Danio rerio

0 known processes

mll5

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

(Aliases: wu:fc74b02,zgc:64223)

mll5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.066
cellular nitrogen compound biosynthetic processGO:00442712180.058
Human
regulation of nitrogen compound metabolic processGO:00511712510.053
Human
signal transductionGO:00071654550.053
Human
regulation of cellular biosynthetic processGO:00313262450.052
Human
nuclear transportGO:005116940.051
nitrogen compound metabolic processGO:00068073190.049
Human Mouse
nucleic acid metabolic processGO:00903042440.048
Human Mouse
agingGO:000756820.046
cellular biosynthetic processGO:00442492860.045
Human
regulation of biosynthetic processGO:00098892500.044
Human
regulation of macromolecule metabolic processGO:00602553170.044
Human Mouse
cellular macromolecule metabolic processGO:00442603910.043
Human Mouse
transcription dna templatedGO:00063511810.043
Human
cellular response to molecule of bacterial originGO:007121930.042
regulation of rna metabolic processGO:00512522240.041
Human
positive regulation of transportGO:005105020.041
organic cyclic compound biosynthetic processGO:19013622230.040
Human
regulation of primary metabolic processGO:00800903110.040
Human
regulation of multicellular organismal processGO:00512392770.040
Human
nucleobase containing compound biosynthetic processGO:00346542050.039
Human
cellular protein catabolic processGO:004425740.039
nucleocytoplasmic transportGO:000691340.039
organic substance biosynthetic processGO:19015762890.039
Human
biosynthetic processGO:00090582940.037
Human
organic cyclic compound metabolic processGO:19013603010.037
Human Mouse
heterocycle biosynthetic processGO:00181302150.037
Human
stem cell maintenanceGO:001982740.037
nucleobase containing compound metabolic processGO:00061392740.037
Human Mouse
positive regulation of biological processGO:00485182530.036
Human
nuclear importGO:005117030.035
gene expressionGO:00104672520.035
Human Mouse
modification dependent protein catabolic processGO:001994130.034
multicellular organism growthGO:003526440.034
nucleic acid templated transcriptionGO:00976591810.034
Human
negative regulation of biological processGO:00485193040.033
regulation of signal transductionGO:00099662250.033
cellular nitrogen compound metabolic processGO:00346412900.032
Human Mouse
single organism metabolic processGO:00447102170.032
Human
response to chemicalGO:00422213200.032
Human
regulation of cellular metabolic processGO:00313233200.032
Human
regulation of nucleobase containing compound metabolic processGO:00192192500.032
Human
cellular aromatic compound metabolic processGO:00067252950.032
Human Mouse
cellular macromolecule biosynthetic processGO:00346452240.032
Human
establishment of protein localization to organelleGO:007259440.032
phagocytosisGO:000690930.032
hemopoiesisGO:00300971830.032
Human Mouse
rna metabolic processGO:00160702190.031
Human
regulation of transcription dna templatedGO:00063552130.031
Human
proteolysis involved in cellular protein catabolic processGO:005160330.031
single organism nuclear importGO:190259330.031
mitochondrion organizationGO:000700540.030
protein importGO:001703830.030
regulation of metabolic processGO:00192223590.030
Human Mouse
meiotic nuclear divisionGO:000712640.030
regulation of gene expressionGO:00104682650.029
Human Mouse
regulation of cell communicationGO:00106462320.029
heterocycle metabolic processGO:00464832900.029
Human Mouse
endosomal transportGO:001619720.029
regulation of cytokine productionGO:000181730.029
negative regulation of cellular processGO:00485232830.029
immune system processGO:00023762410.029
Human Mouse
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.028
regulation of multicellular organismal developmentGO:20000262230.028
Human
regulation of bindingGO:005109830.028
modification dependent macromolecule catabolic processGO:004363230.028
regulation of macromolecule biosynthetic processGO:00105562250.028
Human
regulation of mrna processingGO:005068430.028
regulation of establishment of protein localizationGO:007020140.028
regulation of cytoplasmic transportGO:190364940.028
positive regulation of cellular catabolic processGO:003133130.028
regulation of protein catabolic processGO:004217610.028
regulation of multicellular organism growthGO:004001440.027
