Danio rerio

18 known processes

jam2a

junctional adhesion molecule 2a

(Aliases: sb:cb1002,jam2)

jam2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
brain developmentGO:00074202930.543
cell motilityGO:00488702440.539
head developmentGO:00603223030.486
syncytium formationGO:0006949120.451
myoblast fusionGO:0007520100.436
cellular component movementGO:00069283350.416
central nervous system developmentGO:00074173870.415
neuron developmentGO:00486662620.413
nucleobase containing compound metabolic processGO:00061392740.400
muscle structure developmentGO:00610611960.396
regulation of developmental processGO:00507932470.386
neuron differentiationGO:00301823530.375
sarcomere organizationGO:0045214260.361
localization of cellGO:00516742440.345
regulation of rna biosynthetic processGO:20011412130.342
nitrogen compound metabolic processGO:00068073190.333
organic cyclic compound metabolic processGO:19013603010.320
generation of neuronsGO:00486993850.308
nucleic acid metabolic processGO:00903042440.305
gene expressionGO:00104672520.297
muscle organ developmentGO:00075171010.296
heterocycle biosynthetic processGO:00181302150.292
cell projection organizationGO:00300302840.290
locomotionGO:00400113130.290
anterior posterior pattern specificationGO:00099521520.285
myotube differentiationGO:0014902450.260
cellular macromolecule metabolic processGO:00442603910.259
cell migrationGO:00164772370.259
convergent extensionGO:00600261180.237
somitogenesisGO:0001756870.230
regulation of muscle contractionGO:000693730.230
regulation of transcription dna templatedGO:00063552130.221
morphogenesis of an epitheliumGO:00020093330.217
nucleic acid templated transcriptionGO:00976591810.209
cellular component morphogenesisGO:00329893360.205
regulation of cell developmentGO:00602841000.202
taxisGO:00423301090.200
regulation of biological qualityGO:00650082630.196
regulation of cellular macromolecule biosynthetic processGO:20001122220.187
organic substance biosynthetic processGO:19015762890.185
skeletal muscle organ developmentGO:0060538780.170
camera type eye developmentGO:00430102220.165
positive regulation of biological processGO:00485182530.164
syncytium formation by plasma membrane fusionGO:0000768120.161
leukocyte homeostasisGO:000177620.159
somite developmentGO:0061053960.158
response to chemicalGO:00422213200.158
cellular macromolecule biosynthetic processGO:00346452240.156
system processGO:00030081850.151
heterocycle metabolic processGO:00464832900.148
embryo development ending in birth or egg hatchingGO:00097922710.148
tube morphogenesisGO:00352393490.145
single organism organelle organizationGO:19025891990.140
regulation of metabolic processGO:00192223590.140
regulation of nucleobase containing compound metabolic processGO:00192192500.137
cellular biosynthetic processGO:00442492860.135
cell part morphogenesisGO:00329902460.131
chemotaxisGO:00069351040.130
immune system processGO:00023762410.129
regulation of anatomical structure morphogenesisGO:00226031300.128
hematopoietic or lymphoid organ developmentGO:00485341910.127
muscle cell differentiationGO:00426921390.124
rna biosynthetic processGO:00327741810.122
regulation of primary metabolic processGO:00800903110.121
circulatory system processGO:0003013870.121
neutrophil migrationGO:1990266100.116
cellular nitrogen compound metabolic processGO:00346412900.113
positive regulation of nitrogen compound metabolic processGO:0051173690.106
regulation of macromolecule metabolic processGO:00602553170.106
regulation of nitrogen compound metabolic processGO:00511712510.105
aromatic compound biosynthetic processGO:00194382170.104
regulation of gene expressionGO:00104682650.102
regulation of reactive oxygen species metabolic processGO:200037720.101
rna metabolic processGO:00160702190.100
single organismal cell cell adhesionGO:0016337290.098
skeletal muscle tissue developmentGO:0007519670.096
neuron projection developmentGO:00311751800.094
blood vessel developmentGO:00015682460.093
regionalizationGO:00030022740.089
cell morphogenesis involved in neuron differentiationGO:00486671630.088
epithelial tube morphogenesisGO:00605621480.086
