Danio rerio

0 known processes

rapgef1

Rap guanine nucleotide exchange factor (GEF) 1

(Aliases: zgc:56372,MGC56372,rapgef1b,GRF2)

rapgef1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.227
brain developmentGO:00074202930.152
modification dependent protein catabolic processGO:001994130.135
cellular macromolecule biosynthetic processGO:00346452240.120
camera type eye developmentGO:00430102220.117
central nervous system developmentGO:00074173870.116
embryo development ending in birth or egg hatchingGO:00097922710.104
regulation of signalingGO:00230512350.089
cellular component movementGO:00069283350.085
retina development in camera type eyeGO:00600411460.082
cellular nitrogen compound metabolic processGO:00346412900.081
head developmentGO:00603223030.079
heterocycle metabolic processGO:00464832900.079
regulation of cell communicationGO:00106462320.071
rna metabolic processGO:00160702190.070
nuclear transportGO:005116940.070
single organism organelle organizationGO:19025891990.069
cellular macromolecule metabolic processGO:00442603910.067
nitrogen compound metabolic processGO:00068073190.066
negative regulation of biological processGO:00485193040.065
transcription dna templatedGO:00063511810.065
protein metabolic processGO:00195381830.065
gene expressionGO:00104672520.064
eye developmentGO:00016542770.060
positive regulation of map kinase activityGO:004340630.060
regulation of response to stimulusGO:00485832690.060
regulation of signal transductionGO:00099662250.059
regulation of multicellular organism growthGO:004001440.057
regulation of biosynthetic processGO:00098892500.056
sensory organ developmentGO:00074233930.055
skeletal system developmentGO:00015011810.055
tube morphogenesisGO:00352393490.055
organic substance biosynthetic processGO:19015762890.052
organelle organizationGO:00069962270.052
regulation of rna biosynthetic processGO:20011412130.051
maintenance of locationGO:005123540.051
morphogenesis of an epitheliumGO:00020093330.051
positive regulation of transportGO:005105020.049
ubiquitin dependent protein catabolic processGO:000651130.048
agingGO:000756820.048
regulation of multicellular organismal developmentGO:20000262230.046
regulation of rna metabolic processGO:00512522240.046
immune system processGO:00023762410.045
regulation of primary metabolic processGO:00800903110.045
organic cyclic compound metabolic processGO:19013603010.044
rna biosynthetic processGO:00327741810.044
negative regulation of cellular processGO:00485232830.044
digestive system developmentGO:00551232890.043
positive regulation of catabolic processGO:000989640.043
digestive tract developmentGO:00485652650.042
nucleocytoplasmic transportGO:000691340.042
regulation of transcription dna templatedGO:00063552130.042
generation of neuronsGO:00486993850.041
cell motilityGO:00488702440.039
cognitionGO:005089010.039
regulation of multicellular organismal processGO:00512392770.038
response to nutrientGO:000758430.038
nucleobase containing compound biosynthetic processGO:00346542050.037
nucleobase containing compound metabolic processGO:00061392740.037
peptidyl serine phosphorylationGO:001810510.037
modification dependent macromolecule catabolic processGO:004363230.036
cellular component biogenesisGO:00440851780.036
regionalizationGO:00030022740.036
regulation of nitrogen compound metabolic processGO:00511712510.035
positive regulation of stress activated mapk cascadeGO:003287430.035
regulation of protein kinase b signalingGO:005189680.034
positive regulation of cellular catabolic processGO:003133130.034
aromatic compound biosynthetic processGO:00194382170.034
stem cell maintenanceGO:001982740.034
digestive tract morphogenesisGO:00485462310.034
macromolecule biosynthetic processGO:00090592270.033
signal transductionGO:00071654550.033
locomotionGO:00400113130.032
proteolysis involved in cellular protein catabolic processGO:005160330.032
response to stressGO:00069502630.032
cellular protein metabolic processGO:00442671290.032
establishment of localizationGO:00512342440.032
lateral inhibitionGO:004633110.032
cellular protein modification processGO:00064641000.032
stem cell proliferationGO:007208940.032
regulation of cellular carbohydrate metabolic processGO:001067540.032
regulation of macromolecule metabolic processGO:00602553170.031
nucleic acid metabolic processGO:00903042440.031
lipid storageGO:001991510.031
microtubule based processGO:0007017600.031
taxisGO:00423301090.031
regulation of gene expressionGO:00104682650.031
stem cell divisionGO:001714510.030
cellular biosynthetic processGO:00442492860.030
regulation of developmental processGO:00507932470.030
multicellular organism growthGO:003526440.030
regulation of glucose importGO:004632410.030
cellular process involved in reproduction in multicellular organismGO:0022412280.030
regulation of cellular macromolecule biosynthetic processGO:20001122220.030
