Danio rerio

0 known processes

hpse

heparanase

(Aliases: im:7144134)

hpse biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval developmentGO:000216420.060
endosomal transportGO:001619720.052
phagocytosisGO:000690930.050
agingGO:000756820.049
guanosine containing compound metabolic processGO:190106840.048
cytokinesisGO:000091030.044
positive regulation of catabolic processGO:000989640.044
single organism membrane fusionGO:004480120.043
guanosine containing compound catabolic processGO:190106920.043
gtp metabolic processGO:004603940.043
cellular response to external stimulusGO:007149620.041
multicellular organism growthGO:003526440.041
positive regulation of cellular component biogenesisGO:004408930.041
autophagyGO:000691440.040
positive regulation of transportGO:005105020.040
regulation of protein complex assemblyGO:004325430.040
amine metabolic processGO:000930820.040
nitrogen compound metabolic processGO:00068073190.039
positive regulation of cell cycleGO:004578730.039
cellular amine metabolic processGO:004410620.038
organelle fusionGO:004828430.038
gtp catabolic processGO:000618420.038
positive regulation of cellular catabolic processGO:003133130.038
establishment of protein localization to organelleGO:007259440.038
cellular macromolecule metabolic processGO:00442603910.038
regulation of bindingGO:005109830.036
maintenance of locationGO:005123540.036
golgi vesicle transportGO:004819330.035
regulation of nitrogen compound metabolic processGO:00511712510.034
cellular biosynthetic processGO:00442492860.034
membrane fusionGO:006102520.033
cellular protein catabolic processGO:004425740.033
heterocycle metabolic processGO:00464832900.033
cellular response to extracellular stimulusGO:003166820.033
signal transductionGO:00071654550.032
nucleobase containing compound metabolic processGO:00061392740.032
synaptic vesicle localizationGO:009747910.032
cellular nitrogen compound metabolic processGO:00346412900.031
ubiquitin dependent protein catabolic processGO:000651130.031
cellular response to nutrient levelsGO:003166920.031
organonitrogen compound metabolic processGO:1901564740.030
cellular amino acid metabolic processGO:000652070.030
generation of neuronsGO:00486993850.029
modification dependent macromolecule catabolic processGO:004363230.029
proteolysis involved in cellular protein catabolic processGO:005160330.029
regulation of synaptic plasticityGO:004816710.029
regulation of cellular amine metabolic processGO:003323800.029
regulation of cellular amino acid metabolic processGO:000652100.029
vasculature developmentGO:00019442780.029
peptidyl serine phosphorylationGO:001810510.029
cell projection organizationGO:00300302840.028
regulation of cellular ketone metabolic processGO:001056570.028
proteasomal protein catabolic processGO:001049820.028
protein localization to plasma membraneGO:007265910.028
protein polymerizationGO:005125840.028
positive regulation of secretion by cellGO:190353210.027
regulation of protein catabolic processGO:004217610.027
small molecule metabolic processGO:0044281770.027
regulation of cellular metabolic processGO:00313233200.027
oxoacid metabolic processGO:0043436310.027
regulation of cell shapeGO:000836010.027
negative regulation of biological processGO:00485193040.027
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.027
cellular response to starvationGO:000926710.027
response to drugGO:004249330.027
meiotic cell cycle processGO:190304630.026
regulation of metabolic processGO:00192223590.026
neuron differentiationGO:00301823530.026
regulation of protein transportGO:005122330.026
mitochondrion organizationGO:000700540.026
liver developmentGO:0001889960.026
meiotic nuclear divisionGO:000712640.026
modification dependent protein catabolic processGO:001994130.025
regulation of establishment of protein localizationGO:007020140.025
biosynthetic processGO:00090582940.025
synaptic vesicle transportGO:004848910.025
cellular ketone metabolic processGO:0042180110.025
response to chemicalGO:00422213200.025
regulation of biological qualityGO:00650082630.025
embryonic organ developmentGO:00485683810.025
establishment of localizationGO:00512342440.025
organic cyclic compound metabolic processGO:19013603010.024
stem cell proliferationGO:007208940.024
regulation of cell communicationGO:00106462320.024
