Danio rerio

0 known processes

helb

helicase (DNA) B

(Aliases: sb:cb596,id:ibd5145,si:dkey-150i15.3,id:ibd3187)

helb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular protein catabolic processGO:004425740.187
regulation of multicellular organismal processGO:00512392770.156
cell projection morphogenesisGO:00488582440.101
proteolysis involved in cellular protein catabolic processGO:005160330.068
proteasomal protein catabolic processGO:001049820.066
regulation of cell communicationGO:00106462320.062
larval developmentGO:000216420.062
ubiquitin dependent protein catabolic processGO:000651130.062
rna metabolic processGO:00160702190.059
protein import into nucleusGO:000660630.059
myeloid cell differentiationGO:0030099860.058
negative regulation of biological processGO:00485193040.053
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.051
immune system processGO:00023762410.051
regulation of multicellular organism growthGO:004001440.050
modification dependent macromolecule catabolic processGO:004363230.048
signal transductionGO:00071654550.046
negative regulation of cellular processGO:00485232830.045
establishment of protein localization to organelleGO:007259440.044
protein polyubiquitinationGO:000020940.043
phagocytosisGO:000690930.042
positive regulation of apoptotic signaling pathwayGO:200123510.041
nuclear transportGO:005116940.040
regulation of cytokine productionGO:000181730.040
protein metabolic processGO:00195381830.040
cellular aromatic compound metabolic processGO:00067252950.040
regulation of response to stimulusGO:00485832690.039
hemopoiesisGO:00300971830.038
cellular protein modification processGO:00064641000.038
positive regulation of transportGO:005105020.037
nucleocytoplasmic transportGO:000691340.036
mitochondrion organizationGO:000700540.036
positive regulation of stress activated mapk cascadeGO:003287430.036
multicellular organism growthGO:003526440.036
nuclear importGO:005117030.034
regulation of signal transductionGO:00099662250.034
regulation of protein targetingGO:190353320.034
positive regulation of biological processGO:00485182530.033
regulation of cell activationGO:005086510.033
regulation of cellular metabolic processGO:00313233200.033
positive regulation of programmed cell deathGO:0043068290.032
protein targeting to nucleusGO:004474430.031
regulation of cellular biosynthetic processGO:00313262450.031
agingGO:000756820.031
positive regulation of jnk cascadeGO:004633030.030
compound eye developmentGO:004874920.030
regulation of establishment of protein localizationGO:007020140.030
hematopoietic or lymphoid organ developmentGO:00485341910.029
gene expressionGO:00104672520.029
primitive hemopoiesisGO:0060215270.029
organic cyclic compound metabolic processGO:19013603010.029
extrinsic apoptotic signaling pathwayGO:009719130.028
cellular component movementGO:00069283350.028
proteolysisGO:0006508380.028
response to biotic stimulusGO:0009607970.028
heterocycle metabolic processGO:00464832900.028
cell projection organizationGO:00300302840.028
modification dependent protein catabolic processGO:001994130.027
nucleic acid metabolic processGO:00903042440.027
macromolecule modificationGO:00434121110.026
regulation of macromolecule metabolic processGO:00602553170.025
embryonic hemopoiesisGO:0035162530.025
protein importGO:001703830.025
positive regulation of jun kinase activityGO:004350720.025
generation of neuronsGO:00486993850.025
production of molecular mediator of immune responseGO:000244020.025
protein modification processGO:00362111000.025
localization of cellGO:00516742440.025
organic substance biosynthetic processGO:19015762890.024
organelle organizationGO:00069962270.024
transcription dna templatedGO:00063511810.024
single organism organelle organizationGO:19025891990.024
symbiosis encompassing mutualism through parasitismGO:004440340.024
regulation of developmental processGO:00507932470.024
macromolecular complex subunit organizationGO:0043933740.023
cell surface receptor signaling pathwayGO:00071663250.023
regionalizationGO:00030022740.023
regulation of protein complex assemblyGO:004325430.023
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.023
regulation of cell deathGO:00109411030.022
regulation of production of molecular mediator of immune responseGO:000270010.022
neuron differentiationGO:00301823530.022
regulation of proteolysisGO:0030162240.022
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.022
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.022
regulation of erk1 and erk2 cascadeGO:007037240.021
stem cell differentiationGO:00488631170.021
regulation of protein modification by small protein conjugation or removalGO:190332030.021
protein complex subunit organizationGO:0071822460.021
protein localization to nucleusGO:003450430.021
regulation of programmed cell deathGO:00430671010.021
