Danio rerio

61 known processes

tbp

TATA box binding protein

(Aliases: fd20h06,wu:fd20h06,si:zc101n13.2,zgc:66213)

tbp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of metabolic processGO:00192223590.648
regulation of cellular metabolic processGO:00313233200.623
larval developmentGO:000216420.560
central nervous system developmentGO:00074173870.459
biosynthetic processGO:00090582940.452
cellular biosynthetic processGO:00442492860.427
regulation of macromolecule metabolic processGO:00602553170.373
immune system processGO:00023762410.331
regulation of gene expressionGO:00104682650.321
nucleic acid templated transcriptionGO:00976591810.304
cellular component morphogenesisGO:00329893360.285
stem cell differentiationGO:00488631170.284
regulation of primary metabolic processGO:00800903110.275
digestive tract developmentGO:00485652650.274
head developmentGO:00603223030.273
organic cyclic compound biosynthetic processGO:19013622230.273
regulation of biological qualityGO:00650082630.252
gene expressionGO:00104672520.249
regulation of biosynthetic processGO:00098892500.249
regulation of nitrogen compound metabolic processGO:00511712510.241
cellular nitrogen compound biosynthetic processGO:00442712180.235
cognitionGO:005089010.231
regulation of rna biosynthetic processGO:20011412130.229
brain developmentGO:00074202930.223
cellular hormone metabolic processGO:0034754190.223
organelle organizationGO:00069962270.221
organic substance biosynthetic processGO:19015762890.212
digestive tract morphogenesisGO:00485462310.202
heterocycle biosynthetic processGO:00181302150.197
digestive system developmentGO:00551232890.191
regulation of nucleic acid templated transcriptionGO:19035062130.185
mononuclear cell proliferationGO:003294310.185
cellular macromolecule metabolic processGO:00442603910.181
positive regulation of cellular processGO:00485222010.180
negative regulation of biological processGO:00485193040.179
cellular aldehyde metabolic processGO:000608140.178
nucleobase containing compound metabolic processGO:00061392740.175
negative regulation of cellular processGO:00485232830.172
positive regulation of nitrogen compound metabolic processGO:0051173690.169
tube morphogenesisGO:00352393490.169
system processGO:00030081850.163
positive regulation of cellular metabolic processGO:0031325940.160
maintenance of locationGO:005123540.158
positive regulation of biological processGO:00485182530.158
protein localization to nucleusGO:003450430.157
hormone biosynthetic processGO:004244630.148
heart developmentGO:00075073130.148
response to chemicalGO:00422213200.148
cellular protein metabolic processGO:00442671290.147
small molecule metabolic processGO:0044281770.147
cellular aromatic compound metabolic processGO:00067252950.144
cell morphogenesis involved in differentiationGO:00009041950.142
negative regulation of cellular biosynthetic processGO:0031327550.142
positive regulation of metabolic processGO:00098931080.137
cellular nitrogen compound metabolic processGO:00346412900.136
muscle structure developmentGO:00610611960.135
rna metabolic processGO:00160702190.135
protein targeting to nucleusGO:004474430.134
specification of symmetryGO:00097992040.127
regulation of macromolecule biosynthetic processGO:00105562250.126
regulation of cellular biosynthetic processGO:00313262450.124
homeostatic processGO:00425921420.124
regulation of nucleobase containing compound metabolic processGO:00192192500.123
amine metabolic processGO:000930820.120
germ line stem cell maintenanceGO:003071820.118
estrogen metabolic processGO:000821020.113
regulation of response to nutrient levelsGO:003210710.112
nucleobase containing compound biosynthetic processGO:00346542050.111
oxoacid metabolic processGO:0043436310.111
cellular macromolecule biosynthetic processGO:00346452240.110
response to organic substanceGO:00100331530.110
cell projection morphogenesisGO:00488582440.109
regulation of cellular amine metabolic processGO:003323800.108
organic cyclic compound metabolic processGO:19013603010.107
agingGO:000756820.106
single organism organelle organizationGO:19025891990.103
cell morphogenesisGO:00009022890.102
protein acetylationGO:000647320.101
