Danio rerio

18 known processes

nav3

neuron navigator 3

(Aliases: wu:fa05f06,cb419)

nav3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna biosynthetic processGO:00327741810.856
cellular component morphogenesisGO:00329893360.722
Worm
gene expressionGO:00104672520.680
nucleic acid metabolic processGO:00903042440.495
rna metabolic processGO:00160702190.461
regulation of transcription dna templatedGO:00063552130.448
transcription dna templatedGO:00063511810.405
cell substrate adhesionGO:003158940.390
regulation of rna biosynthetic processGO:20011412130.383
chordate embryonic developmentGO:00430092710.368
positive regulation of biological processGO:00485182530.338
Worm
transcription from rna polymerase ii promoterGO:0006366800.319
hepaticobiliary system developmentGO:0061008980.310
heart developmentGO:00075073130.286
apoptotic processGO:00069151160.284
cell morphogenesis involved in differentiationGO:00009041950.268
Worm
agingGO:000756820.263
immune system developmentGO:00025201910.262
regulation of nucleobase containing compound metabolic processGO:00192192500.261
stem cell differentiationGO:00488631170.246
negative regulation of cell growthGO:003030870.237
nucleobase containing compound metabolic processGO:00061392740.234
muscle structure developmentGO:00610611960.234
Worm
cellular nitrogen compound biosynthetic processGO:00442712180.225
response to drugGO:004249330.225
morphogenesis of an epitheliumGO:00020093330.216
vasculature developmentGO:00019442780.215
regulation of transcription from rna polymerase ii promoterGO:00063571140.207
cellular aromatic compound metabolic processGO:00067252950.198
regulation of epithelial cell proliferationGO:005067830.197
regulation of nucleic acid templated transcriptionGO:19035062130.197
regulation of gene expressionGO:00104682650.191
hematopoietic or lymphoid organ developmentGO:00485341910.191
cell surface receptor signaling pathwayGO:00071663250.191
mesenchymal cell developmentGO:0014031780.182
sensory organ developmentGO:00074233930.181
regulation of rna metabolic processGO:00512522240.175
gland developmentGO:00487321430.174
negative regulation of cellular processGO:00485232830.173
muscle cell differentiationGO:00426921390.173
regulation of metabolic processGO:00192223590.171
positive regulation of transcription dna templatedGO:0045893570.170
embryo development ending in birth or egg hatchingGO:00097922710.170
cell motilityGO:00488702440.168
Worm
response to stressGO:00069502630.160
regulation of cellular metabolic processGO:00313233200.156
regulation of nitrogen compound metabolic processGO:00511712510.155
positive regulation of rna metabolic processGO:0051254590.147
blood vessel developmentGO:00015682460.136
regionalizationGO:00030022740.135
regulation of apoptotic processGO:0042981980.135
regulation of macromolecule biosynthetic processGO:00105562250.134
cell projection organizationGO:00300302840.133
Worm
regulation of biosynthetic processGO:00098892500.132
neural crest cell differentiationGO:0014033720.127
regulation of neurogenesisGO:0050767870.122
Worm
regulation of response to stimulusGO:00485832690.121
aromatic compound biosynthetic processGO:00194382170.116
heterocycle biosynthetic processGO:00181302150.114
regulation of primary metabolic processGO:00800903110.112
regulation of cellular biosynthetic processGO:00313262450.108
deathGO:00162651210.106
heterocycle metabolic processGO:00464832900.106
negative regulation of axon extension involved in axon guidanceGO:004884310.106
central nervous system developmentGO:00074173870.105
embryonic skeletal system morphogenesisGO:0048704930.104
signal transductionGO:00071654550.100
Worm
cellular macromolecule biosynthetic processGO:00346452240.100
angiogenesisGO:00015251580.099
neuron differentiationGO:00301823530.096
Worm
cytoskeleton organizationGO:0007010960.095
hemopoiesisGO:00300971830.094
organelle assemblyGO:00709251100.094
regulation of cell deathGO:00109411030.092
programmed cell deathGO:00125011190.092
organic cyclic compound metabolic processGO:19013603010.092
somite developmentGO:0061053960.092
mesenchyme developmentGO:00604851270.091