single organism localizationGO:19025782250.024
lipid storageGO:001991510.023
regulation of nucleobase containing compound metabolic processGO:00192192500.023
regulation of gtp catabolic processGO:003312420.023
cellular aromatic compound metabolic processGO:00067252950.023
negative regulation of cellular processGO:00485232830.023
neuron developmentGO:00486662620.023
regulation of nucleoside metabolic processGO:000911820.023
gland developmentGO:00487321430.023
single organism transportGO:00447652060.023
regulation of multicellular organism growthGO:004001440.023
stem cell maintenanceGO:001982740.023
cellular component morphogenesisGO:00329893360.023
response to alkaloidGO:004327920.022
positive regulation of biological processGO:00485182530.022
cognitionGO:005089010.022
carboxylic acid metabolic processGO:0019752220.022
actin polymerization or depolymerizationGO:000815420.022
regulation of protein polymerizationGO:003227120.022
organic acid metabolic processGO:0006082310.022
establishment of protein localization to plasma membraneGO:009000210.022
regulation of purine nucleotide catabolic processGO:003312120.022
gene expressionGO:00104672520.021
cellular component movementGO:00069283350.021
brain developmentGO:00074202930.021
single organism metabolic processGO:00447102170.021
peptidyl serine modificationGO:001820920.021
regulation of multicellular organismal processGO:00512392770.021
protein dephosphorylationGO:000647030.021
regulation of cytokine productionGO:000181730.021
protein importGO:001703830.021
regulation of response to stimulusGO:00485832690.021
regulation of wound healingGO:006104120.020
hepaticobiliary system developmentGO:0061008980.020
establishment of synaptic vesicle localizationGO:009748010.020
positive regulation of cellular amine metabolic processGO:003324000.020
nucleic acid templated transcriptionGO:00976591810.020
system processGO:00030081850.020
positive regulation of protein complex assemblyGO:003133420.020
phagocytosis engulfmentGO:000691110.020
regulation of macromolecule metabolic processGO:00602553170.020
macromolecule biosynthetic processGO:00090592270.020
regulation of autophagyGO:001050630.020
heart developmentGO:00075073130.020
regulation of primary metabolic processGO:00800903110.020
rna metabolic processGO:00160702190.020
exocytosisGO:000688710.020
neuron projection morphogenesisGO:00488121610.020
chordate embryonic developmentGO:00430092710.020
macroautophagyGO:001623610.020
stem cell divisionGO:001714510.020
positive regulation of secretionGO:005104710.020
protein secretionGO:000930610.020
cell projection morphogenesisGO:00488582440.020
regulation of gtpase activityGO:004308720.020
neuroblast proliferationGO:000740520.020
cellular component disassemblyGO:002241110.020
regulation of biosynthetic processGO:00098892500.019
cell part morphogenesisGO:00329902460.019
positive regulation of stress activated mapk cascadeGO:003287430.019
regulation of nucleotide catabolic processGO:003081120.019
regulation of signalingGO:00230512350.019
embryonic organ morphogenesisGO:00485622740.019
response to stressGO:00069502630.019
nuclear transportGO:005116940.019
nucleic acid metabolic processGO:00903042440.019
positive regulation of cytoskeleton organizationGO:005149530.019
response to external stimulusGO:00096052640.019
regulation of cellular biosynthetic processGO:00313262450.019
transportGO:00068102200.018
immune system processGO:00023762410.018
cellular amide metabolic processGO:004360340.018
cytoskeleton dependent cytokinesisGO:006164030.018
extrinsic apoptotic signaling pathwayGO:009719130.018
blood vessel developmentGO:00015682460.018
nucleocytoplasmic transportGO:000691340.018
positive regulation of cellular processGO:00485222010.018
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.018
cellular nitrogen compound biosynthetic processGO:00442712180.018
regulation of intracellular protein transportGO:003315730.018
positive regulation of cytokine productionGO:000181920.018
post golgi vesicle mediated transportGO:000689210.018
regulation of synapse organizationGO:005080730.018
regulation of cytoplasmic transportGO:190364940.018
centrosome organizationGO:005129710.018
microtubule organizing center organizationGO:003102310.017
cellular component biogenesisGO:00440851780.017
cell substrate adhesionGO:003158940.017
