Danio rerio

0 known processes

matn4

matrilin 4

(Aliases: im:7137546,matrilin-4)

matn4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cartilage developmentGO:0051216960.684
Zebrafish
skeletal system developmentGO:00015011810.533
Zebrafish
regulation of extrinsic apoptotic signaling pathwayGO:200123630.462
negative regulation of cellular processGO:00485232830.392
connective tissue developmentGO:0061448990.386
Zebrafish
blood vessel developmentGO:00015682460.366
collagen fibril organizationGO:003019910.360
response to chemicalGO:00422213200.311
regulation of signalingGO:00230512350.310
response to stressGO:00069502630.286
Mouse
embryonic organ morphogenesisGO:00485622740.241
embryonic organ developmentGO:00485683810.238
vasculature developmentGO:00019442780.236
multicellular organismal metabolic processGO:004423620.232
ameboidal type cell migrationGO:00016671430.214
regulation of developmental processGO:00507932470.198
regulation of multicellular organismal developmentGO:20000262230.192
outflow tract morphogenesisGO:000315110.184
regulation of epithelial cell proliferationGO:005067830.183
collagen metabolic processGO:003296320.179
regulation of cytokine productionGO:000181730.171
cell migrationGO:00164772370.154
regulation of cell differentiationGO:00455951420.154
response to amino acidGO:004320020.148
cell substrate adhesionGO:003158940.144
cell proliferationGO:0008283800.139
chordate embryonic developmentGO:00430092710.132
cell surface receptor signaling pathwayGO:00071663250.131
morphogenesis of an epitheliumGO:00020093330.128
positive regulation of cytokine productionGO:000181920.127
skeletal system morphogenesisGO:00487051020.123
negative regulation of epithelial cell proliferationGO:005068010.121
organic substance biosynthetic processGO:19015762890.116
response to drugGO:004249330.116
appendage morphogenesisGO:0035107560.115
multicellular organismal macromolecule metabolic processGO:004425920.114
ossificationGO:0001503230.113
cellular macromolecule metabolic processGO:00442603910.112
angiogenesisGO:00015251580.112
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.110
regulation of cell communicationGO:00106462320.107
basement membrane assemblyGO:007083130.101
regulation of cell proliferationGO:0042127370.100
regulation of cell substrate adhesionGO:001081010.097
cellular response to growth factor stimulusGO:0071363390.096
negative regulation of biological processGO:00485193040.096
negative regulation of metabolic processGO:0009892860.090
gene expressionGO:00104672520.090
response to woundingGO:00096111160.088
Mouse
positive regulation of cell adhesionGO:004578510.087
regulation of chondrocyte differentiationGO:003233010.086
muscle fiber developmentGO:0048747520.084
zymogen activationGO:003163830.082
cellular response to chemical stimulusGO:00708871570.082
biosynthetic processGO:00090582940.081
extracellular matrix organizationGO:0030198270.079
blood vessel morphogenesisGO:00485142160.079
negative regulation of protein phosphorylationGO:000193340.078
sprouting angiogenesisGO:0002040530.076
muscle structure developmentGO:00610611960.075
appendage developmentGO:0048736800.074
agingGO:000756820.071
response to nutrientGO:000758430.071
phagocytosisGO:000690930.070
cellular nitrogen compound biosynthetic processGO:00442712180.069
regulation of metabolic processGO:00192223590.069
cell morphogenesis involved in differentiationGO:00009041950.069
positive regulation of immune effector processGO:000269930.068
signal transductionGO:00071654550.068
heart morphogenesisGO:00030071560.067
extrinsic apoptotic signaling pathwayGO:009719130.067
eye morphogenesisGO:00485921440.066
protein metabolic processGO:00195381830.065
direct ossificationGO:003607230.064
cell matrix adhesionGO:000716040.064
positive regulation of cellular metabolic processGO:0031325940.063
embryo development ending in birth or egg hatchingGO:00097922710.063
regulation of response to stimulusGO:00485832690.062
collagen biosynthetic processGO:003296420.061
positive regulation of cell communicationGO:0010647560.061
regulation of cellular ketone metabolic processGO:001056570.061
negative regulation of catalytic activityGO:0043086210.060
embryonic skeletal system developmentGO:0048706970.060
positive regulation of cell differentiationGO:0045597300.058
mesenchymal cell developmentGO:0014031780.058
