Danio rerio

0 known processes

smpd4

sphingomyelin phosphodiesterase 4

(Aliases: wu:fb22d05,zgc:66367,wu:fi25e10,MGC66367)

smpd4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.167
agingGO:000756820.089
cellular protein catabolic processGO:004425740.088
response to stressGO:00069502630.077
modification dependent protein catabolic processGO:001994130.070
negative regulation of cellular processGO:00485232830.065
cellular macromolecule metabolic processGO:00442603910.057
signal transductionGO:00071654550.054
negative regulation of biological processGO:00485193040.054
meiotic nuclear divisionGO:000712640.052
regulation of protein catabolic processGO:004217610.051
ubiquitin dependent protein catabolic processGO:000651130.049
proteolysis involved in cellular protein catabolic processGO:005160330.048
organelle organizationGO:00069962270.048
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.047
establishment of protein localization to organelleGO:007259440.046
modification dependent macromolecule catabolic processGO:004363230.046
regulation of biological qualityGO:00650082630.045
heterocycle biosynthetic processGO:00181302150.043
peptidyl serine phosphorylationGO:001810510.042
single organism metabolic processGO:00447102170.041
nuclear importGO:005117030.041
meiotic cell cycle processGO:190304630.040
cellular nitrogen compound biosynthetic processGO:00442712180.039
cellular amine metabolic processGO:004410620.038
positive regulation of cell cycleGO:004578730.038
proteasomal protein catabolic processGO:001049820.038
tube morphogenesisGO:00352393490.037
cellular nitrogen compound metabolic processGO:00346412900.036
cellular response to radiationGO:007147840.036
meiotic chromosome segregationGO:004513230.035
peptidyl serine modificationGO:001820920.035
regulation of signal transductionGO:00099662250.035
nuclear transportGO:005116940.035
amine metabolic processGO:000930820.034
maintenance of locationGO:005123540.034
single organism localizationGO:19025782250.033
mitotic dna integrity checkpointGO:004477440.033
response to abiotic stimulusGO:00096281220.033
response to uvGO:000941130.033
protein stabilizationGO:005082120.033
protein localization to nucleusGO:003450430.033
stem cell maintenanceGO:001982740.032
protein import into nucleusGO:000660630.032
g1 s transition of mitotic cell cycleGO:000008210.032
locomotionGO:00400113130.032
regulation of macromolecule metabolic processGO:00602553170.031
cell cycle g1 s phase transitionGO:004484310.031
response to drugGO:004249330.031
cellular protein metabolic processGO:00442671290.031
regulation of rna metabolic processGO:00512522240.031
regulation of meiotic cell cycleGO:005144510.031
gene expressionGO:00104672520.030
protein metabolic processGO:00195381830.030
protein targeting to nucleusGO:004474430.029
cellular component movementGO:00069283350.029
cellular biosynthetic processGO:00442492860.029
organic substance biosynthetic processGO:19015762890.029
lipid storageGO:001991510.029
regulation of cellular biosynthetic processGO:00313262450.029
regulation of metabolic processGO:00192223590.028
positive regulation of transportGO:005105020.028
regulation of protein transportGO:005122330.028
regulation of nitrogen compound metabolic processGO:00511712510.028
protein modification processGO:00362111000.028
nitrogen compound metabolic processGO:00068073190.028
negative regulation of catabolic processGO:000989530.028
stem cell divisionGO:001714510.028
mitotic dna damage checkpointGO:004477340.027
protein importGO:001703830.027
single organism organelle organizationGO:19025891990.027
cellular component morphogenesisGO:00329893360.027
establishment of localizationGO:00512342440.027
regulation of cellular amino acid metabolic processGO:000652100.027
regulation of gene expressionGO:00104682650.026
mitochondrion organizationGO:000700540.026
nucleocytoplasmic transportGO:000691340.026
regulation of response to stimulusGO:00485832690.026
single organism nuclear importGO:190259330.026
spindle assemblyGO:005122520.026
