IMP: Integrative Multi-species Prediction

Danio rerio

31 known processes

tnni2a.4

troponin I, skeletal, fast 2a.4

(Aliases: hm:zehn0173,tropI-1d,tnni2,zgc:86800)

ZFIN: ZDB-GENE-040625-119
Ensembl: ENSDARG00000029069
Entrez: 494164
UniProtKB: Q0D2W2

Process Predictions
Disease Predictions

tnni2a.4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
organelle assembly	GO:0070925	110	0.966
actomyosin structure organization	GO:0031032	53	0.964
myofibril assembly	GO:0030239	48	0.962
cellular component assembly involved in morphogenesis	GO:0010927	107	0.957
muscle cell development	GO:0055001	115	0.939
striated muscle cell development	GO:0055002	108	0.922
muscle structure development	GO:0061061	196	0.912
muscle cell differentiation	GO:0042692	139	0.901
striated muscle cell differentiation	GO:0051146	129	0.887
regulation of nucleotide catabolic process	GO:0030811	2	0.876
larval development	GO:0002164	2	0.861	Worm
actin filament based process	GO:0030029	64	0.828
ribonucleoside monophosphate catabolic process	GO:0009158	4	0.817
regulation of purine nucleotide catabolic process	GO:0033121	2	0.801
muscle system process	GO:0003012	20	0.778	Human Worm
striated muscle tissue development	GO:0014706	110	0.747	Fly
actin cytoskeleton organization	GO:0030036	63	0.741
cellular component morphogenesis	GO:0032989	336	0.728
heart process	GO:0003015	71	0.709	Fly
regulation of muscle contraction	GO:0006937	3	0.708
heart morphogenesis	GO:0003007	156	0.707
purine nucleoside monophosphate catabolic process	GO:0009128	4	0.702
cardiac muscle cell differentiation	GO:0055007	30	0.685
nucleoside monophosphate catabolic process	GO:0009125	4	0.684
purine ribonucleoside monophosphate catabolic process	GO:0009169	4	0.670
ventricular cardiac muscle tissue morphogenesis	GO:0055010	2	0.641
atp catabolic process	GO:0006200	4	0.633
sarcomere organization	GO:0045214	26	0.629	Worm Fly
striated muscle myosin thick filament assembly	GO:0071688	6	0.610
skeletal muscle thin filament assembly	GO:0030240	4	0.606
cellular component assembly	GO:0022607	170	0.595
regulation of nucleoside metabolic process	GO:0009118	2	0.588
cytoskeleton organization	GO:0007010	96	0.583
cellular component biogenesis	GO:0044085	178	0.579
heart development	GO:0007507	313	0.572	Fly
transmembrane transport	GO:0055085	120	0.564
somatic muscle development	GO:0007525	4	0.557
cytokinesis	GO:0000910	3	0.554
skeletal myofibril assembly	GO:0014866	7	0.515
heart contraction	GO:0060047	71	0.497	Fly
single organism organelle organization	GO:1902589	199	0.485
muscle fiber development	GO:0048747	52	0.477
organelle organization	GO:0006996	227	0.470
regulation of biological quality	GO:0065008	263	0.461	Fly
regulation of hydrolase activity	GO:0051336	28	0.410
regulation of heart contraction	GO:0008016	32	0.408
regulation of system process	GO:0044057	40	0.408
generation of neurons	GO:0048699	385	0.400	Worm
skeletal muscle tissue development	GO:0007519	67	0.397	Fly
cardiac cell development	GO:0055006	21	0.380
cellular biosynthetic process	GO:0044249	286	0.366	Human
neuron projection development	GO:0031175	180	0.362	Worm
system process	GO:0003008	185	0.358	Human Worm Fly
organic substance biosynthetic process	GO:1901576	289	0.354	Human
muscle contraction	GO:0006936	18	0.347	Human Worm
skeletal muscle contraction	GO:0003009	5	0.346	Human
ion transport	GO:0006811	114	0.334
cytoskeleton dependent cytokinesis	GO:0061640	3	0.306
neuron differentiation	GO:0030182	353	0.304	Worm
