Danio rerio

0 known processes

psmd4b

proteasome (prosome, macropain) 26S subunit, non-ATPase, 4b

(Aliases: psmd4,wu:fc68c04,im:6912672,zgc:110247)

psmd4b biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
modification dependent macromolecule catabolic processGO:004363230.853
Yeast Worm
cellular protein catabolic processGO:004425740.843
Yeast Worm
ubiquitin dependent protein catabolic processGO:000651130.775
Yeast Worm
proteolysis involved in cellular protein catabolic processGO:005160330.690
Yeast Worm
modification dependent protein catabolic processGO:001994130.679
Yeast Worm
agingGO:000756820.601
Worm
cellular macromolecule metabolic processGO:00442603910.450
Yeast Worm Fly
fertilizationGO:000956630.443
single fertilizationGO:000733830.401
regulation of meiotic cell cycleGO:005144510.388
larval developmentGO:000216420.359
Worm
protein polyubiquitinationGO:000020940.346
regulation of metabolic processGO:00192223590.334
Worm Fly
protein metabolic processGO:00195381830.306
Yeast Worm Fly
cellular protein metabolic processGO:00442671290.300
Yeast Worm Fly
meiotic nuclear divisionGO:000712640.245
meiotic cell cycle processGO:190304630.243
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.229
cellular component assemblyGO:00226071700.182
pronuclear migrationGO:003504610.169
proteasomal protein catabolic processGO:001049820.154
organelle organizationGO:00069962270.147
meiotic chromosome segregationGO:004513230.135
cellular macromolecule catabolic processGO:0044265120.133
Yeast Worm
establishment of localizationGO:00512342440.129
signal transductionGO:00071654550.107
positive regulation of cellular component biogenesisGO:004408930.102
chromosome organization involved in meiosisGO:007019210.101
proteolysisGO:0006508380.101
Yeast Worm Fly
cellular catabolic processGO:0044248270.098
Yeast Worm
regulation of protein ubiquitinationGO:003139630.098
Fly
catabolic processGO:0009056320.096
Yeast Worm
regulation of biosynthetic processGO:00098892500.096
positive regulation of biological processGO:00485182530.096
cellular component biogenesisGO:00440851780.095
single organism organelle organizationGO:19025891990.091
positive regulation of protein complex assemblyGO:003133420.091
regulation of protein modification by small protein conjugation or removalGO:190332030.088
Fly
regulation of protein catabolic processGO:004217610.087
regulation of macromolecule metabolic processGO:00602553170.087
Worm Fly
dna templated transcription initiationGO:000635210.087
cell morphogenesisGO:00009022890.084
regulation of primary metabolic processGO:00800903110.083
Fly
protein catabolic processGO:003016370.077
Yeast Worm
multicellular organism growthGO:003526440.077
protein secretionGO:000930610.076
transportGO:00068102200.075
positive regulation of cell cycleGO:004578730.074
embryo development ending in birth or egg hatchingGO:00097922710.073
organic substance catabolic processGO:1901575280.071
Yeast Worm
nitrogen compound metabolic processGO:00068073190.070
positive regulation of metabolic processGO:00098931080.068
regulation of protein complex assemblyGO:004325430.068
response to organic substanceGO:00100331530.067
rna metabolic processGO:00160702190.067
positive regulation of cellular metabolic processGO:0031325940.066
macromolecule catabolic processGO:0009057150.065
Yeast Worm
nucleobase containing compound metabolic processGO:00061392740.065
nucleic acid metabolic processGO:00903042440.065
positive regulation of cellular processGO:00485222010.065
membrane fusionGO:006102520.064
cellular biosynthetic processGO:00442492860.063
regulation of nitrogen compound metabolic processGO:00511712510.063
protein complex assemblyGO:0006461300.063
cellular protein modification processGO:00064641000.063
Fly
regulation of catalytic activityGO:0050790550.063
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.061
protein k63 linked ubiquitinationGO:007053420.061