regulation of establishment of protein localizationGO:007020140.026
regulation of cellular amine metabolic processGO:003323800.026
macromolecule biosynthetic processGO:00090592270.026
transcription dna templatedGO:00063511810.026
nucleic acid templated transcriptionGO:00976591810.026
intracellular signal transductionGO:0035556850.026
regulation of cytoplasmic transportGO:190364940.025
cellular aromatic compound metabolic processGO:00067252950.025
rna biosynthetic processGO:00327741810.025
cellular component biogenesisGO:00440851780.025
sensory organ developmentGO:00074233930.024
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.024
regulation of intracellular protein transportGO:003315730.024
positive regulation of catabolic processGO:000989640.024
neuron differentiationGO:00301823530.024
nucleobase containing compound metabolic processGO:00061392740.024
female sex differentiationGO:004666040.024
meiosis iGO:000712710.024
response to external stimulusGO:00096052640.024
response to chemicalGO:00422213200.024
multicellular organism growthGO:003526440.024
regulation of cell communicationGO:00106462320.023
cell morphogenesisGO:00009022890.023
generation of neuronsGO:00486993850.023
regulation of protein import into nucleusGO:004230620.023
nucleobase containing compound biosynthetic processGO:00346542050.023
organic cyclic compound metabolic processGO:19013603010.023
regulation of cell shapeGO:000836010.023
growthGO:00400071740.023
regulation of protein targetingGO:190353320.022
regulation of transcription dna templatedGO:00063552130.022
regulation of multicellular organism growthGO:004001440.022
negative regulation of protein phosphorylationGO:000193340.022
development of primary female sexual characteristicsGO:004654540.022
response to radiationGO:0009314510.022
regulation of macromolecule biosynthetic processGO:00105562250.022
g2 dna damage checkpointGO:003157230.022
cellular macromolecule biosynthetic processGO:00346452240.022
female gonad developmentGO:000858540.021
cellular component assemblyGO:00226071700.021
regulation of cellular metabolic processGO:00313233200.021
rna localizationGO:000640340.021
stem cell proliferationGO:007208940.021
regulation of bindingGO:005109830.021
cellular component disassemblyGO:002241110.021
microtubule organizing center organizationGO:003102310.021
extrinsic apoptotic signaling pathwayGO:009719130.020
regulation of protein complex assemblyGO:004325430.020
negative regulation of cellular catabolic processGO:003133030.020
regulation of protein localization to nucleusGO:190018020.020
regulation of multicellular organismal processGO:00512392770.020
regulation of nucleocytoplasmic transportGO:004682220.020
regulation of biosynthetic processGO:00098892500.020
phosphate containing compound metabolic processGO:00067961080.020
neuron developmentGO:00486662620.020
regionalizationGO:00030022740.020
regulation of cellular ketone metabolic processGO:001056570.020
cellular response to external stimulusGO:007149620.020
positive regulation of cellular component biogenesisGO:004408930.020
macromolecular complex disassemblyGO:003298410.020
regulation of protein ubiquitinationGO:003139630.019
macromolecule modificationGO:00434121110.019
regulation of primary metabolic processGO:00800903110.019
positive regulation of biological processGO:00485182530.019
cytokinesisGO:000091030.019
cellular protein modification processGO:00064641000.019
nuclear exportGO:005116810.019
embryo development ending in birth or egg hatchingGO:00097922710.019
production of molecular mediator of immune responseGO:000244020.019
negative regulation of protein serine threonine kinase activityGO:007190120.019
cellular ketone metabolic processGO:0042180110.019
cellular localizationGO:0051641970.019
regulation of cellular protein catabolic processGO:190336210.019
protein acetylationGO:000647320.019
regulation of synapse assemblyGO:005196330.018
phagocytosisGO:000690930.018
embryonic organ developmentGO:00485683810.018
b cell activationGO:004211320.018
