Danio rerio

24 known processes

ptprub

protein tyrosine phosphatase, receptor type, U, b

(Aliases: RPTP-psi,ptpru,fk66g06,fj42a04,wu:fk66g06,wu:fj42a04)

ptprub biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.085
cellular nitrogen compound biosynthetic processGO:00442712180.069
agingGO:000756820.067
aromatic compound biosynthetic processGO:00194382170.063
stem cell maintenanceGO:001982740.059
heterocycle metabolic processGO:00464832900.058
central nervous system developmentGO:00074173870.057
sensory organ developmentGO:00074233930.056
signal transductionGO:00071654550.052
biosynthetic processGO:00090582940.052
brain developmentGO:00074202930.052
nitrogen compound metabolic processGO:00068073190.051
organic substance biosynthetic processGO:19015762890.050
gene expressionGO:00104672520.050
cellular macromolecule metabolic processGO:00442603910.050
maintenance of locationGO:005123540.050
cellular nitrogen compound metabolic processGO:00346412900.049
regulation of metabolic processGO:00192223590.047
chordate embryonic developmentGO:00430092710.046
cellular biosynthetic processGO:00442492860.046
heterocycle biosynthetic processGO:00181302150.046
macromolecule biosynthetic processGO:00090592270.045
organic cyclic compound biosynthetic processGO:19013622230.045
positive regulation of transportGO:005105020.045
regulation of nucleobase containing compound metabolic processGO:00192192500.045
regulation of primary metabolic processGO:00800903110.045
cellular component movementGO:00069283350.044
organic cyclic compound metabolic processGO:19013603010.044
response to chemicalGO:00422213200.043
regionalizationGO:00030022740.043
cellular macromolecule biosynthetic processGO:00346452240.042
embryonic organ developmentGO:00485683810.041
lipid storageGO:001991510.041
cell surface receptor signaling pathwayGO:00071663250.040
regulation of macromolecule metabolic processGO:00602553170.040
nucleic acid templated transcriptionGO:00976591810.039
regulation of rna metabolic processGO:00512522240.039
regulation of multicellular organismal processGO:00512392770.039
transcription dna templatedGO:00063511810.039
positive regulation of biological processGO:00485182530.039
cell motilityGO:00488702440.039
regulation of nitrogen compound metabolic processGO:00511712510.039
nucleobase containing compound metabolic processGO:00061392740.038
generation of neuronsGO:00486993850.038
neuron differentiationGO:00301823530.038
rna metabolic processGO:00160702190.038
positive regulation of cellular processGO:00485222010.037
nucleic acid metabolic processGO:00903042440.037
response to external stimulusGO:00096052640.037
cell projection organizationGO:00300302840.037
locomotionGO:00400113130.037
regulation of cellular metabolic processGO:00313233200.037
regulation of cellular amino acid metabolic processGO:000652100.037
regulation of multicellular organism growthGO:004001440.036
regulation of cellular biosynthetic processGO:00313262450.036
establishment of protein localization to organelleGO:007259440.036
eye developmentGO:00016542770.036
cellular aromatic compound metabolic processGO:00067252950.036
regulation of cell communicationGO:00106462320.035
neuron developmentGO:00486662620.035
cell migrationGO:00164772370.035
regulation of rna biosynthetic processGO:20011412130.034
regulation of cellular macromolecule biosynthetic processGO:20001122220.034
blood vessel developmentGO:00015682460.034
regulation of nucleic acid templated transcriptionGO:19035062130.034
nucleobase containing compound biosynthetic processGO:00346542050.034
regulation of signalingGO:00230512350.034
rna biosynthetic processGO:00327741810.034
positive regulation of cell cycleGO:004578730.033
embryo development ending in birth or egg hatchingGO:00097922710.033
negative regulation of biological processGO:00485193040.033
nuclear transportGO:005116940.033
multicellular organism growthGO:003526440.033
localization of cellGO:00516742440.032
anterior posterior pattern specificationGO:00099521520.032
single organism nuclear importGO:190259330.032
phagocytosisGO:000690930.032
cellular component morphogenesisGO:00329893360.031
