Danio rerio

29 known processes

hsd17b1

hydroxysteroid (17-beta) dehydrogenase 1

(Aliases: zfHSD17B1)

hsd17b1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of endocrine processGO:004406020.665
endocrine hormone secretionGO:006098620.639
regulation of gonadotropin secretionGO:003227610.569
ovulation cycleGO:004269820.531
steroid hormone secretionGO:003592910.452
regulation of hormone secretionGO:004688320.364
regulation of extrinsic apoptotic signaling pathwayGO:200123630.348
regulation of metal ion transportGO:001095940.341
regulation of sodium ion transportGO:000202820.325
endocrine processGO:005088620.322
establishment of endothelial barrierGO:006102830.308
cognitionGO:005089010.302
metal ion transportGO:0030001580.262
gonadotropin secretionGO:003227410.235
tube morphogenesisGO:00352393490.228
cation transportGO:0006812810.227
development of primary female sexual characteristicsGO:004654540.222
gastrulation with mouth forming secondGO:0001702440.210
morphogenesis of an epitheliumGO:00020093330.206
gastrulationGO:00073692080.202
female gonad developmentGO:000858540.200
regulation of biological qualityGO:00650082630.190
digestive tract developmentGO:00485652650.188
organic substance biosynthetic processGO:19015762890.184
digestive system developmentGO:00551232890.183
single organism localizationGO:19025782250.182
transportGO:00068102200.182
lateral line developmentGO:0048882660.176
digestive tract morphogenesisGO:00485462310.173
female sex differentiationGO:004666040.170
regulation of system processGO:0044057400.164
cellular response to lipopolysaccharideGO:007122230.159
ovulation cycle processGO:002260220.157
cyclic purine nucleotide metabolic processGO:0052652180.148
nitrogen compound metabolic processGO:00068073190.140
organic cyclic compound metabolic processGO:19013603010.140
regulation of sequestering of calcium ionGO:005128240.138
ion transportGO:00068111140.137
neuromast developmentGO:0048884460.136
response to drugGO:004249330.136
system processGO:00030081850.135
biosynthetic processGO:00090582940.132
single organism transportGO:00447652060.128
extrinsic apoptotic signaling pathwayGO:009719130.127
establishment of localizationGO:00512342440.125
regulation of localizationGO:00328791040.123
response to antibioticGO:004667710.118
hormone transportGO:000991420.117
response to chemicalGO:00422213200.116
Rat
response to organic substanceGO:00100331530.114
nucleobase containing compound biosynthetic processGO:00346542050.114
cellular biosynthetic processGO:00442492860.112
epithelial cell differentiationGO:00308551160.111
regulation of cellular biosynthetic processGO:00313262450.109
regulation of lyase activityGO:0051339120.108
organic acid metabolic processGO:0006082310.108
morphogenesis of an epithelial sheetGO:0002011490.108
positive regulation of myeloid cell differentiationGO:004563920.107
agingGO:000756820.106
ovarian follicle developmentGO:000154120.106
signal transduction in absence of ligandGO:003803410.105
regulation of primary metabolic processGO:00800903110.104
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.101
hormone secretionGO:004687920.101
cellular nitrogen compound metabolic processGO:00346412900.101
regulation of metabolic processGO:00192223590.098
aromatic compound biosynthetic processGO:00194382170.096
establishment of protein localization to organelleGO:007259440.093
alcohol biosynthetic processGO:004616520.092
Rat
sensory organ developmentGO:00074233930.089
sequestering of metal ionGO:005123830.088
lateral line system developmentGO:0048925760.088
regulation of cytoplasmic transportGO:190364940.087
apical junction assemblyGO:004329710.087
organic cyclic compound biosynthetic processGO:19013622230.085
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.085
polyol metabolic processGO:001975110.083
maintenance of locationGO:005123540.082
epibolyGO:0090504410.082
sequestering of calcium ionGO:005120830.077
small molecule metabolic processGO:0044281770.077
Rat
single organism biosynthetic processGO:0044711710.077
regulation of biosynthetic processGO:00098892500.074
positive regulation of transportGO:005105020.073
response to xenobiotic stimulusGO:0009410450.072