synaptic growth at neuromuscular junctionGO:005112420.018
heart developmentGO:00075073130.018
transportGO:00068102200.018
phosphorus metabolic processGO:00067931090.018
gtp metabolic processGO:004603940.018
regulation of signalingGO:00230512350.018
small molecule metabolic processGO:0044281770.018
aromatic compound biosynthetic processGO:00194382170.018
cell projection organizationGO:00300302840.018
locomotor rhythmGO:004547530.018
regulation of protein modification by small protein conjugation or removalGO:190332030.018
heterocycle metabolic processGO:00464832900.017
regulation of cellular macromolecule biosynthetic processGO:20001122220.017
cognitionGO:005089010.017
rna metabolic processGO:00160702190.017
positive regulation of cellular amine metabolic processGO:003324000.017
regulation of chromosome segregationGO:005198310.017
single organism transportGO:00447652060.017
positive regulation of canonical wnt signaling pathwayGO:009026340.017
regulation of cell activationGO:005086510.017
nucleic acid metabolic processGO:00903042440.017
central nervous system developmentGO:00074173870.017
axonogenesisGO:00074091520.017
negative regulation of mapk cascadeGO:004340940.017
eye developmentGO:00016542770.017
cellular amino acid metabolic processGO:000652070.017
synaptic target recognitionGO:000803910.017
response to monosaccharideGO:003428430.017
regulation of synapse organizationGO:005080730.016
organonitrogen compound metabolic processGO:1901564740.016
regulation of cytokine productionGO:000181730.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
cellular response to extracellular stimulusGO:003166820.016
brain developmentGO:00074202930.016
cell projection morphogenesisGO:00488582440.016
regulation of jak stat cascadeGO:004642530.016
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.016
cell agingGO:000756920.016
gastrulationGO:00073692080.016
regulation of intracellular signal transductionGO:1902531570.016
positive regulation of cytoskeleton organizationGO:005149530.016
regulation of translational initiationGO:000644610.016
regulation of rna biosynthetic processGO:20011412130.016
internal protein amino acid acetylationGO:000647520.016
positive regulation of cytokine productionGO:000181920.016
tissue remodelingGO:004877140.016
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of nucleic acid templated transcriptionGO:19035062130.016
negative regulation of kinase activityGO:003367340.016
localization of cellGO:00516742440.015
regulation of cellular component organizationGO:0051128860.015
oxoacid metabolic processGO:0043436310.015
organelle assemblyGO:00709251100.015
regulation of peptidyl tyrosine phosphorylationGO:005073010.015
cell migrationGO:00164772370.015
positive regulation of cell adhesionGO:004578510.015
primary neural tube formationGO:001402010.015
centrosome organizationGO:005129710.015
peptidyl lysine acetylationGO:001839420.015
cell part morphogenesisGO:00329902460.015
negative regulation of protein kinase activityGO:000646940.015
internal peptidyl lysine acetylationGO:001839320.015
gtp catabolic processGO:000618420.015
cell substrate adhesionGO:003158940.015
response to carbohydrateGO:000974330.015
regulation of neural precursor cell proliferationGO:200017730.015
cellular carbohydrate metabolic processGO:004426240.015
positive regulation of metabolic processGO:00098931080.015
regulation of synaptic plasticityGO:004816710.015
system processGO:00030081850.015
response to hexoseGO:000974630.015
organic acid metabolic processGO:0006082310.015
protein complex disassemblyGO:004324110.015
head developmentGO:00603223030.015
guanosine containing compound metabolic processGO:190106840.015
response to light stimulusGO:0009416460.015
protein polymerizationGO:005125840.014
positive regulation of erk1 and erk2 cascadeGO:007037420.014
erk1 and erk2 cascadeGO:007037140.014
somatic muscle developmentGO:000752540.014
post embryonic organ developmentGO:004856940.014
regulation of circadian rhythmGO:004275240.014
cell matrix adhesionGO:000716040.014
