Danio rerio

0 known processes

mdm4

transformed 3T3 cell double minute 4 homolog (mouse)

(Aliases: wu:fi33d10,wu:fa09h09)

mdm4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.124
cellular macromolecule metabolic processGO:00442603910.122
Human
negative regulation of biological processGO:00485193040.122
Human
regulation of metabolic processGO:00192223590.107
Human
nuclear transportGO:005116940.101
organic substance biosynthetic processGO:19015762890.091
Human
gene expressionGO:00104672520.083
Human
biosynthetic processGO:00090582940.080
Human
agingGO:000756820.077
regulation of primary metabolic processGO:00800903110.075
Human
regulation of mrna splicing via spliceosomeGO:004802430.070
negative regulation of cellular processGO:00485232830.067
Human
protein metabolic processGO:00195381830.065
Human
regulation of cellular metabolic processGO:00313233200.064
Human
regulation of nitrogen compound metabolic processGO:00511712510.063
Human
response to chemicalGO:00422213200.062
Human
aromatic compound biosynthetic processGO:00194382170.058
Human
single organism metabolic processGO:00447102170.056
regulation of biological qualityGO:00650082630.054
Human
transportGO:00068102200.054
regulation of developmental processGO:00507932470.052
maintenance of locationGO:005123540.052
regulation of macromolecule metabolic processGO:00602553170.052
Human
rna metabolic processGO:00160702190.052
Human
regulation of biosynthetic processGO:00098892500.051
Human
cell surface receptor signaling pathwayGO:00071663250.050
nucleic acid metabolic processGO:00903042440.050
Human
protein importGO:001703830.050
regulation of establishment of protein localizationGO:007020140.048
heterocycle metabolic processGO:00464832900.047
Human
regulation of response to stimulusGO:00485832690.047
establishment of localizationGO:00512342440.047
single organism organelle organizationGO:19025891990.047
cellular biosynthetic processGO:00442492860.046
Human
cellular nitrogen compound metabolic processGO:00346412900.045
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.044
cellular macromolecule biosynthetic processGO:00346452240.044
Human
negative regulation of cytoplasmic transportGO:190365020.044
regulation of circadian rhythmGO:004275240.043
regulation of gene expressionGO:00104682650.043
Human
multi organism processGO:00517041340.043
nitrogen compound metabolic processGO:00068073190.042
Human
cellular nitrogen compound biosynthetic processGO:00442712180.042
Human
regulation of nucleobase containing compound metabolic processGO:00192192500.041
Human
macromolecule biosynthetic processGO:00090592270.041
Human
stem cell maintenanceGO:001982740.041
regulation of signal transductionGO:00099662250.041
establishment of protein localization to organelleGO:007259440.041
cellular component assemblyGO:00226071700.041
Human
central nervous system developmentGO:00074173870.039
response to organic substanceGO:00100331530.039
nucleocytoplasmic transportGO:000691340.039
organic cyclic compound biosynthetic processGO:19013622230.039
Human
cellular protein metabolic processGO:00442671290.038
regulation of transcription dna templatedGO:00063552130.037
Human
morphogenesis of an epitheliumGO:00020093330.037
regulation of cellular amino acid metabolic processGO:000652100.037
single organism localizationGO:19025782250.036
regulation of protein transportGO:005122330.036
single organism transportGO:00447652060.036
camera type eye developmentGO:00430102220.036
cell migrationGO:00164772370.035
cellular component morphogenesisGO:00329893360.035
eye developmentGO:00016542770.035
neuron differentiationGO:00301823530.035
nuclear importGO:005117030.035
purine nucleoside monophosphate catabolic processGO:000912840.034
regulation of nucleic acid templated transcriptionGO:19035062130.034
Human
negative regulation of protein transportGO:005122430.034
locomotionGO:00400113130.033
protein import into nucleusGO:000660630.033
regulation of cell communicationGO:00106462320.033
proteasomal protein catabolic processGO:001049820.033
nucleic acid templated transcriptionGO:00976591810.033
Human
negative regulation of response to stimulusGO:00485851040.033
positive regulation of transportGO:005105020.033
protein targeting to nucleusGO:004474430.033
regulation of mrna processingGO:005068430.033
lipid storageGO:001991510.033
localization of cellGO:00516742440.032
response to stressGO:00069502630.032
Human
head developmentGO:00603223030.032
modification dependent macromolecule catabolic processGO:004363230.032
cell cycleGO:0007049930.032
Human
heterocycle biosynthetic processGO:00181302150.031
Human
rna biosynthetic processGO:00327741810.031