organelle assemblyGO:00709251100.086
striated muscle cell differentiationGO:00511461290.086
positive regulation of cellular biosynthetic processGO:0031328680.086
lateral line system developmentGO:0048925760.085
Zebrafish
cellular nitrogen compound biosynthetic processGO:00442712180.084
regulation of cellular metabolic processGO:00313233200.083
nitric oxide metabolic processGO:004620920.081
cellular aromatic compound metabolic processGO:00067252950.079
convergent extension involved in gastrulationGO:0060027710.078
cartilage condensationGO:000150230.078
cell substrate adhesionGO:003158940.076
regulation of biosynthetic processGO:00098892500.075
regulation of response to stimulusGO:00485832690.075
mesenchyme developmentGO:00604851270.075
neuron migrationGO:0001764220.073
reactive nitrogen species metabolic processGO:200105700.073
response to external stimulusGO:00096052640.072
regulation of cellular biosynthetic processGO:00313262450.071
ameboidal type cell migrationGO:00016671430.070
cell morphogenesisGO:00009022890.070
gamete generationGO:0007276330.069
organelle organizationGO:00069962270.069
granulocyte chemotaxisGO:0071621110.068
regulation of behaviorGO:0050795240.068
adherens junction maintenanceGO:003433420.067
regulation of cell shapeGO:000836010.066
regulation of macromolecule biosynthetic processGO:00105562250.066
regulation of cell differentiationGO:00455951420.064
digestive system developmentGO:00551232890.063
response to glucoseGO:000974930.062
regulation of organelle assemblyGO:190211540.061
tube formationGO:0035148250.061
amine metabolic processGO:000930820.060
regulation of neutrophil chemotaxisGO:009002250.060
stem cell differentiationGO:00488631170.059
regulation of myotube differentiationGO:001083020.059
larval developmentGO:000216420.058
transmission of nerve impulseGO:0019226190.057
neutrophil chemotaxisGO:0030593100.056
cellular amine metabolic processGO:004410620.056
muscle cell developmentGO:00550011150.056
cellular component assembly involved in morphogenesisGO:00109271070.055
cytoskeleton organizationGO:0007010960.055
negative regulation of macromolecule biosynthetic processGO:0010558480.055
cell morphogenesis involved in differentiationGO:00009041950.054
homeostatic processGO:00425921420.054
purine nucleoside monophosphate catabolic processGO:000912840.054
negative regulation of cellular processGO:00485232830.054
Mouse
response to vitaminGO:003327330.053
negative regulation of nucleobase containing compound metabolic processGO:0045934590.053
striated muscle cell developmentGO:00550021080.053
regulation of skeletal muscle fiber developmentGO:004874220.052
embryonic organ developmentGO:00485683810.052
cell chemotaxisGO:0060326170.052
regulation of locomotionGO:0040012550.051
cell matrix adhesionGO:000716040.051
transcription dna templatedGO:00063511810.050
cellular component assemblyGO:00226071700.050
regenerationGO:0031099910.050
branching morphogenesis of a nerveGO:004875540.048
regulation of cellular component organizationGO:0051128860.048
striated muscle tissue developmentGO:00147061100.048
sensory organ developmentGO:00074233930.047
biological adhesionGO:0022610400.047
Mouse
regulation of immune system processGO:0002682340.047
regulation of neutrophil migrationGO:190262260.047
regulation of cellular amine metabolic processGO:003323800.047
blood vessel morphogenesisGO:00485142160.047
organic cyclic compound biosynthetic processGO:19013622230.046
regulation of nucleic acid templated transcriptionGO:19035062130.046
immune system developmentGO:00025201910.046
ventricular cardiac myofibril assemblyGO:005500540.046
leukocyte chemotaxisGO:0030595120.045
response to axon injuryGO:0048678140.045
hematopoietic progenitor cell differentiationGO:0002244230.045
behaviorGO:0007610740.044
chordate embryonic developmentGO:00430092710.044
nitric oxide biosynthetic processGO:000680920.044
spermatid differentiationGO:004851520.043
determination of bilateral symmetryGO:00098552040.043
granulocyte migrationGO:0097530110.043
cell proliferationGO:0008283800.043
multicellular organismal signalingGO:0035637220.043
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.043
