Danio rerio

0 known processes

parp12b

poly (ADP-ribose) polymerase family, member 12b

(Aliases: zgc:110593,wu:fc13d08,MGC110593,si:dkeyp-27e10.4)

parp12b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule metabolic processGO:00442603910.185
biosynthetic processGO:00090582940.107
regulation of metabolic processGO:00192223590.103
cellular biosynthetic processGO:00442492860.101
regulation of cellular metabolic processGO:00313233200.097
heterocycle biosynthetic processGO:00181302150.096
macromolecule biosynthetic processGO:00090592270.096
regulation of macromolecule metabolic processGO:00602553170.092
cellular aromatic compound metabolic processGO:00067252950.084
organic substance biosynthetic processGO:19015762890.081
nitrogen compound metabolic processGO:00068073190.081
regulation of primary metabolic processGO:00800903110.080
organic cyclic compound metabolic processGO:19013603010.074
signal transductionGO:00071654550.072
nucleobase containing compound metabolic processGO:00061392740.071
positive regulation of cellular processGO:00485222010.069
positive regulation of biological processGO:00485182530.065
rna metabolic processGO:00160702190.064
nucleocytoplasmic transportGO:000691340.064
nuclear transportGO:005116940.064
heterocycle metabolic processGO:00464832900.063
regulation of nitrogen compound metabolic processGO:00511712510.063
nucleic acid metabolic processGO:00903042440.055
protein metabolic processGO:00195381830.055
cellular nitrogen compound metabolic processGO:00346412900.055
cellular protein metabolic processGO:00442671290.053
single organism metabolic processGO:00447102170.053
regulation of biosynthetic processGO:00098892500.048
aromatic compound biosynthetic processGO:00194382170.046
regulation of protein modification by small protein conjugation or removalGO:190332030.043
regulation of biological qualityGO:00650082630.042
transcription dna templatedGO:00063511810.042
protein modification processGO:00362111000.041
regulation of cellular amino acid metabolic processGO:000652100.039
maintenance of locationGO:005123540.039
regulation of rna biosynthetic processGO:20011412130.039
regulation of developmental processGO:00507932470.039
gene expressionGO:00104672520.039
regulation of rna metabolic processGO:00512522240.038
organic cyclic compound biosynthetic processGO:19013622230.038
cellular amino acid metabolic processGO:000652070.038
cellular macromolecule biosynthetic processGO:00346452240.037
regulation of transcription dna templatedGO:00063552130.037
regulation of cell communicationGO:00106462320.036
hematopoietic or lymphoid organ developmentGO:00485341910.036
atp catabolic processGO:000620040.036
nucleobase containing compound biosynthetic processGO:00346542050.036
establishment of localizationGO:00512342440.036
oxoacid metabolic processGO:0043436310.036
larval developmentGO:000216420.035
regulation of cellular macromolecule biosynthetic processGO:20001122220.035
regulation of protein transportGO:005122330.034
response to chemicalGO:00422213200.034
regulation of signalingGO:00230512350.034
regulation of cellular amine metabolic processGO:003323800.033
regulation of gene expressionGO:00104682650.033
regulation of cellular biosynthetic processGO:00313262450.032
embryonic organ developmentGO:00485683810.032
amine metabolic processGO:000930820.032
negative regulation of protein phosphorylationGO:000193340.032
regulation of epithelial cell proliferationGO:005067830.031
positive regulation of cellular amine metabolic processGO:003324000.031
organic acid metabolic processGO:0006082310.030
cellular protein modification processGO:00064641000.030
positive regulation of transportGO:005105020.030
modification dependent macromolecule catabolic processGO:004363230.030
proteasomal protein catabolic processGO:001049820.030
regulation of cell shapeGO:000836010.030
macromolecule modificationGO:00434121110.030
ubiquitin dependent protein catabolic processGO:000651130.029
carboxylic acid metabolic processGO:0019752220.029
regulation of signal transductionGO:00099662250.029