Human
rna localizationGO:000640340.030
centrosome organizationGO:005129710.030
cellular component movementGO:00069283350.030
nucleobase containing compound metabolic processGO:00061392740.030
Human
cellular protein catabolic processGO:004425740.029
regulation of cellular macromolecule biosynthetic processGO:20001122220.029
Human
cognitionGO:005089010.029
single organism nuclear importGO:190259330.028
amine metabolic processGO:000930820.028
germ line stem cell maintenanceGO:003071820.027
generation of neuronsGO:00486993850.027
organic acid metabolic processGO:0006082310.027
regulation of protein import into nucleusGO:004230620.027
phagocytosisGO:000690930.027
microtubule organizing center organizationGO:003102310.027
cellular response to endogenous stimulusGO:0071495680.027
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.026
Human
regulation of rna metabolic processGO:00512522240.026
Human
atp catabolic processGO:000620040.026
organelle organizationGO:00069962270.026
cellular amine metabolic processGO:004410620.026
regulation of signalingGO:00230512350.026
regulation of intracellular protein transportGO:003315730.026
ribonucleoside monophosphate catabolic processGO:000915840.026
carbohydrate biosynthetic processGO:001605110.025
regulation of stem cell differentiationGO:200073640.025
regulation of cytoplasmic transportGO:190364940.025
centrosome duplicationGO:005129810.025
regulation of cellular ketone metabolic processGO:001056570.025
cortical cytoskeleton organizationGO:003086510.025
cellular ketone metabolic processGO:0042180110.025
chordate embryonic developmentGO:00430092710.025
regulation of alternative mrna splicing via spliceosomeGO:000038110.025
digestive tract developmentGO:00485652650.025
regulation of cell differentiationGO:00455951420.024
stem cell proliferationGO:007208940.024
system processGO:00030081850.024
sister chromatid cohesionGO:000706220.024
transcription dna templatedGO:00063511810.024
Human
oxoacid metabolic processGO:0043436310.024
digestive system developmentGO:00551232890.024
extrinsic apoptotic signaling pathwayGO:009719130.024
negative regulation of biosynthetic processGO:0009890550.023
Human
cellular amino acid metabolic processGO:000652070.023
cytokinesisGO:000091030.023
regulation of multicellular organism growthGO:004001440.023
camera type eye morphogenesisGO:00485931080.023
regulation of protein targetingGO:190353320.023
embryo development ending in birth or egg hatchingGO:00097922710.023
regulation of macromolecule biosynthetic processGO:00105562250.023
Human
regulation of cellular biosynthetic processGO:00313262450.023
Human
ameboidal type cell migrationGO:00016671430.023
protein modification processGO:00362111000.022
alternative mrna splicing via spliceosomeGO:000038010.022
stem cell divisionGO:001714510.022
negative regulation of intracellular protein transportGO:009031730.022
hormone transportGO:000991420.022
regulation of stem cell proliferationGO:007209120.022
carboxylic acid metabolic processGO:0019752220.022
adult behaviorGO:003053420.022
brain developmentGO:00074202930.022
cellular localizationGO:0051641970.022
negative regulation of protein phosphorylationGO:000193340.022
carbohydrate homeostasisGO:003350010.022
tube morphogenesisGO:00352393490.022
internal peptidyl lysine acetylationGO:001839320.022
chemosensory behaviorGO:000763510.021
positive regulation of cellular catabolic processGO:003133130.021
cellular aromatic compound metabolic processGO:00067252950.021
Human
centrosome cycleGO:000709810.021
translational initiationGO:000641330.021
organic cyclic compound metabolic processGO:19013603010.021
Human
meiotic cell cycle processGO:190304630.021
nucleoside monophosphate catabolic processGO:000912540.021
enzyme linked receptor protein signaling pathwayGO:00071671060.021
epithelial cell morphogenesisGO:000338220.021
intracellular signal transductionGO:0035556850.021
Human
protein localization to nucleusGO:003450430.021
regulation of metal ion transportGO:001095940.021
cytoskeleton dependent cytokinesisGO:006164030.021
regulation of multicellular organismal developmentGO:20000262230.021
protein acylationGO:004354330.021
muscle structure developmentGO:00610611960.021
multicellular organismal reproductive processGO:0048609350.021
sensory organ developmentGO:00074233930.021
response to drugGO:004249330.020
internal protein amino acid acetylationGO:000647520.020
negative regulation of cellular biosynthetic processGO:0031327550.020
Human
modification dependent protein catabolic processGO:001994130.020
organelle assemblyGO:00709251100.020
blood vessel developmentGO:00015682460.020
