Danio rerio

0 known processes

mll2

myeloid/lymphoid or mixed-lineage leukemia 2

(Aliases: im:7157663)

mll2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h4 k20 methylationGO:003477020.470
histone lysine methylationGO:0034968120.303
protein methylationGO:0006479130.233
methylationGO:0032259220.230
histone h3 k36 methylationGO:001045220.215
chromatin modificationGO:0016568210.190
histone h3 k4 methylationGO:005156820.180
protein alkylationGO:0008213130.172
peptidyl lysine methylationGO:001802230.161
nucleic acid metabolic processGO:00903042440.158
nitrogen compound metabolic processGO:00068073190.157
regulation of metabolic processGO:00192223590.147
organic substance biosynthetic processGO:19015762890.143
nucleobase containing compound biosynthetic processGO:00346542050.141
macromolecule methylationGO:0043414190.139
peptidyl lysine dimethylationGO:001802710.125
regulation of cellular metabolic processGO:00313233200.120
heterocycle biosynthetic processGO:00181302150.116
macromolecule biosynthetic processGO:00090592270.111
histone methylationGO:0016571130.103
cellular nitrogen compound biosynthetic processGO:00442712180.100
single organism metabolic processGO:00447102170.098
aromatic compound biosynthetic processGO:00194382170.098
regulation of macromolecule metabolic processGO:00602553170.097
peptidyl lysine trimethylationGO:001802310.094
biosynthetic processGO:00090582940.094
regulation of macromolecule biosynthetic processGO:00105562250.092
organelle organizationGO:00069962270.091
heterocycle metabolic processGO:00464832900.090
rna biosynthetic processGO:00327741810.086
histone modificationGO:0016570200.086
gene expressionGO:00104672520.085
negative regulation of biological processGO:00485193040.084
nucleic acid templated transcriptionGO:00976591810.084
cellular aromatic compound metabolic processGO:00067252950.083
cellular macromolecule metabolic processGO:00442603910.082
nucleobase containing compound metabolic processGO:00061392740.082
histone h3 k9 methylationGO:005156750.080
covalent chromatin modificationGO:0016569200.077
regulation of cellular macromolecule biosynthetic processGO:20001122220.076
regulation of transcription dna templatedGO:00063552130.076
cellular biosynthetic processGO:00442492860.075
organic cyclic compound metabolic processGO:19013603010.074
regulation of nitrogen compound metabolic processGO:00511712510.074
transcription dna templatedGO:00063511810.074
regulation of primary metabolic processGO:00800903110.072
rna metabolic processGO:00160702190.066
cellular nitrogen compound metabolic processGO:00346412900.063
regulation of gene expressionGO:00104682650.063
cellular protein metabolic processGO:00442671290.062
regulation of rna biosynthetic processGO:20011412130.061
single organism organelle organizationGO:19025891990.059
organic cyclic compound biosynthetic processGO:19013622230.056
chromosome organizationGO:0051276310.056
regulation of biosynthetic processGO:00098892500.053
multicellular organism growthGO:003526440.053
regulation of nucleobase containing compound metabolic processGO:00192192500.052
macromolecule modificationGO:00434121110.051
protein modification processGO:00362111000.049
regulation of rna metabolic processGO:00512522240.049
cellular protein modification processGO:00064641000.048
protein metabolic processGO:00195381830.046
negative regulation of metabolic processGO:0009892860.042
regulation of multicellular organism growthGO:004001440.042
response to chemicalGO:00422213200.042
response to stressGO:00069502630.042
agingGO:000756820.041
chromatin organizationGO:0006325220.040
response to external stimulusGO:00096052640.040
regulation of response to stimulusGO:00485832690.038
positive regulation of transportGO:005105020.038
larval developmentGO:000216420.037
regulation of cellular biosynthetic processGO:00313262450.037
negative regulation of macromolecule metabolic processGO:0010605760.037
peptidyl serine phosphorylationGO:001810510.036
meiotic nuclear divisionGO:000712640.036
skeletal system developmentGO:00015011810.035
cellular macromolecule biosynthetic processGO:00346452240.034
regulation of nucleic acid templated transcriptionGO:19035062130.033
cellular response to external stimulusGO:007149620.033
cell projection morphogenesisGO:00488582440.033
neuron differentiationGO:00301823530.033
cell morphogenesisGO:00009022890.032
negative regulation of kinase activityGO:003367340.032
generation of neuronsGO:00486993850.032
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.031
