Danio rerio

0 known processes

tirap

toll-interleukin 1 receptor (TIR) domain containing adaptor protein

(Aliases: mal)

tirap biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cytokine productionGO:000181730.177
toll like receptor signaling pathwayGO:000222440.104
signal transductionGO:00071654550.103
positive regulation of cytokine productionGO:000181920.096
cellular response to molecule of bacterial originGO:007121930.094
regulation of multicellular organismal processGO:00512392770.091
nitrogen compound metabolic processGO:00068073190.089
response to stressGO:00069502630.082
neuron differentiationGO:00301823530.082
cellular nitrogen compound biosynthetic processGO:00442712180.078
biosynthetic processGO:00090582940.076
positive regulation of transportGO:005105020.075
regulation of response to stimulusGO:00485832690.073
nucleobase containing compound metabolic processGO:00061392740.072
cellular response to biotic stimulusGO:007121630.072
regulation of reactive oxygen species metabolic processGO:200037720.072
larval developmentGO:000216420.070
positive regulation of biological processGO:00485182530.068
nitric oxide biosynthetic processGO:000680920.068
regulation of biosynthetic processGO:00098892500.067
heterocycle metabolic processGO:00464832900.067
response to chemicalGO:00422213200.065
nucleic acid metabolic processGO:00903042440.065
cellular aromatic compound metabolic processGO:00067252950.063
cellular nitrogen compound metabolic processGO:00346412900.063
regulation of rna metabolic processGO:00512522240.062
regulation of metabolic processGO:00192223590.062
regulation of rna biosynthetic processGO:20011412130.062
heterocycle biosynthetic processGO:00181302150.061
response to external stimulusGO:00096052640.061
immune system processGO:00023762410.061
aromatic compound biosynthetic processGO:00194382170.060
neuron developmentGO:00486662620.059
cellular macromolecule biosynthetic processGO:00346452240.059
cellular component movementGO:00069283350.059
regulation of cellular biosynthetic processGO:00313262450.057
organic substance biosynthetic processGO:19015762890.057
macromolecule biosynthetic processGO:00090592270.056
regulation of primary metabolic processGO:00800903110.056
nucleobase containing compound biosynthetic processGO:00346542050.055
cellular macromolecule metabolic processGO:00442603910.054
organic cyclic compound metabolic processGO:19013603010.054
response to organic substanceGO:00100331530.052
cell migrationGO:00164772370.052
regulation of transcription dna templatedGO:00063552130.051
cellular response to lipopolysaccharideGO:007122230.051
regulation of macromolecule biosynthetic processGO:00105562250.050
regulation of macromolecule metabolic processGO:00602553170.050
negative regulation of biological processGO:00485193040.049
regulation of cellular macromolecule biosynthetic processGO:20001122220.049
regulation of dendrite developmentGO:005077330.049
response to hexoseGO:000974630.048
response to drugGO:004249330.048
regulation of gene expressionGO:00104682650.048
gene expressionGO:00104672520.048
positive regulation of immune effector processGO:000269930.048
production of molecular mediator of immune responseGO:000244020.047
agingGO:000756820.047
response to external biotic stimulusGO:0043207970.046
type i interferon productionGO:003260620.045
regulation of multicellular organismal developmentGO:20000262230.044
positive regulation of secretion by cellGO:190353210.044
defense response to other organismGO:0098542330.044
regulation of biological qualityGO:00650082630.044
regulation of protein modification by small protein conjugation or removalGO:190332030.043
regulation of nucleobase containing compound metabolic processGO:00192192500.042
regulation of establishment of protein localizationGO:007020140.042
rna biosynthetic processGO:00327741810.042
positive regulation of i kappab kinase nf kappab signalingGO:004312330.042
programmed cell deathGO:00125011190.041
rna metabolic processGO:00160702190.041
cellular biosynthetic processGO:00442492860.041
response to bacteriumGO:0009617580.040
regulation of nucleic acid templated transcriptionGO:19035062130.039
