Danio rerio

45 known processes

casp3a

caspase 3, apoptosis-related cysteine protease a

(Aliases: zgc:100890,MGC100890,casp3)

casp3a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
central nervous system developmentGO:00074173870.341
larval developmentGO:000216420.338
response to stressGO:00069502630.280
Mouse
generation of neuronsGO:00486993850.187
tube morphogenesisGO:00352393490.178
brain developmentGO:00074202930.170
head developmentGO:00603223030.167
agingGO:000756820.159
cell migration involved in gastrulationGO:0042074790.157
cellular response to external stimulusGO:007149620.143
signal transductionGO:00071654550.137
Mouse
positive regulation of transportGO:005105020.132
regulation of biological qualityGO:00650082630.131
Human Mouse
morphogenesis of an epitheliumGO:00020093330.117
digestive tract morphogenesisGO:00485462310.114
embryo development ending in birth or egg hatchingGO:00097922710.114
organic substance transportGO:0071702580.106
regulation of axonogenesisGO:0050770320.101
regulation of establishment of protein localizationGO:007020140.098
single organism localizationGO:19025782250.096
cell deathGO:00082191210.095
cell surface receptor signaling pathwayGO:00071663250.095
Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.094
gastrulationGO:00073692080.093
immune system processGO:00023762410.090
Human Mouse
multicellular organism growthGO:003526440.083
epithelial tube morphogenesisGO:00605621480.083
digestive system developmentGO:00551232890.082
positive regulation of biological processGO:00485182530.079
regulation of multicellular organism growthGO:004001440.075
establishment of localizationGO:00512342440.075
determination of bilateral symmetryGO:00098552040.075
protein localizationGO:0008104400.074
negative regulation of biological processGO:00485193040.070
Human Mouse
ameboidal type cell migrationGO:00016671430.069
secondary metabolic processGO:001974830.067
nucleocytoplasmic transportGO:000691340.066
phagocytosisGO:000690930.066
response to woundingGO:00096111160.065
Mouse
positive regulation of catabolic processGO:000989640.064
digestive tract developmentGO:00485652650.064
positive regulation of secretion by cellGO:190353210.063
stem cell maintenanceGO:001982740.062
regulation of protein transportGO:005122330.062
regulation of synapse organizationGO:005080730.062
embryonic organ developmentGO:00485683810.062
nuclear transportGO:005116940.059
cell motilityGO:00488702440.058
nitrogen compound metabolic processGO:00068073190.056
Mouse
positive regulation of apoptotic processGO:0043065290.056
nucleic acid templated transcriptionGO:00976591810.055
blood vessel morphogenesisGO:00485142160.055
rna metabolic processGO:00160702190.054
determination of left right symmetryGO:00073681790.054
cellular nitrogen compound metabolic processGO:00346412900.052
Mouse
transcription dna templatedGO:00063511810.052
protein localization to plasma membraneGO:007265910.052
regulation of cellular biosynthetic processGO:00313262450.051
immune system developmentGO:00025201910.051
Human
organic cyclic compound metabolic processGO:19013603010.050
Mouse
blood vessel developmentGO:00015682460.049
central nervous system projection neuron axonogenesisGO:0021952150.049
regulation of gene expressionGO:00104682650.048
regulation of cell communicationGO:00106462320.048
cellular catabolic processGO:0044248270.048
Mouse
specification of symmetryGO:00097992040.048
biosynthetic processGO:00090582940.047
negative regulation of apoptotic processGO:0043066550.047
Human
actin filament organizationGO:0007015150.046
cellular response to extracellular stimulusGO:003166820.046
axonogenesisGO:00074091520.046
calcium mediated signalingGO:001972220.045
positive regulation of secretionGO:005104710.045
chordate embryonic developmentGO:00430092710.045
astrocyte differentiationGO:004870810.044
heterocycle metabolic processGO:00464832900.044
Mouse
heterocycle biosynthetic processGO:00181302150.044
gene expressionGO:00104672520.043
Mouse