regulation of macromolecule biosynthetic processGO:00105562250.029
dorsal ventral pattern formationGO:00099531250.029
response to external stimulusGO:00096052640.029
embryonic organ morphogenesisGO:00485622740.029
cell surface receptor signaling pathwayGO:00071663250.029
organic cyclic compound biosynthetic processGO:19013622230.029
positive regulation of jnk cascadeGO:004633030.029
regulation of establishment of protein localizationGO:007020140.028
cellular component morphogenesisGO:00329893360.028
neuron projection guidanceGO:0097485860.028
cellular component assemblyGO:00226071700.028
embryonic organ developmentGO:00485683810.028
positive regulation of macromolecule metabolic processGO:0010604930.027
localization of cellGO:00516742440.027
macromolecule modificationGO:00434121110.027
immune system developmentGO:00025201910.027
regulation of cellular biosynthetic processGO:00313262450.026
mitotic cell cycleGO:0000278640.026
regulation of nucleobase containing compound metabolic processGO:00192192500.026
hemopoiesisGO:00300971830.026
hindbrain developmentGO:0030902910.026
response to chemicalGO:00422213200.026
axonogenesisGO:00074091520.026
regulation of carbohydrate metabolic processGO:000610940.025
heart developmentGO:00075073130.025
biosynthetic processGO:00090582940.025
response to abiotic stimulusGO:00096281220.025
negative regulation of protein phosphorylationGO:000193340.025
neuron developmentGO:00486662620.025
heterocycle biosynthetic processGO:00181302150.025
cellular nitrogen compound biosynthetic processGO:00442712180.024
regulation of bindingGO:005109830.024
phagocytosisGO:000690930.024
organic acid metabolic processGO:0006082310.024
positive regulation of response to stimulusGO:0048584800.024
response to carbohydrateGO:000974330.024
gastrulationGO:00073692080.024
cellular response to chemical stimulusGO:00708871570.023
oxoacid metabolic processGO:0043436310.023
cellular localizationGO:0051641970.023
positive regulation of cell cycleGO:004578730.023
positive regulation of protein kinase b signalingGO:005189710.023
negative regulation of cell communicationGO:0010648960.023
protein modification processGO:00362111000.023
regulation of synapse assemblyGO:005196330.023
positive regulation of dna metabolic processGO:005105410.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
regulation of protein targetingGO:190353320.023
gland developmentGO:00487321430.023
negative regulation of signalingGO:0023057960.022
adherens junction organizationGO:003433240.022
negative regulation of response to stimulusGO:00485851040.022
spindle localizationGO:0051653120.022
retina morphogenesis in camera type eyeGO:0060042790.022
positive regulation of metabolic processGO:00098931080.022
negative regulation of signal transductionGO:0009968940.022
cellular protein catabolic processGO:004425740.021
single organism localizationGO:19025782250.021
heart morphogenesisGO:00030071560.021
cellular response to external stimulusGO:007149620.021
cell cycleGO:0007049930.021
embryonic hemopoiesisGO:0035162530.021
gamete generationGO:0007276330.021
regulation of molecular functionGO:0065009700.021
regulation of synapse organizationGO:005080730.021
anterior posterior pattern specificationGO:00099521520.020
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.020
regulation of stem cell differentiationGO:200073640.020
endodermal cell fate specificationGO:0001714170.020
regulation of cytokine productionGO:000181730.020
guanosine containing compound metabolic processGO:190106840.020
establishment of spindle orientationGO:0051294100.020
regulation of extrinsic apoptotic signaling pathwayGO:200123630.020
protein phosphorylationGO:0006468470.020
nuclear importGO:005117030.020
small molecule metabolic processGO:0044281770.020
diencephalon developmentGO:0021536580.019
neuroblast proliferationGO:000740520.019
regulation of cell activationGO:005086510.019
determination of bilateral symmetryGO:00098552040.019
regulation of dna replicationGO:000627530.019
epidermis developmentGO:0008544480.019
regulation of meiotic cell cycleGO:005144510.019
cellular carbohydrate metabolic processGO:004426240.019
actin filament based processGO:0030029640.019
cell projection organizationGO:00300302840.019
regulation of cellular amino acid metabolic processGO:000652100.019
specification of symmetryGO:00097992040.019
transcription from rna polymerase ii promoterGO:0006366800.019
synaptic target recognitionGO:000803910.019
negative regulation of multicellular organismal processGO:0051241690.019
negative regulation of gene expressionGO:0010629650.019
cell proliferationGO:0008283800.019
chemotaxisGO:00069351040.019
cellular response to extracellular stimulusGO:003166820.019
cellular response to starvationGO:000926710.019
intracellular signal transductionGO:0035556850.019
phosphate containing compound metabolic processGO:00067961080.019
gtp catabolic processGO:000618420.019