regulation of purine nucleotide metabolic process	GO:1900542	17	0.300
muscle organ development	GO:0007517	101	0.300	Fly
skeletal muscle organ development	GO:0060538	78	0.295	Fly
myosin filament organization	GO:0031033	6	0.286
ventricular cardiac muscle tissue development	GO:0003229	3	0.285
cardiac muscle tissue development	GO:0048738	48	0.270	Fly
somitogenesis	GO:0001756	87	0.263
ventricular cardiac myofibril assembly	GO:0055005	4	0.258
ion transmembrane transport	GO:0034220	91	0.257
voluntary skeletal muscle contraction	GO:0003010	4	0.221
morphogenesis of an epithelium	GO:0002009	333	0.208
reproduction	GO:0000003	40	0.205	Worm
axonogenesis	GO:0007409	152	0.202	Worm
post embryonic morphogenesis	GO:0009886	4	0.200	Worm
establishment of localization	GO:0051234	244	0.199
homeostatic process	GO:0042592	142	0.198	Fly
regulation of blood circulation	GO:1903522	32	0.196
macromolecular complex assembly	GO:0065003	35	0.189
skeletal muscle fiber development	GO:0048741	35	0.185
cellular amino acid biosynthetic process	GO:0008652	2	0.183
actin filament based movement	GO:0030048	1	0.182
cation homeostasis	GO:0055080	33	0.179
chordate embryonic development	GO:0043009	271	0.178
nitrogen compound metabolic process	GO:0006807	319	0.177	Human
cardiac muscle cell development	GO:0055013	20	0.175
maintenance of location	GO:0051235	4	0.175
muscle tissue development	GO:0060537	110	0.174	Fly
regulation of nucleotide metabolic process	GO:0006140	17	0.172
twitch skeletal muscle contraction	GO:0014721	4	0.170
transport	GO:0006810	220	0.169
cardiocyte differentiation	GO:0035051	44	0.169
purine nucleotide metabolic process	GO:0006163	27	0.166
chemical homeostasis	GO:0048878	49	0.162
locomotion	GO:0040011	313	0.162	Worm
cation transport	GO:0006812	81	0.160
regulation of cellular metabolic process	GO:0031323	320	0.159	Human
cell projection organization	GO:0030030	284	0.158	Worm
lipid storage	GO:0019915	1	0.158
cellular macromolecular complex assembly	GO:0034622	24	0.156
myosin filament assembly	GO:0031034	6	0.155
purine ribonucleoside monophosphate metabolic process	GO:0009167	5	0.153
regulation of transmembrane transport	GO:0034762	18	0.153
locomotory behavior	GO:0007626	34	0.143
directional locomotion	GO:0033058	1	0.138	Worm
cardiac muscle tissue morphogenesis	GO:0055008	7	0.137
blood circulation	GO:0008015	87	0.137	Fly
striated muscle contraction	GO:0006941	12	0.131	Human
fatty acid catabolic process	GO:0009062	1	0.131
cellular protein complex assembly	GO:0043623	19	0.127
organic substance catabolic process	GO:1901575	28	0.126
post embryonic organ development	GO:0048569	4	0.123
heterocycle metabolic process	GO:0046483	290	0.121	Human
embryo development ending in birth or egg hatching	GO:0009792	271	0.120	Worm
protein complex assembly	GO:0006461	30	0.115
behavior	GO:0007610	74	0.115	Worm
calcium ion homeostasis	GO:0055074	19	0.113
response to stress	GO:0006950	263	0.112
positive regulation of cellular catabolic process	GO:0031331	3	0.112
regulation of muscle system process	GO:0090257	5	0.111
positive regulation of transport	GO:0051050	2	0.109
divalent inorganic cation homeostasis	GO:0072507	22	0.108
metal ion homeostasis	GO:0055065	26	0.107
adult behavior	GO:0030534	2	0.107
regulation of multicellular organismal process	GO:0051239	277	0.104
muscle organ morphogenesis	GO:0048644	8	0.102
phosphorus metabolic process	GO:0006793	109	0.102
multi organism process	GO:0051704	134	0.102	Worm
