Danio rerio

15 known processes

fen1

flap structure-specific endonuclease 1

(Aliases: FEN-1,cb879)

fen1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repairGO:000630230.810
Yeast
double strand break repair via homologous recombinationGO:000072410.762
biosynthetic processGO:00090582940.680
Human Yeast Mouse
cellular nitrogen compound metabolic processGO:00346412900.641
Human Yeast Mouse Worm
cellular aromatic compound metabolic processGO:00067252950.611
Human Yeast Mouse Worm
embryo development ending in birth or egg hatchingGO:00097922710.593
Worm
cellular biosynthetic processGO:00442492860.569
Human Yeast Mouse
organic cyclic compound biosynthetic processGO:19013622230.532
Yeast
organic substance biosynthetic processGO:19015762890.456
Human Yeast Mouse
chromosome organizationGO:0051276310.407
Yeast
larval developmentGO:000216420.376
dna metabolic processGO:0006259270.373
Human Yeast Mouse Worm
nucleic acid metabolic processGO:00903042440.326
Human Yeast Mouse Worm
regulation of metabolic processGO:00192223590.285
nucleobase containing compound metabolic processGO:00061392740.274
Human Yeast Mouse Worm
aromatic compound biosynthetic processGO:00194382170.270
Yeast
response to stressGO:00069502630.270
Yeast Mouse
regulation of primary metabolic processGO:00800903110.262
peptidyl lysine acetylationGO:001839420.248
nitrogen compound metabolic processGO:00068073190.238
Human Yeast Mouse Worm
recombinational repairGO:000072510.238
single organism organelle organizationGO:19025891990.237
Yeast
gene expressionGO:00104672520.226
locomotionGO:00400113130.218
Worm
chromatin modificationGO:0016568210.213
cellular response to stressGO:0033554620.211
Yeast Mouse
heterocycle metabolic processGO:00464832900.206
Human Yeast Mouse Worm
protein acetylationGO:000647320.198
heterocycle biosynthetic processGO:00181302150.186
Yeast
cellular macromolecule metabolic processGO:00442603910.176
Human Yeast Mouse Worm
regulation of transcription elongation from rna polymerase ii promoterGO:003424330.172
nucleoside phosphate biosynthetic processGO:1901293210.170
internal protein amino acid acetylationGO:000647520.170
programmed cell deathGO:00125011190.153
Worm
nucleobase containing compound biosynthetic processGO:00346542050.151
Yeast
regulation of nucleobase containing compound metabolic processGO:00192192500.149
regulation of transcription dna templatedGO:00063552130.149
organic cyclic compound metabolic processGO:19013603010.142
Human Yeast Mouse Worm
regulation of nitrogen compound metabolic processGO:00511712510.139
cellular nitrogen compound biosynthetic processGO:00442712180.137
Yeast
macromolecule biosynthetic processGO:00090592270.136
Human Yeast Mouse
regulation of nucleic acid templated transcriptionGO:19035062130.135
regulation of macromolecule metabolic processGO:00602553170.134
cellular response to dna damage stimulusGO:0006974240.128
Yeast Mouse
regulation of cellular metabolic processGO:00313233200.125
rna biosynthetic processGO:00327741810.124
eye developmentGO:00016542770.121
deoxyribonucleotide biosynthetic processGO:000926310.119
sensory organ developmentGO:00074233930.118
regulation of gene expressionGO:00104682650.110
negative regulation of biological processGO:00485193040.110
regulation of biosynthetic processGO:00098892500.108
organelle organizationGO:00069962270.106
Yeast
negative regulation of gene expressionGO:0010629650.103
developmental process involved in reproductionGO:0003006270.101
Yeast Worm
immune system processGO:00023762410.101
rna transportGO:005065820.094
mitotic dna damage checkpointGO:004477340.084
nucleotide biosynthetic processGO:0009165210.082
centrosome organizationGO:005129710.081
immune system developmentGO:00025201910.081
regulation of rna metabolic processGO:00512522240.081
single fertilizationGO:000733830.079
chromatin organizationGO:0006325220.079
establishment of localizationGO:00512342440.078
Worm
regulation of rna biosynthetic processGO:20011412130.078
response to abiotic stimulusGO:00096281220.077
negative regulation of metabolic processGO:0009892860.077
dna biosynthetic processGO:007189730.076
Yeast
internal peptidyl lysine acetylationGO:001839320.075
single organism biosynthetic processGO:0044711710.074
regulation of programmed cell deathGO:00430671010.074
single organism metabolic processGO:00447102170.073
Yeast Mouse
regulation of macromolecule biosynthetic processGO:00105562250.072
regulation of mitotic cell cycle phase transitionGO:190199080.072
mitotic recombinationGO:000631220.071
Yeast