adherens junction organizationGO:003433240.043
response to drugGO:004249330.043
regulation of multicellular organismal developmentGO:20000262230.043
immune responseGO:0006955280.042
tissue remodelingGO:004877140.042
positive regulation of cellular processGO:00485222010.042
negative regulation of biological processGO:00485193040.042
Mouse
spermatid developmentGO:000728620.042
cellular amino acid metabolic processGO:000652070.042
regulation of cellular component movementGO:0051270550.042
myofibril assemblyGO:0030239480.042
regulation of mrna splicing via spliceosomeGO:004802430.041
positive regulation of macromolecule metabolic processGO:0010604930.041
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.040
ribonucleoside monophosphate catabolic processGO:000915840.040
positive regulation of mesenchymal cell proliferationGO:000205310.040
actin filament based processGO:0030029640.039
embryonic skeletal joint developmentGO:007249830.039
response to stressGO:00069502630.039
modification dependent protein catabolic processGO:001994130.038
cellular ketone metabolic processGO:0042180110.038
cellular component maintenanceGO:004395430.038
regulation of system processGO:0044057400.038
signal transductionGO:00071654550.038
regulation of syncytium formation by plasma membrane fusionGO:006014220.038
multicellular organismal reproductive processGO:0048609350.037
pigment cell differentiationGO:0050931380.037
stem cell developmentGO:0048864820.037
eye developmentGO:00016542770.037
multi organism processGO:00517041340.037
lateral line developmentGO:0048882660.037
Zebrafish
cell surface receptor signaling pathwayGO:00071663250.036
segmentationGO:0035282970.036
actin cytoskeleton organizationGO:0030036630.036
sensory system developmentGO:0048880760.036
Zebrafish
cell aggregationGO:009874330.036
regulation of cytokine productionGO:000181730.035
specification of symmetryGO:00097992040.035
mitochondrion organizationGO:000700540.035
response to fluid shear stressGO:003440520.035
regulation of cytoskeleton organizationGO:0051493110.035
regulation of signalingGO:00230512350.035
regulation of cellular amino acid metabolic processGO:000652100.035
positive regulation of cellular metabolic processGO:0031325940.034
maintenance of locationGO:005123540.034
growthGO:00400071740.034
rna localizationGO:000640340.034
heart morphogenesisGO:00030071560.033
response to woundingGO:00096111160.033
agingGO:000756820.033
metencephalon developmentGO:0022037270.032
regulation of chemotaxisGO:0050920180.032
hemopoiesisGO:00300971830.032
enzyme linked receptor protein signaling pathwayGO:00071671060.032
proteolysis involved in cellular protein catabolic processGO:005160330.032
semicircular canal developmentGO:0060872240.032
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.031
carboxylic acid metabolic processGO:0019752220.031
neuronal action potentialGO:0019228180.031
positive regulation of cellular amino acid metabolic processGO:004576400.030
determination of left right symmetryGO:00073681790.030
positive regulation of neurogenesisGO:0050769240.030
axonal defasciculationGO:000741420.029
tube closureGO:006060610.029
nucleobase containing compound biosynthetic processGO:00346542050.029
reactive oxygen species metabolic processGO:007259360.029
sister chromatid cohesionGO:000706220.029
connective tissue developmentGO:0061448990.029
regulation of blood vessel sizeGO:005088020.029
positive regulation of nucleobase containing compound metabolic processGO:0045935690.029
transmembrane transportGO:00550851200.028
positive regulation of muscle cell differentiationGO:005114910.028
regulation of rna metabolic processGO:00512522240.028
myeloid leukocyte migrationGO:0097529120.028
cellular response to chemical stimulusGO:00708871570.028
somite specificationGO:0001757120.028
developmental pigmentationGO:0048066480.028
muscle cell migrationGO:001481240.027
heart contractionGO:0060047710.027
notochord developmentGO:0030903540.027
regulation of alternative mrna splicing via spliceosomeGO:000038110.027
positive regulation of cell differentiationGO:0045597300.027
regulation of cardiac muscle tissue developmentGO:005502410.027
