Danio rerio

65 known processes

xbp1

X-box binding protein 1

(Aliases: cb918,id:ibd1195,trebf,wu:fb02h05,xbp1b,xbp1a,wu:fb63f10,treb5)

xbp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:00097922710.855
regulation of autophagyGO:001050630.695
regulation of macromolecule metabolic processGO:00602553170.694
response to organic substanceGO:00100331530.623
Human Mouse Worm Fly
regulation of transcription dna templatedGO:00063552130.617
organic substance biosynthetic processGO:19015762890.592
neuron projection developmentGO:00311751800.568
regulation of nucleic acid templated transcriptionGO:19035062130.498
cellular biosynthetic processGO:00442492860.497
regulation of cell deathGO:00109411030.494
Mouse
cellular protein catabolic processGO:004425740.439
Mouse
regulation of macromolecule biosynthetic processGO:00105562250.434
regulation of signalingGO:00230512350.389
Human
rna biosynthetic processGO:00327741810.388
cellular macromolecule biosynthetic processGO:00346452240.381
regulation of response to stimulusGO:00485832690.372
Human
proteolysis involved in cellular protein catabolic processGO:005160330.367
Mouse
lipid storageGO:001991510.352
nucleic acid templated transcriptionGO:00976591810.329
regulation of cellular metabolic processGO:00313233200.328
agingGO:000756820.321
Worm
response to stressGO:00069502630.318
Human Mouse Worm Fly
regulation of nitrogen compound metabolic processGO:00511712510.308
cell projection morphogenesisGO:00488582440.304
embryonic organ developmentGO:00485683810.291
autophagyGO:000691440.256
positive regulation of cellular processGO:00485222010.250
Human Mouse Worm Fly
organic cyclic compound metabolic processGO:19013603010.248
regulation of apoptotic processGO:0042981980.246
Mouse
nitrogen compound metabolic processGO:00068073190.243
brain developmentGO:00074202930.242
regulation of metabolic processGO:00192223590.239
collagen metabolic processGO:003296320.229
regulation of epithelial cell proliferationGO:005067830.228
Mouse
positive regulation of secretion by cellGO:190353210.217
Mouse
neuron projection morphogenesisGO:00488121610.216
macromolecule biosynthetic processGO:00090592270.215
maintenance of locationGO:005123540.210
response to biotic stimulusGO:0009607970.198
Human Mouse
negative regulation of cellular processGO:00485232830.190
Mouse
biosynthetic processGO:00090582940.185
gene expressionGO:00104672520.182
neuron developmentGO:00486662620.179
larval developmentGO:000216420.176
Worm
regulation of multicellular organismal developmentGO:20000262230.174
Human Mouse
regulation of gene expressionGO:00104682650.174
positive regulation of biological processGO:00485182530.163
Human Mouse Worm Fly
negative regulation of autophagyGO:001050710.150
regulation of multicellular organism growthGO:004001440.144
cellular nitrogen compound biosynthetic processGO:00442712180.144
single organism metabolic processGO:00447102170.143
ubiquitin dependent protein catabolic processGO:000651130.140
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.139
response to antibioticGO:004667710.131
establishment of localization in cellGO:0051649770.130
Mouse
iron ion transmembrane transportGO:003475530.129
cellular nitrogen compound metabolic processGO:00346412900.128
programmed cell deathGO:00125011190.125
Mouse
nucleobase containing compound biosynthetic processGO:00346542050.124
response to chemicalGO:00422213200.123
Human Mouse Worm Fly
multicellular organismal metabolic processGO:004423620.122
extrinsic apoptotic signaling pathwayGO:009719130.121
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.120
positive regulation of cell deathGO:0010942290.119
response to nutrientGO:000758430.117
cell deathGO:00082191210.114
Mouse
viral processGO:001603210.111
head developmentGO:00603223030.111
generation of neuronsGO:00486993850.110
embryonic organ morphogenesisGO:00485622740.105
signal transductionGO:00071654550.105
Human Mouse Worm Fly
transcription dna templatedGO:00063511810.103
cell agingGO:000756920.102
negative regulation of biological processGO:00485193040.102
Mouse
regulation of biosynthetic processGO:00098892500.102
regulation of cell communicationGO:00106462320.100
Human
nucleic acid metabolic processGO:00903042440.099
negative regulation of epithelial cell proliferationGO:005068010.099
proteasomal protein catabolic processGO:001049820.099
Mouse
regulation of protein metabolic processGO:0051246560.098
Mouse
male meiosisGO:000714020.098
response to external stimulusGO:00096052640.095
Human Mouse
cell projection organizationGO:00300302840.092
