Danio rerio

31 known processes

nek2

NIMA (never in mitosis gene a)-related kinase 2

(Aliases: zgc:55602,MGC55602)

nek2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of biological processGO:00485193040.172
Human
larval developmentGO:000216420.156
mitotic cell cycle embryonicGO:004544820.101
organelle organizationGO:00069962270.093
Human Mouse Fly
regulation of transcription dna templatedGO:00063552130.092
microtubule organizing center organizationGO:003102310.089
Human
regulation of nitrogen compound metabolic processGO:00511712510.084
nucleobase containing compound biosynthetic processGO:00346542050.081
organic cyclic compound biosynthetic processGO:19013622230.075
regulation of nucleic acid templated transcriptionGO:19035062130.075
negative regulation of cellular processGO:00485232830.074
Human
gene expressionGO:00104672520.074
Fly
nucleic acid templated transcriptionGO:00976591810.072
regulation of metabolic processGO:00192223590.070
Fly
cytokinesisGO:000091030.068
tube morphogenesisGO:00352393490.067
positive regulation of cell cycleGO:004578730.065
cellular nitrogen compound biosynthetic processGO:00442712180.062
cellular macromolecule metabolic processGO:00442603910.062
Human Yeast Mouse Fly
regulation of gene expressionGO:00104682650.061
Fly
cytoskeleton dependent cytokinesisGO:006164030.058
rna biosynthetic processGO:00327741810.058
nucleobase containing compound metabolic processGO:00061392740.057
rna metabolic processGO:00160702190.056
macromolecule biosynthetic processGO:00090592270.056
regulation of macromolecule biosynthetic processGO:00105562250.056
maintenance of locationGO:005123540.056
Human
transcription dna templatedGO:00063511810.055
regulation of rna biosynthetic processGO:20011412130.054
regulation of cellular biosynthetic processGO:00313262450.053
cellular nitrogen compound metabolic processGO:00346412900.052
regulation of macromolecule metabolic processGO:00602553170.052
Fly
regulation of bindingGO:005109830.050
Mouse
single organism organelle organizationGO:19025891990.050
Human Mouse Fly
digestive system developmentGO:00551232890.050
heart developmentGO:00075073130.047
regulation of rna metabolic processGO:00512522240.046
agingGO:000756820.046
organic substance biosynthetic processGO:19015762890.045
cellular macromolecule biosynthetic processGO:00346452240.045
heterocycle biosynthetic processGO:00181302150.045
aromatic compound biosynthetic processGO:00194382170.045
cell substrate adhesionGO:003158940.044
regulation of developmental processGO:00507932470.044
negative regulation of macromolecule biosynthetic processGO:0010558480.043
determination of bilateral symmetryGO:00098552040.042
single organism nuclear importGO:190259330.042
regulation of primary metabolic processGO:00800903110.042
biosynthetic processGO:00090582940.040
heterocycle metabolic processGO:00464832900.039
cellular protein catabolic processGO:004425740.038
regulation of cellular metabolic processGO:00313233200.037
cellular aromatic compound metabolic processGO:00067252950.037
regulation of chromosome segregationGO:005198310.036
Human
embryonic organ developmentGO:00485683810.036
regulation of cell communicationGO:00106462320.036
Fly
establishment of localizationGO:00512342440.035
cellular protein metabolic processGO:00442671290.035
Human Yeast Mouse Fly
organic cyclic compound metabolic processGO:19013603010.035
cellular biosynthetic processGO:00442492860.034
protein localization to nucleusGO:003450430.033
central nervous system developmentGO:00074173870.033
protein polyubiquitinationGO:000020940.033
digestive tract morphogenesisGO:00485462310.032
regulation of intracellular protein transportGO:003315730.032
nucleic acid metabolic processGO:00903042440.032
determination of left right symmetryGO:00073681790.032
regulation of establishment of protein localizationGO:007020140.032
establishment of protein localization to organelleGO:007259440.032
adult behaviorGO:003053420.031
regulation of protein transportGO:005122330.031
mitotic cytokinesisGO:000028130.031
eye developmentGO:00016542770.031
modification dependent macromolecule catabolic processGO:004363230.031
ubiquitin dependent protein catabolic processGO:000651130.031
regulation of multicellular organism growthGO:004001440.031
mitotic cell cycleGO:0000278640.031
Mouse Fly
negative regulation of protein complex assemblyGO:003133310.030
positive regulation of biological processGO:00485182530.030
Fly
morphogenesis of an epitheliumGO:00020093330.030
regulation of biological qualityGO:00650082630.030
Human Fly
regulation of microtubule cytoskeleton organizationGO:007050730.030
Human
cellular component movementGO:00069283350.030
nuclear envelope organizationGO:000699820.029
nucleocytoplasmic transportGO:000691340.029
phagocytosisGO:000690930.029
nitrogen compound metabolic processGO:00068073190.028
regulation of protein complex assemblyGO:004325430.028
specification of symmetryGO:00097992040.028
cellular component morphogenesisGO:00329893360.028
protein import into nucleusGO:000660630.028