rna biosynthetic processGO:00327741810.100
single organism metabolic processGO:00447102170.100
leukocyte proliferationGO:007066110.098
regulation of transcription from rna polymerase ii promoterGO:00063571140.097
cellular response to nutrient levelsGO:003166920.094
regulation of rna metabolic processGO:00512522240.094
cellular component assemblyGO:00226071700.094
generation of neuronsGO:00486993850.092
response to amineGO:001407510.092
single organism nuclear importGO:190259330.091
cellular ketone metabolic processGO:0042180110.090
catechol containing compound metabolic processGO:000971220.090
negative regulation of metabolic processGO:0009892860.090
internal protein amino acid acetylationGO:000647520.089
hemopoiesisGO:00300971830.087
nuclear importGO:005117030.082
morphogenesis of an epitheliumGO:00020093330.082
sensory organ developmentGO:00074233930.080
positive regulation of cellular amine metabolic processGO:003324000.080
establishment of localizationGO:00512342440.080
determination of bilateral symmetryGO:00098552040.079
neuron developmentGO:00486662620.079
regulation of erk1 and erk2 cascadeGO:007037240.075
protein import into nucleusGO:000660630.074
eye developmentGO:00016542770.074
heterocycle metabolic processGO:00464832900.072
cellular response to chemical stimulusGO:00708871570.072
cell part morphogenesisGO:00329902460.072
neuron differentiationGO:00301823530.072
retinoid metabolic processGO:0001523150.072
immune system developmentGO:00025201910.072
lymphocyte proliferationGO:004665110.071
response to drugGO:004249330.070
embryonic organ developmentGO:00485683810.069
regulation of transcription dna templatedGO:00063552130.067
establishment of protein localization to organelleGO:007259440.067
regulation of cellular macromolecule biosynthetic processGO:20001122220.066
nucleocytoplasmic transportGO:000691340.065
multicellular organism growthGO:003526440.064
cell surface receptor signaling pathwayGO:00071663250.064
localization of cellGO:00516742440.064
skeletal system developmentGO:00015011810.064
t cell differentiationGO:003021760.064
nuclear transportGO:005116940.064
neuron projection morphogenesisGO:00488121610.063
purine ribonucleoside monophosphate catabolic processGO:000916940.063
sensory perception of chemical stimulusGO:000760630.063
aromatic compound biosynthetic processGO:00194382170.063
macromolecular complex subunit organizationGO:0043933740.062
muscle organ developmentGO:00075171010.062
sensory perception of smellGO:000760820.060
cellular response to external stimulusGO:007149620.058
embryo development ending in birth or egg hatchingGO:00097922710.058
cellular amine metabolic processGO:004410620.057
developmental growthGO:00485891660.055
appendage morphogenesisGO:0035107560.055
response to stressGO:00069502630.055
determination of heart left right asymmetryGO:00613711170.054
transcription dna templatedGO:00063511810.053
cellular lipid metabolic processGO:0044255360.052
central nervous system neuron differentiationGO:0021953740.052
ameboidal type cell migrationGO:00016671430.051
positive regulation of cell killingGO:003134320.051
gastrulationGO:00073692080.050
protein acylationGO:004354330.050
positive regulation of cellular component biogenesisGO:004408930.049
establishment of localization in cellGO:0051649770.049
protein metabolic processGO:00195381830.048
hematopoietic or lymphoid organ developmentGO:00485341910.048
organic acid metabolic processGO:0006082310.048
myeloid cell developmentGO:0061515320.048
positive regulation of cell cycleGO:004578730.048
vasculature developmentGO:00019442780.048
diterpenoid biosynthetic processGO:001610270.047
positive regulation of cellular amino acid metabolic processGO:004576400.047
regulation of bindingGO:005109830.047
terpenoid metabolic processGO:0006721150.047
regulation of apoptotic processGO:0042981980.046
post embryonic organ developmentGO:004856940.046
neural crest cell differentiationGO:0014033720.046
multicellular organismal response to stressGO:003355520.045
single organism localizationGO:19025782250.044
stem cell fate commitmentGO:004886510.044
photoreceptor cell differentiationGO:0046530550.044
regulation of developmental processGO:00507932470.044