skeletal muscle thin filament assemblyGO:003024040.027
gastrulation with mouth forming secondGO:0001702440.026
regulation of bindingGO:005109830.026
multicellular organism reproductionGO:0032504350.026
muscle contractionGO:0006936180.026
regulation of purine nucleotide catabolic processGO:003312120.026
cell fate specificationGO:0001708680.026
neural crest formationGO:0014029140.026
dna templated transcription elongationGO:000635430.026
cognitionGO:005089010.026
cardiocyte differentiationGO:0035051440.025
positive regulation of macromolecule biosynthetic processGO:0010557590.025
regulation of tube sizeGO:003515020.025
regulation of neuron differentiationGO:0045664560.025
septum transversum developmentGO:000334340.025
negative regulation of biosynthetic processGO:0009890550.025
regulation of cell communicationGO:00106462320.025
heart developmentGO:00075073130.025
digestive tract morphogenesisGO:00485462310.025
actin filament based movementGO:003004810.025
regulation of collateral sprouting in absence of injuryGO:004869640.025
pigmentationGO:0043473850.025
positive regulation of rna biosynthetic processGO:1902680570.025
positive regulation of cellular amine metabolic processGO:003324000.025
mechanosensory lateral line system developmentGO:0048881490.024
Zebrafish
action potentialGO:0001508190.024
single organism localizationGO:19025782250.024
angiogenesisGO:00015251580.024
endoderm developmentGO:0007492490.024
reactive oxygen species biosynthetic processGO:190340910.024
hormone transportGO:000991420.024
microtubule organizing center organizationGO:003102310.024
ion transmembrane transportGO:0034220910.024
superoxide metabolic processGO:000680120.024
cellular component biogenesisGO:00440851780.024
neurotransmitter transportGO:000683620.024
regulation of signal transductionGO:00099662250.023
neuron projection regenerationGO:0031102160.023
regulation of organelle organizationGO:0033043290.023
heart processGO:0003015710.023
regulation of organ growthGO:004662030.023
positive regulation of protein kinase b signalingGO:005189710.023
regulation of sarcomere organizationGO:006029720.023
lipid storageGO:001991510.023
cardiac muscle tissue developmentGO:0048738480.023
positive regulation of striated muscle tissue developmentGO:004584410.022
negative regulation of metabolic processGO:0009892860.022
regulation of neurogenesisGO:0050767870.022
regulation of mrna processingGO:005068430.022
establishment of cell polarityGO:0030010180.022
cartilage developmentGO:0051216960.022
forebrain developmentGO:0030900960.022
regulation of localizationGO:00328791040.022
cytoplasm organizationGO:000702840.022
cardiac atrium developmentGO:000323040.022
establishment or maintenance of cell polarityGO:0007163290.022
regulation of circadian rhythmGO:004275240.022
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.022
protein metabolic processGO:00195381830.022
negative regulation of response to stimulusGO:00485851040.022
tissue regenerationGO:0042246740.022
regulation of peptidyl tyrosine phosphorylationGO:005073010.022
stem cell proliferationGO:007208940.022
cardiac muscle fiber developmentGO:004873930.022
regulation of protein bindingGO:004339330.022
myeloid cell homeostasisGO:0002262560.022
embryonic skeletal joint morphogenesisGO:006027230.022
macromolecule biosynthetic processGO:00090592270.022
transcription from rna polymerase ii promoterGO:0006366800.022
regulation of reproductive processGO:200024140.021
atp catabolic processGO:000620040.021
axon developmentGO:00615641660.021
cytokinesisGO:000091030.021
modification dependent macromolecule catabolic processGO:004363230.021
regulation of cell activationGO:005086510.021
positive regulation of rna metabolic processGO:0051254590.021
mesenchymal cell developmentGO:0014031780.021
stem cell maintenanceGO:001982740.021
biosynthetic processGO:00090582940.021
directional locomotionGO:003305810.020
anatomical structure arrangementGO:004853220.020
posterior lateral line system developmentGO:0048915460.020
Zebrafish
regulation of dendrite developmentGO:005077330.020
vasculature developmentGO:00019442780.020