negative regulation of biological processGO:00485193040.061
Worm
regulation of nucleobase containing compound metabolic processGO:00192192500.061
ribonucleoside monophosphate catabolic processGO:000915840.059
response to stressGO:00069502630.058
Fly
protein modification processGO:00362111000.057
Fly
positive regulation of macromolecule metabolic processGO:0010604930.056
regulation of establishment of protein localizationGO:007020140.056
transcription dna templatedGO:00063511810.055
cellular nitrogen compound metabolic processGO:00346412900.055
regulation of macromolecule biosynthetic processGO:00105562250.054
regulation of cytoplasmic transportGO:190364940.054
regulation of response to stimulusGO:00485832690.051
aromatic compound biosynthetic processGO:00194382170.051
small molecule metabolic processGO:0044281770.050
regulation of rna biosynthetic processGO:20011412130.050
cytokinesisGO:000091030.049
organelle fusionGO:004828430.049
regulation of cell shapeGO:000836010.049
nucleoside monophosphate catabolic processGO:000912540.048
cell projection morphogenesisGO:00488582440.048
nucleic acid templated transcriptionGO:00976591810.048
cellular response to extracellular stimulusGO:003166820.048
nucleobase containing compound biosynthetic processGO:00346542050.047
cell proliferationGO:0008283800.047
organic cyclic compound biosynthetic processGO:19013622230.046
gene expressionGO:00104672520.045
Worm
single organism membrane fusionGO:004480120.044
positive regulation of nitrogen compound metabolic processGO:0051173690.044
macromolecular complex subunit organizationGO:0043933740.043
organic cyclic compound metabolic processGO:19013603010.043
protein modification by small protein conjugation or removalGO:0070647140.043
Fly
blood vessel developmentGO:00015682460.043
heterocycle biosynthetic processGO:00181302150.042
macromolecule modificationGO:00434121110.042
Fly
phagocytosisGO:000690930.042
generation of neuronsGO:00486993850.041
regulation of cellular biosynthetic processGO:00313262450.040
pole plasm assemblyGO:000731540.040
response to external stimulusGO:00096052640.040
cellular aromatic compound metabolic processGO:00067252950.039
macromolecular complex assemblyGO:0065003350.039
negative regulation of cellular processGO:00485232830.039
cellular macromolecular complex assemblyGO:0034622240.039
maintenance of locationGO:005123540.038
regulation of cell communicationGO:00106462320.038
response to abiotic stimulusGO:00096281220.038
microtubule cytoskeleton organization involved in mitosisGO:190285010.037
nuclear migrationGO:000709730.037
regulation of cellular protein catabolic processGO:190336210.037
rna biosynthetic processGO:00327741810.036
neuron projection morphogenesisGO:00488121610.035
mitotic cell cycle processGO:1903047480.035
regulation of developmental processGO:00507932470.035
Worm
cell surface receptor signaling pathwayGO:00071663250.034
regulation of mitotic cell cycleGO:0007346250.033
male meiosisGO:000714020.033
positive regulation of catabolic processGO:000989640.033
response to drugGO:004249330.033
cellular response to external stimulusGO:007149620.033
cellular macromolecule biosynthetic processGO:00346452240.032
regulation of cellular metabolic processGO:00313233200.032
Fly
regulation of nucleocytoplasmic transportGO:004682220.032
cellular protein complex assemblyGO:0043623190.032
cellular nitrogen compound biosynthetic processGO:00442712180.032
protein polymerizationGO:005125840.032
organelle assemblyGO:00709251100.032
negative regulation of response to stimulusGO:00485851040.031
regulation of multicellular organismal processGO:00512392770.031
Worm
response to woundingGO:00096111160.031
single organism localizationGO:19025782250.030
positive regulation of transportGO:005105020.030
cell part morphogenesisGO:00329902460.030
localization within membraneGO:005166810.030
gtp metabolic processGO:004603940.030
negative regulation of protein transportGO:005122430.029