protein importGO:001703830.031
morphogenesis of an epitheliumGO:00020093330.031
head developmentGO:00603223030.031
vasculature developmentGO:00019442780.031
regulation of response to stimulusGO:00485832690.031
protein localization to nucleusGO:003450430.030
protein targeting to nucleusGO:004474430.030
compound eye developmentGO:004874920.030
regulation of transcription dna templatedGO:00063552130.030
transcription from rna polymerase ii promoterGO:0006366800.030
adult behaviorGO:003053420.030
nuclear importGO:005117030.030
regulation of macromolecule biosynthetic processGO:00105562250.030
regulation of signal transductionGO:00099662250.029
amine metabolic processGO:000930820.029
cell morphogenesis involved in differentiationGO:00009041950.029
stem cell proliferationGO:007208940.029
regulation of biosynthetic processGO:00098892500.029
regulation of establishment of protein localizationGO:007020140.029
cell part morphogenesisGO:00329902460.028
nucleocytoplasmic transportGO:000691340.028
protein acetylationGO:000647320.028
regulation of developmental processGO:00507932470.028
cellular amine metabolic processGO:004410620.028
regulation of cytokine productionGO:000181730.028
negative regulation of cellular processGO:00485232830.028
establishment of localizationGO:00512342440.028
regulation of gene expressionGO:00104682650.027
cell projection morphogenesisGO:00488582440.027
immune system processGO:00023762410.027
cell morphogenesisGO:00009022890.027
determination of bilateral symmetryGO:00098552040.026
positive regulation of cellular catabolic processGO:003133130.026
digestive system developmentGO:00551232890.026
single organism metabolic processGO:00447102170.026
positive regulation of cellular component biogenesisGO:004408930.026
regulation of reproductive processGO:200024140.026
cellular ketone metabolic processGO:0042180110.025
cellular response to external stimulusGO:007149620.025
regulation of cellular amine metabolic processGO:003323800.025
protein import into nucleusGO:000660630.025
hemopoiesisGO:00300971830.025
regulation of protein transportGO:005122330.024
regulation of synapse assemblyGO:005196330.024
embryonic organ morphogenesisGO:00485622740.024
sensory organ morphogenesisGO:00905962000.024
heart developmentGO:00075073130.024
internal peptidyl lysine acetylationGO:001839320.024
secondary metabolic processGO:001974830.024
positive regulation of catabolic processGO:000989640.024
guanosine containing compound metabolic processGO:190106840.024
mesenchyme developmentGO:00604851270.024
rhombomere 5 developmentGO:002157140.024
extrinsic apoptotic signaling pathwayGO:009719130.023
protein metabolic processGO:00195381830.023
digestive tract morphogenesisGO:00485462310.023
specification of symmetryGO:00097992040.023
angiogenesisGO:00015251580.023
single organism transportGO:00447652060.023
regulation of epithelial cell proliferationGO:005067830.023
regulation of multicellular organismal developmentGO:20000262230.023
regulation of peptidyl tyrosine phosphorylationGO:005073010.023
regulation of protein targetingGO:190353320.022
blood vessel morphogenesisGO:00485142160.022
camera type eye developmentGO:00430102220.022
internal protein amino acid acetylationGO:000647520.022
regulation of transcription from rna polymerase ii promoterGO:00063571140.022
regulation of protein complex assemblyGO:004325430.022
tube morphogenesisGO:00352393490.022
cellular protein catabolic processGO:004425740.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
regulation of cytoplasmic transportGO:190364940.022
response to drugGO:004249330.022
developmental growthGO:00485891660.021
regulation of cellular ketone metabolic processGO:001056570.021
guanosine containing compound catabolic processGO:190106920.021
cellular response to chemical stimulusGO:00708871570.021
gtp metabolic processGO:004603940.021
peptidyl lysine acetylationGO:001839420.021
regulation of intracellular protein transportGO:003315730.021
cellular response to extracellular stimulusGO:003166820.021
autophagyGO:000691440.021
muscle structure developmentGO:00610611960.021
regulation of cell activationGO:005086510.021