oocyte maturationGO:000155640.027
negative regulation of mitosisGO:004583930.027
negative regulation of nucleobase containing compound metabolic processGO:0045934590.027
regulation of biosynthetic processGO:00098892500.027
proteolysis involved in cellular protein catabolic processGO:005160330.027
generation of neuronsGO:00486993850.027
positive regulation of transportGO:005105020.027
stem cell proliferationGO:007208940.026
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.026
transcription from rna polymerase ii promoterGO:0006366800.026
multicellular organism growthGO:003526440.026
negative regulation of nuclear divisionGO:005178430.026
nuclear transportGO:005116940.025
locomotionGO:00400113130.025
cellular ketone metabolic processGO:0042180110.025
digestive tract developmentGO:00485652650.024
brain developmentGO:00074202930.024
macromolecular complex disassemblyGO:003298410.024
regulation of cellular macromolecule biosynthetic processGO:20001122220.024
regulation of synapse organizationGO:005080730.023
sensory organ developmentGO:00074233930.023
lipid storageGO:001991510.023
protein modification processGO:00362111000.023
Human Yeast Mouse Fly
microtubule depolymerizationGO:000701910.023
protein acylationGO:004354330.023
protein targeting to nucleusGO:004474430.023
regulation of signal transductionGO:00099662250.023
Fly
positive regulation of cellular component biogenesisGO:004408930.023
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.022
microtubule polymerization or depolymerizationGO:003110930.022
regulation of nucleobase containing compound metabolic processGO:00192192500.022
negative regulation of rna metabolic processGO:0051253480.022
embryo development ending in birth or egg hatchingGO:00097922710.022
Mouse
cellular component disassemblyGO:002241110.022
transportGO:00068102200.022
single organism localizationGO:19025782250.022
Human
developmental growthGO:00485891660.022
regulation of multicellular organismal developmentGO:20000262230.022
regulation of protein targetingGO:190353320.022
amine metabolic processGO:000930820.021
multi organism processGO:00517041340.021
cell motilityGO:00488702440.021
head developmentGO:00603223030.021
protein polymerizationGO:005125840.021
protein importGO:001703830.021
mitotic cell cycle processGO:1903047480.021
Mouse Fly
signal transductionGO:00071654550.021
Fly
negative regulation of cellular biosynthetic processGO:0031327550.021
neuron developmentGO:00486662620.021
protein complex disassemblyGO:004324110.021
negative regulation of nitrogen compound metabolic processGO:0051172590.021
regulation of nucleoside metabolic processGO:000911820.020
positive regulation of cellular catabolic processGO:003133130.020
regulation of transcription from rna polymerase ii promoterGO:00063571140.020
organelle assemblyGO:00709251100.020
Mouse
g2 m transition of mitotic cell cycleGO:000008640.020
regulation of protein modification by small protein conjugation or removalGO:190332030.020
negative regulation of protein phosphorylationGO:000193340.019
proteasomal protein catabolic processGO:001049820.019
regulation of protein complex disassemblyGO:004324410.019
regulation of protein catabolic processGO:004217610.019
embryonic organ morphogenesisGO:00485622740.019
regulation of response to stimulusGO:00485832690.019
Fly
determination of heart left right asymmetryGO:00613711170.019
regulation of cytoplasmic transportGO:190364940.019
negative regulation of gene expressionGO:0010629650.019
peptidyl serine phosphorylationGO:001810510.019
modification dependent protein catabolic processGO:001994130.019
regulation of nucleocytoplasmic transportGO:004682220.019
localization of cellGO:00516742440.018
meiotic nuclear divisionGO:000712640.018
regulation of protein depolymerizationGO:190187910.018
protein localization to microtubule cytoskeletonGO:007269810.018
response to drugGO:004249330.018
heart morphogenesisGO:00030071560.018
mitotic dna integrity checkpointGO:004477440.018
regulation of protein import into nucleusGO:004230620.018
meiosis iGO:000712710.017
positive regulation of nucleoside metabolic processGO:004597910.017
negative regulation of rna biosynthetic processGO:1902679450.017
positive regulation of catabolic processGO:000989640.017
regulation of protein localization to nucleusGO:190018020.017
response to external stimulusGO:00096052640.017
cell cycle processGO:0022402530.017
Human Mouse Fly
positive regulation of cytoskeleton organizationGO:005149530.017
regulation of protein ubiquitinationGO:003139630.017
neuroblast proliferationGO:000740520.017
negative regulation of nucleic acid templated transcriptionGO:1903507450.017
regulation of reactive oxygen species metabolic processGO:200037720.016
cell morphogenesisGO:00009022890.016
lateral inhibitionGO:004633110.016
regionalizationGO:00030022740.016
small gtpase mediated signal transductionGO:000726480.016
neuron differentiationGO:00301823530.016
gtp catabolic processGO:000618420.016
growthGO:00400071740.016
cellular response to biotic stimulusGO:007121630.015