response to other organismGO:0051707970.044
fin developmentGO:0033333770.044
positive regulation of cell activationGO:005086710.044
positive regulation of biosynthetic processGO:0009891680.043
regulation of cellular ketone metabolic processGO:001056570.042
catecholamine metabolic processGO:000658420.042
mesenchymal cell differentiationGO:0048762870.042
cellular component movementGO:00069283350.042
response to retinoic acidGO:003252660.042
locomotionGO:00400113130.042
internal peptidyl lysine acetylationGO:001839320.042
microtubule based processGO:0007017600.041
embryonic heart tube morphogenesisGO:00031431080.041
chemosensory behaviorGO:000763510.041
negative regulation of response to stimulusGO:00485851040.041
nucleoside monophosphate catabolic processGO:000912540.041
adult behaviorGO:003053420.041
energy reserve metabolic processGO:000611220.040
eye morphogenesisGO:00485921440.040
positive regulation of lymphocyte mediated immunityGO:000270810.040
nitrogen compound metabolic processGO:00068073190.040
homeostasis of number of cellsGO:0048872620.040
embryonic organ morphogenesisGO:00485622740.040
dopamine metabolic processGO:004241720.040
ribonucleoside monophosphate catabolic processGO:000915840.039
gamete generationGO:0007276330.039
determination of left right symmetryGO:00073681790.039
behaviorGO:0007610740.039
response to amphetamineGO:000197510.039
isoprenoid biosynthetic processGO:000829970.039
cell morphogenesis involved in neuron differentiationGO:00486671630.038
cell projection assemblyGO:0030031640.038
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.038
cellular component assembly involved in morphogenesisGO:00109271070.038
single organism biosynthetic processGO:0044711710.038
cellular component biogenesisGO:00440851780.038
cytoskeleton organizationGO:0007010960.038
microtubule organizing center organizationGO:003102310.038
organonitrogen compound metabolic processGO:1901564740.038
cellular localizationGO:0051641970.038
neuron projection developmentGO:00311751800.037
purine nucleoside monophosphate catabolic processGO:000912840.037
cell migration involved in gastrulationGO:0042074790.037
oxidation reduction processGO:0055114410.037
stem cell proliferationGO:007208940.037
pericardium developmentGO:006003910.037
protein importGO:001703830.037
regulation of cellular amino acid metabolic processGO:000652100.037
camera type eye developmentGO:00430102220.037
collagen metabolic processGO:003296320.036
regulation of molecular functionGO:0065009700.036
negative regulation of gene expressionGO:0010629650.036
negative regulation of macromolecule metabolic processGO:0010605760.036
response to endogenous stimulusGO:0009719830.036
transcription from rna polymerase ii promoterGO:0006366800.036
positive regulation of erk1 and erk2 cascadeGO:007037420.036
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.036
deathGO:00162651210.036
single organism reproductive processGO:0044702400.036
striated muscle tissue developmentGO:00147061100.036
cellular protein modification processGO:00064641000.036
heart loopingGO:0001947940.036
hormone metabolic processGO:0042445190.036
growthGO:00400071740.035
neurological system processGO:0050877620.035
regulation of organelle assemblyGO:190211540.035
b cell activationGO:004211320.035
negative regulation of signal transductionGO:0009968940.035
regulation of cell substrate adhesionGO:001081010.035
kupffer s vesicle developmentGO:0070121500.035
regulation of cell activationGO:005086510.035
transportGO:00068102200.035
regulation of response to stimulusGO:00485832690.034
retina development in camera type eyeGO:00600411460.034
centrosome organizationGO:005129710.034
response to biotic stimulusGO:0009607970.034
single organism cellular localizationGO:1902580460.033
fat soluble vitamin metabolic processGO:000677540.033
signal transductionGO:00071654550.032
regulation of cellular carbohydrate metabolic processGO:001067540.032
protein homooligomerizationGO:005126030.032
erk1 and erk2 cascadeGO:007037140.032
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.032
regionalizationGO:00030022740.032
macromolecule biosynthetic processGO:00090592270.032
