Danio rerio

39 known processes

plekhg5a

pleckstrin homology domain containing, family G (with RhoGef domain) member 5a

(Aliases: si:ch211-15p9.7,plekhg5)

plekhg5a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vasculature developmentGO:00019442780.578
blood vessel morphogenesisGO:00485142160.438
angiogenesisGO:00015251580.333
cell migrationGO:00164772370.295
localization of cellGO:00516742440.264
sprouting angiogenesisGO:0002040530.242
regulation of cellular metabolic processGO:00313233200.230
digestive tract developmentGO:00485652650.199
extrinsic apoptotic signaling pathwayGO:009719130.172
signal transductionGO:00071654550.172
negative regulation of biological processGO:00485193040.170
stem cell proliferationGO:007208940.165
cellular component movementGO:00069283350.162
tube morphogenesisGO:00352393490.158
locomotionGO:00400113130.132
nucleic acid metabolic processGO:00903042440.129
growthGO:00400071740.123
regulation of developmental processGO:00507932470.122
cell surface receptor signaling pathwayGO:00071663250.116
nitrogen compound metabolic processGO:00068073190.115
regulation of multicellular organismal developmentGO:20000262230.115
central nervous system developmentGO:00074173870.114
regulation of synapse organizationGO:005080730.114
gastrulationGO:00073692080.113
determination of bilateral symmetryGO:00098552040.107
phagocytosisGO:000690930.106
neuron developmentGO:00486662620.105
meiotic nuclear divisionGO:000712640.105
single organism localizationGO:19025782250.105
establishment of localizationGO:00512342440.102
peptidyl serine phosphorylationGO:001810510.100
regulation of biological qualityGO:00650082630.098
positive regulation of biological processGO:00485182530.097
cell motilityGO:00488702440.095
cell morphogenesis involved in differentiationGO:00009041950.093
heterocycle metabolic processGO:00464832900.092
ameboidal type cell migrationGO:00016671430.090
digestive system developmentGO:00551232890.088
cell substrate adhesionGO:003158940.087
blood vessel developmentGO:00015682460.087
rna metabolic processGO:00160702190.086
embryonic organ developmentGO:00485683810.085
heart morphogenesisGO:00030071560.083
regulation of cell communicationGO:00106462320.080
cellular component biogenesisGO:00440851780.077
meiotic cell cycle processGO:190304630.077
heart developmentGO:00075073130.077
apoptotic processGO:00069151160.077
developmental growthGO:00485891660.076
positive regulation of transportGO:005105020.076
regulation of response to stimulusGO:00485832690.076
transcription dna templatedGO:00063511810.076
cell morphogenesis involved in neuron differentiationGO:00486671630.075
cell projection morphogenesisGO:00488582440.075
regulation of extrinsic apoptotic signaling pathwayGO:200123630.075
morphogenesis of an epitheliumGO:00020093330.073
immune system developmentGO:00025201910.073
hematopoietic or lymphoid organ developmentGO:00485341910.070
generation of neuronsGO:00486993850.068
cell morphogenesisGO:00009022890.068
cellular amine metabolic processGO:004410620.067
regulation of multicellular organismal processGO:00512392770.066
chemotaxisGO:00069351040.065
regulation of nucleobase containing compound metabolic processGO:00192192500.064
cellular macromolecule metabolic processGO:00442603910.064
regulation of rna biosynthetic processGO:20011412130.064
larval developmentGO:000216420.063
immune system processGO:00023762410.063
neuron projection developmentGO:00311751800.063
regulation of apoptotic processGO:0042981980.063
nucleobase containing compound metabolic processGO:00061392740.062
nuclear transportGO:005116940.061
negative regulation of protein phosphorylationGO:000193340.061
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.061
negative regulation of response to stimulusGO:00485851040.061
regulation of dna replicationGO:000627530.061
organic cyclic compound metabolic processGO:19013603010.060
peptidyl serine modificationGO:001820920.060
regulation of cellular component organizationGO:0051128860.060
heterocycle biosynthetic processGO:00181302150.059
positive regulation of catabolic processGO:000989640.059
response to chemicalGO:00422213200.059