cellular amine metabolic processGO:004410620.018
response to monosaccharideGO:003428430.018
regulation of cellular metabolic processGO:00313233200.018
regulation of protein transportGO:005122330.018
response to glucoseGO:000974930.018
extrinsic apoptotic signaling pathwayGO:009719130.018
positive regulation of glucose transportGO:001082810.018
guanosine containing compound catabolic processGO:190106920.018
cell migrationGO:00164772370.018
system processGO:00030081850.018
camera type eye morphogenesisGO:00485931080.018
regulation of purine nucleotide catabolic processGO:003312120.018
cellular response to nutrient levelsGO:003166920.017
skin developmentGO:0043588540.017
single organism metabolic processGO:00447102170.017
developmental growthGO:00485891660.017
nucleic acid templated transcriptionGO:00976591810.017
regulation of organ growthGO:004662030.017
negative regulation of metabolic processGO:0009892860.017
response to vitaminGO:003327330.017
cellular aromatic compound metabolic processGO:00067252950.017
regulation of response to cytokine stimulusGO:006075930.017
carboxylic acid metabolic processGO:0019752220.017
amine metabolic processGO:000930820.017
neuron projection developmentGO:00311751800.017
organelle localizationGO:0051640490.017
nuclear exportGO:005116810.017
positive regulation of carbohydrate metabolic processGO:004591310.017
regenerationGO:0031099910.016
negative regulation of reproductive processGO:200024230.016
cell substrate adhesionGO:003158940.016
negative regulation of response to cytokine stimulusGO:006076120.016
negative chemotaxisGO:005091910.016
protein kinase b signalingGO:004349190.016
regulation of sodium ion transportGO:000202820.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
positive regulation of cellular component biogenesisGO:004408930.015
regulation of cellular amine metabolic processGO:003323800.015
activation of mapk activityGO:000018730.015
proteasomal protein catabolic processGO:001049820.015
negative regulation of small gtpase mediated signal transductionGO:005105810.015
circadian sleep wake cycle processGO:002241020.015
cell cycle g1 s phase transitionGO:004484310.015
response to woundingGO:00096111160.015
negative regulation of nitrogen compound metabolic processGO:0051172590.015
response to hexoseGO:000974630.015
negative regulation of ras protein signal transductionGO:004658010.015
phosphorus metabolic processGO:00067931090.015
cell morphogenesisGO:00009022890.015
positive regulation of nitrogen compound metabolic processGO:0051173690.015
regulation of reproductive processGO:200024140.015
phosphorylationGO:0016310690.015
reactive nitrogen species metabolic processGO:200105700.015
cytoskeleton organizationGO:0007010960.015
negative regulation of developmental processGO:0051093650.015
macromolecular complex subunit organizationGO:0043933740.015
protein importGO:001703830.015
cell projection morphogenesisGO:00488582440.014
positive regulation of reproductive processGO:200024320.014
meiotic nuclear divisionGO:000712640.014
inner ear developmentGO:00488391260.014
axon guidanceGO:0007411860.014
blood vessel morphogenesisGO:00485142160.014
cell fate commitmentGO:0045165990.014
regulation of nucleoside metabolic processGO:000911820.014
protein localization to nucleusGO:003450430.014
response to drugGO:004249330.014
neuron differentiationGO:00301823530.014
photoreceptor cell differentiationGO:0046530550.014
myotube differentiationGO:0014902450.014
regulation of intracellular signal transductionGO:1902531570.014
g1 s transition of mitotic cell cycleGO:000008210.014
positive regulation of gtpase activityGO:004354710.014
regulation of circadian rhythmGO:004275240.014
regulation of cytoplasmic transportGO:190364940.014
protein complex subunit organizationGO:0071822460.014
regulation of nervous system developmentGO:0051960900.014
regulation of transcription from rna polymerase ii promoterGO:00063571140.014
establishment of spindle localizationGO:0051293120.014
cell matrix adhesionGO:000716040.013
renal system developmentGO:0072001940.013
somatic stem cell maintenanceGO:003501910.013
lamellipodium assemblyGO:003003210.013
positive regulation of cell activationGO:005086710.013
regulation of cell developmentGO:00602841000.013
protein targeting to nucleusGO:004474430.013
positive regulation of nucleoside metabolic processGO:004597910.013
gtp metabolic processGO:004603940.013
multi organism processGO:00517041340.013
positive regulation of multicellular organismal processGO:0051240520.013
centrosome cycleGO:000709810.013
regulation of gtp catabolic processGO:003312420.013
blood vessel developmentGO:00015682460.013
photoreceptor cell outer segment organizationGO:003584590.013
nitric oxide biosynthetic processGO:000680920.013
positive regulation of blood circulationGO:190352420.013
response to light stimulusGO:0009416460.013
determination of left right symmetryGO:00073681790.013