regulation of cell shapeGO:000836010.031
cell cycle g1 s phase transitionGO:004484310.031
response to carbohydrateGO:000974330.031
cellular response to extracellular stimulusGO:003166820.031
regulation of multicellular organismal processGO:00512392770.031
nucleic acid metabolic processGO:00903042440.031
positive regulation of cell communicationGO:0010647560.031
g1 s transition of mitotic cell cycleGO:000008210.031
regulation of multicellular organism growthGO:004001440.030
central nervous system neuron developmentGO:0021954290.030
regulation of i kappab kinase nf kappab signalingGO:004312240.030
cell motilityGO:00488702440.030
leukocyte homeostasisGO:000177620.030
carboxylic acid metabolic processGO:0019752220.030
pericardium morphogenesisGO:000334410.030
stem cell developmentGO:0048864820.030
response to vitaminGO:003327330.029
regulation of cell cycleGO:0051726520.029
positive regulation of catabolic processGO:000989640.029
cellular response to lipopolysaccharideGO:007122230.029
negative regulation of cell differentiationGO:0045596460.029
positive regulation of rna metabolic processGO:0051254590.029
synaptic growth at neuromuscular junctionGO:005112420.029
lipid biosynthetic processGO:0008610220.028
guanosine containing compound catabolic processGO:190106920.028
regulation of protein ubiquitinationGO:003139630.028
mitotic cell cycle processGO:1903047480.028
muscle cell migrationGO:001481240.028
regulation of response to extracellular stimulusGO:003210410.028
cellular modified amino acid metabolic processGO:000657530.028
positive regulation of immune effector processGO:000269930.028
histone modificationGO:0016570200.028
negative regulation of programmed cell deathGO:0043069580.027
organophosphate biosynthetic processGO:0090407230.027
regulation of receptor activityGO:001046920.027
stem cell maintenanceGO:001982740.027
regulation of signalingGO:00230512350.027
chordate embryonic developmentGO:00430092710.027
retina homeostasisGO:0001895120.027
multi organism processGO:00517041340.027
regulation of establishment of protein localizationGO:007020140.027
cellular amino acid metabolic processGO:000652070.027
cell deathGO:00082191210.027
regulation of cell communicationGO:00106462320.027
regulation of mapk cascadeGO:0043408140.027
positive regulation of chromatin modificationGO:190331010.027
eye photoreceptor cell differentiationGO:0001754450.027
embryonic cranial skeleton morphogenesisGO:0048701900.026
cellular carbohydrate metabolic processGO:004426240.026
cilium morphogenesisGO:0060271850.026
notch signaling pathwayGO:0007219350.026
gland developmentGO:00487321430.026
macroautophagyGO:001623610.026
phosphorus metabolic processGO:00067931090.026
cytokinesisGO:000091030.026
compound eye developmentGO:004874920.025
multicellular organismal macromolecule metabolic processGO:004425920.025
iron ion homeostasisGO:005507240.025
cell cycle processGO:0022402530.025
lipid storageGO:001991510.025
single organism behaviorGO:0044708240.025
regulation of peptidyl tyrosine phosphorylationGO:005073010.025
regulation of carbohydrate metabolic processGO:000610940.025
cell projection organizationGO:00300302840.025
endocrine system developmentGO:0035270650.024
cellular respirationGO:004533330.024
phagocytosisGO:000690930.024
cell matrix adhesionGO:000716040.024
positive regulation of carbohydrate metabolic processGO:004591310.024
erythrocyte developmentGO:0048821240.024
somatic muscle developmentGO:000752540.024
regulation of cell differentiationGO:00455951420.024
retinal metabolic processGO:004257430.024
muscle tissue developmentGO:00605371100.024
meiotic nuclear divisionGO:000712640.023
positive regulation of map kinase activityGO:004340630.023
phosphate containing compound metabolic processGO:00067961080.023
positive regulation of gene expressionGO:0010628710.023
regulation of synapse organizationGO:005080730.023
dendrite morphogenesisGO:004881350.023
epithelial cell differentiationGO:00308551160.023
regulation of signal transductionGO:00099662250.023
positive regulation of cellular catabolic processGO:003133130.023
regulation of multicellular organismal developmentGO:20000262230.022
protein dephosphorylationGO:000647030.022