guanosine containing compound metabolic processGO:190106840.027
sensory organ developmentGO:00074233930.027
cellular response to lipopolysaccharideGO:007122230.027
regulation of developmental processGO:00507932470.027
Human
positive regulation of catabolic processGO:000989640.027
protein acetylationGO:000647320.026
cellular response to biotic stimulusGO:007121630.026
aromatic compound biosynthetic processGO:00194382170.026
Human
cell surface receptor signaling pathwayGO:00071663250.026
proteasomal protein catabolic processGO:001049820.026
protein import into nucleusGO:000660630.026
internal protein amino acid acetylationGO:000647520.026
macromolecule biosynthetic processGO:00090592270.026
Human
organelle organizationGO:00069962270.025
Human
regulation of protein transportGO:005122330.025
immune system developmentGO:00025201910.025
Human Mouse
gtp metabolic processGO:004603940.025
ubiquitin dependent protein catabolic processGO:000651130.025
regulation of nucleic acid templated transcriptionGO:19035062130.024
Human
lipid storageGO:001991510.024
positive regulation of cellular component biogenesisGO:004408930.024
maintenance of locationGO:005123540.023
regulation of intracellular protein transportGO:003315730.023
peptidyl lysine acetylationGO:001839420.023
response to external stimulusGO:00096052640.023
rna biosynthetic processGO:00327741810.023
Human
generation of neuronsGO:00486993850.023
chordate embryonic developmentGO:00430092710.023
single organism organelle organizationGO:19025891990.023
Human
positive regulation of nitrogen compound metabolic processGO:0051173690.023
Human
regulation of signalingGO:00230512350.023
internal peptidyl lysine acetylationGO:001839320.023
positive regulation of cytokine productionGO:000181920.023
positive regulation of cell cycleGO:004578730.022
response to stressGO:00069502630.022
regulation of nucleocytoplasmic transportGO:004682220.022
stem cell proliferationGO:007208940.022
protein metabolic processGO:00195381830.022
Human
myeloid cell differentiationGO:0030099860.022
Human Mouse
system processGO:00030081850.022
protein localization to nucleusGO:003450430.022
cellular component disassemblyGO:002241110.022
cellular component morphogenesisGO:00329893360.022
single organism membrane fusionGO:004480120.022
guanosine containing compound catabolic processGO:190106920.022
response to drugGO:004249330.022
locomotionGO:00400113130.022
stem cell divisionGO:001714510.022
regulation of rna biosynthetic processGO:20011412130.021
Human
embryo development ending in birth or egg hatchingGO:00097922710.021
establishment of localizationGO:00512342440.021
cellular component movementGO:00069283350.021
regulation of response to stimulusGO:00485832690.021
centrosome organizationGO:005129710.021
regulation of cell activationGO:005086510.021
regulation of cellular macromolecule biosynthetic processGO:20001122220.021
Human
central nervous system developmentGO:00074173870.021
cell projection organizationGO:00300302840.021
regulation of nucleotide catabolic processGO:003081120.021
brain developmentGO:00074202930.020
cellular response to external stimulusGO:007149620.020
cellular amine metabolic processGO:004410620.020
extrinsic apoptotic signaling pathwayGO:009719130.020
hematopoietic or lymphoid organ developmentGO:00485341910.020
Human Mouse
cell part morphogenesisGO:00329902460.020
response to uvGO:000941130.020
cellular protein metabolic processGO:00442671290.020
Human
gtp catabolic processGO:000618420.019
regulation of cell differentiationGO:00455951420.019
Human
response to carbohydrateGO:000974330.019
vasculature developmentGO:00019442780.019
regulation of cellular ketone metabolic processGO:001056570.019
embryonic organ morphogenesisGO:00485622740.019
regulation of nucleoside metabolic processGO:000911820.019
g1 s transition of mitotic cell cycleGO:000008210.019
response to monosaccharideGO:003428430.019
single organism transportGO:00447652060.019
protein acylationGO:004354330.019
regulation of cellular amine metabolic processGO:003323800.019
regulation of protein complex assemblyGO:004325430.018
regulation of stem cell proliferationGO:007209120.018
amine metabolic processGO:000930820.018
negative regulation of catabolic processGO:000989530.018
regulation of cellular amino acid metabolic processGO:000652100.018