embryo development ending in birth or egg hatchingGO:00097922710.072
tissue remodelingGO:004877140.071
single organism metabolic processGO:00447102170.071
cellular aromatic compound metabolic processGO:00067252950.071
amine metabolic processGO:000930820.071
positive regulation of nucleotide biosynthetic processGO:003081080.070
regulation of nucleotide biosynthetic processGO:0030808150.070
rhythmic processGO:0048511210.069
oxoacid metabolic processGO:0043436310.069
regulation of ion transportGO:0043269220.068
regulation of cellular metabolic processGO:00313233200.068
positive regulation of biological processGO:00485182530.066
neurological system processGO:0050877620.066
brain developmentGO:00074202930.065
regulation of signal transductionGO:00099662250.065
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.065
homeostatic processGO:00425921420.065
response to carbohydrateGO:000974330.064
regulation of cyclic nucleotide biosynthetic processGO:0030802150.063
positive regulation of cellular processGO:00485222010.063
response to glucocorticoidGO:005138410.062
negative regulation of sequestering of calcium ionGO:005128340.062
regulation of erythrocyte differentiationGO:004564620.062
organonitrogen compound metabolic processGO:1901564740.062
regulation of transportGO:0051049450.062
immune system developmentGO:00025201910.062
regulation of response to stimulusGO:00485832690.062
regulation of blood pressureGO:000821710.061
proteolysis involved in cellular protein catabolic processGO:005160330.060
heterocycle metabolic processGO:00464832900.060
positive regulation of camp biosynthetic processGO:003081920.060
epithelial cell developmentGO:0002064420.060
cell surface receptor signaling pathwayGO:00071663250.059
response to stressGO:00069502630.059
lipid metabolic processGO:0006629520.059
positive regulation of cellular amino acid metabolic processGO:004576400.059
signal transductionGO:00071654550.059
nucleobase containing compound metabolic processGO:00061392740.058
cellular response to antibioticGO:007123610.058
heterocycle biosynthetic processGO:00181302150.058
negative regulation of secretionGO:005104820.057
head developmentGO:00603223030.057
sensory system developmentGO:0048880760.057
regulation of developmental processGO:00507932470.057
cellular amine metabolic processGO:004410620.056
negative regulation of biological processGO:00485193040.056
regulation of hormone levelsGO:0010817210.055
regulation of multicellular organismal developmentGO:20000262230.055
larval developmentGO:000216420.054
inositol phosphate metabolic processGO:004364710.054
multicellular organism growthGO:003526440.053
vacuolar transportGO:000703420.053
positive regulation of gene expressionGO:0010628710.053
secondary metabolic processGO:001974830.052
epiboly involved in gastrulation with mouth forming secondGO:0055113350.052
cellular response to endogenous stimulusGO:0071495680.051
response to hormoneGO:0009725480.051
cellular response to organic substanceGO:00713101050.051
regulation of cellular carbohydrate metabolic processGO:001067540.051
negative regulation of cellular processGO:00485232830.050
xenobiotic metabolic processGO:000680540.049
regulation of nitrogen compound metabolic processGO:00511712510.049
regulation of cellular amine metabolic processGO:003323800.049
rna metabolic processGO:00160702190.049
calcium ion transport into cytosolGO:006040230.049
cellular component movementGO:00069283350.049
hematopoietic or lymphoid organ developmentGO:00485341910.048
response to endogenous stimulusGO:0009719830.048
positive regulation of purine nucleotide biosynthetic processGO:190037380.048
mitochondrion organizationGO:000700540.047
ribose phosphate biosynthetic processGO:0046390200.047
regulation of blood vessel sizeGO:005088020.046
regulation of multicellular organismal processGO:00512392770.046
negative regulation of hormone secretionGO:004688820.045
endothelium developmentGO:0003158250.045
lipid biosynthetic processGO:0008610220.045
response to bacteriumGO:0009617580.045
immune system processGO:00023762410.044
nucleic acid metabolic processGO:00903042440.044
cell cell signalingGO:0007267520.044