hypothalamus cell differentiationGO:002197940.058
neuron projection morphogenesisGO:00488121610.058
germ line stem cell maintenanceGO:003071820.057
agingGO:000756820.057
regulation of primary metabolic processGO:00800903110.057
response to external stimulusGO:00096052640.056
positive regulation of cellular processGO:00485222010.056
regulation of macromolecule metabolic processGO:00602553170.056
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.055
cell part morphogenesisGO:00329902460.055
single organism nuclear importGO:190259330.055
positive regulation of nitrogen compound metabolic processGO:0051173690.055
macromolecule biosynthetic processGO:00090592270.054
skeletal system developmentGO:00015011810.054
specification of symmetryGO:00097992040.054
negative regulation of cellular processGO:00485232830.053
rna biosynthetic processGO:00327741810.053
axon developmentGO:00615641660.053
organelle organizationGO:00069962270.052
establishment of protein localization to organelleGO:007259440.052
gland developmentGO:00487321430.052
positive regulation of cellular catabolic processGO:003133130.052
positive regulation of cell adhesionGO:004578510.052
protein import into nucleusGO:000660630.051
cell matrix adhesionGO:000716040.050
eye developmentGO:00016542770.050
regulation of cell shapeGO:000836010.049
response to stressGO:00069502630.049
transcription from rna polymerase ii promoterGO:0006366800.048
cellular nitrogen compound metabolic processGO:00346412900.048
cell deathGO:00082191210.048
hemopoiesisGO:00300971830.047
single organism transportGO:00447652060.047
regulation of establishment of protein localizationGO:007020140.047
regulation of cellular biosynthetic processGO:00313262450.047
regulation of transcription dna templatedGO:00063552130.047
chordate embryonic developmentGO:00430092710.047
deathGO:00162651210.046
cell projection organizationGO:00300302840.045
transportGO:00068102200.045
regulation of metabolic processGO:00192223590.044
muscle structure developmentGO:00610611960.044
enzyme linked receptor protein signaling pathwayGO:00071671060.044
gene expressionGO:00104672520.044
protein localization to nucleusGO:003450430.044
cellular nitrogen compound biosynthetic processGO:00442712180.043
regulation of cell differentiationGO:00455951420.043
regulation of cellular amino acid metabolic processGO:000652100.043
regulation of protein import into nucleusGO:004230620.042
regulation of signalingGO:00230512350.042
neuron differentiationGO:00301823530.042
response to hexoseGO:000974630.042
connective tissue developmentGO:0061448990.042
erk1 and erk2 cascadeGO:007037140.042
digestive tract morphogenesisGO:00485462310.042
cellular aromatic compound metabolic processGO:00067252950.041
positive regulation of cellular component biogenesisGO:004408930.041
signal transduction in absence of ligandGO:003803410.041
regulation of anatomical structure morphogenesisGO:00226031300.041
system processGO:00030081850.041
regionalizationGO:00030022740.041
sensory organ developmentGO:00074233930.040
axonogenesisGO:00074091520.040
synaptic vesicle transportGO:004848910.040
regulation of cellular macromolecule biosynthetic processGO:20001122220.040
cellular component assemblyGO:00226071700.039
regulation of protein transportGO:005122330.039
regulation of programmed cell deathGO:00430671010.039
regulation of nitrogen compound metabolic processGO:00511712510.039
regulation of cell deathGO:00109411030.039
negative regulation of protein complex assemblyGO:003133310.039
regulation of protein localization to nucleusGO:190018020.038
negative regulation of signalingGO:0023057960.038
establishment of localization in cellGO:0051649770.038
phosphate containing compound metabolic processGO:00067961080.038
regulation of cell morphogenesisGO:0022604420.038
regulation of protein targetingGO:190353320.038
biosynthetic processGO:00090582940.038
organic substance biosynthetic processGO:19015762890.037
nucleocytoplasmic transportGO:000691340.037
locomotor rhythmGO:004547530.037
striated muscle tissue developmentGO:00147061100.037
synaptic growth at neuromuscular junctionGO:005112420.037
head developmentGO:00603223030.037
regulation of locomotionGO:0040012550.036