negative regulation of nitrogen compound metabolic processGO:0051172590.022
purine ribonucleoside biosynthetic processGO:004612920.022
tissue homeostasisGO:0001894250.022
regulation of protein modification by small protein conjugation or removalGO:190332030.022
response to monosaccharideGO:003428430.022
rna 3 end processingGO:003112320.022
nucleotide biosynthetic processGO:0009165210.022
regulation of cytoplasmic transportGO:190364940.022
positive regulation of leukocyte mediated immunityGO:000270510.022
regulation of dendrite developmentGO:005077330.022
single organism transportGO:00447652060.022
positive regulation of jnk cascadeGO:004633030.022
dicarboxylic acid metabolic processGO:004364810.021
response to external biotic stimulusGO:0043207970.021
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.021
blood vessel developmentGO:00015682460.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
positive regulation of macromolecule metabolic processGO:0010604930.021
photoreceptor cell morphogenesisGO:000859410.021
response to bacteriumGO:0009617580.021
positive regulation of purine nucleotide catabolic processGO:003312310.021
regulation of cytokine productionGO:000181730.021
isoprenoid metabolic processGO:0006720150.021
multicellular organismal metabolic processGO:004423620.021
anterior posterior pattern specificationGO:00099521520.021
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.021
dna templated transcription initiationGO:000635210.021
developmental cell growthGO:0048588520.021
stem cell divisionGO:001714510.021
intracellular signal transductionGO:0035556850.020
cell cycleGO:0007049930.020
cellular response to oxygen levelsGO:007145310.020
positive regulation of cell substrate adhesionGO:001081110.020
positive regulation of apoptotic processGO:0043065290.020
centrosome duplicationGO:005129810.020
response to external stimulusGO:00096052640.020
regulation of dna replicationGO:000627530.020
positive regulation of cellular biosynthetic processGO:0031328680.020
negative regulation of kinase activityGO:003367340.020
regulation of skeletal muscle tissue developmentGO:004864140.020
mesenchyme developmentGO:00604851270.020
positive regulation of nucleoside metabolic processGO:004597910.020
regulation of cell projection assemblyGO:006049140.019
negative regulation of small gtpase mediated signal transductionGO:005105810.019
pharyngeal muscle developmentGO:004328240.019
positive regulation of nucleic acid templated transcriptionGO:1903508570.019
cell substrate adhesionGO:003158940.019
macromolecule modificationGO:00434121110.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.019
negative regulation of cell deathGO:0060548600.019
catabolic processGO:0009056320.019
purine containing compound biosynthetic processGO:0072522200.019
sexual reproductionGO:0019953360.019
positive regulation of response to stimulusGO:0048584800.019
positive regulation of immune system processGO:0002684170.019
positive regulation of neuron deathGO:190121610.019
alpha amino acid metabolic processGO:190160530.019
regulation of cell deathGO:00109411030.019
cellular response to organic substanceGO:00713101050.019
cell killingGO:000190620.019
regulation of protein transportGO:005122330.018
negative regulation of cell communicationGO:0010648960.018
response to nutrientGO:000758430.018
regulation of nucleocytoplasmic transportGO:004682220.018
leukocyte mediated immunityGO:000244360.018
regulation of autophagyGO:001050630.018
skeletal system morphogenesisGO:00487051020.018
modification dependent protein catabolic processGO:001994130.018
forebrain developmentGO:0030900960.018
negative regulation of cellular metabolic processGO:0031324770.018
cellular response to starvationGO:000926710.018
programmed cell deathGO:00125011190.018
neural crest cell developmentGO:0014032620.018
organelle assemblyGO:00709251100.018
positive regulation of neuron apoptotic processGO:004352510.018
positive regulation of leukocyte differentiationGO:190210710.018
striated muscle cell differentiationGO:00511461290.018
carbohydrate derivative biosynthetic processGO:1901137430.017
mrna 3 end processingGO:003112420.017
oogenesisGO:0048477140.017