central nervous system developmentGO:00074173870.017
regulation of protein modification by small protein conjugation or removalGO:190332030.017
organic substance biosynthetic processGO:19015762890.017
negative regulation of protein complex assemblyGO:003133310.017
cellular macromolecule biosynthetic processGO:00346452240.017
rna biosynthetic processGO:00327741810.017
regulation of gene expressionGO:00104682650.017
response to hydrogen peroxideGO:004254230.017
tube morphogenesisGO:00352393490.017
positive regulation of cell adhesionGO:004578510.017
cell motilityGO:00488702440.017
macromolecular complex disassemblyGO:003298410.017
cellular carbohydrate metabolic processGO:004426240.017
cellular protein metabolic processGO:00442671290.017
cell surface receptor signaling pathwayGO:00071663250.017
positive regulation of map kinase activityGO:004340630.017
positive regulation of gtpase activityGO:004354710.017
organic cyclic compound biosynthetic processGO:19013622230.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
regulation of synapse assemblyGO:005196330.016
g2 m transition of mitotic cell cycleGO:000008640.016
membrane invaginationGO:001032410.016
protein complex disassemblyGO:004324110.016
response to topologically incorrect proteinGO:003596620.016
morphogenesis of an epitheliumGO:00020093330.016
positive regulation of nucleotide catabolic processGO:003081310.016
regulation of macromolecule biosynthetic processGO:00105562250.016
head developmentGO:00603223030.016
regulation of synaptic growth at neuromuscular junctionGO:000858210.016
determination of left right symmetryGO:00073681790.016
nuclear importGO:005117030.016
internal protein amino acid acetylationGO:000647520.016
cellular protein modification processGO:00064641000.016
cell morphogenesisGO:00009022890.016
negative regulation of protein phosphorylationGO:000193340.016
protein metabolic processGO:00195381830.016
spermatid developmentGO:000728620.016
regulation of transcription dna templatedGO:00063552130.016
double strand break repairGO:000630230.016
homeostatic processGO:00425921420.016
regulation of developmental processGO:00507932470.016
positive regulation of nitrogen compound metabolic processGO:0051173690.016
cell deathGO:00082191210.015
organelle organizationGO:00069962270.015
cell migrationGO:00164772370.015
production of molecular mediator of immune responseGO:000244020.015
blood vessel morphogenesisGO:00485142160.015
regulation of nucleic acid templated transcriptionGO:19035062130.015
apoptotic processGO:00069151160.015
regulation of cell substrate adhesionGO:001081010.015
determination of bilateral symmetryGO:00098552040.015
response to uvGO:000941130.015
cellular response to biotic stimulusGO:007121630.015
regulation of circadian rhythmGO:004275240.015
regulation of metal ion transportGO:001095940.015
regulation of rna metabolic processGO:00512522240.015
chemosensory behaviorGO:000763510.015
neurotransmitter secretionGO:000726920.015
deathGO:00162651210.015
compound eye developmentGO:004874920.015
single organism organelle organizationGO:19025891990.015
regulation of rna biosynthetic processGO:20011412130.015
neuron projection developmentGO:00311751800.015
response to carbohydrateGO:000974330.015
actin filament polymerizationGO:003004120.015
protein polyubiquitinationGO:000020940.015
specification of symmetryGO:00097992040.015
response to external biotic stimulusGO:0043207970.015
transcription dna templatedGO:00063511810.015
tissue remodelingGO:004877140.015
positive regulation of purine nucleotide catabolic processGO:003312310.015
regulation of protein targetingGO:190353320.015
axon developmentGO:00615641660.015
carbohydrate homeostasisGO:003350010.015
positive regulation of dna metabolic processGO:005105410.015
regulation of protein bindingGO:004339330.015
negative regulation of catabolic processGO:000989530.015
regulation of protein localization to nucleusGO:190018020.015
protein acetylationGO:000647320.015
cellular response to chemical stimulusGO:00708871570.015
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.015
regulation of protein ubiquitinationGO:003139630.015
regulation of cellular carbohydrate metabolic processGO:001067540.014
synaptic growth at neuromuscular junctionGO:005112420.014
adult behaviorGO:003053420.014
axonogenesisGO:00074091520.014
