Danio rerio

93 known processes

rtn4a

reticulon 4a

(Aliases: rtn4,zgc:92163,wu:fb22f12,nogo,wu:fd61a07,wu:fb17a02)

rtn4a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
locomotionGO:00400113130.193
cellular component assemblyGO:00226071700.181
embryonic viscerocranium morphogenesisGO:0048703520.158
skeletal system developmentGO:00015011810.152
central nervous system developmentGO:00074173870.146
embryonic skeletal system morphogenesisGO:0048704930.144
generation of neuronsGO:00486993850.142
cellular component movementGO:00069283350.131
embryonic skeletal system developmentGO:0048706970.125
embryonic cranial skeleton morphogenesisGO:0048701900.114
response to chemicalGO:00422213200.109
dicarboxylic acid metabolic processGO:004364810.108
extrinsic apoptotic signaling pathwayGO:009719130.107
ubiquitin dependent protein catabolic processGO:000651130.103
astrocyte differentiationGO:004870810.097
camera type eye developmentGO:00430102220.094
lateral line developmentGO:0048882660.093
lipid catabolic processGO:001604240.083
skeletal system morphogenesisGO:00487051020.080
brain developmentGO:00074202930.079
chordate embryonic developmentGO:00430092710.075
embryo development ending in birth or egg hatchingGO:00097922710.074
organonitrogen compound metabolic processGO:1901564740.073
embryonic organ morphogenesisGO:00485622740.072
taxisGO:00423301090.072
neural crest cell differentiationGO:0014033720.072
cranial nerve developmentGO:0021545420.071
neuromast developmentGO:0048884460.066
oxoacid metabolic processGO:0043436310.066
neural crest cell developmentGO:0014032620.064
single organism metabolic processGO:00447102170.063
oxidation reduction processGO:0055114410.059
cell surface receptor signaling pathwayGO:00071663250.058
sensory system developmentGO:0048880760.058
modification dependent macromolecule catabolic processGO:004363230.055
lateral line system developmentGO:0048925760.054
sodium ion transmembrane transportGO:0035725210.054
neuron differentiationGO:00301823530.052
transmission of nerve impulseGO:0019226190.052
cellular amino acid biosynthetic processGO:000865220.050
larval developmentGO:000216420.050
nerve developmentGO:0021675450.049
positive regulation of cellular amino acid metabolic processGO:004576400.049
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.048
regulation of cellular amine metabolic processGO:003323800.046
cellular lipid metabolic processGO:0044255360.044
homophilic cell adhesion via plasma membrane adhesion moleculesGO:000715640.044
proteasomal protein catabolic processGO:001049820.044
optic nerve developmentGO:0021554150.043
organic acid metabolic processGO:0006082310.042
regulation of biological qualityGO:00650082630.042
Human Mouse
homeostasis of number of cellsGO:0048872620.042
mitochondrion organizationGO:000700540.040
mesenchymal cell developmentGO:0014031780.040
Mouse
regulation of dna templated transcription in response to stressGO:004362000.039
embryonic heart tube developmentGO:00350501330.039
cell morphogenesis involved in neuron differentiationGO:00486671630.039
modification dependent protein catabolic processGO:001994130.038
membrane lipid biosynthetic processGO:004646720.038
small molecule metabolic processGO:0044281770.037
cell part morphogenesisGO:00329902460.037
cell migrationGO:00164772370.037
agingGO:000756820.036
alpha amino acid metabolic processGO:190160530.035
embryonic organ developmentGO:00485683810.035
axon guidanceGO:0007411860.034
cell substrate adhesionGO:003158940.033
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361800.033
androgen metabolic processGO:000820920.033
cellular respirationGO:004533330.032
establishment or maintenance of epithelial cell apical basal polarityGO:0045197110.031
cellular response to hypoxiaGO:007145610.031
response to stressGO:00069502630.031
neuron developmentGO:00486662620.031
proteolysis involved in cellular protein catabolic processGO:005160330.030
cell deathGO:00082191210.030
cellular component biogenesisGO:00440851780.030
regulation of peptidyl tyrosine phosphorylationGO:005073010.030
immune system developmentGO:00025201910.030
peptidyl serine phosphorylationGO:001810510.030
regulation of reproductive processGO:200024140.029
monovalent inorganic cation transportGO:0015672420.029
organelle organizationGO:00069962270.029
Human
lipid metabolic processGO:0006629520.029
positive regulation of cell adhesionGO:004578510.028
purine ribonucleoside monophosphate catabolic processGO:000916940.028
lipid storageGO:001991510.028
phosphatidylinositol 3 kinase signalingGO:001406520.028
neuronal action potentialGO:0019228180.028
positive regulation of small gtpase mediated signal transductionGO:005105710.028
growthGO:00400071740.028