regulation of response to nutrient levelsGO:003210710.090
cellular component morphogenesisGO:00329893360.090
chromatin modificationGO:0016568210.089
symbiosis encompassing mutualism through parasitismGO:004440340.088
homeostatic processGO:00425921420.088
Mouse
cell morphogenesisGO:00009022890.087
blood circulationGO:0008015870.083
multi organism cellular processGO:004476420.082
cellular response to starvationGO:000926710.079
regulation of rna metabolic processGO:00512522240.075
regulation of cellular macromolecule biosynthetic processGO:20001122220.074
establishment of protein localization to organelleGO:007259440.073
response to inorganic substanceGO:0010035380.073
interaction with hostGO:005170140.073
tube morphogenesisGO:00352393490.073
multicellular organism growthGO:003526440.073
glycoprotein metabolic processGO:0009100230.071
negative regulation of cell deathGO:0060548600.071
Mouse
cellular response to extracellular stimulusGO:003166820.070
modification dependent protein catabolic processGO:001994130.070
organelle organizationGO:00069962270.068
cellular response to chemical stimulusGO:00708871570.068
Human Mouse Worm Fly
heterocycle metabolic processGO:00464832900.068
chordate embryonic developmentGO:00430092710.066
chromosome organizationGO:0051276310.066
response to transition metal nanoparticleGO:1990267280.066
water homeostasisGO:003010440.065
organic acid metabolic processGO:0006082310.064
nucleobase containing compound metabolic processGO:00061392740.063
regulation of response to extracellular stimulusGO:003210410.063
heterocycle biosynthetic processGO:00181302150.063
cellular response to nutrient levelsGO:003166920.062
multicellular organismal macromolecule metabolic processGO:004425920.062
central nervous system developmentGO:00074173870.062
single organism biosynthetic processGO:0044711710.061
protein targeting to membraneGO:000661210.061
cellular response to external stimulusGO:007149620.061
single organism localizationGO:19025782250.061
Mouse
positive regulation of multicellular organismal processGO:0051240520.061
Human Mouse
carboxylic acid metabolic processGO:0019752220.060
digestive system developmentGO:00551232890.060
Mouse
regionalizationGO:00030022740.060
positive regulation of transportGO:005105020.060
Mouse
protein glycosylationGO:000648690.060
immune system processGO:00023762410.060
Human Mouse
forebrain developmentGO:0030900960.060
mesenchyme developmentGO:00604851270.059
positive regulation of biosynthetic processGO:0009891680.059
Human Mouse Worm Fly
diterpenoid metabolic processGO:0016101150.058
cellular respirationGO:004533330.057
response to estrogenGO:0043627270.057
sensory organ developmentGO:00074233930.057
Fly
embryonic skeletal system developmentGO:0048706970.057
skeletal system developmentGO:00015011810.056
carbohydrate homeostasisGO:003350010.056
Mouse
apoptotic processGO:00069151160.055
Mouse
regulation of rna biosynthetic processGO:20011412130.055
regulation of developmental processGO:00507932470.055
Human Mouse
muscle structure developmentGO:00610611960.055
regulation of programmed cell deathGO:00430671010.053
Mouse
aromatic compound biosynthetic processGO:00194382170.053
appendage developmentGO:0048736800.052
connective tissue developmentGO:0061448990.051
dopaminergic neuron differentiationGO:0071542140.051
embryonic cranial skeleton morphogenesisGO:0048701900.051
interspecies interaction between organismsGO:004441940.050
cell part morphogenesisGO:00329902460.050
regulation of multicellular organismal processGO:00512392770.050
Human Mouse
response to external biotic stimulusGO:0043207970.049
Human Mouse
protein acylationGO:004354330.047
regulation of cellular ketone metabolic processGO:001056570.047
protein metabolic processGO:00195381830.046
Mouse
regulation of signal transductionGO:00099662250.046
Human
regulation of epidermis developmentGO:004568220.046
positive regulation of secretionGO:005104710.045
Mouse
response to organic cyclic compoundGO:0014070510.045
axon developmentGO:00615641660.045
cellular response to estrogen stimulusGO:0071391240.045
negative regulation of protein kinase activityGO:000646940.043
positive regulation of translationGO:004572710.043
macromolecule localizationGO:0033036540.043
Mouse
cellular macromolecule metabolic processGO:00442603910.043
positive regulation of programmed cell deathGO:0043068290.041
deathGO:00162651210.041
Mouse
covalent chromatin modificationGO:0016569200.041
response to amino acidGO:004320020.041
positive regulation of cellular metabolic processGO:0031325940.040