response to monosaccharideGO:003428430.044
locomotionGO:00400113130.044
regulation of transcription dna templatedGO:00063552130.044
cellular response to chemical stimulusGO:00708871570.044
Rat
regulation of calcium ion transportGO:005192420.043
cell cycle g1 s phase transitionGO:004484310.043
regulation of purine nucleotide biosynthetic processGO:1900371150.043
regulation of cyclase activityGO:0031279120.043
cell cycle arrestGO:000705010.043
cellular ketone metabolic processGO:0042180110.043
Rat
ubiquitin dependent protein catabolic processGO:000651130.042
endothelial cell developmentGO:0001885120.042
cytosolic calcium ion transportGO:006040130.042
response to corticosteroidGO:003196010.042
carboxylic acid metabolic processGO:0019752220.041
erythrocyte homeostasisGO:0034101550.041
protein targeting to vacuoleGO:000662310.041
steroid biosynthetic processGO:000669450.041
diterpenoid metabolic processGO:0016101150.041
pronephros developmentGO:0048793690.041
response to organic cyclic compoundGO:0014070510.040
modification dependent protein catabolic processGO:001994130.040
long chain fatty acid metabolic processGO:000167610.039
organic hydroxy compound biosynthetic processGO:190161760.039
Rat
response to external stimulusGO:00096052640.039
central nervous system developmentGO:00074173870.039
regulation of carbohydrate metabolic processGO:000610940.039
transcription from rna polymerase ii promoterGO:0006366800.038
cellular component morphogenesisGO:00329893360.038
cell cell adhesion via plasma membrane adhesion moleculesGO:009874260.038
circulatory system processGO:0003013870.038
regulation of signalingGO:00230512350.038
cellular carbohydrate metabolic processGO:004426240.038
cellular response to molecule of bacterial originGO:007121930.038
macromolecule biosynthetic processGO:00090592270.038
detection of external stimulusGO:0009581240.038
response to vitaminGO:003327330.038
positive regulation of cytosolic calcium ion concentrationGO:000720440.037
transcription dna templatedGO:00063511810.037
regionalizationGO:00030022740.037
regulation of muscle contractionGO:000693730.037
positive regulation of secretionGO:005104710.036
positive regulation of apoptotic signaling pathwayGO:200123510.036
multi organism processGO:00517041340.036
calcium independent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633810.035
nuclear transportGO:005116940.035
regulation of reproductive processGO:200024140.035
modification dependent macromolecule catabolic processGO:004363230.035
regulation of tube sizeGO:003515020.035
protein importGO:001703830.034
regulation of cell differentiationGO:00455951420.034
fin regenerationGO:0031101510.034
carbohydrate derivative metabolic processGO:1901135610.034
protein localization to nucleusGO:003450430.034
determination of bilateral symmetryGO:00098552040.034
regulation of peptidyl tyrosine phosphorylationGO:005073010.034
positive regulation of rna metabolic processGO:0051254590.034
cellular amino acid metabolic processGO:000652070.034
regulation of protein polymerizationGO:003227120.034
organelle organizationGO:00069962270.034
cell cell adhesionGO:009860960.033
organonitrogen compound biosynthetic processGO:1901566470.033
phospholipase c activating g protein coupled receptor signaling pathwayGO:000720020.033
intracellular signal transductionGO:0035556850.033
protein localizationGO:0008104400.033
developmental growthGO:00485891660.033
neurotransmitter transportGO:000683620.033
regulation of rna metabolic processGO:00512522240.033
protein localization to vacuoleGO:007266510.033
mesenchymal cell developmentGO:0014031780.033
sodium ion transportGO:0006814240.033
cellular response to organic cyclic compoundGO:0071407380.033
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.032
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.032
phosphatidylinositol mediated signalingGO:004801520.032
regulation of macromolecule metabolic processGO:00602553170.032
epithelial tube morphogenesisGO:00605621480.032
lipid storageGO:001991510.032
positive regulation of cellular amine metabolic processGO:003324000.032
regulation of protein transportGO:005122330.032
nucleocytoplasmic transportGO:000691340.032