digestive system developmentGO:00551232890.057
multicellular organism growthGO:003526440.056
transcription from rna polymerase ii promoterGO:0006366800.056
cellular response to organic substanceGO:00713101050.056
negative regulation of multicellular organismal processGO:0051241690.056
regulation of multicellular organismal processGO:00512392770.054
regulation of cellular biosynthetic processGO:00313262450.054
mesenchymal cell differentiationGO:0048762870.053
localization of cellGO:00516742440.052
response to monosaccharideGO:003428430.052
trabecula formationGO:006034320.051
response to carbohydrateGO:000974330.051
negative regulation of signal transductionGO:0009968940.051
sensory organ developmentGO:00074233930.051
regenerationGO:0031099910.050
positive regulation of map kinase activityGO:004340630.050
retinal rod cell developmentGO:004654840.049
extracellular structure organizationGO:0043062270.049
cellular response to external stimulusGO:007149620.048
glycosaminoglycan metabolic processGO:003020390.048
regulation of primary metabolic processGO:00800903110.048
regulation of cell deathGO:00109411030.047
response to hexoseGO:000974630.047
positive regulation of cellular processGO:00485222010.047
regulation of endothelial cell proliferationGO:000193610.047
negative regulation of developmental processGO:0051093650.047
oxoacid metabolic processGO:0043436310.046
cellular response to extracellular stimulusGO:003166820.045
regulation of multicellular organism growthGO:004001440.045
regulation of biological qualityGO:00650082630.044
cellular amino acid metabolic processGO:000652070.043
embryonic skeletal system morphogenesisGO:0048704930.043
negative regulation of signalingGO:0023057960.042
response to organic substanceGO:00100331530.041
developmental growth involved in morphogenesisGO:0060560860.041
regulation of signal transductionGO:00099662250.041
regulation of rna biosynthetic processGO:20011412130.041
positive regulation of cell substrate adhesionGO:001081110.040
growth plate cartilage developmentGO:000341720.040
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.040
locomotionGO:00400113130.040
cell projection organizationGO:00300302840.039
negative regulation of protein maturationGO:1903318100.039
growthGO:00400071740.039
chondrocyte developmentGO:000206340.039
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.039
tube morphogenesisGO:00352393490.038
response to glucoseGO:000974930.038
neurological system processGO:0050877620.038
negative regulation of macromolecule metabolic processGO:0010605760.038
positive regulation of canonical wnt signaling pathwayGO:009026340.037
regulation of cellular amine metabolic processGO:003323800.037
limb bud formationGO:006017420.037
larval developmentGO:000216420.036
response to axon injuryGO:0048678140.036
Mouse
negative regulation of map kinase activityGO:004340720.036
positive regulation of multicellular organismal processGO:0051240520.036
positive regulation of biological processGO:00485182530.036
chemotaxisGO:00069351040.036
developmental growthGO:00485891660.036
positive regulation of signal transductionGO:0009967560.036
cellular macromolecule biosynthetic processGO:00346452240.035
endochondral bone morphogenesisGO:006035080.035
bone morphogenesisGO:0060349110.035
cellular response to endogenous stimulusGO:0071495680.035
negative regulation of chemotaxisGO:005092240.035
epithelial to mesenchymal transitionGO:0001837210.035
extracellular matrix constituent secretionGO:007027830.034
regulation of programmed cell deathGO:00430671010.034
response to corticosteroidGO:003196010.034
regulation of rna metabolic processGO:00512522240.033
erk1 and erk2 cascadeGO:007037140.033
negative regulation of cell proliferationGO:000828580.033
regulation of epithelial to mesenchymal transitionGO:001071730.032
transportGO:00068102200.032
cell projection assemblyGO:0030031640.031
negative regulation of intracellular signal transductionGO:1902532220.031
regulation of erk1 and erk2 cascadeGO:007037240.031
response to external stimulusGO:00096052640.031
negative regulation of cell communicationGO:0010648960.031
urogenital system developmentGO:0001655970.031
single organism metabolic processGO:00447102170.031
skeletal muscle organ developmentGO:0060538780.030
heart developmentGO:00075073130.030
cartilage development involved in endochondral bone morphogenesisGO:006035180.030