Human Mouse Worm Fly
photoreceptor cell differentiationGO:0046530550.040
regulation of nucleobase containing compound metabolic processGO:00192192500.039
cell surface receptor signaling pathwayGO:00071663250.039
organic cyclic compound biosynthetic processGO:19013622230.039
heart developmentGO:00075073130.039
cranial nerve developmentGO:0021545420.039
sister chromatid cohesionGO:000706220.038
regulation of primary metabolic processGO:00800903110.038
rna metabolic processGO:00160702190.037
cellular response to topologically incorrect proteinGO:003596720.037
Human Mouse Worm Fly
hormone transportGO:000991420.037
positive regulation of apoptotic signaling pathwayGO:200123510.036
locomotionGO:00400113130.036
Worm
protein modification processGO:00362111000.036
cellular catabolic processGO:0044248270.035
Mouse
hemopoiesisGO:00300971830.035
Human
intracellular transportGO:0046907320.035
ceramide biosynthetic processGO:004651310.034
ear developmentGO:00435831270.034
positive regulation of macromolecule metabolic processGO:0010604930.034
Human Mouse Worm Fly
negative regulation of kinase activityGO:003367340.033
purine nucleotide metabolic processGO:0006163270.033
response to abiotic stimulusGO:00096281220.033
central nervous system neuron developmentGO:0021954290.033
regulation of protein ubiquitinationGO:003139630.033
hindbrain developmentGO:0030902910.033
cellular response to radiationGO:007147840.032
positive regulation of cellular amino acid metabolic processGO:004576400.032
regulation of nucleotide catabolic processGO:003081120.031
neurological system processGO:0050877620.031
cellular protein metabolic processGO:00442671290.031
Mouse
cellular response to stressGO:0033554620.031
Human Mouse Worm Fly
digestive tract morphogenesisGO:00485462310.031
cellular protein modification processGO:00064641000.031
positive regulation of neuron deathGO:190121610.031
regulation of bindingGO:005109830.030
response to hormoneGO:0009725480.030
central nervous system myelinationGO:002201020.030
single organism transportGO:00447652060.030
Mouse
oxoacid metabolic processGO:0043436310.030
response to cadmium ionGO:0046686140.030
appendage morphogenesisGO:0035107560.030
cellular amino acid biosynthetic processGO:000865220.029
positive regulation of multi organism processGO:004390230.029
regulation of hormone secretionGO:004688320.029
macromolecule modificationGO:00434121110.029
macromolecule glycosylationGO:004341390.029
epithalamus developmentGO:0021538100.029
response to endogenous stimulusGO:0009719830.029
cartilage developmentGO:0051216960.028
regulation of blood vessel sizeGO:005088020.028
vitamin biosynthetic processGO:000911020.028
single organism organelle organizationGO:19025891990.028
regulation of establishment or maintenance of cell polarityGO:003287820.028
positive regulation of metabolic processGO:00098931080.028
Human Mouse Worm Fly
intracellular signal transductionGO:0035556850.027
cell cycleGO:0007049930.027
negative regulation of cellular catabolic processGO:003133030.026
reflexGO:006000420.026
response to virusGO:0009615210.025
regulation of gtp catabolic processGO:003312420.025
intra s dna damage checkpointGO:003157310.025
regulation of cytokine productionGO:000181730.025
Mouse
response to lipidGO:0033993600.025
Human Mouse
cellular response to organic substanceGO:00713101050.024
Human Mouse Worm Fly
striated muscle cell differentiationGO:00511461290.024
negative regulation of programmed cell deathGO:0043069580.024
Mouse
negative regulation of neuron projection regenerationGO:007057140.023
gtp metabolic processGO:004603940.023
meiotic cell cycle processGO:190304630.023
cartilage condensationGO:000150230.023
neuron differentiationGO:00301823530.023
response to steroid hormoneGO:0048545350.023
meiotic chromosome segregationGO:004513230.023
response to metal ionGO:0010038340.023
cellular macromolecule catabolic processGO:0044265120.022
Mouse
negative regulation of signal transduction by p53 class mediatorGO:190179780.022
regulation of gtpase activityGO:004308720.022
regulation of biological qualityGO:00650082630.022
Mouse
negative regulation of metabolic processGO:0009892860.022
peptidyl serine modificationGO:001820920.022
response to extracellular stimulusGO:0009991100.022
negative regulation of rna metabolic processGO:0051253480.022
spermatid developmentGO:000728620.022
p38mapk cascadeGO:003806610.022
modification dependent macromolecule catabolic processGO:004363230.021
protein o linked glycosylationGO:000649340.021
