Danio rerio

13 known processes

raf1a

v-raf-1 murine leukemia viral oncogene homolog 1a

(Aliases: c-raf,raf1,craf)

raf1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
convergent extension involved in gastrulationGO:0060027710.214
muscle cell developmentGO:00550011150.177
regulation of gene expressionGO:00104682650.173
organic cyclic compound biosynthetic processGO:19013622230.172
organic cyclic compound metabolic processGO:19013603010.163
heart developmentGO:00075073130.163
bmp signaling pathwayGO:0030509520.149
heterocycle metabolic processGO:00464832900.137
nitrogen compound metabolic processGO:00068073190.121
cellular nitrogen compound biosynthetic processGO:00442712180.121
nucleobase containing compound metabolic processGO:00061392740.121
pathway restricted smad protein phosphorylationGO:006038910.120
nucleic acid metabolic processGO:00903042440.120
head developmentGO:00603223030.116
regulation of cellular macromolecule biosynthetic processGO:20001122220.114
blood vessel developmentGO:00015682460.109
regulation of nucleobase containing compound metabolic processGO:00192192500.107
regulation of signalingGO:00230512350.107
cell morphogenesisGO:00009022890.105
macromolecule biosynthetic processGO:00090592270.100
nucleobase containing compound biosynthetic processGO:00346542050.099
regulation of cell communicationGO:00106462320.098
axonogenesisGO:00074091520.097
gastrulationGO:00073692080.096
regulation of protein localization to nucleusGO:190018020.092
signal transductionGO:00071654550.091
positive regulation of cell cycleGO:004578730.091
regulation of transcription dna templatedGO:00063552130.089
single organism metabolic processGO:00447102170.085
biosynthetic processGO:00090582940.084
regulation of multicellular organismal processGO:00512392770.083
tube morphogenesisGO:00352393490.083
cell projection organizationGO:00300302840.082
regulation of cellular metabolic processGO:00313233200.081
striated muscle cell developmentGO:00550021080.079
nucleic acid templated transcriptionGO:00976591810.079
cellular component movementGO:00069283350.076
regulation of response to stimulusGO:00485832690.075
rna biosynthetic processGO:00327741810.073
regulation of multicellular organism growthGO:004001440.073
striated muscle cell differentiationGO:00511461290.072
cellular macromolecule metabolic processGO:00442603910.072
transcription dna templatedGO:00063511810.071
cellular aromatic compound metabolic processGO:00067252950.071
regulation of primary metabolic processGO:00800903110.070
cellular response to chemical stimulusGO:00708871570.070
organic substance biosynthetic processGO:19015762890.069
apoptotic processGO:00069151160.068
cell morphogenesis involved in differentiationGO:00009041950.066
cellular response to organic substanceGO:00713101050.066
response to chemicalGO:00422213200.065
aromatic compound biosynthetic processGO:00194382170.064
muscle cell differentiationGO:00426921390.063
regulation of developmental processGO:00507932470.063
regulation of biosynthetic processGO:00098892500.063
organelle organizationGO:00069962270.063
vasculature developmentGO:00019442780.063
gene expressionGO:00104672520.061
phagocytosisGO:000690930.060
embryonic organ developmentGO:00485683810.060
meiotic nuclear divisionGO:000712640.059
determination of heart left right asymmetryGO:00613711170.059
regulation of establishment of protein localizationGO:007020140.059
blood vessel morphogenesisGO:00485142160.057
larval developmentGO:000216420.056
muscle structure developmentGO:00610611960.056
transportGO:00068102200.055
nucleocytoplasmic transportGO:000691340.055
regulation of cellular biosynthetic processGO:00313262450.055
response to organic substanceGO:00100331530.054
cellular component morphogenesisGO:00329893360.054
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.053
digestive tract morphogenesisGO:00485462310.052
locomotionGO:00400113130.050
heterocycle biosynthetic processGO:00181302150.049
regulation of macromolecule biosynthetic processGO:00105562250.047
regulation of protein transportGO:005122330.047
embryonic heart tube morphogenesisGO:00031431080.047
morphogenesis of an epitheliumGO:00020093330.047
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.046
multicellular organism growthGO:003526440.045
skeletal system developmentGO:00015011810.045
cell projection morphogenesisGO:00488582440.045
cellular nitrogen compound metabolic processGO:00346412900.044
regulation of rna metabolic processGO:00512522240.043