cellular ketone metabolic processGO:0042180110.028
response to organic substanceGO:00100331530.028
positive regulation of cellular component biogenesisGO:004408930.028
cellular component movementGO:00069283350.028
phagocytosisGO:000690930.028
homeostasis of number of cellsGO:0048872620.028
intracellular signal transductionGO:0035556850.027
regulation of protein ubiquitinationGO:003139630.027
neuron developmentGO:00486662620.027
immune system developmentGO:00025201910.027
rna biosynthetic processGO:00327741810.027
neuron differentiationGO:00301823530.027
regulation of nucleobase containing compound metabolic processGO:00192192500.026
regulation of synapse organizationGO:005080730.026
generation of neuronsGO:00486993850.026
positive regulation of cellular amino acid metabolic processGO:004576400.026
transportGO:00068102200.026
nucleic acid templated transcriptionGO:00976591810.026
autophagyGO:000691440.026
regulation of macromolecule biosynthetic processGO:00105562250.026
chromosome organizationGO:0051276310.025
negative regulation of biological processGO:00485193040.025
erythrocyte homeostasisGO:0034101550.025
regulation of response to stimulusGO:00485832690.025
cellular amine metabolic processGO:004410620.025
regulation of synapse assemblyGO:005196330.025
nucleoside monophosphate catabolic processGO:000912540.025
positive regulation of catabolic processGO:000989640.025
protein localization to nucleusGO:003450430.025
mononuclear cell proliferationGO:003294310.024
hemopoiesisGO:00300971830.024
brain developmentGO:00074202930.024
transcription from rna polymerase ii promoterGO:0006366800.024
centrosome organizationGO:005129710.024
protein acetylationGO:000647320.024
cell projection organizationGO:00300302840.023
regulation of establishment of protein localizationGO:007020140.023
negative regulation of protein kinase activityGO:000646940.023
small molecule metabolic processGO:0044281770.023
immune system processGO:00023762410.023
organelle organizationGO:00069962270.023
leukocyte proliferationGO:007066110.023
erk1 and erk2 cascadeGO:007037140.023
lipid storageGO:001991510.023
ribonucleoside monophosphate catabolic processGO:000915840.022
nuclear exportGO:005116810.022
multicellular organism growthGO:003526440.022
cell surface receptor signaling pathwayGO:00071663250.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
regulation of cellular ketone metabolic processGO:001056570.022
regulation of multicellular organismal developmentGO:20000262230.022
response to nutrientGO:000758430.022
single organism nuclear importGO:190259330.022
regulation of protein localization to nucleusGO:190018020.022
embryo development ending in birth or egg hatchingGO:00097922710.022
phosphorus metabolic processGO:00067931090.021
nuclear importGO:005117030.021
establishment of protein localization to organelleGO:007259440.021
positive regulation of epithelial cell proliferationGO:005067910.021
cellular nitrogen compound biosynthetic processGO:00442712180.021
synaptic growth at neuromuscular junctionGO:005112420.021
regulation of bindingGO:005109830.021
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.021
organonitrogen compound metabolic processGO:1901564740.020
protein targeting to nucleusGO:004474430.020
membrane lipid biosynthetic processGO:004646720.020
cellular response to extracellular stimulusGO:003166820.020
regulation of multicellular organism growthGO:004001440.020
positive regulation of metabolic processGO:00098931080.020
lymphocyte proliferationGO:004665110.020
negative regulation of cellular processGO:00485232830.020
macromolecule methylationGO:0043414190.020
chordate embryonic developmentGO:00430092710.019
head developmentGO:00603223030.019
positive regulation of chromatin modificationGO:190331010.019
proteolysis involved in cellular protein catabolic processGO:005160330.019
central nervous system developmentGO:00074173870.019
response to carbohydrateGO:000974330.019
regulation of synaptic growth at neuromuscular junctionGO:000858210.019
cell morphogenesisGO:00009022890.019
regulation of cytokine productionGO:000181730.019