Human Mouse
negative regulation of protein kinase activityGO:000646940.027
striated muscle cell differentiationGO:00511461290.027
carboxylic acid metabolic processGO:0019752220.027
head developmentGO:00603223030.026
cell morphogenesisGO:00009022890.026
alcohol biosynthetic processGO:004616520.026
eye developmentGO:00016542770.025
leukocyte proliferationGO:007066110.025
erythrocyte differentiationGO:0030218540.025
adult behaviorGO:003053420.025
long chain fatty acid metabolic processGO:000167610.025
sphingolipid biosynthetic processGO:003014820.025
cellular protein catabolic processGO:004425740.025
negative regulation of protein phosphorylationGO:000193340.025
regulation of multicellular organism growthGO:004001440.025
multicellular organism growthGO:003526440.024
single organism transportGO:00447652060.024
cellular response to decreased oxygen levelsGO:003629410.024
atp catabolic processGO:000620040.024
system processGO:00030081850.023
glucose importGO:004632320.023
vasculature developmentGO:00019442780.023
sensory organ morphogenesisGO:00905962000.022
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
protein complex biogenesisGO:0070271300.022
cellular amine metabolic processGO:004410620.022
ribonucleoside monophosphate catabolic processGO:000915840.022
response to decreased oxygen levelsGO:0036293250.022
motor neuron axon guidanceGO:0008045230.022
muscle cell developmentGO:00550011150.022
neuron projection developmentGO:00311751800.022
tube morphogenesisGO:00352393490.021
amine metabolic processGO:000930820.021
blood vessel morphogenesisGO:00485142160.021
peptidyl serine modificationGO:001820920.021
cellular component maintenanceGO:004395430.021
positive regulation of transportGO:005105020.020
nitrogen compound metabolic processGO:00068073190.020
response to drugGO:004249330.020
cellular component morphogenesisGO:00329893360.020
muscle tissue developmentGO:00605371100.019
response to organic substanceGO:00100331530.019
peripheral nervous system developmentGO:0007422550.019
organic cyclic compound metabolic processGO:19013603010.019
cellular modified amino acid metabolic processGO:000657530.019
axon ensheathment in central nervous systemGO:003229120.019
autonomic nervous system developmentGO:0048483190.019
forebrain cell migrationGO:002188510.019
Mouse
maintenance of locationGO:005123540.018
regulation of synapse assemblyGO:005196330.018
adherens junction maintenanceGO:003433420.018
establishment or maintenance of apical basal cell polarityGO:0035088120.018
mechanosensory behaviorGO:000763820.018
cell motilityGO:00488702440.018
forebrain developmentGO:0030900960.018
Mouse
establishment of localizationGO:00512342440.018
regulation of cellular phGO:003064110.018
response to hypoxiaGO:0001666250.017
negative regulation of kinase activityGO:003367340.017
urogenital system developmentGO:0001655970.017
cellular amino acid metabolic processGO:000652070.017
action potentialGO:0001508190.017
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.017
homeostatic processGO:00425921420.017
carboxylic acid catabolic processGO:004639530.017
energy reserve metabolic processGO:000611220.017
fatty acid beta oxidationGO:000663510.017
regulation of transmembrane transportGO:0034762180.017
hormone metabolic processGO:0042445190.016
myeloid cell homeostasisGO:0002262560.016
meiotic cell cycle processGO:190304630.016
neuron projection guidanceGO:0097485860.016
synaptic growth at neuromuscular junctionGO:005112420.016
establishment of protein localization to organelleGO:007259440.016
neural crest cell migrationGO:0001755420.016
blood vessel developmentGO:00015682460.016
positive regulation of stem cell proliferationGO:200064810.016
circadian sleep wake cycle sleepGO:005080210.016
neuron neuron synaptic transmissionGO:000727010.016
positive regulation of apoptotic signaling pathwayGO:200123510.016
heterocycle metabolic processGO:00464832900.016
transmembrane transportGO:00550851200.016
renal system developmentGO:0072001940.016
multicellular organismal signalingGO:0035637220.015
synaptic transmission cholinergicGO:000727140.015
positive regulation of cellular catabolic processGO:003133130.015
cellular aldehyde metabolic processGO:000608140.015
regulation of cellular metabolic processGO:00313233200.015
cell agingGO:000756920.015
gtp catabolic processGO:000618420.015
epithelial tube morphogenesisGO:00605621480.015
purine nucleoside monophosphate catabolic processGO:000912840.015
cellular ketone metabolic processGO:0042180110.015
regulation of cellular component organizationGO:0051128860.015
Human Mouse
regulation of cellular amino acid metabolic processGO:000652100.014
protein complex assemblyGO:0006461300.014
neuron projection morphogenesisGO:00488121610.014