negative regulation of nucleobase containing compound metabolic processGO:0045934590.071
cell cycle g1 s phase transitionGO:004484310.070
negative regulation of rna metabolic processGO:0051253480.070
regulation of proteolysisGO:0030162240.069
single organism localizationGO:19025782250.067
rna metabolic processGO:00160702190.066
Human Yeast
meiotic cell cycle processGO:190304630.064
signal transductionGO:00071654550.063
dna recombinationGO:000631050.063
Yeast
camera type eye developmentGO:00430102220.063
modification dependent protein catabolic processGO:001994130.063
centrosome cycleGO:000709810.062
hemopoiesisGO:00300971830.061
agingGO:000756820.061
Yeast
non recombinational repairGO:000072620.060
Yeast
regulation of transcription from rna polymerase ii promoterGO:00063571140.060
protein metabolic processGO:00195381830.059
regulation of dna templated transcription elongationGO:003278430.059
protein acylationGO:004354330.059
cellular component assemblyGO:00226071700.057
double strand break repair via nonhomologous end joiningGO:000630310.057
Yeast
negative regulation of macromolecule metabolic processGO:0010605760.056
dna repairGO:000628160.056
Yeast Mouse
regulation of apoptotic processGO:0042981980.054
macromolecular complex subunit organizationGO:0043933740.054
cell migrationGO:00164772370.054
dna catabolic processGO:000630810.053
Human Yeast Mouse Worm
g1 s transition of mitotic cell cycleGO:000008210.053
mitotic dna integrity checkpointGO:004477440.053
negative regulation of cellular processGO:00485232830.052
regulation of cellular biosynthetic processGO:00313262450.052
positive regulation of cellular processGO:00485222010.052
gene silencingGO:001645840.051
cellular protein modification processGO:00064641000.051
regulation of cellular macromolecule biosynthetic processGO:20001122220.049
cellular macromolecule biosynthetic processGO:00346452240.049
Human Yeast Mouse
transportGO:00068102200.048
Worm
retina development in camera type eyeGO:00600411460.047
regulation of multicellular organismal processGO:00512392770.047
regulation of response to stimulusGO:00485832690.046
muscle structure developmentGO:00610611960.046
regulation of cell deathGO:00109411030.046
mitotic cell cycle checkpointGO:000709350.046
apoptotic processGO:00069151160.045
Worm
reproductive processGO:0022414400.045
Yeast Worm
cellular component biogenesisGO:00440851780.044
hematopoietic or lymphoid organ developmentGO:00485341910.044
dna templated transcription elongationGO:000635430.043
multi organism processGO:00517041340.042
cell deathGO:00082191210.042
Worm
negative regulation of chromosome organizationGO:200125110.041
negative regulation of macromolecule biosynthetic processGO:0010558480.041
negative regulation of cellular metabolic processGO:0031324770.040
positive regulation of chromatin modificationGO:190331010.039
microtubule based processGO:0007017600.038
cell cycle checkpointGO:000007570.037
regulation of bindingGO:005109830.037
fertilizationGO:000956630.036
cell motilityGO:00488702440.036
catabolic processGO:0009056320.036
Human Yeast Mouse Worm
cellular ketone metabolic processGO:0042180110.036
intra s dna damage checkpointGO:003157310.035
transcription dna templatedGO:00063511810.035
regulation of catalytic activityGO:0050790550.035
multicellular organism growthGO:003526440.034
digestive system developmentGO:00551232890.034
nucleic acid templated transcriptionGO:00976591810.034
organonitrogen compound metabolic processGO:1901564740.034
regulation of dna recombinationGO:000001820.033
positive regulation of cellular catabolic processGO:003133130.033
cell proliferationGO:0008283800.033
protein modification processGO:00362111000.033
cellular amine metabolic processGO:004410620.033
pronuclear migrationGO:003504610.033
mitotic metaphase plate congressionGO:000708010.033
cellular component movementGO:00069283350.032
amine metabolic processGO:000930820.032
regulation of developmental processGO:00507932470.032
response to light stimulusGO:0009416460.032
negative regulation of nucleic acid templated transcriptionGO:1903507450.031
telomere organizationGO:003220010.031
meiosis iGO:000712710.031
negative regulation of nitrogen compound metabolic processGO:0051172590.031
organelle localizationGO:0051640490.031
regulation of cellular amine metabolic processGO:003323800.031
response to drugGO:004249330.031
meiotic nuclear divisionGO:000712640.031
proteolysis involved in cellular protein catabolic processGO:005160330.030
response to chemicalGO:00422213200.030
regulation of deoxyribonuclease activityGO:003207010.030
regulation of molecular functionGO:0065009700.029