cell migrationGO:00164772370.032
fatty acid biosynthetic processGO:000663340.032
biological adhesionGO:0022610400.032
regulation of neural precursor cell proliferationGO:200017730.031
regulation of rna biosynthetic processGO:20011412130.031
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.031
response to external biotic stimulusGO:0043207970.031
single organism nuclear importGO:190259330.031
response to alkaloidGO:004327920.031
cellular protein catabolic processGO:004425740.031
long chain fatty acid transportGO:001590910.031
gene expressionGO:00104672520.031
hormone biosynthetic processGO:004244630.031
gland developmentGO:00487321430.031
response to steroid hormoneGO:0048545350.031
regulation of cellular amino acid metabolic processGO:000652100.031
erythrocyte differentiationGO:0030218540.031
establishment of localization in cellGO:0051649770.031
enzyme linked receptor protein signaling pathwayGO:00071671060.031
regulation of cell communicationGO:00106462320.030
regulation of cyclic nucleotide metabolic processGO:0030799150.030
positive regulation of biosynthetic processGO:0009891680.030
regulation of nucleobase containing compound metabolic processGO:00192192500.030
water homeostasisGO:003010440.030
blood vessel morphogenesisGO:00485142160.030
regulation of systemic arterial blood pressureGO:000307310.030
cellular localizationGO:0051641970.030
positive regulation of cellular metabolic processGO:0031325940.030
cell morphogenesisGO:00009022890.030
positive regulation of camp metabolic processGO:003081620.030
pathway restricted smad protein phosphorylationGO:006038910.029
cell proliferationGO:0008283800.029
positive regulation of lyase activityGO:005134960.029
endosomal transportGO:001619720.029
cellular nitrogen compound biosynthetic processGO:00442712180.029
positive regulation of response to stimulusGO:0048584800.029
tissue regenerationGO:0042246740.029
protein import into nucleusGO:000660630.029
sensory perception of painGO:001923310.029
meiotic nuclear divisionGO:000712640.028
cellular component biogenesisGO:00440851780.028
endoderm formationGO:0001706290.028
g1 s transition of mitotic cell cycleGO:000008210.028
formation of primary germ layerGO:0001704620.028
cellular response to biotic stimulusGO:007121630.028
positive regulation of cell communicationGO:0010647560.028
hormone metabolic processGO:0042445190.028
g protein coupled receptor signaling pathwayGO:0007186740.027
rna biosynthetic processGO:00327741810.027
regulation of nucleic acid templated transcriptionGO:19035062130.027
vasculature developmentGO:00019442780.027
inositol lipid mediated signalingGO:004801720.027
positive regulation of nucleobase containing compound metabolic processGO:0045935690.027
sensory perceptionGO:0007600390.027
detection of abiotic stimulusGO:0009582240.027
response to ketoneGO:190165410.027
response to glucoseGO:000974930.027
regulation of protein targetingGO:190353320.027
toxin metabolic processGO:000940410.027
regulation of protein complex assemblyGO:004325430.027
carbohydrate derivative biosynthetic processGO:1901137430.027
cellular protein metabolic processGO:00442671290.027
regulation of cellular macromolecule biosynthetic processGO:20001122220.027
regulation of protein import into nucleusGO:004230620.027
positive regulation of signalingGO:0023056560.026
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.026
regulation of intracellular protein transportGO:003315730.026
cell projection morphogenesisGO:00488582440.026
cellular response to lipidGO:0071396390.026
cartilage developmentGO:0051216960.026
stem cell maintenanceGO:001982740.026
segmentationGO:0035282970.026
blood vessel developmentGO:00015682460.026
cell part morphogenesisGO:00329902460.026
phosphatidylinositol 3 kinase signalingGO:001406520.026
regulation of cellular ketone metabolic processGO:001056570.026
neurotransmitter secretionGO:000726920.026
hindbrain developmentGO:0030902910.026
regulation of homeostatic processGO:003284490.026
determination of left right symmetryGO:00073681790.025
protein polymerizationGO:005125840.025
adult behaviorGO:003053420.025
detection of mechanical stimulus involved in sensory perceptionGO:0050974110.025