central nervous system developmentGO:00074173870.042
negative regulation of protein phosphorylationGO:000193340.042
immune system processGO:00023762410.042
agingGO:000756820.041
establishment of localizationGO:00512342440.041
single organism organelle organizationGO:19025891990.040
negative regulation of biological processGO:00485193040.040
enzyme linked receptor protein signaling pathwayGO:00071671060.039
embryonic organ morphogenesisGO:00485622740.039
stem cell maintenanceGO:001982740.039
response to growth factorGO:0070848390.038
regulation of oocyte developmentGO:006028130.038
digestive tract developmentGO:00485652650.038
amine metabolic processGO:000930820.038
erk1 and erk2 cascadeGO:007037140.037
negative regulation of synapse assemblyGO:005196420.037
cellular macromolecule biosynthetic processGO:00346452240.037
determination of left right symmetryGO:00073681790.037
kidney developmentGO:0001822920.037
positive regulation of transportGO:005105020.036
regulation of meiotic cell cycleGO:005144510.036
rna metabolic processGO:00160702190.036
regulation of apoptotic processGO:0042981980.036
nuclear exportGO:005116810.036
convergent extensionGO:00600261180.036
regulation of autophagyGO:001050630.035
cellular biosynthetic processGO:00442492860.035
ear developmentGO:00435831270.035
regulation of nitrogen compound metabolic processGO:00511712510.035
protein localization to nucleusGO:003450430.035
regulation of circadian rhythmGO:004275240.034
organic acid metabolic processGO:0006082310.034
regulation of cell deathGO:00109411030.034
embryo development ending in birth or egg hatchingGO:00097922710.033
cellular protein modification processGO:00064641000.033
small molecule metabolic processGO:0044281770.033
positive regulation of biological processGO:00485182530.033
protein polymerizationGO:005125840.032
synaptic growth at neuromuscular junctionGO:005112420.032
muscle fiber developmentGO:0048747520.032
regulation of synapse organizationGO:005080730.032
extrinsic apoptotic signaling pathwayGO:009719130.032
establishment of protein localization to plasma membraneGO:009000210.031
regulation of cellular amine metabolic processGO:003323800.030
determination of ventral identityGO:0048264210.030
specification of symmetryGO:00097992040.030
positive regulation of map kinase activityGO:004340630.030
cellular component assemblyGO:00226071700.029
cellular localizationGO:0051641970.029
nuclear transportGO:005116940.029
negative regulation of protein kinase activityGO:000646940.029
cell deathGO:00082191210.029
positive regulation of erk1 and erk2 cascadeGO:007037420.028
deathGO:00162651210.028
regulation of signal transductionGO:00099662250.028
cellular component biogenesisGO:00440851780.028
oocyte maturationGO:000155640.028
sensory organ developmentGO:00074233930.028
oxoacid metabolic processGO:0043436310.028
anatomical structure arrangementGO:004853220.027
regulation of metabolic processGO:00192223590.027
regulation of synapse assemblyGO:005196330.027
hormone secretionGO:004687920.027
regulation of cell differentiationGO:00455951420.027
neuron developmentGO:00486662620.027
negative regulation of nucleobase containing compound metabolic processGO:0045934590.027
regionalizationGO:00030022740.027
protein metabolic processGO:00195381830.027
regulation of bindingGO:005109830.027
multi organism processGO:00517041340.026
single organism localizationGO:19025782250.026
regulation of receptor activityGO:001046920.026
brain developmentGO:00074202930.026
cell matrix adhesionGO:000716040.026
digestive system developmentGO:00551232890.026
regulation of multicellular organismal developmentGO:20000262230.026
response to external stimulusGO:00096052640.026
regulation of nucleic acid templated transcriptionGO:19035062130.026
regulation of cellular ketone metabolic processGO:001056570.025
regulation of cellular amino acid metabolic processGO:000652100.025
cognitionGO:005089010.025
skeletal system morphogenesisGO:00487051020.025
determination of bilateral symmetryGO:00098552040.025
transcription from rna polymerase ii promoterGO:0006366800.025
negative regulation of apoptotic processGO:0043066550.025
regulation of dna replicationGO:000627530.024
negative regulation of cellular processGO:00485232830.024
carboxylic acid metabolic processGO:0019752220.024
alpha amino acid metabolic processGO:190160530.024
endocardial cushion formationGO:000327220.024
pharyngeal muscle developmentGO:004328240.024
regulation of organ growthGO:004662030.024
regulation of extrinsic apoptotic signaling pathwayGO:200123630.024