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.036
maintenance of locationGO:005123540.036
amine metabolic processGO:000930820.036
cytoskeleton organizationGO:0007010960.036
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.035
regulation of synaptic growth at neuromuscular junctionGO:000858210.035
positive regulation of apoptotic signaling pathwayGO:200123510.035
ubiquitin dependent protein catabolic processGO:000651130.035
adult behaviorGO:003053420.035
brain developmentGO:00074202930.035
regulation of cell substrate adhesionGO:001081010.035
regulation of signal transductionGO:00099662250.035
regulation of neural precursor cell proliferationGO:200017730.035
cartilage developmentGO:0051216960.034
phagocytosis engulfmentGO:000691110.034
muscle organ developmentGO:00075171010.034
aromatic compound biosynthetic processGO:00194382170.034
muscle tissue developmentGO:00605371100.034
membrane lipid biosynthetic processGO:004646720.034
cellular amino acid metabolic processGO:000652070.034
neurological system processGO:0050877620.034
cellular macromolecule biosynthetic processGO:00346452240.033
nucleic acid templated transcriptionGO:00976591810.033
stem cell divisionGO:001714510.033
sensory organ morphogenesisGO:00905962000.033
negative regulation of metabolic processGO:0009892860.033
tissue remodelingGO:004877140.032
positive regulation of blood circulationGO:190352420.032
regulation of bindingGO:005109830.032
single organism metabolic processGO:00447102170.032
myeloid cell homeostasisGO:0002262560.032
cortical cytoskeleton organizationGO:003086510.032
programmed cell deathGO:00125011190.031
modification dependent protein catabolic processGO:001994130.031
regulation of cellular amine metabolic processGO:003323800.031
energy reserve metabolic processGO:000611220.031
cellular component morphogenesisGO:00329893360.031
multicellular organism growthGO:003526440.031
myeloid cell differentiationGO:0030099860.031
negative regulation of developmental processGO:0051093650.031
erythrocyte homeostasisGO:0034101550.031
regulation of nucleocytoplasmic transportGO:004682220.031
neuroblast proliferationGO:000740520.031
regulation of jak stat cascadeGO:004642530.030
cellular response to chemical stimulusGO:00708871570.030
regulation of nucleic acid templated transcriptionGO:19035062130.030
organic cyclic compound biosynthetic processGO:19013622230.030
lipid storageGO:001991510.030
skeletal muscle organ developmentGO:0060538780.030
positive regulation of cellular amino acid metabolic processGO:004576400.030
regulation of biosynthetic processGO:00098892500.030
axon guidanceGO:0007411860.030
regulation of cytoplasmic transportGO:190364940.030
organelle assemblyGO:00709251100.030
regulation of metal ion transportGO:001095940.030
actin filament based processGO:0030029640.030
nucleobase containing compound biosynthetic processGO:00346542050.029
regulation of reactive oxygen species metabolic processGO:200037720.029
response to drugGO:004249330.029
cell growthGO:0016049570.029
establishment of synaptic vesicle localizationGO:009748010.029
regulation of autophagyGO:001050630.029
negative regulation of signal transductionGO:0009968940.029
small molecule metabolic processGO:0044281770.029
positive regulation of cell cycleGO:004578730.029
regulation of rna metabolic processGO:00512522240.029
regulation of macromolecule biosynthetic processGO:00105562250.028
gtp catabolic processGO:000618420.028
taxisGO:00423301090.028
inorganic ion transmembrane transportGO:0098660570.028
mesoderm developmentGO:0007498880.028
positive regulation of cellular biosynthetic processGO:0031328680.028
synaptic vesicle localizationGO:009747910.028
regulation of cell matrix adhesionGO:000195210.028
sensory perception of chemical stimulusGO:000760630.028
regulation of stem cell proliferationGO:007209120.028
regulation of protein catabolic processGO:004217610.028
positive regulation of cell substrate adhesionGO:001081110.027
response to woundingGO:00096111160.027
cell cycleGO:0007049930.027
positive regulation of protein kinase b signalingGO:005189710.027
regulation of peptidyl tyrosine phosphorylationGO:005073010.027