immune system developmentGO:00025201910.021
single organism nuclear importGO:190259330.021
digestive tract morphogenesisGO:00485462310.021
regulation of reactive oxygen species metabolic processGO:200037720.020
positive regulation of apoptotic processGO:0043065290.020
regulation of cytoplasmic transportGO:190364940.020
programmed cell deathGO:00125011190.020
neuron remodelingGO:001632210.020
positive regulation of cellular catabolic processGO:003133130.020
apoptotic processGO:00069151160.020
blood vessel morphogenesisGO:00485142160.019
cell deathGO:00082191210.019
regulation of localizationGO:00328791040.019
embryonic organ developmentGO:00485683810.019
negative regulation of protein phosphorylationGO:000193340.019
positive regulation of catabolic processGO:000989640.019
erythrocyte homeostasisGO:0034101550.019
aromatic compound biosynthetic processGO:00194382170.019
digestive system developmentGO:00551232890.019
antimicrobial humoral responseGO:001973020.019
positive regulation of multi organism processGO:004390230.018
regulation of nitrogen compound metabolic processGO:00511712510.018
autophagyGO:000691440.018
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.018
positive regulation of map kinase activityGO:004340630.018
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.018
cellular macromolecule metabolic processGO:00442603910.018
cellular amino acid metabolic processGO:000652070.018
vasculature developmentGO:00019442780.018
carboxylic acid metabolic processGO:0019752220.018
negative regulation of protein localization to nucleusGO:190018120.018
mesenchyme developmentGO:00604851270.017
regulation of cellular amine metabolic processGO:003323800.017
regulation of protein import into nucleusGO:004230620.017
regulation of gene expressionGO:00104682650.017
centrosome organizationGO:005129710.017
response to uvGO:000941130.017
regulation of stem cell proliferationGO:007209120.017
regulation of purine nucleotide catabolic processGO:003312120.017
modification of morphology or physiology of other organismGO:003582140.017
peptide metabolic processGO:000651810.017
regulation of protein catabolic processGO:004217610.017
regulation of metabolic processGO:00192223590.017
membrane invaginationGO:001032410.017
brain developmentGO:00074202930.017
amine metabolic processGO:000930820.016
multi organism cellular processGO:004476420.016
cognitionGO:005089010.016
positive regulation of cell deathGO:0010942290.016
negative regulation of intracellular transportGO:003238730.016
startle responseGO:000196440.016
regulation of protein transportGO:005122330.016
positive regulation of cytokine productionGO:000181920.016
cellular macromolecule biosynthetic processGO:00346452240.016
erythrocyte differentiationGO:0030218540.016
b cell activationGO:004211320.016
regulation of nucleocytoplasmic transportGO:004682220.016
interspecies interaction between organismsGO:004441940.016
positive regulation of cell cycleGO:004578730.016
heterocycle biosynthetic processGO:00181302150.016
regulation of metal ion transportGO:001095940.015
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.015
regulation of protein ubiquitinationGO:003139630.015
ovulation cycleGO:004269820.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
positive regulation of secretionGO:005104710.015
negative regulation of kinase activityGO:003367340.015
regulation of protein localization to nucleusGO:190018020.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.015
regulation of bindingGO:005109830.015
regulation of cellular ketone metabolic processGO:001056570.015
regulation of cellular amino acid metabolic processGO:000652100.015
regulation of cellular component movementGO:0051270550.015
erk1 and erk2 cascadeGO:007037140.015
spermatid differentiationGO:004851520.015
activation of mapk activityGO:000018730.015
muscle structure developmentGO:00610611960.015
cellular amine metabolic processGO:004410620.015
positive regulation of cell activationGO:005086710.015
central nervous system developmentGO:00074173870.015
nucleobase containing compound metabolic processGO:00061392740.015
regulation of nucleotide catabolic processGO:003081120.015
female sex differentiationGO:004666040.014
myeloid cell developmentGO:0061515320.014
regulation of nucleoside metabolic processGO:000911820.014
negative regulation of cytokine productionGO:000181810.014
deathGO:00162651210.014
oxoacid metabolic processGO:0043436310.014
stem cell maintenanceGO:001982740.014
regulation of cellular protein catabolic processGO:190336210.014
phagocytosis engulfmentGO:000691110.014
regulation of extrinsic apoptotic signaling pathwayGO:200123630.014
heart developmentGO:00075073130.014
viral processGO:001603210.014
cellular component disassemblyGO:002241110.014
positive regulation of cellular processGO:00485222010.014
negative regulation of cytoplasmic transportGO:190365020.013