regulation of synapse assemblyGO:005196330.020
regulation of nervous system developmentGO:0051960900.020
regulation of synapse organizationGO:005080730.020
regulation of heart contractionGO:0008016320.020
organonitrogen compound metabolic processGO:1901564740.020
skin developmentGO:0043588540.020
positive regulation of heart contractionGO:004582320.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.020
regulation of membrane potentialGO:0042391230.020
myelinationGO:0042552180.020
epithelial cell differentiationGO:00308551160.019
cardiac atrium morphogenesisGO:000320920.019
cellular protein catabolic processGO:004425740.019
neuroblast proliferationGO:000740520.019
regulation of multicellular organismal processGO:00512392770.019
extrinsic apoptotic signaling pathwayGO:009719130.019
regulation of striated muscle contractionGO:000694220.019
positive regulation of cell cycleGO:004578730.019
nucleocytoplasmic transportGO:000691340.019
ubiquitin dependent protein catabolic processGO:000651130.019
neutrophil homeostasisGO:000178010.019
positive regulation of transportGO:005105020.019
regulation of nucleoside metabolic processGO:000911820.019
positive regulation of blood circulationGO:190352420.019
regulation of cell migrationGO:0030334400.019
epibolyGO:0090504410.019
nuclear transportGO:005116940.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.019
axon ensheathmentGO:0008366180.019
camera type eye morphogenesisGO:00485931080.018
negative regulation of cell communicationGO:0010648960.018
single organism cell adhesionGO:0098602290.018
blood circulationGO:0008015870.018
sex determinationGO:000753010.018
response to carbohydrateGO:000974330.018
negative regulation of dna metabolic processGO:005105340.018
polarized epithelial cell differentiationGO:003085940.018
negative regulation of cytokine productionGO:000181810.018
outflow tract morphogenesisGO:000315110.018
cellular carbohydrate metabolic processGO:004426240.018
posterior lateral line developmentGO:0048916380.018
Zebrafish
regulation of cellular carbohydrate metabolic processGO:001067540.018
regulation of mitotic cell cycleGO:0007346250.017
organic acid metabolic processGO:0006082310.017
lymphoid lineage cell migrationGO:009753440.017
cellular protein modification processGO:00064641000.017
positive regulation of cytokine productionGO:000181920.017
cardiac muscle cell developmentGO:0055013200.017
inositol lipid mediated signalingGO:004801720.017
single organism reproductive processGO:0044702400.017
cell cycle arrestGO:000705010.017
response to oxygen containing compoundGO:1901700550.017
regulation of circadian sleep wake cycle sleepGO:004518710.017
digestive tract developmentGO:00485652650.017
regulation of photoreceptor cell differentiationGO:004653220.017
adaptive immune responseGO:000225050.017
regulation of heart growthGO:006042020.017
vasculogenesisGO:0001570410.017
cellular response to organic cyclic compoundGO:0071407380.017
transcription elongation from rna polymerase ii promoterGO:000636830.017
b cell activationGO:004211320.017
alternative mrna splicing via spliceosomeGO:000038010.017
regulation of cellular ketone metabolic processGO:001056570.017
oocyte anterior posterior axis specificationGO:000731440.016
negative regulation of cellular biosynthetic processGO:0031327550.016
regulation of gtp catabolic processGO:003312420.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.016
primary neural tube formationGO:001402010.016
developmental growthGO:00485891660.016
phosphorus metabolic processGO:00067931090.016
dorsal convergenceGO:0060030140.016
positive regulation of transcription dna templatedGO:0045893570.016
protein import into nucleusGO:000660630.016
regulation of stem cell differentiationGO:200073640.016
regulation of nucleotide catabolic processGO:003081120.016
regulation of dna replicationGO:000627530.016
determination of heart left right asymmetryGO:00613711170.016
intracellular mrna localizationGO:000829810.016
regulation of skeletal muscle cell differentiationGO:200101410.016
positive regulation of cell developmentGO:0010720250.016
positive regulation of map kinase activityGO:004340630.016