protein targeting to nucleusGO:004474430.014
protein acylationGO:004354330.014
golgi organizationGO:000703010.014
protein localization to nucleusGO:003450430.014
nucleobase containing compound biosynthetic processGO:00346542050.014
regulation of programmed cell deathGO:00430671010.014
single organism nuclear importGO:190259330.014
positive regulation of nucleoside metabolic processGO:004597910.014
locomotionGO:00400113130.014
neuron neuron synaptic transmissionGO:000727010.014
regulation of cell projection assemblyGO:006049140.014
cortical actin cytoskeleton organizationGO:003086610.014
regulation of anatomical structure morphogenesisGO:00226031300.014
regulation of stem cell proliferationGO:007209120.014
digestive tract morphogenesisGO:00485462310.014
cellular component assemblyGO:00226071700.014
regulation of protein import into nucleusGO:004230620.014
regulation of meiotic cell cycleGO:005144510.014
sequestering of metal ionGO:005123830.014
regulation of carbohydrate metabolic processGO:000610940.014
locomotor rhythmGO:004547530.014
regulation of nucleocytoplasmic transportGO:004682220.014
regulation of transporter activityGO:003240920.014
regulation of cellular macromolecule biosynthetic processGO:20001122220.014
regulation of cell activationGO:005086510.014
negative regulation of sequestering of calcium ionGO:005128340.014
regulation of multicellular organismal developmentGO:20000262230.014
protein import into nucleusGO:000660630.014
regulation of mrna processingGO:005068430.013
meiotic chromosome segregationGO:004513230.013
peptide transportGO:001583310.013
positive regulation of cell activationGO:005086710.013
regulation of i kappab kinase nf kappab signalingGO:004312240.013
lamellipodium assemblyGO:003003210.013
microtubule based movementGO:0007018330.013
phosphate containing compound metabolic processGO:00067961080.013
symbiosis encompassing mutualism through parasitismGO:004440340.013
response to nutrientGO:000758430.013
peptidyl lysine acetylationGO:001839420.013
regulation of filopodium assemblyGO:005148920.013
localization of cellGO:00516742440.013
embryo development ending in birth or egg hatchingGO:00097922710.013
alcohol biosynthetic processGO:004616520.013
growthGO:00400071740.013
regulation of response to biotic stimulusGO:000283120.013
macromolecule modificationGO:00434121110.013
vacuolar transportGO:000703420.013
response to other organismGO:0051707970.013
regulation of reproductive processGO:200024140.013
heterocycle biosynthetic processGO:00181302150.013
regulation of microtubule cytoskeleton organizationGO:007050730.013
neurotransmitter transportGO:000683620.013
actin filament based movementGO:003004810.013
cortical cytoskeleton organizationGO:003086510.013
secondary metabolic processGO:001974830.013
aromatic compound biosynthetic processGO:00194382170.013
lamellipodium organizationGO:009758110.013
digestive tract developmentGO:00485652650.013
regulation of signal transductionGO:00099662250.013
angiogenesisGO:00015251580.013
g1 s transition of mitotic cell cycleGO:000008210.013
positive regulation of jnk cascadeGO:004633030.013
regulation of cell deathGO:00109411030.013
positive regulation of gtp catabolic processGO:003312610.013
regulation of reactive oxygen species metabolic processGO:200037720.012
negative regulation of cellular catabolic processGO:003133030.012
i kappab kinase nf kappab signalingGO:000724940.012
regulation of alternative mrna splicing via spliceosomeGO:000038110.012
negative regulation of protein kinase activityGO:000646940.012
gastrulationGO:00073692080.012
protein modification processGO:00362111000.012
negative regulation of kinase activityGO:003367340.012
spermatid differentiationGO:004851520.012
regulation of exocytosisGO:001715710.012
glucose homeostasisGO:004259310.012
digestive system developmentGO:00551232890.012
cellular response to radiationGO:007147840.012
regionalizationGO:00030022740.012
alternative mrna splicing via spliceosomeGO:000038010.012
programmed cell deathGO:00125011190.012
sensory organ developmentGO:00074233930.012
regulation of apoptotic processGO:0042981980.012
cell cycle g2 m phase transitionGO:004483940.012
regulation of cellular component organizationGO:0051128860.012
cytoplasm organizationGO:000702840.012
antimicrobial humoral responseGO:001973020.012