nucleobase containing compound biosynthetic processGO:00346542050.091
primary neural tube formationGO:001402010.090
cellular macromolecule metabolic processGO:00442603910.089
anterior posterior pattern specificationGO:00099521520.089
embryonic organ developmentGO:00485683810.089
striated muscle cell differentiationGO:00511461290.089
cell matrix adhesionGO:000716040.088
ameboidal type cell migrationGO:00016671430.086
Worm
negative regulation of axon guidanceGO:190266810.086
regulation of cell substrate adhesionGO:001081010.085
nucleic acid templated transcriptionGO:00976591810.084
negative regulation of programmed cell deathGO:0043069580.082
multicellular organism growthGO:003526440.082
Worm
negative regulation of cell developmentGO:0010721260.080
response to woundingGO:00096111160.078
somitogenesisGO:0001756870.076
tube morphogenesisGO:00352393490.075
Worm
cellular response to oxygen levelsGO:007145310.074
macromolecule biosynthetic processGO:00090592270.073
positive regulation of rna biosynthetic processGO:1902680570.073
facial nerve developmentGO:002156130.073
mesenchymal cell differentiationGO:0048762870.072
liver developmentGO:0001889960.072
regulation of establishment of protein localizationGO:007020140.072
regulation of stem cell differentiationGO:200073640.070
negative regulation of cell deathGO:0060548600.070
axonogenesisGO:00074091520.069
Worm
regulation of cellular macromolecule biosynthetic processGO:20001122220.069
brain developmentGO:00074202930.069
response to hormoneGO:0009725480.068
positive regulation of nucleobase containing compound metabolic processGO:0045935690.067
synaptic target recognitionGO:000803910.067
regulation of programmed cell deathGO:00430671010.067
digestive tract morphogenesisGO:00485462310.066
Worm
larval developmentGO:000216420.066
cellular nitrogen compound metabolic processGO:00346412900.064
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092500.064
system processGO:00030081850.063
cardiocyte differentiationGO:0035051440.061
cellular component movementGO:00069283350.061
Worm
immune system processGO:00023762410.061
cell morphogenesis involved in neuron differentiationGO:00486671630.060
Worm
regulation of protein transportGO:005122330.060
establishment of localizationGO:00512342440.060
Worm
neuron recognitionGO:0008038180.060
negative regulation of apoptotic processGO:0043066550.059
regulation of signalingGO:00230512350.058
embryonic skeletal joint developmentGO:007249830.057
positive regulation of nitrogen compound metabolic processGO:0051173690.057
neuron developmentGO:00486662620.057
Worm
epithelial tube morphogenesisGO:00605621480.056
positive regulation of transportGO:005105020.056
regulation of cell differentiationGO:00455951420.055
Worm
ear developmentGO:00435831270.054
positive regulation of macromolecule metabolic processGO:0010604930.054
positive regulation of gene expressionGO:0010628710.053
regenerationGO:0031099910.052
negative regulation of neurogenesisGO:0050768200.051
cellular biosynthetic processGO:00442492860.051
nitrogen compound metabolic processGO:00068073190.051
organic substance biosynthetic processGO:19015762890.051
generation of neuronsGO:00486993850.050
Worm
response to organic cyclic compoundGO:0014070510.050
organic cyclic compound biosynthetic processGO:19013622230.050
regulation of synapse organizationGO:005080730.049
regulation of signal transductionGO:00099662250.049
response to chemicalGO:00422213200.048
Worm
central nervous system neuron differentiationGO:0021953740.047
negative regulation of biological processGO:00485193040.047
epithelial tube formationGO:0072175190.047
response to oxygen levelsGO:0070482250.047
muscle cell developmentGO:00550011150.046
negative chemotaxisGO:005091910.045
circadian sleep wake cycleGO:004274520.045
stem cell developmentGO:0048864820.045
regulation of multicellular organismal processGO:00512392770.044
Worm
regulation of nucleocytoplasmic transportGO:004682220.044
blood vessel morphogenesisGO:00485142160.044
response to organic substanceGO:00100331530.044
cellular component assembly involved in morphogenesisGO:00109271070.043
long chain fatty acid transportGO:001590910.043
