Danio rerio

0 known processes

insig1

insulin induced gene 1

(Aliases: wu:fi35b10,zgc:55439,fb55a03,wu:fb55a03,fi35b10)

insig1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
organic substance biosynthetic processGO:19015762890.109
Human Mouse
lipid storageGO:001991510.106
larval developmentGO:000216420.088
cellular carbohydrate metabolic processGO:004426240.065
locomotionGO:00400113130.059
central nervous system developmentGO:00074173870.058
maintenance of locationGO:005123540.054
regulation of signal transductionGO:00099662250.050
establishment of protein localization to organelleGO:007259440.048
establishment of localizationGO:00512342440.046
Human
long chain fatty acid metabolic processGO:000167610.045
regulation of macromolecule metabolic processGO:00602553170.044
Human
negative regulation of biological processGO:00485193040.043
Human Mouse
agingGO:000756820.041
response to stressGO:00069502630.041
Human Mouse
regulation of primary metabolic processGO:00800903110.040
Human Mouse
amine metabolic processGO:000930820.040
nuclear transportGO:005116940.040
heterocycle metabolic processGO:00464832900.040
Human
macromolecule biosynthetic processGO:00090592270.039
Human
cellular macromolecule biosynthetic processGO:00346452240.038
Human
positive regulation of transportGO:005105020.038
single organism nuclear importGO:190259330.035
protein localization to nucleusGO:003450430.035
protein import into nucleusGO:000660630.035
regulation of synapse organizationGO:005080730.034
meiotic nuclear divisionGO:000712640.033
phagocytosisGO:000690930.033
cellular response to external stimulusGO:007149620.033
regulation of synaptic growth at neuromuscular junctionGO:000858210.032
nitrogen compound metabolic processGO:00068073190.032
Human
small molecule metabolic processGO:0044281770.031
Mouse
positive regulation of cell cycleGO:004578730.030
lateral inhibitionGO:004633110.030
embryonic organ developmentGO:00485683810.030
Mouse
single organism metabolic processGO:00447102170.029
Mouse
synaptic growth at neuromuscular junctionGO:005112420.029
response to nutrientGO:000758430.028
sensory organ developmentGO:00074233930.028
Mouse
multicellular organism growthGO:003526440.028
nucleocytoplasmic transportGO:000691340.028
cellular biosynthetic processGO:00442492860.028
Human Mouse
heterocycle biosynthetic processGO:00181302150.028
Human
negative regulation of cellular processGO:00485232830.028
Human Mouse
gene expressionGO:00104672520.027
Human
carbohydrate biosynthetic processGO:001605110.027
positive regulation of cellular component biogenesisGO:004408930.027
nucleobase containing compound metabolic processGO:00061392740.027
Human
regulation of ion transmembrane transporter activityGO:003241220.027
regulation of multicellular organism growthGO:004001440.027
cellular macromolecule metabolic processGO:00442603910.026
Human
nuclear importGO:005117030.026
cellular amine metabolic processGO:004410620.026
cellular response to radiationGO:007147840.026
organic cyclic compound metabolic processGO:19013603010.026
Human Mouse
signal transductionGO:00071654550.025
Human
rna metabolic processGO:00160702190.025
Human
regulation of gene expressionGO:00104682650.025
Human
aromatic compound biosynthetic processGO:00194382170.025
Human
rna biosynthetic processGO:00327741810.025
Human
i kappab kinase nf kappab signalingGO:000724940.025
cell surface receptor signaling pathwayGO:00071663250.025
response to corticosteroidGO:003196010.025
protein targeting to nucleusGO:004474430.025
regulation of cellular amino acid metabolic processGO:000652100.025
golgi vesicle transportGO:004819330.024
Human
morphogenesis of an epitheliumGO:00020093330.024
stem cell proliferationGO:007208940.024
regulation of sodium ion transportGO:000202820.024
positive regulation of catabolic processGO:000989640.024
regulation of signalingGO:00230512350.024
nucleobase containing compound biosynthetic processGO:00346542050.024