macromolecular complex assemblyGO:0065003350.029
protein heterooligomerizationGO:005129110.029
lipid catabolic processGO:001604240.029
small molecule metabolic processGO:0044281770.029
deoxyribonucleotide metabolic processGO:000926210.028
pyrimidine containing compound biosynthetic processGO:007252820.028
protein complex biogenesisGO:0070271300.028
regulation of cellular component organizationGO:0051128860.028
covalent chromatin modificationGO:0016569200.028
cellular response to external stimulusGO:007149620.028
peptidyl serine phosphorylationGO:001810510.028
regulation of hydrolase activityGO:0051336280.028
regulation of establishment of protein localizationGO:007020140.028
leukocyte proliferationGO:007066110.028
neuron projection developmentGO:00311751800.028
regulation of lipid catabolic processGO:005099420.027
positive regulation of transcription elongation from rna polymerase ii promoterGO:003296810.027
rna localizationGO:000640340.027
proteolysisGO:0006508380.027
single organism reproductive processGO:0044702400.027
Yeast Worm
nuclear transportGO:005116940.027
cellular response to chemical stimulusGO:00708871570.026
proteasomal protein catabolic processGO:001049820.026
response to inorganic substanceGO:0010035380.026
response to external stimulusGO:00096052640.026
deathGO:00162651210.025
Worm
regulation of mitotic cell cycleGO:0007346250.025
intracellular signal transductionGO:0035556850.025
mitotic cell cycle processGO:1903047480.025
phosphorus metabolic processGO:00067931090.025
Yeast
regulation of protein metabolic processGO:0051246560.025
regulation of cellular ketone metabolic processGO:001056570.025
positive regulation of catabolic processGO:000989640.025
synaptic growth at neuromuscular junctionGO:005112420.024
negative regulation of cell cycle processGO:001094890.024
response to uvGO:000941130.024
microtubule polymerizationGO:004678520.024
reproductionGO:0000003400.023
Yeast Worm
negative regulation of programmed cell deathGO:0043069580.023
digestive tract developmentGO:00485652650.023
positive regulation of cellular metabolic processGO:0031325940.022
rna 3 end processingGO:003112320.022
heterocycle catabolic processGO:0046700150.022
Human Yeast Mouse Worm
protein complex assemblyGO:0006461300.021
negative regulation of biosynthetic processGO:0009890550.021
positive regulation of nitrogen compound metabolic processGO:0051173690.021
negative regulation of cellular component organizationGO:0051129160.021
organic substance transportGO:0071702580.021
establishment of rna localizationGO:005123630.020
nucleobase containing compound transportGO:001593120.020
meiotic chromosome segregationGO:004513230.020
cell morphogenesisGO:00009022890.020
negative regulation of apoptotic processGO:0043066550.020
regulation of cellular amino acid metabolic processGO:000652100.020
cell cycleGO:0007049930.019
growthGO:00400071740.019
maintenance of locationGO:005123540.019
peptidyl amino acid modificationGO:0018193160.019
cytokinesisGO:000091030.019
nuclear divisionGO:0000280230.019
histone modificationGO:0016570200.018
regulation of biological qualityGO:00650082630.018
protein complex disassemblyGO:004324110.018
cellular protein metabolic processGO:00442671290.018
negative regulation of cell deathGO:0060548600.018
spindle assemblyGO:005122520.018
organic substance catabolic processGO:1901575280.018
Human Yeast Mouse Worm
regulation of cell cycleGO:0051726520.017
regulation of protein catabolic processGO:004217610.017
regulation of protein transportGO:005122330.017
protein polyubiquitinationGO:000020940.017
modification dependent macromolecule catabolic processGO:004363230.017
positive regulation of cell cycleGO:004578730.017
positive regulation of cellular amine metabolic processGO:003324000.017
pyrimidine containing compound metabolic processGO:007252730.017
nucleic acid transportGO:005065720.017
nucleocytoplasmic transportGO:000691340.017
response to external biotic stimulusGO:0043207970.017
organophosphate biosynthetic processGO:0090407230.016
cellular component morphogenesisGO:00329893360.016
reciprocal meiotic recombinationGO:000713110.016
brain developmentGO:00074202930.016
macromolecule modificationGO:00434121110.016
maintenance of dna repeat elementsGO:004357020.016
Yeast
negative regulation of mitotic cell cycleGO:0045930110.016
cellular lipid catabolic processGO:004424230.016
purine nucleoside monophosphate catabolic processGO:000912840.016
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.016
regulation of cell differentiationGO:00455951420.016