cellular respirationGO:004533330.013
negative regulation of protein transportGO:005122430.013
organic cyclic compound biosynthetic processGO:19013622230.013
developmental programmed cell deathGO:001062340.013
ovulation cycle processGO:002260220.013
modification of morphology or physiology of other organism involved in symbiotic interactionGO:005181740.013
cellular protein metabolic processGO:00442671290.013
cellular nitrogen compound biosynthetic processGO:00442712180.013
homeostasis of number of cellsGO:0048872620.013
negative regulation of protein import into nucleusGO:004230820.013
negative regulation of secretionGO:005104820.013
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.013
cellular response to biotic stimulusGO:007121630.013
nitrogen compound metabolic processGO:00068073190.013
response to other organismGO:0051707970.013
positive regulation of production of molecular mediator of immune responseGO:000270210.013
regulation of signalingGO:00230512350.013
nucleobase containing compound biosynthetic processGO:00346542050.013
cell migrationGO:00164772370.013
protein acylationGO:004354330.013
response to nutrientGO:000758430.013
guanosine containing compound metabolic processGO:190106840.012
nucleic acid templated transcriptionGO:00976591810.012
actin cytoskeleton organizationGO:0030036630.012
cellular nitrogen compound metabolic processGO:00346412900.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
positive regulation of immune effector processGO:000269930.012
regulation of intracellular protein transportGO:003315730.012
single organism transportGO:00447652060.012
organic acid metabolic processGO:0006082310.012
reactive oxygen species metabolic processGO:007259360.012
regulation of protein bindingGO:004339330.012
neuron developmentGO:00486662620.012
positive regulation of secretion by cellGO:190353210.012
positive regulation of nucleoside metabolic processGO:004597910.012
regulation of gtp catabolic processGO:003312420.012
lipid storageGO:001991510.012
lymphocyte proliferationGO:004665110.012
positive regulation of protein complex assemblyGO:003133420.012
cellular carbohydrate metabolic processGO:004426240.012
neurotransmitter secretionGO:000726920.012
cellular response to chemical stimulusGO:00708871570.012
aorta developmentGO:003590440.012
cellular amide metabolic processGO:004360340.011
axonogenesisGO:00074091520.011
regulation of primary metabolic processGO:00800903110.011
regulation of reproductive processGO:200024140.011
regulation of gtpase activityGO:004308720.011
cellular response to external stimulusGO:007149620.011
regulation of apoptotic processGO:0042981980.011
mononuclear cell proliferationGO:003294310.011
regulation of rna metabolic processGO:00512522240.011
regulation of stem cell differentiationGO:200073640.011
regulation of peptidase activityGO:0052547230.011
regulation of jun kinase activityGO:004350630.011
regulation of chromosome segregationGO:005198310.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
regulation of rna biosynthetic processGO:20011412130.011
regulation of cell shapeGO:000836010.011
regulation of protein metabolic processGO:0051246560.011
establishment of localizationGO:00512342440.011
cellular response to molecule of bacterial originGO:007121930.011
fatty acid biosynthetic processGO:000663340.011
dorsal ventral pattern formationGO:00099531250.011
cell morphogenesisGO:00009022890.011
ovarian follicle developmentGO:000154120.011
cellular response to stressGO:0033554620.011
i kappab kinase nf kappab signalingGO:000724940.011
maintenance of locationGO:005123540.010
negative regulation of nuclear divisionGO:005178430.010
regulation of leukocyte mediated immunityGO:000270310.010
heart contractionGO:0060047710.010
transcription elongation from rna polymerase ii promoterGO:000636830.010
mitotic cell cycle embryonicGO:004544820.010
tube closureGO:006060610.010
hypothalamus cell differentiationGO:002197940.010
regulation of receptor mediated endocytosisGO:004825940.010
cellular component biogenesisGO:00440851780.010
positive regulation of cellular amine metabolic processGO:003324000.010
developmental maturationGO:0021700340.010
regulation of macromolecule biosynthetic processGO:00105562250.010
regulation of biosynthetic processGO:00098892500.010
protein stabilizationGO:005082120.010
dorsal aorta developmentGO:003590740.010
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.010
small molecule catabolic processGO:004428230.010
response to external biotic stimulusGO:0043207970.010

helb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.025
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.017
organ system cancerDOID:005068600.014
sensory system diseaseDOID:005015500.013
eye and adnexa diseaseDOID:149200.013
disease of metabolismDOID:001466700.012
eye diseaseDOID:561400.011