cellular component assemblyGO:00226071700.043
neurological system processGO:0050877620.043
regulation of bone mineralizationGO:003050020.043
cell proliferationGO:0008283800.042
glial cell migrationGO:000834730.042
regulation of developmental processGO:00507932470.041
Worm
forebrain cell migrationGO:002188510.041
head developmentGO:00603223030.041
cell recognitionGO:0008037190.040
cell cycleGO:0007049930.040
protein importGO:001703830.039
positive regulation of metabolic processGO:00098931080.039
cellular response to estrogen stimulusGO:0071391240.039
regulation of protein localization to nucleusGO:190018020.038
cell deathGO:00082191210.038
eye morphogenesisGO:00485921440.038
establishment of protein localization to organelleGO:007259440.038
camera type eye developmentGO:00430102220.038
regulation of protein targetingGO:190353320.037
macromolecular complex assemblyGO:0065003350.037
lipid storageGO:001991510.037
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101220.036
negative regulation of cell differentiationGO:0045596460.036
gastrulationGO:00073692080.036
Worm
cell cycle g1 s phase transitionGO:004484310.036
negative regulation of nitrogen compound metabolic processGO:0051172590.035
response to endogenous stimulusGO:0009719830.035
taxisGO:00423301090.035
Worm
dorsal ventral pattern formationGO:00099531250.035
regulation of synapse assemblyGO:005196330.033
protein complex subunit organizationGO:0071822460.033
regulation of cysteine type endopeptidase activityGO:2000116210.033
cellular protein complex assemblyGO:0043623190.033
sensory organ morphogenesisGO:00905962000.033
actomyosin structure organizationGO:0031032530.033
single organism organelle organizationGO:19025891990.032
post embryonic organ developmentGO:004856940.032
skeletal system developmentGO:00015011810.032
positive regulation of cellular biosynthetic processGO:0031328680.032
regulation of fatty acid metabolic processGO:001921710.032
localization of cellGO:00516742440.031
Worm
positive regulation of cell cycleGO:004578730.031
cellular response to chemical stimulusGO:00708871570.031
developmental growthGO:00485891660.031
Worm
digestive tract developmentGO:00485652650.031
Worm
negative regulation of nucleobase containing compound metabolic processGO:0045934590.030
cellular response to hypoxiaGO:007145610.030
embryonic hemopoiesisGO:0035162530.030
sensory perceptionGO:0007600390.030
homeostasis of number of cellsGO:0048872620.030
determination of bilateral symmetryGO:00098552040.030
muscle tissue developmentGO:00605371100.030
segmentationGO:0035282970.030
cardiac cell developmentGO:0055006210.030
cell growthGO:0016049570.029
Worm
response to external biotic stimulusGO:0043207970.029
lipid oxidationGO:003444010.029
cellular response to hormone stimulusGO:0032870390.029
embryonic skeletal system developmentGO:0048706970.029
negative regulation of response to stimulusGO:00485851040.029
neuron projection morphogenesisGO:00488121610.029
Worm
cellular response to endogenous stimulusGO:0071495680.028
outflow tract morphogenesisGO:000315110.028
regulation of macromolecule metabolic processGO:00602553170.028
negative regulation of stem cell differentiationGO:200073720.028
positive regulation of cellular processGO:00485222010.028
Worm
negative regulation of transcription from rna polymerase ii promoterGO:0000122160.028
protein localization to nucleusGO:003450430.028
meiotic nuclear divisionGO:000712640.027
olfactory lobe developmentGO:002198840.027
negative regulation of developmental processGO:0051093650.027
thymus developmentGO:0048538100.027
positive regulation of programmed cell deathGO:0043068290.026
determination of left right symmetryGO:00073681790.026
protein complex biogenesisGO:0070271300.026
muscle attachmentGO:001620390.026
Worm
skeletal system morphogenesisGO:00487051020.026
nuclear transportGO:005116940.026
hematopoietic progenitor cell differentiationGO:0002244230.026
posttranscriptional regulation of gene expressionGO:0010608140.026
tube closureGO:006060610.026
rhombomere developmentGO:0021546190.026
positive regulation of macromolecule biosynthetic processGO:0010557590.025
macromolecular complex subunit organizationGO:0043933740.025