regulation of signal transductionGO:00099662250.043
regulation of signalingGO:00230512350.043
positive regulation of cellular biosynthetic processGO:0031328680.043
lipid storageGO:001991510.043
oxoacid metabolic processGO:0043436310.043
positive regulation of cellular processGO:00485222010.042
cellular response to xenobiotic stimulusGO:0071466350.042
response to monosaccharideGO:003428430.042
apoptotic processGO:00069151160.042
regulation of purine nucleotide catabolic processGO:003312120.041
gland developmentGO:00487321430.041
regulation of response to stimulusGO:00485832690.040
response to chemicalGO:00422213200.040
regulation of primary metabolic processGO:00800903110.040
Mouse
neuroblast proliferationGO:000740520.040
hematopoietic or lymphoid organ developmentGO:00485341910.040
Human
regulation of reactive oxygen species metabolic processGO:200037720.039
axon developmentGO:00615641660.039
regulation of nucleobase containing compound metabolic processGO:00192192500.039
Mouse
embryonic heart tube developmentGO:00350501330.038
cellular biosynthetic processGO:00442492860.038
wound healingGO:0042060900.037
locomotionGO:00400113130.037
nucleobase containing compound metabolic processGO:00061392740.037
Mouse
t cell activationGO:004211060.037
Mouse
guanosine containing compound metabolic processGO:190106840.037
cell morphogenesisGO:00009022890.037
adult behaviorGO:003053420.037
meiotic cell cycle processGO:190304630.037
cellular nitrogen compound biosynthetic processGO:00442712180.036
regulation of macromolecule biosynthetic processGO:00105562250.036
aromatic compound biosynthetic processGO:00194382170.036
mononuclear cell proliferationGO:003294310.035
Mouse
developmental programmed cell deathGO:001062340.035
positive regulation of cellular catabolic processGO:003133130.035
growthGO:00400071740.035
programmed cell deathGO:00125011190.035
small molecule metabolic processGO:0044281770.035
heart developmentGO:00075073130.035
Mouse
notch signaling pathwayGO:0007219350.034
kidney developmentGO:0001822920.034
negative regulation of response to stimulusGO:00485851040.034
negative regulation of signalingGO:0023057960.034
transportGO:00068102200.034
regulation of synapse assemblyGO:005196330.033
protein secretionGO:000930610.033
regulation of bindingGO:005109830.033
regulation of nucleic acid templated transcriptionGO:19035062130.033
carboxylic acid metabolic processGO:0019752220.033
protein import into nucleusGO:000660630.033
multi organism processGO:00517041340.032
autophagyGO:000691440.032
single organism transportGO:00447652060.032
protein localization to nucleusGO:003450430.032
cell cycle processGO:0022402530.032
regulation of apoptotic processGO:0042981980.032
positive regulation of nucleobase containing compound metabolic processGO:0045935690.032
gtp catabolic processGO:000618420.032
cellular response to organic substanceGO:00713101050.031
vasculature developmentGO:00019442780.031
epithelial cell differentiationGO:00308551160.031
Mouse
inner ear developmentGO:00488391260.031
cellular macromolecule metabolic processGO:00442603910.031
Mouse
regulation of cell shapeGO:000836010.031
macromolecule localizationGO:0033036540.031
neuron differentiationGO:00301823530.031
positive regulation of cell cycleGO:004578730.030
stem cell proliferationGO:007208940.030
actin cytoskeleton organizationGO:0030036630.030
localization of cellGO:00516742440.030
response to glucoseGO:000974930.030
negative regulation of signal transductionGO:0009968940.030
maintenance of locationGO:005123540.029
transcription from rna polymerase ii promoterGO:0006366800.029
gtp metabolic processGO:004603940.029
positive regulation of apoptotic signaling pathwayGO:200123510.029
skin developmentGO:0043588540.029
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.029
organic acid metabolic processGO:0006082310.028
protein importGO:001703830.028
guanosine containing compound catabolic processGO:190106920.028
regulation of meiotic cell cycleGO:005144510.028