regulation of peptidase activityGO:0052547230.030
cell motilityGO:00488702440.029
macromolecule biosynthetic processGO:00090592270.029
positive regulation of metabolic processGO:00098931080.029
muscle organ developmentGO:00075171010.029
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315470.029
rna biosynthetic processGO:00327741810.029
response to vitaminGO:003327330.029
nucleobase containing compound biosynthetic processGO:00346542050.029
regulation of bmp signaling pathwayGO:0030510390.028
muscle attachmentGO:001620390.028
photoreceptor cell fate commitmentGO:004655210.028
regulation of nucleobase containing compound metabolic processGO:00192192500.028
nitrogen compound metabolic processGO:00068073190.028
mesoderm developmentGO:0007498880.028
positive regulation of protein kinase b signalingGO:005189710.028
regulation of cellular amino acid metabolic processGO:000652100.027
determination of heart left right asymmetryGO:00613711170.027
specification of symmetryGO:00097992040.027
positive regulation of gene expressionGO:0010628710.027
regulation of apoptotic processGO:0042981980.027
regulation of macromolecule metabolic processGO:00602553170.027
enzyme linked receptor protein signaling pathwayGO:00071671060.026
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.026
regulation of stem cell differentiationGO:200073640.026
cellular response to retinoic acidGO:007130010.025
positive regulation of response to stimulusGO:0048584800.025
cellular component movementGO:00069283350.025
positive regulation of apoptotic signaling pathwayGO:200123510.025
regulation of intracellular signal transductionGO:1902531570.025
positive regulation of macromolecule metabolic processGO:0010604930.025
cartilage morphogenesisGO:0060536130.025
positive regulation of signalingGO:0023056560.024
negative regulation of response to stimulusGO:00485851040.024
regulation of intracellular protein transportGO:003315730.024
skin developmentGO:0043588540.024
transcription dna templatedGO:00063511810.024
embryonic eye morphogenesisGO:0048048300.024
mesenchyme developmentGO:00604851270.024
positive regulation of epithelial cell migrationGO:001063420.024
regulation of cysteine type endopeptidase activityGO:2000116210.024
cell deathGO:00082191210.023
cellular biosynthetic processGO:00442492860.023
embryonic limb morphogenesisGO:003032620.023
regulation of production of molecular mediator of immune responseGO:000270010.023
multicellular organismal water homeostasisGO:005089110.023
renal system processGO:0003014140.023
sympathetic nervous system developmentGO:004848530.022
positive regulation of jnk cascadeGO:004633030.022
transforming growth factor beta receptor signaling pathwayGO:000717970.022
fatty acid transportGO:001590810.022
carboxylic acid metabolic processGO:0019752220.022
cellular amine metabolic processGO:004410620.022
positive regulation of cellular component movementGO:0051272110.022
small molecule metabolic processGO:0044281770.021
protein targeting to nucleusGO:004474430.021
digestive tract morphogenesisGO:00485462310.021
regulation of gene expressionGO:00104682650.021
bleb assemblyGO:003206010.020
embryonic appendage morphogenesisGO:0035113300.020
amine metabolic processGO:000930820.020
primary neural tube formationGO:001402010.020
intramembranous ossificationGO:000195730.020
positive regulation of immune system processGO:0002684170.020
negative regulation of molecular functionGO:0044092230.020
positive regulation of translationGO:004572710.020
regulation of vasculature developmentGO:1901342330.020
digestive tract developmentGO:00485652650.019
regionalizationGO:00030022740.019
striated muscle tissue developmentGO:00147061100.019
protein localization to nucleusGO:003450430.019
bone developmentGO:0060348140.019
protein modification processGO:00362111000.019
regulation of nervous system developmentGO:0051960900.019
homeostatic processGO:00425921420.019
endodermal digestive tract morphogenesisGO:006103120.019
inner ear developmentGO:00488391260.019
mucopolysaccharide metabolic processGO:190351020.019
positive regulation of macromolecule biosynthetic processGO:0010557590.019
negative regulation of cellular metabolic processGO:0031324770.019
organic acid metabolic processGO:0006082310.019
positive regulation of nucleic acid templated transcriptionGO:1903508570.018
establishment of protein localization to organelleGO:007259440.018