regulation of response to stressGO:0080134360.016
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
macromolecule localizationGO:0033036540.016
carbohydrate derivative metabolic processGO:1901135610.015
regulation of peptidase activityGO:0052547230.015
adult behaviorGO:003053420.015
cellular protein catabolic processGO:004425740.015
mitotic cell cycleGO:0000278640.015
establishment of localization in cellGO:0051649770.015
establishment of protein localization to organelleGO:007259440.015
regulation of cellular protein metabolic processGO:0032268520.015
regulation of dna replicationGO:000627530.015
regulation of gene silencingGO:006096810.014
positive regulation of histone modificationGO:003105810.014
phosphate containing compound metabolic processGO:00067961080.014
Yeast
response to alkaloidGO:004327920.014
embryonic digestive tract morphogenesisGO:004855730.014
mrna transportGO:005102820.014
microtubule cytoskeleton organizationGO:0000226330.014
organic acid metabolic processGO:0006082310.014
positive regulation of transportGO:005105020.013
regulation of protein ubiquitinationGO:003139630.013
mrna metabolic processGO:0016071200.013
establishment of organelle localizationGO:0051656450.013
dna integrity checkpointGO:003157060.013
carboxylic acid metabolic processGO:0019752220.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280100.013
nucleotide metabolic processGO:0009117280.013
positive regulation of dna metabolic processGO:005105410.013
negative regulation of nuclear divisionGO:005178430.013
regulation of meiotic cell cycleGO:005144510.013
heart developmentGO:00075073130.013
regulation of gene expression epigeneticGO:0040029110.013
cytoskeleton organizationGO:0007010960.013
macromolecular complex disassemblyGO:003298410.013
negative regulation of cellular biosynthetic processGO:0031327550.013
establishment of mitotic spindle orientationGO:0000132100.013
carbohydrate derivative biosynthetic processGO:1901137430.013
negative regulation of cell cycle phase transitionGO:190198850.012
response to metal ionGO:0010038340.012
negative regulation of mitosisGO:004583930.012
cellular nitrogen compound catabolic processGO:0044270150.012
Human Yeast Mouse Worm
histone phosphorylationGO:001657220.012
regulation of signal transductionGO:00099662250.012
protein targeting to nucleusGO:004474430.012
microtubule organizing center organizationGO:003102310.012
negative regulation of transcription dna templatedGO:0045892450.012
reciprocal dna recombinationGO:003582510.012
developmental growthGO:00485891660.012
nucleoside phosphate metabolic processGO:0006753280.012
ubiquitin dependent protein catabolic processGO:000651130.012
response to radiationGO:0009314510.012
striated muscle cell differentiationGO:00511461290.011
positive regulation of nuclease activityGO:003207510.011
localization of cellGO:00516742440.011
regulation of cytoplasmic transportGO:190364940.011
mrna processingGO:0006397140.011
regulation of nucleocytoplasmic transportGO:004682220.011
negative regulation of cellular catabolic processGO:003133030.011
cell surface receptor signaling pathwayGO:00071663250.011
purine ribonucleoside monophosphate catabolic processGO:000916940.011
intestinal cholesterol absorptionGO:003029920.011
negative regulation of mitotic cell cycle phase transitionGO:190199150.011
atp catabolic processGO:000620040.011
negative regulation of response to stimulusGO:00485851040.011
response to organic substanceGO:00100331530.011
macromolecule catabolic processGO:0009057150.011
Human Yeast Mouse Worm
embryonic organ developmentGO:00485683810.011
positive regulation of lipid metabolic processGO:004583410.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.011
cellular amino acid metabolic processGO:000652070.011
regulation of signalingGO:00230512350.011
positive regulation of biological processGO:00485182530.011
apoptotic signaling pathwayGO:0097190230.011
negative regulation of intracellular transportGO:003238730.010
cellular localizationGO:0051641970.010
cell cycle processGO:0022402530.010
oxoacid metabolic processGO:0043436310.010
cellular catabolic processGO:0044248270.010
Human Yeast Mouse Worm
sex differentiationGO:000754850.010
Worm
cellular macromolecular complex assemblyGO:0034622240.010
negative regulation of cell cycleGO:0045786140.010
cellular response to organic substanceGO:00713101050.010
epithelial cell differentiationGO:00308551160.010
immunoglobulin mediated immune responseGO:001606430.010

fen1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.016
disease of anatomical entityDOID:700.016