regulation of filopodium assemblyGO:005148920.028
sensory organ morphogenesisGO:00905962000.028
cell migrationGO:00164772370.028
organic cyclic compound biosynthetic processGO:19013622230.028
positive regulation of cell adhesionGO:004578510.027
hemopoiesisGO:00300971830.027
Human
establishment of protein localization to plasma membraneGO:009000210.027
positive regulation of transcription dna templatedGO:0045893570.027
b cell activationGO:004211320.027
Mouse
single organism organelle organizationGO:19025891990.027
membrane invaginationGO:001032410.027
positive regulation of cellular component biogenesisGO:004408930.027
extrinsic apoptotic signaling pathwayGO:009719130.026
Mouse
renal system developmentGO:0072001940.026
organelle organizationGO:00069962270.026
Mouse
positive regulation of map kinase activityGO:004340630.026
cellular aromatic compound metabolic processGO:00067252950.026
Mouse
negative regulation of programmed cell deathGO:0043069580.026
Human
lipid digestionGO:004424130.026
regulation of programmed cell deathGO:00430671010.025
stem cell divisionGO:001714510.025
regulation of nucleotide catabolic processGO:003081120.025
cilium morphogenesisGO:0060271850.025
meiotic nuclear divisionGO:000712640.024
neuron developmentGO:00486662620.024
cellular response to chemical stimulusGO:00708871570.024
embryonic heart tube morphogenesisGO:00031431080.024
neural tube patterningGO:0021532330.024
cell projection organizationGO:00300302840.024
positive regulation of cell deathGO:0010942290.024
cellular component movementGO:00069283350.023
lymphocyte proliferationGO:004665110.023
Mouse
central nervous system neuron axonogenesisGO:0021955180.023
hepaticobiliary system developmentGO:0061008980.023
exocrine system developmentGO:0035272280.023
ras protein signal transductionGO:000726570.023
hormone transportGO:000991420.023
intestinal cholesterol absorptionGO:003029920.022
rna biosynthetic processGO:00327741810.022
urogenital system developmentGO:0001655970.022
response to external stimulusGO:00096052640.022
small gtpase mediated signal transductionGO:000726480.022
regulation of cell deathGO:00109411030.022
deathGO:00162651210.022
response to organic substanceGO:00100331530.022
epidermis developmentGO:0008544480.022
Mouse
intracellular signal transductionGO:0035556850.022
Mouse
liver developmentGO:0001889960.022
rho protein signal transductionGO:000726650.022
defense responseGO:0006952470.022
mitotic cell cycleGO:0000278640.022
reproductive processGO:0022414400.022
lateral inhibitionGO:004633110.021
response to hexoseGO:000974630.021
regulation of i kappab kinase nf kappab signalingGO:004312240.021
cell projection morphogenesisGO:00488582440.021
regulation of gtp catabolic processGO:003312420.021
proteasomal protein catabolic processGO:001049820.021
regulation of wound healingGO:006104120.021
cell part morphogenesisGO:00329902460.021
regulation of cell projection assemblyGO:006049140.021
tissue regenerationGO:0042246740.021
microtubule based processGO:0007017600.021
regulation of intracellular protein transportGO:003315730.020
microtubule based movementGO:0007018330.020
cellular response to stressGO:0033554620.020
Mouse
single organism metabolic processGO:00447102170.020
response to external biotic stimulusGO:0043207970.020
regulation of localizationGO:00328791040.020
neuron projection developmentGO:00311751800.020
cellular macromolecule biosynthetic processGO:00346452240.020
cell morphogenesis involved in differentiationGO:00009041950.020
intestinal absorptionGO:005089220.020
regulation of nitrogen compound metabolic processGO:00511712510.020
Mouse
convergent extensionGO:00600261180.020
organism emergence from protective structureGO:007168440.019
heart morphogenesisGO:00030071560.019
cortical actin cytoskeleton organizationGO:003086610.019
hatchingGO:003518840.019
olfactory bulb developmentGO:002177240.019
wnt signaling pathwayGO:0016055800.019
regulation of multicellular organismal developmentGO:20000262230.019