protein targeting to nucleusGO:004474430.025
carbohydrate biosynthetic processGO:001605110.025
negative regulation of peptidase activityGO:0010466100.025
cellular macromolecule biosynthetic processGO:00346452240.025
nuclear importGO:005117030.025
regulation of cell shapeGO:000836010.025
regulation of nucleocytoplasmic transportGO:004682220.024
cellular response to hormone stimulusGO:0032870390.024
somite developmentGO:0061053960.024
detection of stimulus involved in sensory perceptionGO:0050906210.024
organophosphate biosynthetic processGO:0090407230.024
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.024
positive regulation of metabolic processGO:00098931080.024
response to oxygen containing compoundGO:1901700550.024
chordate embryonic developmentGO:00430092710.024
glucocorticoid metabolic processGO:000821120.024
response to nutrientGO:000758430.024
response to lipidGO:0033993600.024
fatty acid transportGO:001590810.024
neuron differentiationGO:00301823530.024
positive regulation of blood circulationGO:190352420.024
regulation of catalytic activityGO:0050790550.023
positive regulation of carbohydrate metabolic processGO:004591310.023
estrogen metabolic processGO:000821020.023
blood circulationGO:0008015870.023
androgen metabolic processGO:000820920.023
positive regulation of cyclic nucleotide metabolic processGO:003080180.023
regulation of macromolecule biosynthetic processGO:00105562250.023
multicellular organism reproductionGO:0032504350.023
embryonic skeletal system developmentGO:0048706970.023
endothelial cell differentiationGO:0045446200.022
reproductive processGO:0022414400.022
calcium mediated signalingGO:001972220.022
positive regulation of cellular component biogenesisGO:004408930.022
nucleic acid templated transcriptionGO:00976591810.022
phosphorus metabolic processGO:00067931090.022
wound healingGO:0042060900.022
erk1 and erk2 cascadeGO:007037140.022
positive regulation of nitrogen compound metabolic processGO:0051173690.022
regulation of erk1 and erk2 cascadeGO:007037240.022
myeloid cell homeostasisGO:0002262560.022
cellular protein modification processGO:00064641000.022
axonogenesisGO:00074091520.022
defense responseGO:0006952470.022
neuron projection developmentGO:00311751800.022
positive regulation of rna biosynthetic processGO:1902680570.022
protein acetylationGO:000647320.022
cellular macromolecule metabolic processGO:00442603910.022
purine nucleotide biosynthetic processGO:0006164200.021
single organism organelle organizationGO:19025891990.021
hematopoietic progenitor cell differentiationGO:0002244230.021
anterior posterior pattern specificationGO:00099521520.021
negative regulation of mapk cascadeGO:004340940.021
myofibril assemblyGO:0030239480.021
odontogenesis of dentin containing toothGO:004247510.021
cell projection organizationGO:00300302840.021
positive regulation of cellular biosynthetic processGO:0031328680.021
positive regulation of map kinase activityGO:004340630.021
dicarboxylic acid metabolic processGO:004364810.021
cell growthGO:0016049570.021
spermatid differentiationGO:004851520.021
positive regulation of protein polymerizationGO:003227320.021
ribonucleotide biosynthetic processGO:0009260200.021
proteasomal protein catabolic processGO:001049820.021
ether metabolic processGO:001890410.021
phagocytosisGO:000690930.020
response to other organismGO:0051707970.020
regulation of gene expressionGO:00104682650.020
dna templated transcription elongationGO:000635430.020
neuron projection morphogenesisGO:00488121610.020
monoamine transportGO:001584410.020
androgen biosynthetic processGO:000670210.020
Rat
chemical homeostasisGO:0048878490.020
eye developmentGO:00016542770.020
cellular response to external stimulusGO:007149620.020
adherens junction organizationGO:003433240.020
regulation of establishment of protein localizationGO:007020140.020
camera type eye developmentGO:00430102220.019
membrane lipid biosynthetic processGO:004646720.019
cellular component assembly involved in morphogenesisGO:00109271070.019
regulation of steroid hormone secretionGO:200083110.019
macromolecule modificationGO:00434121110.019
i kappab kinase nf kappab signalingGO:000724940.019