protein maturationGO:0051604120.018
regulation of cellular macromolecule biosynthetic processGO:20001122220.018
organic substance transportGO:0071702580.018
cellular nitrogen compound metabolic processGO:00346412900.018
positive regulation of endothelial cell migrationGO:001059520.018
activation of mapk activityGO:000018730.018
ion transportGO:00068111140.018
aromatic compound biosynthetic processGO:00194382170.018
organic cyclic compound biosynthetic processGO:19013622230.018
hemopoiesisGO:00300971830.018
defense response to fungusGO:005083220.018
regulation of anatomical structure morphogenesisGO:00226031300.017
single organism nuclear importGO:190259330.017
cell adhesion mediated by integrinGO:003362710.017
protein import into nucleusGO:000660630.017
protein dephosphorylationGO:000647030.017
positive regulation of immune responseGO:0050778110.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of neurogenesisGO:0050767870.017
proteoglycan metabolic processGO:0006029140.017
regulation of cellular carbohydrate metabolic processGO:001067540.017
regulation of cell activationGO:005086510.017
cognitionGO:005089010.017
neural crest cell developmentGO:0014032620.017
regulation of cytokine biosynthetic processGO:004203510.017
cellular component disassemblyGO:002241110.017
positive regulation of cell activationGO:005086710.017
establishment of localization in cellGO:0051649770.017
positive regulation of cell developmentGO:0010720250.017
positive regulation of leukocyte chemotaxisGO:000269010.017
positive regulation of erk1 and erk2 cascadeGO:007037420.017
regulation of protein localization to nucleusGO:190018020.016
regulation of cell matrix adhesionGO:000195210.016
negative regulation of angiogenesisGO:001652570.016
production of molecular mediator of immune responseGO:000244020.016
negative regulation of cell migrationGO:0030336170.016
cell part morphogenesisGO:00329902460.016
regulation of protein transportGO:005122330.016
apoptotic processGO:00069151160.016
response to abiotic stimulusGO:00096281220.016
single organism transportGO:00447652060.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
cytokine metabolic processGO:004210710.016
proteolysis involved in cellular protein catabolic processGO:005160330.015
tube closureGO:006060610.015
response to copper ionGO:0046688130.015
cytosolic calcium ion transportGO:006040130.015
embryonic cranial skeleton morphogenesisGO:0048701900.015
peptidyl serine modificationGO:001820920.015
negative regulation of cell deathGO:0060548600.015
regulation of synapse organizationGO:005080730.015
cellular response to nutrient levelsGO:003166920.015
heart valve developmentGO:0003170140.015
cell cycle arrestGO:000705010.014
somatic muscle developmentGO:000752540.014
wound healingGO:0042060900.014
myeloid leukocyte migrationGO:0097529120.014
regulation of cell developmentGO:00602841000.014
response to other organismGO:0051707970.014
cell morphogenesisGO:00009022890.014
inner ear morphogenesisGO:0042472630.014
bmp signaling pathwayGO:0030509520.014
positive regulation of blood circulationGO:190352420.014
skin morphogenesisGO:004358970.014
heart valve morphogenesisGO:000317980.014
positive regulation of cell motilityGO:2000147110.014
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.014
heterocycle biosynthetic processGO:00181302150.014
system processGO:00030081850.014
positive regulation of apoptotic processGO:0043065290.014
long chain fatty acid transportGO:001590910.014
determination of left right symmetryGO:00073681790.014
cardiac chamber developmentGO:0003205190.014
cellular component biogenesisGO:00440851780.014
chondroitin sulfate metabolic processGO:003020420.014
regulation of bindingGO:005109830.013
hindbrain developmentGO:0030902910.013
intracellular signal transductionGO:0035556850.013
negative regulation of dna replicationGO:000815620.013
notochord developmentGO:0030903540.013
rna metabolic processGO:00160702190.013
cellular response to vitaminGO:007129510.013
stem cell differentiationGO:00488631170.013
response to bacteriumGO:0009617580.013
regulation of angiogenesisGO:0045765260.013
cellular response to reactive oxygen speciesGO:003461420.013
ceramide biosynthetic processGO:004651310.013
macromolecule modificationGO:00434121110.013
organonitrogen compound metabolic processGO:1901564740.013
nucleobase containing compound metabolic processGO:00061392740.013