carbohydrate homeostasisGO:003350010.025
regulation of cytokine productionGO:000181730.025
regulation of multicellular organism growthGO:004001440.025
Worm
regulation of cellular amino acid metabolic processGO:000652100.025
protein import into nucleusGO:000660630.025
negative regulation of cell communicationGO:0010648960.024
negative regulation of gliogenesisGO:001401410.024
adult behaviorGO:003053420.024
urogenital system developmentGO:0001655970.024
regulation of meiotic cell cycleGO:005144510.024
negative regulation of developmental growthGO:004864090.024
negative regulation of signal transductionGO:0009968940.024
cellular ketone metabolic processGO:0042180110.024
axon guidanceGO:0007411860.023
Worm
axonal defasciculationGO:000741420.023
negative regulation of macromolecule biosynthetic processGO:0010558480.023
bmp signaling pathwayGO:0030509520.023
cellular amino acid metabolic processGO:000652070.023
cell morphogenesisGO:00009022890.023
Worm
circadian sleep wake cycle sleepGO:005080210.023
embryonic heart tube morphogenesisGO:00031431080.023
forebrain developmentGO:0030900960.023
negative regulation of epithelial cell migrationGO:001063310.023
negative regulation of synapse assemblyGO:005196420.023
regulation of anatomical structure morphogenesisGO:00226031300.022
Worm
response to hypoxiaGO:0001666250.022
cardiac muscle cell differentiationGO:0055007300.022
regulation of cell communicationGO:00106462320.022
striated muscle tissue developmentGO:00147061100.022
nucleocytoplasmic transportGO:000691340.022
muscle organ developmentGO:00075171010.022
Worm
olfactory bulb developmentGO:002177240.022
renal system developmentGO:0072001940.021
negative regulation of dna replicationGO:000815620.021
regulation of cell developmentGO:00602841000.021
Worm
skin developmentGO:0043588540.021
positive regulation of cellular amino acid metabolic processGO:004576400.021
epithelial to mesenchymal transitionGO:0001837210.021
cellular component biogenesisGO:00440851780.021
blood coagulation fibrin clot formationGO:007237830.021
inner ear developmentGO:00488391260.021
specification of symmetryGO:00097992040.021
heart morphogenesisGO:00030071560.020
branching morphogenesis of a nerveGO:004875540.020
cellular macromolecular complex assemblyGO:0034622240.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169420.020
response to ketoneGO:190165410.020
negative regulation of protein kinase b signalingGO:005189820.020
nuclear importGO:005117030.020
stem cell maintenanceGO:001982740.020
cognitionGO:005089010.020
cranial suture morphogenesisGO:006036310.020
convergent extensionGO:00600261180.020
response to alkaloidGO:004327920.020
cellular response to organic substanceGO:00713101050.020
facial nerve morphogenesisGO:002161010.020
regulation of epithelial to mesenchymal transitionGO:001071730.019
craniofacial suture morphogenesisGO:009709420.019
auditory receptor cell fate determinationGO:004266820.019
developmental growth involved in morphogenesisGO:0060560860.019
Worm
female sex differentiationGO:004666040.019
peptidyl serine phosphorylationGO:001810510.019
ventricular cardiac muscle cell developmentGO:005501550.019
viral processGO:001603210.019
g1 s transition of mitotic cell cycleGO:000008210.019
maintenance of locationGO:005123540.019
regulation of biological qualityGO:00650082630.019
Worm
female gonad developmentGO:000858540.018
positive regulation of cellular metabolic processGO:0031325940.018
negative regulation of cell morphogenesis involved in differentiationGO:001077180.018
stem cell proliferationGO:007208940.018
biosynthetic processGO:00090582940.018
enzyme linked receptor protein signaling pathwayGO:00071671060.018
response to hexoseGO:000974630.018
angioblast cell migration involved in selective angioblast sproutingGO:003547540.018
single organism nuclear importGO:190259330.018
negative regulation of protein phosphorylationGO:000193340.018
syncytium formation by plasma membrane fusionGO:0000768120.018
positive regulation of muscle organ developmentGO:004863610.018
wound healingGO:0042060900.018
semicircular canal formationGO:006087640.017