regulation of stem cell proliferationGO:007209120.019
protein importGO:001703830.019
negative regulation of kinase activityGO:003367340.019
regulation of cytoplasmic transportGO:190364940.019
positive regulation of nitrogen compound metabolic processGO:0051173690.018
stem cell proliferationGO:007208940.018
protein heterooligomerizationGO:005129110.018
regulation of hormone secretionGO:004688320.018
cell morphogenesis involved in differentiationGO:00009041950.018
fertilizationGO:000956630.018
cellular component assemblyGO:00226071700.018
agingGO:000756820.018
regulation of cell differentiationGO:00455951420.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
tube morphogenesisGO:00352393490.017
phosphorylationGO:0016310690.017
homeostatic processGO:00425921420.017
cell substrate adhesionGO:003158940.017
protein acylationGO:004354330.017
regulation of purine nucleotide catabolic processGO:003312120.017
regulation of nucleocytoplasmic transportGO:004682220.017
small molecule catabolic processGO:004428230.017
regulation of mrna processingGO:005068430.017
regulation of cell activationGO:005086510.017
positive regulation of canonical wnt signaling pathwayGO:009026340.017
cellular response to external stimulusGO:007149620.017
regulation of catalytic activityGO:0050790550.016
adherens junction organizationGO:003433240.016
regulation of erk1 and erk2 cascadeGO:007037240.016
response to hexoseGO:000974630.016
heart developmentGO:00075073130.016
single fertilizationGO:000733830.016
peptidyl lysine acetylationGO:001839420.016
female sex differentiationGO:004666040.016
regulation of autophagyGO:001050630.016
regulation of jak stat cascadeGO:004642530.016
internal protein amino acid acetylationGO:000647520.016
purine ribonucleoside monophosphate catabolic processGO:000916940.016
cell part morphogenesisGO:00329902460.016
positive regulation of cytoskeleton organizationGO:005149530.016
carbohydrate derivative metabolic processGO:1901135610.016
covalent chromatin modificationGO:0016569200.016
regulation of protein complex assemblyGO:004325430.016
negative regulation of catabolic processGO:000989530.016
regulation of metal ion transportGO:001095940.016
meiotic nuclear divisionGO:000712640.015
response to uvGO:000941130.015
amino acid transportGO:000686520.015
protein import into nucleusGO:000660630.015
extrinsic apoptotic signaling pathwayGO:009719130.015
centrosome duplicationGO:005129810.015
response to stressGO:00069502630.015
positive regulation of chromosome organizationGO:200125210.015
positive regulation of muscle cell differentiationGO:005114910.015
primary neural tube formationGO:001402010.015
internal peptidyl lysine acetylationGO:001839320.015
positive regulation of protein complex assemblyGO:003133420.015
regulation of multicellular organismal processGO:00512392770.015
negative regulation of dna metabolic processGO:005105340.015
positive regulation of macromolecule metabolic processGO:0010604930.015
negative regulation of nuclear divisionGO:005178430.015
cell projection morphogenesisGO:00488582440.015
cell migration involved in gastrulationGO:0042074790.015
response to monosaccharideGO:003428430.015
b cell activationGO:004211320.015
regulation of inflammatory responseGO:005072720.015
regulation of cellular component organizationGO:0051128860.015
digestive tract morphogenesisGO:00485462310.015
regulation of transcription from rna polymerase ii promoterGO:00063571140.015
negative regulation of protein serine threonine kinase activityGO:007190120.014
regulation of molecular functionGO:0065009700.014
negative regulation of mapk cascadeGO:004340940.014
gastrulationGO:00073692080.014
tube closureGO:006060610.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
protein polymerizationGO:005125840.014
cellular component morphogenesisGO:00329893360.014
positive regulation of cell cycleGO:004578730.014
response to vitaminGO:003327330.014
digestive system developmentGO:00551232890.014
regulation of dna replicationGO:000627530.014
cellular response to radiationGO:007147840.014
negative regulation of immune responseGO:005077720.014