osteoblast differentiationGO:000164950.013
single organism biosynthetic processGO:0044711710.013
membrane invaginationGO:001032410.013
gland developmentGO:00487321430.013
regulation of proteolysisGO:0030162240.013
negative regulation of cellular component movementGO:0051271180.013
regulation of molecular functionGO:0065009700.013
septum transversum developmentGO:000334340.013
regulation of cell projection assemblyGO:006049140.013
regulation of reproductive processGO:200024140.012
i kappab kinase nf kappab signalingGO:000724940.012
regulation of apoptotic signaling pathwayGO:2001233120.012
regulation of cellular metabolic processGO:00313233200.012
regulation of dna replicationGO:000627530.012
positive regulation of leukocyte migrationGO:000268720.012
regulation of hydrolase activityGO:0051336280.012
locus ceruleus developmentGO:002170330.012
mapk cascadeGO:0000165180.012
epithelial tube morphogenesisGO:00605621480.012
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003760.012
negative regulation of mapk cascadeGO:004340940.012
pigmentationGO:0043473850.012
circulatory system processGO:0003013870.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
embryonic digestive tract morphogenesisGO:004855730.012
glucose homeostasisGO:004259310.012
positive regulation of catalytic activityGO:0043085250.012
endochondral bone growthGO:000341620.012
neuronal action potentialGO:0019228180.012
positive regulation of molecular functionGO:0044093330.012
cellular protein metabolic processGO:00442671290.012
negative regulation of rna biosynthetic processGO:1902679450.012
basement membrane organizationGO:007171150.011
ventricular cardiac muscle tissue developmentGO:000322930.011
photoreceptor cell fate specificationGO:004370410.011
somitogenesisGO:0001756870.011
cell projection morphogenesisGO:00488582440.011
positive regulation of developmental processGO:0051094500.011
negative regulation of endothelial cell migrationGO:001059610.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of nitrogen compound metabolic processGO:00511712510.011
single organism localizationGO:19025782250.011
stem cell proliferationGO:007208940.011
tissue regenerationGO:0042246740.011
regulation of biosynthetic processGO:00098892500.011
taurine metabolic processGO:001953010.011
hematopoietic or lymphoid organ developmentGO:00485341910.011
nuclear transportGO:005116940.011
phosphorus metabolic processGO:00067931090.011
nuclear importGO:005117030.011
regulation of cellular component movementGO:0051270550.011
stem cell developmentGO:0048864820.011
negative regulation of cellular protein metabolic processGO:0032269160.011
establishment of localizationGO:00512342440.011
immune responseGO:0006955280.011
negative regulation of dna metabolic processGO:005105340.011
multicellular organismal response to stressGO:003355520.011
protein processingGO:0016485120.011
protein importGO:001703830.011
macromolecule localizationGO:0033036540.011
regulation of transcription dna templatedGO:00063552130.010
taxisGO:00423301090.010
cellular ketone metabolic processGO:0042180110.010
antimicrobial humoral responseGO:001973020.010
epithelial tube formationGO:0072175190.010
regulation of cell adhesionGO:0030155150.010
regulation of protein targetingGO:190353320.010
pericardium morphogenesisGO:000334410.010
hard palate developmentGO:006002240.010
neuron projection developmentGO:00311751800.010
endodermal cell differentiationGO:0035987190.010
negative regulation of protein processingGO:0010955100.010
generation of neuronsGO:00486993850.010
cellular response to radiationGO:007147840.010
negative regulation of signal transduction in absence of ligandGO:190109910.010
morphogenesis of an epithelial sheetGO:0002011490.010
phagocytosis engulfmentGO:000691110.010

matn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.108
connective tissue diseaseDOID:6500.108
musculoskeletal system diseaseDOID:1700.108
bone diseaseDOID:008000100.108
neuropathyDOID:87000.039
charcot marie tooth disease type 4DOID:005054100.039
nervous system diseaseDOID:86300.039
charcot marie tooth diseaseDOID:1059500.039
neuromuscular diseaseDOID:44000.039
osteochondrodysplasiaDOID:225600.032
bone development diseaseDOID:008000600.032
bone remodeling diseaseDOID:008000500.016
inherited metabolic disorderDOID:65500.010
disease of metabolismDOID:001466700.010