regulation of cellular metabolic processGO:00313233200.039
negative regulation of protein phosphorylationGO:000193340.039
cell part morphogenesisGO:00329902460.039
regulation of protein transportGO:005122330.038
stem cell maintenanceGO:001982740.038
positive regulation of cellular component biogenesisGO:004408930.038
regulation of immune system processGO:0002682340.038
negative regulation of cytokine productionGO:000181810.038
regulation of nitrogen compound metabolic processGO:00511712510.037
symbiosis encompassing mutualism through parasitismGO:004440340.037
cell projection morphogenesisGO:00488582440.037
response to carbohydrateGO:000974330.037
nucleic acid templated transcriptionGO:00976591810.037
regulation of response to stressGO:0080134360.036
transportGO:00068102200.036
protein metabolic processGO:00195381830.035
cellular ketone metabolic processGO:0042180110.035
regulation of innate immune responseGO:0045088110.034
locomotionGO:00400113130.034
i kappab kinase nf kappab signalingGO:000724940.034
amine metabolic processGO:000930820.033
regulation of signalingGO:00230512350.033
positive regulation of secretionGO:005104710.032
regulation of cellular amine metabolic processGO:003323800.032
maintenance of locationGO:005123540.031
organic cyclic compound biosynthetic processGO:19013622230.031
positive regulation of cellular processGO:00485222010.031
neuron projection developmentGO:00311751800.031
leukocyte proliferationGO:007066110.031
single organism transportGO:00447652060.031
intracellular signal transductionGO:0035556850.030
cellular response to chemical stimulusGO:00708871570.030
regulation of cellular amino acid metabolic processGO:000652100.030
multicellular organism growthGO:003526440.030
positive regulation of catabolic processGO:000989640.030
fertilizationGO:000956630.030
response to biotic stimulusGO:0009607970.030
regulation of cellular ketone metabolic processGO:001056570.030
negative regulation of cellular processGO:00485232830.030
regulation of bindingGO:005109830.029
negative regulation of protein kinase activityGO:000646940.029
reactive nitrogen species metabolic processGO:200105700.029
regulation of synapse organizationGO:005080730.029
regulation of protein metabolic processGO:0051246560.029
b cell activationGO:004211320.029
chordate embryonic developmentGO:00430092710.029
guanosine containing compound metabolic processGO:190106840.029
nucleocytoplasmic transportGO:000691340.028
response to other organismGO:0051707970.028
vasculature developmentGO:00019442780.028
cellular protein catabolic processGO:004425740.028
generation of neuronsGO:00486993850.028
organonitrogen compound metabolic processGO:1901564740.028
cytokinesisGO:000091030.027
regulation of protein catabolic processGO:004217610.027
positive regulation of cell cycleGO:004578730.027
guanosine containing compound catabolic processGO:190106920.027
brain developmentGO:00074202930.027
lymphocyte proliferationGO:004665110.027
single fertilizationGO:000733830.027
positive regulation of biosynthetic processGO:0009891680.027
positive regulation of cellular catabolic processGO:003133130.027
cellular amine metabolic processGO:004410620.027
interspecies interaction between organismsGO:004441940.027
proteolysis involved in cellular protein catabolic processGO:005160330.026
regulation of reproductive processGO:200024140.026
positive regulation of metabolic processGO:00098931080.026
system processGO:00030081850.026
regulation of production of molecular mediator of immune responseGO:000270010.026
single organism metabolic processGO:00447102170.026
regulation of synapse assemblyGO:005196330.026
regulation of protein ubiquitinationGO:003139630.026
regulation of signal transductionGO:00099662250.026
oxoacid metabolic processGO:0043436310.026
proteasomal protein catabolic processGO:001049820.025
response to glucoseGO:000974930.025
antimicrobial humoral responseGO:001973020.025
protein secretionGO:000930610.025
nuclear transportGO:005116940.025
head developmentGO:00603223030.025
gtp metabolic processGO:004603940.025
embryonic organ developmentGO:00485683810.024
muscle structure developmentGO:00610611960.024
positive regulation of nitrogen compound metabolic processGO:0051173690.024