oocyte anterior posterior axis specificationGO:000731440.029
regulation of molecular functionGO:0065009700.029
positive regulation of cellular catabolic processGO:003133130.029
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.029
multi organism processGO:00517041340.028
Worm
locomotionGO:00400113130.028
vasculature developmentGO:00019442780.028
meiosis iiGO:000713510.028
regulation of cell activationGO:005086510.028
autophagyGO:000691440.028
negative regulation of immune responseGO:005077720.028
regulation of rna metabolic processGO:00512522240.027
neuroblast proliferationGO:000740520.027
regulation of cellular component organizationGO:0051128860.027
organic substance transportGO:0071702580.027
guanosine containing compound catabolic processGO:190106920.026
purine ribonucleoside monophosphate catabolic processGO:000916940.026
regulation of cellular protein metabolic processGO:0032268520.026
Fly
cellular process involved in reproduction in multicellular organismGO:0022412280.026
cell cycle g2 m phase transitionGO:004483940.026
cell projection organizationGO:00300302840.026
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.026
phosphate containing compound metabolic processGO:00067961080.026
meiosis iGO:000712710.026
blood vessel morphogenesisGO:00485142160.026
regulation of synaptic growth at neuromuscular junctionGO:000858210.025
cortical cytoskeleton organizationGO:003086510.024
regulation of response to stressGO:0080134360.024
phosphorus metabolic processGO:00067931090.024
response to chemicalGO:00422213200.024
double strand break repairGO:000630230.024
cellular response to nutrient levelsGO:003166920.023
organelle localizationGO:0051640490.023
reproductive processGO:0022414400.023
Worm
negative regulation of mitosisGO:004583930.023
regulation of signalingGO:00230512350.023
negative regulation of cytoplasmic transportGO:190365020.023
gamete generationGO:0007276330.023
Worm
macromolecule biosynthetic processGO:00090592270.023
regulation of cellular macromolecule biosynthetic processGO:20001122220.022
lipid storageGO:001991510.022
multi organism reproductive processGO:0044703360.022
Worm
cytoplasm organizationGO:000702840.022
neuron differentiationGO:00301823530.022
cellular component morphogenesisGO:00329893360.022
transcription from rna polymerase ii promoterGO:0006366800.022
positive regulation of secretion by cellGO:190353210.022
establishment of organelle localizationGO:0051656450.022
single organism metabolic processGO:00447102170.022
ribonucleotide metabolic processGO:0009259270.021
synaptic growth at neuromuscular junctionGO:005112420.021
nuclear transportGO:005116940.021
positive regulation of cell activationGO:005086710.021
nucleocytoplasmic transportGO:000691340.021
organelle fissionGO:0048285230.021
regulation of synapse assemblyGO:005196330.021
cell morphogenesis involved in neuron differentiationGO:00486671630.021
regulation of biological qualityGO:00650082630.021
regulation of synapse organizationGO:005080730.021
regulation of intracellular protein transportGO:003315730.021
sexual reproductionGO:0019953360.021
Worm
regulation of proteolysisGO:0030162240.021
programmed cell deathGO:00125011190.021
cellular response to stressGO:0033554620.020
Fly
regulation of anatomical structure morphogenesisGO:00226031300.020
regulation of protein transportGO:005122330.020
cell motilityGO:00488702440.020
positive regulation of secretionGO:005104710.020
double strand break repair via homologous recombinationGO:000072410.020
regulation of multicellular organism growthGO:004001440.020
organonitrogen compound metabolic processGO:1901564740.020
negative regulation of signalingGO:0023057960.020
g2 m transition of mitotic cell cycleGO:000008640.020
regulation of inflammatory responseGO:005072720.020
establishment of protein localization to organelleGO:007259440.019
positive regulation of transcription dna templatedGO:0045893570.019