cellular ketone metabolic processGO:0042180110.024
gtp catabolic processGO:000618420.024
cell migration involved in gastrulationGO:0042074790.023
response to abiotic stimulusGO:00096281220.023
negative regulation of catabolic processGO:000989530.023
cell surface receptor signaling pathwayGO:00071663250.023
regulation of stem cell differentiationGO:200073640.023
regulation of protein complex assemblyGO:004325430.022
guanosine containing compound metabolic processGO:190106840.022
positive regulation of dna metabolic processGO:005105410.021
homeostatic processGO:00425921420.021
regulation of intracellular protein transportGO:003315730.021
negative regulation of nitrogen compound metabolic processGO:0051172590.021
regulation of programmed cell deathGO:00430671010.021
positive regulation of cellular processGO:00485222010.021
renal system developmentGO:0072001940.021
anterior posterior pattern specificationGO:00099521520.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
odontogenesis of dentin containing toothGO:004247510.021
regulation of erk1 and erk2 cascadeGO:007037240.020
internal protein amino acid acetylationGO:000647520.020
somatic muscle developmentGO:000752540.020
single organism transportGO:00447652060.020
generation of neuronsGO:00486993850.020
gland developmentGO:00487321430.020
epithelial tube morphogenesisGO:00605621480.020
cell part morphogenesisGO:00329902460.020
neuron projection morphogenesisGO:00488121610.020
developmental growthGO:00485891660.020
mesoderm developmentGO:0007498880.020
cellular amino acid metabolic processGO:000652070.020
inner ear developmentGO:00488391260.020
mesenchyme developmentGO:00604851270.020
macromolecular complex subunit organizationGO:0043933740.020
regulation of nervous system developmentGO:0051960900.019
regulation of rna biosynthetic processGO:20011412130.019
response to endogenous stimulusGO:0009719830.019
negative regulation of cell communicationGO:0010648960.019
negative regulation of cellular metabolic processGO:0031324770.019
dorsal ventral pattern formationGO:00099531250.019
hormone transportGO:000991420.019
chordate embryonic developmentGO:00430092710.019
regulation of cytokine productionGO:000181730.019
gtp metabolic processGO:004603940.019
cellular response to oxygen levelsGO:007145310.019
peptidyl serine phosphorylationGO:001810510.019
intracellular signal transductionGO:0035556850.019
cellular response to endogenous stimulusGO:0071495680.019
negative regulation of rna metabolic processGO:0051253480.019
regulation of nucleoside metabolic processGO:000911820.018
renal tubule morphogenesisGO:006133310.018
regulation of protein targetingGO:190353320.018
negative regulation of cell deathGO:0060548600.018
negative regulation of dna metabolic processGO:005105340.018
regulation of bmp signaling pathwayGO:0030510390.018
maintenance of locationGO:005123540.018
cellular protein catabolic processGO:004425740.018
protein acylationGO:004354330.018
autophagyGO:000691440.018
chromatin organizationGO:0006325220.018
regulation of bone mineralizationGO:003050020.018
response to organic cyclic compoundGO:0014070510.018
lipid storageGO:001991510.018
positive regulation of cytoskeleton organizationGO:005149530.017
cellular response to hormone stimulusGO:0032870390.017
protein importGO:001703830.017
regulation of protein catabolic processGO:004217610.017
activation of mapk activityGO:000018730.017
negative regulation of response to stimulusGO:00485851040.017
carbohydrate biosynthetic processGO:001605110.017
glucose homeostasisGO:004259310.017
protein stabilizationGO:005082120.017
heart joggingGO:0003146400.017
regulation of blood pressureGO:000821710.016
negative regulation of programmed cell deathGO:0043069580.016
protein localizationGO:0008104400.016
regulation of cell substrate adhesionGO:001081010.016
muscle cell migrationGO:001481240.016
regulation of phosphorus metabolic processGO:0051174430.016
cell cycle g1 s phase transitionGO:004484310.016
axon developmentGO:00615641660.016
peptidyl lysine acetylationGO:001839420.016
glial cell migrationGO:000834730.016
negative regulation of signal transductionGO:0009968940.016
programmed cell deathGO:00125011190.016
negative regulation of signalingGO:0023057960.016
regulation of nucleocytoplasmic transportGO:004682220.016
regulation of tube sizeGO:003515020.016
regulation of synaptic plasticityGO:004816710.016
histone methylationGO:0016571130.016
negative regulation of cellular biosynthetic processGO:0031327550.016