cellular amino acid metabolic processGO:000652070.024
cell morphogenesis involved in neuron differentiationGO:00486671630.024
lipid storageGO:001991510.024
positive regulation of immune system processGO:0002684170.024
regulation of multicellular organism growthGO:004001440.024
regulation of cell activationGO:005086510.024
negative regulation of kinase activityGO:003367340.024
cellular component morphogenesisGO:00329893360.024
response to monosaccharideGO:003428430.024
somite developmentGO:0061053960.024
regulation of cell communicationGO:00106462320.024
regulation of cytokine biosynthetic processGO:004203510.024
modification dependent protein catabolic processGO:001994130.024
synaptic growth at neuromuscular junctionGO:005112420.024
growthGO:00400071740.024
exocytosisGO:000688710.023
activation of immune responseGO:000225390.023
regulation of i kappab kinase nf kappab signalingGO:004312240.023
positive regulation of signalingGO:0023056560.023
cellular response to external stimulusGO:007149620.023
negative regulation of multicellular organismal processGO:0051241690.023
neuron projection morphogenesisGO:00488121610.023
establishment of protein localization to organelleGO:007259440.023
cellular response to organic substanceGO:00713101050.023
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.023
organic acid metabolic processGO:0006082310.023
regulation of inflammatory responseGO:005072720.022
reactive oxygen species metabolic processGO:007259360.022
extrinsic apoptotic signaling pathwayGO:009719130.022
stem cell proliferationGO:007208940.022
small molecule metabolic processGO:0044281770.022
positive regulation of cellular biosynthetic processGO:0031328680.022
transcription from rna polymerase ii promoterGO:0006366800.022
embryonic organ morphogenesisGO:00485622740.022
cell projection organizationGO:00300302840.022
tube morphogenesisGO:00352393490.022
cell morphogenesis involved in differentiationGO:00009041950.022
blood vessel morphogenesisGO:00485142160.022
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.022
protein localization to nucleusGO:003450430.022
regulation of apoptotic processGO:0042981980.022
ubiquitin dependent protein catabolic processGO:000651130.022
positive regulation of cellular amine metabolic processGO:003324000.021
phagocytosisGO:000690930.021
morphogenesis of an epitheliumGO:00020093330.021
regulation of nervous system developmentGO:0051960900.021
regulation of protein bindingGO:004339330.021
transcription dna templatedGO:00063511810.021
regulation of developmental processGO:00507932470.021
nitric oxide metabolic processGO:004620920.021
protein acetylationGO:000647320.021
gtp catabolic processGO:000618420.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
protein modification processGO:00362111000.021
positive regulation of cytokine biosynthetic processGO:004210810.021
cell surface receptor signaling pathwayGO:00071663250.021
defense responseGO:0006952470.021
blood vessel developmentGO:00015682460.021
regionalizationGO:00030022740.021
cell morphogenesisGO:00009022890.020
modification dependent macromolecule catabolic processGO:004363230.020
positive regulation of macromolecule biosynthetic processGO:0010557590.020
autophagyGO:000691440.020
regulation of dendrite morphogenesisGO:004881430.020
positive regulation of response to stimulusGO:0048584800.020
multi organism processGO:00517041340.020
response to molecule of bacterial originGO:0002237140.020
heart developmentGO:00075073130.020
establishment of localizationGO:00512342440.020
activation of innate immune responseGO:000221860.020
glucose homeostasisGO:004259310.020
regulation of cell developmentGO:00602841000.020
single organism nuclear importGO:190259330.020
regulation of cell differentiationGO:00455951420.020
carboxylic acid metabolic processGO:0019752220.020
immune system developmentGO:00025201910.019
cell deathGO:00082191210.019
anterior posterior pattern specificationGO:00099521520.019
regulation of peptidyl tyrosine phosphorylationGO:005073010.019
regulation of localizationGO:00328791040.019
regulation of interferon beta productionGO:003264810.019
apoptotic processGO:00069151160.019