regulation of endopeptidase activityGO:0052548230.019
macromolecule localizationGO:0033036540.019
regulation of nucleoside metabolic processGO:000911820.019
stem cell differentiationGO:00488631170.019
mitotic cell cycleGO:0000278640.019
cell cycleGO:0007049930.019
cell morphogenesis involved in differentiationGO:00009041950.019
regulation of mitochondrion organizationGO:001082110.019
heterocycle metabolic processGO:00464832900.019
multicellular organism reproductionGO:0032504350.018
Worm
regulation of transcription from rna polymerase ii promoterGO:00063571140.018
ncrna catabolic processGO:003466110.018
regulation of mrna processingGO:005068430.018
response to temperature stimulusGO:0009266150.018
regulation of transcription dna templatedGO:00063552130.018
chemotaxisGO:00069351040.018
cellular response to starvationGO:000926710.018
organelle transport along microtubuleGO:007238410.018
regionalizationGO:00030022740.018
purine nucleoside monophosphate catabolic processGO:000912840.018
establishment of localization in cellGO:0051649770.017
regulation of mrna splicing via spliceosomeGO:004802430.017
neuron projection developmentGO:00311751800.017
positive regulation of cytoskeleton organizationGO:005149530.017
localization of cellGO:00516742440.017
regulation of protein import into nucleusGO:004230620.017
rna processingGO:0006396250.017
regulation of response to oxidative stressGO:190288220.017
regulation of nucleic acid templated transcriptionGO:19035062130.017
cell migrationGO:00164772370.017
purine nucleotide metabolic processGO:0006163270.017
developmental growthGO:00485891660.017
positive regulation of cytosolic calcium ion concentrationGO:000720440.017
gtp catabolic processGO:000618420.017
i kappab kinase nf kappab signalingGO:000724940.016
positive regulation of gtp catabolic processGO:003312610.016
organic acid metabolic processGO:0006082310.016
single organism transportGO:00447652060.016
regulation of multicellular organismal developmentGO:20000262230.016
Worm
tissue remodelingGO:004877140.016
neuron developmentGO:00486662620.016
recombinational repairGO:000072510.016
positive regulation of protein metabolic processGO:0051247230.016
negative regulation of metabolic processGO:0009892860.016
Worm
regulation of bindingGO:005109830.016
positive regulation of map kinase activityGO:004340630.016
defense responseGO:0006952470.015
reproductionGO:0000003400.015
Worm
regulation of chromosome segregationGO:005198310.015
synaptic vesicle localizationGO:009747910.015
regulation of carbohydrate metabolic processGO:000610940.015
regulation of response to external stimulusGO:0032101310.015
axonogenesisGO:00074091520.015
golgi vesicle transportGO:004819330.015
negative regulation of signal transductionGO:0009968940.015
atp catabolic processGO:000620040.015
protein targeting to nucleusGO:004474430.015
regulation of dna templated transcription elongationGO:003278430.015
angiogenesisGO:00015251580.015
regulation of cell projection assemblyGO:006049140.015
chordate embryonic developmentGO:00430092710.015
protein complex biogenesisGO:0070271300.014
mitotic sister chromatid segregationGO:000007060.014
cellular component movementGO:00069283350.014
hormone transportGO:000991420.014
regulation of purine nucleotide catabolic processGO:003312120.014
cellular response to chemical stimulusGO:00708871570.014
cell cycle g1 s phase transitionGO:004484310.014
negative regulation of synapse assemblyGO:005196420.014
guanosine containing compound metabolic processGO:190106840.014
segmentationGO:0035282970.014
dna biosynthetic processGO:007189730.014
growthGO:00400071740.014
regulation of developmental growthGO:0048638380.014
symbiosis encompassing mutualism through parasitismGO:004440340.013
regulation of localizationGO:00328791040.013
biosynthetic processGO:00090582940.013
regulation of nucleotide catabolic processGO:003081120.013
nucleotide metabolic processGO:0009117280.013
female gamete generationGO:0007292140.013