Human
negative regulation of protein kinase activityGO:000646940.024
adult behaviorGO:003053420.023
single organism localizationGO:19025782250.023
Human
negative regulation of protein phosphorylationGO:000193340.023
regulation of developmental processGO:00507932470.023
Mouse
cellular response to nutrient levelsGO:003166920.023
transportGO:00068102200.023
Human
regulation of blood vessel sizeGO:005088020.023
cell cycle g1 s phase transitionGO:004484310.023
response to amino acidGO:004320020.023
regulation of metal ion transportGO:001095940.023
response to vitaminGO:003327330.023
organic acid metabolic processGO:0006082310.022
Mouse
cellular response to stressGO:0033554620.022
Human
organic cyclic compound biosynthetic processGO:19013622230.022
Human Mouse
regulation of cell communicationGO:00106462320.022
regulation of cellular biosynthetic processGO:00313262450.022
Human Mouse
gland developmentGO:00487321430.021
negative regulation of kinase activityGO:003367340.021
extrinsic apoptotic signaling pathwayGO:009719130.021
regulation of transmembrane transporter activityGO:002289820.021
regulation of intracellular protein transportGO:003315730.021
phagocytosis engulfmentGO:000691110.021
endosomal transportGO:001619720.021
regulation of protein import into nucleusGO:004230620.021
regulation of cellular amine metabolic processGO:003323800.021
positive regulation of cellular amino acid metabolic processGO:004576400.020
pyruvate metabolic processGO:000609010.020
regulation of dna replicationGO:000627530.020
intracellular signal transductionGO:0035556850.020
cellular response to extracellular stimulusGO:003166820.020
response to alkaloidGO:004327920.020
carboxylic acid metabolic processGO:0019752220.020
Mouse
alcohol biosynthetic processGO:004616520.020
Mouse
response to chemicalGO:00422213200.020
positive regulation of biological processGO:00485182530.020
Human
regulation of epithelial cell proliferationGO:005067830.020
biosynthetic processGO:00090582940.019
Human Mouse
immune system processGO:00023762410.019
brain developmentGO:00074202930.019
cellular nitrogen compound biosynthetic processGO:00442712180.019
Human
regulation of macromolecule biosynthetic processGO:00105562250.019
Human
generation of neuronsGO:00486993850.019
head developmentGO:00603223030.019
regulation of tube sizeGO:003515020.019
female sex differentiationGO:004666040.019
hormone biosynthetic processGO:004244630.019
superoxide metabolic processGO:000680120.018
regulation of synapse assemblyGO:005196330.018
negative regulation of mapk cascadeGO:004340940.018
regulation of establishment of protein localizationGO:007020140.018
protein importGO:001703830.018
regionalizationGO:00030022740.018
cellular component movementGO:00069283350.018
organonitrogen compound metabolic processGO:1901564740.018
positive regulation of cellular amine metabolic processGO:003324000.018
negative regulation of catabolic processGO:000989530.018
alpha amino acid metabolic processGO:190160530.018
eye developmentGO:00016542770.018
chemosensory behaviorGO:000763510.018
regulation of protein targetingGO:190353320.018
positive regulation of cellular catabolic processGO:003133130.018
meiotic cell cycle processGO:190304630.018
response to organic substanceGO:00100331530.018
single organism biosynthetic processGO:0044711710.018
Mouse
regulation of cytoplasmic transportGO:190364940.018
Human
cellular nitrogen compound metabolic processGO:00346412900.018
Human
regulation of nucleoside metabolic processGO:000911820.018
response to drugGO:004249330.018
apoptotic processGO:00069151160.018
zinc ion transportGO:000682920.018
guanosine containing compound metabolic processGO:190106840.018
membrane invaginationGO:001032410.017
regulation of reactive oxygen species metabolic processGO:200037720.017
negative regulation of signalingGO:0023057960.017
regulation of metabolic processGO:00192223590.017
Human Mouse
protein metabolic processGO:00195381830.017