embryonic hemopoiesisGO:0035162530.027
regulation of intracellular protein transportGO:003315730.027
ion transmembrane transportGO:0034220910.027
negative regulation of cytoplasmic transportGO:190365020.026
g1 s transition of mitotic cell cycleGO:000008210.026
proteolysis involved in cellular protein catabolic processGO:005160330.026
regulation of growthGO:0040008420.026
pericardium developmentGO:006003910.026
organic acid metabolic processGO:0006082310.026
regulation of cell cycleGO:0051726520.026
cellular protein catabolic processGO:004425740.026
single organism organelle organizationGO:19025891990.026
regulation of dendrite developmentGO:005077330.026
cellular biosynthetic processGO:00442492860.026
behaviorGO:0007610740.026
cell migration involved in gastrulationGO:0042074790.026
response to carbohydrateGO:000974330.026
regulation of endothelial cell proliferationGO:000193610.025
mitotic cell cycle processGO:1903047480.025
adherens junction organizationGO:003433240.025
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.025
lymph vessel developmentGO:0001945270.025
positive regulation of response to stimulusGO:0048584800.025
positive regulation of metabolic processGO:00098931080.025
macromolecular complex subunit organizationGO:0043933740.024
mononuclear cell proliferationGO:003294310.024
negative regulation of apoptotic processGO:0043066550.024
positive regulation of immune effector processGO:000269930.024
positive regulation of developmental processGO:0051094500.024
positive regulation of cellular amine metabolic processGO:003324000.024
modification dependent macromolecule catabolic processGO:004363230.024
response to glucoseGO:000974930.024
intracellular signal transductionGO:0035556850.024
protein targeting to nucleusGO:004474430.024
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.024
regulation of cytokine productionGO:000181730.024
regulation of cell migration involved in sprouting angiogenesisGO:009004930.024
synaptic vesicle recyclingGO:003646510.023
carboxylic acid metabolic processGO:0019752220.023
regulation of protein complex assemblyGO:004325430.023
regulation of tube sizeGO:003515020.023
regulation of dna templated transcription in response to stressGO:004362000.023
inorganic cation transmembrane transportGO:0098662500.023
response to abiotic stimulusGO:00096281220.023
inositol lipid mediated signalingGO:004801720.023
convergent extensionGO:00600261180.023
negative regulation of macromolecule metabolic processGO:0010605760.023
cellular response to external stimulusGO:007149620.023
regulation of multicellular organism growthGO:004001440.023
regulation of neurogenesisGO:0050767870.023
regulation of cellular ketone metabolic processGO:001056570.023
mitotic cell cycleGO:0000278640.023
microtubule based processGO:0007017600.022
regulation of erk1 and erk2 cascadeGO:007037240.022
positive regulation of signal transductionGO:0009967560.022
positive regulation of cellular metabolic processGO:0031325940.022
cortical actin cytoskeleton organizationGO:003086610.022
regulation of ion transmembrane transporter activityGO:003241220.022
ventricular cardiac muscle tissue morphogenesisGO:005501020.022
oocyte maturationGO:000155640.022
oxoacid metabolic processGO:0043436310.022
nuclear importGO:005117030.022
cell cycle g1 s phase transitionGO:004484310.022
negative regulation of synapse assemblyGO:005196420.022
positive regulation of endothelial cell proliferationGO:000193810.022
cell proliferationGO:0008283800.022
carbohydrate homeostasisGO:003350010.022
exocytosisGO:000688710.022
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.022
autophagyGO:000691440.022
nephron tubule morphogenesisGO:007207810.022
protein importGO:001703830.021
regulation of epithelial cell proliferationGO:005067830.021
guanosine containing compound metabolic processGO:190106840.021
cytokinesisGO:000091030.021
regulation of localizationGO:00328791040.021
cellular component disassemblyGO:002241110.021
guanosine containing compound catabolic processGO:190106920.021
lateral inhibitionGO:004633110.021
regulation of systemic arterial blood pressureGO:000307310.021
positive regulation of rna metabolic processGO:0051254590.021