cell motilityGO:00488702440.019
regulation of synaptic growth at neuromuscular junctionGO:000858210.019
regulation of defense responseGO:0031347140.019
neurotransmitter transportGO:000683620.019
somatic muscle developmentGO:000752540.019
meiotic cell cycle processGO:190304630.019
central nervous system developmentGO:00074173870.019
interferon beta productionGO:003260810.019
protein targeting to nucleusGO:004474430.019
lipid catabolic processGO:001604240.018
carbohydrate homeostasisGO:003350010.018
regulation of purine nucleotide catabolic processGO:003312120.018
adult behaviorGO:003053420.018
hemopoiesisGO:00300971830.018
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.018
rna localizationGO:000640340.018
purine ribonucleoside monophosphate catabolic processGO:000916940.018
regulation of cytoplasmic transportGO:190364940.018
b cell mediated immunityGO:001972430.018
homeostatic processGO:00425921420.018
regulation of epithelial cell proliferationGO:005067830.018
mononuclear cell proliferationGO:003294310.018
regulation of nucleoside metabolic processGO:000911820.018
adherens junction organizationGO:003433240.018
somitogenesisGO:0001756870.018
positive regulation of myeloid cell differentiationGO:004563920.017
internal protein amino acid acetylationGO:000647520.017
single organism membrane fusionGO:004480120.017
germ line stem cell maintenanceGO:003071820.017
regulation of protein localization to nucleusGO:190018020.017
regulation of neuron differentiationGO:0045664560.017
protein import into nucleusGO:000660630.017
cellular carbohydrate metabolic processGO:004426240.017
hematopoietic or lymphoid organ developmentGO:00485341910.017
ovulation cycleGO:004269820.017
stem cell divisionGO:001714510.017
regulation of cell shapeGO:000836010.017
positive regulation of cellular metabolic processGO:0031325940.017
response to woundingGO:00096111160.017
regulation of molecular functionGO:0065009700.017
positive regulation of macromolecule metabolic processGO:0010604930.017
organelle organizationGO:00069962270.017
regulation of nucleocytoplasmic transportGO:004682220.017
peptidyl lysine acetylationGO:001839420.016
positive regulation of molecular functionGO:0044093330.016
regulation of blood pressureGO:000821710.016
striated muscle cell differentiationGO:00511461290.016
regulation of cellular protein catabolic processGO:190336210.016
cytoskeleton dependent cytokinesisGO:006164030.016
protein importGO:001703830.016
immunoglobulin mediated immune responseGO:001606430.016
determination of left right symmetryGO:00073681790.016
atp catabolic processGO:000620040.016
regulation of autophagyGO:001050630.016
localization of cellGO:00516742440.016
nuclear importGO:005117030.016
hormone transportGO:000991420.016
female sex differentiationGO:004666040.016
positive regulation of immune responseGO:0050778110.016
heart morphogenesisGO:00030071560.016
amino acid transportGO:000686520.016
positive regulation of cytoskeleton organizationGO:005149530.016
cytokine metabolic processGO:004210710.016
regulation of tube sizeGO:003515020.016
myeloid cell differentiationGO:0030099860.016
camera type eye morphogenesisGO:00485931080.015
organelle fusionGO:004828430.015
regulation of intracellular protein transportGO:003315730.015
regulation of neurotransmitter transportGO:005158810.015
digestive system developmentGO:00551232890.015
compound eye developmentGO:004874920.015
ribonucleoside monophosphate catabolic processGO:000915840.015
meiotic nuclear divisionGO:000712640.015
mitochondrion organizationGO:000700540.015
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.015
regulation of response to biotic stimulusGO:000283120.015
regulation of metal ion transportGO:001095940.015
macromolecule modificationGO:00434121110.015
cellular response to starvationGO:000926710.015
axonogenesisGO:00074091520.015
regulation of type i interferon productionGO:003247920.015
axon developmentGO:00615641660.015
immune effector processGO:0002252230.015
cellular response to radiationGO:007147840.015
immune response regulating signaling pathwayGO:000276450.015
peptide transportGO:001583310.015
regulation of programmed cell deathGO:00430671010.015