regulation of developmental processGO:00507932470.014
cell proliferationGO:0008283800.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.014
cell motilityGO:00488702440.014
regulation of stem cell proliferationGO:007209120.014
cell migration involved in gastrulationGO:0042074790.014
entrainment of circadian clockGO:000964920.014
regulation of protein complex disassemblyGO:004324410.014
regulation of inflammatory responseGO:005072720.014
response to external biotic stimulusGO:0043207970.014
protein localization to plasma membraneGO:007265910.014
protein secretionGO:000930610.014
biosynthetic processGO:00090582940.014
regulation of cell differentiationGO:00455951420.014
centrosome duplicationGO:005129810.014
cellular response to starvationGO:000926710.013
regulation of purine nucleotide catabolic processGO:003312120.013
regulation of stem cell differentiationGO:200073640.013
protein acylationGO:004354330.013
cytoskeleton organizationGO:0007010960.013
chordate embryonic developmentGO:00430092710.013
translational initiationGO:000641330.013
positive regulation of translationGO:004572710.013
phosphorylationGO:0016310690.013
microtubule cytoskeleton organization involved in mitosisGO:190285010.013
positive regulation of cellular catabolic processGO:003133130.013
exocytosisGO:000688710.013
regulation of nucleotide catabolic processGO:003081120.013
carboxylic acid metabolic processGO:0019752220.013
secondary metabolic processGO:001974830.013
regulation of localizationGO:00328791040.013
somatic stem cell maintenanceGO:003501910.013
negative regulation of dna metabolic processGO:005105340.013
mitotic g2 dna damage checkpointGO:000709530.013
adult behaviorGO:003053420.013
spermatid differentiationGO:004851520.013
regulation of response to extracellular stimulusGO:003210410.013
activation of mapk activityGO:000018730.013
regulation of protein bindingGO:004339330.013
limb bud formationGO:006017420.013
transcription from rna polymerase ii promoterGO:0006366800.013
negative regulation of macromolecule metabolic processGO:0010605760.012
response to glucoseGO:000974930.012
digestive tract morphogenesisGO:00485462310.012
male meiosisGO:000714020.012
heart morphogenesisGO:00030071560.012
epithelial tube morphogenesisGO:00605621480.012
negative chemotaxisGO:005091910.012
digestive tract developmentGO:00485652650.012
enzyme linked receptor protein signaling pathwayGO:00071671060.012
specification of symmetryGO:00097992040.012
response to biotic stimulusGO:0009607970.012
carbohydrate homeostasisGO:003350010.012
sequestering of calcium ionGO:005120830.012
regulation of nucleoside metabolic processGO:000911820.012
specification of axis polarityGO:006500140.012
ribosome assemblyGO:004225510.012
cellular response to stressGO:0033554620.012
regulation of microtubule cytoskeleton organizationGO:007050730.012
camera type eye developmentGO:00430102220.012
skeletal system developmentGO:00015011810.012
somatic cell dna recombinationGO:001644410.012
anterior posterior pattern specificationGO:00099521520.012
negative regulation of nuclear divisionGO:005178430.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
positive regulation of cell activationGO:005086710.012
regulation of protein metabolic processGO:0051246560.012
b cell differentiationGO:003018310.012
guanosine containing compound catabolic processGO:190106920.012
positive regulation of map kinase activityGO:004340630.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
digestive system developmentGO:00551232890.012
endosomal transportGO:001619720.012
positive regulation of secretionGO:005104710.012
regulation of nucleobase containing compound metabolic processGO:00192192500.012
chromosome organization involved in meiosisGO:007019210.012
vacuolar transportGO:000703420.012
sleepGO:003043110.012
lateral inhibitionGO:004633110.012
positive regulation of stem cell proliferationGO:200064810.012
regulation of gtp catabolic processGO:003312420.012
regulation of reactive oxygen species metabolic processGO:200037720.011