cellular response to extracellular stimulusGO:003166820.018
positive regulation of gtp catabolic processGO:003312610.018
positive regulation of gene expressionGO:0010628710.018
Human
response to hexoseGO:000974630.018
protein targeting to nucleusGO:004474430.018
membrane fusionGO:006102520.018
neuron differentiationGO:00301823530.018
regulation of alternative mrna splicing via spliceosomeGO:000038110.018
organonitrogen compound metabolic processGO:1901564740.018
regulation of purine nucleotide catabolic processGO:003312120.018
regulation of epithelial cell proliferationGO:005067830.017
positive regulation of secretionGO:005104710.017
heart developmentGO:00075073130.017
negative regulation of nitrogen compound metabolic processGO:0051172590.017
autophagyGO:000691440.017
carboxylic acid metabolic processGO:0019752220.017
nuclear exportGO:005116810.017
spermatid developmentGO:000728620.017
regulation of cell shapeGO:000836010.017
transportGO:00068102200.017
mitotic dna integrity checkpointGO:004477440.017
regulation of synaptic plasticityGO:004816710.017
regulation of biological qualityGO:00650082630.017
Mouse
positive regulation of cell adhesionGO:004578510.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
positive regulation of purine nucleotide catabolic processGO:003312310.017
cell cycle g1 s phase transitionGO:004484310.017
cell morphogenesisGO:00009022890.017
regulation of gtp catabolic processGO:003312420.017
spermatid differentiationGO:004851520.017
alternative mrna splicing via spliceosomeGO:000038010.017
regulation of protein ubiquitinationGO:003139630.017
cell migrationGO:00164772370.017
positive regulation of stress activated mapk cascadeGO:003287430.016
embryonic organ developmentGO:00485683810.016
cytokinesisGO:000091030.016
microtubule organizing center organizationGO:003102310.016
transcription from rna polymerase ii promoterGO:0006366800.016
cellular ketone metabolic processGO:0042180110.016
positive regulation of gtpase activityGO:004354710.016
positive regulation of cellular processGO:00485222010.016
Human
head developmentGO:00603223030.016
mitotic dna damage checkpointGO:004477340.016
protein stabilizationGO:005082120.016
cellular response to nutrient levelsGO:003166920.016
positive regulation of nucleotide catabolic processGO:003081310.016
negative regulation of metabolic processGO:0009892860.016
regulation of synapse assemblyGO:005196330.016
regulation of mrna splicing via spliceosomeGO:004802430.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
cell projection morphogenesisGO:00488582440.016
cellular respirationGO:004533330.016
protein localization to plasma membraneGO:007265910.016
organic acid metabolic processGO:0006082310.016
erk1 and erk2 cascadeGO:007037140.016
ameboidal type cell migrationGO:00016671430.015
regulation of meiotic cell cycleGO:005144510.015
phagocytosis engulfmentGO:000691110.015
compound eye developmentGO:004874920.015
cell matrix adhesionGO:000716040.015
small gtpase mediated signal transductionGO:000726480.015
positive regulation of nucleoside metabolic processGO:004597910.015
negative regulation of protein phosphorylationGO:000193340.015
cell substrate adhesionGO:003158940.015
somatic muscle developmentGO:000752540.015
positive regulation of secretion by cellGO:190353210.015
digestive system developmentGO:00551232890.015
morphogenesis of an epitheliumGO:00020093330.015
protein modification processGO:00362111000.015
Human
development of primary female sexual characteristicsGO:004654540.015
negative regulation of gene expressionGO:0010629650.015
regulation of protein modification by small protein conjugation or removalGO:190332030.015
neuron developmentGO:00486662620.015
negative regulation of macromolecule metabolic processGO:0010605760.015
somatic stem cell maintenanceGO:003501910.015
single organism localizationGO:19025782250.015
oxoacid metabolic processGO:0043436310.015
protein secretionGO:000930610.015
homeostatic processGO:00425921420.015
Mouse
response to alkaloidGO:004327920.014
regulation of stem cell differentiationGO:200073640.014
cellular component assemblyGO:00226071700.014
small molecule metabolic processGO:0044281770.014
negative regulation of kinase activityGO:003367340.014
regulation of neural precursor cell proliferationGO:200017730.014
blood vessel morphogenesisGO:00485142160.014