cellular response to light stimulusGO:007148240.019
regulation of carbohydrate biosynthetic processGO:004325510.019
limbic system developmentGO:0021761160.019
muscle cell developmentGO:00550011150.019
monovalent inorganic cation transportGO:0015672420.019
regulation of epithelial cell proliferationGO:005067830.019
regulation of microtubule cytoskeleton organizationGO:007050730.019
embryonic organ developmentGO:00485683810.019
muscle contractionGO:0006936180.019
embryonic heart tube developmentGO:00350501330.019
hemopoiesisGO:00300971830.018
protein metabolic processGO:00195381830.018
cell morphogenesis involved in neuron differentiationGO:00486671630.018
mesenchymal cell differentiationGO:0048762870.018
small molecule biosynthetic processGO:0044283160.018
Rat
neuron neuron synaptic transmissionGO:000727010.018
regulation of cell activationGO:005086510.018
somitogenesisGO:0001756870.018
regulation of protein localization to nucleusGO:190018020.018
sexual reproductionGO:0019953360.017
cellular modified amino acid metabolic processGO:000657530.017
regulation of protein ubiquitinationGO:003139630.017
neuron developmentGO:00486662620.017
cellular hormone metabolic processGO:0034754190.017
positive regulation of multi organism processGO:004390230.017
phosphate containing compound metabolic processGO:00067961080.017
peptide transportGO:001583310.017
myeloid cell differentiationGO:0030099860.017
cell adhesionGO:0007155400.017
peptidyl lysine acetylationGO:001839420.017
regulation of hormone metabolic processGO:003235060.017
divalent inorganic cation transportGO:0072511210.017
lysosomal transportGO:000704120.017
regulation of synaptic plasticityGO:004816710.017
regulation of transcription from rna polymerase ii promoterGO:00063571140.017
smooth muscle contractionGO:000693920.017
forebrain developmentGO:0030900960.017
reproductionGO:0000003400.017
ameboidal type cell migrationGO:00016671430.017
intracellular receptor signaling pathwayGO:0030522300.017
response to hexoseGO:000974630.017
regenerationGO:0031099910.017
generation of neuronsGO:00486993850.016
heart developmentGO:00075073130.016
regulation of multicellular organism growthGO:004001440.016
positive regulation of purine nucleotide metabolic processGO:190054490.016
oocyte maturationGO:000155640.016
positive regulation of cytoskeleton organizationGO:005149530.016
cellular response to toxic substanceGO:009723710.016
single organism reproductive processGO:0044702400.016
nuclear migrationGO:000709730.016
stem cell proliferationGO:007208940.016
membrane fusionGO:006102520.016
positive regulation of macromolecule metabolic processGO:0010604930.016
protein acylationGO:004354330.016
positive regulation of cyclic nucleotide biosynthetic processGO:003080480.016
steroid metabolic processGO:000820270.016
axon developmentGO:00615641660.016
positive regulation of protein complex assemblyGO:003133420.016
growthGO:00400071740.016
multicellular organismal reproductive processGO:0048609350.016
regulation of oocyte developmentGO:006028130.016
regulation of programmed cell deathGO:00430671010.016
regulation of meiotic cell cycleGO:005144510.016
cytoskeleton dependent cytokinesisGO:006164030.016
positive regulation of inflammatory responseGO:005072910.016
positive regulation of lipid metabolic processGO:004583410.016
internal protein amino acid acetylationGO:000647520.016
regulation of cell cycleGO:0051726520.016
gtp metabolic processGO:004603940.016
cytokinesisGO:000091030.015
regulation of protein catabolic processGO:004217610.015
purine containing compound biosynthetic processGO:0072522200.015
cellular component assemblyGO:00226071700.015
regulation of cytokine productionGO:000181730.015
calcium ion importGO:007050940.015
mesodermal cell differentiationGO:0048333210.015
gamete generationGO:0007276330.015
positive regulation of programmed cell deathGO:0043068290.015
negative regulation of apoptotic processGO:0043066550.015
regulation of calcium mediated signalingGO:005084810.015
kidney developmentGO:0001822920.015
regulation of i kappab kinase nf kappab signalingGO:004312240.015

hsd17b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.060