regulation of myotube differentiationGO:001083020.019
regulation of protein localization to plasma membraneGO:190307610.019
organonitrogen compound metabolic processGO:1901564740.019
lamellipodium assemblyGO:003003210.019
glial cell migrationGO:000834730.019
regulation of nucleoside metabolic processGO:000911820.018
regulation of developmental processGO:00507932470.018
regulation of epithelial cell proliferationGO:005067830.018
circulatory system processGO:0003013870.018
peptidyl serine modificationGO:001820920.018
cellular component morphogenesisGO:00329893360.018
negative regulation of protein phosphorylationGO:000193340.018
Mouse
regulation of extrinsic apoptotic signaling pathwayGO:200123630.018
regulation of nucleocytoplasmic transportGO:004682220.018
axon ensheathment in central nervous systemGO:003229120.018
protein acetylationGO:000647320.018
angiogenesisGO:00015251580.018
nuclear importGO:005117030.018
regulation of cell motilityGO:2000145460.018
response to xenobiotic stimulusGO:0009410450.017
protein acylationGO:004354330.017
positive regulation of rna biosynthetic processGO:1902680570.017
cell cycle g1 s phase transitionGO:004484310.017
regulation of macromolecule metabolic processGO:00602553170.017
Mouse
response to amino acidGO:004320020.017
macromolecule modificationGO:00434121110.017
Mouse
central nervous system neuron developmentGO:0021954290.017
cellular carbohydrate metabolic processGO:004426240.017
apoptotic process involved in developmentGO:190274220.017
regulation of rna metabolic processGO:00512522240.017
epibolyGO:0090504410.017
system processGO:00030081850.017
Mouse
hindbrain developmentGO:0030902910.017
regulation of mitochondrion organizationGO:001082110.017
regionalizationGO:00030022740.016
homeostasis of number of cellsGO:0048872620.016
Human Mouse
melanin metabolic processGO:000658220.016
leukocyte proliferationGO:007066110.016
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769380.016
negative regulation of macromolecule metabolic processGO:0010605760.016
Mouse
response to carbohydrateGO:000974330.016
dorsal ventral pattern formationGO:00099531250.016
spermatid differentiationGO:004851520.016
carbohydrate derivative metabolic processGO:1901135610.016
positive regulation of nucleoside metabolic processGO:004597910.016
cellular response to lipopolysaccharideGO:007122230.016
positive regulation of translationGO:004572710.016
regulation of establishment of protein localization to plasma membraneGO:009000310.016
multicellular organismal signalingGO:0035637220.016
cell agingGO:000756920.016
positive regulation of cellular amine metabolic processGO:003324000.016
positive regulation of nucleotide catabolic processGO:003081310.015
peptidyl lysine acetylationGO:001839420.015
regulation of cellular amino acid metabolic processGO:000652100.015
establishment of protein localization to organelleGO:007259440.015
establishment of endothelial barrierGO:006102830.015
chemosensory behaviorGO:000763510.015
regulation of multicellular organismal processGO:00512392770.015
negative regulation of multicellular organismal processGO:0051241690.015
sensory organ developmentGO:00074233930.015
amine metabolic processGO:000930820.015
cellular lipid metabolic processGO:0044255360.015
cellular component assemblyGO:00226071700.015
cellular response to nutrient levelsGO:003166920.015
action potentialGO:0001508190.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
regulation of cellular carbohydrate metabolic processGO:001067540.015
aorta developmentGO:003590440.015
organic substance biosynthetic processGO:19015762890.015
regulation of rna biosynthetic processGO:20011412130.015
mitochondrion organizationGO:000700540.015
Mouse
epithelial cell developmentGO:0002064420.015
regulation of neurogenesisGO:0050767870.015
hormone secretionGO:004687920.015
ear developmentGO:00435831270.015
positive regulation of cellular metabolic processGO:0031325940.015
regulation of transcription dna templatedGO:00063552130.014