mononuclear cell proliferationGO:003294310.017
regulation of reproductive processGO:200024140.017
cellular response to chemical stimulusGO:00708871570.017
lymphocyte proliferationGO:004665110.017
positive regulation of protein complex assemblyGO:003133420.017
regulation of cellular carbohydrate metabolic processGO:001067540.017
regulation of stem cell differentiationGO:200073640.017
phosphorus metabolic processGO:00067931090.017
regulation of cell projection assemblyGO:006049140.017
lipid metabolic processGO:0006629520.017
Mouse
protein dephosphorylationGO:000647030.017
peptidyl serine phosphorylationGO:001810510.017
tissue remodelingGO:004877140.017
cellular ketone metabolic processGO:0042180110.017
Mouse
regulation of protein complex assemblyGO:004325430.017
Human
regulation of cellular ketone metabolic processGO:001056570.017
Mouse
regulation of peptidyl tyrosine phosphorylationGO:005073010.017
system processGO:00030081850.016
positive regulation of cellular processGO:00485222010.016
Human
positive regulation of nucleoside metabolic processGO:004597910.016
ubiquitin dependent protein catabolic processGO:000651130.016
regulation of i kappab kinase nf kappab signalingGO:004312240.016
neuron developmentGO:00486662620.016
hormone secretionGO:004687920.016
oxoacid metabolic processGO:0043436310.016
Mouse
embryonic organ morphogenesisGO:00485622740.016
Mouse
negative regulation of metabolic processGO:0009892860.016
Mouse
camera type eye developmentGO:00430102220.016
regulation of nucleotide catabolic processGO:003081120.015
glucose homeostasisGO:004259310.015
leukocyte proliferationGO:007066110.015
tube morphogenesisGO:00352393490.015
regulation of response to stimulusGO:00485832690.015
cell cycle arrestGO:000705010.015
autophagyGO:000691440.015
growthGO:00400071740.015
regulation of transcription dna templatedGO:00063552130.015
Human
protein polymerizationGO:005125840.015
regulation of cytokine productionGO:000181730.015
ovulation cycleGO:004269820.015
regulation of cell activationGO:005086510.015
positive regulation of protein polymerizationGO:003227320.015
proteasomal protein catabolic processGO:001049820.015
response to glucocorticoidGO:005138410.015
g1 s transition of mitotic cell cycleGO:000008210.015
regulation of erk1 and erk2 cascadeGO:007037240.015
protein stabilizationGO:005082120.015
regulation of transporter activityGO:003240920.014
compound eye developmentGO:004874920.014
glial cell differentiationGO:0010001420.014
multi organism processGO:00517041340.014
development of primary female sexual characteristicsGO:004654540.014
female gonad developmentGO:000858540.014
cellular response to starvationGO:000926710.014
response to hexoseGO:000974630.014
stem cell maintenanceGO:001982740.014
regulation of biosynthetic processGO:00098892500.014
Human Mouse
locomotor rhythmGO:004547530.014
embryo development ending in birth or egg hatchingGO:00097922710.014
cell migrationGO:00164772370.014
circulatory system processGO:0003013870.014
cartilage developmentGO:0051216960.014
cellular component morphogenesisGO:00329893360.014
peptidyl serine modificationGO:001820920.014
regulation of nucleic acid templated transcriptionGO:19035062130.014
Human
hormone transportGO:000991420.014
cell morphogenesisGO:00009022890.014
regulation of protein localization to nucleusGO:190018020.014
modification dependent macromolecule catabolic processGO:004363230.014
gtp metabolic processGO:004603940.014
modification dependent protein catabolic processGO:001994130.014
cellular lipid metabolic processGO:0044255360.014
Mouse
b cell activationGO:004211320.014
positive regulation of secretionGO:005104710.014
positive regulation of cellular carbohydrate metabolic processGO:001067610.014
response to glucoseGO:000974930.014
transmembrane transportGO:00550851200.014
cell agingGO:000756920.014
response to carbohydrateGO:000974330.014
regulation of cell shapeGO:000836010.013