tissue regenerationGO:0042246740.017
positive regulation of cellular amine metabolic processGO:003324000.017
response to estrogenGO:0043627270.017
establishment of localization in cellGO:0051649770.017
regulation of transmembrane transporter activityGO:002289820.017
growthGO:00400071740.017
Worm
single organism behaviorGO:0044708240.017
protein complex assemblyGO:0006461300.017
extracellular matrix assemblyGO:008502910.017
lateral inhibitionGO:004633110.017
regulation of cellular ketone metabolic processGO:001056570.017
cellular response to growth factor stimulusGO:0071363390.017
cardiac chamber developmentGO:0003205190.016
protein metabolic processGO:00195381830.016
defense responseGO:0006952470.016
regulation of cell proliferationGO:0042127370.016
negative regulation of rna biosynthetic processGO:1902679450.016
positive regulation of biosynthetic processGO:0009891680.016
formation of anatomical boundaryGO:0048859140.016
sarcomere organizationGO:0045214260.016
actin filament based processGO:0030029640.016
embryonic epithelial tube formationGO:0001838170.016
neuron projection guidanceGO:0097485860.016
Worm
negative regulation of multicellular organismal processGO:0051241690.016
positive regulation of cell divisionGO:005178120.016
extrinsic apoptotic signaling pathway in absence of ligandGO:009719210.015
phagocytosisGO:000690930.015
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.015
response to growth factorGO:0070848390.015
neural tube formationGO:0001841160.015
regulation of cellular amine metabolic processGO:003323800.015
preganglionic parasympathetic nervous system developmentGO:002178360.015
central nervous system neuron developmentGO:0021954290.015
regulation of sodium ion transportGO:000202820.015
intracellular signal transductionGO:0035556850.015
regulation of axon guidanceGO:190266780.015
pharyngeal muscle developmentGO:004328240.015
somatic muscle developmentGO:000752540.015
blood vessel endothelial cell migrationGO:0043534180.015
actin cytoskeleton organizationGO:0030036630.015
positive regulation of nucleic acid templated transcriptionGO:1903508570.015
rhombomere formationGO:0021594120.015
regulation of neural precursor cell proliferationGO:200017730.015
cell part morphogenesisGO:00329902460.015
Worm
response to decreased oxygen levelsGO:0036293250.015
regulation of stem cell proliferationGO:007209120.015
positive regulation of apoptotic processGO:0043065290.015
regulation of cell morphogenesis involved in differentiationGO:0010769380.015
Worm
regulation of organ growthGO:004662030.015
response to hostGO:007513620.015
negative regulation of cell projection organizationGO:003134590.015
fin developmentGO:0033333770.015
response to abiotic stimulusGO:00096281220.015
peptidyl serine modificationGO:001820920.015
cell migration to the midline involved in heart developmentGO:0003318120.014
fatty acid transportGO:001590810.014
regulation of nervous system developmentGO:0051960900.014
Worm
sleepGO:003043110.014
protein secretionGO:000930610.014
regulation of intracellular protein transportGO:003315730.014
skeletal muscle organ developmentGO:0060538780.014
Worm
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200123910.014
hard palate developmentGO:006002240.014
organelle organizationGO:00069962270.014
digestive system developmentGO:00551232890.014
Worm
rhombomere morphogenesisGO:0021593170.014
cranial nerve developmentGO:0021545420.014
axon developmentGO:00615641660.014
Worm
negative regulation of signalingGO:0023057960.014
negative regulation of neuron differentiationGO:0045665100.013
response to carbohydrateGO:000974330.013
positive regulation of response to stimulusGO:0048584800.013
embryonic cranial skeleton morphogenesisGO:0048701900.013
regulation of axon regenerationGO:004867970.013
regulation of cell adhesionGO:0030155150.013
regulation of cellular carbohydrate metabolic processGO:001067540.013
otic vesicle developmentGO:0071599420.013
sprouting angiogenesisGO:0002040530.013
cell projection morphogenesisGO:00488582440.013
Worm
multicellular organismal response to stressGO:003355520.013
startle responseGO:000196440.013
response to glucoseGO:000974930.013