positive regulation of cellular amine metabolic processGO:003324000.014
regulation of protein targetingGO:190353320.014
cellular response to radiationGO:007147840.014
rna localizationGO:000640340.014
meiotic cell cycle processGO:190304630.014
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.014
b cell differentiationGO:003018310.014
localization of cellGO:00516742440.014
digestive tract morphogenesisGO:00485462310.014
regulation of cell developmentGO:00602841000.014
regionalizationGO:00030022740.014
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.014
macromolecule modificationGO:00434121110.014
Human Mouse
production of molecular mediator of immune responseGO:000244020.014
regulation of protein import into nucleusGO:004230620.014
regulation of circadian rhythmGO:004275240.014
regulation of erk1 and erk2 cascadeGO:007037240.014
regulation of production of molecular mediator of immune responseGO:000270010.014
deathGO:00162651210.014
muscle structure developmentGO:00610611960.014
regulation of synapse organizationGO:005080730.014
regulation of cellular protein catabolic processGO:190336210.014
peptide transportGO:001583310.013
positive regulation of immune effector processGO:000269930.013
cellular component biogenesisGO:00440851780.013
cellular amino acid metabolic processGO:000652070.013
positive regulation of map kinase activityGO:004340630.013
tube morphogenesisGO:00352393490.013
negative regulation of cellular biosynthetic processGO:0031327550.013
germ line stem cell maintenanceGO:003071820.013
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.013
female sex differentiationGO:004666040.013
regulation of protein bindingGO:004339330.013
synaptic growth at neuromuscular junctionGO:005112420.013
organelle fusionGO:004828430.013
negative regulation of developmental processGO:0051093650.013
regulation of reproductive processGO:200024140.013
cognitionGO:005089010.013
cellular response to starvationGO:000926710.013
response to glucoseGO:000974930.013
lateral inhibitionGO:004633110.013
stem cell differentiationGO:00488631170.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
intracellular signal transductionGO:0035556850.013
cell motilityGO:00488702440.013
startle responseGO:000196440.013
response to nutrientGO:000758430.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
Human
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
determination of bilateral symmetryGO:00098552040.013
response to topologically incorrect proteinGO:003596620.013
regulation of inflammatory responseGO:005072720.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
gastrulationGO:00073692080.013
blood vessel developmentGO:00015682460.012
positive regulation of translationGO:004572710.012
glucose homeostasisGO:004259310.012
positive regulation of small gtpase mediated signal transductionGO:005105710.012
regulation of gtpase activityGO:004308720.012
stem cell developmentGO:0048864820.012
negative regulation of cellular metabolic processGO:0031324770.012
ras protein signal transductionGO:000726570.012
membrane invaginationGO:001032410.012
positive regulation of cytoskeleton organizationGO:005149530.012
protein complex disassemblyGO:004324110.012
neuroblast proliferationGO:000740520.012
negative regulation of chromosome organizationGO:200125110.012
secondary metabolic processGO:001974830.012
response to hydrogen peroxideGO:004254230.012
tissue remodelingGO:004877140.012
anterior posterior pattern specificationGO:00099521520.012
growthGO:00400071740.012
ribonucleoside monophosphate catabolic processGO:000915840.012
circulatory system processGO:0003013870.012
actin polymerization or depolymerizationGO:000815420.012
response to external biotic stimulusGO:0043207970.012
developmental programmed cell deathGO:001062340.012
atp catabolic processGO:000620040.012
b cell activationGO:004211320.012
positive regulation of cell activationGO:005086710.012
macromolecular complex disassemblyGO:003298410.012
regulation of metal ion transportGO:001095940.012
protein dephosphorylationGO:000647030.012
positive regulation of ras protein signal transductionGO:004657910.012
adherens junction organizationGO:003433240.012
negative regulation of nucleobase containing compound metabolic processGO:0045934590.012
blood circulationGO:0008015870.012
apoptotic processGO:00069151160.012