somite development	GO:0061053	96	0.101
embryonic heart tube development	GO:0035050	133	0.099
multi organism reproductive process	GO:0044703	36	0.098	Worm
glycosyl compound metabolic process	GO:1901657	11	0.098
regulation of response to stimulus	GO:0048583	269	0.098
myotube differentiation	GO:0014902	45	0.098
mitotic cell cycle process	GO:1903047	48	0.097
reproductive process	GO:0022414	40	0.096	Worm
purine ribonucleotide metabolic process	GO:0009150	27	0.094
catabolic process	GO:0009056	32	0.092
actin filament organization	GO:0007015	15	0.085
regulation of ion transmembrane transporter activity	GO:0032412	2	0.084
single organism localization	GO:1902578	225	0.084
protein complex biogenesis	GO:0070271	30	0.082
er nucleus signaling pathway	GO:0006984	2	0.081
organic cyclic compound metabolic process	GO:1901360	301	0.079	Human
cellular cation homeostasis	GO:0030003	17	0.079
ribonucleotide metabolic process	GO:0009259	27	0.075
heart looping	GO:0001947	94	0.074
cellular nitrogen compound metabolic process	GO:0034641	290	0.074	Human
positive regulation of catabolic process	GO:0009896	4	0.074
programmed cell death	GO:0012501	119	0.072
anatomical structure homeostasis	GO:0060249	36	0.071	Fly
positive regulation of purine nucleotide catabolic process	GO:0033123	1	0.070
regulation of metabolic process	GO:0019222	359	0.070	Human
positive regulation of nucleoside metabolic process	GO:0045979	1	0.070
cardiac chamber development	GO:0003205	19	0.070
cell cycle process	GO:0022402	53	0.069
protein metabolic process	GO:0019538	183	0.069
protein complex subunit organization	GO:0071822	46	0.068
cardiac ventricle development	GO:0003231	9	0.068
signal transduction	GO:0007165	455	0.067
regulation of molecular function	GO:0065009	70	0.066
regulation of reproductive process	GO:2000241	4	0.066
reactive nitrogen species metabolic process	GO:2001057	0	0.066
cell projection morphogenesis	GO:0048858	244	0.065	Worm
regulation of nitrogen compound metabolic process	GO:0051171	251	0.065	Human
regulation of striated muscle contraction	GO:0006942	2	0.065
cell substrate adhesion	GO:0031589	4	0.063
fatty acid oxidation	GO:0019395	1	0.063
regulation of catalytic activity	GO:0050790	55	0.062
cell matrix adhesion	GO:0007160	4	0.061
ribose phosphate metabolic process	GO:0019693	27	0.061
cardiac myofibril assembly	GO:0055003	9	0.060
single organism reproductive process	GO:0044702	40	0.059	Worm
response to chemical	GO:0042221	320	0.059
embryonic heart tube morphogenesis	GO:0003143	108	0.058
slow twitch skeletal muscle fiber contraction	GO:0031444	3	0.057
membrane repolarization	GO:0086009	2	0.057
gene expression	GO:0010467	252	0.056	Human
metal ion transport	GO:0030001	58	0.056
regulation of ion transmembrane transport	GO:0034765	18	0.056
cell morphogenesis involved in differentiation	GO:0000904	195	0.055	Worm
regulation of nucleobase containing compound metabolic process	GO:0019219	250	0.055	Human
cellular catabolic process	GO:0044248	27	0.054
regulation of biosynthetic process	GO:0009889	250	0.054	Human
fatty acid beta oxidation	GO:0006635	1	0.053
myotube cell development	GO:0014904	35	0.053
specification of symmetry	GO:0009799	204	0.052
purine containing compound metabolic process	GO:0072521	29	0.052
small molecule metabolic process	GO:0044281	77	0.051
divalent inorganic cation transport	GO:0072511	21	0.051
multicellular organismal movement	GO:0050879	8	0.051	Human
circulatory system process	GO:0003013	87	0.050	Fly