regulation of catalytic activityGO:0050790550.021
macromolecule modificationGO:00434121110.021
negative regulation of ras protein signal transductionGO:004658010.021
embryonic organ morphogenesisGO:00485622740.021
multi organism processGO:00517041340.021
membrane invaginationGO:001032410.021
negative regulation of protein kinase activityGO:000646940.021
embryo development ending in birth or egg hatchingGO:00097922710.020
gtp metabolic processGO:004603940.020
actin cytoskeleton organizationGO:0030036630.020
tissue migrationGO:0090130370.020
synaptic vesicle endocytosisGO:004848810.020
protein localization to plasma membraneGO:007265910.020
negative regulation of kinase activityGO:003367340.020
positive regulation of map kinase activityGO:004340630.020
regulation of cell developmentGO:00602841000.020
regulation of erythrocyte differentiationGO:004564620.020
proteasomal protein catabolic processGO:001049820.020
regulation of reproductive processGO:200024140.020
centrosome organizationGO:005129710.020
negative regulation of cell communicationGO:0010648960.020
protein modification processGO:00362111000.020
negative regulation of cell deathGO:0060548600.020
regulation of cell activationGO:005086510.020
negative regulation of multicellular organismal processGO:0051241690.020
phosphorylationGO:0016310690.019
transmembrane transportGO:00550851200.019
protein metabolic processGO:00195381830.019
sphingolipid biosynthetic processGO:003014820.019
heart contractionGO:0060047710.019
cardiac muscle tissue developmentGO:0048738480.019
cellular response to nutrient levelsGO:003166920.019
primitive hemopoiesisGO:0060215270.019
endocrine processGO:005088620.019
cardiac atrium developmentGO:000323040.019
regulation of peptidase activityGO:0052547230.019
response to monosaccharideGO:003428430.019
regulation of transcription from rna polymerase ii promoterGO:00063571140.019
cation transportGO:0006812810.019
cognitionGO:005089010.018
regulation of bmp signaling pathwayGO:0030510390.018
lymphangiogenesisGO:0001946250.018
kidney developmentGO:0001822920.018
stem cell maintenanceGO:001982740.018
negative regulation of gene expressionGO:0010629650.018
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.018
establishment of organelle localizationGO:0051656450.018
homeostatic processGO:00425921420.018
cellular response to hypoxiaGO:007145610.018
circulatory system processGO:0003013870.018
regulation of stem cell differentiationGO:200073640.018
cellular response to starvationGO:000926710.018
sensory perception of smellGO:000760820.018
positive regulation of dna metabolic processGO:005105410.018
regulation of blood pressureGO:000821710.018
positive regulation of neural precursor cell proliferationGO:200017910.018
regulation of carbohydrate metabolic processGO:000610940.018
pathway restricted smad protein phosphorylationGO:006038910.018
positive regulation of erk1 and erk2 cascadeGO:007037420.018
cell substrate junction assemblyGO:000704420.018
mitochondrion organizationGO:000700540.017
cellular modified amino acid metabolic processGO:000657530.017
regulation of circadian rhythmGO:004275240.017
regulation of synapse assemblyGO:005196330.017
meiotic chromosome segregationGO:004513230.017
regulation of exocytosisGO:001715710.017
glucose homeostasisGO:004259310.017
cell cycle processGO:0022402530.017
cell projection assemblyGO:0030031640.017
positive regulation of stress activated mapk cascadeGO:003287430.017
ovulation cycleGO:004269820.017
regulation of vasculature developmentGO:1901342330.017
morphogenesis of an epithelial sheetGO:0002011490.017
leukocyte migrationGO:0050900150.017
heart processGO:0003015710.017
dorsal ventral pattern formationGO:00099531250.017
catecholamine metabolic processGO:000658420.017
negative regulation of small gtpase mediated signal transductionGO:005105810.017
blood circulationGO:0008015870.017
mesenchyme developmentGO:00604851270.017
ovulation cycle processGO:002260220.017
hormone transportGO:000991420.016
regulation of cell growthGO:0001558290.016
nephron epithelium morphogenesisGO:007208810.016
muscle cell migrationGO:001481240.016
regulation of protein ubiquitinationGO:003139630.016