cellular amine metabolic processGO:004410620.031
negative regulation of cellular processGO:00485232830.031
amine metabolic processGO:000930820.030
regulation of cellular amino acid metabolic processGO:000652100.030
cellular response to nutrient levelsGO:003166920.030
negative regulation of protein phosphorylationGO:000193340.030
negative regulation of gene expressionGO:0010629650.029
regulation of cellular amine metabolic processGO:003323800.029
protein acetylationGO:000647320.028
regulation of transcription from rna polymerase ii promoterGO:00063571140.028
transcription from rna polymerase ii promoterGO:0006366800.027
internal peptidyl lysine acetylationGO:001839320.027
female sex differentiationGO:004666040.027
macromolecular complex subunit organizationGO:0043933740.026
cellular response to chemical stimulusGO:00708871570.026
neuron developmentGO:00486662620.025
central nervous system developmentGO:00074173870.025
internal protein amino acid acetylationGO:000647520.025
cell projection organizationGO:00300302840.025
negative regulation of nucleobase containing compound metabolic processGO:0045934590.025
maintenance of locationGO:005123540.025
cellular ketone metabolic processGO:0042180110.024
peptidyl lysine acetylationGO:001839420.024
positive regulation of cellular amino acid metabolic processGO:004576400.024
cellular response to extracellular stimulusGO:003166820.024
cellular component morphogenesisGO:00329893360.024
peptidyl lysine monomethylationGO:001802610.024
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.024
negative regulation of biosynthetic processGO:0009890550.024
cell morphogenesis involved in neuron differentiationGO:00486671630.024
positive regulation of cellular catabolic processGO:003133130.023
positive regulation of catabolic processGO:000989640.023
cell part morphogenesisGO:00329902460.023
oxoacid metabolic processGO:0043436310.023
histone h3 k9 modificationGO:006164750.023
regulation of cellular component organizationGO:0051128860.023
signal transductionGO:00071654550.023
cellular amino acid metabolic processGO:000652070.022
negative regulation of cellular biosynthetic processGO:0031327550.022
chordate embryonic developmentGO:00430092710.022
digestive system developmentGO:00551232890.022
response to drugGO:004249330.022
negative regulation of cellular metabolic processGO:0031324770.022
female gonad developmentGO:000858540.022
regulation of dna templated transcription elongationGO:003278430.022
phagocytosisGO:000690930.022
gtp catabolic processGO:000618420.022
growthGO:00400071740.021
negative regulation of nitrogen compound metabolic processGO:0051172590.021
positive regulation of gtpase activityGO:004354710.021
regulation of developmental processGO:00507932470.021
regulation of cellular ketone metabolic processGO:001056570.021
dna templated transcription elongationGO:000635430.021
positive regulation of dna templated transcription elongationGO:003278610.021
negative regulation of nucleic acid templated transcriptionGO:1903507450.021
regulation of establishment of protein localizationGO:007020140.021
regulation of multicellular organismal processGO:00512392770.021
response to nutrientGO:000758430.021
regulation of meiotic cell cycleGO:005144510.020
positive regulation of biological processGO:00485182530.020
axonogenesisGO:00074091520.020
positive regulation of macromolecule metabolic processGO:0010604930.020
establishment of localizationGO:00512342440.020
mitochondrion organizationGO:000700540.020
head developmentGO:00603223030.020
positive regulation of cellular amine metabolic processGO:003324000.020
axon developmentGO:00615641660.020
cognitionGO:005089010.020
small molecule metabolic processGO:0044281770.019
organic acid metabolic processGO:0006082310.019
transcription elongation from rna polymerase ii promoterGO:000636830.019
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.019
stem cell maintenanceGO:001982740.019
regulation of protein transportGO:005122330.019
positive regulation of cellular component biogenesisGO:004408930.019
protein acylationGO:004354330.019
response to organic substanceGO:00100331530.019
peptidyl serine modificationGO:001820920.018
single organism nuclear importGO:190259330.018
organonitrogen compound metabolic processGO:1901564740.018
negative regulation of macromolecule biosynthetic processGO:0010558480.018
response to corticosteroidGO:003196010.018
regulation of cell activationGO:005086510.018
extrinsic apoptotic signaling pathwayGO:009719130.018