negative regulation of chromosome organizationGO:200125110.011
cellular response to oxygen levelsGO:007145310.011
compound eye developmentGO:004874920.011
rna transportGO:005065820.011
regulation of organelle assemblyGO:190211540.011
female meiotic divisionGO:000714320.011
sensory organ morphogenesisGO:00905962000.011
cellular response to biotic stimulusGO:007121630.011
neuron projection developmentGO:00311751800.011
response to corticosteroidGO:003196010.011
regulation of epithelial cell proliferationGO:005067830.011
neuroblast proliferationGO:000740520.011
reactive nitrogen species metabolic processGO:200105700.011
pharyngeal muscle developmentGO:004328240.011
regulation of cell matrix adhesionGO:000195210.011
positive regulation of secretion by cellGO:190353210.011
golgi vesicle transportGO:004819330.011
leukocyte proliferationGO:007066110.011
nucleoside monophosphate catabolic processGO:000912540.011
regulation of cellular protein metabolic processGO:0032268520.011
regulation of gtpase activityGO:004308720.011
nitric oxide biosynthetic processGO:000680920.011
reactive oxygen species biosynthetic processGO:190340910.011
regulation of response to nutrient levelsGO:003210710.011
nucleic acid transportGO:005065720.011
protein phosphorylationGO:0006468470.011
response to nutrientGO:000758430.011
spermatid developmentGO:000728620.011
olfactory bulb developmentGO:002177240.011
double strand break repairGO:000630230.011
sequestering of metal ionGO:005123830.011
cell surface receptor signaling pathwayGO:00071663250.011
ameboidal type cell migrationGO:00016671430.011
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.011
negative regulation of translationGO:001714810.011
regulation of dna templated transcription elongationGO:003278430.011
hormone transportGO:000991420.011
positive regulation of dna metabolic processGO:005105410.011
cellular response to lipopolysaccharideGO:007122230.011
glucose homeostasisGO:004259310.011
positive regulation of nucleotide catabolic processGO:003081310.011
regulation of multicellular organismal developmentGO:20000262230.011
vasculature developmentGO:00019442780.011
negative regulation of metabolic processGO:0009892860.011
b cell mediated immunityGO:001972430.011
cellular response to nutrient levelsGO:003166920.011
immune system processGO:00023762410.011
protein homooligomerizationGO:005126030.011
protein depolymerizationGO:005126110.011
photoreceptor cell fate commitmentGO:004655210.010
regulation of protein polymerizationGO:003227120.010
nitric oxide metabolic processGO:004620920.010
negative regulation of sequestering of calcium ionGO:005128340.010
eye morphogenesisGO:00485921440.010
g2 m transition of mitotic cell cycleGO:000008640.010
lymphocyte proliferationGO:004665110.010
stem cell differentiationGO:00488631170.010
negative regulation of developmental processGO:0051093650.010
lamellipodium assemblyGO:003003210.010
long chain fatty acid metabolic processGO:000167610.010
response to alkaloidGO:004327920.010
sister chromatid cohesionGO:000706220.010
cell cycleGO:0007049930.010
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.010
neurological system processGO:0050877620.010
macroautophagyGO:001623610.010
autophagyGO:000691440.010
axon developmentGO:00615641660.010
regulation of erk1 and erk2 cascadeGO:007037240.010
developmental programmed cell deathGO:001062340.010
microtubule polymerization or depolymerizationGO:003110930.010
regulation of reproductive processGO:200024140.010
mesenchyme developmentGO:00604851270.010
positive regulation of immune effector processGO:000269930.010
cell substrate junction assemblyGO:000704420.010
regulation of sequestering of calcium ionGO:005128240.010
lamellipodium organizationGO:009758110.010

smpd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.017
disease of cellular proliferationDOID:1456600.017
cancerDOID:16200.017
organ system cancerDOID:005068600.017
musculoskeletal system diseaseDOID:1700.015
disease of metabolismDOID:001466700.012
sensory system diseaseDOID:005015500.011