vasculature developmentGO:00019442780.013
regulation of epidermis developmentGO:004568220.013
proteolysis involved in cellular protein catabolic processGO:005160330.013
cellular amino acid metabolic processGO:000652070.013
regulation of meiotic cell cycleGO:005144510.013
regulation of rna metabolic processGO:00512522240.013
Human
carbohydrate homeostasisGO:003350010.013
protein localization to plasma membraneGO:007265910.013
dorsal ventral pattern formationGO:00099531250.013
negative regulation of cell communicationGO:0010648960.013
stem cell divisionGO:001714510.013
regulation of bindingGO:005109830.013
zymogen activationGO:003163830.013
blood vessel developmentGO:00015682460.013
multicellular organismal response to stressGO:003355520.013
regulation of blood pressureGO:000821710.013
hematopoietic or lymphoid organ developmentGO:00485341910.013
nucleoside monophosphate catabolic processGO:000912540.013
oocyte maturationGO:000155640.013
response to uvGO:000941130.013
cellular response to retinoic acidGO:007130010.013
guanosine containing compound catabolic processGO:190106920.013
digestive tract morphogenesisGO:00485462310.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073110.013
amino acid transportGO:000686520.013
cognitionGO:005089010.013
protein heterooligomerizationGO:005129110.013
cellular response to organic substanceGO:00713101050.013
protein acetylationGO:000647320.013
cytokinesisGO:000091030.013
positive regulation of striated muscle cell differentiationGO:005115510.013
centrosome organizationGO:005129710.013
immune system developmentGO:00025201910.013
negative regulation of protein complex assemblyGO:003133310.013
Human
regulation of filopodium assemblyGO:005148920.013
regulation of response to nutrient levelsGO:003210710.013
lipid homeostasisGO:005508830.013
regulation of cellular metabolic processGO:00313233200.013
Human Mouse
fertilizationGO:000956630.012
cell motilityGO:00488702440.012
positive regulation of cell adhesionGO:004578510.012
negative regulation of macromolecule metabolic processGO:0010605760.012
cellular component assemblyGO:00226071700.012
Human
regulation of neural precursor cell proliferationGO:200017730.012
regulation of jun kinase activityGO:004350630.012
catechol containing compound metabolic processGO:000971220.012
macromolecular complex disassemblyGO:003298410.012
reactive oxygen species metabolic processGO:007259360.012
oxidation reduction processGO:0055114410.012
energy reserve metabolic processGO:000611220.012
programmed cell deathGO:00125011190.012
response to monosaccharideGO:003428430.012
regulation of nucleocytoplasmic transportGO:004682220.012
p38mapk cascadeGO:003806610.012
positive regulation of nucleotide catabolic processGO:003081310.012
response to hydrogen peroxideGO:004254230.012
sensory organ morphogenesisGO:00905962000.012
Mouse
response to oxygen containing compoundGO:1901700550.012
myeloid cell homeostasisGO:0002262560.012
zinc ion transmembrane transportGO:007157710.012
positive regulation of cytoskeleton organizationGO:005149530.012
specification of symmetryGO:00097992040.012
protein acylationGO:004354330.012
determination of bilateral symmetryGO:00098552040.012
synaptic vesicle endocytosisGO:004848810.012
regulation of molecular functionGO:0065009700.012
synaptic vesicle localizationGO:009747910.012
hemopoiesisGO:00300971830.012
germ line stem cell maintenanceGO:003071820.012
negative regulation of cytoplasmic transportGO:190365020.012
Human
cell substrate adhesionGO:003158940.012
symbiosis encompassing mutualism through parasitismGO:004440340.011
regulation of protein transportGO:005122330.011
deathGO:00162651210.011
mitochondrion organizationGO:000700540.011
transcription dna templatedGO:00063511810.011
Human
regulation of systemic arterial blood pressureGO:000307310.011
ear developmentGO:00435831270.011
Mouse
positive regulation of carbohydrate metabolic processGO:004591310.011
nuclear migrationGO:000709730.011