cellular aromatic compound metabolic process	GO:0006725	295	0.049	Human
multicellular organismal reproductive process	GO:0048609	35	0.049	Worm
nucleotide metabolic process	GO:0009117	28	0.049
regulation of nitric oxide mediated signal transduction	GO:0010749	1	0.049
cell division	GO:0051301	20	0.049
regulation of metal ion transport	GO:0010959	4	0.048
immune system process	GO:0002376	241	0.048
aromatic compound catabolic process	GO:0019439	15	0.048
localization of cell	GO:0051674	244	0.047
macromolecule biosynthetic process	GO:0009059	227	0.047	Human
cardiac ventricle morphogenesis	GO:0003208	7	0.047
rna metabolic process	GO:0016070	219	0.046	Human
single organism transport	GO:0044765	206	0.046
regulation of sequestering of calcium ion	GO:0051282	4	0.045
cellular component movement	GO:0006928	335	0.045
developmental growth	GO:0048589	166	0.045
protein localization to nucleus	GO:0034504	3	0.045
cellular nitrogen compound catabolic process	GO:0044270	15	0.045
aging	GO:0007568	2	0.044
nucleobase containing small molecule metabolic process	GO:0055086	32	0.044
cellular response to topologically incorrect protein	GO:0035967	2	0.044
synaptic transmission cholinergic	GO:0007271	4	0.044
endoplasmic reticulum unfolded protein response	GO:0030968	2	0.044
cell cell signaling	GO:0007267	52	0.044
nucleoside metabolic process	GO:0009116	11	0.043
cellular response to organic substance	GO:0071310	105	0.042
sequestering of calcium ion	GO:0051208	3	0.042
cellular metal ion homeostasis	GO:0006875	16	0.042
actin mediated cell contraction	GO:0070252	1	0.041
purine ribonucleoside triphosphate metabolic process	GO:0009205	9	0.040
cellular ion homeostasis	GO:0006873	17	0.040
cardiac chamber morphogenesis	GO:0003206	12	0.040
nucleobase containing compound metabolic process	GO:0006139	274	0.040	Human
response to activity	GO:0014823	14	0.040
regulation of transporter activity	GO:0032409	2	0.040
axon development	GO:0061564	166	0.040	Worm
water homeostasis	GO:0030104	4	0.039
hematopoietic stem cell differentiation	GO:0060218	20	0.039
cardiac muscle fiber development	GO:0048739	3	0.039
organonitrogen compound metabolic process	GO:1901564	74	0.039
multicellular organism reproduction	GO:0032504	35	0.038	Worm
lymphoid lineage cell migration	GO:0097534	4	0.038
ventricular cardiac muscle cell differentiation	GO:0055012	6	0.037
macromolecular complex subunit organization	GO:0043933	74	0.037
regulation of primary metabolic process	GO:0080090	311	0.037	Human
cell motility	GO:0048870	244	0.036
purine ribonucleoside metabolic process	GO:0046128	10	0.035
response to unfolded protein	GO:0006986	2	0.035
cell morphogenesis involved in neuron differentiation	GO:0048667	163	0.035	Worm
neuron neuron synaptic transmission	GO:0007270	1	0.035
regulation of transmembrane transporter activity	GO:0022898	2	0.034
organic acid metabolic process	GO:0006082	31	0.034
muscle cell cellular homeostasis	GO:0046716	5	0.034	Fly
macromolecule catabolic process	GO:0009057	15	0.033
embryonic organ morphogenesis	GO:0048562	274	0.033
neuromuscular synaptic transmission	GO:0007274	2	0.033
protein targeting to nucleus	GO:0044744	3	0.032
ion homeostasis	GO:0050801	41	0.032
nucleoside phosphate metabolic process	GO:0006753	28	0.032
regulation of cell matrix adhesion	GO:0001952	1	0.032
regulation of nucleic acid templated transcription	GO:1903506	213	0.031	Human
muscle tissue morphogenesis	GO:0060415	7	0.031
cellular calcium ion homeostasis	GO:0006874	13	0.031