positive regulation of lipid metabolic processGO:004583410.016
cellular localizationGO:0051641970.016
cellular ketone metabolic processGO:0042180110.016
regulation of transcription from rna polymerase ii promoter in response to oxidative stressGO:004361900.016
regulation of gene expressionGO:00104682650.016
stem cell differentiationGO:00488631170.016
macromolecule localizationGO:0033036540.016
positive regulation of multicellular organismal processGO:0051240520.016
negative regulation of neural precursor cell proliferationGO:200017810.016
regulation of transmembrane transporter activityGO:002289820.016
regulation of immune system processGO:0002682340.016
cellular carbohydrate metabolic processGO:004426240.016
lipid catabolic processGO:001604240.016
cation transmembrane transportGO:0098655650.016
cellular response to stressGO:0033554620.016
neurotransmitter secretionGO:000726920.016
regulation of cell migrationGO:0030334400.016
dna templated transcription initiationGO:000635210.016
sensory perceptionGO:0007600390.016
female gonad developmentGO:000858540.015
astrocyte differentiationGO:004870810.015
eye morphogenesisGO:00485921440.015
protein homooligomerizationGO:005126030.015
regulation of phospholipase activityGO:001051720.015
negative regulation of programmed cell deathGO:0043069580.015
negative regulation of nucleocytoplasmic transportGO:004682320.015
regulation of nervous system developmentGO:0051960900.015
regulation of protein metabolic processGO:0051246560.015
female sex differentiationGO:004666040.015
stem cell developmentGO:0048864820.015
notch signaling pathwayGO:0007219350.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.015
embryonic skeletal system morphogenesisGO:0048704930.015
regulation of blood vessel sizeGO:005088020.015
multicellular organismal response to stressGO:003355520.015
positive regulation of programmed cell deathGO:0043068290.015
negative regulation of transcription dna templatedGO:0045892450.015
single organism cellular localizationGO:1902580460.015
glomerulus developmentGO:0032835270.015
embryonic heart tube morphogenesisGO:00031431080.015
response to uvGO:000941130.015
regulation of organ growthGO:004662030.015
negative regulation of epithelial cell proliferationGO:005068010.015
positive regulation of muscle cell differentiationGO:005114910.015
regulation of molecular functionGO:0065009700.015
glucose importGO:004632320.015
cellular response to extracellular stimulusGO:003166820.015
retina development in camera type eyeGO:00600411460.015
regulation of dendrite morphogenesisGO:004881430.015
regulation of purine nucleotide catabolic processGO:003312120.015
response to alkaloidGO:004327920.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.014
cell fate specificationGO:0001708680.014
ion transportGO:00068111140.014
camera type eye developmentGO:00430102220.014
protein complex assemblyGO:0006461300.014
regulation of intracellular signal transductionGO:1902531570.014
positive regulation of cell activationGO:005086710.014
regulation of protein modification by small protein conjugation or removalGO:190332030.014
patterning of blood vesselsGO:0001569150.014
i kappab kinase nf kappab signalingGO:000724940.014
regulation of angiogenesisGO:0045765260.014
positive regulation of macromolecule biosynthetic processGO:0010557590.014
nephron morphogenesisGO:007202820.014
protein acylationGO:004354330.014
positive regulation of epithelial cell migrationGO:001063420.014
monovalent inorganic cation transportGO:0015672420.014
regulation of transportGO:0051049450.014
urogenital system developmentGO:0001655970.014
protein secretionGO:000930610.014
positive regulation of macromolecule metabolic processGO:0010604930.014
negative regulation of protein import into nucleusGO:004230820.014
positive regulation of transcription dna templatedGO:0045893570.014
endothelial cell proliferationGO:0001935110.014
lymphocyte proliferationGO:004665110.014
cellular protein modification processGO:00064641000.014

plekhg5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
disease of cellular proliferationDOID:1456600.018
cardiovascular system diseaseDOID:128700.017
nervous system diseaseDOID:86300.015