cortical actin cytoskeleton organizationGO:003086610.013
positive regulation of gene expressionGO:0010628710.013
regulation of cellular ketone metabolic processGO:001056570.013
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.013
single organism nuclear importGO:190259330.013
protein localization to nucleusGO:003450430.013
adult behaviorGO:003053420.013
mitotic dna damage checkpointGO:004477340.013
cellular ketone metabolic processGO:0042180110.013
regulation of membrane potentialGO:0042391230.013
negative regulation of apoptotic processGO:0043066550.013
peptidyl serine phosphorylationGO:001810510.013
actin polymerization or depolymerizationGO:000815420.013
cellular component disassemblyGO:002241110.012
regulation of nuclear divisionGO:005178390.012
cellular response to organic substanceGO:00713101050.012
regulation of gene expressionGO:00104682650.012
Worm
regenerationGO:0031099910.012
mitotic dna integrity checkpointGO:004477440.012
negative regulation of nitrogen compound metabolic processGO:0051172590.012
regulation of filopodium assemblyGO:005148920.012
wnt signaling pathwayGO:0016055800.012
positive regulation of signalingGO:0023056560.012
apoptotic process involved in developmentGO:190274220.012
regulation of reproductive processGO:200024140.012
organic substance biosynthetic processGO:19015762890.012
protein k48 linked ubiquitinationGO:007093610.012
positive regulation of cell adhesionGO:004578510.012
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
development of primary female sexual characteristicsGO:004654540.011
regulation of locomotionGO:0040012550.011
regulation of phosphorus metabolic processGO:0051174430.011
carbohydrate biosynthetic processGO:001605110.011
maturation of ssu rrnaGO:003049010.011
membrane invaginationGO:001032410.011
regulation of stem cell differentiationGO:200073640.011
regulation of protein modification processGO:0031399290.011
Fly
inflammatory responseGO:000695480.011
regulation of peptidase activityGO:0052547230.011
embryonic organ developmentGO:00485683810.011
establishment of synaptic vesicle localizationGO:009748010.011
golgi organizationGO:000703010.011
macroautophagyGO:001623610.011
g1 s transition of mitotic cell cycleGO:000008210.011
carbohydrate homeostasisGO:003350010.011
protein localization to plasma membraneGO:007265910.011
regulation of hydrolase activityGO:0051336280.011
positive regulation of proteolysisGO:0045862100.011
positive regulation of notch signaling pathwayGO:004574730.011
response to glucocorticoidGO:005138410.011
enzyme linked receptor protein signaling pathwayGO:00071671060.011
regulation of cellular amino acid metabolic processGO:000652100.011
cellular response to dna damage stimulusGO:0006974240.011
Fly
rna catabolic processGO:000640170.011
embryonic limb morphogenesisGO:003032620.011
lateral inhibitionGO:004633110.011
germ cell developmentGO:0007281220.011
regulation of protein metabolic processGO:0051246560.010
Fly
cellular amino acid metabolic processGO:000652070.010
cell substrate adhesionGO:003158940.010
negative regulation of cellular metabolic processGO:0031324770.010
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:004278710.010
cellular response to organic cyclic compoundGO:0071407380.010
negative regulation of defense responseGO:003134820.010
compound eye developmentGO:004874920.010
regulation of alternative mrna splicing via spliceosomeGO:000038110.010
cellular amine metabolic processGO:004410620.010
stem cell proliferationGO:007208940.010
protein import into nucleusGO:000660630.010
mitochondrion organizationGO:000700540.010
positive regulation of macromolecule biosynthetic processGO:0010557590.010

psmd4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
musculoskeletal system diseaseDOID:1700.022
nervous system diseaseDOID:86300.012
sensory system diseaseDOID:005015500.012
muscular diseaseDOID:008000000.010
muscle tissue diseaseDOID:6600.010