determination of bilateral symmetryGO:00098552040.015
negative regulation of protein serine threonine kinase activityGO:007190120.015
phosphate containing compound metabolic processGO:00067961080.015
regulation of blood vessel sizeGO:005088020.015
female gonad developmentGO:000858540.015
regulation of protein complex assemblyGO:004325430.015
positive regulation of gene expressionGO:0010628710.015
response to endogenous stimulusGO:0009719830.015
spermatid developmentGO:000728620.015
regulation of neurogenesisGO:0050767870.014
cellular component biogenesisGO:00440851780.014
eye developmentGO:00016542770.014
cellular response to endogenous stimulusGO:0071495680.014
spermatid differentiationGO:004851520.014
regulation of anatomical structure morphogenesisGO:00226031300.014
neuroblast proliferationGO:000740520.014
tissue remodelingGO:004877140.014
developmental growthGO:00485891660.014
negative regulation of chromosome organizationGO:200125110.014
cytokinetic processGO:003250620.014
regulation of cell deathGO:00109411030.014
purine nucleoside monophosphate catabolic processGO:000912840.014
neurotransmitter secretionGO:000726920.014
protein acylationGO:004354330.014
muscle organ developmentGO:00075171010.014
eye morphogenesisGO:00485921440.014
cell substrate adhesionGO:003158940.014
response to oxygen containing compoundGO:1901700550.014
positive regulation of epithelial cell differentiationGO:003085820.014
regulation of stem cell proliferationGO:007209120.014
cytokine production involved in immune responseGO:000236710.014
positive regulation of lymphocyte mediated immunityGO:000270810.014
positive regulation of multicellular organismal processGO:0051240520.014
positive regulation of translationGO:004572710.014
striated muscle cell developmentGO:00550021080.014
positive regulation of rna metabolic processGO:0051254590.014
regulation of nucleotide catabolic processGO:003081120.014
internal peptidyl lysine acetylationGO:001839320.014
phosphorus metabolic processGO:00067931090.014
positive regulation of cell activationGO:005086710.013
regulation of neurotransmitter secretionGO:004692810.013
sensory organ morphogenesisGO:00905962000.013
endosomal transportGO:001619720.013
cellular protein modification processGO:00064641000.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.013
positive regulation of cell killingGO:003134320.013
neuron neuron synaptic transmissionGO:000727010.013
sensory organ developmentGO:00074233930.013
regulation of gtpase activityGO:004308720.013
positive regulation of jnk cascadeGO:004633030.013
positive regulation of defense responseGO:003134990.013
negative regulation of secretionGO:005104820.013
striated muscle tissue developmentGO:00147061100.013
positive regulation of stress activated mapk cascadeGO:003287430.013
wnt signaling pathwayGO:0016055800.013
regulation of protein import into nucleusGO:004230620.013
development of primary female sexual characteristicsGO:004654540.013
positive regulation of map kinase activityGO:004340630.013
camera type eye developmentGO:00430102220.013
endocrine processGO:005088620.013
positive regulation of purine nucleotide catabolic processGO:003312310.013
protein heterooligomerizationGO:005129110.013
protein polymerizationGO:005125840.013
regulation of gtp catabolic processGO:003312420.013
membrane invaginationGO:001032410.013
regulation of protein targetingGO:190353320.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
regulation of transcription from rna polymerase ii promoterGO:00063571140.013
deathGO:00162651210.013
hormone secretionGO:004687920.013
myeloid cell homeostasisGO:0002262560.013
cellular amide metabolic processGO:004360340.013
phosphorylationGO:0016310690.013
positive regulation of innate immune responseGO:004508980.013
single organism localizationGO:19025782250.013
angiogenesisGO:00015251580.013
specification of symmetryGO:00097992040.013
innate immune response activating signal transductionGO:000275850.013
inositol lipid mediated signalingGO:004801720.013
dorsal ventral pattern formationGO:00099531250.013
negative regulation of mapk cascadeGO:004340940.013
negative regulation of defense responseGO:003134820.013
phototransductionGO:000760220.013