regulation of blood pressure	GO:0008217	1	0.031
heterocycle catabolic process	GO:0046700	15	0.031
lipid oxidation	GO:0034440	1	0.031
neuron development	GO:0048666	262	0.030	Worm
organic cyclic compound biosynthetic process	GO:1901362	223	0.030	Human
nucleobase containing compound catabolic process	GO:0034655	15	0.029
lymphoid lineage cell migration into thymus	GO:0097535	4	0.029
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	2	0.029
feeding behavior	GO:0007631	5	0.029	Worm
cellular response to unfolded protein	GO:0034620	2	0.029
protein stabilization	GO:0050821	2	0.029
positive regulation of nucleotide catabolic process	GO:0030813	1	0.028
nuclear division	GO:0000280	23	0.028	Fly
transcription dna templated	GO:0006351	181	0.028	Human
reactive oxygen species metabolic process	GO:0072593	6	0.028
cellular homeostasis	GO:0019725	26	0.028	Fly
organic cyclic compound catabolic process	GO:1901361	15	0.028
vasculature development	GO:0001944	278	0.027
cellular chemical homeostasis	GO:0055082	17	0.027
cellular divalent inorganic cation homeostasis	GO:0072503	13	0.027
inorganic cation transmembrane transport	GO:0098662	50	0.026
mitotic cell cycle	GO:0000278	64	0.026
synaptic growth at neuromuscular junction	GO:0051124	2	0.025
nucleocytoplasmic transport	GO:0006913	4	0.025
venous blood vessel morphogenesis	GO:0048845	3	0.025
small molecule catabolic process	GO:0044282	3	0.025
regulation of multicellular organismal development	GO:2000026	223	0.025
pronephros development	GO:0048793	69	0.025
growth plate cartilage morphogenesis	GO:0003422	1	0.024
canonical wnt signaling pathway	GO:0060070	48	0.024
biosynthetic process	GO:0009058	294	0.024	Human
multicellular organism growth	GO:0035264	4	0.024
regulation of calcium ion transport	GO:0051924	2	0.024
nuclear transport	GO:0051169	4	0.024
ribonucleoside metabolic process	GO:0009119	11	0.023
growth	GO:0040007	174	0.023
proteolysis involved in cellular protein catabolic process	GO:0051603	3	0.023
regulation of macromolecule biosynthetic process	GO:0010556	225	0.023	Human
cytokinetic process	GO:0032506	2	0.022
head development	GO:0060322	303	0.022
purine nucleoside triphosphate metabolic process	GO:0009144	9	0.022
cellular localization	GO:0051641	97	0.022
cellular lipid catabolic process	GO:0044242	3	0.022
regulation of protein polymerization	GO:0032271	2	0.022
stem cell division	GO:0017145	1	0.022
intracellular signal transduction	GO:0035556	85	0.021
response to oxygen containing compound	GO:1901700	55	0.021
nucleic acid templated transcription	GO:0097659	181	0.021	Human
ribonucleoside triphosphate metabolic process	GO:0009199	9	0.021
nuclear import	GO:0051170	3	0.021
heterocycle biosynthetic process	GO:0018130	215	0.021	Human
regulation of organ growth	GO:0046620	3	0.021
ribonucleoside monophosphate metabolic process	GO:0009161	5	0.021
anterior posterior pattern specification	GO:0009952	152	0.020
epithelial tube morphogenesis	GO:0060562	148	0.020
regulation of phosphorus metabolic process	GO:0051174	43	0.020
inorganic ion transmembrane transport	GO:0098660	57	0.020
ventricular cardiac muscle cell development	GO:0055015	5	0.020
body morphogenesis	GO:0010171	16	0.020	Worm
negative regulation of gene expression	GO:0010629	65	0.020
enzyme linked receptor protein signaling pathway	GO:0007167	106	0.020
endocardial cushion formation	GO:0003272	2	0.019
single organism cellular localization	GO:1902580	46	0.019
cellular nitrogen compound biosynthetic process	GO:0044271	218	0.019	Human