internal peptidyl lysine acetylationGO:001839320.021
response to corticosteroidGO:003196010.021
negative regulation of catabolic processGO:000989530.021
response to uvGO:000941130.021
organelle localizationGO:0051640490.020
response to temperature stimulusGO:0009266150.020
regulation of cell substrate adhesionGO:001081010.020
organonitrogen compound metabolic processGO:1901564740.020
protein localization to nucleusGO:003450430.020
myeloid cell differentiationGO:0030099860.020
regulation of neurogenesisGO:0050767870.020
regulation of cellular biosynthetic processGO:00313262450.019
cellular ketone metabolic processGO:0042180110.019
positive regulation of apoptotic processGO:0043065290.019
gastrulationGO:00073692080.019
mesenchymal cell differentiationGO:0048762870.019
meiotic nuclear divisionGO:000712640.019
macroautophagyGO:001623610.019
regulation of protein modification by small protein conjugation or removalGO:190332030.019
melanin metabolic processGO:000658220.019
developmental growthGO:00485891660.019
response to hexoseGO:000974630.019
response to woundingGO:00096111160.018
specification of symmetryGO:00097992040.018
cellular amine metabolic processGO:004410620.018
endocardial cushion formationGO:000327220.018
internal protein amino acid acetylationGO:000647520.018
retina homeostasisGO:0001895120.018
response to growth factorGO:0070848390.018
positive regulation of epithelial cell proliferationGO:005067910.018
Mouse
cell morphogenesis involved in neuron differentiationGO:00486671630.018
cell matrix adhesionGO:000716040.018
ceramide metabolic processGO:000667250.017
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.017
guanosine containing compound catabolic processGO:190106920.017
gland developmentGO:00487321430.017
positive regulation of wound healingGO:009030310.017
erythrocyte homeostasisGO:0034101550.017
protein acetylationGO:000647320.017
cell substrate junction assemblyGO:000704420.017
regulation of molecular functionGO:0065009700.016
membrane invaginationGO:001032410.016
regulation of cellular protein metabolic processGO:0032268520.016
Mouse
positive regulation of nitrogen compound metabolic processGO:0051173690.016
Human Mouse Worm Fly
establishment of melanosome localizationGO:0032401190.016
ectoderm formationGO:000170520.016
proteolysisGO:0006508380.016
Mouse
mannosylationGO:009750230.016
cellular modified amino acid metabolic processGO:000657530.016
guanosine containing compound metabolic processGO:190106840.015
axial mesoderm structural organizationGO:004833120.015
embryonic limb morphogenesisGO:003032620.015
anatomical structure arrangementGO:004853220.015
regulation of neuron differentiationGO:0045664560.015
system processGO:00030081850.015
cellular response to lipopolysaccharideGO:007122230.015
Human Mouse
pigmentationGO:0043473850.015
single organism cellular localizationGO:1902580460.015
lateral line ganglion developmentGO:004889020.015
regulation of nucleocytoplasmic transportGO:004682220.015
positive regulation of cellular biosynthetic processGO:0031328680.015
Human Mouse Worm Fly
intestinal epithelial cell differentiationGO:006057530.015
morphogenesis of an epitheliumGO:00020093330.015
fin developmentGO:0033333770.015
nerve developmentGO:0021675450.015
negative regulation of protein phosphorylationGO:000193340.015
single organism intracellular transportGO:1902582250.014
regulation of purine nucleotide catabolic processGO:003312120.014
growthGO:00400071740.014
regulation of water loss via skinGO:003356110.014
positive regulation of cellular component biogenesisGO:004408930.014
glycosylationGO:0070085110.014
cellular protein localizationGO:0034613200.014
wnt signaling pathwayGO:0016055800.014
habenula developmentGO:002198690.014
establishment of organelle localizationGO:0051656450.014
response to glucoseGO:000974930.014
establishment of localizationGO:00512342440.014
Mouse
axon ensheathment in central nervous systemGO:003229120.014
negative regulation of signal transduction in absence of ligandGO:190109910.014
cellular macromolecule localizationGO:0070727210.014
regulation of intracellular signal transductionGO:1902531570.014
multicellular organismal water homeostasisGO:005089110.014
hormone secretionGO:004687920.014
glucose homeostasisGO:004259310.013
Mouse
response to radiationGO:0009314510.013
positive regulation of transcription dna templatedGO:0045893570.013
Human Mouse Worm Fly
ion transportGO:00068111140.013
isoprenoid metabolic processGO:0006720150.013
cellular response to organic cyclic compoundGO:0071407380.013