regulation of transcription from rna polymerase ii promoterGO:00063571140.016
positive regulation of carbohydrate metabolic processGO:004591310.016
synaptic growth at neuromuscular junctionGO:005112420.016
protein importGO:001703830.015
meiotic chromosome segregationGO:004513230.015
cellular protein metabolic processGO:00442671290.015
negative regulation of chemotaxisGO:005092240.015
cell death in response to oxidative stressGO:003647320.015
maternal determination of anterior posterior axis embryoGO:000835840.015
embryonic heart tube morphogenesisGO:00031431080.015
negative regulation of protein phosphorylationGO:000193340.015
determination of dorsal ventral asymmetryGO:0048262340.015
retina development in camera type eyeGO:00600411460.015
odontogenesis of dentin containing toothGO:004247510.015
regulation of blood circulationGO:1903522320.015
negative regulation of signalingGO:0023057960.015
regulation of carbohydrate metabolic processGO:000610940.015
cell cycleGO:0007049930.015
regulation of protein transportGO:005122330.015
neural crest cell differentiationGO:0014033720.015
muscle system processGO:0003012200.015
oxoacid metabolic processGO:0043436310.015
homeostasis of number of cellsGO:0048872620.015
hematopoietic stem cell differentiationGO:0060218200.015
mesoderm developmentGO:0007498880.015
positive regulation of cellular catabolic processGO:003133130.015
meiotic nuclear divisionGO:000712640.015
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124010.015
regulation of leukocyte migrationGO:000268580.015
regulation of blood pressureGO:000821710.015
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.014
negative regulation of secretion by cellGO:190353120.014
forebrain cell migrationGO:002188510.014
notochord morphogenesisGO:0048570170.014
membrane fusionGO:006102520.014
proteasomal protein catabolic processGO:001049820.014
positive regulation of dna templated transcription elongationGO:003278610.014
reproductive processGO:0022414400.014
positive regulation of striated muscle cell differentiationGO:005115510.014
branchiomotor neuron axon guidanceGO:002178510.014
glial cell migrationGO:000834730.014
positive regulation of stem cell proliferationGO:200064810.014
skeletal system morphogenesisGO:00487051020.014
protein phosphorylationGO:0006468470.014
peptidyl threonine phosphorylationGO:001810710.014
regulation of skeletal muscle tissue developmentGO:004864140.014
regulation of leukocyte chemotaxisGO:000268860.014
cellular response to biotic stimulusGO:007121630.014
regulation of response to external stimulusGO:0032101310.014
mrna metabolic processGO:0016071200.014
sexual reproductionGO:0019953360.014
positive regulation of muscle tissue developmentGO:190186310.014
sarcomerogenesisGO:004876940.014
muscle hypertrophyGO:001489620.014
deathGO:00162651210.014
single organism metabolic processGO:00447102170.014
larval heart developmentGO:000750820.014
positive regulation of biosynthetic processGO:0009891680.014
regulation of response to oxidative stressGO:190288220.013
negative regulation of nitrogen compound metabolic processGO:0051172590.013
regulation of striated muscle cell differentiationGO:005115360.013
mitotic cell cycleGO:0000278640.013
meiotic cell cycle processGO:190304630.013
positive regulation of transcription from rna polymerase ii promoterGO:0045944220.013
regulation of neurotransmitter secretionGO:004692810.013
ion transportGO:00068111140.013
cell projection morphogenesisGO:00488582440.013
response to monosaccharideGO:003428430.013
positive regulation of skeletal muscle tissue developmentGO:004864310.013
regulation of protein complex assemblyGO:004325430.013
ribosome assemblyGO:004225510.013
regulation of bmp signaling pathwayGO:0030510390.013
actomyosin structure organizationGO:0031032530.013
neurological system processGO:0050877620.013
mesenchymal cell proliferationGO:001046310.013

jam2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.037
muscular diseaseDOID:008000000.037
disease of anatomical entityDOID:700.037
muscle tissue diseaseDOID:6600.018
organ system cancerDOID:005068600.018
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018