sex determinationGO:000753010.013
striated muscle cell developmentGO:00550021080.013
negative regulation of macromolecule metabolic processGO:0010605760.013
adult behaviorGO:003053420.013
regulation of mrna processingGO:005068430.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
mitotic cell cycle processGO:1903047480.013
regulation of glucose transportGO:001082710.013
negative regulation of nucleobase containing compound metabolic processGO:0045934590.013
negative regulation of cytokine productionGO:000181810.013
regulation of cellular protein metabolic processGO:0032268520.013
positive regulation of jun kinase activityGO:004350720.013
epithelial tube morphogenesisGO:00605621480.013
positive regulation of notch signaling pathwayGO:004574730.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
protein import into nucleusGO:000660630.012
synaptic growth at neuromuscular junctionGO:005112420.012
negative regulation of kinase activityGO:003367340.012
regulation of cell cycleGO:0051726520.012
growthGO:00400071740.012
positive regulation of secretionGO:005104710.012
circadian sleep wake cycleGO:004274520.012
cellular ketone metabolic processGO:0042180110.012
microtubule cytoskeleton organizationGO:0000226330.012
regulation of protein modification processGO:0031399290.012
negative regulation of nucleic acid templated transcriptionGO:1903507450.012
pyruvate metabolic processGO:000609010.012
response to organic substanceGO:00100331530.012
organonitrogen compound metabolic processGO:1901564740.012
single organism cellular localizationGO:1902580460.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.012
rna localizationGO:000640340.012
circadian sleep wake cycle sleepGO:005080210.012
chordate embryonic developmentGO:00430092710.012
positive regulation of purine nucleotide catabolic processGO:003312310.012
atp catabolic processGO:000620040.012
negative regulation of cellular metabolic processGO:0031324770.012
convergent extensionGO:00600261180.012
cellular amino acid metabolic processGO:000652070.012
epithelial cell differentiationGO:00308551160.012
cell agingGO:000756920.011
female sex differentiationGO:004666040.011
positive regulation of molecular functionGO:0044093330.011
muscle cell differentiationGO:00426921390.011
wound healingGO:0042060900.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
regulation of smoothened signaling pathwayGO:0008589180.011
cartilage developmentGO:0051216960.011
positive regulation of catalytic activityGO:0043085250.011
centrosome organizationGO:005129710.011
positive regulation of cellular biosynthetic processGO:0031328680.011
neurotransmitter secretionGO:000726920.011
cell morphogenesis involved in differentiationGO:00009041950.011
regulation of phosphate metabolic processGO:0019220430.011
cellular response to stressGO:0033554620.011
embryonic skeletal system morphogenesisGO:0048704930.011
striated muscle cell differentiationGO:00511461290.011
inositol lipid mediated signalingGO:004801720.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of response to nutrient levelsGO:003210710.011
stem cell developmentGO:0048864820.011
embryonic skeletal system developmentGO:0048706970.011
ear developmentGO:00435831270.011
cellular response to organic substanceGO:00713101050.011
establishment or maintenance of cell polarityGO:0007163290.011
formation of primary germ layerGO:0001704620.011
positive regulation of signal transductionGO:0009967560.011
regulation of skeletal muscle tissue developmentGO:004864140.011
regulation of cell differentiationGO:00455951420.011
developmental maturationGO:0021700340.011
pancreas developmentGO:0031016840.011
protein secretionGO:000930610.011
regulation of protein ubiquitinationGO:003139630.010
negative regulation of multi organism processGO:004390130.010
embryonic heart tube developmentGO:00350501330.010
cellular response to endogenous stimulusGO:0071495680.010
positive regulation of protein polymerizationGO:003227320.010
regulation of metal ion transportGO:001095940.010
positive regulation of cellular carbohydrate metabolic processGO:001067610.010
positive regulation of cell adhesionGO:004578510.010
protein acylationGO:004354330.010
regulation of nucleocytoplasmic transportGO:004682220.010
wnt signaling pathwayGO:0016055800.010
positive regulation of biological processGO:00485182530.010
hypothalamus cell differentiationGO:002197940.010
positive regulation of nucleotide catabolic processGO:003081310.010
deathGO:00162651210.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
establishment of mitotic spindle localizationGO:0040001120.010
cellular response to organic cyclic compoundGO:0071407380.010
negative regulation of stem cell differentiationGO:200073720.010
negative regulation of synapse assemblyGO:005196420.010
forebrain developmentGO:0030900960.010

rapgef1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.030
nervous system diseaseDOID:86300.015