guanosine containing compound catabolic processGO:190106920.018
proteasomal protein catabolic processGO:001049820.018
regulation of nucleoside metabolic processGO:000911820.017
negative regulation of rna biosynthetic processGO:1902679450.017
regulation of signal transductionGO:00099662250.017
guanosine containing compound metabolic processGO:190106840.017
negative regulation of transcription dna templatedGO:0045892450.017
response to glucocorticoidGO:005138410.017
autophagyGO:000691440.017
neuron projection developmentGO:00311751800.017
homeostatic processGO:00425921420.017
positive regulation of nitrogen compound metabolic processGO:0051173690.017
development of primary female sexual characteristicsGO:004654540.017
lipid storageGO:001991510.017
modification dependent macromolecule catabolic processGO:004363230.017
nuclear transportGO:005116940.017
adult behaviorGO:003053420.017
proteolysis involved in cellular protein catabolic processGO:005160330.016
gtp metabolic processGO:004603940.016
cell morphogenesis involved in differentiationGO:00009041950.016
central nervous system neuron differentiationGO:0021953740.016
regulation of purine nucleotide catabolic processGO:003312120.016
stem cell divisionGO:001714510.016
ovulation cycleGO:004269820.016
hemopoiesisGO:00300971830.016
system processGO:00030081850.016
gastrulationGO:00073692080.016
cellular protein catabolic processGO:004425740.016
multi organism processGO:00517041340.015
regulation of signalingGO:00230512350.015
cell migrationGO:00164772370.015
establishment of protein localization to organelleGO:007259440.015
regulation of circadian rhythmGO:004275240.015
immune system processGO:00023762410.015
protein import into nucleusGO:000660630.015
regulation of cell communicationGO:00106462320.015
developmental growthGO:00485891660.015
organelle fusionGO:004828430.015
endosomal transportGO:001619720.015
ubiquitin dependent protein catabolic processGO:000651130.015
nucleocytoplasmic transportGO:000691340.015
cellular response to organic substanceGO:00713101050.015
regulation of nucleotide catabolic processGO:003081120.015
positive regulation of cellular processGO:00485222010.015
modification dependent protein catabolic processGO:001994130.015
nuclear importGO:005117030.015
regulation of cytoplasmic transportGO:190364940.015
cellular response to starvationGO:000926710.015
regulation of metal ion transportGO:001095940.015
regulation of anatomical structure morphogenesisGO:00226031300.014
positive regulation of nucleoside metabolic processGO:004597910.014
mitotic cell cycle embryonicGO:004544820.014
regulation of gtp catabolic processGO:003312420.014
regulation of protein complex assemblyGO:004325430.014
cellular component biogenesisGO:00440851780.014
cell motilityGO:00488702440.014
single organism membrane fusionGO:004480120.014
cell cycle g1 s phase transitionGO:004484310.014
positive regulation of dna metabolic processGO:005105410.014
protein importGO:001703830.014
atp catabolic processGO:000620040.014
positive regulation of cell cycleGO:004578730.014
ribonucleoside monophosphate catabolic processGO:000915840.014
positive regulation of purine nucleotide catabolic processGO:003312310.014
cellular response to oxygen levelsGO:007145310.014
cellular component movementGO:00069283350.014
regulation of synapse assemblyGO:005196330.014
positive regulation of gtp catabolic processGO:003312610.014
locomotionGO:00400113130.014
exocytosisGO:000688710.014
meiotic cell cycle processGO:190304630.014
embryo development ending in birth or egg hatchingGO:00097922710.014
purine ribonucleoside monophosphate catabolic processGO:000916940.013
regulation of cell developmentGO:00602841000.013
regulation of cytokine productionGO:000181730.013
positive regulation of cell activationGO:005086710.013
golgi vesicle transportGO:004819330.013
positive regulation of nucleotide catabolic processGO:003081310.013
fertilizationGO:000956630.013
neuron projection morphogenesisGO:00488121610.013
mesenchyme developmentGO:00604851270.013
synaptic growth at neuromuscular junctionGO:005112420.013
germ line stem cell maintenanceGO:003071820.013
cytokinesisGO:000091030.013
heart developmentGO:00075073130.013
dna alkylationGO:000630580.013
cell surface receptor signaling pathwayGO:00071663250.013
carboxylic acid metabolic processGO:0019752220.013
nucleoside monophosphate catabolic processGO:000912540.013
regulation of protein catabolic processGO:004217610.013
regulation of synapse organizationGO:005080730.013
positive regulation of secretionGO:005104710.013