gtp catabolic processGO:000618420.021
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.020
regulation of synapse organizationGO:005080730.020
cell morphogenesis involved in neuron differentiationGO:00486671630.020
regulation of protein import into nucleusGO:004230620.020
neuron projection morphogenesisGO:00488121610.020
segmentationGO:0035282970.020
taxisGO:00423301090.020
positive regulation of cytokine productionGO:000181920.020
cell deathGO:00082191210.020
positive regulation of immune effector processGO:000269930.020
modification dependent macromolecule catabolic processGO:004363230.020
leukocyte proliferationGO:007066110.020
epithelial cell differentiationGO:00308551160.020
cell substrate adhesionGO:003158940.020
cellular response to starvationGO:000926710.020
positive regulation of nitrogen compound metabolic processGO:0051173690.020
synaptic growth at neuromuscular junctionGO:005112420.020
single organism localizationGO:19025782250.019
neuron projection developmentGO:00311751800.019
mononuclear cell proliferationGO:003294310.019
exocytosisGO:000688710.019
single organism organelle organizationGO:19025891990.019
regulation of mrna processingGO:005068430.019
proteolysis involved in cellular protein catabolic processGO:005160330.019
regulation of metal ion transportGO:001095940.019
regulation of nucleocytoplasmic transportGO:004682220.019
carboxylic acid metabolic processGO:0019752220.019
organonitrogen compound metabolic processGO:1901564740.019
embryonic skeletal system developmentGO:0048706970.019
positive regulation of cellular amine metabolic processGO:003324000.019
organic acid metabolic processGO:0006082310.019
modification dependent protein catabolic processGO:001994130.019
regulation of bindingGO:005109830.019
hematopoietic or lymphoid organ developmentGO:00485341910.018
positive regulation of metabolic processGO:00098931080.018
regulation of cell differentiationGO:00455951420.018
dorsal ventral pattern formationGO:00099531250.018
ubiquitin dependent protein catabolic processGO:000651130.018
regulation of biological qualityGO:00650082630.018
negative regulation of catabolic processGO:000989530.018
actin polymerization or depolymerizationGO:000815420.018
cellular response to nutrient levelsGO:003166920.018
retina development in camera type eyeGO:00600411460.018
neuroblast proliferationGO:000740520.018
protein acylationGO:004354330.018
somatic muscle developmentGO:000752540.018
cellular response to lipopolysaccharideGO:007122230.018
cellular component disassemblyGO:002241110.018
ear developmentGO:00435831270.017
hindbrain developmentGO:0030902910.017
ribonucleoside monophosphate catabolic processGO:000915840.017
somatic stem cell maintenanceGO:003501910.017
olfactory bulb developmentGO:002177240.017
skeletal system developmentGO:00015011810.017
regulation of protein ubiquitinationGO:003139630.017
response to stressGO:00069502630.017
oxoacid metabolic processGO:0043436310.017
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.017
negative regulation of signal transductionGO:0009968940.017
olfactory lobe developmentGO:002198840.017
cognitionGO:005089010.017
programmed cell deathGO:00125011190.017
regulation of protein catabolic processGO:004217610.017
deathGO:00162651210.017
cell matrix adhesionGO:000716040.017
outflow tract morphogenesisGO:000315110.017
transportGO:00068102200.017
synaptic target recognitionGO:000803910.017
post embryonic organ developmentGO:004856940.017
regulation of extrinsic apoptotic signaling pathwayGO:200123630.017
wound healingGO:0042060900.017
growthGO:00400071740.016
eye morphogenesisGO:00485921440.016
regulation of stem cell differentiationGO:200073640.016
inner ear developmentGO:00488391260.016
protein secretionGO:000930610.016
production of molecular mediator of immune responseGO:000244020.016
lymphocyte proliferationGO:004665110.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
positive regulation of cell activationGO:005086710.016
regulation of nucleoside metabolic processGO:000911820.016
meiotic nuclear divisionGO:000712640.016
regulation of stem cell proliferationGO:007209120.016