transportGO:00068102200.014
negative regulation of synapse assemblyGO:005196420.014
positive regulation of cellular amine metabolic processGO:003324000.014
programmed cell deathGO:00125011190.014
long chain fatty acid biosynthetic processGO:004275910.014
regulation of cellular ketone metabolic processGO:001056570.014
cellular response to oxygen levelsGO:007145310.014
fatty acid biosynthetic processGO:000663340.014
axon developmentGO:00615641660.014
muscle structure developmentGO:00610611960.014
hydrogen peroxide metabolic processGO:004274320.014
stem cell developmentGO:0048864820.014
Mouse
positive regulation of catabolic processGO:000989640.014
response to external stimulusGO:00096052640.014
positive regulation of glucose importGO:004632610.013
regulation of cell activationGO:005086510.013
generation of precursor metabolites and energyGO:000609150.013
hemopoiesisGO:00300971830.013
biosynthetic processGO:00090582940.013
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.013
heterophilic cell cell adhesion via plasma membrane cell adhesion moleculesGO:000715720.013
positive regulation of gliogenesisGO:001401520.013
single organism localizationGO:19025782250.013
cellular response to external stimulusGO:007149620.013
negative regulation of signal transductionGO:0009968940.013
positive regulation of map kinase activityGO:004340630.013
muscle organ developmentGO:00075171010.013
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.013
nucleoside monophosphate catabolic processGO:000912540.013
negative regulation of protein kinase b signalingGO:005189820.013
mesenchymal cell differentiationGO:0048762870.013
Mouse
lymphocyte proliferationGO:004665110.013
negative regulation of signalingGO:0023057960.013
golgi vesicle transportGO:004819330.013
macromolecular complex assemblyGO:0065003350.013
circadian sleep wake cycleGO:004274520.012
regulation of cell communicationGO:00106462320.012
regulation of membrane potentialGO:0042391230.012
determination of bilateral symmetryGO:00098552040.012
regulation of glucose transportGO:001082710.012
cellular response to organic substanceGO:00713101050.012
regulation of sodium ion transmembrane transporter activityGO:200064910.012
multicellular organismal response to stressGO:003355520.012
positive regulation of glucose transportGO:001082810.012
pigmentationGO:0043473850.012
organic substance biosynthetic processGO:19015762890.012
embryonic heart tube morphogenesisGO:00031431080.012
positive regulation of signal transductionGO:0009967560.012
lipid homeostasisGO:005508830.012
erythrocyte homeostasisGO:0034101550.012
cellular macromolecule metabolic processGO:00442603910.012
regulation of autophagyGO:001050630.012
phagocytosisGO:000690930.011
response to abiotic stimulusGO:00096281220.011
positive regulation of striated muscle cell differentiationGO:005115510.011
negative regulation of response to stimulusGO:00485851040.011
kidney developmentGO:0001822920.011
mononuclear cell proliferationGO:003294310.011
cellular lipid catabolic processGO:004424230.011
cell projection organizationGO:00300302840.011
regulation of phGO:000688530.011
monocarboxylic acid biosynthetic processGO:0072330120.011
primary neural tube formationGO:001402010.011
negative regulation of cellular processGO:00485232830.011
meiotic chromosome segregationGO:004513230.011
cognitionGO:005089010.011
striated muscle tissue developmentGO:00147061100.011
cellular response to chemical stimulusGO:00708871570.011
fin developmentGO:0033333770.011
organic cyclic compound biosynthetic processGO:19013622230.011
negative regulation of biological processGO:00485193040.011
carboxylic acid biosynthetic processGO:0046394120.011
chemosensory behaviorGO:000763510.010
small molecule catabolic processGO:004428230.010
sodium ion transportGO:0006814240.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
cell projection morphogenesisGO:00488582440.010
cellular monovalent inorganic cation homeostasisGO:003000420.010
skeletal muscle organ developmentGO:0060538780.010
myeloid cell differentiationGO:0030099860.010
cellular response to nutrient levelsGO:003166920.010
cell junction maintenanceGO:003433120.010
regulation of protein localization to nucleusGO:190018020.010
muscle fiber developmentGO:0048747520.010
negative regulation of dna metabolic processGO:005105340.010

rtn4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.087
nervous system diseaseDOID:86300.078
cardiovascular system diseaseDOID:128700.025
disease of metabolismDOID:001466700.017
central nervous system diseaseDOID:33100.017
neurodegenerative diseaseDOID:128900.017
heart diseaseDOID:11400.012
connective tissue diseaseDOID:6500.011
musculoskeletal system diseaseDOID:1700.011