immune system processGO:00023762410.020
guanosine containing compound metabolic processGO:190106840.020
erk1 and erk2 cascadeGO:007037140.020
meiotic nuclear divisionGO:000712640.020
nucleic acid transportGO:005065720.020
cell projection organizationGO:00300302840.020
establishment of rna localizationGO:005123630.020
positive regulation of biological processGO:00485182530.020
regulation of protein localization to nucleusGO:190018020.020
synaptic growth at neuromuscular junctionGO:005112420.020
sensory organ morphogenesisGO:00905962000.019
establishment of localization in cellGO:0051649770.019
negative regulation of catabolic processGO:000989530.019
Human
macromolecule modificationGO:00434121110.019
response to hexoseGO:000974630.019
mitochondrion organizationGO:000700540.019
negative regulation of metabolic processGO:0009892860.019
Human
negative regulation of developmental processGO:0051093650.019
negative regulation of ras protein signal transductionGO:004658010.019
regulation of cell shapeGO:000836010.019
regulation of cellular amine metabolic processGO:003323800.019
regulation of synaptic plasticityGO:004816710.019
regulation of synapse organizationGO:005080730.019
response to monosaccharideGO:003428430.019
protein dephosphorylationGO:000647030.019
positive regulation of erk1 and erk2 cascadeGO:007037420.019
positive regulation of catabolic processGO:000989640.019
regulation of carbohydrate metabolic processGO:000610940.019
nucleobase containing compound biosynthetic processGO:00346542050.019
Human
regulation of wound healingGO:006104120.018
cellular component biogenesisGO:00440851780.018
Human
sexual reproductionGO:0019953360.018
blood vessel morphogenesisGO:00485142160.018
cell motilityGO:00488702440.018
regulation of synapse assemblyGO:005196330.018
multicellular organism growthGO:003526440.018
neuron developmentGO:00486662620.018
proteolysis involved in cellular protein catabolic processGO:005160330.018
cell morphogenesisGO:00009022890.018
hematopoietic or lymphoid organ developmentGO:00485341910.017
rna export from nucleusGO:000640510.017
mitotic cell cycleGO:0000278640.017
stem cell differentiationGO:00488631170.017
regulation of i kappab kinase nf kappab signalingGO:004312240.017
regulation of synaptic growth at neuromuscular junctionGO:000858210.017
ubiquitin dependent protein catabolic processGO:000651130.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
negative regulation of protein import into nucleusGO:004230820.017
signal transductionGO:00071654550.017
Human
negative regulation of chromosome organizationGO:200125110.017
regulation of sodium ion transportGO:000202820.017
regulation of rna biosynthetic processGO:20011412130.017
Human
neuroblast proliferationGO:000740520.017
i kappab kinase nf kappab signalingGO:000724940.017
negative regulation of macromolecule metabolic processGO:0010605760.017
Human
angiogenesisGO:00015251580.017
regulation of erk1 and erk2 cascadeGO:007037240.017
mrna transportGO:005102820.017
regulation of cytokine productionGO:000181730.016
cell proliferationGO:0008283800.016
Human
regulation of cell activationGO:005086510.016
regulation of microtubule cytoskeleton organizationGO:007050730.016
response to carbohydrateGO:000974330.016
regulation of reproductive processGO:200024140.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
locomotor rhythmGO:004547530.016
vasculature developmentGO:00019442780.016
cell cycle g1 s phase transitionGO:004484310.016
negative regulation of kinase activityGO:003367340.016
hormone secretionGO:004687920.016
negative regulation of gene expressionGO:0010629650.016
Human
gtp catabolic processGO:000618420.016
positive regulation of cellular amine metabolic processGO:003324000.016
neurotransmitter transportGO:000683620.016
cell part morphogenesisGO:00329902460.016
regionalizationGO:00030022740.016
cellular response to organic substanceGO:00713101050.016
tube closureGO:006060610.016
regulation of dendrite developmentGO:005077330.015
retina development in camera type eyeGO:00600411460.015
transcription from rna polymerase ii promoterGO:0006366800.015
Human
negative regulation of cell differentiationGO:0045596460.015
compound eye developmentGO:004874920.015
response to uvGO:000941130.015
nucleobase containing compound transportGO:001593120.015
cellular carbohydrate metabolic processGO:004426240.015
positive regulation of cellular component biogenesisGO:004408930.015
primary neural tube formationGO:001402010.015
positive regulation of gtp catabolic processGO:003312610.015
organonitrogen compound metabolic processGO:1901564740.015
regulation of nucleotide catabolic processGO:003081120.015