muscle organ developmentGO:00075171010.013
cellular component assembly involved in morphogenesisGO:00109271070.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.013
neuron projection guidanceGO:0097485860.013
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.013
tube morphogenesisGO:00352393490.013
g1 s transition of mitotic cell cycleGO:000008210.013
ovulation cycle processGO:002260220.013
regulation of intracellular protein transportGO:003315730.012
regulation of reproductive processGO:200024140.012
sensory organ developmentGO:00074233930.012
production of molecular mediator of immune responseGO:000244020.012
brain developmentGO:00074202930.012
membrane fusionGO:006102520.012
regulation of transporter activityGO:003240920.012
chemotaxisGO:00069351040.012
compound eye developmentGO:004874920.012
eye developmentGO:00016542770.012
regulation of histone methylationGO:003106030.012
protein localization to plasma membraneGO:007265910.012
negative regulation of mapk cascadeGO:004340940.012
protein localization to nucleusGO:003450430.012
protein targeting to nucleusGO:004474430.012
positive regulation of transcription dna templatedGO:0045893570.012
regulation of bindingGO:005109830.012
negative regulation of protein kinase activityGO:000646940.012
positive regulation of immune effector processGO:000269930.012
homeostasis of number of cellsGO:0048872620.012
striated muscle tissue developmentGO:00147061100.012
muscle structure developmentGO:00610611960.012
positive regulation of cytoskeleton organizationGO:005149530.012
rna localizationGO:000640340.012
b cell activationGO:004211320.012
negative regulation of rna metabolic processGO:0051253480.012
positive regulation of apoptotic signaling pathwayGO:200123510.012
regulation of organelle assemblyGO:190211540.012
positive regulation of cytosolic calcium ion concentrationGO:000720440.012
cellular response to decreased oxygen levelsGO:003629410.012
regulation of mrna processingGO:005068430.012
ovarian follicle developmentGO:000154120.011
stem cell proliferationGO:007208940.011
cell substrate adhesionGO:003158940.011
interspecies interaction between organismsGO:004441940.011
symbiosis encompassing mutualism through parasitismGO:004440340.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
regulation of cellular protein metabolic processGO:0032268520.011
eye morphogenesisGO:00485921440.011
regulation of gtpase activityGO:004308720.011
protein secretionGO:000930610.011
gene silencingGO:001645840.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
negative regulation of nuclear divisionGO:005178430.011
tissue remodelingGO:004877140.011
cellular carbohydrate metabolic processGO:004426240.011
cellular response to hypoxiaGO:007145610.011
regulation of calcium ion transportGO:005192420.011
cartilage developmentGO:0051216960.011
muscle cell differentiationGO:00426921390.011
striated muscle cell developmentGO:00550021080.011
viral processGO:001603210.011
positive regulation of gene expressionGO:0010628710.011
tube closureGO:006060610.011
embryonic skeletal system developmentGO:0048706970.011
regulation of nucleocytoplasmic transportGO:004682220.010
membrane invaginationGO:001032410.010
positive regulation of secretion by cellGO:190353210.010
response to endogenous stimulusGO:0009719830.010
regulation of dendrite developmentGO:005077330.010
phagocytosis engulfmentGO:000691110.010
immune system developmentGO:00025201910.010
heart contractionGO:0060047710.010
regulation of protein ubiquitinationGO:003139630.010
response to monosaccharideGO:003428430.010
response to hydrogen peroxideGO:004254230.010
positive regulation of leukocyte mediated immunityGO:000270510.010
leukocyte proliferationGO:007066110.010
cellular response to radiationGO:007147840.010
dorsal ventral pattern formationGO:00099531250.010
sequestering of calcium ionGO:005120830.010
phosphorus metabolic processGO:00067931090.010
hematopoietic or lymphoid organ developmentGO:00485341910.010
synaptic vesicle localizationGO:009747910.010
regulation of gene silencingGO:006096810.010
cellular component assemblyGO:00226071700.010
response to carbohydrateGO:000974330.010
cellular response to reactive oxygen speciesGO:003461420.010
response to external biotic stimulusGO:0043207970.010
neurotransmitter transportGO:000683620.010

mll2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.016
organ system cancerDOID:005068600.016
nervous system diseaseDOID:86300.013
musculoskeletal system diseaseDOID:1700.012
disease of metabolismDOID:001466700.012