regulation of protein modification by small protein conjugation or removalGO:190332030.016
cellular response to molecule of bacterial originGO:007121930.016
regulation of purine nucleotide catabolic processGO:003312120.016
mitochondrion organizationGO:000700540.016
positive regulation of secretionGO:005104710.016
regulation of protein localization to nucleusGO:190018020.016
enzyme linked receptor protein signaling pathwayGO:00071671060.016
gastrulationGO:00073692080.016
cellular protein metabolic processGO:00442671290.016
phagocytosis engulfmentGO:000691110.016
regulation of synaptic plasticityGO:004816710.016
germ line stem cell maintenanceGO:003071820.016
ameboidal type cell migrationGO:00016671430.016
immune system developmentGO:00025201910.016
female sex differentiationGO:004666040.016
i kappab kinase nf kappab signalingGO:000724940.016
macromolecular complex disassemblyGO:003298410.016
synaptic vesicle transportGO:004848910.016
axonogenesisGO:00074091520.016
regulation of production of molecular mediator of immune responseGO:000270010.016
digestive tract developmentGO:00485652650.016
regulation of meiotic cell cycleGO:005144510.016
response to uvGO:000941130.016
negative regulation of protein phosphorylationGO:000193340.015
lateral inhibitionGO:004633110.015
response to nutrientGO:000758430.015
regulation of synaptic growth at neuromuscular junctionGO:000858210.015
proteasomal protein catabolic processGO:001049820.015
response to organic substanceGO:00100331530.015
sensory perception of chemical stimulusGO:000760630.015
cellular amino acid metabolic processGO:000652070.015
regulation of inflammatory responseGO:005072720.015
intracellular signal transductionGO:0035556850.015
tissue remodelingGO:004877140.015
positive regulation of secretion by cellGO:190353210.015
transmembrane transportGO:00550851200.015
somite developmentGO:0061053960.015
response to carbohydrateGO:000974330.015
positive regulation of notch signaling pathwayGO:004574730.015
cellular response to biotic stimulusGO:007121630.015
positive regulation of cellular metabolic processGO:0031325940.015
membrane invaginationGO:001032410.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
negative regulation of intracellular transportGO:003238730.015
regulation of cell shapeGO:000836010.015
chemotaxisGO:00069351040.015
regulation of cell developmentGO:00602841000.015
gland developmentGO:00487321430.015
response to monosaccharideGO:003428430.014
cellular response to organic substanceGO:00713101050.014
apoptotic processGO:00069151160.014
positive regulation of cell adhesionGO:004578510.014
primary neural tube formationGO:001402010.014
melanin metabolic processGO:000658220.014
neurotransmitter transportGO:000683620.014
carbohydrate homeostasisGO:003350010.014
positive regulation of nucleoside metabolic processGO:004597910.014
peptide transportGO:001583310.014
positive regulation of stress activated mapk cascadeGO:003287430.014
response to glucoseGO:000974930.014
positive regulation of gene expressionGO:0010628710.014
small molecule metabolic processGO:0044281770.014
response to endogenous stimulusGO:0009719830.014
cellular amide metabolic processGO:004360340.014
epithelial tube morphogenesisGO:00605621480.014
atp catabolic processGO:000620040.014
skin developmentGO:0043588540.014
organelle organizationGO:00069962270.014
regulation of circadian rhythmGO:004275240.014
macromolecule modificationGO:00434121110.014
regulation of nucleotide catabolic processGO:003081120.014
protein stabilizationGO:005082120.014
glucose homeostasisGO:004259310.014
g1 s transition of mitotic cell cycleGO:000008210.014
lipid catabolic processGO:001604240.014
positive regulation of nucleobase containing compound metabolic processGO:0045935690.014
embryonic heart tube developmentGO:00350501330.014
response to hexoseGO:000974630.014
embryonic skeletal system morphogenesisGO:0048704930.014
protein complex disassemblyGO:004324110.014
negative regulation of cell communicationGO:0010648960.014
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
sympathetic nervous system developmentGO:004848530.013
development of primary female sexual characteristicsGO:004654540.013