long chain fatty acid transportGO:001590910.011
response to external stimulusGO:00096052640.011
regulation of myotube differentiationGO:001083020.011
negative regulation of intracellular protein transportGO:009031730.011
regulation of circadian rhythmGO:004275240.011
cellular modified amino acid metabolic processGO:000657530.011
regulation of skeletal muscle tissue developmentGO:004864140.011
lipid catabolic processGO:001604240.011
response to endogenous stimulusGO:0009719830.011
regulation of nitrogen compound metabolic processGO:00511712510.011
Human
regulation of protein catabolic processGO:004217610.011
primary neural tube formationGO:001402010.011
regulation of biological qualityGO:00650082630.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.011
erk1 and erk2 cascadeGO:007037140.011
phosphatidylinositol 3 kinase signalingGO:001406520.011
neurotransmitter transportGO:000683620.011
skeletal system developmentGO:00015011810.011
Mouse
gastrulationGO:00073692080.011
heart developmentGO:00075073130.011
digestive system developmentGO:00551232890.011
endocrine processGO:005088620.011
positive regulation of purine nucleotide catabolic processGO:003312310.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.011
regulation of gtpase activityGO:004308720.011
connective tissue developmentGO:0061448990.011
rna localizationGO:000640340.011
negative regulation of nucleocytoplasmic transportGO:004682320.011
entrainment of circadian clockGO:000964920.011
positive regulation of i kappab kinase nf kappab signalingGO:004312330.011
negative regulation of protein serine threonine kinase activityGO:007190120.011
post golgi vesicle mediated transportGO:000689210.011
dopamine metabolic processGO:004241720.011
gliogenesisGO:0042063450.011
cation transmembrane transportGO:0098655650.011
photoreceptor cell fate commitmentGO:004655210.011
notochord developmentGO:0030903540.011
axon ensheathment in central nervous systemGO:003229120.011
cellular component disassemblyGO:002241110.011
positive regulation of secretion by cellGO:190353210.011
transcription from rna polymerase ii promoterGO:0006366800.011
Human
single fertilizationGO:000733830.011
positive regulation of map kinase activityGO:004340630.011
regulation of cellular protein catabolic processGO:190336210.011
calcium ion importGO:007050940.011
localization of cellGO:00516742440.010
somatic muscle developmentGO:000752540.010
synaptic vesicle recyclingGO:003646510.010
cell matrix adhesionGO:000716040.010
tyrosine phosphorylation of stat proteinGO:000726010.010
cellular monovalent inorganic cation homeostasisGO:003000420.010
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.010
negative regulation of small gtpase mediated signal transductionGO:005105810.010
regulation of phGO:000688530.010
proteasome mediated ubiquitin dependent protein catabolic processGO:004316120.010
regulation of hormone secretionGO:004688320.010
regulation of gtp catabolic processGO:003312420.010
regulation of response to extracellular stimulusGO:003210410.010
fatty acid transportGO:001590810.010
smooth muscle contractionGO:000693920.010
protein homooligomerizationGO:005126030.010
peptide transportGO:001583310.010
regulation of p38mapk cascadeGO:190074410.010
positive regulation of nitrogen compound metabolic processGO:0051173690.010
Human
epithelial tube morphogenesisGO:00605621480.010
regulation of purine nucleotide catabolic processGO:003312120.010
cellular response to reactive oxygen speciesGO:003461420.010
secondary metabolic processGO:001974830.010
digestive tract developmentGO:00485652650.010
cell deathGO:00082191210.010
regulation of apoptotic processGO:0042981980.010

insig1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.036
disease of anatomical entityDOID:700.017
inherited metabolic disorderDOID:65500.017
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
nervous system diseaseDOID:86300.014
sensory system diseaseDOID:005015500.010