carbohydrate homeostasisGO:003350010.012
angiogenesisGO:00015251580.012
post embryonic organ developmentGO:004856940.012
regulation of protein localization to nucleusGO:190018020.012
peptidyl serine phosphorylationGO:001810510.012
locomotor rhythmGO:004547530.012
embryonic hemopoiesisGO:0035162530.012
regulation of response to biotic stimulusGO:000283120.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
tube closureGO:006060610.011
cell morphogenesis involved in differentiationGO:00009041950.011
cytoskeleton dependent cytokinesisGO:006164030.011
signal transduction in absence of ligandGO:003803410.011
negative regulation of response to stimulusGO:00485851040.011
exocytosisGO:000688710.011
cellular carbohydrate metabolic processGO:004426240.011
multi organism processGO:00517041340.011
lymphocyte proliferationGO:004665110.011
cellular response to organic substanceGO:00713101050.011
Human
developmental growthGO:00485891660.011
eye developmentGO:00016542770.011
positive regulation of epithelial cell proliferationGO:005067910.011
cellular response to reactive oxygen speciesGO:003461420.011
mesenchyme developmentGO:00604851270.011
response to abiotic stimulusGO:00096281220.011
inositol lipid mediated signalingGO:004801720.011
regulation of peptidyl tyrosine phosphorylationGO:005073010.011
mononuclear cell proliferationGO:003294310.011
negative regulation of dna metabolic processGO:005105340.011
cell agingGO:000756920.011
chemosensory behaviorGO:000763510.011
regulation of apoptotic processGO:0042981980.011
cellular protein modification processGO:00064641000.011
Human
positive regulation of dna metabolic processGO:005105410.011
regulation of dna templated transcription elongationGO:003278430.011
protein polymerizationGO:005125840.011
centrosome cycleGO:000709810.011
negative regulation of cellular catabolic processGO:003133030.011
double strand break repairGO:000630230.011
positive regulation of cellular biosynthetic processGO:0031328680.011
Human
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.011
neuron projection morphogenesisGO:00488121610.011
transcription elongation from rna polymerase ii promoterGO:000636830.011
actin filament polymerizationGO:003004120.011
myeloid cell homeostasisGO:0002262560.011
Mouse
nucleoside monophosphate catabolic processGO:000912540.011
positive regulation of erk1 and erk2 cascadeGO:007037420.011
specification of symmetryGO:00097992040.011
regulation of reactive oxygen species metabolic processGO:200037720.011
dna templated transcription elongationGO:000635430.011
positive regulation of myeloid cell differentiationGO:004563920.011
Human
positive regulation of cellular metabolic processGO:0031325940.011
Human
cell deathGO:00082191210.011
protein polyubiquitinationGO:000020940.011
negative regulation of cell communicationGO:0010648960.011
proepicardium developmentGO:000334240.011
protein targeting to membraneGO:000661210.010
negative regulation of protein kinase activityGO:000646940.010
skeletal system developmentGO:00015011810.010
regulation of cell deathGO:00109411030.010
negative regulation of translationGO:001714810.010
positive regulation of metabolic processGO:00098931080.010
Human
regulation of cell substrate adhesionGO:001081010.010
positive regulation of signal transductionGO:0009967560.010
i kappab kinase nf kappab signalingGO:000724940.010
actin mediated cell contractionGO:007025210.010
primary neural tube formationGO:001402010.010
peptidyl serine modificationGO:001820920.010
response to other organismGO:0051707970.010
cell substrate junction assemblyGO:000704420.010
programmed cell deathGO:00125011190.010
regulation of organelle assemblyGO:190211540.010
muscle cell differentiationGO:00426921390.010
regulation of jak stat cascadeGO:004642530.010
negative regulation of multi organism processGO:004390130.010
sensory organ morphogenesisGO:00905962000.010
lamellipodium organizationGO:009758110.010
negative regulation of cell differentiationGO:0045596460.010

mll5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.039
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.015
disease of metabolismDOID:001466700.014
musculoskeletal system diseaseDOID:1700.014
cancerDOID:16200.014
organ system cancerDOID:005068600.014
eye and adnexa diseaseDOID:149200.013
sensory system diseaseDOID:005015500.013
eye diseaseDOID:561400.010