regulation of cellular component size	GO:0032535	30	0.019
reactive oxygen species biosynthetic process	GO:1903409	1	0.019
atp metabolic process	GO:0046034	5	0.019
purine ribonucleoside triphosphate catabolic process	GO:0009207	6	0.019
single organism nuclear import	GO:1902593	3	0.019
cation transmembrane transport	GO:0098655	65	0.019
tube morphogenesis	GO:0035239	349	0.019
carboxylic acid metabolic process	GO:0019752	22	0.019
regulation of membrane potential	GO:0042391	23	0.019
regulation of rna biosynthetic process	GO:2001141	213	0.019	Human
kidney development	GO:0001822	92	0.018
atrial cardiac myofibril assembly	GO:0055004	2	0.018
phosphate containing compound metabolic process	GO:0006796	108	0.018
cellular macromolecule biosynthetic process	GO:0034645	224	0.018	Human
organophosphate metabolic process	GO:0019637	37	0.018
purine nucleoside metabolic process	GO:0042278	10	0.018
purine ribonucleotide catabolic process	GO:0009154	6	0.018
positive regulation of biological process	GO:0048518	253	0.018	Human
alternative mrna splicing via spliceosome	GO:0000380	1	0.018
macromolecule localization	GO:0033036	54	0.018
cellular macromolecule metabolic process	GO:0044260	391	0.018	Human
regulation of cellular biosynthetic process	GO:0031326	245	0.017	Human
axonal fasciculation	GO:0007413	11	0.017
organic acid catabolic process	GO:0016054	3	0.017
gtp metabolic process	GO:0046039	4	0.017
cell adhesion	GO:0007155	40	0.017
establishment of protein localization to organelle	GO:0072594	4	0.017
purine nucleoside monophosphate metabolic process	GO:0009126	5	0.017
regulation of growth	GO:0040008	42	0.017
cell migration	GO:0016477	237	0.017
modification dependent macromolecule catabolic process	GO:0043632	3	0.017
endocardial cushion morphogenesis	GO:0003203	3	0.017
oxoacid metabolic process	GO:0043436	31	0.016
skeletal system morphogenesis	GO:0048705	102	0.016
regulation of protein import into nucleus	GO:0042306	2	0.016
tissue homeostasis	GO:0001894	25	0.016
neuron recognition	GO:0008038	18	0.016
wnt signaling pathway	GO:0016055	80	0.016
growth plate cartilage development	GO:0003417	2	0.016
sequestering of metal ion	GO:0051238	3	0.016
inositol lipid mediated signaling	GO:0048017	2	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	69	0.015	Human
biological adhesion	GO:0022610	40	0.015
carboxylic acid catabolic process	GO:0046395	3	0.015
nitric oxide mediated signal transduction	GO:0007263	2	0.015
nucleoside monophosphate metabolic process	GO:0009123	6	0.015
response to heat	GO:0009408	6	0.015
regulation of developmental process	GO:0050793	247	0.015
taxis	GO:0042330	109	0.014
hormone secretion	GO:0046879	2	0.014
response to organic substance	GO:0010033	153	0.014
embryonic cranial skeleton morphogenesis	GO:0048701	90	0.014
nucleoside triphosphate metabolic process	GO:0009141	9	0.014
regulation of signaling	GO:0023051	235	0.014
determination of heart left right asymmetry	GO:0061371	117	0.014
regulation of transport	GO:0051049	45	0.014
regulation of catabolic process	GO:0009894	12	0.014
endochondral bone growth	GO:0003416	2	0.014
regulation of protein complex disassembly	GO:0043244	1	0.014
regulation of cell development	GO:0060284	100	0.014
negative regulation of protein serine threonine kinase activity	GO:0071901	2	0.014
cardiac muscle contraction	GO:0060048	6	0.013
positive regulation of cytosolic calcium ion concentration	GO:0007204	4	0.013
purine ribonucleoside catabolic process	GO:0046130	6	0.013