membrane invaginationGO:001032410.015
epithelial tube morphogenesisGO:00605621480.015
gastrulationGO:00073692080.015
stem cell maintenanceGO:001982740.015
regulation of cell cycleGO:0051726520.015
Fly
positive regulation of dna metabolic processGO:005105410.015
regulation of protein bindingGO:004339330.015
mitotic dna damage checkpointGO:004477340.015
regulation of cytokine productionGO:000181730.014
negative regulation of macromolecule metabolic processGO:0010605760.014
regulation of reproductive processGO:200024140.014
cellular amine metabolic processGO:004410620.014
guanosine containing compound catabolic processGO:190106920.014
regulation of cellular amino acid metabolic processGO:000652100.014
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.014
negative regulation of metabolic processGO:0009892860.014
positive regulation of nitrogen compound metabolic processGO:0051173690.014
single organism membrane fusionGO:004480120.014
convergent extensionGO:00600261180.014
secondary metabolic processGO:001974830.014
ameboidal type cell migrationGO:00016671430.014
protein metabolic processGO:00195381830.013
Human Yeast Mouse Fly
protein depolymerizationGO:005126110.013
peptidyl serine modificationGO:001820920.013
cellular component assemblyGO:00226071700.013
Mouse
positive regulation of nucleotide catabolic processGO:003081310.013
regulation of gtpase activityGO:004308720.013
cell cycle g2 m phase transitionGO:004483940.013
centrosome organizationGO:005129710.013
Human
cellular component assembly involved in morphogenesisGO:00109271070.013
g2 dna damage checkpointGO:003157230.013
negative regulation of biosynthetic processGO:0009890550.013
regulation of cellular component movementGO:0051270550.013
regulation of meiotic cell cycleGO:005144510.013
cellular extravasationGO:004512310.013
cellular response to extracellular stimulusGO:003166820.012
cytokinetic processGO:003250620.012
single fertilizationGO:000733830.012
phagocytosis engulfmentGO:000691110.012
g1 s transition of mitotic cell cycleGO:000008210.012
regulation of purine nucleotide catabolic processGO:003312120.012
organic acid metabolic processGO:0006082310.012
microtubule based processGO:0007017600.012
Human Mouse
positive regulation of purine nucleotide catabolic processGO:003312310.012
positive regulation of cell divisionGO:005178120.012
single organism transportGO:00447652060.012
regulation of cellular protein catabolic processGO:190336210.012
regulation of signalingGO:00230512350.012
Fly
cell projection organizationGO:00300302840.012
negative regulation of transcription dna templatedGO:0045892450.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
negative regulation of kinase activityGO:003367340.012
meiotic cell cycle processGO:190304630.012
gtp metabolic processGO:004603940.012
regulation of nucleotide catabolic processGO:003081120.012
translational initiationGO:000641330.012
regulation of dendrite developmentGO:005077330.012
primary neural tube formationGO:001402010.012
phosphorylationGO:0016310690.012
Human Yeast Mouse Fly
regulation of cell differentiationGO:00455951420.012
regulation of locomotionGO:0040012550.012
spermatid differentiationGO:004851520.011
nuclear exportGO:005116810.011
negative regulation of cellular metabolic processGO:0031324770.011
regulation of neurogenesisGO:0050767870.011
negative regulation of mapk cascadeGO:004340940.011
peptidyl lysine acetylationGO:001839420.011
positive regulation of cellular amine metabolic processGO:003324000.011
regulation of nervous system developmentGO:0051960900.011
carboxylic acid metabolic processGO:0019752220.011
establishment of endothelial barrierGO:006102830.011
reproductionGO:0000003400.011
protein acetylationGO:000647320.011
cellular protein complex disassemblyGO:004362410.011
meiosis iiGO:000713510.011
protein complex subunit organizationGO:0071822460.011
Mouse
centrosome cycleGO:000709810.011
Human
female sex differentiationGO:004666040.011
cell cycle g1 s phase transitionGO:004484310.011
maternal determination of anterior posterior axis embryoGO:000835840.011
regulation of synaptic plasticityGO:004816710.011
regulation of dna replicationGO:000627530.011
cell cycle arrestGO:000705010.011
negative regulation of chromosome organizationGO:200125110.010
interspecies interaction between organismsGO:004441940.010
spermatid developmentGO:000728620.010
sensory organ morphogenesisGO:00905962000.010
internal protein amino acid acetylationGO:000647520.010
regulation of cell deathGO:00109411030.010
regulation of cell shapeGO:000836010.010
positive regulation of metabolic processGO:00098931080.010
autophagyGO:000691440.010
single organism metabolic processGO:00447102170.010
embryonic heart tube morphogenesisGO:00031431080.010
ras protein signal transductionGO:000726570.010
regulation of translational initiationGO:000644610.010
cytoskeleton organizationGO:0007010960.010
Human Mouse
protein localization to plasma membraneGO:007265910.010

nek2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018