taxisGO:00423301090.016
negative regulation of macromolecule metabolic processGO:0010605760.016
response to decreased oxygen levelsGO:0036293250.016
dna metabolic processGO:0006259270.015
cellular carbohydrate metabolic processGO:004426240.015
cellular response to hypoxiaGO:007145610.015
gastrulation with mouth forming secondGO:0001702440.015
chromosome organizationGO:0051276310.015
response to dexamethasoneGO:007154810.015
regulation of biomineral tissue developmentGO:007016720.015
positive regulation of metabolic processGO:00098931080.015
regulation of protein import into nucleusGO:004230620.015
positive regulation of cell adhesionGO:004578510.015
response to corticosteroidGO:003196010.015
cell substrate adhesionGO:003158940.015
cellular response to decreased oxygen levelsGO:003629410.015
regulation of reactive oxygen species metabolic processGO:200037720.015
establishment of protein localization to organelleGO:007259440.015
meiotic chromosome segregationGO:004513230.015
positive regulation of muscle cell differentiationGO:005114910.015
embryonic limb morphogenesisGO:003032620.015
eye developmentGO:00016542770.015
nephron morphogenesisGO:007202820.015
regulation of cell matrix adhesionGO:000195210.015
cell cycleGO:0007049930.015
negative regulation of metabolic processGO:0009892860.015
neurotransmitter transportGO:000683620.014
axonal defasciculationGO:000741420.014
hematopoietic or lymphoid organ developmentGO:00485341910.014
heart loopingGO:0001947940.014
response to oxygen containing compoundGO:1901700550.014
peptide transportGO:001583310.014
negative regulation of kinase activityGO:003367340.014
meiotic cell cycle processGO:190304630.014
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.014
endocardial cushion morphogenesisGO:000320330.014
actin polymerization or depolymerizationGO:000815420.014
phagocytosis engulfmentGO:000691110.014
positive regulation of transcription dna templatedGO:0045893570.014
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.014
negative regulation of dna replicationGO:000815620.014
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233290.014
negative regulation of protein serine threonine kinase activityGO:007190120.014
regulation of axonogenesisGO:0050770320.014
cartilage developmentGO:0051216960.014
cell growthGO:0016049570.014
cellular lipid metabolic processGO:0044255360.014
regulation of carbohydrate metabolic processGO:000610940.014
activin receptor signaling pathwayGO:003292480.014
response to drugGO:004249330.013
determination of left right asymmetry in nervous systemGO:003554540.013
germ line stem cell maintenanceGO:003071820.013
protein acetylationGO:000647320.013
negative regulation of oocyte developmentGO:006028320.013
cellular amine metabolic processGO:004410620.013
membrane invaginationGO:001032410.013
guanosine containing compound catabolic processGO:190106920.013
regulation of inflammatory responseGO:005072720.013
regulation of macromolecule metabolic processGO:00602553170.013
specification of axis polarityGO:006500140.013
positive regulation of epithelial cell differentiationGO:003085820.013
phosphorus metabolic processGO:00067931090.013
nephron epithelium morphogenesisGO:007208810.013
nuclear importGO:005117030.013
stem cell divisionGO:001714510.013
g1 s transition of mitotic cell cycleGO:000008210.013
regulation of purine nucleotide catabolic processGO:003312120.013
regulation of cell shapeGO:000836010.013
central nervous system neuron differentiationGO:0021953740.013
response to external biotic stimulusGO:0043207970.013
regulation of biological qualityGO:00650082630.013
lamellipodium organizationGO:009758110.013
establishment of localization in cellGO:0051649770.013
organic substance transportGO:0071702580.013
negative chemotaxisGO:005091910.013
organonitrogen compound metabolic processGO:1901564740.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
response to other organismGO:0051707970.013
negative regulation of protein complex assemblyGO:003133310.013
cell projection assemblyGO:0030031640.013
regulation of cytoplasmic transportGO:190364940.013
cell migrationGO:00164772370.013
mitotic cell cycleGO:0000278640.012
purine ribonucleoside monophosphate catabolic processGO:000916940.012
positive regulation of cellular amine metabolic processGO:003324000.012
negative regulation of protein transportGO:005122430.012
establishment of organelle localizationGO:0051656450.012
female sex differentiationGO:004666040.012