post embryonic organ developmentGO:004856940.013
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.013
small molecule catabolic processGO:004428230.013
regulation of stem cell differentiationGO:200073640.013
phagocytosis engulfmentGO:000691110.012
carbohydrate biosynthetic processGO:001605110.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
negative regulation of catabolic processGO:000989530.012
positive regulation of dna metabolic processGO:005105410.012
response to corticosteroidGO:003196010.012
cellular protein metabolic processGO:00442671290.012
cellular component disassemblyGO:002241110.012
embryo development ending in birth or egg hatchingGO:00097922710.012
membrane fusionGO:006102520.012
cellular response to nutrient levelsGO:003166920.012
circulatory system processGO:0003013870.012
negative regulation of protein transportGO:005122430.012
response to uvGO:000941130.012
translational initiationGO:000641330.012
reactive oxygen species biosynthetic processGO:190340910.012
ameboidal type cell migrationGO:00016671430.012
protein dephosphorylationGO:000647030.012
cognitionGO:005089010.012
regulation of hormone secretionGO:004688320.012
microtubule organizing center organizationGO:003102310.012
protein homooligomerizationGO:005126030.012
single organism organelle organizationGO:19025891990.012
cell cycle g1 s phase transitionGO:004484310.012
regulation of systemic arterial blood pressureGO:000307310.012
negative regulation of map kinase activityGO:004340720.012
determination of heart left right asymmetryGO:00613711170.012
positive regulation of production of molecular mediator of immune responseGO:000270210.012
positive regulation of type i interferon productionGO:003248110.012
positive regulation of nucleoside metabolic processGO:004597910.012
negative regulation of multi organism processGO:004390130.012
positive regulation of cell communicationGO:0010647560.012
transmembrane transportGO:00550851200.012
actin polymerization or depolymerizationGO:000815420.012
cellular localizationGO:0051641970.012
regulation of jak stat cascadeGO:004642530.012
positive regulation of multi organism processGO:004390230.012
lipid homeostasisGO:005508830.012
taxisGO:00423301090.012
positive regulation of protein complex assemblyGO:003133420.012
regulation of wound healingGO:006104120.012
nuclear migrationGO:000709730.012
actin filament polymerizationGO:003004120.012
regulation of synaptic plasticityGO:004816710.012
negative regulation of cytoplasmic transportGO:190365020.012
cellular response to extracellular stimulusGO:003166820.011
innate immune responseGO:0045087130.011
response to abiotic stimulusGO:00096281220.011
chemotaxisGO:00069351040.011
developmental programmed cell deathGO:001062340.011
negative regulation of dna metabolic processGO:005105340.011
negative regulation of reproductive processGO:200024230.011
negative regulation of cellular catabolic processGO:003133030.011
secondary metabolic processGO:001974830.011
positive regulation of cell divisionGO:005178120.011
cellular response to stressGO:0033554620.011
positive regulation of synapse assemblyGO:005196510.011
positive regulation of signal transductionGO:0009967560.011
nuclear exportGO:005116810.011
p38mapk cascadeGO:003806610.011
epithelial cell differentiationGO:00308551160.011
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.011
b cell differentiationGO:003018310.011
regulation of neuron projection developmentGO:0010975400.011
regulation of circadian rhythmGO:004275240.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
positive regulation of chromosome organizationGO:200125210.011
positive regulation of leukocyte migrationGO:000268720.011
positive regulation of leukocyte differentiationGO:190210710.011

tirap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
musculoskeletal system diseaseDOID:1700.027
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.017
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.016
immune system diseaseDOID:291400.015
muscular diseaseDOID:008000000.014
muscle tissue diseaseDOID:6600.014
eye and adnexa diseaseDOID:149200.012
eye diseaseDOID:561400.012
sensory system diseaseDOID:005015500.012