membrane fusionGO:006102520.013
protein localization to plasma membraneGO:007265910.013
cell cycle g1 s phase transitionGO:004484310.013
negative regulation of response to stimulusGO:00485851040.013
positive regulation of nucleotide catabolic processGO:003081310.013
positive regulation of cellular biosynthetic processGO:0031328680.013
cytokinesisGO:000091030.013
positive regulation of cytosolic calcium ion concentrationGO:000720440.013
skeletal system morphogenesisGO:00487051020.013
cellular localizationGO:0051641970.013
regulation of cell deathGO:00109411030.013
camera type eye morphogenesisGO:00485931080.013
negative regulation of secretionGO:005104820.013
fertilizationGO:000956630.013
chemosensory behaviorGO:000763510.013
regulation of reactive oxygen species metabolic processGO:200037720.013
positive regulation of cytoskeleton organizationGO:005149530.013
positive regulation of gtpase activityGO:004354710.013
regulation of nervous system developmentGO:0051960900.013
positive regulation of blood circulationGO:190352420.013
female gonad developmentGO:000858540.013
purine ribonucleoside monophosphate catabolic processGO:000916940.013
muscle organ developmentGO:00075171010.013
regulation of ion transmembrane transporter activityGO:003241220.013
regulation of cell projection assemblyGO:006049140.013
regulation of dendrite morphogenesisGO:004881430.013
b cell activationGO:004211320.013
negative regulation of cytokine productionGO:000181810.013
wnt signaling pathwayGO:0016055800.013
negative regulation of signalingGO:0023057960.013
phosphorus metabolic processGO:00067931090.013
response to topologically incorrect proteinGO:003596620.013
positive regulation of biosynthetic processGO:0009891680.013
regenerationGO:0031099910.013
positive regulation of macromolecule metabolic processGO:0010604930.013
stem cell developmentGO:0048864820.013
positive regulation of rna metabolic processGO:0051254590.013
heart loopingGO:0001947940.013
cytosolic calcium ion transportGO:006040130.012
tube closureGO:006060610.012
positive regulation of transcription dna templatedGO:0045893570.012
regulation of gtp catabolic processGO:003312420.012
stem cell divisionGO:001714510.012
macroautophagyGO:001623610.012
regulation of neural precursor cell proliferationGO:200017730.012
determination of left right symmetryGO:00073681790.012
negative regulation of protein transportGO:005122430.012
positive regulation of response to stimulusGO:0048584800.012
rhombomere 6 developmentGO:002157240.012
axon developmentGO:00615641660.012
golgi vesicle transportGO:004819330.012
organelle fusionGO:004828430.012
protein homooligomerizationGO:005126030.012
skeletal muscle organ developmentGO:0060538780.012
embryonic limb morphogenesisGO:003032620.012
negative regulation of cytoplasmic transportGO:190365020.012
single fertilizationGO:000733830.012
lens development in camera type eyeGO:0002088220.012
regulation of tube sizeGO:003515020.012
regulation of protein bindingGO:004339330.012
endosomal transportGO:001619720.012
kidney developmentGO:0001822920.012
stem cell differentiationGO:00488631170.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
small molecule catabolic processGO:004428230.012
hormone transportGO:000991420.012
establishment of synaptic vesicle localizationGO:009748010.012
establishment of protein localization to plasma membraneGO:009000210.012
regulation of programmed cell deathGO:00430671010.012
nucleoside monophosphate catabolic processGO:000912540.012
positive regulation of jnk cascadeGO:004633030.012
glial cell proliferationGO:001400940.012
regulation of neurogenesisGO:0050767870.012
negative regulation of sequestering of calcium ionGO:005128340.012
embryonic cranial skeleton morphogenesisGO:0048701900.012
regulation of endothelial cell proliferationGO:000193610.012
peptidyl serine phosphorylationGO:001810510.012
forebrain developmentGO:0030900960.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
cilium morphogenesisGO:0060271850.012
interspecies interaction between organismsGO:004441940.012
muscle cell differentiationGO:00426921390.012
convergent extensionGO:00600261180.012