cellular response to oxygen containing compoundGO:1901701200.013
Human Mouse
regulation of nucleoside metabolic processGO:000911820.013
negative regulation of apoptotic processGO:0043066550.013
Mouse
positive regulation of neuron apoptotic processGO:004352510.013
protein destabilizationGO:003164810.013
cellular aldehyde metabolic processGO:000608140.013
cytokinetic processGO:003250620.013
cellular response to steroid hormone stimulusGO:0071383310.013
multicellular organismal response to stressGO:003355520.013
cellular response to interferon gammaGO:007134610.013
sensory organ morphogenesisGO:00905962000.013
formation of primary germ layerGO:0001704620.013
centrosome cycleGO:000709810.013
multi organism processGO:00517041340.013
Human Mouse
chromatin organizationGO:0006325220.013
positive regulation of nucleobase containing compound metabolic processGO:0045935690.012
Human Mouse Worm Fly
secondary metabolic processGO:001974830.012
fat soluble vitamin biosynthetic processGO:004236220.012
response to carbohydrateGO:000974330.012
peptidyl lysine acetylationGO:001839420.012
positive regulation of epithelial cell differentiationGO:003085820.012
reciprocal meiotic recombinationGO:000713110.012
innate immune responseGO:0045087130.012
hatching gland developmentGO:004878530.012
positive regulation of chromatin modificationGO:190331010.012
inner ear developmentGO:00488391260.012
photoreceptor cell developmentGO:0042461400.012
positive regulation of histone deacetylationGO:003106510.012
regulation of extrinsic apoptotic signaling pathwayGO:200123630.012
protein importGO:001703830.012
positive regulation of catabolic processGO:000989640.012
Mouse
regulation of microtubule based movementGO:006063230.012
iron ion transportGO:000682640.012
single organism carbohydrate metabolic processGO:0044723120.012
regulation of establishment of protein localizationGO:007020140.012
Mouse
steroid metabolic processGO:000820270.012
epithelial cell morphogenesisGO:000338220.012
positive regulation of gene expressionGO:0010628710.012
Human Mouse Worm Fly
embryonic skeletal system morphogenesisGO:0048704930.012
regulation of alcohol biosynthetic processGO:190293010.012
cellular response to virusGO:009858610.011
i kappab kinase nf kappab signalingGO:000724940.011
cellular response to hormone stimulusGO:0032870390.011
organism emergence from protective structureGO:007168440.011
small molecule metabolic processGO:0044281770.011
camera type eye morphogenesisGO:00485931080.011
cellular amino acid metabolic processGO:000652070.011
endocardial cushion morphogenesisGO:000320330.011
regulation of dna templated transcription in response to stressGO:004362000.011
regulation of developmental growthGO:0048638380.011
cellular aromatic compound metabolic processGO:00067252950.011
negative regulation of cytoplasmic transportGO:190365020.011
endocardium morphogenesisGO:000316040.011
peptide transportGO:001583310.011
neural crest cell differentiationGO:0014033720.011
negative regulation of multi organism processGO:004390130.011
extracellular matrix organizationGO:0030198270.011
er nucleus signaling pathwayGO:000698420.011
Human Mouse Worm Fly
adult behaviorGO:003053420.011
regulation of photoreceptor cell differentiationGO:004653220.011
regulation of tube sizeGO:003515020.011
regulation of intracellular protein transportGO:003315730.011
chromosome organization involved in meiosisGO:007019210.011
positive regulation of cellular amine metabolic processGO:003324000.010
regulation of transcription from rna polymerase ii promoterGO:00063571140.010
cellular response to toxic substanceGO:009723710.010
transportGO:00068102200.010
Mouse
organic substance catabolic processGO:1901575280.010
Mouse
negative regulation of nucleic acid templated transcriptionGO:1903507450.010
negative regulation of intracellular protein transportGO:009031730.010
collagen biosynthetic processGO:003296420.010
cell aggregationGO:009874330.010
skeletal system morphogenesisGO:00487051020.010
nuclear importGO:005117030.010
transmembrane transportGO:00550851200.010
small gtpase mediated signal transductionGO:000726480.010
cellular response to endogenous stimulusGO:0071495680.010
cellular amide metabolic processGO:004360340.010

xbp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.079
disease of cellular proliferationDOID:1456600.079
organ system cancerDOID:005068600.079
integumentary system diseaseDOID:1600.027
disease of anatomical entityDOID:700.027
breast cancerDOID:161200.015
thoracic cancerDOID:509300.015
musculoskeletal system diseaseDOID:1700.014