muscle cell developmentGO:00550011150.011
angiogenesisGO:00015251580.011
segmentationGO:0035282970.011
intracellular mrna localizationGO:000829810.010
regulation of intracellular protein transportGO:003315730.010
negative regulation of cytoplasmic transportGO:190365020.010
positive regulation of jnk cascadeGO:004633030.010
recombinational repairGO:000072510.010
negative regulation of synapse assemblyGO:005196420.010
positive regulation of cytokine productionGO:000181920.010
positive regulation of cellular amine metabolic processGO:003324000.010
organic substance biosynthetic processGO:19015762890.010
g protein coupled receptor signaling pathwayGO:0007186740.010
Fly
regulation of gtpase activityGO:004308720.010
er to golgi vesicle mediated transportGO:000688810.010
leukocyte mediated cytotoxicityGO:000190910.010
regulation of phGO:000688530.010
regulation of growth rateGO:004000910.010
immune system developmentGO:00025201910.010
entrainment of circadian clockGO:000964920.010
protein stabilizationGO:005082120.010
developmental growthGO:00485891660.010
cell surface receptor signaling pathwayGO:00071663250.010
Fly
negative regulation of protein transportGO:005122430.010
negative regulation of ras protein signal transductionGO:004658010.010
neuron projection morphogenesisGO:00488121610.010
positive regulation of secretionGO:005104710.010
digestive system developmentGO:00551232890.010
nitrogen compound metabolic processGO:00068073190.010
muscle system processGO:0003012200.010
meiotic chromosome segregationGO:004513230.010
neuronal action potentialGO:0019228180.010
regulation of protein modification by small protein conjugation or removalGO:190332030.010
cell killingGO:000190620.010
phosphatidylinositol mediated signalingGO:004801520.010

itpr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
musculoskeletal system diseaseDOID:1700.022
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
muscle tissue diseaseDOID:6600.020
muscular diseaseDOID:008000000.020
cardiovascular system diseaseDOID:128700.019
myopathyDOID:42300.018
heart diseaseDOID:11400.018
cardiomyopathyDOID:005070000.018
intrinsic cardiomyopathyDOID:006003600.018
organ system cancerDOID:005068600.016
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.011
nervous system diseaseDOID:86300.010