response to woundingGO:00096111160.012
cellular carbohydrate metabolic processGO:004426240.012
regulation of dendrite developmentGO:005077330.012
regulation of gtpase activityGO:004308720.012
single organism membrane fusionGO:004480120.012
response to alkaloidGO:004327920.011
heart morphogenesisGO:00030071560.011
regulation of apoptotic processGO:0042981980.011
regulation of blood vessel sizeGO:005088020.011
signal transduction in absence of ligandGO:003803410.011
epidermis developmentGO:0008544480.011
regulation of anatomical structure morphogenesisGO:00226031300.011
phosphate containing compound metabolic processGO:00067961080.011
embryonic heart tube morphogenesisGO:00031431080.011
negative regulation of synapse assemblyGO:005196420.011
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.011
negative regulation of protein localization to nucleusGO:190018120.011
mesenchymal cell differentiationGO:0048762870.011
positive regulation of map kinase activityGO:004340630.011
rna localizationGO:000640340.011
hormone secretionGO:004687920.011
reactive oxygen species biosynthetic processGO:190340910.011
neuron neuron synaptic transmissionGO:000727010.011
positive regulation of gtp catabolic processGO:003312610.011
negative regulation of dna metabolic processGO:005105340.011
actin filament based movementGO:003004810.011
antimicrobial humoral responseGO:001973020.011
mesenchymal cell developmentGO:0014031780.011
positive regulation of rna biosynthetic processGO:1902680570.011
regulation of exocytosisGO:001715710.011
positive regulation of macromolecule biosynthetic processGO:0010557590.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.011
negative regulation of cellular catabolic processGO:003133030.011
response to abiotic stimulusGO:00096281220.011
regulation of autophagyGO:001050630.011
regulation of cell substrate adhesionGO:001081010.011
cellular protein modification processGO:00064641000.011
cell killingGO:000190620.011
entrainment of circadian clockGO:000964920.011
regulation of response to biotic stimulusGO:000283120.011
cellular response to reactive oxygen speciesGO:003461420.011
myeloid cell differentiationGO:0030099860.011
skeletal muscle tissue developmentGO:0007519670.011
centrosome organizationGO:005129710.011
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.011
developmental growth involved in morphogenesisGO:0060560860.011
negative regulation of mapk cascadeGO:004340940.011
lamellipodium organizationGO:009758110.011
protein complex localizationGO:003150310.011
determination of heart left right asymmetryGO:00613711170.011
erk1 and erk2 cascadeGO:007037140.011
regulation of sodium ion transportGO:000202820.011
negative regulation of epithelial cell proliferationGO:005068010.011
canonical wnt signaling pathwayGO:0060070480.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
cytoplasm organizationGO:000702840.011
sequestering of calcium ionGO:005120830.011
axon guidanceGO:0007411860.011
somitogenesisGO:0001756870.011
water homeostasisGO:003010440.010
spermatid developmentGO:000728620.010
regulation of transporter activityGO:003240920.010
ion transportGO:00068111140.010
startle responseGO:000196440.010
negative regulation of kinase activityGO:003367340.010
mesoderm developmentGO:0007498880.010
positive regulation of apoptotic signaling pathwayGO:200123510.010
protein modification processGO:00362111000.010
regulation of transmembrane transporter activityGO:002289820.010
symbiosis encompassing mutualism through parasitismGO:004440340.010
neural crest cell differentiationGO:0014033720.010
regulation of cellular component organizationGO:0051128860.010
positive regulation of small gtpase mediated signal transductionGO:005105710.010
embryonic hemopoiesisGO:0035162530.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010

ptprub disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.029
nervous system diseaseDOID:86300.016
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
immune system diseaseDOID:291400.012
disease of metabolismDOID:001466700.011
organ system cancerDOID:005068600.011
sensory system diseaseDOID:005015500.010