regulation of establishment of planar polarityGO:009017540.014
neurotransmitter secretionGO:000726920.014
embryonic limb morphogenesisGO:003032620.014
single organism nuclear importGO:190259330.014
protein polymerizationGO:005125840.014
enzyme linked receptor protein signaling pathwayGO:00071671060.014
cell proliferationGO:0008283800.014
Mouse
regulation of protein catabolic processGO:004217610.014
positive regulation of gtpase activityGO:004354710.014
positive regulation of protein complex assemblyGO:003133420.014
heart loopingGO:0001947940.014
cell morphogenesis involved in neuron differentiationGO:00486671630.014
positive regulation of response to stimulusGO:0048584800.014
fin morphogenesisGO:0033334530.014
cellular localizationGO:0051641970.014
determination of ventral identityGO:0048264210.014
regenerationGO:0031099910.014
exocytosisGO:000688710.014
synaptic growth at neuromuscular junctionGO:005112420.014
nucleic acid metabolic processGO:00903042440.014
Mouse
cellular response to biotic stimulusGO:007121630.014
regulation of skeletal muscle tissue developmentGO:004864140.014
olfactory lobe developmentGO:002198840.014
actin polymerization or depolymerizationGO:000815420.014
cell activationGO:0001775160.014
Mouse
regulation of neuron differentiationGO:0045664560.014
phosphorus metabolic processGO:00067931090.014
Mouse
alcohol biosynthetic processGO:004616520.014
female meiotic divisionGO:000714320.013
neural precursor cell proliferationGO:0061351200.013
germ line stem cell maintenanceGO:003071820.013
cellular response to starvationGO:000926710.013
macromolecule biosynthetic processGO:00090592270.013
i kappab kinase nf kappab signalingGO:000724940.013
auditory receptor cell fate commitmentGO:000991240.013
positive regulation of rna metabolic processGO:0051254590.013
cellular response to molecule of bacterial originGO:007121930.013
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.013
peripheral nervous system developmentGO:0007422550.013
regulation of oligodendrocyte differentiationGO:004871310.013
negative regulation of epithelial cell proliferationGO:005068010.013
single organismal cell cell adhesionGO:0016337290.013
g1 s transition of mitotic cell cycleGO:000008210.013
centrosome organizationGO:005129710.013
cellular amine metabolic processGO:004410620.013
regulation of metabolic processGO:00192223590.013
Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.013
mitotic cell cycle processGO:1903047480.013
cortical cytoskeleton organizationGO:003086510.013
lipid catabolic processGO:001604240.013
peripheral nervous system neuron differentiationGO:0048934280.013
organic hydroxy compound transportGO:0015850140.013
fin developmentGO:0033333770.013
regulation of reproductive processGO:200024140.013
macromolecular complex subunit organizationGO:0043933740.013
axon guidanceGO:0007411860.013
protein complex localizationGO:003150310.013
cytoskeleton organizationGO:0007010960.013
negative regulation of cellular processGO:00485232830.013
Human Mouse
cellular protein modification processGO:00064641000.012
Mouse
response to hydrogen peroxideGO:004254230.012
response to biotic stimulusGO:0009607970.012
single organism cell adhesionGO:0098602290.012
response to other organismGO:0051707970.012
long chain fatty acid transportGO:001590910.012
retina morphogenesis in camera type eyeGO:0060042790.012
regulation of apoptotic signaling pathwayGO:2001233120.012
forebrain cell migrationGO:002188510.012
regulation of cytoplasmic transportGO:190364940.012
segmentationGO:0035282970.012
regulation of protein complex assemblyGO:004325430.012
positive regulation of nucleic acid templated transcriptionGO:1903508570.012
establishment of localization in cellGO:0051649770.012
cellular response to endogenous stimulusGO:0071495680.012
positive regulation of macromolecule biosynthetic processGO:0010557590.012
peptide transportGO:001583310.012
regulation of transcription from rna polymerase ii promoterGO:00063571140.012
response to hypoxiaGO:0001666250.012