angiogenesisGO:00015251580.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.012
embryonic heart tube developmentGO:00350501330.012
sleepGO:003043110.012
negative regulation of protein localization to nucleusGO:190018120.012
cellular modified amino acid metabolic processGO:000657530.012
negative regulation of nucleocytoplasmic transportGO:004682320.012
carbohydrate derivative metabolic processGO:1901135610.012
carbohydrate homeostasisGO:003350010.012
production of molecular mediator of immune responseGO:000244020.012
regulation of cellular carbohydrate metabolic processGO:001067540.012
regulation of gtpase activityGO:004308720.012
protein localization to plasma membraneGO:007265910.012
development of primary female sexual characteristicsGO:004654540.012
catabolic processGO:0009056320.012
negative regulation of cellular catabolic processGO:003133030.012
protein targeting to nucleusGO:004474430.011
growthGO:00400071740.011
purine nucleoside monophosphate catabolic processGO:000912840.011
urogenital system developmentGO:0001655970.011
defense responseGO:0006952470.011
response to stressGO:00069502630.011
neurological system processGO:0050877620.011
post golgi vesicle mediated transportGO:000689210.011
positive regulation of biosynthetic processGO:0009891680.011
lateral line system developmentGO:0048925760.011
pancreas developmentGO:0031016840.011
negative regulation of intracellular transportGO:003238730.011
positive regulation of muscle organ developmentGO:004863610.011
positive regulation of rna biosynthetic processGO:1902680570.011
lamellipodium assemblyGO:003003210.011
cellular response to growth factor stimulusGO:0071363390.011
negative regulation of biosynthetic processGO:0009890550.011
glucocorticoid metabolic processGO:000821120.011
hormone mediated signaling pathwayGO:000975590.011
mitotic cell cycle processGO:1903047480.011
negative regulation of map kinase activityGO:004340720.011
cellular protein metabolic processGO:00442671290.011
neuroblast proliferationGO:000740520.011
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.011
specification of organ positionGO:001015930.011
synaptic vesicle recyclingGO:003646510.011
internal peptidyl lysine acetylationGO:001839320.011
regulation of transcription from rna polymerase ii promoterGO:00063571140.011
neuron projection developmentGO:00311751800.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
nephron tubule morphogenesisGO:007207810.011
positive regulation of neuron deathGO:190121610.011
macromolecule localizationGO:0033036540.011
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.011
connective tissue developmentGO:0061448990.011
circulatory system processGO:0003013870.011
cell fate specificationGO:0001708680.011
positive regulation of chromosome organizationGO:200125210.011
long chain fatty acid transportGO:001590910.011
hard palate developmentGO:006002240.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.011
sensory system developmentGO:0048880760.011
somitogenesisGO:0001756870.011
positive regulation of cellular catabolic processGO:003133130.011
ribonucleoside monophosphate catabolic processGO:000915840.011
cation transmembrane transportGO:0098655650.010
regulation of gtp catabolic processGO:003312420.010
protein secretionGO:000930610.010
negative regulation of transcription dna templatedGO:0045892450.010
negative regulation of mapk cascadeGO:004340940.010
chromosome organization involved in meiosisGO:007019210.010
cellular response to external stimulusGO:007149620.010
response to lipidGO:0033993600.010
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetryGO:1900094170.010
myeloid cell developmentGO:0061515320.010
regulation of epithelial to mesenchymal transitionGO:001071730.010
cellular response to oxygen containing compoundGO:1901701200.010
positive regulation of cytokine productionGO:000181920.010
single organism membrane fusionGO:004480120.010
macromolecule modificationGO:00434121110.010
regulation of protein ubiquitinationGO:003139630.010
positive regulation of multicellular organismal processGO:0051240520.010

raf1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
musculoskeletal system diseaseDOID:1700.031
cancerDOID:16200.018
organ system cancerDOID:005068600.018
disease of cellular proliferationDOID:1456600.018
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.017
nervous system diseaseDOID:86300.016
connective tissue diseaseDOID:6500.014
bone diseaseDOID:008000100.014
muscular diseaseDOID:008000000.012
muscle tissue diseaseDOID:6600.012
myopathyDOID:42300.012