negative regulation of nucleocytoplasmic transportGO:004682320.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
Human
cortical actin cytoskeleton organizationGO:003086610.015
positive regulation of cell cycleGO:004578730.015
regulation of organelle assemblyGO:190211540.015
immune system developmentGO:00025201910.015
glial cell proliferationGO:001400940.015
cellular protein modification processGO:00064641000.015
b cell activationGO:004211320.014
developmental programmed cell deathGO:001062340.014
autophagyGO:000691440.014
response to glucoseGO:000974930.014
response to hormoneGO:0009725480.014
regulation of purine nucleotide catabolic processGO:003312120.014
secondary metabolic processGO:001974830.014
positive regulation of apoptotic signaling pathwayGO:200123510.014
negative regulation of cytokine productionGO:000181810.014
cytoskeleton organizationGO:0007010960.014
regulation of protein ubiquitinationGO:003139630.014
aorta developmentGO:003590440.014
establishment of synaptic vesicle localizationGO:009748010.014
medulla oblongata developmentGO:002155040.014
purine ribonucleoside monophosphate catabolic processGO:000916940.014
positive regulation of gtpase activityGO:004354710.014
regulation of cell developmentGO:00602841000.014
negative regulation of intracellular transportGO:003238730.014
response to abiotic stimulusGO:00096281220.014
Human
hemopoiesisGO:00300971830.014
regulation of nucleocytoplasmic transportGO:004682220.014
cell projection morphogenesisGO:00488582440.014
small gtpase mediated signal transductionGO:000726480.014
negative regulation of multicellular organismal processGO:0051241690.014
eye morphogenesisGO:00485921440.014
homeostatic processGO:00425921420.014
multicellular organism reproductionGO:0032504350.014
positive regulation of dna metabolic processGO:005105410.014
cell cycle processGO:0022402530.014
Human
dorsal ventral pattern formationGO:00099531250.014
g1 s transition of mitotic cell cycleGO:000008210.014
positive regulation of striated muscle tissue developmentGO:004584410.014
axonogenesisGO:00074091520.014
apoptotic processGO:00069151160.014
negative regulation of protein kinase activityGO:000646940.014
phosphate containing compound metabolic processGO:00067961080.014
peptidyl lysine acetylationGO:001839420.014
response to amino acidGO:004320020.014
striated muscle cell differentiationGO:00511461290.013
embryonic organ developmentGO:00485683810.013
regulation of jak stat cascadeGO:004642530.013
protein localization to plasma membraneGO:007265910.013
negative regulation of small gtpase mediated signal transductionGO:005105810.013
guanosine containing compound catabolic processGO:190106920.013
organic substance transportGO:0071702580.013
regulation of calcium ion transportGO:005192420.013
muscle organ developmentGO:00075171010.013
protein acetylationGO:000647320.013
microtubule based processGO:0007017600.013
positive regulation of stem cell proliferationGO:200064810.013
response to glucocorticoidGO:005138410.013
cellular response to external stimulusGO:007149620.013
regulation of multicellular organismal processGO:00512392770.013
phosphorus metabolic processGO:00067931090.013
programmed cell deathGO:00125011190.013
positive regulation of cytoskeleton organizationGO:005149530.013
negative regulation of mapk cascadeGO:004340940.013
positive regulation of lymphocyte mediated immunityGO:000270810.013
regulation of nucleoside metabolic processGO:000911820.013
gtp metabolic processGO:004603940.013
apoptotic process involved in developmentGO:190274220.013
peptidyl threonine phosphorylationGO:001810710.013
rna 3 end processingGO:003112320.012
positive regulation of map kinase activityGO:004340630.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
Human
regulation of protein modification by small protein conjugation or removalGO:190332030.012
regulation of protein complex assemblyGO:004325430.012
anterior posterior pattern specificationGO:00099521520.012
cellular amide metabolic processGO:004360340.012
meiosis iGO:000712710.012
response to endogenous stimulusGO:0009719830.012
spindle assemblyGO:005122520.012
cellular response to chemical stimulusGO:00708871570.012
Human
cell substrate adhesionGO:003158940.012
small molecule metabolic processGO:0044281770.012
cellular response to extracellular stimulusGO:003166820.012
phosphorylationGO:0016310690.012
peptidyl serine modificationGO:001820920.012
somatic muscle developmentGO:000752540.012
negative regulation of nuclear divisionGO:005178430.012
calcium mediated signalingGO:001972220.012
cellular response to nutrient levelsGO:003166920.012
response to corticosteroidGO:003196010.012