protein sumoylationGO:001692520.017
cytoskeleton dependent cytokinesisGO:006164030.017
larval heart developmentGO:000750820.017
histone h3 k4 methylationGO:005156820.017
neuroblast proliferationGO:000740520.017
production of molecular mediator of immune responseGO:000244020.017
i kappab kinase nf kappab signalingGO:000724940.017
cell fate specificationGO:0001708680.017
negative regulation of biosynthetic processGO:0009890550.017
positive regulation of cytokine productionGO:000181920.017
regulation of reproductive processGO:200024140.017
multi organism reproductive processGO:0044703360.017
modification dependent macromolecule catabolic processGO:004363230.017
cardiac muscle tissue developmentGO:0048738480.017
meiotic cell cycle processGO:190304630.017
macromolecule localizationGO:0033036540.017
circulatory system processGO:0003013870.017
response to lipidGO:0033993600.017
cell migrationGO:00164772370.017
exocrine pancreas developmentGO:0031017280.016
sensory organ morphogenesisGO:00905962000.016
multicellular organismal homeostasisGO:0048871290.016
negative regulation of epithelial cell proliferationGO:005068010.016
regulation of hormone levelsGO:0010817210.016
mitotic dna damage checkpointGO:004477340.016
positive regulation of stress activated mapk cascadeGO:003287430.016
response to hormoneGO:0009725480.016
cell proliferationGO:0008283800.016
organelle localizationGO:0051640490.016
protein complex localizationGO:003150310.016
regulation of mitochondrion organizationGO:001082110.016
regulation of protein metabolic processGO:0051246560.016
positive regulation of histone modificationGO:003105810.016
regulation of leukocyte mediated immunityGO:000270310.016
regulation of protein targetingGO:190353320.016
cell fate commitmentGO:0045165990.016
negative regulation of muscle tissue developmentGO:190186220.016
cellular response to stressGO:0033554620.016
positive regulation of transcription dna templatedGO:0045893570.016
regulation of leukocyte mediated cytotoxicityGO:000191010.016
positive regulation of nucleobase containing compound metabolic processGO:0045935690.016
positive regulation of rna biosynthetic processGO:1902680570.016
cell agingGO:000756920.016
regulation of organelle organizationGO:0033043290.016
regulation of protein localization to nucleusGO:190018020.016
negative regulation of autophagyGO:001050710.016
negative regulation of striated muscle tissue developmentGO:004584320.016
ear developmentGO:00435831270.016
alternative mrna splicing via spliceosomeGO:000038010.016
developmental growth involved in morphogenesisGO:0060560860.016
cilium or flagellum dependent cell motilityGO:000153940.016
cellular response to radiationGO:007147840.016
lipid metabolic processGO:0006629520.016
response to topologically incorrect proteinGO:003596620.016
sex determinationGO:000753010.016
carbohydrate homeostasisGO:003350010.015
androgen metabolic processGO:000820920.015
positive regulation of ras protein signal transductionGO:004657910.015
hepaticobiliary system developmentGO:0061008980.015
skeletal muscle tissue developmentGO:0007519670.015
protein localization to plasma membraneGO:007265910.015
regulation of meiotic cell cycleGO:005144510.015
regulation of organ growthGO:004662030.015
regulation of protein bindingGO:004339330.015
negative regulation of rna biosynthetic processGO:1902679450.015
intracellular transportGO:0046907320.015
cilium movementGO:0003341260.015
autophagyGO:000691440.015
oocyte maturationGO:000155640.015
positive regulation of cell adhesionGO:004578510.015
regulation of nucleotide catabolic processGO:003081120.015
cellular response to molecule of bacterial originGO:007121930.015
negative regulation of reproductive processGO:200024230.015
response to foodGO:003209410.015
regulation of photoreceptor cell differentiationGO:004653220.015
cell cycle arrestGO:000705010.015

tbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.074
inherited metabolic disorderDOID:65500.059
cancerDOID:16200.024
disease of cellular proliferationDOID:1456600.024
organ system cancerDOID:005068600.024
endocrine gland cancerDOID:17000.024
disease of anatomical entityDOID:700.018
musculoskeletal system diseaseDOID:1700.018