regulation of mrna splicing via spliceosomeGO:004802430.012
synaptic vesicle recyclingGO:003646510.012
transcription from rna polymerase ii promoterGO:0006366800.012
cellular response to molecule of bacterial originGO:007121930.012
transmembrane transportGO:00550851200.012
regulation of cellular protein catabolic processGO:190336210.012
multi organism processGO:00517041340.012
negative regulation of protein transportGO:005122430.012
mitotic cytokinesisGO:000028130.012
neurological system processGO:0050877620.012
centrosome cycleGO:000709810.012
ribonucleoside monophosphate catabolic processGO:000915840.012
cell matrix adhesionGO:000716040.012
inner ear developmentGO:00488391260.012
response to organic substanceGO:00100331530.012
internal peptidyl lysine acetylationGO:001839320.012
small molecule catabolic processGO:004428230.011
developmental growthGO:00485891660.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
cellular response to reactive oxygen speciesGO:003461420.011
response to monosaccharideGO:003428430.011
interspecies interaction between organismsGO:004441940.011
regulation of phGO:000688530.011
regulation of cell developmentGO:00602841000.011
translational initiationGO:000641330.011
regulation of neural precursor cell proliferationGO:200017730.011
cellular response to topologically incorrect proteinGO:003596720.011
positive regulation of wound healingGO:009030310.011
regulation of transmembrane transporter activityGO:002289820.011
positive regulation of cytosolic calcium ion concentrationGO:000720440.011
regulation of rho protein signal transductionGO:003502320.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
negative regulation of cytokine productionGO:000181810.011
activation of mapk activityGO:000018730.011
regulation of sequestering of calcium ionGO:005128240.011
rna localizationGO:000640340.011
regulation of jak stat cascadeGO:004642530.011
lipid catabolic processGO:001604240.011
regulation of organelle assemblyGO:190211540.011
sequestering of calcium ionGO:005120830.011
fertilizationGO:000956630.011
regulation of calcium ion transportGO:005192420.011
organelle localizationGO:0051640490.011
cellular localizationGO:0051641970.011
response to unfolded proteinGO:000698620.011
nucleic acid transportGO:005065720.011
negative regulation of nitrogen compound metabolic processGO:0051172590.011
epithelial tube morphogenesisGO:00605621480.011
regulation of ras gtpase activityGO:003231820.011
response to biotic stimulusGO:0009607970.011
cell morphogenesis involved in neuron differentiationGO:00486671630.011
negative regulation of intracellular transportGO:003238730.011
protein targeting to membraneGO:000661210.011
cytosolic calcium ion transportGO:006040130.011
oocyte anterior posterior axis specificationGO:000731440.011
cell morphogenesis involved in differentiationGO:00009041950.011
female sex differentiationGO:004666040.010
regulation of protein complex disassemblyGO:004324410.010
ion transmembrane transportGO:0034220910.010
negative regulation of multi organism processGO:004390130.010
melanin metabolic processGO:000658220.010
adherens junction organizationGO:003433240.010
development of primary female sexual characteristicsGO:004654540.010
neuromuscular synaptic transmissionGO:000727420.010
cellular response to light stimulusGO:007148240.010
negative regulation of response to stimulusGO:00485851040.010
leukocyte proliferationGO:007066110.010
nuclear migrationGO:000709730.010
endosome organizationGO:000703220.010
regulation of symbiosis encompassing mutualism through parasitismGO:004390310.010
positive regulation of protein polymerizationGO:003227320.010
carbohydrate biosynthetic processGO:001605110.010
synaptic vesicle endocytosisGO:004848810.010
negative regulation of cytoplasmic transportGO:190365020.010
regulation of inflammatory responseGO:005072720.010

hpse disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.028
disease of metabolismDOID:001466700.015
musculoskeletal system diseaseDOID:1700.014
inherited metabolic disorderDOID:65500.014
disease of cellular proliferationDOID:1456600.013
cardiovascular system diseaseDOID:128700.013
organ system cancerDOID:005068600.012
cancerDOID:16200.012
sensory system diseaseDOID:005015500.011
muscle tissue diseaseDOID:6600.011
myopathyDOID:42300.011
muscular diseaseDOID:008000000.011