negative regulation of protein localization to nucleusGO:190018120.012
protein homooligomerizationGO:005126030.012
lymphocyte proliferationGO:004665110.012
negative regulation of reproductive processGO:200024230.012
positive regulation of chromatin modificationGO:190331010.012
oocyte anterior posterior axis specificationGO:000731440.012
golgi vesicle transportGO:004819330.012
pole plasm assemblyGO:000731540.012
intracellular mrna localizationGO:000829810.012
positive regulation of nucleoside metabolic processGO:004597910.012
production of molecular mediator of immune responseGO:000244020.012
positive regulation of cell activationGO:005086710.012
amino acid transportGO:000686520.012
positive regulation of nucleotide catabolic processGO:003081310.012
reproductionGO:0000003400.011
regulation of translational initiationGO:000644610.011
multi organism reproductive processGO:0044703360.011
organelle fusionGO:004828430.011
mitotic cytokinesisGO:000028130.011
regulation of systemic arterial blood pressureGO:000307310.011
phagocytosis engulfmentGO:000691110.011
hepaticobiliary system developmentGO:0061008980.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
regulation of localizationGO:00328791040.011
negative regulation of cellular metabolic processGO:0031324770.011
Human
regulation of hormone secretionGO:004688320.011
regulation of gtp catabolic processGO:003312420.011
negative regulation of macromolecule biosynthetic processGO:0010558480.011
Human
cellular response to starvationGO:000926710.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
spermatid differentiationGO:004851520.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of oocyte developmentGO:006028130.011
regulation of reactive oxygen species metabolic processGO:200037720.011
peptidyl threonine modificationGO:001821010.011
glucose homeostasisGO:004259310.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
single organism membrane fusionGO:004480120.011
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.011
embryonic skeletal system developmentGO:0048706970.011
regulation of neural precursor cell proliferationGO:200017730.011
regulation of chromosome segregationGO:005198310.011
cell migration involved in gastrulationGO:0042074790.011
peptide transportGO:001583310.011
protein heterooligomerizationGO:005129110.011
regulation of carbohydrate biosynthetic processGO:004325510.011
gastrulationGO:00073692080.011
endocrine hormone secretionGO:006098620.011
hindbrain developmentGO:0030902910.011
response to woundingGO:00096111160.011
response to external stimulusGO:00096052640.011
digestive tract morphogenesisGO:00485462310.011
dna templated transcription elongationGO:000635430.011
regulation of transporter activityGO:003240920.011
negative regulation of synapse assemblyGO:005196420.011
regulation of phosphorus metabolic processGO:0051174430.011
development of primary female sexual characteristicsGO:004654540.011
neuron projection developmentGO:00311751800.011
developmental growthGO:00485891660.011
rna transportGO:005065820.011
histone phosphorylationGO:001657220.010
positive regulation of cytosolic calcium ion concentrationGO:000720440.010
establishment of endothelial barrierGO:006102830.010
embryonic skeletal joint developmentGO:007249830.010
sex determinationGO:000753010.010
positive regulation of immune effector processGO:000269930.010
muscle cell developmentGO:00550011150.010
regulation of gtpase activityGO:004308720.010
neuron neuron synaptic transmissionGO:000727010.010
neurotransmitter secretionGO:000726920.010
stem cell developmentGO:0048864820.010
female sex differentiationGO:004666040.010
membrane invaginationGO:001032410.010
lipid homeostasisGO:005508830.010
positive regulation of translationGO:004572710.010
positive regulation of muscle organ developmentGO:004863610.010
entrainment of circadian clockGO:000964920.010
cell matrix adhesionGO:000716040.010
single organism biosynthetic processGO:0044711710.010
regulation of receptor activityGO:001046920.010
positive regulation of epithelial cell proliferationGO:005067910.010
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018440.010
chromosome organizationGO:0051276310.010
negative regulation of gliogenesisGO:001401410.010
axon developmentGO:00615641660.010
positive regulation of muscle cell differentiationGO:005114910.010
regulation of blood pressureGO:000821710.010

mdm4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.020
musculoskeletal system diseaseDOID:1700.019
disease of metabolismDOID:001466700.019
cancerDOID:16200.015
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
connective tissue diseaseDOID:6500.011