neuron projection morphogenesisGO:00488121610.014
regulation of protein targetingGO:190353320.014
lipid catabolic processGO:001604240.014
hormone transportGO:000991420.014
cellular amide metabolic processGO:004360340.014
localization of cellGO:00516742440.014
regulation of reactive oxygen species metabolic processGO:200037720.014
carbohydrate derivative biosynthetic processGO:1901137430.014
negative regulation of response to cytokine stimulusGO:006076120.014
neuroblast proliferationGO:000740520.013
positive regulation of cell communicationGO:0010647560.013
purine nucleoside monophosphate catabolic processGO:000912840.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
negative regulation of nucleocytoplasmic transportGO:004682320.013
regulation of response to cytokine stimulusGO:006075930.013
negative regulation of defense responseGO:003134820.013
microtubule organizing center organizationGO:003102310.013
peptidyl threonine modificationGO:001821010.013
regulation of reproductive processGO:200024140.013
regulation of protein catabolic processGO:004217610.013
regulation of cellular protein metabolic processGO:0032268520.013
carbohydrate homeostasisGO:003350010.013
long chain fatty acid metabolic processGO:000167610.013
skeletal system developmentGO:00015011810.013
meiosis iGO:000712710.013
cell migrationGO:00164772370.013
positive regulation of histone modificationGO:003105810.013
muscle structure developmentGO:00610611960.013
centrosome cycleGO:000709810.013
regulation of neural precursor cell proliferationGO:200017730.013
positive regulation of cellular catabolic processGO:003133130.013
modification dependent protein catabolic processGO:001994130.013
positive regulation of map kinase activityGO:004340630.013
cellular modified amino acid metabolic processGO:000657530.013
peptide transportGO:001583310.013
alpha amino acid metabolic processGO:190160530.013
secondary metabolic processGO:001974830.013
meiotic cell cycle processGO:190304630.013
stem cell divisionGO:001714510.013
ameboidal type cell migrationGO:00016671430.012
cellular carbohydrate metabolic processGO:004426240.012
vacuolar transportGO:000703420.012
cell motilityGO:00488702440.012
single organism organelle organizationGO:19025891990.012
negative regulation of protein localization to nucleusGO:190018120.012
rna modificationGO:000945120.012
locomotionGO:00400113130.012
protein phosphorylationGO:0006468470.012
cellular protein catabolic processGO:004425740.012
membrane invaginationGO:001032410.012
histone h3 k4 methylationGO:005156820.012
embryonic organ morphogenesisGO:00485622740.012
axonogenesisGO:00074091520.012
erythrocyte differentiationGO:0030218540.012
tyrosine phosphorylation of stat proteinGO:000726010.012
peptidyl serine modificationGO:001820920.012
protein stabilizationGO:005082120.012
regulation of calcium ion transportGO:005192420.012
peptidyl threonine phosphorylationGO:001810710.012
cellular response to chemical stimulusGO:00708871570.012
neuron projection developmentGO:00311751800.012
protein modification by small protein removalGO:007064610.012
positive regulation of cell activationGO:005086710.012
histone deacetylationGO:001657520.012
female gonad developmentGO:000858540.012
organic acid catabolic processGO:001605430.012
female meiotic divisionGO:000714320.012
regulation of intracellular protein transportGO:003315730.012
blood vessel developmentGO:00015682460.012
establishment of localization in cellGO:0051649770.012
double strand break repair via homologous recombinationGO:000072410.012
cell agingGO:000756920.012
negative regulation of response to stimulusGO:00485851040.012
cytoskeleton dependent cytokinesisGO:006164030.012
cytokinesisGO:000091030.012
positive regulation of secretionGO:005104710.012
apoptotic process involved in developmentGO:190274220.012
inositol lipid mediated signalingGO:004801720.012
mitotic dna integrity checkpointGO:004477440.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of phosphorus metabolic processGO:0051174430.011
primitive hemopoiesisGO:0060215270.011