regulation of cell substrate adhesion	GO:0010810	1	0.013
embryonic pattern specification	GO:0009880	44	0.013
pole plasm assembly	GO:0007315	4	0.013
urogenital system development	GO:0001655	97	0.013
regulation of protein targeting	GO:1903533	2	0.013
peptidyl serine phosphorylation	GO:0018105	1	0.012
purine nucleotide catabolic process	GO:0006195	6	0.012
embryonic organ development	GO:0048568	381	0.012
pharyngeal muscle development	GO:0043282	4	0.012
protein import into nucleus	GO:0006606	3	0.012
regulation of cellular macromolecule biosynthetic process	GO:2000112	222	0.012	Human
cell morphogenesis	GO:0000902	289	0.012	Worm
organ growth	GO:0035265	12	0.012
regulation of ion transport	GO:0043269	22	0.012
regulation of alternative mrna splicing via spliceosome	GO:0000381	1	0.012
modification dependent protein catabolic process	GO:0019941	3	0.012
nucleoside catabolic process	GO:0009164	7	0.012
stem cell proliferation	GO:0072089	4	0.012
regulation of cytoplasmic transport	GO:1903649	4	0.012
regulation of heart rate	GO:0002027	5	0.012
connective tissue development	GO:0061448	99	0.012
nucleobase containing compound biosynthetic process	GO:0034654	205	0.012	Human
protein polymerization	GO:0051258	4	0.012
regulation of behavior	GO:0050795	24	0.012
apoptotic process involved in development	GO:1902742	2	0.012
cellular amino acid metabolic process	GO:0006520	7	0.012
determination of bilateral symmetry	GO:0009855	204	0.012
rna biosynthetic process	GO:0032774	181	0.011	Human
cytosolic calcium ion transport	GO:0060401	3	0.011
developmental process involved in reproduction	GO:0003006	27	0.011	Worm
regulation of developmental growth	GO:0048638	38	0.011
nucleic acid metabolic process	GO:0090304	244	0.011	Human
nucleoside phosphate catabolic process	GO:1901292	6	0.011
negative regulation of kinase activity	GO:0033673	4	0.011
actin filament polymerization	GO:0030041	2	0.011
cellular macromolecule localization	GO:0070727	21	0.011
cell surface receptor signaling pathway	GO:0007166	325	0.011
mitotic cytokinesis	GO:0000281	3	0.011
mitochondrion organization	GO:0007005	4	0.011
endocytosis	GO:0006897	16	0.011
response to abiotic stimulus	GO:0009628	122	0.011
carbohydrate derivative metabolic process	GO:1901135	61	0.011
posttranscriptional regulation of gene expression	GO:0010608	14	0.011
negative regulation of metabolic process	GO:0009892	86	0.011
developmental cell growth	GO:0048588	52	0.010
negative regulation of cellular catabolic process	GO:0031330	3	0.010
proteasomal protein catabolic process	GO:0010498	2	0.010
rna localization	GO:0006403	4	0.010
regulation of heart growth	GO:0060420	2	0.010
single organism metabolic process	GO:0044710	217	0.010

tnni2a.4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.302	Human
musculoskeletal system disease	DOID:17	0.302	Human
muscular disease	DOID:0080000	0.265	Human
muscle tissue disease	DOID:66	0.265	Human
myopathy	DOID:423	0.145
cardiovascular system disease	DOID:1287	0.145
heart disease	DOID:114	0.145
cardiomyopathy	DOID:0050700	0.145
intrinsic cardiomyopathy	DOID:0060036	0.128
hypertrophic cardiomyopathy	DOID:11984	0.079
dilated cardiomyopathy	DOID:12930	0.022
autosomal dominant nonsyndromic deafness	DOID:0050564	0.011
auditory system disease	DOID:2742	0.011
sensory system disease	DOID:0050155	0.011
nonsyndromic deafness	DOID:0050563	0.011
nervous system disease	DOID:863	0.011

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