cell cell signalingGO:0007267520.012
cell migration involved in heart developmentGO:0060973220.012
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.012
cellular ketone metabolic processGO:0042180110.012
response to uvGO:000941130.012
Mouse
response to nutrientGO:000758430.012
establishment or maintenance of cell polarityGO:0007163290.012
phosphate containing compound metabolic processGO:00067961080.012
Mouse
regulation of nervous system developmentGO:0051960900.012
transmission of nerve impulseGO:0019226190.012
positive regulation of wound healingGO:009030310.012
cellular response to hormone stimulusGO:0032870390.012
eye morphogenesisGO:00485921440.012
inner ear receptor cell fate commitmentGO:006012040.012
peptidyl serine phosphorylationGO:001810510.012
motor neuron axon guidanceGO:0008045230.012
apoptotic signaling pathwayGO:0097190230.012
Mouse
endodermal cell fate determinationGO:000749320.012
regulation of cell activationGO:005086510.011
Mouse
epithelial cell migrationGO:0010631250.011
spermatid developmentGO:000728620.011
neuron projection guidanceGO:0097485860.011
regulation of protein targetingGO:190353320.011
apical protein localizationGO:004517660.011
cellular protein catabolic processGO:004425740.011
regulation of cytokine productionGO:000181730.011
negative regulation of cell deathGO:0060548600.011
Human
negative regulation of reproductive processGO:200024230.011
atp catabolic processGO:000620040.011
positive regulation of multi organism processGO:004390230.011
negative regulation of cell communicationGO:0010648960.011
regulation of stem cell differentiationGO:200073640.011
camera type eye developmentGO:00430102220.011
regulation of cell sizeGO:0008361290.011
negative chemotaxisGO:005091910.011
response to drugGO:004249330.011
cell cycle arrestGO:000705010.011
neuron projection morphogenesisGO:00488121610.011
negative regulation of synapse assemblyGO:005196420.011
multicellular organismal reproductive processGO:0048609350.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.011
Mouse
regulation of gtpase activityGO:004308720.011
reproductionGO:0000003400.011
digestive system processGO:002260090.011
negative regulation of metabolic processGO:0009892860.011
Mouse
central nervous system neuron differentiationGO:0021953740.011
negative regulation of intracellular transportGO:003238730.011
protein targeting to nucleusGO:004474430.011
negative regulation of chemotaxisGO:005092240.011
activation of mapk activityGO:000018730.011
brain morphogenesisGO:0048854180.011
gland morphogenesisGO:0022612130.011
cytokinesisGO:000091030.011
internal protein amino acid acetylationGO:000647520.011
regulation of cell developmentGO:00602841000.011
neurotransmitter transportGO:000683620.011
keratinocyte differentiationGO:003021600.011
Mouse
regulation of synaptic growth at neuromuscular junctionGO:000858210.010
regulation of cell cell adhesionGO:0022407130.010
lamellipodium organizationGO:009758110.010
carbohydrate homeostasisGO:003350010.010
lipid metabolic processGO:0006629520.010
response to vitaminGO:003327330.010
regulation of ras gtpase activityGO:003231820.010
positive regulation of biosynthetic processGO:0009891680.010
positive regulation of dna metabolic processGO:005105410.010
negative regulation of locomotionGO:0040013180.010
peripheral nervous system neuron developmentGO:0048935220.010
negative regulation of cell differentiationGO:0045596460.010
neural tube developmentGO:0021915620.010
single organism cellular localizationGO:1902580460.010
regulation of molecular functionGO:0065009700.010
Mouse
midbrain hindbrain boundary developmentGO:0030917230.010
embryonic organ morphogenesisGO:00485622740.010
endodermal digestive tract morphogenesisGO:006103120.010
regulation of establishment or maintenance of cell polarityGO:003287820.010

casp3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.023
organ system cancerDOID:005068600.013
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013
nervous system diseaseDOID:86300.011