regulation of intracellular signal transductionGO:1902531570.013
regulation of synaptic growth at neuromuscular junctionGO:000858210.013
eye developmentGO:00016542770.013
neurotransmitter transportGO:000683620.013
negative regulation of epithelial cell proliferationGO:005068010.013
organ formationGO:0048645170.013
regulation of cell projection assemblyGO:006049140.013
regulation of bindingGO:005109830.013
cardiac atrium morphogenesisGO:000320920.012
regulation of heart growthGO:006042020.012
fin regenerationGO:0031101510.012
heart contractionGO:0060047710.012
regulation of protein import into nucleusGO:004230620.012
regulation of dna replicationGO:000627530.012
regulation of calcium ion transportGO:005192420.012
dorsal ventral axis specificationGO:0009950140.012
development of primary female sexual characteristicsGO:004654540.012
response to light stimulusGO:0009416460.012
response to estradiolGO:003235560.012
negative regulation of neural precursor cell proliferationGO:200017810.012
embryonic skeletal joint morphogenesisGO:006027230.012
negative regulation of growthGO:0045926100.012
chromosome organizationGO:0051276310.012
regulation of cytoplasmic transportGO:190364940.012
biological adhesionGO:0022610400.012
kidney developmentGO:0001822920.012
membrane organizationGO:0061024210.011
regulation of multicellular organismal developmentGO:20000262230.011
Worm
peripheral nervous system developmentGO:0007422550.011
positive regulation of reproductive processGO:200024320.011
myofibril assemblyGO:0030239480.011
determination of ventral identityGO:0048264210.011
negative regulation of blood circulationGO:190352320.011
regulation of cell shapeGO:000836010.011
neuronal action potentialGO:0019228180.011
extrinsic apoptotic signaling pathwayGO:009719130.011
neuroblast proliferationGO:000740520.011
cell substrate junction assemblyGO:000704420.011
cellular response to decreased oxygen levelsGO:003629410.011
autonomic nervous system developmentGO:0048483190.011
regulation of extrinsic apoptotic signaling pathwayGO:200123630.011
response to monosaccharideGO:003428430.011
negative regulation of cellular biosynthetic processGO:0031327550.011
oxoacid metabolic processGO:0043436310.011
kupffer s vesicle developmentGO:0070121500.011
response to other organismGO:0051707970.011
negative regulation of gene expressionGO:0010629650.011
reproductive structure developmentGO:004860850.011
negative regulation of muscle cell differentiationGO:005114810.011
hindbrain developmentGO:0030902910.011
cell cycle arrestGO:000705010.011
negative regulation of signal transduction in absence of ligandGO:190109910.011
cellular localizationGO:0051641970.011
positive regulation of endothelial cell differentiationGO:004560320.010
regulation of endothelial cell differentiationGO:004560130.010
fatty acid beta oxidationGO:000663510.010
positive regulation of immune effector processGO:000269930.010
signal transduction in absence of ligandGO:003803410.010
regulation of molecular functionGO:0065009700.010
ventricular cardiac muscle tissue morphogenesisGO:005501020.010
striated muscle cell developmentGO:00550021080.010
cell migration involved in gastrulationGO:0042074790.010
Worm
regulation of response to biotic stimulusGO:000283120.010
response to oxygen containing compoundGO:1901700550.010
parasympathetic nervous system developmentGO:004848660.010
dendrite guidanceGO:007098300.010
morphogenesis of embryonic epitheliumGO:0016331300.010
locomotory behaviorGO:0007626340.010

nav3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.165
disease of anatomical entityDOID:700.165
musculoskeletal system diseaseDOID:1700.057
muscle tissue diseaseDOID:6600.056
cardiomyopathyDOID:005070000.056
heart diseaseDOID:11400.056
muscular diseaseDOID:008000000.056
intrinsic cardiomyopathyDOID:006003600.056
myopathyDOID:42300.056
connective tissue diseaseDOID:6500.025
disease of cellular proliferationDOID:1456600.025
cancerDOID:16200.025
organ system cancerDOID:005068600.023
dysostosisDOID:193400.018
bone diseaseDOID:008000100.018
bone development diseaseDOID:008000600.018
disease of metabolismDOID:001466700.014
synostosisDOID:1197100.012