positive regulation of nucleoside metabolic processGO:004597910.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
positive regulation of secretion by cellGO:190353210.011
response to drugGO:004249330.011
negative regulation of protein import into nucleusGO:004230820.011
multi organism processGO:00517041340.011
double strand break repairGO:000630230.011
hormone secretionGO:004687920.011
regulation of tyrosine phosphorylation of stat proteinGO:004250910.011
cell matrix adhesionGO:000716040.011
response to glucoseGO:000974930.011
negative regulation of chromosome organizationGO:200125110.011
positive regulation of nucleotide catabolic processGO:003081310.011
cell substrate junction assemblyGO:000704420.011
regulation of i kappab kinase nf kappab signalingGO:004312240.011
sensory organ morphogenesisGO:00905962000.011
negative regulation of intracellular transportGO:003238730.011
rna localizationGO:000640340.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
endosomal transportGO:001619720.011
alternative mrna splicing via spliceosomeGO:000038010.011
ion transportGO:00068111140.011
positive regulation of protein polymerizationGO:003227320.011
renal system developmentGO:0072001940.011
specification of axis polarityGO:006500140.011
sensory organ developmentGO:00074233930.011
development of primary female sexual characteristicsGO:004654540.011
growthGO:00400071740.011
regulation of protein metabolic processGO:0051246560.011
negative chemotaxisGO:005091910.011
mitotic dna damage checkpointGO:004477340.011
single organism transportGO:00447652060.011
locomotor rhythmGO:004547530.011
regulation of protein bindingGO:004339330.011
skeletal system morphogenesisGO:00487051020.011
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.011
regulation of circadian rhythmGO:004275240.011
response to corticosteroidGO:003196010.011
regulation of histone methylationGO:003106030.011
negative regulation of macromolecule metabolic processGO:0010605760.011
microtubule cytoskeleton organization involved in mitosisGO:190285010.011
cellular response to hypoxiaGO:007145610.011
regulation of intracellular signal transductionGO:1902531570.011
actin filament polymerizationGO:003004120.011
positive regulation of jak stat cascadeGO:004642720.011
dna templated transcription initiationGO:000635210.010
digestive tract developmentGO:00485652650.010
vasculature developmentGO:00019442780.010
negative regulation of signalingGO:0023057960.010
spindle assembly involved in mitosisGO:009030710.010
negative regulation of cytoplasmic transportGO:190365020.010
rna transportGO:005065820.010
nucleic acid transportGO:005065720.010
sensory perception of painGO:001923310.010
positive regulation of striated muscle cell differentiationGO:005115510.010
morphogenesis of an epitheliumGO:00020093330.010
axon developmentGO:00615641660.010
developmental programmed cell deathGO:001062340.010
cognitionGO:005089010.010
cell morphogenesis involved in neuron differentiationGO:00486671630.010
response to glucocorticoidGO:005138410.010
cellular response to decreased oxygen levelsGO:003629410.010
regulation of nucleoside metabolic processGO:000911820.010
somatic muscle developmentGO:000752540.010
toll like receptor signaling pathwayGO:000222440.010
negative regulation of metabolic processGO:0009892860.010
regulation of protein import into nucleusGO:004230620.010
embryonic hemopoiesisGO:0035162530.010
i kappab kinase nf kappab signalingGO:000724940.010
negative regulation of cellular catabolic processGO:003133030.010
production of molecular mediator of immune responseGO:000244020.010
negative regulation of cellular metabolic processGO:0031324770.010
single organism localizationGO:19025782250.010
mitochondrial transportGO:000683920.010
regulation of epithelial to mesenchymal transitionGO:001071730.010

parp12b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
musculoskeletal system diseaseDOID:1700.015
disease of metabolismDOID:001466700.015
inherited metabolic disorderDOID:65500.014
nervous system diseaseDOID:86300.013
immune system diseaseDOID:291400.012
sensory system diseaseDOID:005015500.010